Background:
To efficiently deconstruct recalcitrant plant biomass to fermentable sugars in industrial processes, biocatalysts of higher performance and lower cost are required. The genetic diversity found in the metagenomes of natural microbial biomass decay communities may harbor such enzymes. Our goal was to discover and characterize new glycoside hydrolases (GHases) from microbial biomass decay communities, especially those from unknown or never-been-cultivated microorganisms.
Results:
From the metagenome sequences of an anaerobic microbial community actively decaying poplar biomass, we identified approximately 4,000 GHase homologues. Based on homology to GHase families/activities of interest and the quality of the sequences, candidates were selected for full length cloning and subsequent expression. As an alternative strategy, a metagenome expression library was constructed and screened for GHase activities. These combined efforts resulted in the cloning of four novel GHases that could be successfully expressed in E. coli. Further characterization showed that two enzymes showed significant activity on p-nitrophenyl-alpha-L-arabinofuranoside, one enzyme had significant activity against p-nitrophenyl-beta-D-glucopyranoside, and one enzyme showed significant activity against p-nitrophenyl-beta-D-xylopyranoside. Enzymes were also tested in the presence of ionic liquids.
Conclusions:
Metagenomics provides a good resource for mining novel biomass degrading enzymes and for screening of cellulolytic enzyme activities. The four GHases that were cloned may have potential application for deconstruction of biomass pretreated with ionic liquids, as they remain active in the presence of up to 20% ionic liquid (except for 1-ethyl-3-methylimidazolium diethyl phosphate). Alternatively, ionic liquids might be used to immobilize or stabilize these enzymes for minimal solvent processing of biomass.
Monthly Archives: August 2011
Are Taller People at Heightened Cancer Risk?
(HealthDay News) -- Tall folks may be more likely than shorter people to develop cancer, new British research says.
Among women, the risk of breast, ovarian, uterine and bowel cancer, leukemia or melanoma appears to go up about 16 percent for every 4-inch bump in stature, the researchers said.
"Taller women in our study had increased risk of a wide range of cancers," said study co-author Jane Green, from the cancer epidemiology unit at the University of Oxford in England. "And all the evidence from past studies is that this link is seen equally in men and women."
The findings also suggest that gains in height over the 20th century -- Europeans' average height grew nearly half an inch per decade -- might help explain some of the cancer differences seen in recent generations, the researchers said. Read more...
Ayurtox for Body Detoxification
Green tea better at preventing cancer and dementia than previously thought
For years, we covered the mounting research linking green tea and its extracts to a host of disease-fighting benefits -- from halting the progression of chronic lymphocytic leukemia (http://www.dreddyclinic.com/forum/viewtopic.php?f=78&t=22310&view=previous) and reducing the risk of cardiovascular disease to protecting the oxygen-deprived brain from memory loss (http://www.dreddyclinic.com/forum/viewtopic.php?f=23&t=22813) and preventing breast cancer (http://www.dreddyclinic.com/forum/viewtopic.php?f=15&t=24272, http://www.dreddyclinic.com/forum/viewforum.php?f=69&start=50). It almost sounds too good to be true, right? Actually, a new study has revealed that green tea is an even more incredible natural health enhancer than anyone knew previously.
Scientists at Newcastle University in the United Kingdom have just discovered that when green tea is consumed, the digestive process in the gut creates powerful chemicals that work to protect the body against two of humankind's most dreaded diseases -- Alzheimer's and cancer. The research, headed by Dr. Ed Okello, was recently published in the academic journal Phytomedicine. Read more...
The Seasteading Institute July 2011 Newsletter
The Seasteading Institute - July 2011 Newsletter
Greetings Friends of Seasteading,
Our vision for seasteading is to improve government through competition, and my personal talents lie in seeing possibilities and starting initiatives. Many groups and organizations in the past have tried their hand at the audacious task of creating innovative societies, and I saw the possibility for seasteading to powerfully advance this idea with our unique approach. Thus was born The Seasteading Institute in 2008, as a marvelous addition to the practical politics portfolio.
Much important movement-building and research work remains here at the Institute, and we believe there is also important work to be done in the commercial sector, by creating businesses that benefit individuals through better laws. From both a personal and organizational standpoint, the time is right for me to pursue the vision of government innovation by shifting my primary focus to creating new commercial ventures that will complement the work here at the Institute. I look forward to sharing more details about my projects as they become more solid.
I’m excited to announce that I've found a great executive team to take over and continue to grow The Seasteading Institute: Michael Keenan and Randy Hencken. I will stay significantly involved as Chairman of the Board, media and diplomatic spokesperson, and strategic advisor, as well as promoting seasteading through our in-progress book Seasteading: How Ocean Cities Will Reinvent Politics. While it is a bittersweet moment for me, I believe my talents are best suited to continuing to expand our portfolio of ventures, while Michael and Randy have the passion and talent to take The Seasteading Institute to the next level.
Similarly, two other staff members—Max Marty, Director of Business Strategy and Dario Mutzabdzija, Director of Legal Strategy—are wrapping up their research and preparing to start Blue Seed, a shipsteading venture, as their contribution to expanding the movement. A commercial sector is vital to seasteading progress, and so we’re thrilled that Max and Dario are helping lead the charge to this next frontier for seasteading, and we’re excited to see where their adventure takes them.
As you can see in this newsletter, we have lots of great progress to report, and Michael and Randy will continue to add new programs to advance the seasteading mission. If you’re interested in reading about the details of our motivation for this expansion, the staff and program changes, and the new ventures, this page has more information.
In service of seasteading,
Patri Friedman
Table of Contents
- Engineering Report Released: "Parametric Analysis of Candidate Configurations for Early Seastead Platforms..."
- First Legal Research Report Released: "Charting the Course: Toward a Seasteading Legal Strategy"
- San Francisco Bay Summer Meet-Up, August 17
- Featured Ambassador: Julian Le Roux
- Featured Donor (and Ambassador!): Paul Martin
- Welcome Engineering Interns: Jorge Suarez and Elie Amar
- San Francisco Chronicle Placed Us on the Front Page
- Ephemerisle Demonstrates Success in Crowd-Sourcing a Seasteading-Esque Event
Looking Back: Bathing Caps
Hanging out at the beach in a bathing cap is not something we really do anymore, but these images — real and painted — sure make it look fun.
This painting is by one of my favorite Washington, DC-based artists, Gregory Ferrand.
Aruba’s Fisherman’s Huts (Hadikurari) Beach – Hold On To Your Hat!
It must be the way the coast curves inwardly between Palm and Malmok Beaches; whatever the cause, Aruba’s Fisherman’s Huts Beach (Hadikurari) is incredibly windy, and it’s the place to be if you want to try out (or just) watch some windsurfing. Especially in the summer months, the warm trade winds whip across this beach’s sands and waters at upwards of 20mph, with some gusts reaching the 30s. It’s a true hold-on-to-your-hat (and your sunglasses, and your beach bags) beach.
Although I did not try windsurfing myself, I can attest to the patience of the instructors on this beach; my husband and I watched one teacher try to get a girl to windsurf for well over an hour. It’s apparently a lot harder than it looks, and getting dragged through the water by a lofty sail did not look like the most fun. Once she finally got going though, I was jealous! It looked so carefree and fun.
The water on this beach is quite shallow at first, and not the best for snorkeling due to all of the wind. But, the water is warm year-round and invites lazy wading.
Human spectators aren’t the only visitors to this beach. Keep your eyes peeled for gorgeous turquoise and green lizards. One of them was so friendly that he/she came right up to us and crawled over our hands. The wind doesn’t seem to bother them much, probably because they’re so close to the ground. They’re completely harmless and their scampering adds a touch of frolicking frivolity to the picturesque scene.
IF YOU GO: Take the Arubus and pack a lunch to eat in the shade. Wear sunglasses to protect your eyes from the sand flying around.
Photos: Jenny Bengen-Albert
Looking Back: Men’s Trunks
I stumbled across this Jantzen ad from 1963 and it is too good to not share it with you all.
Looks like prints and a sung fit were pretty popular back then. Here are some versions for the modern man.
Note that most of these trunks are red… just because 1) it’s a universally flattering color, and 2) it looks great against the backdrop of the blue ocean water.
P.S. The Janzten picture is actually a poster that’s for sale on eBay.
Prescription Goggles and Snorkel Masks: No More Contacts Underwater!
I recently learned about something very, very cool, and something I wish I had known about before traveling to Aruba: prescription goggles! As someone who’s worn glasses and contacts since I was 8 years old and who loves to snorkel, this is very exciting. Prescription goggles and prescription masks enable snorkelers to be able to see perfectly without having to worry about their contacts. I don’t know about you, but I have enough problems to worry about when I snorkel: foggy lenses, staying afloat, fish that want to nibble on my toes. I detest having to wear contacts when I’m at the beach because all it takes is one tiny grain of sand and I have to take out my contact, rinse, and then put it back in my now red and severely aggravated eye. I’ve actually never had a problem of losing my contacts in the water (yet!), but I know that’s always a possibility, and it’s nerve-wracking.
I’m still at the beginning stages of my research, but it looks as though you can get prescription goggle for prescriptions as bad as -10; this is actually better than my vision but it’s close enough! Seeing clearly underwater without worries. This is sounding better and better.
The only hiccup I can think of with this product is this: what do you do if you have to take your goggles off? Or what do you do when you get out of the water? Put on glasses? People like me with really bad eyes are, for all intents and purposes, blind without contacts, and I’m not sure how I feel about bringing a pair of glasses with me to the beach…but it’s got to be a better solution than wearing contacts underwater.
It looks like prescription goggles run around $25-$50, but masks range from $100-$300, so they’re more of an investment. Definitely something to think about as I plan my next snorkel expedition.
Photo: Sarah_Ackerman
Looking Back: High-Waisted Bikini Bottoms
Inspired by Sebastien’s Jan & Dean’s Surf City post, as we head into the heat of the summer I’m dedicating a series of blog posts called “Looking Back” to retro swimsuits!
One of the most iconic American images of the bikini is a photograph of Annette Funicello from the 1963 Beach Party movies, a series of summer beach movies with co-star Frankie Avalon. Word on the street is that Annette was instructed to wear bellybutton-covering bikini bottoms by none other than Mr. Walt Disney himself!
The high-waisted bikini bottom is perfect for those ladies who prefer either a) a little modesty, b) a little retro, c) fashion fun, or d) all of the above!
Here are some modern high-waisted versions you can try on for yourself:
Beach Music Series: Jan and Dean’s Surf City
To ignore the classics is a huge mistake. Jan and Dean’s Surf City was the #1 song for two weeks in 1963, was originally titled “Goodie Connie Won’t You Come Back Home” and written by Brian Wilson of the Beach Boys. Wilson gave it to Jan Berry and Dean Torrence who finished writing and recording the song in the early 1960s. Here is a fun fact, in 1991, Dean Torrence convinced the city of Huntington Beach, CA to adopt the nickname “Surf City” as Huntington’s nickname.
I was lucky enough to find this video on YouTube of a live Jan and Dean performance of Surf City in 1963. Please note that the opening 5-10 seconds sounds really bad because of the crowd cheering so you may want to go ahead and skip over to 0:05.
Under the Clouds – A Journey to Martinique
I am a fan of travel videos which really gets across the feeling of travel, be it introspective or just plain fun. This particular video, Under the Clouds by Vimeo user Gioacchino Petronicce captures the pay off of a seemingly long haul to paradise. The color tones are fantastic and instead of typical sunny beach vacation the journey takes us into Martinique during the rainy season which Gioacchino shoots quite well.
About the video:
These images and these sounds were recorded during a travel from “Toulouse” to “Paris”, and from “Paris” to “Martinique”. We see the North and the South of “Martinique”, the Atlantic Ocean and the Caribbean Sea, during the rainy season in July, 2011.
This small video was thought before I arrive on the scene. The images were not priority but it’s the sound which guided the shoot and the edition.
Sounds recorded with a zoom H4N (post sync).
Images shot with a tripod and a 7D.
Music ; snow angel summer – Voyager One
2011
Seeing Underwater
Every wonder why we can’t see properly under water? Well, I looked it up. Our eyes are adapted for viewing in a gaseous (air) environment. Light rays bend less through gasses than they would underwater. In water, light rays are refracted much differently. So how does that affect me? Well, if you like to dive or snorkel it affects three key things: Color, Distance and size. We wear goggles to see underwater. The reason why this works is because of the layer of air between the glass making the light refracts “normally” for us. Keep in mind though that with those goggles on, things will look about 33% bigger in freshwater, 34% bigger in saltwater and 25% closer overall. Our color perception underwater changes the deeper you are and the more particles and how muddy/murky it is in the first place. The following is a guide by Luria et al.
A. For murky, turbid water of low visibility (rivers, harbors, etc.)
1. With natural illumination:
a. Fluorescent yellow, orange, and red.
b. Regular yellow, orange, and white.
2. With incandescent illumination:
a. Fluorescent and regular yellow, orange, red and white.
3. With a mercury light source:
a. Fluorescent yellow-green and yellow-orange.
b. Regular yellow and white.
B. For moderately turbid water (sounds, bays, coastal water).
1. With natural illumination or incandescent light source:
a. Any fluorescent in the yellows, oranges, and reds.
b. Regular yellow, orange, and white.
2. With a mercury light source:
a. Fluorescent yellow-green and yellow-orange.
b. Regular yellow and white.
C. For clear water (southern water, deep water off shore, etc.).
1. With any type of illumination fluorescent paints are superior.
a. With long viewing distances, fluorescent green and yellow-green.
b. With short viewing distances, fluorescent orange is excellent.
2. With natural illumination:
a. Fluorescent paints.
b. Regular yellow, orange, and white.
3. With incandescent light source:
a. Fluorescent paints.
b. Regular yellow, orange, and white.
4. With a mercury light source:
a. Fluorescent paints.
b. Regular yellow, white.
The most difficult colors at the limits of visibility with a water
background are dark colors such as gray or black.
Polynesian Black Pearls
French Polynesia's cultured pearls originate on cooperative and private pearl farms on 26 atolls in the Tuamotu Islands. A radiant, perfectly round, smooth, and flawless pearl with a good depth of metallic green/blue can sell for thousands of dollars.
The migrants have landed
Tuesday 2nd August comments: It seems that the summer ‘dead zone’ is finally over, and the first migrants are starting to make their way to the Farnes on their journey to their wintering grounds. Large numbers of waders are beginning to gather on the islands’ rocky shores, and the Farnes has boasted flocks of up to 315 Golden Plover, over 200 Turnstone and 280 Knot.
Arctic and Great Skua are being sighted regularly, with some very close views of the former today as one lingered over the Inner Farne jetty.
Smaller birds are also on the move, with a bright young Willow Warbler showing well on Brownsman on 30th July along with a female Black Redstart. Just to remind us that this wasn’t a one-off early occurrence, we were visited today by a Yellow Wagtail and a moulting adult Black Tern, which showed well for visitors on the rocks to the south of Inner Farne jetty.
Here’s hoping that this is a sign for an oncoming deluge of migrants. We’ll be keeping our eyes to the skies and keeping you all updated!
Lotus Island Michigan
Like much of North America, Michigan is home to some of the most beautiful islands in the world with the added advantage that they are often located on vast fresh water lakes.
One of the newest and most stunning islands to come on the market in Michigan is Lotus Island.Exceptionally unique Tobocman & Lawrence home on Lotus Island with stunning views of Lotus Lake. Escape to your private 1-acre island complete with state of the art contemporary home., featuring an open floor plan for entertaining, expansive walls of windows, spacious rooms and a huge screened porch to enjoy the lake. Stunning grounds with private gardens. Patio stretches to the waterfront and overlooks the lake and fountains. An absolute masterpiece.
For more information visit Private Islands Online
Italians Indulging in Private Islands
Italy is famous for it’s beautiful beaches, and every summer Italians flee the hot and crowded cities for the cool breezes of the coast. According to the Independent, Italians are taking their beach obsession to a whole new level with more of the countries super rich investing in private islands. .
According to the paper last year a record 150 islands, from Croatia’s coast to the Caribbean and the South Seas, were bought by Italians.
Many VIPs who buy them like to keep quiet, but there were unconfirmed reports that Italian fashion designer Giorgio Armani bought a small Greek island for more than £100 million (R1.1 billion).
Customers with £440 000 or more can start enquiring about the coast of Florida, the Gulf of Mexico, or the Maldives. Islands in the Caribbean went for £6.2m.
Islands off the coasts of Norway, Brazil and Greece have also proved a draw for Italian customers.
And according to newspaper La Repubblica, the Italian demand for islands looks set this year to outstrip that of last year.
The choice of islands has never been better, as governments seek to refill coffers emptied by recession. In 2009, Croatia said it was putting its Brioni Islands in the Adriatic on sale, in the hope of making more than £880m.
To read the article visit iol travel.
Solar Powered Self Phone Charger
On many private islands around the world the sun is plentiful but power is at a premium. This is why many island owners are turning to alternative energy sources to power their appliances and products.
One of the most efficient and economical of thse products is the solar powered phone charger. A new solar panel cell phone charging system by Nokero has recently been attracting a lot of attention. The Nokero system can fully charge a dead phone in about one and a half hours, using only the sun.
Nokero designed the panels initially to be used by impoverished villages around the globe that have little access to electricity (although they surprisingly have cell phones). However they would be ideal for anyone living in a remote locations.
Nokero chargers are currently available online in sample-only prices, at $29 and $49. A benefit to all eco-conscious cell phone users, the purchase of Nokero’s chargers by urban customers would increase demand, and potentially drive prices even lower for the intended off grid impoverished cell phone users.
Logan’s Voyage
Logan Horsford’s blog does come with accept or reject buttons (seriously). Click accept because it’s well worth the effort. Once there, you will find an unabashed, in-your-face, these are my experiences tale of his travels. As Logan responded to me at a certain point, “it’s unconventional but I think that could be part of the reason people read it”. I agree completely.
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Post tags: cultural experiences, Europe, Perpetual Travel, solo travel
Marshall accepting applications for new medical school initiative – HNN Huntingtonnews.net
![]() Palm Beach Post | Marshall accepting applications for new medical school initiative HNN Huntingtonnews.net “Through this program, we'll be giving students an in-depth understanding of the processes and preparation for applying to and attending medical school,” said Dr. Shari Clarke, Vice President for Multicultural Affairs at Marshall. ... Marshall accepting applications for new medical school initiativeHuntington Herald Dispatch FAU's first medical students start, joining surge in South Florida medical ...Sun-Sentinel FAU's first class of medical students receive their white coatsWPEC The Republic -Sacramento Bee all 22 news articles » |
DeVry buys Caribbean medical school for $235M – BusinessWeek
DeVry buys Caribbean medical school for $235M BusinessWeek For-profit school chain DeVry Inc. said Thursday that it acquired a medical school in the Caribbean for $235 million as it builds its healthcare-related program offerings. The school, American University of the Caribbean, is privately held and located ... DeVry Inc. buys American University of the Caribbean on St. Maarten for $235 ...Washington Post DeVry Inc. Announces Acquisition of American University of the CaribbeanMarketWatch (press release) DeVry Acquires American University Of The Caribbean For $235 MillionWall Street Journal |