"Getting Naked: The Story of the Aquatic Ape Theory" with Mark Kessell, Observatory, Thursday Feb. 17th

25017_1

This Thursday at Observatory! Hope to see you there.

An illustrated lecture by artist and ex-physician Mark Kessell
Date: Thursday, February 17th
Time: 8:00 PM
Admission: $5
Presented by Morbid Anatomy

Have you ever stepped out of the shower and noticed a naked ape in the mirror? Scientists agree: that’s what you are. But why do we look so different from our very, very, very close relative, the chimpanzee? The Aquatic Ape Theory, first proposed in the 1930’s but developed much more recently, proposes a strange but surprisingly plausible idea: we took a dip in the pool of evolution, paddled about a bit, and by the time we moved to a drier neighborhood we were walking tall, straight and naked. The back-story behind this theory is a tale of scientific in-fighting and elitism as remarkable as the theory itself.

Ex-physician turned artist, Mark Kessell, dishes the dirt on human evolution in a fun-filled and completely un-scientific talk on the world of science. Get the Naked Truth! Get it now. Get it at Observatory.

Mark Kessell is an Australian medical doctor and professional artist working in New York City. Most of his work has a biological or scientific focus. He is represented by Kim Foster Gallery in Chelsea where his next exhibition, “Specimen Box” will open on March 17th, 2011. You can find out more about his work at http://www.studiocyberia.com.

You can find out more about this event on the Observatory website by clicking here and can can access the event on Facebook here. You can get directions to Observatory--which is next door to the Morbid Anatomy Library (more on that here)--by clicking here. You can find out more about Observatory here, join our mailing list by clicking here, and join us on Facebook by clicking here.

Arsenal of plant cell wall degrading enzymes reflects host preference among plant pathogenic fungi

Background:
Discovery and development of novel plant cell wall degrading enzymes is a key step towards more efficient depolymerization of polysaccharides to fermentable sugars for production of liquid transportation biofuels and other bioproducts. The industrial fungus Trichoderma reesei is known to be highly cellulolytic and is a major industrial microbial source for commercial cellulases, xylanases, and other cell wall degrading enzymes. However, enzyme-prospecting research continues to identify opportunities to enhance the activity of T. reesei enzyme preparations by supplementing with enzymatic diversity from other microbes. The goal of this study was to evaluate the enzymatic potential of a broad range of plant pathogenic and non-pathogenic fungi for their ability to degrade plant biomass and isolated polysaccharides.
Results:
Large-scale screening identified a range of hydrolytic activities among 348 unique isolates representing 156 species of plant pathogenic and non-pathogenic fungi. Hierarchical clustering was used to identify groups of species with similar hydrolytic profiles. Among moderately and highly active species, plant pathogenic species were more active than non-pathogens on six of eight substrates tested, with no significant difference seen on the other two substrates. Among pathogenic fungi, greater hydrolysis was seen when tested on biomass and hemicellulose derived from their host plants (commelinoid monocot or dicot). Although T. reesei has a hydrolytic profile that is highly active on cellulose and pretreated biomass, it was less active than some natural isolates of fungi when tested on xylans and untreated biomass.
Conclusions:
Several highly active isolates of plant pathogenic fungi were identified, particularly when tested on xylans and untreated biomass. There were statistically significant preferences for biomass type reflecting the monocot or dicot host preference of the pathogen tested. These highly active fungi are promising targets for further identification and characterization of novel cell wall degrading enzymes for industrial applications.

Types of ovarian activity in women and their significance: the continuum (a reinterpretation of early findings)

BACKGROUND

There are many types of ovarian activity that occur in women. This review provides information on the relationship between the hormone values and the degree of biological response to the hormones including the frequency and degree of uterine bleeding. The continuous process is termed the ‘Continuum’ and is thus similar to other processes in the body.

METHODS

This review draws on information already published from monitoring ovarian activity by urinary oestrogen and pregnanediol measurements using timed 24-h specimens of urine. Much of the rationalization was derived from 5 to 6 year studies of girls progressing from childhood to adulthood, women progressing through menopause, and the return of fertility post-partum. During these times, all the reported types of ovarian activity were encountered.

RESULTS

All cycle types can be understood in terms of steps in the normal maturation of fertility at the beginning of reproductive life, its return post-partum and its demise at menopause. Each step merges into the next and therefore the sequence is termed the ‘Continuum’. Unpredictable movement from fertile to infertile types and back can occur at any time during reproductive life. Stress is a major causative factor. Hormonal definitions for each step, the relevance of the various cycle types in determining fertility and in the initiation of uterine bleeding and the roles of the pituitary hormones in causing them, are presented.

CONCLUSIONS

The findings explain the erratic fertility of women and why ovulation is not always associated with fertility. They provide an understanding of the various types of ovarian activity and their relation to pituitary function, fertility and uterine bleeding.

Oral contraceptives and risk of endometriosis: a systematic review and meta-analysis

BACKGROUND

Combined oral contraceptives (OCs) inhibit ovulation, substantially reduce the volume of menstrual flow and may hypothetically interfere with implantation of refluxed endometrial cells. The aim of this review is to establish if OC use influences the risk of endometriosis.

METHODS

We performed a MEDLINE search to identify all studies published in the last four decades (January 1970 to January 2010) in the English language on the relationship between OC exposure and risk of endometriosis. Two authors abstracted data on standardized forms.

RESULTS

We identified 608 potentially relevant studies and 18 studies (6 cross-sectional, 7 case–control and 5 cohort) were selected. Pooling of the results derived from all the included reports independently from study design, yielded a common relative risk of 0.63 [95% confidence interval (CI), 0.47–0.85] for current OC users, 1.21 (95% CI, 0.94–1.56) for past users and 1.19 (95% CI, 0.89–1.60) for ever users. Methodological drawbacks, such as uncertain temporal relationship between exposure and outcome in cross-sectional studies and suboptimal selection of controls in case–control studies, limit the quality of the available evidence.

CONCLUSIONS

The risk of endometriosis appears reduced during OC use. However, it is not possible to exclude the possibility that the apparent protective effect of OC against endometriosis is the result of postponement of surgical evaluation due to temporary suppression of pain symptoms. Confounding by selection and indication biases may explain the trend towards an increase in risk of endometriosis observed after discontinuation, but further clarification is needed. To date, the hypothesis of recommending OCs for primary prevention of endometriosis does not seem sufficiently substantiated.

Exercise therapy in polycystic ovary syndrome: a systematic review

BACKGROUND

Polycystic ovary syndrome (PCOS) is a common endocrine disorder, affecting 8–12% of women. Lifestyle modification, including increased physical activity, is the first-line approach in managing PCOS. A systematic review was performed to identify and describe the effect of exercise as an independent intervention on clinical outcomes in PCOS.

METHODS

Five databases were searched with no time limit. A pre-specified definition of PCOS was not used. Studies were included if exercise therapy (aerobic and/or resistance) could be evaluated as an independent treatment against a comparison group. Outcomes measured included cardiovascular risk factors [insulin resistance (IR), lipid profiles, blood pressure and weight] and reproductive measures (ovulation, menstrual regularity and fertility outcomes). Quality analysis was performed based on the Cochrane Handbook of Systematic Reviews and the Quality of Reporting of Meta-Analyses checklist.

RESULTS

Eight manuscripts were identified (five randomized controlled trials and three cohort studies). All studies involved moderate intensity physical activity and most were of either 12 or 24 weeks duration with frequency and duration of exercise sessions ranging between studies. The most consistent improvements included improved ovulation, reduced IR (9–30%) and weight loss (4.5–10%). Improvements were not dependant on the type of exercise, frequency or length of exercise sessions.

CONCLUSIONS

Exercise-specific interventions in PCOS are limited. Studies vary considerably in design, intensity and outcome measures; therefore conclusive results remain elusive. Larger, optimally designed studies are needed to both gain insights into the mechanisms of exercise action and to evaluate the public health impact of exercise of PCOS.

Clinical outcomes in relation to the daily dose of recombinant follicle-stimulating hormone for ovarian stimulation in in vitro fertilization in presumed normal responders younger than 39 years: a meta-analysis

BACKGROUND

The optimal ovarian stimulation dose to obtain the best balance between the probability of pregnancy and the risk of complications, while maximizing cost-effectiveness of in vitro fertilization (IVF) treatment, is yet to be established.

METHODS

A systematic search of the electronic databases PubMed, EMBASE and Cochrane library, from 1984 until October 2009 for randomized controlled trials comparing different doses of recombinant FSH in IVF, was performed.

RESULTS

Ten studies (totaling 1952 IVF cycles) were included in the present meta-analysis, comprising patients younger than 39 years with regular menstrual cycle, normal basal FSH levels and two normal ovaries. Comparison was made between studies using a daily dose of 100 versus 200 IU recFSH, and between 150 versus 200 IU recFSH or higher. Although oocyte yield was greater in the >200 IU/day dose group, pregnancy rates were similar compared with lower dose groups. The risk of insufficient response to ovarian stimulation was greatest in the 100 IU/day dose group. The risk of developing ovarian hyperstimulation syndrome was greater in the >200 IU/day dose group. The number of embryos available for cryopreservation was lowest in the 100 IU/day group, but similar comparing the 150 IU/day and the >200 IU/day dose groups.

CONCLUSIONS

This meta-analysis suggests that the optimal daily recFSH stimulation dose is 150 IU/day in presumed normal responders younger than 39 years undergoing IVF. Compared with higher doses, this dose is associated with a slightly lower oocyte yield, but similar pregnancy and embryo cryopreservation rates. Furthermore, the wide spread adherence to this optimal dose will allow for a considerable reduction in IVF costs and complications.

What about gr/gr deletions and male infertility? Systematic review and meta-analysis

BACKGROUND

The impact of gr/gr deletions on male fertility is unclear. These partial deletions of the AZFc region of the Y chromosome have been detected more frequently in infertile patients. However, few individual studies have demonstrated a statistically significant association. This study aims to quantify the strength of association between gr/gr deletions and male infertility, and to explore potential sources of heterogeneity, including ethnicity and geographical location.

METHODS

Medline was searched up to 31 December 2009 for full articles investigating the prevalence of gr/gr deletions in infertile and control men. A pooled odds ratio (OR) was estimated by a random-effects model. Heterogeneity was assessed by the Cochran's Q test, and quantified by I2 statistic.

RESULTS

A total of 18 case–control studies, including 6388 cases and 6011 controls, met our inclusion criteria and showed that gr/gr deletions were present in 6.86% of cases and 4.69% of controls. The association between gr/gr deletions and infertility was significant (P < 0.001), with a pooled random-effects OR of 1.76 (1.21–2.66) for infertile men versus normozoospermic controls (13 studies). The test for heterogeneity among studies yielded a Q test P = 0.089 with I2 value of 37%, indicating moderate heterogeneity. The association between gr/gr deletions and infertility was dependent on ethnicity and geographic region.

CONCLUSIONS

Our meta-analysis comprising >12 000 men demonstrates that gr/gr deletions occur more frequently in infertile than control men. The association between gr/gr deletions and infertility varies according to ethnicity and geographic region, with an association reaching significance among Caucasian men, in Europe and the Western Pacific region.

Understanding subfertility at a molecular level in the female through the application of nuclear magnetic resonance (NMR) spectroscopy

BACKGROUND

Understanding the aetiology of subfertility and female reproductive tract disorders at a molecular level may improve success rates in fertility treatment. Such understanding may be gained by the application of metabonomics technologies to tissues or biofluids. Metabonomics is concerned with the quantification of molecules in the metabolome and uses nuclear magnetic resonance (NMR) spectroscopy as one of the main technological platforms. This review concentrates on NMR studies of the female reproductive tract and discusses further possible applications. While full metabolic profiling is relatively recent, targeted NMR studies of biofluid and tissue has a longer history.

METHODS

Searches were carried out on MEDLINE®, PubMed, SciFinder® Scholar 2007 and ISI Web of KnowledgeSM for papers about NMR spectroscopy or metabonomics of the female reproductive tract and subfertility.

RESULTS

NMR spectroscopy has been employed for the compositional analysis of various elements of the female reproductive tract, including cervical mucus, follicular fluid (FF), ovarian tissue, fallopian tubes and uterine matter. NMR was used to document for the first time a change in FF lipoprotein concentration during follicular development. NMR analysis of granulosa cells from rats has revealed that follicle-stimulating hormone increases the activity of the pentose pathway, having crucial implications for ovarian stimulation regimens. In the uterine matter work, it has been shown by NMR that glycolysis is rapidly stimulated by estrogen, and in another study, citrate in uterine fluid was found as a potential biomarker for adenomyosis. NMR has also been used to show that chlamydiae are able to achieve higher energy reserves by stimulating glucose transport in host cells.

CONCLUSIONS

A range of NMR spectroscopic techniques have been applied to the analysis of the female reproductive tract, however great potential remains for further studies. Incorporation of metabonomics techniques into female fertility research may be valuable for understanding subfertility and predicting outcomes of assisted conception treatments.

Implantation failure: molecular mechanisms and clinical treatment

BACKGROUND

Implantation is a complex initial step in the establishment of a successful pregnancy. Although embryo quality is an important determinant of implantation, temporally coordinated differentiation of endometrial cells to attain uterine receptivity and a synchronized dialog between maternal and embryonic tissues are crucial. The exact mechanism of implantation failure is still poorly understood.

METHODS

This review summarizes the current knowledge about the proposed mechanisms of implantation failure in gynecological diseases, the evaluation of endometrial receptivity and the treatment methods to improve implantation.

RESULTS

The absence or suppression of molecules essential for endometrial receptivity results in decreased implantation rates in animal models and gynecological diseases, including endometriosis, hydrosalpinx, leiomyoma and polycystic ovarian syndrome. The mechanisms are diverse and include abnormal cytokine and hormonal signaling as well as epigenetic alterations.

CONCLUSIONS

Optimizing endometrial receptivity in fertility treatment will improve success rates. Evaluation of implantation markers may help to predict pregnancy outcome and detect occult implantation deficiency. Treating the underlying gynecological disease with medical or surgical interventions is the optimal current therapy. Manipulating the expression of key endometrial genes with gene or stem cell-based therapies may some day be used to further improve implantation rates.

The different shades of mammalian pluripotent stem cells

BACKGROUND

Pluripotent stem cells have been derived from a variety of sources such as from the inner cell mass of preimplantation embryos, from primordial germ cells, from teratocarcinomas and from male germ cells. The recent development of induced pluripotent stem cells demonstrates that somatic cells can be reprogrammed to a pluripotent state in vitro.

METHODS

This review summarizes our current understanding of the origins of mouse and human pluripotent cells. We pay specific attention to transcriptional and epigenetic regulation in pluripotent cells and germ cells. Furthermore, we discuss developmental aspects in the germline that seem to be of importance for the transition of germ cells towards pluripotency. This review is based on literature from the Pubmed database, using Boolean search statements with relevant keywords on the subject.

RESULTS

There are distinct molecular mechanisms involved in the generation and maintenance of the various pluripotent cell types. Furthermore, there are important similarities and differences between the different categories of pluripotent cells in terms of phenotype and epigenetic modifications. Pluripotent cell lines from various origins differ in growth characteristics, developmental potential, transcriptional activity and epigenetic regulation. Upon derivation, pluripotent stem cells generally acquire new properties, but they often also retain a ‘footprint’ of their tissue of origin.

CONCLUSIONS

In order to further our knowledge of the mechanisms underlying self-renewal and pluripotency, a thorough comparison between different pluripotent stem cell types is required. This will progress the use of stem cells in basic biology, drug discovery and future clinical applications.

Dynamic changes in gene expression during human early embryo development: from fundamental aspects to clinical applications

BACKGROUND

The first week of human embryonic development comprises a series of events that change highly specialized germ cells into undifferentiated human embryonic stem cells (hESCs) that display an extraordinarily broad developmental potential. The understanding of these events is crucial to the improvement of the success rate of in vitro fertilization. With the emergence of new technologies such as Omics, the gene expression profiling of human oocytes, embryos and hESCs has been performed and generated a flood of data related to the molecular signature of early embryo development.

METHODS

In order to understand the complex genetic network that controls the first week of embryo development, we performed a systematic review and study of this issue. We performed a literature search using PubMed and EMBASE to identify all relevant studies published as original articles in English up to March 2010 (n = 165). We also analyzed the transcriptome of human oocytes, embryos and hESCs.

RESULTS

Distinct sets of genes were revealed by comparing the expression profiles of oocytes, embryos on Day 3 and hESCs, which are associated with totipotency, pluripotency and reprogramming properties, respectively. Known components of two signaling pathways (WNT and transforming growth factor-β) were linked to oocyte maturation and early embryonic development.

CONCLUSIONS

Omics analysis provides tools for understanding the molecular mechanisms and signaling pathways controlling early embryonic development. Furthermore, we discuss the clinical relevance of using a non-invasive molecular approach to embryo selection for the single-embryo transfer program.

Therapeutic Approaches to Neurodegeneration – Age Modifiers, Proteostasis, and Stem Cells (Feb. 14-17, 2011, Nassau, Bahamas, United States, North America)

Cliquez pour écouter ce texte Following the success of our 2007 conference on MolecularMechanisms of Neurodegeneration, Andrew Dillin (HowardHughes Medical Institute/Glenn Center for AgingResearch/Salk Institute, USA) will be chairing our nextconference in the series. This year, Dr. Dillin will bejoined by co-chairs David Holtzman (Washington UniversitySchool of Medicine, USA) and Sean Morrison (University ofMichigan, USA).

Understanding Lycopene’s Benefits to Your Heart

A new study from South Korea revealed lycopene’s potential in promoting heart health by protecting the body against damage in the DNA and in enhancing the body’s antioxidant defenses.

A recent study conducted by researchers from South Korea revealed that daily supplementation of about 15 milligrams of lycopene for a period of eight weeks helps lower systolic blood pressure and reduces inflammatory processes related to cardiovascular events while simultaneously increasing the activity of a potent antioxidant that helps to reduce DNA damage that occurs in white blood cells.  The results of the study are found in the Atherosclerosis journal.

Yonsei University, South Korea’s Jong Ho Lee, the study’s lead researcher, along with his colleagues, enrolled 126 healthy men to participate in the study.  The average age was set at 34 and average BMI was at 24 kg/m2.  The participants were then randomly assigned in one of the three groups:  one group received 6 milligrams of lycopene supplements each day for eight weeks, another group was given 15 milligrams of lycopene supplements daily for the same period, while the other group received placebo treatment.

Results showed that SOD (super oxide dismutase) activity rose by 2.37 units/ml in the group that received 15 milligrams lycopene supplements while those who received 6 milligrams lycopene supplements only experienced a 1.73 units/ml increase. The group who receive placebo supplements exhibited decreased SOD activity.  SOD is a potent antioxidant that helps combat oxidative damage brought about by free radical activity.

The Other Health Benefits of Lycopene

Studies have shown the benefits of lycopene consumption especially when it comes to promoting a healthy prostate, heart skin, bones and blood pressure levels.  Because of this, lycopene is now being used in various products such as supplement, beverages and even beauty products. As a matter of fact, according to Mintel’s database of global new products, there were about 500 lycopene-based products that were launched between the year 2003 and 2009.

Aside from the health benefits mentioned above, here are more amazing benefits that lycopene can do for you:

  1. Lycopene is best known for reducing the risk of some types of cancer such as those of the prostate, breast, cervix, and the lungs. Its antioxidant property helps in neutralizing the activity of free radicals which has been tagged as the cause of most diseases that plague the human body.
  2. It can also lessen sun damage to the skin by about 35%.Even just a single cup of tomatoes on a daily basis can already counteract the ill-effects of the free radicals that are given off by the UVB and UVA rays of the sun. If you want to get higher amounts of beneficial lycopene from it, it is advised that you cook the tomatoes first since heat can liberate a greater amount of lycopene from the hard cell membranes of the plant.
  3. It can improve and make your skin look better and it also helps in purifying your blood. This in turn can help in lessening the number of pimples on your face.
  4. Studies have also suggested that regular lycopene consumption can be of great benefit to people with high cholesterol levels, or those with atherosclerosis.
  5. Ongoing studies are also being conducted as to lycopene’s role in the prevention of conditions such as cancers of the urinary tract, stomach, skin, pharynx, pancreas, ovaries, larynx and esophagus.  Others include rheumatoid arthritis, respiratory infection, periodontal diseases, Parkinson’s disease, pancreatitis, melanoma, mesothelioma, diabetes mellitus, cataracts and AIDS.  However, further studies are needed in order to truly establish lycopene’s role in reducing a person’s risk of these conditions.

Sources of Lycopene

Cooking can release lycopene from a lot of plants. But the most popular food sources that you can get a great amount of lycopene from would be ketchup, tomato sauce, tomato paste and the canned tomatoes – more so if it is from the organic kind. Here are some of the other major sources of lycopene aside from the tomatoes:

  • A cup of carrot juice
  • Four asparagus spears, cooked
  • A cup of baked beans
  • Tablespoon of salsa
  • A cup of raw watermelon
  • A cup of marinara sauce
  • A cup of vegetable beef soup

Natural Ways to Ensure a Healthy Heart

Aside from lycopene intake, there are a lot of other ways to ensure a healthy heart.  Your diet, physical activity and lifestyle could influence not just your heart’s health, but your overall health as well.  So I just cannot anymore emphasize the importance of living healthy.  Here are some natural ways which you can easily do to show that you love your heart, and your life:

  • Get sufficient sleep. When you lack sleep, you are most likely to develop high blood pressure.  This is according to the hypertension report published in the Journal of the American Heart Association. Sleep normally allows your heart to take things easy and let your blood pressure drop significantly after a stressful day has passed. Furthermore, sleep gives your body the rest that it needs and allows your body to recover and heal from damage caused by physical, emotional and environmental factors.
  • Eat more vegetables and fruits. Fruits and vegetables play a huge role in supplying your body and heart with considerable amount of vitamins, minerals and important nutrients that can protect your cells from possible damage caused by free radicals which are touted to be one of the major causes of heart failure.
  • Go easy on your coffee intake. Yes, coffee has been said to contain antioxidants but it is also very important that you limit caffeine intake since too much would reverse its effects. Its effects won’t enable you to sleep which, again, is very important to the body.
  • Lessen your salt intake. By doing this, you can cut down the risk of heart disease by 40% according to the studies made by the Department of Health. You must always opt for foods that are low processed and make it to only consume about five to six grams of a salt each day – and make sure it’s organic salt.
  • Get enough folic acid. According to a study published in the Journal of the American Medical Association, sufficient amounts of folic acid within the body helps to maintain healthy blood pressure levels. This, in turn, can also lead to a better heart condition for you to enjoy for the rest of your life.

Sources
nutraingredients.com
hubpages.com
dietbites.com
guardian.co.uk

Discuss this post in Frank Mangano’s forum!

Swedish Study Reveals that Exercise Alleviates Inflammatory Bowel Syndrome

A study conducted by a team of researchers from Sweden found that exercise can help alleviate the symptoms of irritable bowel movement.

IBS or irritable bowel syndrome is a health condition that is commonly associated with diarrhea, constipation, bloating, abdominal pain and frequent cramping in the stomach area. Though IBS does not lead to serious diseases and cause permanent damage to the gastrointestinal tract, the illness results to a great deal of distress and discomfort. Some cases of IBS can easily be managed through prescribed medication, stress management and diet. But some worse cases can be disabling and can, in fact, hinder a person from going to work, travel short distances or attend social events.  According to statistics, approximately 1 out of 5 Americans suffer from IBS; thus, the disorder is considered to be one of the most commonly diagnosed gastrointestinal conditions by medical specialists.

Causes and Symptoms of IBS

The symptoms of IBS can easily be mistaken as symptoms of other digestive disorders. The main symptoms are discomfort, bloating and abdominal pain. But this can differ from person to person. Some people with IBS may experience difficulty eliminating waste, others may have uncontrollable bowel movement and diarrhea, while some people will experience an alternation of diarrhea and constipation. In some cases, the symptoms of IBS can stop for a few months but others may experience continuous and worsening symptoms.

There are a few theories explaining the cause of IBS. One theory explains that the disorder is caused by the colon and large intestine’s sensitivity to stress and certain types of food. There may also be a link between IBS and the immune system. One study conducted to investigate the root cause of IBS found that bacterial infection in the gastrointestinal tract may be causing the disorder. Despite numerous studies, the real cause of IBS is still an open subject.

The Effects of Stress to IBS

Stress, as well as troubled, overwhelmed and angered feelings can result to spasms in the colon area. The colon has numerous nerves that connects to the brain and is controlled by the autonomic nervous system. These nerves are responsible for the normal contraction of the colon when the person suddenly feels stressed and nervous. In IBS cases, the colon becomes over-responsive to stress which then results to the symptoms of the disorder. For people whose IBS triggered by stress, the appropriate treatment is stress reduction, adequate sleep, stress management, and support and counseling.

Traditional Treatment for IBS

Around 70 percent of people with IBS are not getting medical care in order to treat their conditions. People will often resort to over-the-counter medicines which are limited to providing temporary relief. And since the cause of the disorder is yet to be discovered, available treatment for IBS can only deal with the relief of symptoms. Treatments include medication, diet changes and stress management. Medical experts will often suggest dietary modifications such as BRAT for diarrhea (banana, rice, applesauce and toast) and fiber supplementation for cases of constipation.

The Benefits of Exercise to IBS

A study conducted by a team of Swedish researchers found that exercise can significantly help people suffering from irritable bowel syndrome or IBS. The study was conducted primarily at the Alingsas Hospital and the Sahlgrenska University Hospital in Gothenburgm, Sweden. The researchers gathered a group of 102 study participants diagnosed with IBS and divided them into two groups; half of them served as the control group and were asked to maintain their usual lifestyle while the other half was given exercise programs which increased their daily physical activities. The two groups received calls from a licensed physiotherapist to assist them with their condition. Lead researcher, Elisabeth Johannesson, said that the active group was asked to perform moderate to vigorous exercises between three to five times a week for at least 20 to 30 minutes.

At the beginning of the study, the study participants were asked to provide relevant information regarding their IBS conditions including the intensity of the discomfort, stool problems, abdominal pain and quality of life. The same procedures were also conducted at the end of the 3-month study period. Senior physician, Riadh Sadik, was responsible for determining the results of the exercise program. He said that the control group had an average symptom decline of 5 points while the active group experienced a 51-point reduction.

The researchers also reported that only 8 percent of the study group felt worse after following the exercising program. 23 percent of the control group, on the other hand, experienced deteriorating symptoms. Sadik concluded that the slightest increase in a person’s physical activity can significantly help alleviate the symptoms of IBS. The study was published in the American Journal of Gastroenterology.

Natural Ways to Alleviate IBS

IBS can be treated naturally – and this starts by knowing which factors are triggering the disorder. More often than not, IBS is caused by an overly sensitive colon. In this case, stress management and restricted diet can help alleviate the symptoms. To start with, stress management has been the most common approach for IBS patients.

Stress plays a major in triggering IBS and has been found by different studies to be one of the most probable cause of the disorder. Though further studies are still needed in order to better understand the relationship between stress and IBS, researchers had found that symptoms tend to worsen during periods of anxiety. Stress management programs and relaxation exercises can help relieve the symptoms of IBS. People suffering from the disorder can seek the advice of a qualified stress therapist.

A study conducted by a team of researchers from the University of Massachusetts Medical School found that people who practice mindfulness meditation to overcome stress can reduce flatulence by up to 22 percent and improve bloating and diarrhea symptoms.

Dietary change is one of the best ways to relieve the symptoms of IBS. Avoiding certain foods that trigger IBS is the most practical and cost-effective approach to the treatment of IBS. Knowing which food types to avoid will help minimize the occurrence and intensity of the symptoms. Examples of foods to avoid are carbonated beverages, high-fat foods, artificial sweeteners (such as aspartame and sorbitol), fried foods, alcohol, gluten and caffeine.

Eating foods with fiber helps normalize bowel movements. Medical experts say that fiber helps decrease abdominal spasms and push waste out of the body. Foods like fruits, vegetables, whole grains and oats are the best natural sources of fiber.

Sources
digestive.niddk.nih.gov
eurekalert.org
wellbeing-nutrition.com
findarticles.com
quickcare.org

Discuss this post in Frank Mangano’s forum!

Older Obese Individuals can Improve Mobility Through Walking and Weight Loss

A study from the Wake Forrest University found that weight loss and walking can help older obese adults improve their mobility.

Obesity is a common health problem in various societies and demographics. Though the prevalence of the health condition is higher in certain social backgrounds, the number of obese individuals is continuing on an upward trend. Typically, obesity is seen as an accumulation of excess and abnormal amounts of fat in his body. According to the World Health Organization (WHO), a person whose BMI is equal to or more than 30 is considered to be obese. And more than the restricted movements and limited mobility, obesity is also seen as a major risk factor for developing diseases which includes diabetes, atherosclerosis, hypertension, and other chronic illnesses.

In the WHO’s latest global data regarding obesity, approximately 1.6 billion adults are overweight and no more than 400 million are obese. They had also projected that by 2015 the number of obese individuals will grow to around 700 million. These numbers is also projected to directly affect the prevalence of certain health conditions linked to obesity. Years back, surveys proved than obesity is a problem limited to high-income countries. But this changed over the years as the number of obese cases grew in low and middle income countries.

There are various factors that significantly affect a person’s risk of becoming obese. The primary reason is the consumption of disproportionate amount of calories against the person’s calorie expenditure. The bad habits of excessive intake of foods rich in fats and sugars but deficient in minerals, vitamins and micronutrients and the lack of physical activities are causing the problem. And these observations can be seen on a global perspective.

People who are clinically overweight are being found to be at risk of developing certain serious diseases like cardiovascular disease, some types of cancer, musculoskeletal disorders and diabetes. The health problem of obesity is more serious during old age. Obese individuals ages 50 and above are finding it more difficult to manage the condition and are at higher risk of permanent disability and serious health complications resulting to increased mortality rate. But one study found natural ways to help older obese adults better cope with their condition.

Walking and Losing Weight Improves Mobility for Older Obese individuals

A study conducted by a team of researchers from the Wake Forrest University observed that weight loss and walking can improve the mobility of older individuals with obesity and cardiovascular conditions by 20 percent. The study lasted for five years and involved 288 study participants. It is published online on the Archives of Internal Medicine.

The popular belief says that losing weight can be harmful to people at old age. But contrary to this, the researchers found that participating in physical activities and losing weight can be the best means of improving their mobility. According to lead researcher and Professor of Health and Exercise Science, Jack Rajeski, their research is one of the first large scale studies which shows that weight loss can improve the health of older obese individuals with cardiovascular health conditions. This gives health care practitioners more ways to address the needs of senior patients with limited to poor mobility.

Rajeski said that the statistics showing the increasing population of older adults call for a need to find cost-effective community-based lifestyle intervention programs to improve their mobility. In addition to this, they found that 60 percent of the people in this age group are only walking an average of one mile per week. The co-investigators include Michael Perri from the University of Florida, Jacquelyn McClelland and Lucille Bearon from the North Carolina State University, and professor of health and exercise science Peter Brubaker, Walter Ambrosius and Dr David Goff of Wake University. Rajeski added that a community-based preventive lifestyle intervention is very important.

The team of researchers partnered with three health care professionals and with the North Carolina Cooperative Extension to effectively conduct the study and gather reliable results. The study participants aged 60 to 79 were tracked over a period of 18 months and were divided into three groups. The control group was educated on successful aging, the other was asked to participate in physical activities and weight loss programs while the third group was limited to physical training.

The results from the group subjected to physical training showed significant effects but researchers found that the combination of weight loss and physical activity produced more notable results. The study participants exhibited improved mobility by 5 percent, while those who had limited mobility improved by around 20 percent. To observe their improvements, the participants were asked to take a 400-meter walk; this is a widely used method of measuring the mobility of senior individuals. The researchers said that prevention is very important for older people who are starting to lose their mobility since the symptoms can be progressive and often result to permanent disability.

Rajeski concluded that a person’s ability to walk without any assistance is vital in improving a person’s capacity to function better in the community. He added that the next step will be to establish a model that can be replicated at different areas in the United States and that they will be working with other institutions in the state to achieve this goal.

Natural Ways to prevent Obesity

Obesity is highly preventable. Though some researchers had found that some people are more genetically inclined to the development of the health condition, natural methods can be implemented in order to lower the risk.

The essential step is to maintain energy balance and participate in more physical activities. A person’s energy intake needs to appropriately respond to the person’s physical activities without taking his nutritional needs for granted. Foods rich in harmful fats needs to be avoided, while the consumption of fruits and vegetables as well as whole grains, legumes and nuts needs to be increased as these are energy-giving foods. The recommended physical activity is a minimum of 30 minutes of exercise in most days of the week. The initiative of maintaining a healthy weight needs to come from the individual and this needs to be for the purpose of promoting better health and preventing the onset of health conditions including obesity.

Sources
eurekalert.org
who.int
who.int

Calcium and Vitamin D Supplementation Helps Prevent Osteoporosis

A study conducted by a team of Australian researchers found that the increased supplementation of vitamin D and calcium can result to a significant increase in bone density and reduction in osteoporosis risk.

There are approximately 75 million people who suffer from the health condition in Japan, Europe and the United States. And according to statistics, women are four times more likely to develop the health condition than men.

A study conducted by a group of Australia researchers found that the supplementation of 400 IU of vitamin D3 and 800 milligrams of calcium can notably increase the bone strength and density of peripubertal female identical twins. The study was published in Osteoporosis International, a publication dedicated to discussing the issues on osteoporosis. The health condition is characterized by low bone density resulting to an increased risk of bone fracture and deformation of the wrist, spine and hip area.

The traditional approach in preventing osteoporosis aims to increase the person’s bone mass. And this can be achieved though calcium and vitamin D supplementation at pubescent years and in pre-menopausal age where the osteoporosis risk is noted to be higher. The bone build-up during the puberty years accounts to around 35 percent of a person’s adult bone mass.

Vitamin D and Calcium:  Effects on Osteoporosis

The researchers from the Australian Catholic University gathered a group of 20 identical twins and divided them into two groups. The first group was given a combination of vitamin D and calcium food supplement while the other served as the placebo group. The study lasted for six months and was the first to use pQCT, or peripheral quantitative computed tomography, to examine and measure the responses of the study participants’ bone structure. They found that the combination of vitamin D and calcium resulted to an increase in the study participants’ bone strength and bone density in the arm and shinbone by 4 to 66 percent depending on the specific bone area tested.

Earlier studies had already provided scientific evidence that calcium and vitamin D intake improves bone density and strength. A randomized trial conducted by a team of scientists from the University of Sheffield in the UK, for example, found similar results. The study was published in the February issue of the American Journal of Clinical Nutrition. In the study, the researchers observed that the supplementation of 792 milligrams of calcium resulted to an increase in the study participants’ bone mineral content and bone density. They also observed that the effects were reversed once the supplementation stopped.

The annual sales for calcium food supplements was about $993 million in 2004 according to the information provided by the Nutrition Business Journal. And this is projected to increase to $22 billion by 2013 according to the survey conducted by the Ipsos Public Affairs for the Council of Responsible Nutrition.

The Relationship between Calcium and Vitamin D

Calcium is an essential nutrient needed for the essential function of the nerves, muscles and the heart. The inadequate supply of calcium in the body often results to the development of osteoporosis. Studies show that the lack of calcium intake in early life can result to low bone density and increased bone fracture rate in adulthood. National surveys, however, found that people are not satisfying their daily calcium recommendation to promote and maintain bone health.

The recommended calcium intake for children and young adults aged 9 to 18 years is 1300 milligrams.  This is according to the National Academy of Science. In order to ensure that the risk of developing osteoporosis is decreased, it is important therefore, that one’s daily calcium intake is in accordance with the recommended intake. However, simply eating foods rich in calcium and taking calcium supplements is not enough. The body needs the help of precursors to promote calcium absorption so that it can be effectively utilized by the body. The active form of vitamin D is calcitriol. The substance is responsible for calcium absorption and the storage of calcium in the bones.

There are three ways a person can satisfy his vitamin D needs: these are through the skin, from supplementation and from diet. Vitamin D can be produced by exposing the body to sunlight. Exposure to the sun without any protection for a minimum of 15 minutes in a few days a week can give the body enough vitamin D to function properly. Medical experts also suggest a minimum of 400 to 600 IU of vitamin D a day from food and food supplements to promote better calcium absorption. The richest natural sources of vitamin D are liver, saltwater fish and egg yolks.

Natural Ways to Prevent Osteoporosis

Increasing the intake of vitamin D and calcium is the first step to reducing the risk of developing osteoporosis. The second step is to exercise regularly. Studies found that regular exercise, together with increased calcium and vitamin D consumption, can significantly reduce a person’s osteoporosis risk. Weight training can improve a person’s metabolism, tone the muscles and helps in maintaining health and strong bones. It is not important what kind of exercise a person does. But what is important is its frequency, intensity and consistency. Aerobics and weight training for a minimum of thirty minutes will make the bones stronger. Stair climbing, hiking, jogging and even dancing can produce enough movements keep the bones healthy and strong.

Eating foods rich in essential fatty acids is essential in keeping the intestinal lining healthy and more capable of absorbing minerals from the foods we eat. Vitamin A promotes better absorption of minerals like magnesium and calcium while antioxidants from natural sources helps reduce the risk of developing osteoporosis by protecting the bones from the damage caused by free radicals. Fruits and vegetables can also improve bone density by supplying the body with potassium and magnesium.

Get into the habit of having your bone density regularly checked. This is an important preventive measure to avoid the onset of osteoporosis. Bone density test will evaluate your osteoporosis risk and give you recommendations of whether you need to get more supplementation of vitamin D and calcium. Note that osteoporosis can remain undetected for years until you experience obvious symptoms like serious bone fracture and bone deformation. This makes early diagnosis very important.

Sources
nutraingredients.com
ncbi.nlm.nih.gov
jacn.org
nutraceuticalsworld.com
niams.nih.gov

Nitrate in Spinach May Help Improve Cell Function

A study published in an issue of Cell Metabolism revealed that researchers found that the consumption of spinach can increase the performance of the power house of the cells, the mitochondria.

A team of researchers observed how doses of inorganic nitrate can improve a person’s muscle performance. They gathered a group of healthy people and asked them to take in specific amounts of inorganic nitrate.  This lasted for a period of three days and researchers then observed how their oxygen consumption responded to the change in diet. The results of the study were published in the science journal Cell Metabolism. But despite the promising results, the researchers said that they are not recommending the intake of inorganic nitrate food supplements basing on the results of their study alone. They added that they are recommending the consumption of natural sources like green vegetables and fruits to obtain the health benefit of nitrate.

Head researcher from the Karolinska Institutet in Sweden, Eddie Weitzberg, said that the dosage of nitrate which they used in the study is equivalent to that contained in a small spinach plate and three red beets. He added that the consumption of more vegetables and fruits can help reduce the risk of developing diabetes and cardiovascular disease. But it is unclear which nutrients in these natural food sources are responsible for producing the effects. The researchers are looking at inorganic nitrate as one of the strongest candidate.

Nitrate: Under the Magnifying Glass

The nutritional value of nitrate is not well established compared to other well-studied nutrients. Other people are considering nitrate as a toxic substance that may produce adverse effects to the body in high amounts. But the researchers found that nitrate can be beneficial to the body by acting as a co-producer of nitric oxide assisted by good bacteria present in the mouth. Nitric oxide had been found by decades of scientific research to be beneficial in opening up the blood vessels, lower blood pressure and reduce the risk of cardiovascular disease.

The Swedish researchers found another health advantage of nitrate and its resulting nitric oxide. The mitochondria is responsible for providing power to the cells. But levels of protein decreases in the process of increasing its efficiency which in turn makes the mitochondria become leaky. Weitzberg said that the mitochondria is not fully efficient in normal circumstances and added that no machine is.

The study showed that the increase intake of nitrate through diet can have an immediate effect to the body by increasing the efficiency of the mitochondria. But researchers are still finding a way to determine the long term effects of eating inorganic nitrate to people. Weitzberg said that their next study will focus on observing the effects of inorganic nitrate to people with health conditions concerning the mitochondria like mitochondrial dysfunction, cardiovascular disease and diabetes.

The researchers concluded that other studies had been consistent in saying that eating fruits and vegetables can have positive effects to the body like the prevention of certain diseases like diabetes and cardiovascular disease. But despite this, they added that the mechanisms responsible for producing these effects are still not for certain. Weitzberg also said that certain organisms in the mouth need to be present in order to fully take advantage of the health benefits of nitrate; the use of strong mouthwashes can kill these microorganisms and may prevent the production of the nitric oxide in the body.

Health Benefits of Eating Spinach

Spinach is an epic vegetable with tons of health benefits but which is dreaded by most kids. It has more nutrients than any other vegetable and is very available throughout the year; but it has the best flavor during its season which runs from September to October. The vegetable belongs to the family of beets and Swiss chard and has a similar taste with the other vegetables in its group. Spinach has a distinctive mild and sweet taste which makes it perfect for making salads, but the taste becomes more robust and acidic once cooked. The three types of Spinach available in the market are baby spinach ideal for salads, smooth-leaf and savoy.

The Anti-Cancer and Anti-Inflammatory Health Benefits of Spinach

Studies had found that spinach has more flavonoid content than other vegetables. Researchers had identified more than a dozen favonoids in spinach which are effective in reducing cellular inflammation and the risk of developing certain types of cancer. The evidences indicating that the potential antioxidant value of spinach is strong enough for research to extract these compounds for controlled laboratory studies. And they found that the compounds are effective in reducing the cell division rate of human stomach cancer cells.

Studies using laboratory animals also showed that the extracts can inhibit the growth of skin pappilomas or skin cancer cells. In addition, a related study found that women with higher intake of spinach have lower risk and incidence of breast cancer than women who ate less of the jade green vegetable.

Spinach is also a good source of carotenoids and other antioxidants like vitamin E, beta-carotene, manganese, vitamin C and zinc that have been found to inhibit inflammation and reduce cancer risk. The peptides in spinach can also lower blood pressure and help in treating and lowering the risk of certain diseases like atherosclerosis and other blood-vessel related problems.

Two other important and powerful antioxidants can also be found in spinach. These are zeaxanthin and lutein which can naturally be found in certain areas of the eye like the macula and retina. Though there hasn’t been any large scale study which investigated the effects of lutein and zeaxanthin in preventing eye problems like macular degeneration, studies have found that the consumption of spinach can increase the concentration of lutein in the blood.

Spinach for Bone Health

A cup of boiled spinach contains around 100 percent more of the body’s daily requirement of vitamin K; this nutrient is essential in preventing the excessive activation of osteoclasts which are responsible for breaking down the bones. In addition to this, vitamin K reacts with certain microorganisms in the stomach to produce vitamin K2 which is an important component in the production of more osteocalcin in the bones. Osteocalcin helps in storing more calcium in the bones to make it stronger. There’s a reason why Popeye always had a can of spinach with him.

Sources
eurekalert.org
whfoods.com
spinachwords.com
buzzle.com

Discuss this post in Frank Mangano’s forum!

Cherry Juice and What You Can Do to Hasten Exercise Recovery

A study conducted by a team of researchers from London found that drinking cherry juice rich in polyphenols can boost recovery after exercise.

The body experiences a series of interconnected metabolic processes during exercise. You will begin to notice heavier and faster breathing, faster heart rate and your muscles will begin to heat up and feel sore. This is the body’s natural response to mild and extreme physical activities, and this can intensify to higher levels depending on the intensity of the physical activity. Exercise demands different systems in the body to respond according to the increased demand for energy. Body heat, breathing and blood circulation will be affected.

Different forms of exercise call for the action of specific muscle groups. Other more strenuous forms of exercise may require the use of multiple muscle groups. But in any case, exercise means muscle activity. The muscles will demand other systems in the body to respond and produce energy. Each system in the body will either work more, work less or focus on muscle activity. The heart, for example will start beating faster to speed up the circulation of blood and energy throughout the body while the stomach temporarily slows down in digesting food in order to channel more energy into the muscles.

Adenosine triphosphate, or ATP, is an essential biochemical fuel needed by the body to supply the muscles with energy. ATP needs to be burned in order for it to be transformed into usable energy. And this process will require oxygen, the elimination of metabolic wastes like lactic acid and carbon dioxide which are produced in the process, and the omission of heat out of the body.

After about 30 minutes to an hour of exercise, the body is tired and exhausted. And recovery is needed before doing the same routine all over again. The body will need at least 24 to 48 hours of recovery for muscle and tissue repair, especially when weight lifting. There are natural techniques to hasten and improve recovery after performing an exercise. A study conducted by a team of researchers from London found that the simple habit of drinking cherry juice can help the muscles recover faster.

Cherry Juice for Faster and Better Recovery

Researchers from London found that cherry juice can boost the muscle recovery after strenuous exercise. Previous studies had reported that the antioxidants in cherries can help the body overcome the oxidative damage caused by exercise. The study, conducted from the London South Bank University Sports and Exercise Science Research Center, focused and looked at the antioxidant property of cherry juice and its potential in hastening muscle recovery.

The study was published in the Medicine and Science in Sports Exercise. The researchers observed that people who were subjected to a week of drinking a certain branded cherry juice after a series of intensive exercise routines can help speed up recovery time and create better results compared to those who consumed control beverage. The cherry juice used in the study was from Montmerency beverage company. Lead researcher, Dr Joanna Bowtell, said that Montmorency cherry juice can improve the recovery of isometric muscles after exercise due to its strong antioxidant property.

A related study published in the Journal of Nutrition reported that the consumption of at least 45 cherries in a day can reduce the circulation of inflammatory markers in the body. This is due to the anthocyanin and flavonoid content of cherries, the researchers said. Reducing the amount of inflammatory compounds in the body can help reduce the muscle damage caused by exercise and lessen recovery time.

The researchers gathered a group of 10 competitive weight lifters to participate in the study and divided them in half. The first group was asked to drink cherry juice 7 days before and 2 weeks after a series of single leg knee extensions. The second group was subjected to the same process but with fruit concentrate in place of the cherry juice. At the end of the study, the researchers found that the recovery of the first group was faster than that of the control group but there was no noticeable difference between their energy production.

The industry of food nutrition in North America costs around $3.2 billion while Western Europe accounts for $713.6 billion of the industry. Researchers and sports scientists are continuously on the lookout for better ways of improving the performance of athletes by creating new exercise programs and products that promote better and faster recovery. But for individuals who simply want to improve their performance and enjoy a healthy life, there are several natural ways of hastening recovery time without spending too much.

Natural Ways to Speed Up Recovery after Exercise

The body needs time to recover. The length of time needed for the muscles to repair may vary depending on the intensity of the exercise. Resting between exercise days will not only let the body perform its natural recovery process but this will also help avoid injuries in the future. So make it a point to get enough sleep and sufficient nutrition after each exercise.

Stretching is not only needed before doing any form of physical activity, but stretching after each exercise can also help the muscles recover faster. Moving around or maintaining the same exercise but at a lower intensity for a few minutes will help remove lactic acid from the body. Lactic acid substances are produced in the combustion of ATP and may result to muscle stiffness.

Get enough nutrients from the food you eat and replace lost fluids. During exercise, the body makes use of available and stored energy. Refueling by eating the right kinds of food will help the body recover better and faster. Drinking a lot of fluids during and after exercise is also recommended to avoid dehydration, promote the flow of nutrients and support certain metabolic processes.

Taking an alternation of cold and hot baths a few hours after heavy exercise will help in alleviating muscle soreness and prevent injury. Contrast water therapy will help get rid of waste products faster by repeatedly dilating and constricting the blood vessels. Some athletes alternate 30 seconds of cold water with 2 minutes of hot water for four times with a short rest in between.

The key to faster recovery is using an exercise routine that allows time for recovery. Over-training without sufficient rest may only defeat the purpose of exercising.

Sources
nutraingredients.com
sportsmedicine.about.com
health.howstuffworks.com

Discuss this post in Frank Mangano’s forum!

Cocoa: What It Does to the Heart

Cocoa is famous for its numerous health benefits, and one study gives us another reason to reach for that dark chocolate and give in.

A lot of people are in love with chocolates – and there is really nothing wrong with this, as long as the right kind of chocolate is consumed.  Dark chocolate is definitely way better than milk chocolate.  Aside from the health benefits provided by its rich cocoa content, it does not contain the same amount of sugar as the milk chocolate.  So the next time you feel the temptation to eat chocolate, give in – as long as it is of the dark kind. Remember this:  the darker the chocolate is, the higher is its cocoa content.

Recently, a group of researchers coming from Meiji Seika Kaisha’s Food and Health R&D Laboratories released the results of a study that they conducted regarding the effects of cocoa towards the promotion of a healthy heart.  The Japanese company’s researchers revealed that cocoa’s capability to potentially increase the levels of high density lipoprotein, or the good form of cholesterol, is linked to the presence of a protein that can enhance apolipoprotein A1 levels.  Also known as Apo-A1, apolipoprotein A1 is a compound that is needed for the body’s production of HDL cholesterol.

The researchers wrote in the Journal of Agricultural and Food Chemistry that polyphenols present in cacao may be responsible for acting on pathways that are responsible for the metabolism of cholesterol.  They looked at the human intestinal cell effects of polyphenols found in cacao such as procyanidin, catechin, and epicatechin.  Results have shown that these polyphenols raised the protein levels of Apo-A1 while simultaneously lowering alipoprotein B levels which carries LDL cholesterol to the cells.

The Health Benefits of Cocoa

Aside from its polyphenol contents, the health benefits of cocoa are also taken from its component called flavonoids, which serve as major antioxidants to prevent any possible damage to the cellular system.  Free radicals bring about oxidative damage inside the body which could be factors in the development of chronic diseases like heart failure and cancer. The powder of cocoa can also help in lowering blood pressure and improving the blood circulation of every individual. Compared to green tea, just one cup of cocoa has about three times the antioxidants that a cup of green tea has.

Numerous health experts believe that cocoa can only work to your advantage if you would take it in quantities that are just enough. Overconsumption, of course, has its drawbacks.  When choosing a cocoa formulation, go for something that contains the least amount of cocoa.  There are a lot of cocoa powders that are available in the market today which contains various additives such as hydrogenated oils and corn syrup that are high in fructose. Hence, choose to consume the unprocessed type of cocoa powder.

Researchers from Cornell University said that the most ideal way of taking full advantage of cocoa benefits is through drinking. Taking in a cup of hot cocoa every once in a while can work as a great antioxidant just like wine and tea. It can also help steer one away from the impairment of the immune system and other inflammatory processes.

Show Some Love to Your Heart

To live with a healthy heart requires a lot more than just having a healthy diet. It also includes regular exercise and an overall healthy lifestyle. Here a few tips on how to ensure that your heart remains healthy all the time:

  • Limit your consumption of foods that have lots of trans-fat.  These are usually found in fried foods and margarine.
  • If you have a sweet tooth, then you must also limit your sugar intake. High amounts of glucose in the blood could lead to the development of diabetes, and this interferes with blood viscosity.  A blood that is too viscous would cause problems in circulation and other organs of the body will not have their fare share of blood.  Because of this, the heart has to pump doubly hard to ensure that blood is supplied to all organs.  Overworking the heart could lead to its enlargement (cardiomegaly), or worse, heart failure.
  • Only utilize extra virgin olive oil and add some garlic when you cook to help in lowering your cholesterol along with adding some Omega 3 fatty acids.
  • Exercise for about 3 to 4 times a week and then stick to this routine.  Lifting weights is not required but doing cardiovascular, or aerobic, exercises can work wonders to your heart.  So set some time each day where you can perform exercises that you are capable of doing. What is important is that you have the desire to start incorporating changes in your lifestyle, one step at a time. Remember to stay hydrated too and warm up before each exercise session.
  • To add up to your healthy diet and exercise, try your best to steer away from any kind of vices like smoking and drinking too much alcoholic beverages.
  • Manage your stress levels and implement ways to cope.  Attend a yoga class, meditate each day or just simple do deep breathing exercises.  Take time to rest, get lots of sleep since this will help your body heal.
  • Watch out for your weight too since obesity is one of the primary causes of heart disease.
  • If your cholesterol level is high then you can naturally lower it by using several herbal extracts along with fish oil. It could help for you to know that 20% of your cholesterol level is sourced from the foods you consume while the rest of the 80% is produced by your liver. If your fat levels are high, then you must go easy on your carbohydrate and sugar consumption. To lower this, you can take in fish oil, some sufficient amount of vitamin C and even green tea.

Your heart’s health, and your general health as well, is in your hands – and the first step is to make the decision to start living healthy.  Each of your action and decision affects you, and the people around you, so nothing is really too small.  You see, even your choice of chocolate has the potential to affect your longevity.

Sources
nutraingredients.com
naturalhealthezine.com
healthy-heart-guide.com
womenfitness.net

Discuss this post in Frank Mangano’s forum!

Fruits and Vegetables Help Reduce Ischemic Heart Disease Risk

A new study discovered that regular consumption of fruits and vegetables greatly helps in reducing the risk of Ischemic Heart Disease.

Nowadays, more and more people are suffering from coronary artery diseases, also medically known as Ischemic Heart Disease (IHD). Ischemia happens when blood is restricted from entering a specific area, which causes the structures in that area to necrose, or to die, since blood carries with it life-giving oxygen and other essential nutrients. In the case of ischemic heart disease, blood supply is restricted from entering the heart.  Because of this, problems start to arise.

The development of Ischemic Heart Disease is dependent on the health of the blood vessels.  Arteries, for example, are the main sites for fatty plaque build-up.  When a person’s bad cholesterol level is too high, this would result to the accumulation of fatty deposits in the linings and the walls of the arteries.  Over time, this build-up will impede blood supply which will result to ischemia.  This is the main reason why health professionals have always emphasized the need to consume a healthy diet. Other risk factors for the development of IHD includes a family history of the said disease; when there is too much fat content in your daily diet; smoking; hypertension, and even the occurrence of a previous stroke or heart attack.

In the United States today, heart disease is the primary cause of death amongst the entire population. The primary cause of this ailment remains unknown but the number of risk factors is considerably high. It has been clear lately that the treatment of abnormalities of the body’s lipids can delay the progress of a possible atherosclerosis.

There are particular tests that can be done to know how much your ischemic heart disease has grown. Several diagnostic tests include electrocardiogram, echocardiogram, blood studies, x-rays, coronary angiogram and many more.

Eat More Fruits and Veggies

A recent study done in Europe investigated the relationship between the disease and diet and found out that those who get to eat a larger amount of vegetables and fruits seem to have a lower risk of suffering from ischemic heart disease. The said study was published online last January 19 at the European Heart Journal.

Their data showed that those who take in at least eight servings of vegetables and fruits everyday had about 22% lower risk of dying from Ischemic Heart Disease or IHD compared to those who eat less, or just about three servings a day. The lead author of the study, Dr. Francesca Crowe, stated that their research included more than 300,000 people from 8 different countries all around Europe.

According to Dr. Crowe, the bottom line of their analysis only says that if people would consume greater amounts of vegetables and fruits, then this would lead to a reduction in the number of IHD cases. However, she emphasizes that it is still important for individuals to live a healthy lifestyle by exercising and avoiding unhealthy habits such as smoking, substance abuse and drinking to the point of intoxication.

Natural Ways to Prevent Ischemic Heart Disease

Ischemic heart disease is considered to be a silent killer.  Sometimes, you go through life not knowing anything and when it hits you, it takes you aback. It is important, therefore, that you take note of these general measures that can help you prevent them from happening. The following are some of the most important ways that you can fight IHD, or any form of disease for that matter:

  • Get Some Regular Exercise. Exercise can help a lot in improving your blood flow and even reduce the occurrence of abnormal heart rates. This can include simple changes in your routine like probably taking the stairs instead of getting on the elevator, or walking the four blocks to your favorite library instead of taking the cab. But of course, it is much better if you can commit to doing regular exercise that you would already consider as a habit like probably walking or jogging a few minutes every other day.
  • Maintain A Healthy Diet. It is really very crucial that you watch what you eat when you are trying to monitor your cholesterol levels. You must be able to reduce it to a certain amount that would reach normalcy. Eat foods that are low in cholesterol and fats. It is also very important that you remember staying away from fats that are saturated. Your diet must include a lot of fruits and vegetables so that maintaining your ideal body weight would be less of a hassle.
  • Live a Healthy Lifestyle. As much as possible, try to avoid smoking and avoid, or limit, your alcohol intake. It is very essential for you to always get to monitor your blood pressure and always keep things in control. Try to be happy all the time so that you will not be prone to heart attacks due to too much stress. If you are currently overweight, then it is about time to start thinking about lowering your total weight and bringing it back to normal.
  • Talk to your Doctor. If you are overly worried with your heart’s condition, especially when you realize that you are not growing any younger, then you must not put off having regular check-ups with your doctor. It would not hurt that much if you would take the time to see him on a regular basis. These visits could include some tests or examinations that would try to figure out any possible threats to your heart and the rest of your body. Early diagnosis and treatment of Ischemic Heart Disease can definitely lead to total recovery. Through the years, lots of research has been done to promote and encourage fast and effective treatments for this ailment. It is very essential that you maintain a healthy lifestyle especially when it comes to making certain important changes in your diet and level of activity.

Remember this: a failure of the heart to function will lead to the loss of function of the other organs as well.  A deteriorating heart will cause a cascade of events which can sometimes prove to be fatal.  So if you love the people around you, do them a favor by loving your heart first – and then all else will follow.

Sources
eurekalert.org
rxmed.com
populararticles.com
mayoclinic.com

Discuss this post in Frank Mangano’s forum!