Alice Walker on being nurturing as a grandparent to all children.
Monthly Archives: April 2010
Prevention of Acupuncture Infection Needs More Focus
(HealthDay News) -- More needs to be done to prevent a rising tide of infections related to acupuncture, researchers from the University of Hong Kong say.
In a commentary, published online March 19 in BMJ, Patrick Woo and his colleagues stressed that "to prevent infections transmitted by acupuncture, infection control measures should be implemented, such as use of disposable needles, skin disinfection procedures, and aseptic techniques. Stricter regulation and accreditation requirements are also needed."
Five percent to 10 percent of acupuncture patients who develop certain kinds of bacterial infections go on to experience serious complications, the authors pointed out. These can include joint deterioration, flesh-eating disease and even paralysis and organ failure. Read more...
Kama Yogi for Optimal Male Sexual Performance!
An Interview With the Departing Sirtris CEO
An interesting article: "In what turned out to be his final official engagement as CEO of Sirtris Pharmaceuticals, Christoph Westphal offered some key lessons in how to build a successful biotech company ... It's pretty amazing ... in the last 20 years, we've gone from zero understanding of the genes that play a role in aging to a pretty clear understanding that IGF1 plays a role, MTOR, the Sirtuins play a role, there's 10-15 genes play a role. Many of those are going to be druggable targets. Will Sirtris be successful? I don't know. It's still going to be very risky. But I'll be shocked if there are not drugs in the next 10-15 years that target genes that control aging. ... Westphal did not shirk from addressing the ongoing controversy surrounding the physiological activity of some Sirtris compounds. ... There's a debate in the academic world. We don't know the specific molecular mechanism of why you need a specific substrate on the in vitro screen to find Sirt1 activators. ... It's a numbers game and it's gotten harder with the FDA ... People are spending less on pharma R&D and more on consumer health care and trying to diversify into developing countries and away from Europe and the United States. Fewer drugs are getting approved, revenues are going down, margins are going to go down."
View the Article Under Discussion: http://www.bio-itworld.com/news/04/26/10/Christoph-Westphal-on-aging-pharmageddon.html
Read More Longevity Meme Commentary: http://www.longevitymeme.org/news/
One of Many Oddities in Aging and Longevity
Scientists proceed in their work by discovering a correlation and then picking apart the underlying mechanisms to find out why the correlation exists. In the field of aging research a great many as yet unexplained correlations exist, any one of which may point the way to important new knowledge. Take this for example: "Biological rhythms that oscillate with periods close to 24 h (circadian cycles) are pervasive features of mammalian physiology, facilitating entrainment to the 24 h cycle generated by the rotation of the Earth. In the absence of environmental time cues, circadian rhythms default to their endogenous period called tau, or the free-running period. This sustained circadian rhythmicity in constant conditions has been reported across the animal kingdom, a ubiquity that could imply that innate rhythmicity confers an adaptive advantage. In this study, we found that the deviation of tau from 24 h was inversely related to the lifespan in laboratory mouse strains, and in other rodent and primate species. These findings support the hypothesis that misalignment of endogenous rhythms and 24 h environmental cycles may be associated with a physiological cost that has an effect on longevity."
View the Article Under Discussion: http://pmid.us/20392719
Read More Longevity Meme Commentary: http://www.longevitymeme.org/news/
"The doctor in literature: Private life" by Solomon Posen at Google Books
"This is a structured, annotated and indexed anthology dealing with the personality and the behaviour of doctors, and doctor-patient relationships - ideal for medical humanities courses."
Posted at Clinical Cases and Images. Stay updated and subscribe, follow us on Twitter and connect on Facebook.
Medical school letters of recommendation have formally been replaced by tweets
If you are a medical school I highly suggest you admit @beccacamp .@LeeAase I don't know if Mayo School of Medicine takes Twitter recommendations but I formally recommend @beccacamp. Medical school letters of recommendation have formally been replaced by tweets.
Posted at Clinical Cases and Images. Stay updated and subscribe, follow us on Twitter and connect on Facebook.
Ventricle Vase
This gorgeous vase, designed by Eva Milinkovic of Ontario-based Tsunami Glassworks, does a wonderful job of representing the beauty and flux of emotion attributed to the heart. Eva is actually the creative director of Tsunami Glassworks and imbues each piece she does with her passion for “bright colors, organic, fluid forms and tactile objects.”
[thanks to everyone who submitted this beautiful piece!]
"Excellent Old-School Science Models," Life Magazine Photo Gallery
The images you see above--and the captions below--are drawn from a really fantastic Life Magazine online photo gallery entitled "Excellent Old-School Science Models." You can see the entire gallery of 29 images--well worth your perusal!--by clicking here.
Captions top to bottom, as supplied by the gallery:
- Isn't She Lovely: Trainee nurses examine a model of a human body to learn anatomy, Gerry Cranham, Oct. 7, 1938
- Behind It All: A technician works on life-like models for use in science and health lectures at the Cologne Health Museum in Germany, Ralph Crane, Feb 01, 1955
- Going Deep: A technician at the Cologne Health Museum gets into his work, Ralph Crane, Feb 01, 1955
- The Egg Factory: An exhibit illustrates the biology of the chicken at the World Poultry Exhibition at the Crystal Palace exhibition hall in London, Fox Photos, Jul 28, 1930
- Universal: A girl scout leans in to take a closer look at an enclosed model of the solar system, circa 1920s, George Eastman House, Jan 01, 1920
Found via Morbid Anatomy Library intern Amber Duntley's Facebook feed. Thanks, Amber!
Production of ethanol from winter barley by the EDGE (enhanced dry grind enzymatic) process
Background:
US legislation requires the use of advanced biofuels to be made from non-food feedstocks. However, commercialization of lignocellulosic ethanol technology is more complex than expected and is therefore running behind schedule. This is creating a demand for non-food, but more easily converted, starch-based feedstocks other than corn that can fill the gap until the second generation technologies are commercially viable. Winter barley is such a feedstock but its mash has very high viscosity due to its high content of -glucans. This fact, along with a lower starch content than corn, makes ethanol production at the commercial scale a real challenge.
Results:
A new fermentation process for ethanol production from Thoroughbred, a winter barley variety with a high starch content, was developed. The new process was designated the EDGE (enhanced dry grind enzymatic) process. In this process, in addition to the normal starch-converting enzymes, two accessory enzymes were used to solve the beta-glucan problem. First, beta-glucanases were used to hydrolyze the beta-glucans to oligomeric fractions, thus significantly reducing the viscosity to allow good mixing for the distribution of the yeast and nutrients. Next, beta-glucosidase was used to complete the beta-glucan hydrolysis and to generate glucose, which was subsequently fermented in order to produce additional ethanol. While beta-glucanases have been previously used to improve barley ethanol production by lowering viscosity, this is the first full report on the benefits of adding beta-glucosidases to increase the ethanol yield.
Conclusions:
In the EDGE process, 30% of total dry solids could be used to produce 15% v/v ethanol. Under optimum conditions an ethanol yield of 402 L/MT (dry basis) or 2.17 gallons/53 lb bushel of barley with 15% moisture was achieved. The distillers dried grains with solubles (DDGS) co-product had extremely low beta-glucan (below 0.2%) making it suitable for use in both ruminant and mono-gastric animal feeds.
Periodic mass-loss episodes due to an oscillation mode with variable amplitude in the hot supergiant HD?50064***
Authors: C. Aerts, K. Lefever, A. Baglin, P. Degroote, R. Oreiro, M. Vu?kovi?, K. Smolders, B. Acke, T. Verhoelst, M. Desmet, M. Godart, A. Noels, M.-A. Dupret, M. Auvergne, F. Baudin, C. Catala, E. Michel and R. Samadi.<br />Astronomy and Astrophysics Vol. 513 , page L11<br />Published online: 29/04/2010<br />
Keywords:
asteroseismology ; stars: oscillations ; stars: winds, outflows ; stars: individual: HD 50064 ; stars: atmospheres ;
supergiants .
Confirmation of the occurrence of the Hall instability in the non-linear regime
Authors: J. A. Pons and U. Geppert.<br />Astronomy and Astrophysics Vol. 513 , page L12<br />Published online: 29/04/2010<br />
Keywords:
magnetohydrodynamics (MHD) ; stars: neutron ; stars: magnetic field ; stars: evolution .
XMMU?J100750.5+125818: a strong lensing cluster at z = 1.082 ******
Authors: A. D. Schwope, G. Lamer, A. de Hoon, J. Kohnert, H. Böhringer, J. P. Dietrich, R. Fassbender, J. Mohr, M. Mühlegger, D. Pierini, G. W. Pratt, H. Quintana, P. Rosati, J. Santos and R. Šuhada.<br />Astronomy and Astrophysics Vol. 513 , page L10<br />Published online: 29/04/2010<br />
Keywords:
galaxies: clusters: individual: XMMU?J100750.5+125818 ; X-rays: galaxies: clusters .
Evidence of enhanced formation episodes in the Galactic open cluster system
Authors: A. E. Piatti.<br />Astronomy and Astrophysics Vol. 513 , page L13<br />Published online: 29/04/2010<br />
Keywords:
galaxies: star clusters: general ; open clusters and associations: general.
What’s Cassini Up To?
Have you been keeping up with Cassini? Today (April 27th Pacific and April 28th UTC) it’s scheduled to make a flyby of Enceladus, passing as close as 60 miles above the surface of the moon. According to the mission counter, the closest point in the flyby will be at about 7pm CDT, April 27th – United States.
Cassini will fly through the water-rich plumes over the moon’s south polar region. In addition, Cassini scientists will be conducting gravity studies on this flyby which will help determine what lies beneath the ice crust on the surface of Enceladus.
All the data we have up to this point indicates there is an ocean of liquid water under the ice crust. Because of this, Enceladus looks very likely to be a source of life.
I would really, REALLY like to get a sample from those plumes under my microscope.
Hubble Gotchu | Bad Astronomy
I have to say, this made me smile. And even laugh.
True enough, Hubble got me. I can’t even complain that it’s the Bubble Nebula, not galaxy. Even I’m not that picky.
NCBI ROFL: I’d like a number 2 value meal, a frosty, and a peer-reviewed publication, please. | Discoblog
An observational study of consumer use of fast-food restaurant drive-through lanes: implications for menu labelling policy. "OBJECTIVE: ... The present study was designed to quantify the number of customers who purchase fast food through drive-in windows as a means of informing legislative labelling efforts. DESIGN: This was an observational study. SETTING: The study took place at two McDonald's and Burger King restaurants, and single Dairy Queen, Kentucky Fried Chicken, Taco Bell and Wendy's restaurants. SUBJECTS: The number of customers entering the chain restaurants and purchasing food via the drive-through lane were recorded. A total of 3549 patrons were observed. RESULTS: The percentage of customers who made their purchases at drive-throughs was fifty-seven. The overall average (57 %) is likely a conservative estimate because some fast-food restaurants have late-night hours when only the drive-throughs are open. CONCLUSIONS: Since nearly six in ten customers purchase food via the drive-through lanes, menu labelling legislation should mandate the inclusion of menu labels on drive-through menu boards to maximise the impact of this public health intervention." Photo: flickr/s2art Related content:
Discoblog: NCBI ROFL: Alice Waters would not approve.
Discoblog: NCBI ROFL: Fresh squeezed orange juice odor: a review.
Discoblog: NCBI ROFL: eat me.
More vaccination news, some good, some not so good | Bad Astronomy
Some vaccine news I missed in the past few days…
1) A pertussis outbreak in California has already killed two infants. This event resonates with what happened in Australia a year ago; vaccination rates are low, and the victims are too young to be vaccinated themselves. With herd immunities compromised, the littlest and most defenseless reap the effects. This is not necessarily caused by the antivaxxers, but it’s worth noting.
2) There is apparently a small outbreak of polio in Tajikistan. Vaccinations are critical, but so is sanitation.
3) PBS airs a documentary called "The Vaccine Wars" tonight. It’s about what you think it’s about. Check your local listings.
4) H1N1 is still out there, and still hurting and killing kids.
5) A bunch of kids got pretty sick after vaccinations in Australia. It’s unclear what happened, and officials are investigating it.
6) The good news? At least for Finland, it’s good: 97% of kids there are vaccinated. For everything. Amazing.
Tip o’ the needle to Antti Säämänen, Doug Troy, William Mount, and Greg Stitz.
Blogginess | Cosmic Variance
A handful of fun things that shouldn’t pass unremarked:
- Natalie Wolchover, an aspiring science writer, has started a fun blog called Facto Diem. For those of you who didn’t attend Catholic school, that’s Latin for “Fact of the Day.” (Or a close enough facsimile.) I didn’t even know there were that many facts in the world!
- In the more venerable sections of the blogosphere, Chad Orzel is running a poll concerning the most amazing application of lasers. Considering that “death ray” is not among the options, it’s a pretty good list.
- We should also link to Scientia Pro Publica #27, over at Melliferax. (Clearly Latin is the lingua franca of the science blogosphere.) Most of the posts involve living things in some way or another, but they should nevertheless be of interest to those of us with more inorganic inclinations.
Elephants Emit Special “Bee Rumble” to Warn Others About Marauding Bugs | 80beats
When it comes to the relationship between bees and African elephants, size does not matter. The massive pachyderms are terrified of bees, which can painfully sting elephants around their eyes and inside their trunks. Baby elephants are the most vulnerable to bee stings, as their skin isn’t thick enough to ward off the insects. And researchers have now found that the elephants have developed a special strategy to help them avoid these bees that scare the bejesus out of them.
When an elephant takes note of a swarm of bees, it emits a distinct rumbling call. This bee alarm, which the scientists termed a “bee rumble,” helps draw the herd’s attention to the bees and allows them to run off unharmed, the researchers write in the journal PloS ONE. What’s more, they respond to an audio recording of the bee rumble as if it were the real thing, giving farmers a tool they could potentially use to fend off unwanted elephants.
This is the first time that an alarm call for a specific threat has been identified in elephants. Lead researcher Lucy King of the University of Oxford believes that such calls may be an “emotional response” to a threat and a way to co-ordinate group movements. Ms King explained: “We discovered elephants not only flee from the buzzing sound, but make a unique rumbling call, as well as shaking their heads” [BBC]. The head-shaking looked like an attempt to fend off or dislodge the bees that the elephants assumed were buzzing around, King says.
For the study, King and her team played the recordings of the bee rumble vocalization to 10 elephant families. Six of the families immediately got up and fled, despite the fact that they had neither seen nor heard any bees. When the scientists tweaked the vocalization a bit to remove a key acoustical feature found in bee rumbles, the elephants stayed put. The researchers suggest that elephants may also have warning calls to alert their fellows to humans and lions—much like Diana monkeys in West Africa can call out a leopard alarm or eagle alarm, depending on which predator they spot [ScienceNOW].
King hopes that recordings of the bee rumble can be used by farmers to chase away elephants and keep them from trampling fields. As agriculture expands in Africa, elephants have been squeezed into tighter habitats–causing them to stray across fields and damage crops. “Farmers will do anything to keep their crops and families safe from damage, and unfortunately records of shootings, spearings, and poisonings of elephants are on the increase,” Ms King wrote on the University of Oxford’s website [BBC]. King hopes that playing back the bee rumble around fields could serve as a low-tech, humane deterrent to elephants, who will then be sent packing back into the woods.
Related Content:
80beats: Elephants’ Tail Hairs Tell a Story of Competition on the Savanna
80beats: Zoo Elephants’ Lives Cut Short by Obesity, Loneliness
80beats: Elephant-Lovers Worry About Controversial Ivory Auctions in Africa
80beats: Memories of Hard Times Might Help Elephants Survive Global Warming
Image: Lucy King/Oxford University
DARPA Loses Contact with Mach 20 “Hypersonic Glider” During Test Flight | 80beats
It was a big week for experimental military aircraft, with the Air Force’s secretive X-37B space plane and the Navy’s biofuel-powered “Green Hornet” both achieving successful test flights. But the most ambitious—the HTV-2 hypersonic glider under development by the Defense Advanced Research Projects Agency (DARPA)—lost contact with its operators during its run.
Launched from Vandenberg AFB, Calif. on April 22, the unmanned HTV-2 was planned to cross the Pacific and impact the ocean north of Kwajalein Atoll in the first of two flights to demonstrate technology for a prompt global strike weapon [Aviation Week]. It successfully achieved separation from its booster rocket high in the atmosphere; however, nine minutes into the test the glider lost communication. Now the military is studying the test flight telemetry to figure out where the HTV-2 would have crashed down.
Thursday’s mission was the first of two planned in the HTV-2 program, which uses Minotaur 4 boosters developed by Orbital Sciences Corp. from decommissioned Peacekeeper intercontinental ballistic missiles. The U.S. military is trying to develop technology to respond to threats around the globe at speeds of Mach 20 or greater, according to DARPA [AP]. DARPA is being fairly tight-lipped about possible uses for the HTV-2, but it’s not hard to see why the military would be excited about an aircraft that travels about 13,000 miles per hour and can strike on the other side of the world with “little or no advanced warning,” as the agency says.
Program manager Paul Erbland says the key to HTV-2 flying at such speed and height is its carbon shell, which is capable of withstanding extreme heat and pressure. It doesn’t burn off material to get rid of heat. The vehicle is designed to fly at a low angle of attack relative to other hypersonic vehicles. “Shuttle and similar vehicles fly at roughly 40°; HTV-2 is substantially below that,” he said [Aviation Week]. As for the communications failure, DARPA has some time to address the problem before the craft’s second planned test flight next March.
Related Content:
80beats: Will the Pentagon Build the Jetsons’ Flying Car?
80beats: Highway to the Green Zone? Navy To Test a Supersonic Biofuel Jet
80beats: DARPA Wants a Biofuel Jet, While Germany Works on a Hydrogen Plane
80beats: DARPA’s Kooky $40,000 Scavenger Hunt
Image: DARPA