To See the Brain Better, Cut Away Some of That Pesky Skull | Discoblog

brain-chunkWhat do your cell-phone and a brain scan have in common? Both need clear signals for optimal efficacy.

Doctors often have to work with sketchy data when it comes to brain scans–but the solution to that problem isn’t one that many patients will clamor to try. A new study to be published in a forthcoming issue of the Journal of Cognitive Neuroscience says the best way to get clearer EEG brain scans is to remove a part of the skull.

For years, doctors have been treating patients who have suffered severe head trauma like a gunshot or knife wound by cutting out a chunk of the skull–a procedure called a hemicraniectomy. This gives the brain room to swell, and when the wound heals they re-attach the chunk of skull.

Neuroscientist Bradley Voytek of the University of California at Berkeley, the lead author of this study, worked with hemicraniectomy patients and utilized this window to see how the skull acts as a barrier to EEG’s–a brain scan that is done to assess the brain’s electrical activity.

Wired reports that the patients were instructed to peform simple tasks:

During these tasks the team measured a patient’s brain waves on both sides of his head. On one side, just a thin flap of skin separated the brain from the EEG electrode, while on the other side the skull was intact. Signals from the skull-free side were, unsurprisingly, much stronger, less noisy and easier to pinpoint to a specific task and region of the brain.

The study not only offers a creepy way to get clearer brain scans, it also suggests another way to situate neural implants, like the kind that may one day be used by paralyzed people to relay their brain signals to prosthetic limbs. Researchers note that it’s difficult to maintain a long-term electrode in the brain, but some delicate brain signals aren’t strong enough to be read from outside the skull. By drilling a small hole into the skull and placing the electrode on the outermost surface of the brain, the researchers think they might obtain better brain signals.

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Image: Bradley Voytek


From Eternity to Book Club: Chapter Two | Cosmic Variance

Welcome to this week’s installment of the From Eternity to Here book club. Today we look at Chapter Two, “The Heavy Hand of Entropy.”

[By the way: are we going too slowly? If there is overwhelming sentiment to move to two chapters per week, that would be no problem. But if sentiment is non-overwhelming, we'll stick to the original plan.]

Excerpt:

While it’s true that the presence of the Earth beneath our feet picks out an “arrow of space” by distinguishing up from down, it’s pretty clear that this is a local, parochial phenomenon, rather than a reflection of the underlying laws of nature. We can easily imagine ourselves out in space where there is no preferred direction. But the underlying laws of nature do not pick out a preferred direction of time, any more than they pick out a preferred direction in space. If we confine our attention to very simple systems with just a few moving parts, whose motion reflects the basic laws of physics rather than our messy local conditions, there is no arrow of time—we can’t tell when a movie is being run backward…

The arrow of time, therefore, is not a feature of the underlying laws of physics, at least as far as we know. Rather, like the up/down orientation space picked out by the Earth, the preferred direction of time is also a consequence of features of our environment. In the case of time, it’s not that we live in the spatial vicinity of an influential object, it’s that we live in the temporal vicinity of an influential event: the birth of the universe. The beginning of our observable universe, the hot dense state known as the Big Bang, had a very low entropy. The influence of that event orients us in time, just as the presence of the Earth orients us in space.

This chapter serves an obvious purpose — it explains in basic terms the ideas of irreversibility, entropy, and the arrow of time. It’s a whirlwind overview of concepts that will be developed in greater detail in the rest of the book, especially in Part Three. As a consequence, there are a few statements that may seem like bald assertions that really deserve more careful justification — hopefully that justification will come later.

Here’s where I got to use those “incompatible arrows” stories I blogged about some time back (I, II, III, IV). The fact that the arrow of time is so strongly ingrained in the way we think about the world makes it an interesting target for fiction — what would happen if the arrow of time ran backwards? The straightforward answer, of course, is “absolutely nothing” — there is no prior notion of “backwards” or “forwards.” As long as there is an arrow of time that is consistent for everyone, things would appear normal to us; there is one direction of time we all remember, which we call “the past,” when the entropy was lower. It’s when different interacting subsystems of the universe have different arrows of time that things get interesting. So we look briefly at stories by Lewis Carroll, F. Scott Fitzgerald, and Martin Amis, all of which use that trick. (Does anyone know of a reversed-arrow story that predates Through the Looking Glass?) Of course these are all fantasies, because it can’t happen in the real world, but that’s part of the speculative fun.

Then we go into entropy and the Second Law, from Sadi Carnot and Rudolf Clausius to Ludwig Boltzmann, followed by some discussion of different manifestations of time’s arrow. All at lightning speed, I’m afraid — there’s a tremendous amount of fascinating history here that I don’t cover in anywhere near the detail it deserves. But the real point of the chapter isn’t to tell the historical stories, it’s to emphasize the ubiquity of the arrow of time. It’s not just about stirring eggs to make omelets — it has to do with metabolism and the structure of life, why we remember the past and not the future, and why we think we have free will. Man, someone should write a book about this stuff!


On LOST, Time Travel, and the Final Season | The Intersection

With one week until the premiere of the final season of LOST, let’s consider the possibilities for what might happen next…

At this point in the story, the island has stopped jumping through time, but some survivors stuck in the past have just detonated–or attempted to detonate–a conveniently placed nuclear bomb. If successful, they could change everything.

Their plan was first concocted by the island’s resident physicist, Daniel Faraday, who figured out that variables (i.e., time travelers) may be able to alter the future, but unfortunately, he was shot by his own mother–who was pregnant with him at the time. So the other survivors took up Faraday’s mission to change what’s to come, reasoning that if the island and its mysterious energy no longer existed, their plane would not have crashed, they would not meet each other, and the entire first five seasons would never take place!

Where are we now? It also seems that master manipulator Benjamin Linus was just a pawn for the even greater master manipulating smoke monster (a.k.a., the Egyptian god Set?) who found his loophole to kill Jacob in John Locke. However, we suspect Jacob anticipated what would take place and set a series of events in motion by visiting each of the main characters before they reached the island, possibly derailing the smoke monster’s plan so his own murder would never happen. Further, it appears that this is a sort of game the two play: Endlessly calling travelers to their island to move them about like chess pieces. And Jacob always triumphs… so far.

Still with me? So this thread’s just for fun for all of the LOST fans out there. Let’s speculate on what’s to come in the final season and whether Jughead can actually change the future–or if it’s all been done before. What do readers think? I’ll get us started with a similar question to one I posed last year:

If you theoretically travel back in time to change the future–only to realize you’ve already been there and failed–might free will result in different choices leading to new and alternative realities?


There Goes Another Biofuel Ide

Every time there is a great idea concerning biofuels it eventually turns out to be less than advertised.  I thought algae would be something that could pan out as a brilliant form of fuel for the future.  It would be easy to grow and would not compete with food for land.  At present, though, it creates more net CO2 than expected.  The CO2 production would not be a one-off, it would be something that would be repeated as more fuel is made, over and over again.   Last week, the government doled out more than $80 million in stimulus money for biofuels research, much of which will be focused on algae research.  From GreenInc. and e360:

Chris Richards for The New York Times: The need to feed nutrients directly to the water could be a limiting factor in the utility of algae as a biofuel, a new study suggests.

Growing algae for biofuels is an energy-intensive process that can generate more greenhouse gases than the process sequesters, according to a new study. Examining the life cycle of algal biofuels, researchers from the University of Virginia found that the process emits high levels of greenhouse gases because algal production requires using large amounts of fertilizer. Those fertilizers often come from petroleum-based sources, and fertilizers also emit nitrous oxide, a greenhouse gas, according to the study.

The study, published in the journal Environmental Science and Technology, said that while biofuel production from crops such as corn, canola, and switchgrass can result in a net carbon dioxide uptake, that is not yet the case with algal biofuels.  The paper said that one promising way to overcome the environmental impact of using fertilizers to grow algal biofuels is to produce them with effluent from sewage treatment plants. Proponents of algal biofuels also said it is too early to make firm conclusions about the environmental impact of the technology because it is still in its infancy.

This is disappointing!  The paper suggests that one way to reduce the environmental impact of algae is to draw city wastewater into algae plantations, as a source of nitrogen and phosphorus.

This could reduce the amount of fertilizer required, said Dr. Jardine.

Numerous companies, large and small, are investing resources in algae biofuel research, including Exxon Mobil, which last summer devoted $600 million to the endeavor.

EXXON is also surprising us in other ways . . . . or not.  Turns out Exxon backs a carbon tax.  No kidding!   They want themselves taxed for carbon!

Oil giant comes in from the cold

Exxon funded global warming denial for years. Yesterday, in an astonishing U-turn, it called for the imposition of green taxes.

By Stephen Foley in New York

The boss of ExxonMobil, the world’s largest oil company, has called for a carbon tax to tackle global warming, marking a volte-face by the firm once described by Greenpeace as Climate Criminal No 1. Assailed from all sides by scientists and a new cadre [...]

The Disastrous Setback for Climate Advocacy of Late 2009 | The Intersection

Eric Berger of the Houston Chronicle has a really important article out about how, basically, the good guys lost a major battle in the climate war over the past few months. Some combination of the weather, ClimateGate, the relative failure of Copenhagen, and now, the decreasing likelihood of the U.S. Senate passing cap and trade have shifted a mood of climate optimism–which I certainly felt about a year ago–to one of deep despair. “The climate surrounding climate change has changed, and not for the better for those seeking to reduce carbon dioxide emissions,” writes Berger. Sadly, I have to agree.

What went wrong? That’s a very long story, and Berger relates much of it. For my part, I am convinced the fundamental factor is that our camp egregiously misunderestimated the skeptic/denial camp and what it was capable of. Our thinking went something like this: “the science keeps getting stronger, and now we have Obama…the tide has turned.” And so we were lulled into a false sense of security. Now, there is a hell of a lot of regrouping to do, and I am not even sure where to begin. But one thing is certain: We should never again assume that science alone is going to make the political difference on this issue, no matter how strong it gets.


Lung cancer symptoms


The symptoms of lung cancer can be many and various. Around one-fourth of those actually diagnosed with lung cancer present no symptoms at the time of diagnosis. Diagnosis and identification of the cancer normally occurs incidentally when the patient has a chest x-ray for an unrelated reason. The remaining three-fourths do develop certain commonly-known symptoms, and these are a direct result of the effects of the primary tumor as well as the effects of metastatic tumors elsewhere in the body.

Perhaps the most common – and most important – identifying symptom of lung cancer is the cough. It is, however, hard to tell such a cough related to lung cancer apart from a cough related to smoking or with chronic respiratory problems such as COPD, which also is a result of smoking. In the case of a patient with a chronic cough it is important to identify any changes in the pattern of the cough, as this could indicate the potential for lung cancer. Also, a new cough in either a smoker or an ex-smoker should also raise concerns and should be check out by a health care professional as soon as possible. This of also true of any persistent cough that does not get better over the course of time.

Another associated symptom is shortness of breath, and this also can be hard to tell apart from that related to the condition COPD as mentioned above. Again, just as in the case of coughing, any changes in the patient’s patterns of breathing difficulties should raise concerns sufficiently to ensure that a health care professional is consulted.

People should also pay attention to a symptom called hemoptysis, which involves the spitting or coughing up of blood. In the case that this symptom presents itself in someone with a history of smoking the possibility of lung cancer should be highly suspected and work and tests should be undertaken to rule the condition out.

Also, repeated respiratory infections such as bronchitis or pneumonia should be a cause for concern. In fact, in many cases pneumonia is a common way in which lung cancer makes itself known initially as the growing cancerous tumor can cause the airways to become obstructed, resulting in something known as post-operative pneumonia. In such cases it is advisable for patients to obtain repeat chest x-rays in order to ensure that the pneumonia is totally cleared.

Lung cancer may also cause fluid in the lungs if it spreads to either the inner or outer lung coverings, which causes fluid accumulation between the lung and the chest wall. In the event that this occurs the patient may well experience shortness of breath and, in the event that the cancer has entered the chest wall, patients may experience chest pain too. This should cause special red flags to physicians examining patients at high-risk of lung cancer. Patients may also experience bone and joint pain, as a result of tumors in the apex of the lung infiltrating the nearby nervous structures resulting in shoulder or arm pain.

Patients can also see changes in their voice patterns, with constant hoarseness also being a possible symptom as well as having difficulty swallowing. Patients may also experience weight loss, anemia and fatigue.

A Question of Ethics

This isn’t really about astronomy, but in a way, it is.  I was cruising around the web the other day, and I went to a site I usually visit because of amusing content and comments.  The site had used 15 images produced by NASA et al, ESA et al, and various astrophysicists to illustrate that day’s post, but none of the images were credited.  Not a single one.  I commented on it, and wrote the site owner twice, but nothing was done to credit the owners of these images.  I never got a response, either – not from my comment or my two emails.

What’s that called in the digital era?  We used to call it “rude”, “copyright infringement”, and “theft”.

Organizations like NASA and ESA don’t care if you use their images; they want people to see them and enjoy them.  That’s why they put them out there.  But you have to credit the image, guys.  These agencies and the people working for them depend on public recognition of their work for funding.  If you didn’t know it was Hubble that put all those amazing images out all those years, do you think we’d still have the program?  No way.  The Hubble would have been shut down within two years, and look at all we would have lost.

I think it’s wrong.  There’s no excuse for it, especially when it’s so easy to credit the image.  I mean, it’s written right THERE to whom it belongs, you can’t miss it when you go to NASA or HubbleSite or wherever to get the image… it just takes 30 sec worth of typing to attribute the image.  Forgetting is one thing; blowing it off is another.

I’m still kicking around whether or not I should link the site to NASA and ESA and let them contact the site owner… because they will if they know about it.  They’re very careful about attribution, because it matters to them.

And it should matter to us.

January 25 2010 Escuela

Tengo mi primera dia en la escuela hoy. You estoy en el groupo intermediado. Cuando llegar en la escuela tomamos en groupos de cuartro o cinco personas por la manana para gramatica. Despues del almuerzo muovamos a una groupa mas largo con siete personas para conversation de la diabetes.La escuela es muy bonita con muchas salas y una piscina.Despues de las clases muchas personas caminan al cen

Brisbane area

Just as Borneo marked an end to 6 months of backpacking SouthEast Asia so Brisbane marks the begining of a new trip...A change of pace and a change of means of locomotion...The idea is to cycle my way down the Eastern Australian coast taking it as slow as necessary and stopping frequently for long periods of time in order to do some farm work WWOOFing.If all goes well I'll eventually end u

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Busy in Coban

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Down South with the family in Dunsborough

The funny thing is that while I lived in Perth from the ages of 12 to 22 I never managed to make it ldquodown southrdquo which is the term generally used to encompass the areas immediately surrounding Busselton Dunsborough and Margaret River. This came about partially because I didn't have a car partially because the roads down there were not great and partially due to lack of interest. I ha

Camper Litchfield

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Michel in Honduras

I have lived and worked in many area of Honduras for 15 years and am fluent in Spanish. I have worked in health care and tourism for small NGO's and also for organizations like the WHOPAHO and the Secretaria de Salud. In the years that I have been here I have made many contacts and have always been able to find answers for the tourists that I in contact with on a daily basis.As a volunteer at var

Bangkok Fashion House Don’t go there

I had some shirts and pants made at Bangkok Fashion House tailors next to Four Sons Place. They stuffed me around arrived late knowing I was leaving so I wouldn't have a chance to make changes if necessary which it was because the tailoring was average at best eg buttons not aligned threads everywhere. They also had a shocking attitude once the deposit was paid. With so many tailors around g

Borneo

17 to 23rd of January.Sabah North Eastern Borneo and Sarawak North Western Borneo are the two largest states in the Malaysian Federation. They also represent approx 13 of the area of the island of Borneo. Borneo is the 3rd largest island in the World. The locals call it ldquothe land below the windrdquo. It is a region that has not been hit by earthquakes typhoons hurricanes or volcan

"im a bilingual"

Ok so I was going to update this yesterday but I was having kind of an off day so I put it off. I didn't want to take out my frustration with the Spanish language in my blog so I just whined to my family . My frustration came as a result of being in my room all day struggling through my homework. Homework that would've taken me at most half of the time that this took had it been in English. 4