In Lung Cancer, Not All HER2 Alterations Are Created Equal Jan. 28, 2016 Study shows two distinct causes of HER2 activation in lung cancer: mutation of the gene and amplification of the gene. In patient samples of lung adenocarcinoma, 3 percent were found to have HER2 ... read more Dec. 12, 2015 Results from a long-term clinical trial conducted by cancer researchers show that combining radiation treatment with 'suicide gene therapy' provides a safe and effective one-two punch ... read more Gene Therapy Used to Extend Estrogen's Protective Effects on Memory Dec. 8, 2015 The hormone estrogen helps protect memory and promote a healthy brain, but this effect wanes as women age, and even estrogen replacement therapy stops working in humans after age 65. Now researchers ... read more Shrinking Tumors With an RNA Triple-Helix Hydrogel Glue Dec. 7, 2015 An efficient and effective delivery vehicle for gene therapy has been developed by researchers who have used it to shrink tumors by nearly 90 percent in a pre-clinical model of triple-negative breast ... read more Characteristics That May Increase a Breast Cancer Survivor's Risk of Developing Leukemia Following Treatment Identified Dec. 7, 2015 A new analysis indicates that certain characteristics may increase a breast cancer survivor's risk of developing leukemia after undergoing chemotherapy and/or radiation. The findings are a first ... read more Early Gene Therapy Results in Wiskott-Aldrich Syndrome Promising Dec. 6, 2015 Researchers reported promising preliminary outcomes for the first four children enrolled in a US gene therapy trial for Wiskott-Aldrich syndrome (WAS), a life-threatening genetic blood and immune ... read more Gene Therapy Restores Immunity in Children and Young Adults With Rare Immunodeficiency Dec. 6, 2015 Gene therapy can safely rebuild the immune systems of older children and young adults with X-linked severe combined immunodeficiency (SCID-X1), a rare inherited disorder that primarily affects males, ... read more MECP2 Duplication Syndrome Is Reversible, Study Suggests Nov. 25, 2015 The MECP2 Duplication Syndrome is reversible, say researchers. Importantly their study paves the way for treating duplication patients with an antisense oligonucleotide ... read more Gene Therapy: Promising Candidate for Cystic Fibrosis Treatment Nov. 16, 2015 An improved gene therapy treatment can cure mice with cystic fibrosis (CF). Cell cultures from CF patients, too, respond well to the treatment, suggest new encouraging ... read more Link Found Between Genetic Mutations, Proliferation, Immune Surveillance in Lung Cancer Nov. 11, 2015 There are four gene mutations (KRAS, TP53, STK11, and EGFR) that most commonly occur in lung cancer; however, there are limited effective therapies to target these mutations. With this in mind, ... read more Nov. 9, 2015 Genome editing techniques for blood stem cells just got better, thanks to a team of researchers. In a new article, they describe a new, more efficient way to edit genes in blood-forming or ... read more Nov. 2, 2015 Eye drops have been used to deliver the gene for a growth factor called granulocyte colony stimulating factor (G-CSF) in a mouse model of brain ischemia. The treatment led to a significant reduction ... read more Oct. 21, 2015 Delivering the hormone leptin directly to the brain through gene therapy aids weight loss without the significant side effect of bone loss, according to new ... read more New Study Explains Why You Bulk Up With Resistance Training, Not Endurance Training Oct. 20, 2015 Resistance and endurance exercises activate the same gene, PGC-1?, but the processes stimulated for the muscles to adapt depend on the exercise type. A new study offers insight into why the physical ... read more Researchers Identify Gene That Increases Risk of Sudden Death in Patients With Mild Epilepsy Oct. 15, 2015 A gene mutation that increases the risk of sudden unexpected death in epilepsy (SUDEP) in patients with mild forms of the disease has been discovered by a group of ... read more Oct. 8, 2015 Compared with direct gene injection, cell-mediated GDNF gene delivery led to considerably more pronounced preservation of myelinated fibers in the remote segments of the spinal cord (5 vs 3 mm from ... read more 'Alarm Clock' of a Leukemia-Causing Oncogene Identified Oct. 8, 2015 Mutations in DNMT3A gene cause MEIS1 activacion, triggering leukemia, a research team ... read more Oct. 5, 2015 A novel mouse model for the vision disorder Leber hereditary optic neuropathy (LHON) has been developed by researchers who have found that they can use gene therapy to improve visual function in the ... read more Genetic Polymorphism Associated With Lung Cancer Progression Oct. 5, 2015 Genetic polymorphisms associated with cancer progression lead to variations in gene expression and may serve as prognostic markers for lung cancer, researchers show. They found that in patients with ... read more New Hope for Lou: Unexplored Therapeutic Targets for ALS Sep. 3, 2015 No cures exist for amyotrophic lateral sclerosis (ALS), and the only approved therapy slows the progression by only a few months. A new study identifies a promising unexplored avenue of treatment for ... read more

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Gene Therapy News -- ScienceDaily