Mining Genome Information for New Starting Points in Personalized Cancer Nanomedicine
Speaker: Prof. Dr. Jan Mollenhauer, NanoCAN, University of Southern Denmark (DK) "Clinical Nanomedicine Targeted Medicine", The European CLINAM ETPN Summ...
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Mining Genome Information for New Starting Points in Personalized Cancer Nanomedicine - Video
Global Nanomedicine Market has been brewing up and impacting the international economy in terms of growth rate, revenue, sale, market share, and size. The Global Nanomedicine Market research report renders lucid explanation to the reader to study fundamental attributes of Nanomedicine industry which includes lucrative business strategies, market demands, leading player of the market, and futuristic perspective through various angles.
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As the Nanomedicine industry has been exhibiting substantial growth rate over the previous decade and expected to perform vigorously in forthcoming decades, it is being necessary to identify all investment opportunities, upcoming market threats, challenges, restraining factors, market dynamics, and technological advancements to strengthen footholds in Nanomedicine industry. The proposed research has studied all the above elements to render a thorough analysis to the reader that drives to achieve expected growth in their businesses.
Why B2B Companies Worldwide Rely on us to Grow and Sustain Revenues: Get a clear understanding of the Nanomedicine market, how it operates and the various stages of the value chain. Understand the current market situation and future growth potential of the Nanomedicine market till 2019 and plan strategies to gain from it. Strategize marketing, market-entry, market expansion, and other business plans by understanding factors influencing growth in the market and purchase decisions of buyers. Understand your competitors business structures, strategies and prospects, and respond accordingly. Make more informed business decisions with the help of insightful recommendations provided to succeed in the Nanomedicine market.
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Nanomedicine Market Major Players in Nanomedicine Market are: GE Healthcare, Johnson & Johnson, Mallinckrodt plc, Merck & Co. Inc., Nanosphere Inc., Pfizer Inc., Sigma-Tau Pharmaceuticals Inc., Smith & Nephew PLC, Stryker Corp, Teva Pharmaceutical Industries Ltd., UCB (Union chimique belge) S.A
Most widely used downstream fields of Nanomedicine Market: Clinical Cardiology, Urology, Genetics, Orthopedics, Ophthalmology
Market Analysis by Types: Regenerative Medicine, In-vitro & In-vivo Diagnostics, Vaccines, Drug Delivery
Market Analysis by Geographies: This report is segmented into key Regions North America, Europe, China, Japan, Southeast Asia & India with Production Development, Sales, and Regional Trade & Forecast.
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The report elaborates competitive landscape considering mergers and acquisitions, joint ventures, partnerships, wind ups, strategic alliances, product developments, latest technological advancement, and research and developments in global Nanomedicine industry along with a forecast of emerging industry trends up to 2025.
Additionally, the report discusses lucrative business strategies of market competitors by lightning specific moves of competitors including business expansion, amalgamations, partnership deals, new product/service launches, and recently adopted technologies.
If you have any customized requirement need to be added, we will be happy to include this free of cost to enrich the final study.
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Global Healthcare Nanotechnology (Nanomedicine) Market comprehensive analysis of the business models, key ways, and individual market shares of some of the most outstanding players during this landscape. AN in-depth statement on the key influencing factors, market statistics in terms of revenues, segment-wise knowledge, region-wise knowledge, and country-wise knowledge are offered within the full study. with growth trends, numerous stakeholders like investors, CEOs, traders, suppliers, analysis & media, international Manager, Director, President, SWOT analysis i.e. Strength, Weakness, Opportunities and Threat to the organization and others. This report focuses on Professional Global Healthcare Nanotechnology (Nanomedicine) Market 2020-2024 volume and value at Global level, regional level and company level.
Global Healthcare Nanotechnology (Nanomedicine) Market 2020report provides key statistics on the market status of the Healthcare Nanotechnology (Nanomedicine) Manufacturers and is a valuable source of guidance and direction for companies and individuals interested in the Healthcare Nanotechnology (Nanomedicine) Industry. The Healthcare Nanotechnology (Nanomedicine) industry report firstly announced the Healthcare Nanotechnology (Nanomedicine) Market fundamentals: type applications and market overview; product specifications; manufacturing processes; cost structures, raw materials and so on.
Nanomedicine is a promising mode of cancer treatment. With the advantage of the properties of matter at nanoscale, nanomedicine promises to develop innovative drugs with greater efficacy and lesser side effects than standard therapies.
Healthcare Nanotechnology (Nanomedicine)market competition by top manufacturers/ Key player Profiled:
Abbott Laboratories,Combimatrix Corporation,GE Healthcare,Sigma-Tau Pharmaceuticals Inc.,Johnson and Johnson,Mallinckrodt Plc,Merck and Company Inc.,Nanosphere Inc.,Pfizer, Inc.,Celgene Corporation,.
And More
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Healthcare Nanotechnology (Nanomedicine) Market Segment by Type covers:
Healthcare Nanotechnology (Nanomedicine) Market Segment by Applications can be divided into:
Regional analysis covers:
Scope of theHealthcare Nanotechnology (Nanomedicine) MarketReport:
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Key questions answered in the report:
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The next part also sheds light on the gap between supply and consumption. Apart from the mentioned information,growth rateof Healthcare Nanotechnology (Nanomedicine) market in 2025is also explained.Additionally, type wise and application wise consumptiontables andfiguresof Healthcare Nanotechnology (Nanomedicine) marketare also given.
Objective of Studies:
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Insect Repellent Market 2020: Global Industry Size, Share, Future Challenges, Revenue, Demand, Industry Growth and Top Players Analysis to 2024
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To view the original version on The Express Wire visit Healthcare Nanotechnology (Nanomedicine) Market 2024 Trends Forecast Analysis by Manufacturers, Regions, Type and Application Revenue, Gross Margin Forecast Analysis| 360 Market updates
From diagnosis supported by artificial intelligence (AI), to 3D printing, virtual reality pain management, nanomedicine, and telemedicine technology is transforming the healthcare sector. In many ways, technology is a boon to the industry. According to the Association of American Medical Colleges, the US faces a shortage of between 40,800 and 104,900 physicians by 2030. Emerging technologies can help with this problem by expediting diagnoses and allowing physicians to focus on complex cases.
However, change almost always comes hand in hand with new risks. As healthcare organizations and professionals start to incorporate more technology into their businesses, they face heightened liability risks, malpractice or misdiagnosis claims, data privacy and cyber security concerns, and property exposures.
Greg Wideman (pictured), brokerage manager, professional and executive liability, Burns & Wilcox, commented: The healthcare insurance industry has become increasingly challenging due to emerging technology. Brokers are under pressure to find comprehensive coverage solutions for these new technologies and explain how they work in order to ensure adequate protection.
As healthcare organizations adopt new technologies, the expectation is that diagnoses and services will ultimately improve, in terms of both accuracy and efficiency. This social expectation has impacted the insurance industry by increasing the severity of healthcare claims. Should litigation arise, plaintiffs are being awarded more money than they were in the past because there is the belief that with new technologies in place, physicians should not be making mistakes.
A leading cause of loss in the healthcare insurance industry is misdiagnosis or no diagnosis of an existing condition. According to Wideman, this recurring problem can be largely attributed to physicians compensating for a shortage in their ranks by trying to get patients through the system as quickly as possible. Physicians are spending less time with patients and they are asking fewer questions. As a result, misdiagnosis numbers are on the rise, he added.
Some healthcare organizations are turning to telemedicine to enable virtual visits with doctors, nurses or other healthcare specialists, in order to speed up the consultation process. Offering video conferencing, messaging and mobile app-based communication gives patients the option to get check-ups and status updates from a remote location, but it also impacts physicians liability.
Physicians used to physically examine patients and do in-person diagnostic testing, but now a lot of that is being done over the internet or via an app, Wideman told Insurance Business. I think [telemedicine] opens up new liability for physicians because they are not in front of the patient and they are not necessarily asking the questions they would normally ask during an in-person consultation.
Another risk that is becoming increasingly problematic in the healthcare industry is data privacy and cyber liability.
There is a lot of consolidation going on in the healthcare industry right now, with small physician groups combining with hospitals, telemedicine providers, and pharmacy groups. This consolidation is presenting more cyber liability issues, Wideman added. Smaller physician offices struggle to implement the same cyber security practices and maintain the same IT support staff as the larger hospitals and healthcare systems. When they consolidate, that changes the exposure of the overall group.
In the era of electric medical records, cyber criminals are targeting healthcare organizations in order to extract and exploit the sensitive medical information that they hold. Issues could arise in the future with hackers compromising virtual healthcare tools or even commandeering robot-assisted surgical equipment.
In such a fast-paced and changing environment, healthcare providers should review their insurance coverage limits and deductibles with their insurance brokers to ensure they are properly protected, Wideman noted. As we start to see more complicated risks, it is important for brokers to ask in-depth questions to better understand the exposures they are being asked to place. Brokers can work with a wholesale partner, like Burns & Wilcox, for their expertise and trusted counsel in navigating solutions.
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Technology transforming the healthcare industry - Insurance Business
Nanomedicine is a promising mode of cancer treatment. With the advantage of the properties of matter at nanoscale, nanomedicine promises to develop innovative drugs with greater efficacy and lesser side effects than standard therapies.
In 2018, the global Healthcare Nanotechnology (Nanomedicine) market size was xx million US$ and it is expected to reach xx million US$ by the end of 2025, with a CAGR of xx% during 2019-2025.
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This report focuses on the global Healthcare Nanotechnology (Nanomedicine) status, future forecast, growth opportunity, key market and key players. The study objectives are to present the Healthcare Nanotechnology (Nanomedicine) development in United States, Europe and China.
The key players covered in this studyAbbott LaboratoriesCombimatrix CorporationGE HealthcareSigma-Tau Pharmaceuticals Inc.Johnson & JohnsonMallinckrodt PlcMerck & Company Inc.Nanosphere Inc.Pfizer, Inc.Celgene Corporation
Market segment by Type, the product can be split intoBiochipImplant MaterialsMedical TextilesWound DressingOther
Market segment by Application, split intoTherapeuticDiagnosticResearch
Market segment by Regions/Countries, this report coversUnited StatesEuropeChinaJapanSoutheast AsiaIndiaCentral & South America
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The study objectives of this report are:To analyze global Healthcare Nanotechnology (Nanomedicine) status, future forecast, growth opportunity, key market and key players.To present the Healthcare Nanotechnology (Nanomedicine) development in United States, Europe and China.To strategically profile the key players and comprehensively analyze their development plan and strategies.To define, describe and forecast the market by product type, market and key regions.
In this study, the years considered to estimate the market size of Healthcare Nanotechnology (Nanomedicine) are as follows:History Year: 2014-2018Base Year: 2018Estimated Year: 2019Forecast Year 2019 to 2025For the data information by region, company, type and application, 2018 is considered as the base year. Whenever data information was unavailable for the base year, the prior year has been considered.
Table of Contents:
Chapter One: Report Overview
1.1 Study Scope
1.2 Key Market Segments
1.3 Players Covered
1.4 Market Analysis by Type
1.4.1 Global Healthcare Nanotechnology (Nanomedicine) Market Size Growth Rate by Type (2014-2025)
1.4.2 Biochip
1.4.3 Implant Materials
1.4.4 Medical Textiles
1.4.5 Wound Dressing
1.4.6 Other
1.5 Market by Application
1.5.1 Global Healthcare Nanotechnology (Nanomedicine) Market Share by Application (2014-2025)
1.5.2 Therapeutic
1.5.3 Diagnostic
1.5.4 Research
1.6 Study Objectives
1.7 Years Considered
Chapter Two: Global Growth Trends
2.1 Healthcare Nanotechnology (Nanomedicine) Market Size
2.2 Healthcare Nanotechnology (Nanomedicine) Growth Trends by Regions
2.2.1 Healthcare Nanotechnology (Nanomedicine) Market Size by Regions (2014-2025)
2.2.2 Healthcare Nanotechnology (Nanomedicine) Market Share by Regions (2014-2019)
2.3 Industry Trends
2.3.1 Market Top Trends
2.3.2 Market Drivers
2.3.3 Market Opportunities
Chapter Three: Market Share by Key Players
3.1 Healthcare Nanotechnology (Nanomedicine) Market Size by Manufacturers
3.1.1 Global Healthcare Nanotechnology (Nanomedicine) Revenue by Manufacturers (2014-2018)
3.1.2 Global Healthcare Nanotechnology (Nanomedicine) Revenue Market Share by Manufacturers (2014-2018)
Continued.
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2019-2025 Healthcare Nanotechnology (Nanomedicine) Market Global Demand and Trends by Type, Application and Specification - News Description
COVID-19s outbreak has coincided with investments flooding into nanomedicine healthcare companies, according to the latest data. The investment monitoring platform reported that the sector benefited by 1.7bn in 2020 - 1.1bn more than the year before.
Nano Magazine has highlighted a report by Market DataForecastthat the global nanomedicine market, worth $141.34 billion in 2020, will rise to $258.11bn by 2025. The report also highlights a huge upsurge of investment support from governments and funds to develop nano therapies for vaccines, diagnostic imaging, regenerative medicine, and drug delivery following the impact of COVID-19.
Furthermore, nanomedicine offers huge advantages for wider healthcare, also affected by the pandemic and Long-COVID after-effects upon cardiovascular, respiratory, neurological, immunological-related diseases.
This aligns with investment monitoring platform Pitchbooks forecast that health tech investment overall will top $10 trillion by 2022 and that nanomedicine investment has grown the sector by 250% in the last five years.
Median nanotech healthcare deal sizes have also doubled since 2019, from 1 million to 2m in 2021, while the number of deals in 2020 was greater than ever, overtaking 100 deals in a single year for the first time.
Nanomedicine is transforming healthcare innovation and delivering early intervention and targeted drug delivery and testingNanomedicine is transforming healthcare innovation and delivering early intervention and targeted drug delivery and testing
Investment is already aiding innovation as nanotech researchers and scientists work to improve biomedical devices such as prosthetics, provide new cancer treatments, and develop bone healing therapies, along with more innovations that could transform global healthcare.
Nanotech researchers have found nanobodies that block the COVID-19 and, potentially, other coronaviruses from entering cells and developed mask designs at nanoscale making them both cheaper and more effective.
The fast global response to the pandemic was also enabled by nanotechnology, being pivotal in Pfizer and AstraZeneca vaccine development and Innova Medical Groups 30-minute lateral flow COVID tests.
World Nano Foundation co-founder Paul Stannard said COVID-19 highlighted weaknesses in healthcare systems across the developed world, proving that long-term, innovative solutions are needed to enable change and prevent future pandemics, with nanomedicine playing an ever-greater role in this transformation of global healthcare.
And while impressed by rising investments in and recognition for the nanotech sector, he warned against any let-up in this trend:
Nanotechnology is not only crucial to our current healthcare systems, but researchers and scientists in this field are on the cusp of therapies, devices, and innovation that will revolutionize how we move forward.
To ensure pandemic preparedness, high-quality healthcare, and longevity, we must invest in nano healthtech and care innovations.
His message was echoed by Kojo Annan (son of late and former UN secretary-general Kofi Annan) who is a general partner in the Luxembourg-based Vector Innovation Fund, which recently launched a sub-fund raising an initial $300m for pandemic protection and preparedness.
Annan said: A virtuous circle is developing between investment and healthtech. Lately, we have seen the development of multiple vaccines, acceleration of technologies linked to decoding the genome, the rise of nanomedicine and the use of artificial intelligence to monitor infectious diseases and new pathogens.
More investment in sustainable healthtech funding can only accelerate this trend, bringing the fairer and global distribution of healthcare, greater affordability, and preventive and early intervention healthcare, all ultimately improving the longevity of life.
The pandemic has also transformed telemedicine investment and demonstrated that nanoscience and innovation could deliver more resilient societies and ecosystems for healthcare.
Korea IT Times
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Surging nanomedicine virtuous circle develops between investment and healthtech - Korea IT Times
New York, November 26, 2019: The report scope includes detailed competitive outlook covering market shares and profiles key participants in the global Nanomedical market share. Major industry players with significant revenue share include Johnson & Johnson, Mallinckrodt plc., Merck & Company, Inc., Nanosphere, Inc., Pfizer, Inc., Teva Pharmaceutical Industries Ltd., Abbott Laboratories, CombiMatrix Corporation, General electric Company, Sigma-Tau Pharmaceuticals, Inc., and others.
The Nanomedical Market is expected to exceed more than US$ 306 Billion by 2024 at a CAGR of 10.3% in the given forecast period.
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Nanomedicine market is mainly driven by increase in acceptance of nanomedicine across diverse applications, rise in government funding & support, emerging technologies for drug delivery, rise in need for therapies with less side effects and allergies, and cost-effectiveness of therapies.
Growing healthcare facilities in developing countries are anticipated to bring numerous opportunities for the growth of nanomedicine market.
Nanomedicine is one of the applications of nanotechnology used in treatment, monitoring, diagnosis, and control of biological systems. Nanomedicine utilizes nanoscale control of materials to improve medicine delivery. Subsequently, nanomedicine has encouraged treatment against different diseases.
The global Nanomedical market is segregated on the basis of Indication as Ophthalmological Diseases, Immunological Diseases, Cardiovascular Diseases, Oncological Diseases, Infectious Diseases, Orthopedic Disorders, Neurological Diseases, Urological Diseases, and Others. Based on Application the global Nanomedical market is segmented in Implants, Regenerative Medicine, Diagnostic Imaging, Drug Delivery, Vaccines, and Others. Based on Modality the global Nanomedical market is segmented in Treatments and Diagnostics.
The global Nanomedical market report provides geographic analysis covering regions, such as North America, Europe, Asia-Pacific, and Rest of the World. The Nanomedical market for each region is further segmented for major countries including the U.S., Canada, Germany, the U.K., France, Italy, China, India, Japan, Brazil, South Africa, and others.
Competitive Rivalry
Johnson & Johnson, Mallinckrodt plc., Merck & Company, Inc., Nanosphere, Inc., Pfizer, Inc., Teva Pharmaceutical Industries Ltd., Abbott Laboratories, CombiMatrix Corporation, General electric Company, Sigma-Tau Pharmaceuticals, Inc., and others are among the major players in the global Nanomedical market. The companies are involved in several growth and expansion strategies to gain a competitive advantage. Industry participants also follow value chain integration with business operations in multiple stages of the value chain.
The Nanomedical Market has been segmented as below:
The Nanomedical Market is segmented on the lines of Nanomedical Market, By Indication, Nanomedical Market, By Application, Nanomedical Market, By Modality, Nanomedical Market, By Region and Nanomedical Market, By Company.
Nanomedical Market, By Indication this market is segmented on the basis of Ophthalmological Diseases, Immunological Diseases, Cardiovascular Diseases, Oncological Diseases, Infectious Diseases, Orthopedic Disorders, Neurological Diseases, Urological Diseases and Others. Nanomedical Market, By Application this market is segmented on the basis of Implants, Regenerative Medicine, Diagnostic Imaging, Drug Delivery, Vaccines and Others. Nanomedical Market, By Modality this market is segmented on the basis of Treatments and Diagnostics. Nanomedical Market, By Region this market is segmented on the basis of North America, Europe, Asia-Pacific and Rest of the World. Nanomedical Market, By Company this market is segmented on the basis of Johnson & Johnson, Mallinckrodt plc., Merck & Company, Inc., Nanosphere, Inc., Pfizer, Inc., Teva Pharmaceutical Industries Ltd., Abbott Laboratories, CombiMatrix Corporation, General electric Company and Sigma-Tau Pharmaceuticals, Inc.
The report covers:
Report Scope:
The global Nanomedical market report scope includes detailed study covering underlying factors influencing the industry trends.
The report covers analysis on regional and country level market dynamics. The scope also covers competitive overview providing company market shares along with company profiles for major revenue contributing companies.
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Table of Contents:
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Nanomedical Market Changing Market Trends, New Business Opportunities Analysis and Forecast with Revenue Growth 2019-2025 - Markets Gazette 24
DataIntelo, one of the worlds prominent market research firms has released a new report on Global Nanomedicine Market. The report contains crucial insights on the market which will support the clients to make the right business decisions. This research will help both existing and new aspirants for Nanomedicine market to figure out and study market needs, market size, and competition. The report talks about the supply and demand situation, the competitive scenario, and the challenges for market growth, market opportunities, and the threats faced by key players.
The report also includes the impact of ongoing global crisis i.e. COVID-19 on the Nanomedicine market and what the future holds for it. The published report is designed using a vigorous and thorough research methodology and DataIntelo is also known for its data accuracy and granular market reports.
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A complete analysis of the competitive scenario of the Nanomedicine market is depicted by the report. The report has a vast amount of data about the recent product and technological developments in the markets. It has a wide spectrum of analysis regarding the impact of these advancements on the markets future growth, wide-range of analysis of these extensions on the markets future growth.
Nanomedicine market report tracks the data since 2015 and is one of the most detailed reports. It also contains data varying according to region and country. The insights in the report are easy to understand and include pictorial representations. These insights are also applicable in real-time scenarios.
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Components such as market drivers, restraints, challenges, and opportunities for Nanomedicine are explained in detail. Since the research team is tracking the data for the market from 2015, therefore any additional data requirement can be easily fulfilled.
Some of the prominent companies that are covered in this report:
CombimatrixAblynxAbraxis BioscienceCelgeneMallinckrodtArrowhead ResearchGE HealthcareMerckPfizerNanosphereEpeius BiotechnologiesCytimmune SciencesNanospectra Biosciences
*Note: Additional companies can be included on request
The industry looks to be fairly competitive. To analyze any market with simplicity the market is fragmented into segments, such as its product type, application, technology, end-use industry, etc. Segmenting the market into smaller components helps in understanding the dynamics of the market with more clarity. Data is represented with the help of tables and figures that consist of a graphical representation of the numbers in the form of histograms, bar graphs, pie charts, etc. Another key component that is included in the report is the regional analysis to assess the global presence of the Nanomedicine market.
Following is the gist of segmentation:
By Application:
Segmentation encompasses oncologyInfectious diseasesCardiologyOrthopedicsOthers
By Type:
Quantum dotsNanoparticlesNanoshellsNanotubesNanodevices
By Geographical Regions
Asia Pacific: China, Japan, India, and Rest of Asia PacificEurope: Germany, the UK, France, and Rest of EuropeNorth America: The US, Mexico, and CanadaLatin America: Brazil and Rest of Latin AmericaMiddle East & Africa: GCC Countries and Rest of Middle East & Africa
You can also go for a yearly subscription of all the updates on the Nanomedicine market.
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Below is the TOC of the report:
Executive Summary
Assumptions and Acronyms Used
Research Methodology
Nanomedicine Market Overview
Nanomedicine Supply Chain Analysis
Nanomedicine Pricing Analysis
Global Nanomedicine Market Analysis and Forecast by Type
Global Nanomedicine Market Analysis and Forecast by Application
Global Nanomedicine Market Analysis and Forecast by Sales Channel
Global Nanomedicine Market Analysis and Forecast by Region
North America Nanomedicine Market Analysis and Forecast
Latin America Nanomedicine Market Analysis and Forecast
Europe Nanomedicine Market Analysis and Forecast
Asia Pacific Nanomedicine Market Analysis and Forecast
Middle East & Africa Nanomedicine Market Analysis and Forecast
Competition Landscape
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DataIntelo has a vast experience in designing tailored market research reports in various industry verticals. We also have an urge to provide complete client satisfaction. We cover in-depth market analysis, which consists of producing lucrative business strategies for the new entrants and the emerging players of the market. We make sure that each report goes through intensive primary, secondary research, interviews, and consumer surveys before final dispatch. Our company provides market threat analysis, market opportunity analysis, and deep insights into the current market scenario.
We invest in our analysts to ensure that we have a full roster of experience and expertise in any field we cover. Our team members are selected for stellar academic records, specializations in technical fields, and exceptional analytical and communication skills. We also offer ongoing training and knowledge sharing to keep our analysts tapped into industry best practices and loaded with information.
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Nanomedicine Market (2020-2026) | Where Should Participant Focus To Gain Maximum ROI | Exclusive Report By DataIntelo - Aerospace Journal
A Basic Introduction to Nanomedicine Market.
The Nanomedicine market report emphasizes on latest data such as driver, emerging trends, and opportunities. This document also covers other important information such as size, restraints, share, challenges, and major players for the forecast period of 2021-2028. The report includes the SWOT analysis of leader companies from the global Nanomedicine market. It also enlists and analyzes the most recent market developments shaping the future of the foremost players and industry.
The report puts a special emphasis on key driving and restraining factors for the market, along with a comprehensive study of the emerging trends and future developments of the market. The report further provides an elaborate study of micro-and macro-economic aspects that are anticipated to influence the demand for the market.
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Major players covered in this report: GE Healthcare, Johnson & Johnson, Mallinckrodt plc, Merck & Co. Inc., Nanosphere Inc., Pfizer Inc., Sigma-Tau Pharmaceuticals Inc., Smith & Nephew PLC, Stryker Corp, Teva Pharmaceutical Industries Ltd., UCB (Union chimique belge) S.A
Following the fundaments, the market is segmented on the basis of geography:
This report studies the top players, focuses on product capacity, production, value, consumption, market share and growth opportunity from this geographies, covering basis of geography: North America (U.S., Canada, Mexico), Europe (U.K., France, Germany, Spain, Italy and Rest of Europe), Asia Pacific (China, Japan, South Korea, ASEAN, India, Rest of Asia Pacific),Latin America (Brazil, Argentina, Colombia, and Rest of L.A.), Middle East and Africa (Turkey, GCC, UAE and South Africa Rest of Middle East).
Results of the recent scientific undertakings towards the development have been studied. Nevertheless, the factors affecting the leading industry players to adopt synthetic sourcing of the market products have also been studied in this statistical surveying report. As per the report, Nanomedicine market revenue in the year 2020 was USD XX million and is expected to reach USD XX million in the year 2028 at XX% CAGR. It describes current changing market trends to help our clients make astute decisions accordingly. We are also ready to serve with a customized report. According to the need of the clients, this report can be customized and available in a separate report for the specific region.
**NOTE:Our analysts monitoring the situation across the globe explains that the market will generate remunerative prospects for producers to post the COVID-19 crisis.
Report Focus:
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Secondary Data Sources That We Refer To:
Annual reports, investor presentations, SEC filings, and press releases of companies operating in the market.Website, reports, and press releases of end-user facilities.
Secondary Research Is Conducted To Derive The Following Information:
Details such as revenues, market share, strategies, growth rate, product & their pricing by region/country for all major companiesNumber of procedures and an average price of proceduresReplacement rate and pricing of capital equipmentMarket dynamics in relation to the market under focus Drivers, restraints, trends, and opportunitiesMarket & technological trends, new product developments, product pipeline
COVID-19 Impact on Global Nanomedicine Market
The market report analyses the impact of Coronavirus (COVID-19) on the industry. Since the COVID-19 virus outbreak in December 2020, the disease has spread to almost 180+ countries around the globe with the World Health Organization declaring it a public health emergency.
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Key trends that will shape the future of Nanomedicine Market to 2027 | GE Healthcare, Johnson & Johnson, Mallinckrodt plc The Courier - The...
Researchers in the cancer nanomedicine community debate whether use of nanoparticles can best deliver drug therapy to tumors passively by adding a targeted anti-cancer molecule to bind to specific cancer cell receptor and, in theory, keep the nanoparticle in the tumor longer.
According to a study published in Science Advances, new research on tumors by investigators at the Johns Hopkins Kimmel Cancer Center suggest that the question is more complicated. Laboratory testing of 5 human cancer cell lines with 3 variants of the immune system found that nanoparticles coated with trastuzumab, a drug that targets human epidermal growth factor receptor 2 (HER2)-positive breast cancer cells, were better retained in the tumors than plain nanoparticles, even in tumors that did not express the pro-growth HER2 protein.
However, immune cells of the host exposed to nanoparticles induced an anti-cancer immune response by activating T cells that invaded and slowed tumor growth.
Its been known for a long time that nanoparticles, when injected into the bloodstream, are picked up a scavenger-like macrophages and other immune system cells, said senior study author Robert Ikov, PhD, MSc. Many researchers in the field have been focused on trying to reduce interaction with immune cells, because they have been trying to increase the circulation time of the nanoparticles and their retention in tumor cells. But our study demonstrates that the immune cells in the tumor collect and react to the particles in such a way to stimulate an anti-cancer response. This may hold potential for advancing beyond drug delivery toward developing cancer immunotherapies.
The researchers conducted in vitro experiments by applying some plain starch-coated iron oxide nanoparticles and others coated with trastuzumab to 5 human breast cancer cell lines. They found that the amount of binding between the trastuzumab-coated nanoparticles and cells depended on how much the cancer cells expressed the oncogene HER2. In patients, HER-positive breast cancers are among the most resistant to standard chemotherapy. Trastuzumab (Herceptin, Genentech) targets HER2-postive tumor cells and triggers the immune system as well.
Researchers had previously suspected that animals immune systems were interacting strongly with the nanoparticles and playing a role in determining retention of the particles in the tumor, whether or not a drug was added. Experiments revealed that tumor-associated immune cells were responsible for collecting the nanoparticles and that cell lines with an intact immune system retained more of the trastuzumab-coated nanoparticles than those without.
In addition, inflammatory immune cells in the tumors immediate surroundings seized more of the coated nanoparticles than the plain ones, according to the study. Finally, in a series of 30-day experiments, the researchers found that exposure to nanoparticles inhibited tumor growth 3 to 5 times more than controls, and increased CD8-positive cancer-killing T cells in the tumors.
The anti-cancer immune activating response was equally effective with exposure to either plain or trastuzumab-coated nanoparticles. The investigators said that this demonstrated that systemic exposure to nanoparticles can cause a systemic host immune response that leads to anti-cancer immune stimulation and does not require nanoparticles to be inside the tumors.
The work suggests that complex interdependencies exist between the host and tumor immune responses to nanoparticle exposure. These results offer possibilities for exploring nanoparticle targeting of the tumor immune microenvironment and demonstrate exciting new potential to develop nanoparticles as platforms for cancer immune therapies, according to the study.
The investigators next plan to study whether the same types of immune responses can be generated for noncancer conditions, such as infectious diseases.
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Study Reveals Nanoparticle Therapy Delivery in Breast Cancer - Pharmacy Times
New Jersey, United States: Market Research Intellect has added a new research report titled, Healthcare Nanotechnology (Nanomedicine) Market Professional Survey Report 2020 to its vast collection of research reports. The Healthcare Nanotechnology (Nanomedicine) market is expected to grow positively for the next five years 2020-2026.
The Healthcare Nanotechnology (Nanomedicine) market report studies past factors that helped the market to grow as well as, the ones hampering the market potential. This report also presents facts on historical data from 2011 to 2019 and forecasts until 2026, which makes it a valuable source of information for all the individuals and industries around the world. This report gives relevant market information in readily accessible documents with clearly presented graphs and statistics. This report also includes views of various industry executives, analysts, consultants, and marketing, sales, and product managers.
Key Players Mentioned in the Healthcare Nanotechnology (Nanomedicine) Market Research Report:
Market Segment as follows:
The global Healthcare Nanotechnology (Nanomedicine) Market report highly focuses on key industry players to identify the potential growth opportunities, along with the increased marketing activities is projected to accelerate market growth throughout the forecast period. Additionally, the market is expected to grow immensely throughout the forecast period owing to some primary factors fuelling the growth of this global market. Finally, the report provides detailed profile and data information analysis of leading Healthcare Nanotechnology (Nanomedicine) company.
Healthcare Nanotechnology (Nanomedicine) Market by Regional Segments:
The chapter on regional segmentation describes the regional aspects of the Healthcare Nanotechnology (Nanomedicine) market. This chapter explains the regulatory framework that is expected to affect the entire market. It illuminates the political scenario of the market and anticipates its impact on the market for Healthcare Nanotechnology (Nanomedicine) .
The Healthcare Nanotechnology (Nanomedicine) Market research presents a study by combining primary as well as secondary research. The report gives insights on the key factors concerned with generating and limiting Healthcare Nanotechnology (Nanomedicine) market growth. Additionally, the report also studies competitive developments, such as mergers and acquisitions, new partnerships, new contracts, and new product developments in the global Healthcare Nanotechnology (Nanomedicine) market. The past trends and future prospects included in this report makes it highly comprehensible for the analysis of the market. Moreover, The latest trends, product portfolio, demographics, geographical segmentation, and regulatory framework of the Healthcare Nanotechnology (Nanomedicine) market have also been included in the study.
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Table of Content
1 Introduction of Healthcare Nanotechnology (Nanomedicine) Market1.1 Overview of the Market1.2 Scope of Report1.3 Assumptions
2 Executive Summary
3 Research Methodology3.1 Data Mining3.2 Validation3.3 Primary Interviews3.4 List of Data Sources
4 Healthcare Nanotechnology (Nanomedicine) Market Outlook4.1 Overview4.2 Market Dynamics4.2.1 Drivers4.2.2 Restraints4.2.3 Opportunities4.3 Porters Five Force Model4.4 Value Chain Analysis
5 Healthcare Nanotechnology (Nanomedicine) Market, By Deployment Model5.1 Overview
6 Healthcare Nanotechnology (Nanomedicine) Market, By Solution6.1 Overview
7 Healthcare Nanotechnology (Nanomedicine) Market, By Vertical7.1 Overview
8 Healthcare Nanotechnology (Nanomedicine) Market, By Geography8.1 Overview8.2 North America8.2.1 U.S.8.2.2 Canada8.2.3 Mexico8.3 Europe8.3.1 Germany8.3.2 U.K.8.3.3 France8.3.4 Rest of Europe8.4 Asia Pacific8.4.1 China8.4.2 Japan8.4.3 India8.4.4 Rest of Asia Pacific8.5 Rest of the World8.5.1 Latin America8.5.2 Middle East
9 Healthcare Nanotechnology (Nanomedicine) Market Competitive Landscape9.1 Overview9.2 Company Market Ranking9.3 Key Development Strategies
10 Company Profiles10.1.1 Overview10.1.2 Financial Performance10.1.3 Product Outlook10.1.4 Key Developments
11 Appendix11.1 Related Research
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Tags: Healthcare Nanotechnology (Nanomedicine) Market Size, Healthcare Nanotechnology (Nanomedicine) Market Growth, Healthcare Nanotechnology (Nanomedicine) Market Forecast, Healthcare Nanotechnology (Nanomedicine) Market Analysis, Healthcare Nanotechnology (Nanomedicine) Market Trends, Healthcare Nanotechnology (Nanomedicine) Market
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Healthcare Nanotechnology (Nanomedicine) Market Size Analysis, Top Manufacturers, Shares, Growth Opportunities and Forecast to 2026 - Science In Me
Elisabeth Bik, the microbiologist and research integrity consultant noted for unearthing evidence of research misconduct, tweeted on February 21that she and some others had uncovered over 400 scientific papers that all share a very similar title layout, graph layout, and (most importantly) the same Western blot layout indicating an organised web of potential fraud. She also expressed concern that there might be hundreds of papers more, and that she and her collaborators may just have spotted the obviously fraudulent ones.
Western blotting is a technique that microbiologists employ to identify the proteins present in a tissue sample. As an analytical technique involving real-world materials, no two images of western blots are supposed to look alike, and similarities suggest the image may have been manipulated, inadvertently or otherwise.
Guided by this and similar giveaways, Bik, @SmutClyde, @mortenoxe and @TigerBB8 (all Twitter handles of unidentified persons), report as written by Bik in ablog post that the Western blot bands in all 400+ papers are all very regularly spaced and have a smooth appearance in the shape of a dumbbell or tadpole, without any of the usual smudges or stains. All bands are placed on similar looking backgrounds, suggesting they were copy-pasted from other sources or computer generated.
Bik also notes that most of the papers, though not all, were published in only six journals: Artificial Cells Nanomedicine and Biotechnology,Journal of Cellular Biochemistry,Biomedicine & Pharmacotherapy,Experimental and Molecular Pathology,Journal of Cellular Physiology, andCellular Physiology and Biochemistry, all maintained reputed publishers and importantly all of them peer-reviewed.
As a result, the discovery of the problem papers has prompted concerns about the ability of peer-review to check research misconduct in the scientific community.
Indeed, when Bik writes, Finding these fabricated images should not rely solely on the work of unpaid volunteers, she evidently means herself and her collaborators but her words also apply to peer-reviewers, who are unpaid for their work and often lack both the resources and the inclination to investigate each paper in close detail. As a result, peer-review is often not the insurmountable defence some proclaim it to be, nor are peer-reviewed journals as free of bogus science as they claim to be.
As Madhusudhan Raman, a postdoctoral scholar at the Tata Institute of Fundamental Research, Mumbai,wrote inThe Wire, any attempt to radically change the nature of peer-review must necessarily be accompanied by a change in the way the referees are compensated for their time and effort, especially within academia.
A PubPeer user who goes by Indigofera Tanganyikensis first identified the problem in two papers (thisandthis) both published by Chinese researchers. On February 17 this year, a little under a week before Bik published her blog post, two American researchers Jennifer A. Byrne and Jana Christopher published an articlediscussing similar research misconduct based on 17 papers they had discovered.
According to Bik, As it turns out, Byrne and Christophers publication describes the exact same set of papers that our small team of image forensics detectives had been working on in the past month.
These sleuths, as @SmutClydewrote on Leonid Schneiders blog, believe they have stumbled upon at least one paper mill. To quote (selectively) from Biks post,
A paper mill is a shady company that produces scientific papers on demand. They sell these papers to [people] who do not have any time in their educational program to actually do research. Authorships on ready-to-submit or already-accepted papers are sold to medical students for hefty amounts. Whether or not the experiments described in these papers has actually been performed is not clear. Some of these paper mills might have laboratories producing actual images or results, but such images might be sold to multiple authors to represent different experiments. Thus, the data included in these papers is often falsified or fabricated.
The mills seem to have been hired by Chinese clinicians affiliated to various medical colleges and hospitals in China (234 of the 400+ papers have been authored by people affiliated to institutions in Shandong province). The papers were all published between 2016 and 2020. @SmutClyde wrote that after they publicised their findings, including thedataset of papers they had identified as potentially fraudulent (and which they continue to update), an author of one of the papers wrote in:
Being as low as grains of dust of the world, countless junior doctors, including those younger [than] me, look down upon the act of faking papers. But the system in China is just like that, you cant really fight against it. Without papers, you dont get promotion; without a promotion, you can hardly feed your family. I also want to have some time to do scientific research, but its impossible. During the day, I have outpatient surgeries; after work, I have to take care of my kids. I have only a little bit time to myself after 10 pm, but this is far from being enough because scientific research demands big trunks of time. The current environment in China is like that.
Considering how the peer-review of all of those journals have failed, what the detectives have found effectively represents a large volume of unscientific data entering the scientific literature, funnelled predominantly by Chinese researchers who probably hired a paper mill to help meet the publishing requirements set by their respective institutions. Bik wrote that it is of great concern to see that this specific paper mill has successfully infected particular journals and that it is very alarming to see that journal editors do not appear to have noticed the similarities between dozens of papers published in their journals.
This said, the note from the unnamed Chinese author indicates the source of the problem is hardly new or even confined to China.
For example, until Prakash Javadekar, then the Union human resource development minister, said in mid-2017 that college teachers would not be required to undertake research to qualify for promotions, people who had not trained for research and have since been embedded in environments not properly equipped to support research were forced to conduct research, and publish papers.
Javadekar is to be loudly applauded and congratulated for taking this measure,Pushkar wrote forThe Wireat the time. The research requirement in the [Academic Performance Indicators] for college teachers was a travesty. All that it achieved was a proliferation of fake journals for college teachers to publish in.
Indeed, India has come to be known the fake journals capital of the world, partly as a result of requiring people who cannot undertake research to undertake research, and partly because research productivity has become one of the core measures of determining whether a country is a scientific superpower.
For another example, the journalNaturereportedthat Pakistans research output increased the most among all countries in the world by 21% in 2018, a feat that it dubbed a phenomenal success. However, as Anjum Altaf, former provost of Karachis Habib University and a famous teacher, subsequentlytoldThe Wire, The volume of third-rate publications in Pakistan has increased greatly simply because [Pakistans Higher Education Commission] introduced a tenure-track system and required publications for promotion.
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Sleuths Uncover Web of Research Fraud in 400+ Papers From China - The Wire
Healthcare Nanotechnology (Nanomedicine) Market report is to provide accurate and strategic analysis of the Profile Projectors industry. The report closely examines each segment and its sub-segmehnt futures before looking at the 360-degree view of the market mentioned above. Market forecasts will provide deep insight into industry parameters by accessing growth, consumption, upcoming market trends and various price fluctuations.
Global Healthcare Nanotechnology (Nanomedicine) Market research reports growth rates and market value based on market dynamics, growth factors. Complete knowledge is based on the latest innovations in the industry, opportunities and trends. In addition to SWOT analysis by key suppliers, the report contains a comprehensive market analysis and major players landscape.
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The report on the Global Healthcare Nanotechnology (Nanomedicine) Market has newly added by The Insight Partners to its huge repository. The market is expected to increase by the end of forecast period. Primary and secondary research methodologies have been used for curating this research report.
The global regions which are scrutinized for a clear understanding of Global Healthcare Nanotechnology (Nanomedicine) Market are North America, Latin America, Asia-Pacific, Africa, Europe, and India. The research on the Global Healthcare Nanotechnology (Nanomedicine) Market will be applicable to investors, business owners, industry experts, and various c level peoples. Profiling of the several top-level industries has been included in this informative report.
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Healthcare Nanotechnology (Nanomedicine) Market Forecast to 2027 with Key Companies Profile, Supply, Demand and SWOT Analysis - Jewish Life News
Newest Learn about at the International Nanomedicine Market
The lately printed record via Transparency Market Analysis at the world Nanomedicine marketplace provides resourceful insights referring to the long run possibilities of the Nanomedicine marketplace. The underlying developments, enlargement alternatives, impeding elements, and evident marketplace drivers are totally studied within the introduced record.
As in keeping with the record, the worldwide Nanomedicine marketplace is projected to develop at a CAGR of ~XX% and exceed the worth of ~US$ against the tip of 2029. Additionally, an in-intensity research of the micro and macro-financial elements which are expected to steer the trajectory of the Nanomedicine marketplace all through the forecast length (2019-2029) is integrated within the record.
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Important Insights Associated with the Nanomedicine Market within the Document:
Nanomedicine Market Segments
A radical analysis of the long run possibilities of the Nanomedicine marketplace throughout more than a few areas is tracked within the record.
segmentation, and demanding situations out there were mentioned at duration within the analysis record.
Review of the Cloud Computing Market in Healthcare Trade
As in keeping with the analysis record, the worldwide marketplace for cloud computing within the healthcare business used to be valued at US$1.82 bn in 2011 and is projected to succeed in a worth of US$6.79 bn via the tip of 2018. The marketplace is projected to sign up a exceptional 21.30% CAGR between 2012 and 2018.
The safety of get entry to and knowledge integrity and several other different advantages presented via cloud computing are estimated to inspire the expansion of the marketplace in the following couple of years. Alternatively, information leakage considerations, information integration and consistency, and knowledge relocation are one of the key elements estimated to restrain the expansion of the worldwide cloud computing marketplace within the healthcare business in the following couple of years.
At the moment, the instrument-as-a-provider phase leads the worldwide cloud computing marketplace within the healthcare business. However, the platform-as-a-provider phase is estimated to witness considerable enlargement within the coming years. Moreover, at the foundation of finish use, the non-scientific knowledge techniques marketplace is projected to guide the worldwide marketplace within the close to long run.
A number of the key geographical segments, North The usa is estimated develop at a swift tempo and account for an enormous proportion within the world marketplace for cloud computing within the healthcare business in the following couple of years. The top enlargement of this area may also be attributed to the presence of numerous biopharmaceutical gamers. As well as, the emerging focal point on analysis and construction actions is anticipated to give a contribution widely against the expansion of the marketplace.
Firms Discussed within the Analysis Document
The world marketplace for cloud computing within the healthcare business is very fragmented in nature as no key gamers grasp greater than a proportion of 10% out there at this time. CareCloud, ClearDATA Networks, Oracle Company, Microsoft, Agfa Healthcare, IBM Company, and Merge Healthcare are one of the key gamers running within the world cloud computing marketplace within the healthcare business.
Key Segments of the International Cloud Computing marketplace in Healthcare Trade
International Cloud Computing marketplace in Healthcare Trade, via provider fashions
International Cloud Computing marketplace in Healthcare Trade, via pricing fashions
International Cloud Computing marketplace in Healthcare Trade, via finish customers
International Cloud Computing marketplace in Healthcare Trade, via Geography
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Clene Nanomedicines remyelination therapy candidate, CNM-Au8, showed a robust ability to stimulate the production of new myelin and increase the number of myelin-wrapped nerve fibers in the brain and spinal cord of animals in models of demyelinating disease, allowing mice to recover motor skills, a study reports.
Such preclinical data support the efficacy of this potential treatment, now being tested in clinical trials with multiple sclerosis (MS) patients.
These early findings were reported in the study Nanocatalytic activity of clean-surfaced, faceted nanocrystalline gold enhances remyelination in animal models of multiple sclerosis, published in the journalNature Scientific Reports.
In MS, the immune system attacks myelin, the protective sheath around nerve fibers or axons. Myelin is essential for the fast transmission of electrical signals between neurons, and its loss (demyelination) damages the integrity of nerve cells and their ability to communicate with each other.
Finding therapies that promote remyelination the recovery of myelin is a high priority for MS, the researchers noted.Such treatments could potentially repair demyelinating lesions in the central nervous system (the brain and spinal cord), restoring function to nerve cells affected by the disease.
Most approved MS therapies dampen the immune systems activity to prevent further myelin damage. However, they cannot undo existing damage or replace the myelin sheaths that have been lost.
Clene Nanomedicines lead compound, CNM-Au8, is a potential remyelination therapy for MS and other neurodegenerative disorders, including Parkinsons disease, and amyotrophic lateral sclerosis (ALS).
CNM-Au8 is a solution of gold (Au) nanoparticles with apatented crystal structure, named a clean-surfaced nanocrystal (CSN). According to the company, these nanocrystals have properties that make them highly biologically active, allowing them to facilitate certain energy-related reactions within cells.
In the brain, both neurons and supporting cells, includingoligodendrocytesthat produce myelin, need substantial amounts of energy to work. In fact, the brain consumes more than 25% of the bodys metabolic resources in order to sustain the efficient flux of information through its vast network of nerve fibers.
CNM-Au8 is expected to enhance key metabolic reactions in neurons and oligodendrocytes so to increase energy reserves within these cells, while decreasing the harmful molecules naturally generated by the cells metabolism. This process, which Clene calls nanocatalysis, is thought to improve the survival and function of neurons, and to support the ability of oligodendrocytes to create new myelin.
CNM-Au8 has demonstrated a good safety profile in Phase 1 studies in healthy volunteers, and preclinical studies in animal models of MS and other diseasesindicate the therapyhas both remyelination and neuroprotection effects.
Several ongoing Phase 2 trials are evaluating CNM-Au8 in neurodegenerative diseases, including two studies in people with non-active, relapsing MS.
REPAIR-MS (NCT03993171) is an open-label Phase 2 trial assessing the safety, pharmacokinetics (availability of the therapy in the body) and pharmacodynamics (its effects) of differing oral doses of CNM-Au8 in 24 adults with relapsing-remitting MS (RRMS). This study is currently enrolling eligible patients at theUniversity of Texas Southwestern. More details can be foundhere. It is expected to conclude in the fall.
Another Phase 2 trial, called VISIONARY-MS (NCT03536559), is investigating the efficacy and safety of CNM-Au8 in up to 150 adults with RRMS, who have chronic vision problems due to lesions (chronic optic neuropathy). This study is also recruiting at nine sites across Australia, and is supported by the National Multiple Sclerosis Society. Contact and site information is available here. Results from VISIONARY-MS are expected in 2021.
Now, the preclinical work by researchers at Clene Nanomedicine, Northwestern University, and George Washington Universityprovides additional evidence supporting the ability of these gold nanocrystalsto promote remyelination in cell and animal models of MS.
We are gratified at the publication of these data. These results establish the rationale for our ongoing Phase 2 clinical trial, VISIONARY-MS, which is designed to demonstrate the efficacy of CNM-Au8 for the treatment of chronic optic neuropathy in patients with non-active relapsing MS, Robert Glanzman, MD, chief medical officer of Clene Nanomedicine, said in a press release.
Researchers found that oral delivery of CNM-Au8 to mice and rat models of demyelination led to robust remyelination activity in the brain and spinal cord, leading to higher numbers of myelin-wrapped axons. Study data also showed that CNM-Au8 resulted in a greater migration of oligodendrocytes to lesion sites, and increased myelin production.
The remyelination promoted by CNM-Au8 was also matched by a significant recovery of physical abilities in the mice, evaluated using different locomotor and fine motor tests.
Working on cells in lab dishes, known as in vitro assays, the scientists showed that treating oligodendrocyte precursor cells with CNM-Au8 stimulated their differentiation and maturation, and the expression of myelin-related markers.
The gold nanocrystals were seen to act via a novel energy metabolism pathway that speeds the conversion of NADH to NAD+, a critical factor for sensing and producing energy in cells. CNM-Au8 also increased the levels of adenosine triphosphate (ATP), a small molecule used as fuel by cells, and turned on genes related to myelin production, collectively resulting in functional myelin generation, the researchers reported.
These results further validate our entirely new approach using therapeutic gold nanocatalysts as a mechanism to support the cellular viability and enhanced function of neurons and oligodendrocytes, saidKaren Ho, PhD, one of the studys authors and director of Translational Medicine at Clene Nanomedicine.
CNM-Au8 is one of a limited number of drugs being developed which have demonstrated remyelination capabilities. We believe these data exemplify a strong step forward in the development of a treatment to improve function in the lives of more than one million people living with MS in the U.S., Ho concluded.
Ana is a molecular biologist with a passion for discovery and communication. As a science writer, she looks for connecting the public, in particular patients and healthcare providers, with clear and quality information about the latest medical advances. Ana holds a Ph.D. in Biomedical Sciences from the University of Lisbon, Portugal, where she specialized in infectious diseases, epigenetics, and gene expression.
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Patrcia holds her PhD in Medical Microbiology and Infectious Diseases from the Leiden University Medical Center in Leiden, The Netherlands. She has studied Applied Biology at Universidade do Minho and was a postdoctoral research fellow at Instituto de Medicina Molecular in Lisbon, Portugal. Her work has been focused on molecular genetic traits of infectious agents such as viruses and parasites.
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Remyelination Potential of MS Therapy in Phase 2 Testing Evident in Animal Work, Study Says - Multiple Sclerosis News Today
Annual Report: CIBBIM Nanomedicine
The area studies the use of nanotechnology in biomedical applications mainly with two purposes: first, to improve therapeutic strategies and second, to impro...
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Annual Report: CIBBIM Nanomedicine - Video
Fatima Aouidat,1 Sarah Boumati,2 Memona Khan,1 Frederik Tielens,3 Bich-Thuy Doan,2 Jolanda Spadavecchia1
1CNRS, UMR 7244, CSPBAT, Laboratory of Chemistry, Structures and Properties of Biomaterials And Therapeutic Agents University Paris 13, Sorbonne Paris Cit, Bobigny, France; 2UTCBS Chimie ParisTech University Paris Descartes - CNRS UMR 8258 INSERM U1022 Equipe Synthesis, Electrochemistry, Imaging and Analytical Systems for Diagnostics SEISAD, Paris, France; 3General Chemistry (ALGC), Vrije University of Brussel (Free University Brussels-VUB), Brussel, Belgium
Correspondence: Jolanda Spadavecchia Email jolanda.spadavecchia@univ-paris13.fr
Introduction: The development of biopolymers for the synthesis of Gd(III) nanoparticles, as therapeutics, could play a key role in nanomedicine. Biocompatible polymers are not only used for complex monovalent biomolecules, but also for the realization of multivalent active targeting materials as diagnostic and/or therapeutic hybrid nanoparticles. In this article, it was reported for the first time, a novel synthesis of Gd(III)biopolymerAu(III) complex, acting as a key ingredient of core-shell gold nanoparticles (Gd(@AuNPs).Material and methods: The physical and chemical evaluation was carried out by spectroscopic analytical techniques (Raman spectroscopy, UV-visible and TEM). The theoretical characterization by DFT (density functional theory) analysis was carried out under specific conditions to investigate the interaction between the Au and the Gd precursors, during the first nucleation step. Magnetic features with relaxivity measurements at 7T were also performed as well as cytotoxicity studies on hepatocyte cell lines for biocompatibility studies. The in vivo detailed dynamic biodistribution studies in mice to characterize the potential applications for biology as MRI contrast agents were then achieved.Results: Physicalchemical evaluation confirms the successful design and reaction supposed. Viabilities of TIB-75 (hepatocytes) cells were evaluated using Alamar blue cytotoxic tests with increasing concentrations of nanoparticles. In vivo biodistribution studies were then accomplished to assess the kinetic behavior of the nanoparticles in mice and characterize their stealthiness property after intravenous injection.Conclusion: We demonstrated that Gd@AuNPs have some advantages to display hepatocytes in the liver. Particularly, these nanoconjugates give a good cellular uptake of several quantities of Gd@NPs into cells, while preserving a T1 contrast inside cells that provide a robust in vivo detection using T1-weighted MR images. These results will strengthen the role of gadolinium as complex to gold in order to tune Gd(@AuNPs) as an innovative diagnostic agent in the field of nanomedicine.
Keywords: Gd-gold complex, theoretical study, MRI, relaxivity, biodistribution
This work is published and licensed by Dove Medical Press Limited. The full terms of this license are available at https://www.dovepress.com/terms.php and incorporate the Creative Commons Attribution - Non Commercial (unported, v3.0) License.By accessing the work you hereby accept the Terms. Non-commercial uses of the work are permitted without any further permission from Dove Medical Press Limited, provided the work is properly attributed. For permission for commercial use of this work, please see paragraphs 4.2 and 5 of our Terms.
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Nanomedicine: towards development of patient-friendly drug-delivery systems
ES-Cancer Focus Group. Third Journal Club: Nanomedicine: towards development of patient-friendly drug-delivery systems for oncological applications.
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Ideas @Davos | Sonia Trigueros | Breakthroughs in Nanomedicine
http://www.weforum.org/ Growing tolerance to antibiotics means that there are more people dying of infection than cancer. Breakthrough discoveries in nanomed...
By: World Economic Forum
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Ideas @Davos | Sonia Trigueros | Breakthroughs in Nanomedicine - Video