Global Stem Cells Group to Host the First International Symposium on Stem Cells and Regenerative Medicine in Buenos …

Posted on by

Miami (PRWEB) May 30, 2014

GlobalStemCellsGroup.com will host the First International Symposium on Stem Cell Research in Buenos Aires, Argentina Oct. 2, 3 and 4. The symposium will provide an opportunity to showcase advancements in stem cell research and therapies on a global level and establish a dialogue among the worlds leading stem cell experts. Pioneers and luminaries in stem cell medicine will be featured speakers as well as accomplished guests prepared to share their knowledge and experience in their individual medical specialties.

Regenerative medicine as a field is still in its infancy, and Global Stem Cells Group President and CEO Benito Novas believes it is time to clear up old misconceptions and change outdated attitudes by educating people on the wide range of illnesses and injuries stem cell therapies are already treating and curing. The first step, Novas says, is establishing a dialogue between researchers and practitioners in order to move stem cell therapies from the lab to the physicians office.

Our objective is to open a dialogue among the worlds medical and scientific communities in order to advance stem cell technologies and translate them into point-of-care medical practices, Novas says. Our mission is to bring the benefits of stem cell therapies to the physicians office for the benefit and convenience of the patient, safely and in full compliance with the highest standard of care the world has to offer.

An interdisciplinary team of leading international stem cell experts will provide a full day of high-level scientific lectures aimed at medical professionals.

Among the growing list of speakers are some of the worlds most prominent authorities on stem cell medicine including:

The objective of Global Stem Cell Groups international symposium is to educate the public and the medical community, and at the same time establish a dialog between physicians, scientists, biotech companies and regulatory agencies in order to advance stem cell technologies so they can be used to benefit people who need them.

Global Stem Cells Group is also joining forces with some of the most prestigious regenerative medicine conferences in South America including:

Stem cell therapies are revolutionizing the anti-aging aesthetics industry while offering new hope for sufferers of serious chronic debilitating diseases

For more information on the Global Stem Cell Group First International Symposium on Stem Cells and Regenerative Medicine and the events lineup of speakers, visit the Global Stem Cells Symposium website, email bnovas(at)regenestem(dot)com, or call 305-224-1858.

Follow this link:
Global Stem Cells Group to Host the First International Symposium on Stem Cells and Regenerative Medicine in Buenos ...

Engineered Food

Posted on by

Humans have been manipulating crop genetics for thousands of years, crossing and selecting plants that exhibit desirable traits. In the last century, breeders exposed crops to radiation and chemicals that induced random mutations. These and other lab methods gave fruits and vegetables new colors, made crops disease resistant and made grains easier to harvest. Most wheat, rice and barley are descendants of mutant varieties, as are many vegetables and fruits. Hello, Star Ruby grapefruit! In the early 1980s, scientists discovered how to insert genes from other species into plants. The process led to the 1994 commercialization of the first GMO, the Flavr Savr tomato. It was tasteless and was pulled from the market. No GMO meat is currently for sale, though not for lack of trying. AquaBounty Technologies has been trying for 19 years to win approval for salmon engineered to grow twice as fast as conventional salmon, with less feed. The 1995 application remains pending before the U.S. Food and Drug Administration, which has determined the fish is safe to consume. Advocates want it labeled.

Read more here:
Engineered Food

DNA-binding fluorescent dyes detect real-time cell toxicity during drug screening

Posted on by

PUBLIC RELEASE DATE:

30-May-2014

Contact: Vicki Cohn vcohn@liebertpub.com 914-740-2100 x2156 Mary Ann Liebert, Inc./Genetic Engineering News

New Rochelle, NY, May 30, 2014High throughput screening of compounds in live cells is a powerful approach for discovering new drugs, but the potential for cell toxicity must be considered. A novel technique that uses DNA-binding fluorescent dyes to evaluate the cytotoxicity of an experimental compound in real-time during screening, saving time and resources, is described in ASSAY and Drug Development Technologies, a peer-reviewed journal from Mary Ann Liebert, Inc., publishers. The article is available on the ASSAY and Drug Development Technologies website.

Lucius Chiaraviglio and James Kirby, Beth Israel Deaconess Medical Center, evaluated 19 fluorescent DNA-binding dyes and identified four dyes that were not harmful to cells and could not cross the cell membrane if a cell was viable. The authors demonstrated the ability to use these dyes to detect cell death during drug screening in the article "Evaluation of Impermeant, DNA-Binding Dye Fluorescence as a Real-Time Readout of Eukaryotic Cell Toxicity in a High Throughput Screening Format."

###

About the Journal

Assay and Drug Development Technologies is an authoritative peer-reviewed journal published 10 times a year in print and online. It provides early-stage screening techniques and tools that enable identification and optimization of novel targets and lead compounds for new drug development. Complete tables of content and a complementary sample issue may be viewed on the ASSAY and Drug Development Technologies website.

About the Publisher

Mary Ann Liebert, Inc., publishers, is a privately held, fully integrated media company known for establishing authoritative peer-reviewed journals in many areas of science and biomedical research, including OMICS: A Journal of Integrative Biology and Genetic Testing and Molecular Biomarkers. Its biotechnology trade magazine, Genetic Engineering & Biotechnology News (GEN), was the first in its field and is today the industry's most widely read publication worldwide. A complete list of the firm's 80 journals, books, and newsmagazines is available on the Mary Ann Liebert, Inc., publishers website.

More:
DNA-binding fluorescent dyes detect real-time cell toxicity during drug screening

Virus that helped eradicate smallpox takes on cancer in startups dual-mechanism immunotherapy

Posted on by

With a little genetic engineering, the vaccine that was key in helping eradicate smallpox more than 30 years ago could also be key in curing cancer, if a young Cleveland biotech has anything to say about it.

Western Oncolytics is developing a dual-mechanism therapy that combines oncolytic virus and gene therapy technologies with the hope of wiping out the ability of cancer cells to survive in the body.

CEO Kurt Rote is a first-time entrepreneur, but you wouldnt know it from talking to him. After getting a biomedical engineering degree from Duke and moving to Switzerland to get an MBA, he worked for a short time at a small biotech firm before deciding to risk everything to realize a personal dream of curing cancer.

In pursuit of bleeding-edge technology, he started making calls to university researchers.I went down a list of NIH grants and talked to as many of them as possible, he said. I wanted to go where the science led me.

Where it led him was to the office of Stephen H. Thorne at the University of Pittsburgh Cancer Center, who had been studying oncolytic viruses for years.

Oncolytic viruses are genetically modified to infect and kill cancer cells while simultaneously triggering an anti-tumor immune response. Their promise lies in being able to treat cancers with side effects that parallel those of a flu shot, rather than those from chemotherapy.

Although theyve been studied for decades, theyre just now advancing to the point where theyre being tested in large-scale human trials. Amgen recently completed a Phase 3 study in melanoma patients of an oncolytic virus it bought from Biovex in a 2011 deal worth up to $1 billion. The results of the trial were mixed, potentially limiting the commercial viability of the drug, but the trial serves as an important milestone for the field.

The therapy developed in Thornes lab employs similar concepts but is based on more advanced technology and has shown better tumor shrinkage and remission in animal testing, Rote said.

A number of different elements work together in the vaccine. It contains the vaccinia virus (used in the smallpox vaccine) with three gene modifications: the addition of two that signal T-cells to come to the tumor and reduce the number of immune suppressor cells in the tumor, respectively, and the deletion of a viral gene which leads to infected cells sending more signals to the immune system.

And, to avoid the immune system from being triggered immediately, before the virus reaches the tumor, scientists have modified its surface to delay the immune response.

Visit link:
Virus that helped eradicate smallpox takes on cancer in startups dual-mechanism immunotherapy

Garden City showcases science at annual symposium

Posted on by

On Tuesday, May 27, Garden City High hosted an array of student research projects at its annual Science Symposium - the culmination of students' work throughout the school year. Dr. Steven Gordon, Garden City's science research coordinator, says the national focus on S.T.E.M. (science, technology, engineering and mathematics) has spurred more interest in science, and higher achievements. He explained the role of research from Garden City on up.

"The science research program is important in preparing students for STEM careers - it's very useful. We hear this from students who've gone off to college, and we learn how accelerated our students were compared to their peers in college. Many of our current students entered their work in local, regional, and national competitions. This is their opportunity to present to parents, other students who might be interested in the program, and the larger Garden City community," Gordon said.

Dr. Gordon noted that 87 high school students participated with projects, the highest number ever for the district. With such high student involvement parents were enthusiastic about seeing the presentations as well, as about 200 people including the school administration were in attendance. Garden City's school board also witnessed the district's latest science research, as Board President Barbara Trapasso, Vice President Angela Heineman and Board Member Robert Martin attended and applauded the work on display. Statistical data, published scholarly articles, and bio-medical graphics lined the high school library from wall to wall with each project.

According to Gordon, many of the projects students completed this year were done at the high school. In previous years the science research program had a lot of projects conducted at outside laboratories.

"We still have those going on, but we're doing a lot more in-house research now," he said.

Dr. Elena Cascio, Garden City's science curriculum coordinator for grades 6 through 12, said she was impressed with the variety of projects the students selected for research this year. The opportunity to dive in-depth into science created a wide playing field.

"Every student at every level and with every interest will find something to do. We saw behavioral projects, genetics, physics, and engineering - from the highest levels of sophistication to the very simple, everyday life functions. Parents were really engaged and asking questions about what the kids are doing," she said.

Cascio says that many students in high school science classes are unsure of the subject matter and what they want to learn in each class. As she has guided several students, she understood their individual learning curves. Some of the students that presented project Tuesday night were not accelerated in middle school classes. Cascio says the real value in Garden City's science research program is reaching the students who didn't feel connected to science until high school.

She believes D. Gordon's program changes things, and in general science research projects hold the potential to alter perspectives and become a driver of the students' ambitions.

"With research, they will be motivated to take other science courses such AP Environmental Science, AP Biology, or others that they would not even consider taking if there was no research program because they developed a new, personal interest now. They aren't just interested in science, they become advanced in science," Cascio said.

See the original post here:
Garden City showcases science at annual symposium

New Michael Todd True Organics Review by Health Writer Laura O'Connor Examines Knu Anti Aging Face Lift Serum

Posted on by

West Palm Beach, FL (PRWEB) May 30, 2014

Knu Anti Aging Face Lift Serum is a beauty product designed for both men and women with any skin type who are dealing with the challenges brought about by premature skin aging, including fine lines, puffy eyes, under eye circles, wrinkles, and dark circles.

The Michael Todd True Organics reviews online (most for the Knu Serum or Facelift Cream) and the large amount of hype surrounding the product line caught the attention of RequestedReview.coms Laura OConnor, prompting an investigative review.

While numerous companies boast of their products containing a single key ingredient, Michael Todd True Organics claim to have in fact created a product comprised of a combination of key natural age prevention ingredients including epidermal growth factor, snail serum, alpha hydroxyl acids and DMAE, fused with a combination of natural organic anti-aging ingredients, states OConnor.

Another interesting fact O'Connor discovered is that the product lives up to the line's name with a product formulation that is made with 70% percent organic ingredients, including jasmine, green tea, aloe vera, cranberry, essential oils whose purpose is to soothe, heal and provide antioxidant protection.

In her review of Knu Anti Aging Serum, O'Connor talks about the company background and philosophy as well as ingredients, reviews and results. The product is endorsed by Manhattans Eric Braverman, M.D., a prominent authority on anti-aging medicine who not only uses the product, but recommends it to his patients. Other celebrity endorsers for Knu Anti Aging Serum include Gillian Anderson, Jillian Barberie, and Tiffani Thiessen.

OConnor says the numerous celebrity endorsements are impressive because stars are very protective of who they allow to use their images and endorsements. She also likes how Michael Todd True Organics Knu Anti Aging Face Lift is not just all about organic ingredients but also about science and includes the latest anti-aging ingredients.

The entire Michael Todd Organics line follows this formula, comments O'Connor, Other popular Michael Todd products such as the Eyeosonic Duo and Damascus Rose Moisturizer, also don't contain added water, sulfates, parabens, synthetic fragrances, or artificial dye - and are not tested on animals, says OConnor.

In conclusion, O'Connor gives the whole Michael Todd skin care line and the Knu serum in particular her recommendation.

The Official The Michael Todd True Organics Website

Link:
New Michael Todd True Organics Review by Health Writer Laura O'Connor Examines Knu Anti Aging Face Lift Serum

Judith Crowell, M.D. trusted expert in cosmetic skincare treatments

Posted on by

Dr. Judith Crowell

People are living longer, healthier lives. With this positive trend comes an increase in the popularity and prevalence of anti-aging skincare products and cosmetic procedures. Spas, salons and cosmetic counters all offer products that promise the fountain of youth. Even nurses, general practitioners, gynecologists and dentists are joining the trend, performing Botox, Dysport and filler injections. But beware, says Judith Crowell, M.D.

These treatments should not be taken lightly, she explained. They are extremely effective when performed correctly, but can have terrible results when they are not.

Dr. Crowell is seeing more and more patients who are seeking her help to correct cosmetic procedures done elsewhere, which resulted in bumps under the eyes, puffy lips or drooping eyelids.

The bottom line: You are putting your appearance and possibly your health at risk when you go to someone who is not properly trained in the aesthetics and anatomy of the skin and muscles that are affected by Botox and injectable fillers, says Dr. Crowell. Your skin, after all, is your bodys largest organ. Who do you trust to help you take care of it?

A qualified doctor has studied what occurs in the aging face, Dr. Crowell said. It takes knowledge, skill, credentials and experience to combine the science and art necessary to achieve a beautiful and natural look.

Dr. Crowell is a Board-certified dermatologist with more than 20 years of experience in medical and aesthetic dermatology. She graduated from the University of Miami School of Medicine as a member of the Alpha Omega Alpha Honor Society and Iron Arrow Honor Society the highest honor that can be attained. Her internship in internal medicine was at Stanford University Hospital and her residency in dermatology was performed at the University of Pittsburgh School of Medicine. She completed her undergraduate studies at Boston University and graduated Magna Cum Laude.

Dr. Crowell is a Diplomate of the American Academy of Dermatology, a Fellow of the American Society of Dermatologic Surgery, adjunct professor at Barry Universitys Physician Assistant Program and a volunteer clinical associate professor at the University of Miami Department of Dermatology and Cutaneous Surgery. She has been recognized as one of Miamis Top Dermatologists by Castle Connolly Top Doctors for over a decade, and was specifically recognized as a top doctor in the field of cosmetic injectable fillers.

Dr. Crowell specializes in using various injectables and lasers to give her patients a refreshed, natural, younger-looking appearance. Its important to note that treatments are not one size fits all, she says.

Each injectable filler and each laser has a special purpose, and you need to know how to use them to achieve the best results, Dr. Crowell added.

See original here:
Judith Crowell, M.D. trusted expert in cosmetic skincare treatments

Researchers Identify New Genetic Building Blocks

Posted on by

Posted: Wednesday, May 28, 2014, 2:00 PM

WEDNESDAY, May 28, 2014 (HealthDay News) -- A team of international researchers has identified nearly 85 percent of proteins in the human body.

Proteins are the substances that provide structure, function and regulation of the body's tissues and organs. Human genes contain instructions (encoding) that direct the production of proteins, according to the U.S. National Institutes of Health.

In addition to finding the majority of the body's proteins, the researchers also identified 193 new proteins on the human genome. The proteins were found in areas of DNA that were believed to be "noncoding," or regions that do not encode proteins.

Finding proteins in areas with genes that weren't believed to code means the human genome could be more complex than previously believed, the researchers concluded.

"This was the most exciting part of this study, finding further complexities in the genome. The fact that 193 of the proteins came from DNA sequences predicted to be noncoding means that we don't fully understand how cells read DNA, because clearly those sequences do code for proteins," Dr. Akhilesh Pandey, a professor at the McKusick-Nathans Institute of Genetic Medicine and of biological chemistry, pathology and oncology at Johns Hopkins University in Baltimore, said in a news release.

More than 10 years ago, researchers identified all of the nearly 25,000 genes in human DNA. Known as the Human Genome Project, the research provided scientists with genetic information that helped them figure out how changes in certain genes could trigger some diseases.

The current researchers set out to create an initial catalog of all the proteins in the human body, or the human "proteome." The team identified proteins originating from more than 17,000 genes, which is about 84 percent of all of the genes in the human genome predicted to encode proteins.

Cataloging human proteins and where they can be found in the body may provide scientists even more insight than a catalog of all the genes in the human genome, the researchers pointed out. They explained that the characteristics of an organism depend on its genes. These genes, however, provide directions for making proteins, which are the building blocks of all cells in the body.

Read this article:
Researchers Identify New Genetic Building Blocks

UB spinoff Nanobiotix working to bring cancer treatment to market

Posted on by

Laurent Levy left UB in 1999 with a dream: transforming his recently completed postdoctoral research on nanomedicine into real-world products for patients battling cancer.

Today, the scientist-turned-entrepreneur is zeroing in on that goal.

In February, Levys drug development company, Nanobiotix, announced that a cancer treatment called NBTXR3, the first product from its NanoXray pipeline, had shown positive intermediate results in a pilot clinical trial on patients with advanced soft tissue sarcoma. These results allowed Nanobiotix to finalize and to announce its development plan for the launch of NBTXR3 on the market: With this first indication, advanced soft tissue sarcoma, NBTXR3 could be approved in Europe as early as 2016.

The news led to a jump in the companys stock price and new funding for research at UB.

Nanobiotix got its start in 2003 by licensing two technologies that Levy developed with colleagues at the university and Roswell Park Cancer Institute: magnetic nanoparticles for cancer treatment and diagnosis (NanoMag), and laser-activated nanoparticles for cancer treatment (NanoPDT).

UB received company stock as part of the licensing agreement, and sold the shares in February for $1.35 million. In accordance with university policy, the majority will return to UB, to be reinvested in research.

This is a real success story, says Vice Provost Robert Genco, who oversees the Office of Science, Technology Transfer and Economic Outreach (STOR). The office helps commercialize UB discoveries, in part by handling patent applications and licensing negotiations for technologies developed at the university.

Nanobiotix is an example of how UB is benefiting society: As a postdoctoral researcher here, Laurent saw the medical and commercial potential of the work he was doing and decided that he wanted to take it further, Genco says. Were a global university and were seeding companies not only in Western New York, but around the world.

At UB, Levy conducted postdoctoral research with SUNY Distinguished Professor Paras Prasad, executive director of the Institute of Laser, Photonics and Biophotonics (ILPB) at UB. Prasad is one of the worlds pre-eminent thinkers in nanomedicine, which uses super-small particles, materials and devices to treat and diagnose disease.

In the 1990s, when Levy was in Buffalo, the nanomedicine field was just emerging. He joined Prasads lab, where he developed the idea of using the unique properties of nanoparticles to kill cancer cells.

More:
UB spinoff Nanobiotix working to bring cancer treatment to market

Gender stereotypes keep women in the out-group

Posted on by

PUBLIC RELEASE DATE:

29-May-2014

Contact: Vicki Cohn vcohn@liebertpub.com 914-740-2100 Mary Ann Liebert, Inc./Genetic Engineering News

New Rochelle, NY, May 29, 2014Women have accounted for half the students in U.S. medical schools for nearly two decades, but as professors, deans, and department chairs in medical schools their numbers still lag far behind those of men. Why long-held gender stereotypes are keeping women from achieving career advancement in academic medicine and what can be done to change the institutional culture are explored in an article in Journal of Women's Health, a peer-reviewed publication from Mary Ann Liebert, Inc., publishers. The article is available free on the Journal of Women's Health website.

In "Stuck in the Out-Group: Jennifer Can't Grow Up, Jane's Invisible, and Janet's Over the Hill," Anna Kaatz, PhD, MPH and Molly Carnes, MD, MS, University of Wisconsin-Madison, present examples of three women at different stages of their careers to illustrate the ways in which gender stereotypes can influence people's judgment and negatively affect women in social interactions, causing them to be in the out-group and lose out on opportunities for professional advancement.

"Challenging cultural stereotypes about women and men is a critical step toward achieving gender equity in academic medicine," says Susan G. Kornstein, MD, Editor-in-Chief of Journal of Women's Health, Executive Director of the Virginia Commonwealth University Institute for Women's Health, Richmond, VA, and President of the Academy of Women's Health.

###

About the Journal

Journal of Women's Health, published monthly, is a core multidisciplinary journal dedicated to the diseases and conditions that hold greater risk for or are more prevalent among women, as well as diseases that present differently in women. The Journal covers the latest advances and clinical applications of new diagnostic procedures and therapeutic protocols for the prevention and management of women's healthcare issues. Complete tables of content and a sample issue may be viewed on the Journal of Women's Health website. Journal of Women's Health is the official journal of the Academy of Women's Health and the Society for Women's Health Research.

About the Academy

See the original post here:
Gender stereotypes keep women in the out-group

House Science, Space, and Technology Committee Democrats Oppose FIRST Act

Posted on by

Today, the Committee on Science, Space, and Technology completed the markup of H.R. 4186, Frontiers in Innovation, Research, Science, and Technology Act of 2014 (FIRST). Last week, the Committee began consideration of the FIRST Act. Roll call votes on amendments and on final passage were delayed until today.

Congress passed bipartisan Competes legislation in 2007 and 2010 which laid out bold policy directions for U.S. scientific research and innovation. The FIRST Act attempts to replace parts of the Competes legislation, but the bill has numerous problems that make it unacceptable for Committee Democrats. H.R. 4186 passed the Committee as amended on a party-line recorded vote.

Ms. Johnson said after the markup, "The America Competes Act is one of the crowning achievements of the Science Committee. It sought to ensure our commitment to maintaining our scientific and technological leadership now and long into the future. What we have done today with the FIRST Act not only fails to advance our science and innovation enterprise, it actually damages it. The Democratic Members of this Committee made every effort to improve this misguided and flawed piece of legislation and we were rebuffed at every turn. This is a sad day for this Committee."

X

Read this article:
House Science, Space, and Technology Committee Democrats Oppose FIRST Act

GMOs: Dont be confused

Posted on by

Genetically modified organisms (also called GE for genetic engineering), are plants or animals created through the gene splicing techniques of biotechnology. They take fish genes (DNA), for example, and inject them into the tomatos DNA.

Most modified foods have been grown to resist chemicals, pests or disease. Thats all fine in theory, but a growing body of evidence connects GMOs with health problems, environmental damage, and more.

Of course Monsanto and other biotech companies say GE foods are safe to eat. Promises of increased yields, drought tolerance, enhanced nutrition, or any other consumer benefit have all proved false since they started doing this in the 1990s.

Most developed nations do not consider GMOs to be safe. In more than 50 countries around the world, including Australia, Japan, China, India and all of the European Union countries, there are significant restrictions or outright bans on the production and sale of GMOs. But here in the U.S., our government has approved GMOs based on studies conducted by the same corporations that created them and profit from their sale!

If theres no risk in eating products that contain GMOs then there should be no problem labeling them.

By supporting labeling, companies would say, Theres no risk, we have nothing to hide, says David Ropeik, creator and director of Improving Media Coverage of Risk.

We have the right to know how our food is grown. More people are realizing that the food they eat directly affects their health.

Vote YES for labeling of GMOs! Go to http://www.nongmoproject.org for more info.

TANYA OSTERSON

Coeur dAlene

See the rest here:
GMOs: Dont be confused

Learn quickly why regulations alone are sometimes not enough to prevent all injuries – Video

Posted on by


Learn quickly why regulations alone are sometimes not enough to prevent all injuries
http://www.cbsafety.com See Dr. Boyce in Mining Quarterly: http://issuu.com/elkodaily/docs/mining_quarterly_fall_2013/95?e=5871931/5145752 Hire Speaker: http://www.tinyurl.com/keynoteSVKS , continue scrolling...

By: admincbsafety

Link:
Learn quickly why regulations alone are sometimes not enough to prevent all injuries - Video

Rainy days make us just as happy as sunshine

Posted on by

They expected that people in California would be happier because it is more sunny but they found that levels of happiness were exactly the same.

If it is sunny everyday you get used to it and the sunshine doesnt make you any happier.

Most of the time the weather doesnt affect out wellbeing at all. But when we think about it, and think that it does, thats when we get miserable.

In his new book, Happiness By Design Dolan argues that we can think ourselves happy by diverting our attention away from what makes us sad.

Most of our anxieties come from what might be, he argues, If you want to be happier pay attention to the things that make you feel good.

We also need to manage a reallocation of our time towards both pleasure and purpose.

Prof Dolan, who helped the Office for National Statistics come up with new measures for happiness and wellbeing, also claimed that a problem shared was not always a problem halved.

He argued that it was harmful to make people relive traumatic events through therapy, claiming that humans are actually very good at being able to get over tragedy and loss.

After a traumatic event there is an assumption that people are expecting a lot of support and, yes grief is there and they need help, he said.

But those interventions can be harmful. They actually lock in the emotions of the past.

Visit link:
Rainy days make us just as happy as sunshine