COVID-19 Impact and Recovery Analysis on Cell Freezing Media for Cell Therapy Market 2020-2026 by BioLife Solutions, Akron Biotechnology, GE…

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BioLife SolutionsAkron BiotechnologyGE HealthcareThermo Fisher ScientificBiological IndustriesMerckWAK-Chemie MedicalZenoaq

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The Cell Freezing Media for Cell Therapy market report is segmented into Type by following categories;With FBSWithout FBS

The Cell Freezing Media for Cell Therapy market report is segmented into Application by following categories;Human Embryonic Stem CellsCAR-T Cell TherapyNeural Stem Cell TherapyMesenchymal Stem Cell TherapyHematopoietic Stem Cell TransplantationOther

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COVID-19 Impact and Recovery Analysis on Cell Freezing Media for Cell Therapy Market 2020-2026 by BioLife Solutions, Akron Biotechnology, GE...

13 promising Covid-19 treatments emerging from Israel – The Yucatan Times

In parallel to vaccine research, theres an urgent need for effective treatments for the respiratory disease caused by the SARS-CoV-2 coronavirus.

ISRAEL (Scientists across the globe are working on vaccines to prevent Covid-19 infection. After initial vaccines are approved, there is an urgent need for effective treatments for the respiratory disease caused by the SARS-CoV-2 coronavirus.

Most potential treatments target the life-threatening lung inflammation typical of covid-19 severe cases. Its caused by a phenomenon called a cytokine storm.

Cytokines are proteins that trigger inflammation as a natural response to infection. In response to a virus overload, in this case, in the lungs, the immune system activates a storm of cytokines. Too many cytokines lead to too much inflammation, which can damage the lungs and cause respiratory distress.

Israeli hospitals were among the first anywhere to use dexamethasone, a steroid drug, to stop cytokines storms and reduce lung inflammation in severely ill Covid-19 patients. However, steroids can suppress the immune response too actively.

Additionally, an Israeli hospital is among the first to do a randomized, double-blind, placebo-controlled clinical trial of ivermectin, a drug to treat parasitic infections in people and animals, to see if it can shorten the duration of the disease if given to Covid-19 patients immediately after diagnosis.

Israelis are also formulating novel therapeutics of their own. Here are 13 potential Israeli treatments using a variety of approaches.

PluristemOn June 11, Pluristem Therapeutics of Haifa announced a multicenter Phase 2 US Food and Drug Administration (FDA) efficacy and safety study of its PLX-PAD cells for treating severe Covid-19 complicated by acute respiratory distress syndrome (ARDS).

PLX, an injected regenerative placenta-derived cell therapy, stimulates the immune systems natural regulatory T cells and M2 macrophages, possibly preventing or reversing a cytokine storm. PLX cells potentially reduce the incidence or severity of Covid-19 pneumonia and pneumonitis.

Pluristem has treated Covid-19 patients under compassionate use programs in the United States and Israel. Initial data from 18 patients showed that 75% were off mechanical ventilation within 28 days.

PLX cells are available off-the-shelf and once commercialized, can be manufactured in large-scale quantities, offering a key advantage in addressing a global pandemic, the company said.

SilkimJerusalem-based Silkim Pharma recently submitted Coronzot, its novel treatment for Covid-19 patients with moderate to severe symptoms, to the FDAs Investigational New Drug (IND) program.

IND designation would give Silkim permission to start human clinical trials and ship Coronzot across state lines before a marketing application has been approved.

Coronzots novel mechanism targets a pivotal factor in cytokine storms. It removes an inflammatory overaccumulation of labile iron and replaces it with a minute amount of gallium or zinc.

This not only suppresses the storm but also inhibits viral proteins that attack the lungs and heart. Gallium inhibits virus replication and promotes apoptosis (self-destruction) of already invaded cells. Zinc helps suppress inflammatory reactions and enzymes that enable coronavirus replication.

The company is actively engaged in the FDA process. We look forward to finalizing the IND and then moving towards conducting clinical studies of Coronzot for Covid-19, said Silkim Pharma CEO Dror Chevion.

RedHill BiopharmaRedHill Biopharma, based in Raleigh, North Carolina, and Tel Aviv, is racing to advance our development program with opaganib for Covid-19, according to a June 10 statement by Dr. Mark L. Levitt, RedHill medical director.

RedHill acquired opaganib from US-based Apogee Biotechnology, which developed this oral drug to fight cancer, inflammation, and viruses.

RedHill has seen encouraging preliminary findings from six Israeli Covid-19 patients given opaganib under compassionate use to reduce lung inflammation. All were weaned from supplemental oxygen and discharged from the hospital without having to receive mechanical ventilation.

RedHill plans a multicenter, randomized, double-blind, parallel-arm, placebo-controlled Phase 2/3 clinical study on 270 US patients with severe Covid-19 pneumonia.

We are expanding the development program to Russia and additional European countries, parallel with the US clinical study, to accelerate the collection of robust data on the potential efficacy of opaganib against Covid-19, said Levitt.

The company is working with government agencies worldwide to allow more patients access to the investigational drug through clinical studies and compassionate use programs.

InnoCanInnoCan founders, from left, Ron Mayron, Iris Bincovich, Yoram Drucker. Photo by Rotem LahavInnoCan Pharma Israel and Tel Aviv University tech-transfer company Ramot are collaborating to develop a new CBD-loaded exosome technology to fight lung inflammation.

Exosomes, small particles created from stem cells, can act as homing missiles targeting specific damaged organs and facilitating cell-to-cell communication.

Combining the cell-healing properties of exosomes with the anti-inflammatory properties of the cannabis-derived compound CBD is expected to have a strong synergetic effect. The treatment is administrated by inhalation.

Stero BiotechsStero Biotechs of Bnei Brak has started a small clinical trial at Rabin Medical Center in Petah Tikva on the tolerability, safety, and efficacy of CBD-enhanced steroid treatment for hospitalized Covid-19 patients.

Steroid treatment is usually the first or second line of treatment for hospitalized patients. CBD enhances the therapeutic effect of steroid treatment and treats the bio-mechanism affected by the virus, the company explained.

Eybna and CannaSoulTwo Israeli cannabis R & D firms, Eybna Technologies and CannaSoul Analytics, develop a proprietary terpene formulation for modulating cytokine storms.

Terpenes are organic compounds found in cannabis and other plants. Studies suggest they can be effective antiviral agents.

CannaSouls Cytokine Storm Assay (from its Myplant-Bio subsidiary) will aid in optimizing and customizing Eybnas novel NT-VRL inhaled formulation for treatment and prevention of viral infections in high-risk populations and actively ill patients.

The FDA considers this assay as a good predictor for cytokine storm response and immunotoxicity, and it is commonly required in the development of biological treatments, according to CannaSoul Chairman and CSO Prof. Dedi Meiri.

The NT-VRL formulation intended to be used via inhalation, said Eybna CEO Nadav Eyal. This delivery method dramatically increases the terpenes bioavailability by directly contacting the infected cells in the respiratory system.

CannaSoul aims to identify other cannabis molecules capable of suppressing a cytokine storm in response to Covid-19 without completely suppressing the immune system. It is also studying how cannabis molecules could modulate the ACE2 receptor, which allows the virus to inject its genetic expression into human cells.

KamadaBased in Rehovot, Kamada has begun supplying its experimental plasma-derived Hyperimmune IgG therapy for compassionate use in severe Covid-19 cases in Israel.

The treatment is based on plasma donated by recovered Israeli Covid-19 patients. One critically ill patient at Hadassah Medical Center showed initial improvement after having the experimental IgG therapy but ultimately did not survive.

During the third quarter of this year, Kamada expects to start a Phase 1/2 clinical study in hospitalized Covid-19 patients in Israel and hold a pre-IND meeting with the FDA to expand clinical development in the United States in partnership with Kedrion Biopharma.

Kedrion is collecting plasma from recovered American Covid-19 patients at 23 FDA-approved centers across the United States. This will be used by Kamada to manufacture additional batches of the product.

To the best of our knowledge, Kamada is the first company globally to complete manufacturing of a plasma-derived IgG product for the treatment of Covid-19, said Kamada CEO Amir London.

Israel Institute for Biological ResearchThe government-run Israel Institute for Biological Research (IIBR) announced in May that analogs of two drugs for Gauchers disease proved effective against SARS-CoV-2.

This drug cocktail is made up of the FDA-approved Cerdelga and an analog of the second drug in advanced stages of the approval process.

The IIBR study on cell cultures demonstrated that the two-drug treatment significantly reduced the coronaviruss replication capacity and the destruction of the infected cell. This potential treatment is currently being tested in animals infected with the coronavirus.

The IIRB also isolated several critical coronavirus antibodies that successfully neutralized aggressive coronavirus in lab tests. These could form the basis of future treatment following further testing.

PepticomBased in Jerusalem, Pepticom computationally designs novel peptide drug candidates using artificial intelligence. The company raised $5 million last year.

Three months ago, Pepticom began implementing its proprietary AI technology on various coronavirus proteins to identify novel peptides that inhibit the interaction between the spike protein of SARS-Cov-2 and the ACE2 receptor thereby stopping the virus from entering the cell.

CEO Immanuel Lerner says three such proteins have already been identified and are being validated in the lab.

Using AI is a fast way to find these peptides, which are less expensive and easier to produce than antibodies, Lerner tells ISRAEL21c. Many parties are interested in looking at our results and finding ways to develop this further.

Bonus BioGroupIn April, Bonus BioGroup initiated a preclinical study of MesenCure, its unique drug for treating acute and life-threatening respiratory distress in coronavirus and pneumonia patients.

MesenCure consists of activated mesenchymal stromal (stem) cells from healthy adult donors. The activation of these MSCs is intended to boost their ability to reduce lung inflammation, promote regeneration of the diseased lung tissue, and alleviate respiratory and other symptoms in the lungs.

The development of MesenCure relies on more than a decade of related experience and technologies that Bonus BioGroup has used in developing its lead product, a tissue-engineered bone graft, also based on MSCs.

With the current coronavirus outbreak, Bonus BioGroup has started tissue culture studies into the potential of these MSCs, further activated, to alleviate inflammation, including in the lungs, and possibly attenuate the cytokine storm in COVID-19 patients, the company explained.

The preclinical study in several animal models is expected to be completed in the third quarter of 2020. The company said preliminary results indicate that following the treatment with MesenCure, the microscopic appearance of the treated lungs was similar to a healthy lung, and a significant improvement in additional related parameters was achieved.

Bonus BioGroup presented these results to 1,800 scientists, physicians, and public opinion leaders at the International Society for Cell & Gene Therapy virtual conference in May.

NanoGhostTechnion-Israel Institute of Technology Prof. Marcelle Machluf developed a drug-delivery technology that uses reconstructed mesenchymal stem cells as nano-vesicles to transport medicine directly to a target.

NanoGhost is the startup she established to commercialize the technology, which has proven successful in treating pancreatic, lung, breast, prostate, and brain cancer in mice. The NanoGhost technology has been patented in the United States and Europe, with additional patents pending in India and China.

Now, Machluf is adapting her technology to create decoy NanoGhosts that attract and entrap the coronavirus, making for a less severe infection. She explains it in the video below.

EnlivexEnlivex Therapeutics of Ness Ziona is developing Allocetra, a novel immunotherapy medication to treat organ dysfunction and acute multiple organ failure associated with sepsis and Covid-19, as well as solid tumors.

Allocetra rebalances a severely unbalanced immune system by engaging with the immune systems own regulation mechanisms. It is designed to restore a safe immune balance following a cytokine storm.

Enlivex is starting to recruit Covid-19 patients in Israel and in the United States to test the potential effect of Allocetra on moderate to severe cases. A patent from the Japan Patent Office is expected during the third quarter of 2020.

Weizmann Institute of ScienceOrganic chemist Nir London of the Weizmann Institute of Science in Rehovot is co-leading a collaborative project to identify small molecules that can bind to and inhibit a protease enzyme that the SARS-CoV-2 virus needs to reproduce.

London and his research team had previously developed an advanced method for identifying potential inhibitors for numerous proteins.

So far, we have made close to 800 compounds and tested more than 650 and keep getting closer to sufficiently potent inhibitors, London tells ISRAEL21c.

These inhibitors will be further investigated for their potential as a starting point for new drugs against the coronavirus.

London is working with researchers from Oxford University, Memorial Sloan Kettering Cancer Center, University of British Columbia, and Californian-based biotech company.

The Yucatan TimesNewsroom

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13 promising Covid-19 treatments emerging from Israel - The Yucatan Times

Stem cell therapies receive MRFF funding – Mirage News

Associate Professor Rebecca Lim has been awarded more than $470,000 from the Australian Governments Medical Research Future Fund to pursue research into stem cell therapies for liver disease.

A/Prof Lim leads the Regenerative Medicine and Cellular Therapies group at Hudson Institute. Together with Monash University, Obstetrics and Gynaecology (Material Science and Engineering) and Baker Heart and Diabetes Institute, she was awarded the $472,680 Department of Health funding to work on gastroenterology, regenerative medicine and cellular biology (including stem cells and tissue engineering).

The Stem Cell Therapies Mission is funded via the MRFF and will invest $150 million over nine years to develop innovative, safe and effective treatments accessible to all Australians who need them.

Congratulations also to our collaborators, the Australian and New Zealand Childrens Haematology Oncology Group (ANZCHOG), who were awarded three MRFF grants, totalling $1,965,011 for their studies on childhood brain cancer. The three trials were funded through the MRFF Clinical Trials Activity (Rare Cancers, Rare Diseases and Unmet Need) Childhood Brain Cancer Opportunity, which will enable ANZCHOG to continue to provide Australian children diagnosed with brain cancer access to innovative clinical trials.

CONNECT-1903 is an international study that will assess if treatment with lactrotrectinib is safe and can control the growth of tumours in children with high grade gliomas. The second international study is the MET-MED trial, examining if metformin can improve cognitive recovery in paediatric medulloblastoma patients. The final successful application, the TiNT Trial, is a phase II trial using trametinib (a promising MEK inhibitor) in patients with neurofibromatosis type 1 associated progressive optic pathway gliomas. This trial was designed and developed by Australian and New Zealand researchers, essential for capacity building and leading innovative trial research in the paediatric oncology space.

Liver disease is responsible for one quarter of all organ transplants in Australia and represents a significant healthcare burden. The most common liver disease is non-alcoholic fatty liver disease (NAFLD), which itself is benign but in association with chronic inflammation (non-alcoholic steatohepatitis; NASH), can progress to cirrhosis and liver cancer.

By 2020, NASH will have replaced hepatitis C as the number one reason for liver transplantation. There is no cure for NAFLD/NASH. Alternatives are urgently needed for patients with end stage NAFLD/NASH who are not candidates for liver transplantation or for whom no donor is available.

The research team aim to develop a multivalent therapeutic for this complex disease based on extracellular vesicles (EV) released by amniotic epithelial cells (hAEC) that addresses fibrosis, apoptosis, oxidative stress and endogenous repair.

Preliminary research has shown that EVs released by hAECs are anti-fibrotic and support the differentiation of liver progenitor cells, promoting recovery of liver function in chronic liver disease.

The teams pilot data indicates that hAECs cultured on softer 3D microcarriers can significantly increase EV yield as well as biological potency compared to culture on traditional 2D tissue culture plastic.

They hypothesise that it is possible to tune the potency of hAEC-EVs by manipulating mechanotransduction through culture on softer microcarriers which are specifically functionalised to improve anti-fibrotic effects for NAFLD/NASH.

The aim is to

(i) Develop a novel method of hAEC-EV manufacturing for optimal EV yield and potency through the manipulation of microcarrier stiffness and functionalisation and;

(ii) Evaluate an oral formulation of hAEC-EVs against competitor treatments in preclinical mouse model of NASH.

The team brings combined expertise of hAEC and EV biology, materials science, NAFLD/NASH management and clinical translation to address this urgent unmet medical need.

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Stem cell therapies receive MRFF funding - Mirage News

Outlook on the Worldwide Regenerative Medicine Industry to 2024 – Rising Global Healthcare Expenditure Presents Opportunities – GlobeNewswire

Dublin, June 22, 2020 (GLOBE NEWSWIRE) -- The "Global Regenerative Medicine Market: Size & Forecast with Impact Analysis of COVID-19 (2020-2024)" report has been added to ResearchAndMarkets.com's offering.

This report provides an in-depth analysis of the global regenerative medicine market with description of market sizing and growth. The analysis includes market by value, by product, by material and by region. Furthermore, the report also provides detailed product analysis, material analysis and regional analysis.

Moreover, the report also assesses the key opportunities in the market and outlines the factors that are and would be driving the growth of the industry. Growth of the overall global regenerative medicine market has also been forecasted for the years 2020-2024, taking into consideration the previous growth patterns, the growth drivers and the current and future trends.

Region Coverage:

Company Coverage:

Regenerative medicines emphasise on the regeneration or replacement of tissues, cells or organs of the human body to cure the problem caused by disease or injury. The treatment fortifies the human cells to heal up or transplant stem cells into the body to regenerate lost tissues or organs or to recover impaired functionality. There are three types of stem cells that can be used in regenerative medicine: somatic stem cells, embryonic stem cells (ES cells) and induced pluripotent stem cells (iPS cells).

The regenerative medicine also has the capability to treat chronic diseases and conditions, including Alzheimer's, diabetes, Parkinson's, heart disease, osteoporosis, renal failure, spinal cord injuries, etc. Regenerative medicines can be bifurcated into different product type i.e., cell therapy, tissue engineering, gene therapy and small molecules and biologics. In addition, on the basis of material regenerative medicine can be segmented into biologically derived material, synthetic material, genetically engineered materials and pharmaceuticals.

The global regenerative medicine market has surged at a progressive rate over the years and the market is further anticipated to augment during the forecasted years 2020 to 2024. The market would propel owing to numerous growth drivers like growth in geriatric population, rising global healthcare expenditure, increasing diabetic population, escalating number of cancer patients, rising prevalence of cardiovascular disease and surging obese population.

Though, the market faces some challenges which are hindering the growth of the market. Some of the major challenges faced by the industry are: legal obligation and high cost of treatment. Whereas, the market growth would be further supported by various market trends like three dimensional bioprinting , artificial intelligence to advance regenerative medicine, etc.

Key Topics Covered:

1. Executive Summary

2. Introduction2.1 Regenerative Medicine: An Overview2.2 Regeneration in Humans: An Overview2.3 Expansion in Peripheral Industries of Regenerative Medicine2.4 Approval System for Regenerative Medicine Products2.5 Regenerative Medicine Segmentation

3. Global Market Analysis3.1 Global Regenerative Medicine Market: An Analysis3.1.1 Global Regenerative Medicine Market by Value3.1.2 Global Regenerative Medicine Market by Products (Cell Therapy, Tissue Engineering, Gene Therapy and Small Molecules and Biologics)3.1.3 Global Regenerative Medicine Market by Material (Biologically Derived Material, Synthetic Material, Genetically Engineered Materials and Pharmaceuticals)3.1.4 Global Regenerative Medicine Market by Region (North America, Europe, Asia Pacific and ROW)

3.2 Global Regenerative Medicine Market: Product Analysis3.2.1 Global Cell Therapy Regenerative Medicine Market by Value3.2.2 Global Tissue Engineering Regenerative Medicine Market by Value3.2.3 Global Gene Therapy Regenerative Medicine Market by Value3.2.4 Global Small Molecules and Biologics Regenerative Medicine Market by Value

3.3 Global Regenerative Medicine Market: Material Analysis3.3.1 Global Biologically Derived Material Market by Value3.3.2 Global Synthetic Material Market by Value3.3.3 Global Genetically Engineered Materials Market by Value3.3.4 Global Regenerative Medicine Pharmaceuticals Market by Value

4. Regional Market Analysis4.1 North America Regenerative Medicine Market: An Analysis4.2 Europe Regenerative Medicine Market: An Analysis4.3 Asia Pacific Regenerative Medicine Market: An Analysis4.4 ROW Regenerative Medicine Market: An Analysis

5. COVID-195.1 Impact of Covid-195.2 Response of Industry to Covid-195.3 Variation in Organic Traffic5.4 Regional Impact of COVID-19

6. Market Dynamics6.1 Growth Drivers6.1.1 Growth in Geriatric Population6.1.2 Rising Global Healthcare Expenditure6.1.3 Increasing Diabetic Population6.1.4 Escalating Number of Cancer Patients6.1.5 Rising Prevalence of Cardiovascular Disease6.1.6 Surging Obese Population6.2 Challenges6.2.1 Legal Obligation6.2.2 High Cost of Treatment6.3 Market Trends6.3.1 3D Bio-Printing6.3.2 Artificial Intelligence to Advance Regenerative Medicine

7. Competitive Landscape7.1 Global Regenerative Medicine Market Players: A Financial Comparison7.2 Global Regenerative Medicine Market Players' by Research & Development Expenditure

8. Company Profiles8.1 Bristol Myers Squibb (Celgene Corporation)8.1.1 Business Overview8.1.2 Financial Overview8.1.3 Business Strategy8.2 Medtronic Plc8.2.1 Business Overview8.2.2 Financial Overview8.2.3 Business Strategy8.3 Smith+Nephew (Osiris Therapeutics, Inc.)8.3.1 Business Overview8.3.2 Financial Overview8.3.3 Business Strategy8.4 Novartis AG8.4.1 Business Overview8.4.2 Financial Overview8.4.3 Business Strategy

For more information about this report visit https://www.researchandmarkets.com/r/w15smu

Research and Markets also offers Custom Research services providing focused, comprehensive and tailored research.

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Outlook on the Worldwide Regenerative Medicine Industry to 2024 - Rising Global Healthcare Expenditure Presents Opportunities - GlobeNewswire

Preventing misleading claim of COVID-19 cure – The Jakarta Post – Jakarta Post

Researchers atAirlangga University (Unair) and the State Intelligence Agency (BIN) released on June 12what appeared to be an encouraging statement:the discovery of five combination drug therapies and two stem cell therapies for treating COVID-19.

The acute respiratory disease caused by the SARS-CoV-2 virus has claimed at least 2,000 lives in Indonesia to date.

The joint statementattributed to Unair andBIN also said that themedicines were ready for distributionin treating COVID-19 patients.

Drug combinations

The five combination therapiesfor COVID-19 are: lopinavir/ritonavir with azithromycin, lopinavir/ritonavir with doxycycline, lopinavir/ritonavir with clarithromycin, hydroxychloroquine with azithromycin, and hydroxychloroquine with doxycycline.

In addition, the statementclaimed that the researchers had identified two types of isolated stemcells that inhibitedSARS-CoV-2 activity:hematopoietic stem cells (HSCs) and natural killer (NK) cells.

Their goodwill to bring an end tothe pandemic should be appreciated. Unfortunately, their conclusions seem premature and could lead to more damaging consequences for the public.

In theory, the drug combinationsrecommended by Unair and BIN have the potentialto inhibit SARS-CoV-2. Lopinavir and ritonavir are protease inhibitors that are currently used to treat people with HIV/AIDS. Hydroxychloroquine is a malarial treatment, while azithromycin, doxycyclineand clarithromycin are antibiotics that can fight secondary bacterial (not viral) infections in COVID-19 patients who have developed pneumonia.

However, theory does not necessarily work inpractice. Noneof these drugs have been provenin any clinical study to bea safe and effective treatmentfor COVID-19. The World Health Organization (WHO) has started clinical trials involving thousands of patients in dozens of countries to test the efficacy and safety of these drugs. So far, there has been no clear indication that these drugs, whether individually or in combination,are effective in treating COVID-19.

In fact, evidence exists that hydroxychloroquine may worsen the condition of patients, which led the WHO to suspend the clinical trial of the drug.

Unair and BIN are correct in conducting in vitro (test tube) experiments to verify the effect and toxicity of the drugs for SARS-CoV-2. Unfortunately, they have not communicated in any clear way on how they designed, executedand analyzed their experiments.

We do not know how they cultured the virus, what kind of negative controls they used, what kind of cells they testedor whether the cells they usedcontained the necessary receptors for SARS-CoV-2 to enter a human cell. More importantly, it is crucial to note thatthe results of in vitro experiments(however encouraging) cannot be assumed to be safe and effectivetreatments for direct use in human patients. For example, the United States Food and Drug Administration (FDA) on averageapprovedless than 10 percent of drugs that performed well in vitroas safe for humanprescription.

The human lungs contain millions of cells comprising dozens of different types that perform intricate interactions. The proposed drugs can also affect other organs in the human body and cause adverse reactions.

Instead of announcing that these five combination therapiesare ready for treating COVID-19, Unair and BIN should first run arandomizedcontrolled trial (RCT) to confirm their findings.Recruiting diverse patient populations is also critical to ensuring thefairness and robustness of the study.

Despite their good intentions, all the drugs that Unair and BIN researchers have proposedare strong medicines, whether individually or in combination, that can potentially cause unwanted sideeffects and even death. Surely none of us want to rush into an unproven treatmentin order to avoid developing even more overwhelming health problems in the future.

Stem cell therapy

Stem cell therapy is another COVID-19treatment that Unair and BIN researchers have proposed. Stem cells are undifferentiated cells thathas the potential to develop into many different types of cells in human body. One type of stem cell they have proposed is hematopoietic stem cells (HSCs), whichdevelop into blood cells, includingimmune cells that help the body fight pathogens and infections.

However, stem cell therapy is still considered very risky, expensiveand limited to treating a few cancers, such as leukemia. No evidence exists that stem cell therapy is efficient in treating viral infections in the human bodysuch asCOVID-19.

As with the drug therapies, the Unair and BIN researchers did not say how they performed their stem cell experiment. We have no information oncrucial aspects likestem cell culturing protocol, the stem cell's differentiation status, tumorigenic potential, proliferation capacity orexcretion patterns, and how they tested stem cell activity against SARS-CoV-2.

Even if the researchersestablished a sound experimentalprotocol for their in vitro experiments, administering stem cell therapy to COVID-19 patients is an extremely dangerous procedure that can result in undesirable costs, such as malignancy, the stem cells attacking other healthy cellsand possibly death.

Injecting stem cells into the human body carries a huge risk of immuno-rejection (think of a blood type A patient receivinga bloodtype B infusion, but witha much more severe reaction). The doctors administering the treatment must isolate autologousstem cells from the individual patient or allogenic stem cells froma separate donor, culture them, and reinject the treated cells into the patient. These processes are extremely laborious, time-consumingand expensive, and there is no clear indication that the treatment will produce a safe and successful outcome against viral infection.

This is hardly a sound strategy to use during a pandemic. Furthermore, thecommon procedureis to administer powerful immunosuppressants to reduce the strength of thepatients immune system, particularly in the allogenic scenario, which would minimizethe risk of immuno-rejection. However, it would be unwise to shut down a COVID-19patient's immune system that is neededto work properly for their body to fight SARS-CoV-2.

Unair and BIN's valiant effortsshould still be applauded, as they are committed to treating COVID-19 and ending the pandemic. The public is waiting impatiently for the health crisis to subside so they canresume their normal lives.

However, everyone should realize that discovering treatments and developing a potential vaccine for a disease that was virtually unknown six months ago takes a lot of time and resources.

Unair and BIN said that they had submitted their research to at least seven peer-reviewed internationaljournals, but this does not mean that their research is validated immediately. It still needs reviewing and questioned by their scientific peers.

It is necessary for the researchers to publish their findings onan open access, preprint repository for biological or medical research papers like BiorXiv or MedrXiv, so that scientists and people around the worldcan scrutinize and engage in healthy scientific discourse.

We absolutely deserve good news during the pandemicon safe medical treatmentsand vaccines. We also deserve complete, clear and transparent public communications from all COVID-19 stakeholders, including researchers and governments, to ensure that all actions are evidence-based, safeand effective.

The writer is a research scientist with a PhD in biochemistryfrom the University of Cambridge, which he earned as a recipient of the 2015-2019 Gates Cambridge Scholarship program.

Disclaimer: The opinions expressed in this article are those of the author and do not reflect the official stance of The Jakarta Post.

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Preventing misleading claim of COVID-19 cure - The Jakarta Post - Jakarta Post

Global Stem Cell Therapy for Osteoarthritis Market 2020: Expected Development, Share, Demand And Study Of Key Players- Research Predictions 2025 -…

Global Stem Cell Therapy for Osteoarthritis Market 2020 by Company, Regions, Type and Application, Forecast to 2025 aims to project the value and volume of the market and strategically profile the key players, analyze their growth strategies. The report delivers in-depth data and study of the industry dynamics of this market. The report offers an overview of global Stem Cell Therapy for Osteoarthritis market division like type, application, and region. The market report dynamics trends are made up of opportunities and challenges. The report provides a structure of the market and predicts industry share to rise within the forecast period 2025. The research thoroughly estimates the consumption volume industry by application, manufacturing technology and regions. Further, conclusion, discoveries, and future improvement openings are explored in the report.

The market report opens with an overview of the global Stem Cell Therapy for Osteoarthritis industry, which contains definitions and specifications about the industry. In the next chapter, the report explains the manufacturing cost structure, which includes a thorough analysis of the raw material suppliers and price analysis, equipment suppliers and price analysis, and analysis of labour costs and other costs. The manufacturers have been incorporated in terms of their manufacturing base, basic information, and competitors.

NOTE: This report takes into account the current and future impacts of COVID-19 on this industry and offers you an in-dept analysis of Stem Cell Therapy for Osteoarthritis market.

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Our best analysts have surveyed the market report with the reference of inventories and data given by the key players: Mesoblast, Anterogen, Regeneus, U.S. Stem Cell, Asterias Biotherapeutics

On the basis on the applications, this report focuses on the status and outlook for major applications/end users, sales volume, and growth rate for each application, including: Osteoarthritis (unspecified), Knee Osteoarthritis, Shoulder Osteoarthritis, Hip Osteoarthritis,

On the basis of types/products, this report displays the revenue (Million USD), product price, market share, and growth rate of each type, split into: Monotherapy, Combination Therapy,

Key Issues Addressed by Market:

It is very significant to have global Stem Cell Therapy for Osteoarthritis segmentation analysis to figure out the essential factors of growth and development of the market. The report provides well summarized and reliable information about every segment of growth, development, production, demand, types, application of the specific product which will assist players to focus and highlight on.

Moreover, each geographic segment of the global Stem Cell Therapy for Osteoarthritis market has been independently surveyed along with pricing, distribution and demand data for geographic market notably: North America (United States, Canada and Mexico), Europe (Germany, France, UK, Russia and Italy), Asia-Pacific (China, Japan, Korea, India and Southeast Asia), South America (Brazil, Argentina, etc.), Middle East& Africa (Saudi Arabia, Egypt, Nigeria and South Africa)

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Global Stem Cell Therapy for Osteoarthritis Market 2020: Expected Development, Share, Demand And Study Of Key Players- Research Predictions 2025 -...

Stem Cell Therapy Market 2020 Key Players, Share, Trend, Segmentation and Forecast to 2026 – Cole of Duty

New Jersey, United States,- The report is a must-have for business strategists, participants, consultants, researchers, investors, entrepreneurs, and other interested parties associated with the Stem Cell Therapy Market. It is also a highly useful resource for those looking to foray into the Stem Cell Therapy market. Besides Porters Five Forces and SWOT analysis, it offers detailed value chain assessment, comprehensive study on market dynamics including drivers, restraints, and opportunities, recent trends, and industry performance analysis. Furthermore, it digs deep into critical aspects of key subjects such as market competition, regional growth, and market segmentation so that readers could gain sound understanding of the Stem Cell Therapy market.

The research study is a brilliant account of macroeconomic and microeconomic factors influencing the growth of the Stem Cell Therapy market. This will help market players to make appropriate changes in their approach toward attaining growth and sustaining their position in the industry. The Stem Cell Therapy market is segmented as per type of product, application, and geography. Each segment is evaluated in great detail so that players can focus on high-growth areas of the Stem Cell Therapy market and increase their sales growth. Even the competitive landscape is shed light upon for players to build powerful strategies and give a tough competition to other participants in the Stem Cell Therapy market.

The competitive analysis included in the report helps readers to become aware of unique characteristics of the vendor landscape and crucial factors impacting the market competition. It is a very important tool that players need to have in their arsenal for cementing a position of strength in the Stem Cell Therapy market. Using this report, players can use effective business tactics to attract customers and improve their growth in the Stem Cell Therapy market. The study provides significant details about the competitive landscape and allows players to prepare for future challenges beforehand.

Stem Cell Therapy Market Segmentation

This market has been divided into types, applications and regions. The growth of each segment provides a precise calculation and forecast of sales by type and application, in terms of volume and value for the period between 2020 and 2026. This analysis can help you develop your business by targeting qualified niche markets. . Market share data are available at global and regional levels. The regions covered by the report are North America, Europe, Asia-Pacific, the Middle East and Africa and Latin America. Research analysts understand competitive forces and provide competitive analysis for each competitor separately.

Stem Cell Therapy Market by Type:

YYYY

Stem Cell Therapy Market by Application:

ZZZZ

Stem Cell Therapy Market by Region:

North America (The USA, Canada, and Mexico)Europe (Germany, France, the UK, and Rest of Europe)Asia Pacific (China, Japan, India, and Rest of Asia Pacific)Latin America (Brazil and Rest of Latin America.)Middle East &Africa (Saudi Arabia, the UAE, South Africa, and Rest of Middle East & Africa)

The report answers important questions that companies may have when operating in the Stem Cell Therapy market. Some of the questions are given below:

What will be the size of the Stem Cell Therapy market in 2026?

What is the current CAGR of the Stem Cell Therapy market?

What products have the highest growth rates?

Which application is projected to gain a lions share of the Stem Cell Therapy market?

Which region is foretold to create the most number of opportunities in the Stem Cell Therapy market?

Which are the top players currently operating in the Stem Cell Therapy market?

How will the market situation change over the next few years?

What are the common business tactics adopted by players?

What is the growth outlook of the Stem Cell Therapy market?

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Upgrade your market research resources with this comprehensive and accurate report on the Stem Cell Therapy market

Get complete understanding of general market scenarios and future market situations to prepare for rising above the challenges and ensuring strong growth

The report offers in-depth research and various tendencies of the Stem Cell Therapy market

It provides detailed analysis of changing market trends, current and future technologies used, and various strategies adopted by leading players of the Stem Cell Therapy market

It offers recommendations and advice for new entrants of the Stem Cell Therapy market and carefully guides established players for further market growth

Apart from hottest technological advances in the Stem Cell Therapy market, it brings to light the future plans of dominant players in the industry

Table of Contents

Market Overview: This section comes under executive summary and is divided into four sub-sections. It basically introduces the Stem Cell Therapy market while focusing on market size by revenue and production, market segments by type, application, and region, and product scope.

Competition by Manufacturers: It includes five sub-sections, viz. market competitive situation and trends, manufacturers products, areas served, and production sites, average price by manufacturers, revenue share by manufacturers, and production share by manufacturers.

Market Share by Region: It provides regional market shares by production and revenue besides giving details about gross margin, price, and other factors related to the growth of regional markets studied in the report. The review period considered here is 2015-2019.

Company Profiles: Each player is assessed for its market growth in terms of different factors such as markets served, gross margin, price, revenue, production, product specification, and areas served.

Manufacturing Cost Analysis: It is sub-divided into four chapters, viz. industrial chain analysis, manufacturing process analysis, manufacturing cost structure, and key raw materials analysis.

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Stem Cell Therapy Market 2020 Key Players, Share, Trend, Segmentation and Forecast to 2026 - Cole of Duty

Cell Therapy Industry Production, Sales and Consumption Status and Prospects Professional Market Research Report 2020-2025 – 3rd Watch News

The Cell Therapy Market report covers extensive study about the market players operating in the global market. The report offers a complete analysis of the strategies implemented by leading service providers. Additionally, the report contains qualitative and quantitative market evaluation depending on the market segmentation. This report offers an in-depth analysis of the market trends that are influencing the market growth. The report comprises the comprehensive study of geographical regions which may include North America, Europe, Asia Pacific, and the MEA. The report on the Cell Therapy Market is specially designed to provide cutting-edge market intelligence as well as aid investors to take investment estimate decisions.

Leading Companies Reviewed in the Report are:

JCR Pharmaceuticals Co., Ltd., Kolon TissueGene, Inc.; and Medipost and many more.

Get Exclusive Sample of Report on Cell Therapy market is available @ https://www.adroitmarketresearch.com/contacts/request-sample/611

Furthermore, the report covers the PESTLE as well as Porters Five Forces analysis for in-depth comparisons and other significant factors for market analysis. In addition to this, every section of the Cell Therapy research report has offered significant information to provide for service providers to increase their revenue margin, marketing strategy and sales, as well as profit margin. In addition, the Cell Therapy research report offered a comprehensive qualitative as well as quantitative analysis with the several opportunities assessment across the world. Besides, the research report used as a tool for getting extensive market analysis, service providers can recognize the required changes into their operation and gain their position across the global market. In addition, the number of business tactics aids the Cell Therapy Market players to give competition to the other players in the market while recognizing the significant growth prospects.

Likewise, the Cell Therapy research report provides market insights from the huge number of statistics which are collected from robust Cell Therapy Market data such as channel partners, manufacturers, regulatory bodies, as well as decision makers. Similarly, the research report evaluates the market growth rate as well the current market value according to the market dynamics as well as the growth prospects. The market analysis offered in this report is assessed on the basis of market data, market trends, and the number of growth potentials. In addition, it includes an extensive investigation of the market scenario with the in-depth analysis of their major service providers. In addition to this, on the basis of several clients conditions, the Cell Therapy report produces highly customized data that will help regional as well as global service providers to increase their market position over the globe.

Quick Read Table of Contents of this Report @ https://www.adroitmarketresearch.com/industry-reports/cell-therapy-market

Global Cell Therapy market is segmented based by type, application and region.

Based on Type, the market has been segmented into:

By Use & Type Outlook, (Clinical-use,By Cell Therapy Type,,Non-stem Cell Therapies,Stem Cell Therapies,BM, Blood, & Umbilical Cord-derived Stem Cells,Adipose derived cells,Others), By Therapeutic Area, (Malignancies,Muscoskeletal Disorders,Autoimmune Disorders,Dermatology,Others,Research-use), By Therapy Type, (Allogenic Therapies,Autologous Therapies)

The report offers a complete data analysis about the current trends which have developed and are expected to become one of the strongest Cell Therapy Market forces into coming future. Moreover, the research report offers a holistic overview of the Cell Therapy Market, several factors driving the market growth, as well as the companies involved in the Cell Therapy Market. In addition to this, the Cell Therapy report provides the extensive analysis of the market restraints that are responsible for hampering the Cell Therapy Market growth along with the report offers a comprehensive description of each and every aspects and its influence on the market. Furthermore, the Cell Therapy report provides a detailed value chain analysis of the Cell Therapy Market across the world.

Finally, the researchers throw light on different ways to discover the strengths, weaknesses, opportunities, and threats affecting the growth of the Global Cell Therapy Market. The feasibility of the new report is measured in this research report.

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Cell Therapy Industry Production, Sales and Consumption Status and Prospects Professional Market Research Report 2020-2025 - 3rd Watch News

Orca Bio Surfaces With $192M and Recipes for Custom Cell Therapies – Xconomy

XconomySan Francisco

The cancer cell therapies available today are made by tweaking a patients own immune cells to better recognize and fight the disease. Orca Bio is developing what it says is the next generation of cell therapy: custom preparations made without modifying cells or genes.

Orca is already testing its technology in humans, though it has kept that research mostly under wraps. As the startup prepares to reveal its preliminary findings and ramp up its manufacturing capability, the Menlo Park, CA-based biotechannounced on Wednesday the close of $192 million in financing.

The immune system is comprised of many cells that work in concert, says CEO Ivan Dimov. Some cells stimulate activity while other cells block it. But the effects of these immune cells can be dampened by the other cells around them. Orcas therapies are allogeneictheyre made by taking stem and immune cells from healthy donors rather than from the patients themselves, as is the case with autologous treatments. But rather than just taking those healthy cells and putting them into a patient, Orca chooses certain cells from the donor sample and combines them in specific ways. Dimov says each mixture, created from certain cell types that it has assembled in the proper ratio, forms a custom immune army that seeks out cancer cells and leaves healthy tissue alone.

Weve created a novel class of precision therapiesprecise, optimal therapeutic mixtures, he says.

Orcas first disease targets are aggressive blood cancers that require bone marrow transplants as a treatment of last resort. These procedures offer patients a potential cure, but they also come with risks, such as rejection by the immune system.

In recent years, cell therapy has emerged as a new option for aggressive blood cancers that havent responded to treatment. Chimeric antigen receptor T cell therapies, or CAR-Ts, are made by engineering a patients own T cells, multiplying them in a lab, and then infusing them back into the patient to target and fight the cancer. The first CAR-Ts that reached the market were developed by Novartis (NYSE: NVS) and Gilead Sciences (NASDAQ: GILD). These therapies pose the risk of a potentially fatal immune system reaction.

There are other biotechs that are trying to advance CAR-T therapy by making it safer and more scalable. Some of them, like Orca, are developing allogeneic cell therapies. Two such companies, Allogene Therapeutics (NASDAQ: ALLO) and Precision Biosciences (NASDAQ: DTIL), use gene editing to eliminate parts of an immune cell that could prompt an adverse response. Those companies are testing their respective therapies in clinical trials.

Dimov says Orcas custom therapies are meant to allow patients to avoid the complications associated with bone marrow transplants and CAR-T drugs. The descriptor custom needs a bit of clarification: An Orca therapy is not tailored to each patient, but rather customized to generate a particular therapeutic effect, Dimov says. If it works, the right mix not only provides the optimal treatment, it also avoids any adverse immune response. This approach offers a new way to reset and rebuild the immune system, Dimov says.

Orca has two programs in clinical trials. TRGFT-201 is a formulation of T cells and regulatory T cells (a type of cell that tamps down an immune response) that is in Phase 1/2 testing in patients with certain blood cancers. A second program, OGFT-0001, is a formulation of T cells that is in Phase 1, also in blood cancers. The new cash is expected to be enough for Orca to complete Phase 1 tests of the lead program, as well as build the startups manufacturing capacity.

Preliminary data from the studies have not yet been reported but Dimov says a terminally ill cancer patient who received one of the Orca therapies got well enough to leave the hospital. Anecdote aside, while full data are expected in 2022, some early findings are being prepared for peer review.

Orca traces its origins to the laboratory of Irv Weissman, director of the Stanford Institute for Stem Cell Biology and Regenerative Medicine. Dimov joined Weissmans group in 2010 as the field of cell therapy was heating up. At that time, a central obstacle to its progress was figuring out how to make cell therapy manufacturing scalable. Meanwhile, the scientific communitys understanding of immune cells continued to advance. Orcas intellectual property covers both the cell therapy manufacturing technology, which offers the capability to sort stem and immune cells, and the therapeutic mixtures of cells. The startup spun out of Stanford in 2016 and started its first clinical trial about two years later, Dimov says.

Though cancer is Orcas focus for now, Dimov says the companys technology has potential applications in other diseases. Rare inherited disorders such as beta thalassemia and severe combined immunodeficiency are possible targets. Autoimmune diseases represent another opportunity. For each one, Orca would develop an appropriate mixture of immune and stem cells to treat the condition and restore immune system function, Dimov says.

Including the latest financing, Dimov says Orca has raised nearly $300 million. The new capital, a Series D round of funding, was co-led by Lightspeed Venture Partners and an unnamed investor. The other investors Orca has disclosed are 8VC, DCVC Bio, ND Capital, Abu Dhabi sovereign wealth fund Mubadala Investment Company, Kaiser Permanente, and the Illinois Municipal Retirement Fund.

Image: iStock/jonmccormackphoto

Frank Vinluan is an Xconomy editor based in Research Triangle Park. You can reach him at fvinluan@xconomy.com.

Original post:

Orca Bio Surfaces With $192M and Recipes for Custom Cell Therapies - Xconomy

Cell Therapy Manufacturing Market: Opportunities Forecast and Value Chain 2020-2030 – Cole of Duty

Prophecy Market Insights Cell Therapy Manufacturing market research report focuses on the market structure and various factors affecting the growth of the market. The research study encompasses an evaluation of the market, including growth rate, current scenario, and volume inflation prospects, based on DROT and Porters Five Forces analyses. The market study pitches light on the various factors that are projected to impact the overall market dynamics of the Cell Therapy Manufacturing market over the forecast period (2019-2029).

The data and information required in the market report are taken from various sources such as websites, annual reports of the companies, journals, and others and were validated by the industry experts. The facts and data are represented in the Cell Therapy Manufacturing report using diagrams, graphs, pie charts, and other clear representations to enhance the visual representation and easy understanding the facts mentioned in the report.

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The Cell Therapy Manufacturing research study contains 100+ market data Tables, Pie Chat, Graphs & Figures spread through Pages and easy to understand detailed analysis. The predictions mentioned in the market report have been derived using proven research techniques, assumptions and methodologies. This Cell Therapy Manufacturing market report states the overview, historical data along with size, share, growth, demand, and revenue of the global industry.

All the key players mentioned in the Cell Therapy Manufacturing market report are elaborated thoroughly based on R&D developments, distribution channels, industrial penetration, manufacturing processes, and revenue. Also, the report examines, legal policies, and competitive analysis between the leading and emerging and upcoming market trends.

Cell Therapy ManufacturingMarket Key Companies:

harmicell, Merck Group, Dickinson and Company, Thermo Fisher, Lonza Group, Miltenyi Biotec GmBH, Takara Bio Group, STEMCELL Technologies, Cellular Dynamics International, Becton, Osiris Therapeutics, Bio-Rad Laboratories, Inc., Anterogen, MEDIPOST, Holostem Terapie Avanazate, Pluristem Therapeutics, Brammer Bio, CELLforCURE, Gene Therapy Catapult EUFETS, MaSTherCell, PharmaCell, Cognate BioServices and WuXi AppTec.

Segmentation Overview:

Apart from key players analysis provoking business-related decisions that are usually backed by prevalent market conditions, we also do substantial analysis on market segmentation. The report provides an in-depth analysis of the Cell Therapy Manufacturing market segments. It highlights the latest trending segment and major innovations in the market. In addition to this, it states the impact of these segments on the growth of the market.

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Regional Overview:

The survey report includes a vast investigation of the geographical scene of the Cell Therapy Manufacturing market, which is manifestly arranged into the localities. The report provides an analysis of regional market players operating in the specific market and outcomes related to the target market for more than 20 countries.

Australia, New Zealand, Rest of Asia-Pacific

Key Questions Answered in Report:

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Cell Therapy Manufacturing Market: Opportunities Forecast and Value Chain 2020-2030 - Cole of Duty

Coronavirus: inside the UAE stem cell centre working to treat Covid-19 – The National

When Dr Yendry Ventura began work to set up the Abu Dhabi Stem Cell Centre in late 2018, there was, he says, nothing else "related to stem cell therapy in the emirate.

Fast forward to today and the situation has changed dramatically. After opening in December last year, the centre has already received international press coverage over to its research into a treatment for Covid-19.

Their groundbreaking work has involved taking stem cells from a patients blood and returning them, via a nebuliser, as a fine mist to the lungs.

There they help regenerate lung cells and improve the body's immune response by preventing an overreaction to the infection that can damage healthy cells.

What characterises the method, says Dr Ventura, is that very little manipulation of the cells is needed for the treatment to be effective.

The future for the stem cells lies in regenerative medicine, in which you can treat almost all the degenerative conditions.

Dr Yendry Ventura

We separate a specific layer of cells from the blood, Dr Ventura told The National. Were the first one to use these cells with this route with this method.

We believe this way the cells can be aimed much better to the affected organs - the upper and lower respiratory tract.

In April, the centres efforts to develop a Covid-19 treatment led to the recovery of all 73 patients the treatment was initially trialled on. A quarter had been in intensive care.

The results appeared so promising that this month the centre secured intellectual property rights to the technique, allowing the treatment to be widely licensed, including to facilities abroad.

The ongoing work exemplifies how the centres specialists have been able to apply their expertise to help in a time of crisis, Dr Ventura said.

But the new research is a departure from the facilitys usual purpose, which involves developing cutting-edge stem cell treatments for conditions such as cancer and heart disease.

Stem cells were first extracted from humans and grown in laboratories less than a quarter of a century ago.

The human body is mostly made of specialised cell types, such as heart muscle cells, kidney cells or nerve cells, all of which have a particular form related to their function.

Stem cells, however, have not yet undergone the process of developing into a specialised cell type, and are able to be manipulated to perform a specific function.

In adults, stem cells are found in tissues including fat and bone marrow, and these can be turned into cell types.

One technique that the Abu Dhabi Stem Cell Centre plans to implement is haematopoietic stem cell transplantation, which involves stem cells being removed from an individual who is due to have cancer treatment.

The cells are then processed in a laboratory and injected into the patient after they have undergone chemotherapy or radiotherapy.

In this way, they can replace stem cells destroyed by the treatment, allowing a patient to tolerate a higher dose of therapy.

Dr Ventura says that similar treatments were applicable to most cancers of the blood as well as cancers that produce solid tumours.

There are many of these therapies still in research stage, but if you conquer this research, you can have a programme in which you can ... treat many kinds of cancers at the same time in one centre, he said.

The reality is that cell therapy is curing cancer We need to improve this therapy and make it available for many other people.

The future for the stem cells lies in regenerative medicine, in which you can treat almost all the degenerative conditions.

You can create in the future, if you have the right technologies, even artificial organs.

Set up with private sector funding in collaboration with the UAE authorities, the Abu Dhabi Stem Cell Centre works closely with experts at Sheikh Khalifa Medical City.

But the institution is keen to forge further partnerships with both public and private sector medical institutions.

Currently, it operates seven days a week and has more than 100 staff, including nurses, technicians and doctors who specialise in immunology, haematology, pathology, orthopaedics, urology and radiology.

In another initiative, the facility has recently begun running Minimal Residual Disease tests, which look at how many malignant cells remain in a patients blood or bone marrow.

These tests are useful for people with a variety of blood cancers, including lymphoma, leukaemia and myeloma. But they require fresh samples from the patient, so the lack of UAE testing facilities has, until now, required patients to travel abroad.

We try to implement the tests here in the Abu Dhabi Stem Cell Centre so that the patient does not need to travel anymore, said Dr Ventura.

Updated: June 17, 2020 04:31 PM

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Coronavirus: inside the UAE stem cell centre working to treat Covid-19 - The National

Cell Therapy Manufacturing Market: Factory Price and Marginal Revenue Analysis by 2026 – Surfacing Magazine

Cell Therapy Manufacturing Market 2020 Global Industry Research report presents an in-depth analysis of the Cell Therapy Manufacturing market size, growth, share, segments, manufacturers, and technologies, key trends, market drivers, challenges, standardization, deployment models, opportunities, future roadmap and 2027 forecast.

Global Cell Therapy Manufacturing Market 2020 Industry Research Report is an expert and inside and out examination on the flow condition of the Global Cell Therapy Manufacturing industry. In addition, investigate report sorts the worldwide Cell Therapy Manufacturing market by top players/brands, area, type and the end client. This report likewise examines the different Factors impacting the market development and drivers, further reveals insight into market review, key makers, key received by them, size, most recent patterns and types, income, net edge with provincial examination and figure.

Read Summary Of Cell Therapy Manufacturing Market Report @Cell Therapy Manufacturing Market

List Of TOP KEY PLAYERS in Cell Therapy Manufacturing Market are: Pharmicell, Merck Group, Dickinson and Company, Thermo Fisher, Lonza Group, Miltenyi Biotec GmBH, Takara Bio Group, STEMCELL Technologies, Cellular Dynamics International, Becton, Osiris Therapeutics, Bio-Rad Laboratories, Inc., Anterogen, MEDIPOST, Holostem Terapie Avanazate, Pluristem Therapeutics, Brammer Bio, CELLforCURE, Gene Therapy Catapult EUFETS, MaSTherCell, PharmaCell, Cognate BioServices and WuXi AppTec.

Scope of Report:

The global Cell Therapy Manufacturing market is anticipated to rise at a considerable rate during the forecast period, between 2020 and 2027. In 2020, the market was growing at a steady rate and with the rising adoption of strategies by key players, the market is expected to rise over the projected horizon.

This report covers present status and future prospects for the Cell Therapy Manufacturing Market forecast till 2027. Market Overview, Development, and Segment by Type, Application and Region. Global Market by company, Type, Application and Geography. The report begins with an overview of the industry chain structure and describes the upstream. Besides, the report analyses Cell Therapy Manufacturing market trends, size and forecast in different geographies, type and end-use segment, in addition, the report introduces market competition overview among the major companies and companies profiles, besides, market price and channel features are covered in the report.

Cell Therapy Manufacturing Market Research Report provides exclusive vital statistics, data, information, trends and competitive landscape details in this niche sector.

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Brief Introduction to the research report.Table of Contents (Scope covered as a part of the study)Top players in the marketResearch framework (presentation)Research methodology adopted by Coherent Market Insights

Cell Therapy Manufacturing Market global industry research report is a professional and in-depth study on the market size, growth, share, trends, as well as industry analysis. According to the details of the consumption figures, the global Cell Therapy Manufacturing market forecast 2027.

Market by Region:

North America (U.S., Canada, Mexico)Europe (Germany, U.K., France, Italy, Russia, Spain etc.)Asia-Pacific (China, India, Japan, Southeast Asia etc.)South America (Brazil, Argentina etc.)The Middle East and Africa (Saudi Arabia, South Africa etc.)

Key Benefits For Stakeholders

Cell Therapy Manufacturing Market Taxonomy

On the basis of therapy type, the global cell therapy manufacturing market is segmented into:

On the basis of technology, the global cell therapy manufacturing market is segmented into:

On the basis of source, the global cell therapy manufacturing market is segmented into:

On the basis of application, the global cell therapy manufacturing market is segmented into:

On the basis of region, the global cell therapy manufacturing market is segmented into:

Main Aspects Covered In The Report:

Overview of the Cell Therapy Manufacturing market including production, consumption, status and forecast and market growth.Geographical analysis including major countries.Overview of the product type market including development.Overview of the end-user market including development.

Research Objectives:

To understand the structure of Cell Therapy Manufacturing market by identifying its various sub-segments.Focuses on the key global Cell Therapy Manufacturing manufacturers, to define, describe and analyze the sales volume, value, market share, market competition landscape, SWOT analysis and development plans in next few years. To analyze the Cell Therapy Manufacturing with respect to individual growth trends, future prospects, and their contribution to the total market. To share detailed information about the key factors influencing the growth of the market (growth potential, opportunities, drivers, industry-specific challenges and risks). To project the consumption of Cell Therapy Manufacturing submarkets, with respect to key regions (along with their respective key countries). To analyze competitive developments such as expansions, agreements, new product launches, and acquisitions in the market.To strategically profile the key players and comprehensively analyze their growth strategies.

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At last, the report gives the inside and out examination of Cell Therapy Manufacturing Market took after by the above components, which are useful for organizations or individuals for the development of their present business or the individuals who are hoping to enter in Cell Therapy Manufacturing industry.

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Cell Therapy Manufacturing Market: Factory Price and Marginal Revenue Analysis by 2026 - Surfacing Magazine

Efforts at coronavirus vaccines and treatments abound in the Bay Area – San Francisco Chronicle

The frenetic search for the miracle that will rid the world of COVID-19 is branching out in a thousand directions, and a large part of the microbial treasure hunt is going on in the Bay Area, where major progress has been made in the 100 days since residents were ordered to shelter in place.

Scientists at universities, laboratories, biotechnology companies and drug manufacturers are combing through blood plasma taken from infected patients for secrets that will help them fight the disease.

The key is likely a super-strength antibody found in some patients. But researchers must first figure out how those antibodies work and how they can be harnessed and used to stop the many health problems associated with COVID-19, particularly acute respiratory distress syndrome, or ARDS, which has killed more people than any other complication connected to the disease.

Other developments showing promise include injections of mesenchymal stem cells, found in bone marrow and umbilical cords, that doctors are studying to battle inflammation caused by ARDS. And a steroid called dexamethasone reduced the number of deaths by halting the overreactive immune responses in seriously ill patients in the United Kingdom.

In all, more than 130 vaccines and 220 treatments are being tested worldwide.

What follows is a list of some of the most promising elixirs, medications and vaccines with ties to the Bay Area:

Monoclonal antibodies / Vir Biotechnology, San Francisco: Scientists at Vir and several institutions, including Stanford and UCSF, are studying monoclonal antibodies, which are clones of coronavirus-fighting antibodies produced by COVID-19 patients.

The idea is to utilize these neutralizing antibodies which bind to the virus crown-like spikes and prevent them from entering and hijacking human cells.

Only about 5% of coronavirus patients have these super-strength antibodies, and those people are believed to be immune to a second attack.

The trick for scientists at Vir is to identify these neutralizing antibodies, harvest, purify and clone them. If they succeed, the resulting monoclones could then be used to inoculate people and it is hoped give them long-term immunity against the coronavirus. The company recently signed a deal with Samsung Biologics, in South Korea, to scale up production of a temporary vaccine in the fall after clinical trials are complete.

Another monoclonal antibody, leronlimab, is being studied in coronavirus clinical trials by its Washington state drugmaker, CytoDyn. The companys chief medical officer is in San Francisco, and the company that does laboratory tests of leronlimab is in San Carlos.

Interferon-lambda / Stanford University: Doctors at Stanford are running a trial to see if interferon-lambda, which is administered by injection, helps patients in the early stages of COVID-19. Interferon-lambda is a manufactured version of a naturally occurring protein that has been used to treat hepatitis. Stanford doctors hope it will boost the immune system response to coronavirus infections.

Dr. Upinder Singh, a Stanford infectious-disease expert, said the trial has enrolled more than 50 patients and is halfway finished. We have noted that patients tolerate the drug very well, she said.

Mesenchymal stem cells / UCSF and UC Davis Medical Center: UCSF Dr. Michael Matthay is leading a study about whether a kind of stem cell found in bone marrow can help patients with ARDS. Matthay hopes that the stem cells can help reduce the inflammation associated with some of ARDS most dire respiratory symptoms, and help patients lungs to recover.

Matthay is aiming to enroll 120 patients in San Francisco, the UC Davis Medical Center in Sacramento and hospitals in a handful of other states. He said the trial, which includes a small number ARDS patients who dont have COVID-19, should have results within a year. So far 17 patients are enrolled in the trial, most of them in San Francisco.

Remdesivir / Gilead Sciences (Foster City): Remdesivir, once conceived as a potential treatment for ebola, was the first drug to show some promise in treating COVID-19 patients. The drug interferes with the process through which the virus replicates itself. A large study led by the federal government generated excitement in late April when officials said hospitalized patients who received remdesivir intravenously recovered faster than those who received a placebo.

A later study looking at dosage showed some benefit for moderately ill COVID-19 patients who received remdesivir for five days, but improvement among those who got it for 10 days was not statistically significant. Gilead, a drug company, recently announced that it will soon launch another clinical trial to see how remdesivir works on 50 pediatric patients, from newborns to teenagers, with moderate to severe COVID-19 symptoms. More than 30 locations in the U.S. and Europe will be involved in the trial, the company said.

Coronavirus crisis: 100 days

Editors note: Its been 100 days since the Bay Area sheltered in place, protecting itself from the coronavirus pandemic. What have we learned in that time? And what does the future hold for the region and its fight against COVID-19? The Chronicle explores the past 100 days and looks to the future in this exclusive report.

Favipiravir / Fujifilm Toyama Chemical (Stanford University): This antiviral drug, developed in 2014 by a subsidiary of the Japanese film company to treat influenza, is undergoing numerous clinical studies worldwide, including a Stanford University trial that began this month. Unlike remdesivir, it can be administered orally, so it can be used to treat patients early in the disease, before hospitalization is necessary.

Stanford epidemiologists want to see if favipiravir, which has shown promising results in other trials, prevents the coronavirus from replicating in human cells, halts the shedding of the virus and reduces the severity of infection. The Stanford study, the only outpatient trial for this drug in the nation, is enrolling 120 people who have been diagnosed with COVID-19 within the past 72 hours. Half of them will get a placebo. People can enroll by emailing treatcovid@stanford.edu.

Colchicine / UCSF (San Francisco and New York): The anti-inflammatory drug commonly used to treat gout flare-ups is being studied in the U.S. by scientists at UCSF and New York University. The drug short-circuits inflammation by decreasing the bodys production of certain proteins, and researchers hope that it will reduce lung complications and prevent deaths from COVID-19. About 6,000 patients are receiving colchicine or a placebo during the clinical trial, dubbed Colcorona, which began in March and is expected to be completed in September.

Selinexor / Kaiser Permanente: Kaiser hospitals in San Francisco, Oakland and Sacramento are studying selinexor, an anticancer drug that blocks a key protein in the cellular machinery for DNA processing, as a potential COVID-19 treatment. The drug has both antiviral and anti-inflammatory properties, and its administered orally, according to Kaisers Dr. Jacek Skarbinski. The trial aims to enroll 250 patients with severe symptoms at Kaiser and other hospitals that are participating nationwide.

VXA-COV2-1 / Vaxart, South San Francisco: The biotechnology company Vaxart is testing this drug to see if it is as effective at controlling COVID-19 as trials have shown it to be against influenza. VXA-COV2-1, the only potential vaccine in pill form, uses the genetic code of the coronavirus to trigger a defensive response in mucous membranes. The hope is that the newly fortified membranes will prevent the virus from entering the body.

Its the only vaccine (candidate) that activates the first line of defense, which is the mucosa, said Andrei Floroiu, Vaxarts chief executive, noting that intravenous vaccines kill the virus after it is inside the body. Our vaccine may prevent you from getting infected at all.

The drug was effective against influenza and norovirus in trials and appears to work on laboratory animals, Floroiu said. He expects trials of VXA-COV2-1 on humans to begin later this summer.

VaxiPatch / Verndari (Napa and UC Davis Medical Center): Napa vaccine company Verndari makes a patented adhesive patch that can deliver a vaccine instead of a shot. Now, the company is trying to make a vaccine for COVID-19 that they can administer through that patch. At UC Davis Medical Center in Sacramento, Verndari researchers are developing a potential vaccine that relies on the coronavirus spike-shaped protein. When injected into a person, the substance would ideally train their body to recognize the virus and fight it off without becoming ill.

A spokeswoman told The Chronicle that the companys preclinical tests have shown early, positive data in developing an immune response. Verndari hopes to move into the next phase of testing in the coming weeks and start clinical trials in humans this year.

If the vaccine is proved effective and safe, patients could receive it through the mail, according to company CEO Dr. Daniel Henderson. The patch would leave a temporary mark on the skin that patients could photograph and send to their doctor as proof they have taken the vaccine, Henderson has said.

Peter Fimrite and J.D. Morris are San Francisco Chronicle staff writers. Email: pfimrite@sfchronicle.com, jd.morris@sfchronicle.com Twitter: @pfimrite, @thejdmorris

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Efforts at coronavirus vaccines and treatments abound in the Bay Area - San Francisco Chronicle

NIH announces new Transformative Research Award program for ALS – National Institutes of Health

News Release

Wednesday, June 17, 2020

New initiative encourages innovative research on devastating neurological disease.

The National Institutes of Health plans to invest $25 million over five years in a new program to spur innovative research on amyotrophic lateral sclerosis (ALS), a progressive and fatal neurological disease that weakens and eventually paralyzes voluntary muscles. Accelerating Leading-edge Science in ALS (ALS2) aims to answer critical questions about this disease.

Over the past few decades, there has been significant progress in our understanding of ALS, but we still do not have any breakthrough treatments for this terrible disease, said NIH Director Francis S. Collins, M.D., Ph.D. We hope this program will inject new ideas to the field to push us rapidly toward effective therapies.

Sometimes known as Lou Gehrigs disease, ALS is a neurodegenerative disease that affects motor neurons in the spinal cord that control voluntary muscles. For reasons that are currently unknown, the motor neurons die off, resulting in progressive muscle weakness that usually leads to respiratory failure. ALS is virtually always fatal, and many people die within three to five years of developing symptoms.

There is no cure for ALS. The U.S. Food and Drug Administration-approved drugs riluzole and edaravone can prolong life by a few months but do not improve symptoms. Ongoing clinical trials are looking at a range of therapeutic strategies including new drug candidates, devices to improve quality of life, and stem cell therapies. Genetic research has recently provided clues to understanding the disease, but it will take a focused investment in research from a range of scientific disciplines in order to capitalize on these insights.

ALS2 will be part of the NIH Common Funds High-Risk, High-Reward (HRHR) research program. The four initiatives of the HRHR program are a time-tested, powerful approach to sparking innovation. They support exceptionally creative research, which is inherently riskier, but has the potential to transform biomedical science. NIH will apply this potential to ALS2 through the HRHR programs Transformative Research Award initiative. The Transformative Research Award is particularly well-suited to interdisciplinary teams of scientists looking to combine their expertise and pursue new ideas with the potential to transform ALS research.

ALS2 will take a three-pronged approach to improve understanding of ALS:

Information on a Notice of Special Interest to accompany the Transformative Research Award funding opportunity will be posted here: https://commonfund.nih.gov/tra/grants.

This initiative is managed collaboratively by the NIH Common Fund, the National Institute of Neurological Disorders and Stroke, the National Institute on Aging, the National Institute of Environmental Health Sciences, and the National Institute of General Medical Sciences.

About the National Institutes of Health (NIH):NIH, the nation's medical research agency, includes 27 Institutes and Centers and is a component of the U.S. Department of Health and Human Services. NIH is the primary federal agency conducting and supporting basic, clinical, and translational medical research, and is investigating the causes, treatments, and cures for both common and rare diseases. For more information about NIH and its programs, visit http://www.nih.gov.

NIHTurning Discovery Into Health

###

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NIH announces new Transformative Research Award program for ALS - National Institutes of Health

Global Animal Stem Cell Therapy Market Report 2020 Cole Reports – Cole of Duty

The report delivers the driving factors, challenges, restraints, opportunities, acquisition & merger, revenue structure, business models, market players, segmentation, regional analysis, production price, manufacturing process, operations, methodology, market share, market size, CAGR, and investments.

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Manufacturer Detail

Manufacturer DetailMedivet Biologics LLCVETSTEM BIOPHARMAJ-ARMU.S. Stem Cell, IncVetCell TherapeuticsCelavet Inc.Magellan Stem CellsKintaro Cells PowerAnimal Stem CareAnimal Cell TherapiesCell Therapy SciencesAnimacel

BIS reports covers key roles in analyzing the industry outlook and let understand the prominent vendors about their strategies and future plans for the betterment of the market in the near future. Furthermore, the report also covers an ultimate goal of market target gained on the basis of product or services. In this Animal Stem Cell Therapy market report, viewers can also experience detailed study of business introduction including benefits, restraints, opportunities, challenges, drivers, and more. The report smartly takes you to productive methodology in organizing, collection, and analyzing data. The report covers key aspects including production, market share, CAGR, key regions, leading vendors, and revenue rates. This keyword report also provides viewers with relevant figures at which the Animal Stem Cell Therapy market was valued in the base year and estimated to project the revenue in the forecasted period. The Animal Stem Cell Therapy market is categorizes several segmentations including type, application, end user industry, and region. This effective set of information delivers an in-depth analysis about the drivers, challenges, market share, market dynamics, emerging countries, pricing, investment activity, industry performance, revenue generation and CAGR.

Region Segmentation

North America Country (United States, Canada)South AmericaAsia Country (China, Japan, India, Korea)Europe Country (Germany, UK, France, Italy)Other Country (Middle East, Africa, GCC)

Product Type SegmentationAlN-170 AlN Ceramic SubstratesAlN-200 AlN Ceramic SubstratesOthers, like AlN-180 and AlN-230 etc.Industry SegmentationIGBTLED

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Channel (Direct Sales, Distributor) Segmentation

Section 8: 400 USDTrend (2019-2024)

Section 9: 300 USDProduct Type Detail

Section 10: 700 USDDownstream Consumer

Section 11: 200 USDCost Structure

Section 12: 500 USDConclusion

The research report is an overall draft when it comes to understand the investment structure and future analysis of the Animal Stem Cell Therapy market. BIS Report manages to convey detailed information regarding prominent vendors of the Animal Stem Cell Therapy market including recent innovations, advancements, improvements, business estimation, revenue margin, and sales graph.

Consumer-wise, the report studies about the demand coming from particular region and category of consumers taking interest in the product or services of the Animal Stem Cell Therapy market. The global keyword market is majorly driven by key factors and offers an in-depth insight about the keyword market.

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The Animal Stem Cell Therapy market reports delivers the information about market competition between vendors through regional segmentation of markets in terms of business opportunities, demand & supply, and revenue generation potential.

BIS report envision clear view about Animal Stem Cell Therapy market including regional growth and falls down mentioning about particular forecast period along with appropriate reasoning about the market.

The Animal Stem Cell Therapy market also delivers the market size, market appearances, segmentation, provincial collapses, tendencies, competitive background to gain the appropriate insights. Moreover, the report also covers about the acquisitions and mergers taken in the recent past.

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Orbis Research (orbisresearch.com) is a single point aid for all your market research requirements. We have vast database of reports from the leading publishers and authors across the globe. We specialize in delivering customized reports as per the requirements of our clients. We have complete information about our publishers and hence are sure about the accuracy of the industries and verticals of their specialization. This helps our clients to map their needs and we produce the perfect required market research study for our clients.

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Global Animal Stem Cell Therapy Market Report 2020 Cole Reports - Cole of Duty

Cell Therapy Market 2020 by Product-Types, Market Dynamics, Application, Growth Prospects, Top Players Analysis and Demand Insights 2025 – Owned

Global Cell Therapy Market report shows the Industry Chain Structure as well as Macroeconomic Environment Analysis and Development Trend. The Cell Therapy Market report also provides the market impact and new opportunities created due to the COVID19/CORONA Virus catastrophe. The total market is further divided by company, by country, and by application/types for the competitive landscape analysis. The report then estimates 2020-2025 market development trends of Cell Therapy Industry.

Top Leading Key Players are:

JCR Pharmaceuticals Co., Ltd., Kolon TissueGene, Inc.; and Medipost and many more.

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Initially, the report provides a basic overview of the industry including definitions, classifications, applications, and industry chain structure. The Cell Therapy market analysis is provided for the international markets including development trends, competitive landscape analysis, and key regions development status.

The report introduces Cell Therapy basic information including definition, classification, application, industry chain structure, industry overview, policy analysis, and news analysis. Insightful predictions for the Cell Therapy market for the coming few years have also been included in the report.

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Global Cell Therapy market is segmented based by type, application and region.

Based on Type, the market has been segmented into:

By Use & Type Outlook, (Clinical-use,By Cell Therapy Type,,Non-stem Cell Therapies,Stem Cell Therapies,BM, Blood, & Umbilical Cord-derived Stem Cells,Adipose derived cells,Others), By Therapeutic Area, (Malignancies,Muscoskeletal Disorders,Autoimmune Disorders,Dermatology,Others,Research-use), By Therapy Type, (Allogenic Therapies,Autologous Therapies)

The report focuses on global major leading Cell Therapy Market players providing information such as company profiles, product picture and specification, capacity, production, price, cost, revenue and contact information. Upstream raw materials and equipment and downstream demand analysis is also carried out.

The Cell Therapy industry development trends and marketing channels are analyzed. Finally, the feasibility of new investment projects is assessed, and overall research conclusions offered.

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Adroit Market Research is an India-based business analytics and consulting company. Our target audience is a wide range of corporations, manufacturing companies, product/technology development institutions and industry associations that require understanding of a markets size, key trends, participants and future outlook of an industry. We intend to become our clients knowledge partner and provide them with valuable market insights to help create opportunities that increase their revenues. We follow a code Explore, Learn and Transform. At our core, we are curious people who love to identify and understand industry patterns, create an insightful study around our findings and churn out money-making roadmaps.

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Cell Therapy Market 2020 by Product-Types, Market Dynamics, Application, Growth Prospects, Top Players Analysis and Demand Insights 2025 - Owned

FTC Sends Letters Warning Marketers to Stop Making Unsupported Claims That Their Products and Therapies Can Effectively Prevent or Treat COVID-19 …

June 22, 2020 - The Federal Trade Commission announced it has sent letters warning 30 more marketers nationwide to stop making unsubstantiated claims that their products and therapies can treat or prevent COVID-19, the disease caused by the novel coronavirus. This is the seventh set of warning letters the FTC has announced as part of its ongoing efforts to protect consumers from health-related COVID-19 scams. In all, the Commission has sentsimilar letters to 250 companies and individuals.

Most of the letters announced today target treatments the FTC has warned companies about previously, including intravenous (IV) Vitamin C and D infusions, supposed stem cell therapy, vitamin injections, essential oils, and CBD products. Other letters sent recently challenged claims that infrared heat, oral peroxide gel, and oxygen therapy can treat or cure COVD-19. However, currently there is no scientific evidence that these, or any, products or services can treat or cure the disease.

The FTC sent the letters announced today to the companies and individuals listed below. The recipients are grouped based on the type of therapy, product, or service they pitched as preventing or treating COVID-19.

CBD:

Essential Oils:

Infrared Heat:

Intravenous (IV) Vitamin and Ozone/Oxygen Therapies:

Oral Peroxide Gel:

Pulsed Electromagnetic Field Therapy:

Stem Cell Treatments:

Supplements, Vitamins, and Colloidal Silver:

In the letters, the FTC states that one or more of the efficacy claims made by the marketers are unsubstantiated because they are not supported by scientific evidence, and therefore violate the FTC Act. The letters advise the recipients to immediately stop making all claims that their products can treat or cure COVID-19, and to notify the Commission within 48 hours about the specific actions they have taken to address the agencys concerns.

The letters also note that if the false claims do not cease, the Commission may seek a federal court injunction and an order requiring money to be refunded to consumers. In April, the FTC announced itsfirst case against a marketer of such products, Marc Ching, doing business as Whole Leaf Organics.

The FTC worked in coordination with the Office of the Attorney General of Louisiana, on the warning letter to The Remedy Room, and appreciates its assistance.

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FTC Sends Letters Warning Marketers to Stop Making Unsupported Claims That Their Products and Therapies Can Effectively Prevent or Treat COVID-19 ...

COVID 19 to Lead the Sales of Non-Union Fractures to Register Stellar Growth in the Next 10 Years – Cole of Duty

Nonunion bone fracture is changeless disappointment of recuperating following a broken bone unless intercession, (for example, surgery) is performed. Nonunion fractures can be categorized into hypertrophic (generally due to mechanical failure/ callus formation) and atrophic (generally due to organic failure/ no callus and bone resorption). A delayed or with nonunion fracture forms a structural resemblance to a fibrous joint, and is therefore often called pseudoarthrosis. Nonunion fracture is a genuine complexity of a bone fracture and may happen when the bone moves excessively, has a poor blood supply or gets infected. Patients who smoke have a higher occurrence of nonunion fractures. The ordinary procedure of bone recuperating is hindered or slowed down. A nonunion or delayed fracture may go ahead to recuperate without mediation in many cases. In normal, if a nonunion is as yet obvious at a half year post damage it will stay unhealed without particular treatment, generally orthopedic surgery. The revision surgical intervention is the common methodology utilized, treatment via stem cell therapies is also on a rise, such as, Regenexx stem cell procedure. The explanations for a non-union fracture may comprise: complicated, multisegmental fractures (severe comminution), open fractures, fractures associated with tumors (pathologic fractures), infection, inadequate fracture immobilization (fixation), inadequate blood supply, poor nutrition, and chronic disease states (diabetes, renal failure, metabolic bone disease).

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Factors Driving Non-union fractures

Increasing sports related injuries and mechanical injuries, diabetic population, obesity, bone infection, poor nutrition and rising pathologic fractures among geriatric individuals is going to spur revenue growth for global non-union fractures market. In the US, there are roughly seven million new fractures which occur every year, with around 300,000 growing gradually. Appraisals for the normal non-union fracture associated treatment cost shift from almost $25,000 to $45,000. Non-unions are assessed to cost the healthcare services in the US $9.2 billion/year. This prohibits losses in profitability to the economy.

Rising Associated Cost for Non-union fractures Treatment

In the UK, there are around 850,000 new bone fractures seen every year. While it has been recommended that roughly 5-10% of such fractures are fractures in which the broken bone neglects to recuperate, medicinally alluded to as nonunion bone fractures. The cost to the National Health Service of treating non-union bone fractures has been accounted for to go amongst 18,000 and 79,000 per individual. The evaluated addressable market for nonunion and improved recuperating of bone fractures for the EU is around 0.7 to 2 Bn Euros for each year, expecting a cost of roughly 2,000 to 2,500 Euro for every treatment regimen. Normal direct expenses of treatment for a built up long bone non-union have been accounted for: Canada, $11,800; the USA $11,333; the UK 29,204.

Market Segmentation:

By Treatment Type

By Indication

Competition Outlook

Examples of some of the key participants in the non-union fractures market are Daniel C. Allison, Regenexx, Kalytera Therapeutics, Inc., ASA srl, Mesentech, EnteraBio Ltd. and others.

Regional Market Outlook

Globally, around 50 Mn bone fractures occur worldwide consistently. Osteoporosis is the most widely recognized reason for bone fractures and the commonness of osteoporosis and low bone mass is required to increment in coming a very long time due basically to the geriatric and matured population. Roughly 33% of all tibia and femoral shaft bone fractures have deferred rates of recuperating or non-healing. Patients with postponed union or non-union can expect poorer results, including expanded pain, loss of overall functionality, loss of personal satisfaction, and deferral consequently to work. There are as of now restricted treatment alternatives accessible for enhancing the rate of bone healing and bone fracture repair.

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Anabolic specialists and bone morphogenetic proteins, including teriparatide, are exorbitant and may need wanted viability; enhanced therapeutic or remedial choices are desired. On the basis of geography, the global non-union fractures market can be segmented into five key regions viz. North America, Latin America, Europe, Asia Pacific, and the Middle East & Africa. North America and Europe collectively are expected to dominate the global non-union fractures market due to increasing awareness and inclination of treatment options coupled with stem cell therapy management. However, APAC is expected to grow at a sluggish rate in the global market due to their low adoption, though with large patient pool. The Middle East & Africa to adopt this advanced technology lately due to less awareness and less reach of the product due to less geographical presence of the players.

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COVID 19 to Lead the Sales of Non-Union Fractures to Register Stellar Growth in the Next 10 Years - Cole of Duty

COVID-19: Potential impact on Musculoskeletal Disorder Stem Cell Therapy Market Estimated to Record Highest CAGR by 2019-2025 – Personal Injury Bureau…

The global Musculoskeletal Disorder Stem Cell Therapy market study presents an all in all compilation of the historical, current and future outlook of the market as well as the factors responsible for such a growth. With SWOT analysis, the business study highlights the strengths, weaknesses, opportunities and threats of each Musculoskeletal Disorder Stem Cell Therapy market player in a comprehensive way. Further, the Musculoskeletal Disorder Stem Cell Therapy market report emphasizes the adoption pattern of the Musculoskeletal Disorder Stem Cell Therapy across various industries.

The Musculoskeletal Disorder Stem Cell Therapy market report examines the operating pattern of each player new product launches, partnerships, and acquisitions has been examined in detail.

The report on the Musculoskeletal Disorder Stem Cell Therapy market provides a birds eye view of the current proceeding within the Musculoskeletal Disorder Stem Cell Therapy market. Further, the report also takes into account the impact of the novel COVID-19 pandemic on the Musculoskeletal Disorder Stem Cell Therapy market and offers a clear assessment of the projected market fluctuations during the forecast period.

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segment by Type, the product can be split intoAllogeneicAutologousMarket segment by Application, split intoMuscle diseaseSkeletal disease

Market segment by Regions/Countries, this report coversNorth AmericaEuropeChinaJapanSoutheast AsiaIndiaCentral & South America

The study objectives of this report are:To analyze global Musculoskeletal Disorder Stem Cell Therapy status, future forecast, growth opportunity, key market and key players.To present the Musculoskeletal Disorder Stem Cell Therapy development in North America, Europe, China, Japan, Southeast Asia, India and Central & South America.To strategically profile the key players and comprehensively analyze their development plan and strategies.To define, describe and forecast the market by type, market and key regions.

In this study, the years considered to estimate the market size of Musculoskeletal Disorder Stem Cell Therapy are as follows:History Year: 2015-2019Base Year: 2019Estimated Year: 2020Forecast Year 2020 to 2026For the data information by region, company, type and application, 2019 is considered as the base year. Whenever data information was unavailable for the base year, the prior year has been considered.

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The Musculoskeletal Disorder Stem Cell Therapy market report offers a plethora of insights which include:

The Musculoskeletal Disorder Stem Cell Therapy market report answers important questions which include:

The Musculoskeletal Disorder Stem Cell Therapy market report considers the following years to predict the market growth:

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Why Choose Musculoskeletal Disorder Stem Cell Therapy Market Report?

Musculoskeletal Disorder Stem Cell Therapy Market Reportfollows a multi- disciplinary approach to extract information about various industries. Our analysts perform thorough primary and secondary research to gather data associated with the market. With modern industrial and digitalization tools, we provide avant-garde business ideas to our clients. We address clients living in across parts of the world with our 24/7 service availability.

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COVID-19: Potential impact on Musculoskeletal Disorder Stem Cell Therapy Market Estimated to Record Highest CAGR by 2019-2025 - Personal Injury Bureau...

Regenerative Medicine Market Key Trends, Growth, Share, Size, Analysis and Forecast to 2023 – 3rd Watch News

Premium market insights delivers well-researched industry-wide information on the Regenerative Medicine market. It studies the markets essential aspects such as top participants, expansion strategies, business models, and other market features to gain improved market insights. Additionally, it focuses on the latest advancements in the sector and technological development, executive tools, and tactics that can enhance the performance of the sectors.

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Scope of the Report

The global regenerative medicine market was valued at $5,444 million in 2016, and is estimated to reach $39,325 million by 2023, registering a CAGR of 32.2% from 2017 to 2023. Regenerative medicines repair, replace, and regenerate tissues and organs affected due to injury, disease, or natural ageing process. These medicines help restore the functionality of cells & tissues and are applicable in numerous degenerative disorders such as dermatology, neurodegenerative diseases, cardiovascular, and orthopedic applications. Researchers focus on developing technologies based on biologics, genes, somatic as well as stem cells. Stem cells are capable of proliferation and differentiation and hence, are critical in this field.

The major factors that boost the market growth include technological advancements in tissue and organ regeneration, increase in prevalence of chronic diseases and trauma emergencies, prominent potential of nanotechnology, and emergence of stem cell technology. In addition, rise in degenerative diseases and shortage of organs for transplantation are expected to fuel the growth of the market. Moreover, utilization of nanomaterials in wound care, drug delivery, and immunomodulation has opened numerous growth avenues for the regenerative medicines market. However, stringent regulatory barriers and high cost of the treatment are likely to hinder the market growth.

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Top Key Players:

KEY MARKET BENEFITS FOR STAKEHOLDERS

This report offers a detailed quantitative analysis of the market trends from 2016 to 2023 to identify the prevailing opportunities.

The market estimations provided in this report are based on a comprehensive analysis of the key developments in the industry.

An in-depth analysis based on geography facilitates the study of the regional market to assist in strategic business planning.

The development strategies adopted by the key manufacturers are enlisted in the report to understand the competitive scenario of the market.

KEY MARKET SEGMENTS

By Product Type

Cell Therapy

Gene Therapy

Tissue Engineering

Small Molecule & Biologic

By Material

Synthetic Material

Biodegradable Synthetic Polymer

Scaffold

Artificial Vascular Graft Material

Hydrogel Material

Biologically Derived Material

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Geographically, this report focuses on product sales, value, market share, and growth opportunity in key regions such as United States, Europe, China, Japan, Southeast Asia, and India.

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Regenerative Medicine Market Key Trends, Growth, Share, Size, Analysis and Forecast to 2023 - 3rd Watch News