Research by the Montana Center for Work Physiology and Exercise Metabolism Proves Heat Stroke Death Can Occur Even …

Missoula, MT (PRWEB) May 29, 2013

Each year, more than 1,000 people die from heat stroke in the United States. Long thought to be the product of dehydration, traditional prevention and treatment of heat related illness has been to drink more water. More recent research by the University of Montana's Center for Work Physiology and Exercise Metabolism (Montana WPEM) has proven that, while proper hydration is important, the key step to preventing heat stroke is to recognize when one is working too hard for the given environment and slowing down or stopping.

One can absolutely suffer and even die from heat stroke even when properly hydrated, said Dr. Brent Ruby, Director of Montana WPEM. Prevention of heat stroke starts with recognizing our own limits while being active in hot environments. Our bodies are sending us signals to slow down and stop; we just have to know when to say when.

The first stage of heat related illness is heat cramps with symptoms including painful muscle aches. The next stage is heat exhaustion with symptoms such as headache, nausea, dizziness, weakness, irritability, thirst and heavy sweating. Without taking steps to cool down, heat exhaustion can quickly progress to heat stroke when the body becomes overwhelmed by heat and is unable to regulate its core temperature. Symptoms of heat stroke include, sweating stops and the victim may become confused, lose consciousness, and have seizures. Heat stroke is a medical emergency that may result in death.

In cases of HRI (heat related illness) that are developed during exertional heat stress, the individual is working too hard for the environment they are in and likely thinks -- if I can stay hydrated, I will be fine, explained Ruby. But, thats the wrong thinking. Even aggressive hydration strategies that attempt to match fluid loss one-to-one will not prevent the HRI. Knowing when to stop is the crucial step in prevention of heat stroke.

Dr. Brent Ruby, Ph.D., FACSM is Director of the Montana Center for Work Physiology and Exercise Metabolism (Montana WPEM) at the University of Montana and a fellow of the American College of Sports Medicine (ACSM). Dr. Rubys research interests include nutritional strategies during ultra-endurance work/competition, muscle metabolism during and after exercise, the use of stable isotope tracers for the measure of water turnover and energy expenditure, and issues surrounding heat stress during arduous work. Differentiating Montana WPEM from other labs, Ruby created a solar powered, mobile lab that allows controlled laboratory research to be meshed with raw field data to draw scientific conclusions.

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Research by the Montana Center for Work Physiology and Exercise Metabolism Proves Heat Stroke Death Can Occur Even ...

US medical company patents basic aspect of human physiology crucial to IVF treatment

Auxogyn and Stamford University face criticism from leading embryologist.

A donated human embryo is seen through a microscope. Photograph: Getty Images

The US has granted a patent to a biotechnology company Auxogyn covering data about cell cycles which at least one leading embryologist believes is a basic aspect of human physiology.

Jacques Cohen, a Dutch embryologist best known for being the first to successfully freeze and thaw a human embryo for use in IVF, accused the company, as well as Stanford University, of "claiming aspects of natural processes in embryos as property", calling it "an outrageous attempt to over-commercialise every step of an already expensive medical procedure".

The Guardian's Robin McKie explains the data which is now protected:

The use of cell-cycle timing data to make dramatic improvements in IVF success rates was recently outlined in the UK. By studying the time embryos take to develop, researchers could pick the best ones to be implanted into the womb. To do this, thousands of pictures are taken during the first few days of an IVF embryo's life. Implantation success rates could triple because of this work, researchers said.

The patent means that, in the US at least, IVF procedures will either get more expensive or their efficacy will be limited. But more than that, it's controversial because the information is an inherent aspect of human physiology making it difficult to think of it as a medical "invention".

The controversy follows on from the row over the patents granted to Myriad Genetics over certain mutations of the genes BRCA1 and BRCA2. Those mutations are strong markers of cancer risk in women, and Angelina Jolie's notable decision to have a preventative double mastectomy was based on a test revealing that she was a carrier. But the licensing fees for the test push its cost up to over $3000, while the actual test itself could be done for as little as $99.

Myriad Genetics patents were taken to court, after activists argued that it was illegal to take ownership of human genes. The company won the case in the US Court of Appeals, however, after it argued that the patent is technically over the "isolated" DNA molecules. Since those isolated genes would never exist if they weren't removed from the chromosome by the test, the judge concurred that "each of the claimed molecules represents a nonnaturally occurring composition of matter." The case is now being appealed to the Supreme Court.

Whether Auxogyn will be able to make a similar argument in court or whether attempts to fight the patent will even make it to court remains to be seen. But it looks more and more likely that Myriad Genetics patents were not a one-off, and were instead the beginning of a concerning trend.

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US medical company patents basic aspect of human physiology crucial to IVF treatment

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