Hyper-real Insect Design with Eric Keller – Video


Hyper-real Insect Design with Eric Keller
Hyper-real Insect Design with Eric Keller http://www.thegnomonworkshop.com In this DVD Eric Keller demonstrates his process for designing, modeling, and rendering an original photo realistic insect using ZBrush 4 R4, Photshop, Maya, and V-Ray. Eric talks about how he relies on insect physiology and evolutionary biology as guidelines for his original concept and how to bring photo reference directly into ZBrush using Spotlight. Eric takes the design from basic blockout using dynamesh all the way to completed model. Eric demonstrates the new topology tools of ZBrush 4 R 4 as well as how to generate UV texture coordinates. The model is brought into Maya and prepared for rendering. Eric discusses displacement and bump map set up in VRay, how to create custom materials, and how to set up the VRay Physical camera to create the look of macro photography.From:thegnomonworkshopViews:2 0ratingsTime:02:03More inEducation

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Hyper-real Insect Design with Eric Keller - Video

ZIOPHARM Oncology Presents Systemic, DNA/Cell Plasmid Therapy Showing Long-Term Persistence and Anti-Tumor Effects at …

NEW YORK, Nov. 7, 2012 (GLOBE NEWSWIRE) -- ZIOPHARM Oncology, Inc. (ZIOP), a drug development company employing small molecule and synthetic biology approaches to cancer therapy, announced today results from a preclinical study demonstrating the long-term persistence and anti-tumor effects of a new synthetic biology approach (DNA/cell plasmid) to controlled protein production in vivo. This embedded controlled bioreactor study was presented at the EORTC-NCI-AACR International Conference on Molecular Targets and Cancer Therapeutics, taking place November 6-9 in Dublin, Ireland, and was conducted jointly by ZIOPHARM and Intrexon Corporation, a synthetic biology company that utilizes its proprietary technologies to provide control over cellular function, ZIOPHARM's exclusive channel partner for the development of DNA therapeutics.

"These data demonstrate the potential of our disruptive technologies, including UltraVector(R), RTS(R), and our cell engineering capabilities," said Samuel Broder, M.D., Chairman of Intrexon's Therapeutic Opportunities Committee and former Director of the NCI (National Cancer Institute). "By using tightly controlled, purpose-built, cellular protein factories, we open up therapeutic windows for a broad array of proteins. This study demonstrates the long-term persistence of this approach, with sustained protein production and therapeutic anti-tumor efficacy drawing from only a single intramuscular administration of plasmid DNA."

Hagop Youssoufian, M.D., President of Research and Development and Chief Medical Officer of ZIOPHARM, said, "These data are very exciting, as they provide us with another systemic approach for the delivery of therapeutic proteins to a target cancer using engineered DNA transgenes. We have already seen the potential in the clinic of delivering these transgenes using dendritic cells and viral vectors. Each approach gives us a means of optimizing the timing, concentration and location of therapeutic proteins; ultimately allowing us to dislocate cancer's signaling networks with minimal interference to our natural systems. We look forward to further our study of therapeutic anti-cancer proteins delivered via this revolutionary technology."

For this study, a RheoSwitch(R)-regulated (RTS(R)) interferon alpha (IFN) plasmid transgene was evaluated as a means of widening the therapeutic window of IFN in a melanoma mouse model. DNA vectors for the controlled expression of murine or human IFN were optimized using Intrexon's UltraVector(R) platform, then transfected into human fibrosarcoma cells or myoblasts, forming RTS-IFN plasmids. These plasmids were subsequently electroporated into the skeletal muscle of normal or melanoma tumor-bearing mice, and then activated using an oral activator ligand (AL).

A single intramuscular electroporation of RTS-IFN combined with daily oral activator ligand treatment led to significant tumor growth inhibition, comparable to chemotherapy or repeated bolus injection with recombinant mIFN protein, but without overt toxicity, as assessed by body weight change and survival. Treatment with pRTS-IFN resulted in sustained serum and tumor expression of mouse IFN for approximately 4 months (study termination), as well as expression of the angiogenic biomarker IP-10, and activation of T cells (CD4 and CD8), NK cells, and dendritic cells.

About ZIOPHARM Oncology, Inc.:

ZIOPHARM Oncology is a biopharmaceutical company focused on the development and commercialization of new cancer therapies. The Company's clinical programs include:

Palifosfamide (ZIO-201) is a potent bi-functional DNA alkylating agent that has activity in multiple tumors by evading typical resistance pathways. Palifosfamide is in the same class as bendamustine, cyclophosphamide, and ifosfamide. Intravenous palifosfamide is currently being studied in a randomized, double-blinded, placebo-controlled Phase 3 trial (PICASSO 3) for the treatment of first-line metastatic soft tissue sarcoma and is also in a pivotal Phase 3 trial (MATISSE) for first-line metastatic small cell lung cancer. Additionally, the Company is developing an oral capsule form of palifosfamide.

Ad-RTS IL-12 is currently being tested in a Phase 2 study. Ad-RTS IL-12 uses synthetic biology to enable controlled, local delivery of therapeutic interleukin-12 (IL-12), a protein important for an immune response to cancer. ZIOPHARM's DNA synthetic biology platform is being developed in partnership with Intrexon Corporation and employs an inducible gene-delivery system that enables controlled, local delivery of genes that produce therapeutic proteins to treat cancer. This is achieved by placing IL-12 under the control of Intrexon's proprietary biological "switch" (the RheoSwitch Therapeutic System(R), RTS(R)) to turn on/off the therapeutic protein expression at the tumor site.

Indibulin (ZIO-301) is a novel, tubulin binding agent that is expected to have several potential benefits, including oral dosing, application in multi-drug resistant tumors, no neuropathy and a tolerable toxicity profile. It is currently being studied in a Phase 1/2 trial in metastatic breast cancer.

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ZIOPHARM Oncology Presents Systemic, DNA/Cell Plasmid Therapy Showing Long-Term Persistence and Anti-Tumor Effects at ...

DuPont, CSHL Extend Plant Biology Research Alliance

The Institute of Medicine of the National Academy of Sciences has elected 70 new members including Lynda Chin, Stephen Quake, and Daniel Kastner. Chin is currently a professor and chair of genomic medicine and scientific director of the Institute for Applied Cancer Science at the University of Texas MD Anderson Cancer Center. Quake is a professor of bioengineering at Stanford University and an investigator at the Howard Hughes Medical Institute. Kastner is the scientific director of the National Human Genome Research Institute, where, among other duties, he leads the inflammatory disease section of the medical genetics branch.

Caprotec Bioanalytics has appointed Jonathan Turner to be CEO and managing director. Turner will take over the CEO spot from company founder Hubert Koester, who will continue to work with the company as acting chief scientific officer and chairman of the scientific advisory board. Turner formerly was senior VP at XL Techgroup, a technology developer and equity firm, and he held senior management posts at Boehringer Ingelheim, Astrazeneca, and Schering.

Bill Bowen has been appointed by Sequenom SVP and general counsel. He will report directly to Chairman and CEO Harry Hixson and will be responsible for the company's legal and patent issues. Bowen was previously with Gen-Probe, where he was SVP and general counsel. Before that he was a business litigation partner at Luce Forward Hamilton & Scripps.

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DuPont, CSHL Extend Plant Biology Research Alliance

DuPont and Cold Spring Harbor Laboratory Extend Collaboration in Cutting-Edge Plant Biology Research for Another Five …

WILMINGTON, Del. & COLD SPRING HARBOR, N.Y.--(BUSINESS WIRE)--

DuPont and Cold Spring Harbor Laboratory (CSHL) today announced the renewal for another five years of a research collaboration that began in 2007. This multi-million dollar collaboration supports cutting-edge plant biology research focused on meeting growing food demands worldwide.

With the worlds population expected to grow by more than 2 billion by 2050, this collaboration will help make possible crucial improvements in plant breeding that will help increase yields from available acreage.

Innovative science and technology are at the core of productivity improvements that will allow us to meet global food security goals of ensuring that people everywhere have access to sufficient and nutritious food that meets their dietary need and food preferences for a healthy life, said DuPont Agricultural Biotechnology Vice President John Bedbrook. We must leverage all the science and technology tools available, including this important collaboration with CSHL. Our collaboration has contributed to and will continue to contribute to increasing our understanding of the basic genetic mechanisms controlling plant growth and development which will contribute to global food security in the coming decades.

CSHLs successful partnership with DuPont Pioneer has fostered strong collaboration between a uniquely aligned group of research and industry scientists, said CSHL President Bruce Stillman. These two groups are leveraging each others strengths to achieve research results that we believe will lead to important improvements in crop yield around the world.

CSHL and Pioneer are investing in discovery research that tackles some of the most fundamental aspects of plant biology. The renewal of the collaboration agreement will continue the expansion of knowledge about the genetic basis of fundamental plant processes controlling growth, development and yield. This collaboration will help facilitate the development of innovative products to meet future global food needs.

As scientists, we get excited about seeing our discoveries translated into real-world applications, said Rob Martienssen, a CSHL professor and Howard Hughes Medical Institute Investigator. It is clear that basic research in these areas has the potential to radically change the face of the agricultural industry.

Founded in 1890, Cold Spring Harbor Laboratory (CSHL) has shaped contemporary biomedical research and education with programs in cancer, neuroscience, plant biology and quantitative biology. CSHL is ranked number one in the world by Thomson Reuters for impact of its research in molecular biology and genetics. The Laboratory has been home to eight Nobel Prize winners. Today, CSHL's multidisciplinary scientific community is more than 360 scientists strong and its Meetings & Courses program hosts more than 12,500 scientists from around the world each year to its Long Island campus and its China center. Tens of thousands more benefit from the research, reviews and ideas published in journals and books distributed internationally by CSHL Press. The Laboratory's education arm also includes a graduate school and programs for undergraduates as well as middle and high school students and teachers. CSHL is a private, not-for-profit institution on the north shore of Long Island. For more information, visit http://www.cshl.edu.

DuPont Pioneer is the worlds leading developer and supplier of advanced plant genetics, providing high-quality seeds to farmers in more than 90 countries. Pioneer provides agronomic support and services to help increase farmer productivity and profitability and strives to develop sustainable agricultural systems for people everywhere. Science with Service Delivering Success.

DuPont (DD) has been bringing world-class science and engineering to the global marketplace in the form of innovative products, materials, and services since 1802. The company believes that by collaborating with customers, governments, NGOs, and thought leaders, we can help find solutions to such global challenges as providing enough healthy food for people everywhere, decreasing dependence on fossil fuels, and protecting life and the environment. For additional information about DuPont and its commitment to inclusive innovation, please visit http://www.dupont.com.

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DuPont and Cold Spring Harbor Laboratory Extend Collaboration in Cutting-Edge Plant Biology Research for Another Five ...

Here Comes the Boom – 2012 Full Movie (Best Comedy) – Video


Here Comes the Boom - 2012 Full Movie (Best Comedy)
Watch Movie: MoviesTree.com A high school biology teacher looks to become a successful mixed-martial arts fighter in an effort to raise money to prevent extra-curricular activities from being axed at his cash-strapped school.From:Marylin BrownViews:0 0ratingsTime:02:10More inFilm Animation

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Here Comes the Boom - 2012 Full Movie (Best Comedy) - Video

She Blinded Me With Science • Billy Bob Kickarilla Cash Jr.


She Blinded Me With Science bull; Billy Bob Kickarilla Cash Jr. Mosh Pit bull; All Guitar Version
"She Blinded Me With Science" Written By Thomas Dolby. Cover Performed By: Billy Bob Kickarilla Cash Jr., Produced By Eric Clayton (Mosh Pit) Heard on 11.1 to 11.3.2012. Video, Victoria #39;s Secret Angels. Lyrics Below In Description. It #39;s poetry in motion She turned her tender eyes to me As deep as any ocean As sweet as any harmony Mmm - but she blinded me with science "She blinded me with science!" And failed me in biology When I #39;m dancing close to her "Blinding me with science - science!" I can smell the chemicals "Blinding me with science - science!" "Science!" "Science!" Mmm - but it #39;s poetry in motion And when she turned her eyes to me As deep as any ocean As sweet as any harmony Mmm - but she blinded me with science And failed me in geometry When she #39;s dancing next to me "Blinding me with science - science!" "Science!" I can hear machinery "Blinding me with science - science!" "Science!" It #39;s poetry in motion And now she #39;s making love to me The spheres #39;re in commotion The elements in harmony She blinded me with science "She blinded me with science!" And hit me with technology "Good heavens Miss Sakamoto - you #39;re beautiful!" I - I don #39;t believe it! There she goes again! She #39;s tidied up, and I can #39;t find anything! All my tubes and wires And careful notes And antiquated notions But! - it #39;s poetry in motion And when she turned her eyes to me As deep as any ocean As sweet as any harmony Mmm - but she blinded me with science "She blinded me with - with science!" She blinded ...From:Billy Bob Kickarilla Cash Jr.Views:97 8ratingsTime:03:35More inMusic

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She Blinded Me With Science • Billy Bob Kickarilla Cash Jr.

Conservation Biology – Wiki Article – Video


Conservation Biology - Wiki Article
Conservation biology is the scientific study of the nature and status of Earth #39;s biodiversity with the aim of protecting species, their habitats, and ecosystems from excessive rates of extinction and... Conservation Biology - Wiki Article - wikiplays.org Original @ http All Information Derived from Wikipedia using Creative Commons License: en.wikipedia.org Author: Diliff Image URL: en.wikipedia.org ( Creative Commons ASA 3.0 ) Author: John James Audubon Image URL: en.wikipedia.org ( This work is in the Public Domain. ) Author: Underwood amp; Underwood Image URL: en.wikipedia.org ( This work is in the Public Domain. ) Author: Unknown Image URL: en.wikipedia.org ( Creative Commons ASA 3.0 ) Author: Jake L. Snaddon, Edgar C. Turner, William A. Foster. (2008) Image URL: en.wikipedia.org ( Creative Commons ASA 3.0 ) Author: Unknown Image URL: en.wikipedia.org ( Creative Commons ASA 3.0 ) Author: Lucag Image URL: en.wikipedia.org ( Creative Commons ASA 3.0 ) Author: Jake L. Snaddon, Edgar C. Turner, William A. Foster. (2008). Image URL: en.wikipedia...From:WikiPlaysViews:0 0ratingsTime:53:29More inEducation

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Conservation Biology - Wiki Article - Video

Russo Academy Intro – Video


Russo Academy Intro
A teacher at Aptos High School named Jacob Russo was inspired by Khan Academy to make his own instructional videos about biology. An articulate student named David Wallace-Goldstein took it upon himself to give Russo a spicy intro for all of his videos. That is what you are about to see. If Russo ever makes money off his videos, David will receive 15% of all proceeds.From:David Wallace-GoldsteinViews:15 1ratingsTime:00:49More inEducation

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Russo Academy Intro - Video

The History of Life on Earth – Crash Course Ecology #1 – Video


The History of Life on Earth - Crash Course Ecology #1
With a solid understanding of biology on the small scale under our belts, it #39;s time for the long view - for the next twelve weeks, we #39;ll be learning how the living things that we #39;ve studied interact with and influence each other and their environments. Life is powerful, and in order to understand how living systems work, you first have to understand how they originated, developed and diversified over the past 4.5 billion years of Earth #39;s history. Hang on to your hats as Hank tells us the epic drama that is the history of life on Earth. Like CrashCourse on Facebook! http://www.facebook.com Follow CrashCourse on Twitter: http://www.twitter.com Table of Contents 1) Archaean Proterozoic Eons 01:53 a) Protobionts 03:54 b) Prokaryotes 04:18 c) Eukaryotes 06:06 2) Phanerozoic Eon 06:42 a) Cambrian Explosion 06:49 b) Ordovician Period 07:36 c) Devonian Period 07:48 d) Carboniferous Period 08:13 e) Permian Period 09:10 References and licenses for this episode can be found in the Google document here: dft.ba crashcourse, biology, ecology, hank green, history, life, human, earth, RNA, genetic material, protobionts, DNA, prokaryote, archaea, archaean, eon, proterozoic, era, period, epoch, fossil record, atmosphere, geologic, time, cyanobacteria, photosynthesis, oxygen revolution, change, environment, eukaryote, endosymbiosis, mitochondria, plastid, algae, cambrian explosion, diversity, animal, evolution, phanerozoic, phyla, ordovician, plant, carboniferous, fossil fuel, system, permian, pangaea ...From:crashcourseViews:9075 1437ratingsTime:13:38More inEducation

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The UCI Arboretum …. conservation of rare and endangered species in California – Video


The UCI Arboretum .... conservation of rare and endangered species in California
http://www.digatree.com The UCI Arboretum is a 12.5-acre botanic garden and HISTORY In the late 1960s, less than a half-decade after the University of California, Irvine became a part of the UC system, the UCI Arboretum was used by the School of Biological Sciences as a plant growing facility for research and teaching purposes. The Arboretum is administered by and is a facility of the School of Biological Sciences. CURRENT Since its early days in the 1970 #39;s, the Arboretum has shifted from its initial focus on South African plants and to include a broad diversity of habitats representative of the California Floristic Province. These include exhibits of Baja California, California Channel Islands including those near Baja California, California Native Grasslands and Wildflowers, Maritime Succulent Scrub, Mojave Desert, Southern Maritime Chaparral, Otay Mesa, and Oak Woodland. FUTURE Like many botanic gardens, the UCI Arboretum is concerned with the conservation of rare and endangered species, and we grow a number of rare, threatened and endangered species both for our displays and genetic conservation as vouchered living material, but also for re-introduction into natural habitats to supplement existing wild stocks. This work is conducted in conjunction with the US Fish and Wildlife Service, the California Native Plant Society, and the Orange County Chapter of the Society for Conservation Biology. RESEARCH As a part of the School of Biological Sciences, the Arboretum hosts a ...From:William HirstViews:0 0ratingsTime:04:32More inPeople Blogs

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The UCI Arboretum .... conservation of rare and endangered species in California - Video

The UCI Arboretum …. Video of rare and endangered Plants California Campus – Video


The UCI Arboretum .... Video of rare and endangered Plants California Campus
http://www.digatree.com The UCI Arboretum is a 12.5-acre botanic garden and research facility located approximately one mile from the University of California, Irvine. The Arboretum features plants and communities from the California Floristic Province and also has an extensive collection of South African species. HISTORY In the late 1960s, less than a half-decade after the University of California, Irvine became a part of the UC system, the UCI Arboretum was used by the School of Biological Sciences as a plant growing facility for research and teaching purposes. The Arboretum is administered by and is a facility of the School of Biological Sciences. CURRENT Since its early days in the 1970 #39;s, the Arboretum has shifted from its initial focus on Channel Islands including those near Baja California, California Native Grasslands and Wildflowers, Maritime Succulent Scrub, Mojave Desert, Southern Maritime Chaparral, Otay Mesa, and Oak Woodland. FUTURE Like many botanic gardens, the UCI Arboretum is concerned with the conservation of rare and endangered species, and we grow a number of rare, threatened and endangered species both for our displays and genetic conservation as vouchered living material, but also for re-introduction into natural habitats to supplement existing wild stocks. This work is conducted in conjunction with the US Fish and Wildlife Service, the California Native Plant Society, and the Orange County Chapter of the Society for Conservation Biology. RESEARCH As a ...From:William HirstViews:0 0ratingsTime:04:32More inPeople Blogs

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The UCI Arboretum .... Video of rare and endangered Plants California Campus - Video

The UCI Arboretum …. Video of rare and endangered species California Campus – Video


The UCI Arboretum .... Video of rare and endangered species California Campus
http://www.digatree.com The UCI HISTORY In the late 1960s, less than a half-decade after the University of California, Irvine became a part of the UC system, the UCI Arboretum was used by the School of Biological Sciences as a plant growing facility for research and teaching purposes. The Arboretum is administered by and is a facility of the School of Biological Sciences. CURRENT Since its early days in the 1970 #39;s, the Arboretum has shifted from its initial focus on South African plants and to include a broad diversity of habitats representative of the California Floristic Province. These include exhibits of Baja California, California Channel Islands including those near Baja California, California Native Grasslands and Wildflowers, Maritime Succulent Scrub, Mojave Desert, Southern Maritime Chaparral, Otay Mesa, and Oak Woodland. FUTURE Like many botanic gardens, the UCI Arboretum is concerned with the conservation of rare and endangered species, and we grow a number of rare, threatened and endangered species both for our displays and genetic conservation as vouchered living material, but also for re-introduction into natural habitats to supplement existing wild stocks. This work is conducted in conjunction with the US Fish and Wildlife Service, the California Native Plant Society, and the Orange County Chapter of the Society for Conservation Biology. RESEARCH As a part of the School of Biological Sciences, the Arboretum hosts a diversity of research projects, including ...From:William HirstViews:0 0ratingsTime:04:24More inPeople Blogs

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The UCI Arboretum .... Video of rare and endangered species California Campus - Video

Man – Video


Man
a non profit fim about men.. offered for film study , psychology,education etc. You can not legislate biology we are what we areFrom:jack shiteViews:0 0ratingsTime:02:39More inFilm Animation

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Man - Video