Precision NanoSystems to Launch the Revolutionary Ignite – BSA bureau

Vancouver BC, Oct 09, 2019 -- Precision NanoSystems (PNI) a global leader of innovative solutions for the discovery, development, and manufacture of nanomedicine based gene and cell therapies, small molecule and protein based drugs is pleased to introduce our newest member of the Nanoassemblr Platform: the IgniteTM available October 15, 2019.

The Ignite embodies everything that made the NanoAssemblr family of instruments the go-to platform for developing new Precision and Gene Therapy medicines for over 100 biopharma companies and featured in over 150 publications. said James Taylor, CEO & Co-Founder PNI. The Ignite brings our latest innovations developed for clinical manufacturing to the bench, and paves the way for new nanomedicine approaches to treat cancer, rare disease and infectious disease.

PNIs proprietary NxGenTM scalable continuous-flow microfluidic technology is at the heart of the NanoAssemblr family, using controlled mixing to reproducibly manufacture the highest quality drug products through a single mixer across scales. Ignite enables rapid benchtop scale development of nanoparticle based RNA, DNA, CRISPR, small molecule and protein therapeutics. Optimized drug products are predictably scaled to advanced preclinical and clinical scale with the NxGen technology on the NanoAssemblr BlazeTM and GMP Systems.

As the leading provider of RNA/DNA drug manufacturing, we designed Ignite with the end in mind developing a robust, scalable process from the earliest stage. Enabling researchers to create transformative medicines at the bench scale, said Euan Ramsay, CCO & Co-Founder PNI.

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Precision NanoSystems to Launch the Revolutionary Ignite - BSA bureau

Religion or Belief Discrimination: Employment Tribunal finds ‘vegetarianism’ is not a belief protected from discrimination – Lexology

An employment tribunal has held that vegetarianism is not protected by discrimination legislation. This is not binding on other tribunals which may come to a different view.

THE FACTS

Mr Conisbee, a vegetarian, was employed by Crossley Farms Ltd for five months before he resigned. He claimed that his vegetarianism is a belief and that he had suffered discrimination because of this belief. At a preliminary hearing, an employment tribunal considered whether vegetarianism is protected by discrimination legislation.

In a previous case, the EAT gave the following guidance on what constitutes a belief for the purposes of being protected as a religious or philosophical belief:

Considering this guidance, the tribunal accepted that Mr Conisbee had a genuine belief in his vegetarianism and that the practice of vegetarianism is worthy of respect in a democratic society and not incompatible with human dignity and the fundamental rights of others. However, it considered that:

Accordingly, the tribunal held that vegetarianism is not protected as a belief. The tribunal distinguished vegetarianism from veganism, and the judge in this case would likely have found veganism constitutes a belief, capable of protection from discrimination.

WHAT DOES THIS MEAN FOR EMPLOYERS?

As this is a tribunal decision, it is not binding on other tribunals. The case demonstrates how tribunals might treat future claims by vegetarians who claim they should be protected from discrimination. However, it is also possible that another judge would find that vegetarianism is a protected "belief", not least because climate change has already been found to be a protected belief and some vegetarians may eat as they do because of the impact of cattle farming on the environment among other reasons. This is certainly an area that is likely to be revisited over the coming years.

Conisbee v Crossley Farms Ltd and other ET/3335357/2018

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Religion or Belief Discrimination: Employment Tribunal finds 'vegetarianism' is not a belief protected from discrimination - Lexology

An Increase in Variety of Vegetarian Food could Tempt Carnivores to Stay Away From Meat. – DailyHealthTalks

With Climate Change on individuals minds and livestock farming in trouble for greenhouse gas emission, many individuals see vegetarianism as a positive step. A research advises that offering a greater vegetarian selection should be a way to lure meat eaters into selecting more veggie meals.

Livestock farming gets a bad rap for its contribution to greenhouse gases, which trap heat and contribute to global warming. In the United States, agriculture contributes 9% of gas emissions to the atmosphere, much of which is down to livestock. By passing gas, ruminants, such as cattle and sheep, pass methane into the atmosphere. Methane is 25 times more powerful at trapping heat than carbon dioxide and concentration have more than doubled in the last 200 years.

So, lowering methane levels in the atmosphere could have and important positive impact on the environment, which is why vegetarianism seems like a viable solution.

A new research from the University of Cambridge in the United Kingdom shows that the solution as adding more vegetarian options to menus. The paper appears in the journal Proceedings of the National Academy of Sciences.

The research observed at the sales information over 94,000 meals in three unnamed Cambridge College cafeterias over a year. It discovered that by doubling vegetarian choice to 2 out of 4 of the meal options available, the sales of vegetarian meals increased by 40.8% to 78.8%.

This research is significant because high eat diets are incompatible with a safe climate, so we need to find effective simple, non-controversial approaches to get us all to eat more plant based food.

Meat eaters might also order veggie options

The Cambridge study members discovered that the biggest meat eaters- those who had consistently chosen fish or meat before the second vegetarian option became available- were the one who opted for a vegetarian meal in the largest numbers.

Not only did that but having a vegetarian lunch not make it any more possible that the traditional meat eaters would compensate by having a meaty dinner.

The research which observed at diners daily meal choices through payments made on university cards ran through two canteens. The canteens varied their range from no vegetarian dishes at all to days when 75% of options were vegetarian.

A third canteen offered lunchtime menus that shifted every 2 weeks from one veggie option to two. Investigators concluded that upping the proportion of vegetarian meals had the most important effect on those who ordinarily chose more meat.

The response was striking, says Garnett. It seems obvious in hindsight, and a number of commentators have asked, Why is this science? Isnt this obvious? I would say yes and no. If we had discovered no effect which could also seem obvious.

She continues, I find it fascinating that by responding, people are implicitly acknowledging that our food environments can have a strong influence on what we eat and other health behaviors.

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An Increase in Variety of Vegetarian Food could Tempt Carnivores to Stay Away From Meat. - DailyHealthTalks

Healthy Living: Get back to you now that back to school is over – Vail Daily News

Editors note: The Healthy Living column provides exercise and diet tips from the Grand Hyatt Vail to help readers live their healthiest lives.

As many parents know, the back to school season can be a hectic time of year.

Between making lunches, running to sports practices or rehearsals and juggling work, it can be hard for parents to relax.

But now that its October and kids are getting back in the swing of things, now is a good time to get back to you.

Too often, people get in the mindset that a workout needs to be an hour long to count, but that simply is not the case.

A workout can be any length of time. After all, moving for a short period of time is better than not working out at all.

A 20-minute workout can yield great results and fits into a busy schedule.

To maximize a shorter workout, try a higher-intensity interval workout that pushes exertion higher, faster. Shorter and more intense bursts of exercise increase heart rate and cause the muscles to start burning more quickly.

A few other tips for maximizing a high-intensity interval training workout include a short warmup, keeping intervals to 2 minutes or less and not overdoing it, especially when starting a new routine.

Group fitness classes are another great way to get moving.

Most gyms offer midday classes throughout the week including spin, yoga, barre and more. Check out your gyms class schedule for more information. Aria Athletic Club offers noon classes on various days throughout the week, with rotating classes and new ones added each month.

Finding a routine is key, and sticking to it is even more important.

Having a method and time of day to work out that excites individuals will make it easier to stick with the routine.

For those struggling to get a new routine started, be sure to set manageable goals.

New runners shouldnt make a marathon their first goal because theyll get burned out easily maybe start by training for a 5K instead. Once you smash that personal record or lift that goal weight, find another goal to add on and keep building from there.

This time of the year is also great to implement healthy eating habits for the entire family.

Starting small, focus on beginning the day with a healthy breakfast, and including nutrient-rich snacks with fiber and protein in lunches.

For breakfast, try adding a fried or hard-boiled egg to your go-to avocado toast.

Switch from savory to sweet with a berry and yogurt parfait, or even prepare ahead and make a quiche. Mixed nuts and apple slices with peanut butter and even a little bit of dark chocolate are great snack options for parents and children alike.

As with starting a new exercise program, create small goals and then build from there to include healthy food options in each meal.

Emily Dornan is the club director at Aria Athletic Club at Grand Hyatt Vail. For more information on implementing healthy exercise and food habits, you can reach her at 970-479-5949 or edornan@ariaclub.com.

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Healthy Living: Get back to you now that back to school is over - Vail Daily News

Center celebrates 6 years of healthy living – Tyler Morning Telegraph

The Center for Health Living welcomed its first client on Oct. 16, 2013.

The old fire building on Texas Highway 155 South in Tyler was established to continue providing a lifesaving function to the citizens of Tyler through the partnership between the city of Tyler and Northeast Texas Public Health District (NET Health) to provide chronic disease prevention services to underserved and uninsured communities in Tyler and across East Texas.

As a unique fixture within the St. Louis community of Tyler, The Center for Healthy Living (aka The Center) is the only local community health center in the area and the first of its kind to be staffed by four certified community health workers (CHWs) and a certified health education specialist. The majority of our clients who have been seen and screened at The Center are uninsured and unemployed loved ones, friends and family in your neighborhood, coworkers and customers of your company.

The staff at The Center offers free chronic disease prevention education and resources Monday through Friday. Throughout our six years of operation, The Center has provided diabetes prevention and diabetes self-management education to mroe than 200 clients and health screening services to more than 2,000 clients. Within the past year, more than 600 uninsured clients were scheduled for free pap smears and mammograms in an effort to counteract the rates of breast cancer and colon cancer in the Tyler area, which are both higher than the state and national averages.

The Center offers a home blood pressure monitor project to people identified as having undiagnosed or uncontrolled high blood pressure. Participants are given a free blood pressure monitor to check their blood pressure daily for 16 weeks, so that our CHWs can call each participant to obtain numbers and provide additional education and assistance. Average blood pressure before the project was 161/92 mmHg. After the completion of the program, blood pressure among the participants decreased at an average of 18 systolic points and 9.5 diastolic points, and persons enrolled in our 16-week project maintain an 86% completion rate.

The Center has also become the hub for a community clinical linkage project called CommUNITY Cares. Our CHWs electronically connect uninsured individuals to a primary care home and to the social services agencies best suited to address the persons health needs. Through a network of clinical and community partnerships, the CommUNITY Cares project addresses insufficient access to primary health care services, removes the high costs due to potentially preventable hospitalizations and minimizes inappropriate emergency department use by individuals seeking health care in an emergency room. Referrals to The Center come from Tyler hospital ERs and social service agencies. More than 125 uninsured have successfully been enrolled in a primary health care home.

Since February 2017, The Center maintains annual accreditation through the American Association of Diabetes Educators for diabetes services. The Center is the only National Diabetes Prevention Program site in Northeast Texas recognized by the Centers for Disease Control and Prevention. Two members of our staff are lifestyle coaches who provide free classes on how to prevent diabetes, to safely lose weight and to learn how to easily enjoy a healthy lifestyle.

This designation is reserved only for programs that have effectively delivered a quality, evidence-based program that meets all of the standards for CDC recognition. The sustained success of our lifestyle change program makes an invaluable contribution to the prevention of type 2 diabetes, both in our Northeast Texas region but also nationally. According to data collected by the CDC, over 86% of health care spending in the U.S. is for chronic disease, and The Center for Healthy Living continues to minimize these costs within the East Texas area.

Joy Johnson is NET Health assistant director of community outreach. NET Health will continue to talk about Your NET Health. This feature will focus on a variety of health issues that hold importance to your community. Let us know if you have questions about our article, or if you have a topic or topics that you want us to cover, by sending us an email at ContactUs@netphd.org.

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Center celebrates 6 years of healthy living - Tyler Morning Telegraph

In the cause of healthy living – Barbados Today

Students and staff of The St Michael School took to the streets today to advocate for Childhood Obesity Prevention.

Wearing games clothes, sneakers and holding placards in hand, over 800 students walked through the environs of the Martindales Road, St Michael institution, to bring awareness to childhood obesity, an issue that has been the centre of national discussion in recent years due to discouraging statistics.

Principal Yvette Mayers said that while today marked World Obesity Day, St Michael was one of the model schools appointed by the Heart and Stroke Foundation to work in the campaign against obesity.

We felt that we should go through the community to share some information on health and to make a statement. The first time we had a walk for health in 2016, we had only about half the school participate. And we had so much fun on the road that those children came back and shared their experiences with others.

So this morning, only about 30 persons said they dont want to walk. But our students are always motivated to get involved with what is going on in the school. So I am very pleased with the response from our students, Mayers said.

The principal noted that the schools management has been making several necessary decisions to motivate and encourage students to live healthier lifestyles. She said since the beginning of the 2019/2020 school year, St Michael has not been selling carbonated beverages to students.

We have taken the plunge to take the carbonated beverages out of the school. Our focus since 2015 has been on water. We are encouraging our students to use more water and so a large majority of our students are accustomed to sipping water throughout the day from the time they enter the school. There are some students that the only thing you see them drinking is water, Mayers said.

Throughout the day, the students participated in healthy activities and exercise sessions, including Zumba. There was also a health exhibition where the students were encouraged to learn more about healthy foods and products, and also have various health checks. (AH)

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In the cause of healthy living - Barbados Today

Arc Healthy Living column: Norwich boy sees the benefits of helping disabled – Norwich Bulletin

When Max turned 12 last summer, he invited five friends to sleep over at his house and celebrate his birthday. Presents? Max asked his friends not to give him presents. Instead, Max and his mother, Sarah, called The Arc Eastern Connecticut and learned that puzzles, games and art supplies are always in demand.

So, Max asked his friends to bring to the party games like Sorry, Trouble and Rubiks Race; also, glue, Play-Doh, tape and other craft materials. Then, on a breezy September afternoon, Max and Sarah delivered the gifts that werent Maxs to The Arc ECT on Sachem Street in Norwich.

A student at Integrated Day and Charter School (IDCS), Max runs cross country and track. I just like running! He also enjoys sprinting and is working on his ability to compete long-distance. Another reason he chose IDCS is the music and arts programming. I like art, and I want to learn to play the guitar. His dad, Craig, used to play guitar in a band. Max also has a turntable. I like mixing songs.

Max had already decided to donate his birthday presents to people with special needs when his mom, a special education teacher at Norwich Free Academy, suggested The Arc. The year prior, hed chosen St. Vincent de Paul Place.

Max ticks off statistics. Employment rates for people with Intellectual and Developmental Disabilities (IDD) have been flat for 20 years. Their unemployment rate is 80%! he says.

People with disabilities, Max says, deserve the same chances as everyone else.

Max lives in Norwich with his mom, dad, and sisters Sadie, 14, and Abby, 18. Given a choice, hed rather be 16. Although Max does know someone with autism and had a friend back in first grade with a heart condition, his passion for inclusion is more heartfelt than personal.

Max notices things, and he doesnt like what he sees when adults speak to children with IDD.

They kind of talk to them like theyre in first or second grade when theyre really, like, in sixth grade, Max says.

Max wants everybody to understand just one thing: A person with disabilities, theyre just a normal person.

Kathleen Stauffer is chief executive officer of The Arc Eastern Connecticut. For information on The Arc, go to http://www.TheArcECT.org. For more articles by this author visit http://www.kathleenstauffer.com

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Arc Healthy Living column: Norwich boy sees the benefits of helping disabled - Norwich Bulletin

Nanomedicine Market: Industry Growth, Competitive Analysis, Future Prospects and Forecast 2026 – Chronicle Voice

The Nanomedicine Market is projected to grow at a rate of 12.6 percent by 2026, to reach USD 343.8 billion in 2026 from USD 132.8 billion in 2018.

The latest report, Nanomedicine market enables stakeholders to gain insights into their potential consumers to construct more effective marketing strategies for the forecast period, 2019 to 2026. Most importantly, the document empowers business owners to seek information about potential consumers and where they can find them. Apart from this, the literature sheds light on how major vendors operating in the Nanomedicine market are making the best use of their marketing campaigns. With an exclusive coverage of the top vendors, the study enables business owners to know more about the local market and locate potential consumers.

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Besides, with real-time data available, the research identifies vital information about buyers such as their age, gender, spending power and end-use. This data can also be used to explore additional information about loyal consumers. The recent report on Nanomedicine market lets you understand what the recent market looks like. It helps product owners get a quick view of the potential buyers who is right around the business so that they can meet and better appeal their requirements. In addition, the study gets accurate statistics that can be used to start or expand the business, including the desired geography.

Companies considered and profiled in this market study

Arrowhead Pharmaceuticals, Inc., Nanospectra Biosciences, Inc., AMAG Pharmaceuticals, Bio-Gate AG, Celgene and Johnson & Johnson

Segments covered in the report:

This report forecasts volume and revenue growth at a global, regional & country level, and provides an analysis on the industry trends in each of the sub-segments from 2018 to 2025. For the purpose of this study, Reports and Data have segmented the global Nanomedicine Market on the basis of products, drug delivery system, application and region:

Products (Revenue, USD Billion; 2018-2026)

Drug Delivery System (Revenue, USD Billion; 2018-2026)

Application Outlook (Revenue, USD Billion; 2018-2026)

Regional Outlook (Revenue, USD Billion; 2018-2026)

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The report not only empowers companies and individuals to understand the key characteristics of the target market but also the communication preferences. The audience can get the estimated size according to the number of sales in a specific region. By offering access to insights about the profit margin the study aims at improving the communication between the companies and potential customers. Armed with all required information on the recent development in the competitive landscape such as a joint venture, collaboration, acquisition and merger and product launch the study enables business owners to build a strong profile of their best buyers.

The market intelligence report on the Nanomedicine market further investigates the demographic as well as behavioural characteristics. Those planning on creating an effective marketing and sales campaign around potential segments are likely to benefit from the research. The extensive document includes a breakdown of all the key geographic characteristics, substitutes, lifestyle categories and marketing communication. Research provides companies and individuals access to data on customer requirements and off-the-shelf information on their spending capacity

The research provides answers to the following key questions:

To identify the key trends in the industry, click on the link below: https://www.reportsanddata.com/report-detail/nanomedicine-market

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Nanomedicine Market: Industry Growth, Competitive Analysis, Future Prospects and Forecast 2026 - Chronicle Voice

Global Injectable Nanomedicines Market Projected to Reach USD 833.9 Million by the End of 2025 – MENAFN.COM

(MENAFN - GetNews) Rising adoption of minimally invasive treatments for chronic disorders across the globe will propel the growth of injectable nanomedicines market during the forecast period

Theglobalinjectable nanomedicines market touched USD 479.6 million in 2017, and is expected to reach USD 833.9 million by 2025, growing at a CAGR of 7.3% during 20182025.

Source: GMI Research

Major Factors driving the market growth are: Growing incidence of chronic diseases like cancer, cardiovascular diseases, neurological disorders Increasing research & development activities and clinical trials Rising demand and adoption of minimally invasive treatments Rising government and private funding Increasing geriatric population

Growing demand for minimal invasive treatments is driving the Injectable Nanomedicines market. Introduction of innovative and advanced nanotechnology and nanomedicines, especially in the emerging markets with the help of government and private funding would spur the growth of market for the injectable nanomedicines during the forecast period.

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A paradigm shifts from traditional therapeutics to novel therapeutics using nanomedicines is propelling the overall market as nanomedicines have higher payload capacity, prolonged blood circulation times, reduced toxicity and improved anti-tumour efficacy. Moreover, the application of injectable nanomedicines for some widespread chronic diseases like migraine and depression is also aiding market growth. The use of injectable nanomedicines are found to be efficient, lasting and easy treatment of many chronic cardiovascular and neurological disorders.

Growing incidence rate due to aging demographic patterns and the extension of health insurance coverage in a developing region will support the market growth. Advancements in cancer drug delivery and personalized cancer treatments, effective and safe treatment of medically refractory movement disorders and the need for fast and efficient cardiovascular systems will primarily drive the global injectable nanomedicine market.

'The rising pool of patients of chronic diseases and the need for a fast, efficient and long-lasting treatment with minimal invasion procedures will drive the injectable nanomedicines market.-GMI Research

Based on geography, North America held the largest market share in 2017 due to the significantly high rate of incidence of cancer as well as cardiovascular diseases in the region. Currently, the region has a growing demand for rapid research & development of novel nanomedicine in order to address unmet medical needs. Furthermore, favourable reimbursement policies and increasingly growing partnerships between leading enterprises and nanomedicine start-ups is also expected to create growth opportunities. Europe is the second largest market in 2017 and is promising market due to developed healthcare system and rising adoption of nanomedicine in oncology sector. Asia-Pacific is expected to show promising growth in global injectable nanomedicines during 2018-2025 due to the increasing government and private funding for health care infrastructure along with the rising incidence of neurological disorders. Moreover, increasing adoption of nanomedicine for the treatment of cancer, diabetes, cardiovascular diseases and some infectious disease in the Asia-Pacific region would also contribute significantly to the market growth for injectable nanomedicines in the region.

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Based on geography, North America held the largest market share in 2017 due to the significantly high rate of incidence of cancer as well as cardiovascular diseases in the region. Currently, the region has a growing demand for rapid research & development of novel nanomedicine in order to address unmet medical needs. Furthermore, favourable reimbursement policies and increasingly growing partnerships between leading enterprises and nanomedicine start-ups is also expected to create growth opportunities. Europe is the second largest market in 2017 and is promising market due to developed healthcare system and rising adoption of nanomedicine in oncology sector. Asia-Pacific is expected to show promising growth in global injectable nanomedicines during 2018-2025 due to the increasing government and private funding for health care infrastructure along with the rising incidence of neurological disorders. Moreover, increasing adoption of nanomedicine for the treatment of cancer, diabetes, cardiovascular diseases and some infectious disease in the Asia-Pacific region would also contribute significantly to the market growth for injectable nanomedicines in the region.

Key takeaways/key essentials: In 2017, the cancer treatment held the major share for the injectable nanomedicines market followed by the cardiovascular diseases segment. High demand and adoption rate for minimally invasive treatments in the recent past. Extended research and development activities are taking place using the injectable nanomedicines regarding the concept of targeted drug delivery system.

Some of the key players operating in the global market for injectable nanomedicines include Merck & Co., Inc., Lupin, Pacira Pharmaceuticals Inc., Celgene Pharmaceutical Co. Ltd., Amgen, Inc., Janssen Biotech Inc., Pfizer Inc., Hoffmann-La Roche Ltd., Teva Pharmaceutical Industries Ltd., Bausch & Lomb Inc. among others.

The globalinjectable nanomedicines market has been segmented based on product type, indication type and key geographies. Based on the product type, global injectable nanomedicines market has been segmented into liposomes, micelles, nanocrystals and others. Based on indication type, the market has been segmented into cancers, central nervous system diseases, cardiovascular diseases, inflammatory diseases and others.

The research report ' global injectable nanomedicines market provides in-depth analysis of injectable nanomedicines market, globally, based on product type, indication and major geographies for the forecast period from 2018 to 2025. The report highlights the major market drivers fuelling the growth as well as challenges faced by the market participants. The research report provides market size and forecast for injectable nanomedicines market. The report also analyses the competitive landscape, major players and their strategies in 2018. The competitive landscape section of the report captures and highlights the recent developments in the market.

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About GMI Research

GMI Research is a market research and consulting firm which provides research-based solutions to business executives and investment professionals so that they can make right business & investment decisions faster based on real facts. We help business leaders through independent fact-based insight, ensuring their business achieve success by beating the competition.

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Company Name: GMI RESEARCHContact Person: Media RelationsPhone: +353 1 442 8820Address:Level 1, The Chase Carmanhall Road, Sandyford Industrial EstateCity: DublinState: DublinCountry: IrelandWebsite: http://www.gmiresearch.com

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Global Injectable Nanomedicines Market Projected to Reach USD 833.9 Million by the End of 2025 - MENAFN.COM

Nanomaterials in Theranostics Market by Segmentation: Based on Product Application and Region 2016 2024 – Space Market Research

Global Nanomaterials in Theranostics Market: Overview

The application of theranostics in nanomedicine is a fast emerging paradigm, which involves the use of nanoparticles or nanoscale materials for a variety of diagnostic, imaging, and therapeutic applications. Recent research efforts have been increasingly focused on designing functional nanomaterials for non-invasive imaging of diseases, including bioimaging and biosensing, advanced biomarkers, and targeted delivery of therapeutic drugs. Efforts are also underway for developing highly biocompatible nanoplatforms for various theranostic nanomedicine applications.

Several nanomaterials in theranostics have proven promising for the treatment of chronic and fatal diseases such as cancer, AIDS, and various types of cardiovascular diseases. Adequate surface modifications are being made in a variety of polymeric and inorganic nanoparticles to enhance their conjugation with biomolecules and their interactions with target tissues. As a result, the market is witnessing the development of various classes of nanoscale particles with reduced cytotoxicity and advanced therapeutic applications, improving the quality of life for patients.

The report offers in-depth insights into the key market dynamics, current trends, and recent technological advances in nanomaterials, emerging theranostics applications, lucrative avenues, and competitive dynamics. The research study takes a closer look at several cross-disciplinary researches in drug discovery and highlights major developments in nanomaterials by leading players for expanding theranostics applications.

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Global Nanomaterials in Theranostics Market: Trends and Opportunities

The rising incidence of chronic and life-threatening diseases, coupled with the need for improving disease detection, and the demand for advanced chemotherapeutic treatments are the key factors propelling the market. The growing potential of clinically translatable nanomaterials in the areas of biological imaging and therapy is anticipated to boost the market. Continuous researches in improving the biocompatibility of a range of nanoparticles, mainly through appropriate surface modification, has fuelled the demand for nanomaterials in theranostics.

In addition, increasing applications of nanoparticles for effective target-specific drug delivery has stimulated their applications in hyperthermia-based cancer treatments, thereby bolstering the demand for nanomaterials in theranostics. Some of the most common classes of nanoparticles used in theranostic applications are gold nanoparticles, mesoporous silica nanoparticles, quantum dots, and nanocrystals. However, lack of favorable regulatory framework, stringent approval requirements, and spiraling developmental costs are some of the key factors likely to hinder the nanomaterials in theranostics market to an extent. Nevertheless, recent partnerships and collaborations between several pharmaceutical and medical devices companies and substantial investments of biotech companies in nanoparticles are expected to unlock abundant opportunities for market players over the forecast period. Furthermore, the application of carbon-based nanoparticles for making a wide range of drug delivery systems is expected to open up lucrative avenues in the coming years.

Global Nanomaterials in Theranostics Market: Regional Outlook

North America is one of the major markets for nanomaterials in theranostics. In the U.S., the theranostic witnesses wide applications in biosensing, bioimaging, and targeted drug delivery. Recent translational researches in the region have expanded the potential of theranostic nanomedicine for a variety of diseases, thereby boosting the nanomaterials in theranostics market. In addition, a robust awareness among patients and clinicians in the efficacy of nanomaterials in theranostics, and aggressive efforts by manufacturers to market their products are expected to catalyze growth. Europe is another prominent market for the demand for nanomaterials in theranostics. The substantial growth of this regional market can be attributed to growing number of product approvals and vast unmet market needs.

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Asia Pacific is expected to show vast opportunities for numerous manufacturers and vendors. This is attributed to increased focus on R&D activities in nanoparticles, cheap procurement of raw materials, and a rapidly rising patient population pool.

Companies mentioned in the report

Companies vying for a sustained share in the nanomaterials in theranostics market include Abalonyx, Nanomat, Inc. Affymetrix, Aldlab Nanotech, Berkeley Advanced Biomaterials, Inc., ACS Materials, AMAG Pharmaceuticals, Inc., Applied Graphene Materials plc, A.P. Pharma, Inc., Monogram Biosciences Inc., Nanocarrier Co. Ltd., Liquidia Technologies, Inc., and Advanced Proteome.

Leading players are resorting to acquisitions and collaborations to consolidate their positions across major regions.

Major regions analyzed under this research report are: North America Europe Asia Pacific Rest of the World (RoW)

This report gives you access to decisive data such as: Market growth drivers Factors limiting market growth Current market trends Market structure Market projections for the coming years

Key highlights of this report Overview of key market forces propelling and restraining market growth Up-to-date analyses of market trends and technological improvements Pin-point analyses of market competition dynamics to offer you a competitive edge An analysis of strategies of major competitors An array of graphics and SWOT analysis of major industry segments Detailed analyses of industry trends A well-defined technological growth map with an impact-analysis Offers a clear understanding of the competitive landscape and key product segments

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Nanomaterials in Theranostics Market by Segmentation: Based on Product Application and Region 2016 2024 - Space Market Research

The Best Cities For Vegans and Vegetarians in 2019 – Forbes

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Growing up, someone was always cooking meat in my household. My grandmother was an amazing cook and soulfully prepared fried chicken, smothered pork chops, chilis and stews right up until she died last year. She was even known to whip up pigs snout, cows tongue and chicken feet on special occasions, but Id always make myself scarce on those days.

It never occurred to me that, one day, Id be preparing food with vegetarian children in mind. Ive got six kids ranging from 26 down to 3-year-old twins and four of them will not touch meat. As their mother, I can assure you that from the moment they could digest food, they knew they didnt want animal protein.

So, when the holidays roll around, Im quite busy preparing different dishes for the keto eaters in our family, the gluten-free crowd and my league of vegetarians. When we go on vacation, we even try to pick destinations that will accommodate our varied dietary needs. Recently weve been looking to relocate, which is why WalletHubs 2019 Best Cities for Vegans and Vegetarians immediately caught my eye.

The Method

There are roughly 10 million vegan and vegetarian adults in the United States. Depending on where you live, though, finding meatless options at local grocery stores and restaurants can be difficult. Thats why WalletHub set out to find the 100 largest cities with the best and most affordable plant-based options across the country.

The team looked at 17 key indicators including the cost of groceries, number of salad shops and share of restaurants serving meat-free dishes. For the full findings and description of the methodology used to compile the list, see the full article.

The Top 10

While there was a time when vegetarianism was closely associated with a California lifestyle, looking at the top 10 cities on WalletHubs list, its clear that people across the country are choosing a meatless diet. Lets take a look:

These cities are spread all across the country, which is not surprising considering acceptance of veganism and vegetarianism has grown the number of vegans increased by 600% between 2014 and 2017.

Plant-Based Options Are Growing

The options for plant-based eaters are growing every single day. Just look at how many meatless meals are now available at fast food restaurants! Who would have ever thought that Burger King would sell an Impossible Whopper, which contains zero beef? Yet, chains such as Carls Jr. and White Castle are carrying burgers that vegetarians can actually enjoy.

Gone are the days where theyd be forced into ordering nothing more than a salad at sit-down restaurants. Today its pretty common to find a whole section of meatless appetizers and entrees on menus. The offerings are becoming bolder and more creative too, a trend for which vegans and vegetarians nationwide are undoubtedly thankful!

While plant-based options are growing across the country, its great to have a list of cities that are particularly friendly for vegans and vegetarians. Its so much easier to live a fulfilled, happy life in a community where you feel supported. Not happy with whats available in your area? One of these cities might just be for you!

Read more:
The Best Cities For Vegans and Vegetarians in 2019 - Forbes

US cities with the best choices for vegans and vegetarians – Lonely Planet Travel News

More and more travellers are turning to vegetarianism 10'000 Hours

As anyone who has tried it can attest, vegan and vegetarian cuisine can very often be delicious, hearty, healthy and satisfying. And while it has gotten easier to find good veggie options while on the move, sometimes it can be tricky. With that in mind, a new study has unveiled the top cities in the US for vegan and vegetarian food, meaning you can start brainstorming your next culinary adventure.

According to a 2019 Harris Poll commissioned by the Vegetarian Resource Group, approximately 10 million adults in the United States are vegan or vegetarian. Released by WalletHub, the new study compared the 100 largest American cities across 17 different categories, including average meal cost, the price of groceries for vegetarians, the number of restaurants serving meatless options, salad shops per capita, number of community gardens, frequency of juice and smoothie bars and fruit and vegetable consumption.

Scooping the top spot in the whole study was Portland, Oregon, a city that has enjoyed a long standing reputation as an alternative, multicultural and trendy hotspot not only vegan and vegetarian cuisine, but food and culture in general. The top ten was completed by Los Angeles, Orlando, Seattle, Austin, Atlanta, New York, San Francisco, San Diego and Tampa, while Scottsdale, Anaheim, Chicago, Madison, Milwaukee, Washington, Las Vegas, Pittsburgh, Houston and Charlotte were also named amongst the best in the country. Scottsdale, Arizona was shown to have the highest share of restaurants serving vegetarian options at 20.14%, which is 12.5 times higher than Laredo, Texas, the city with the lowest at just 1.61%.

Scottsdale also claimed the title of city with the highest share of restaurants serving vegan options, while Newark, New Jersey is the city with the least amount of restaurants catering to vegans. San Francisco has the most community-supported agriculture programmes per square root of population, just over 20 times more than San Antonia, the city with the fewest. And if youre on the hunt for a good salad shop, look no further than New York, which was shown to have the most per square root of population, while Laredo, Texas has the fewest. Cities in the bottom ten were El Paso, San Bernardino, Greensboro, North Las Vegas, Baton Rouge, Henderson, Winston-Salem, Stockton, Tulsa, Memphis and Laredo.

The full findings are available on the official WalletHub website.

See more here:
US cities with the best choices for vegans and vegetarians - Lonely Planet Travel News

Where do you find amazing vegan Vietnamese food in the Bay Area? Look for this Buddhist temple in East Palo Alto – San Francisco Chronicle

During the month of October, Soleil Ho is only reviewing vegetarian restaurants. Have a suggestion? Let us know: food@sfchronicle.com

When driving through East Palo Alto, its easy to miss Chua Giac Minh, a buttercream-colored pagoda tucked into a residential street behind Ikea. The Vietnamese Buddhist temple, the oldest in Northern California, isnt much taller than the nearby houses. I showed up one Sunday based on a reader tip; until I spied the buildings curved eaves, I was worried I had wasted an afternoon on a plant-based goose chase.

I was searching for Vietnamese temple cuisine, a Mahayana Buddhist tradition that has refined its own plant-based versions of fish sauce, chicken wings, pork belly and seafood over the course of 2,000 years. As someone who didnt grow up Buddhist, I was curious about how Vietnamese food, a cuisine that is notorious for fish sauce and beefy banquets, would translate to a vegan paradigm. In the Catholic church wherein I was raised, post-service meals appeared on festival days: trays of vermillion- and green-tinted sticky rice, glazed barbecue chicken wings and spring rolls filled with pork and canned crab meat.

At Chua Giac Minh, the offerings proved to be an absolute treasure trove of delights, a must-visit for vegans, Vietnamese food lovers and anyone in between. The audience for Chua Giac Minhs meals is definitely the temples adherents, but random people who just want to eat lunch (like your intrepid food critic) are welcome to join in. The recipes are generated by the volunteers as well as the nuns, and many of the ingredients are sourced locally or grown on-site.

I have to admit, though: Religion kind of scares me. As I wandered into the temple kitchen with the tentativeness of a child looking for a midnight snack, a follower waved me down. I cringed, expecting to be asked what I was doing there or told what I was doing wrong.

But she smiled and asked if I needed help.

That question carries a lot of weight in a house of worship, but I nodded and she showed me the ropes. When I sat down with my food, she came over to talk to me. She told me that when she first visited the temple with a friend years ago, she was habitually spending her evenings partying at bars and just floating along, living for herself. But she was welcomed despite being a complete stranger and has been a loyal follower and volunteer ever since.

Until my visits to this temple, I hadnt entered a religious space for years and was a little worried Id burst into flames as soon as I crossed the threshold. But what I didnt realize going in was just how drastically my attitude toward veganism, weighted down and muddled by press releases about the Impossible Burger and pseudoscientific influencer rhetoric, would shift.

Here, everything the food, the sense of community is rooted in a culture of care.

In efforts to welcome guests of all persuasions, Buddhist missionaries and clergy have historically crafted foods that would appeal to the masses. At this temple, that tendency comes through clearly in dishes like the soy-based mock fish, which cleverly uses sheets of nori to imitate the skin of a fish filet. Strips of tofu skin, steamed together in the nori, are dead ringers for the fibrous flesh of a tilapia. The texture was, in a word, stunning.

763 Donohoe St., East Palo Alto

Hours: 10 a.m.-3 p.m. Sundays.

Accessibility: No steps to dining area, but entry to the temples upper level requires climbing a flight of stairs. Gendered multistall restrooms that run narrow.

Noise level: All outdoors in the courtyard; quiet, but more raucous on major holy days.

Meal for two, sans drinks: $15-$20. Donation based; cash only.

What to order: Braised tofu skin roll, spring rolls, braised fish, bao. For dessert, be sure to grab che bap ($1.50), a thick corn-and-tapioca pudding covered with a layer of coconut cream. Its sweet in the way a perfect can of corn is, with the lusciousness of a creamy corn potage.

Plant-based options: Everything is vegan except for the yogurt.

Drinks: Fresh-pressed sugar cane juice available; sometimes with additional fresh fruit juice.

Transportation: On the 281 and 296 SamTrans lines. Private parking available.

Best practices: Youre welcome to eat lunch with the temples worshipers at the communal tables. Carry-out is also an option, but go early in the day before they start running out of items.

The minced tofu and mung bean noodle chicken ($3 for 5, baked or fried), hefty and moist like thigh pieces, came complete with lemongrass bones and tofu skin. The imitations were clearly imitations, less like uncanny meat changelings and more like the Dionne Warwick impersonator at your friendly neighborhood drag bar.

For many Buddhists, the practice of eschewing meat, and sometimes alliums like onions and garlic, is an integral part of their religious lives. Onions and garlic are considered by devout followers as aphrodisiacs, making them inappropriate for temple food. Most lay followers are vegetarian on holy days, while the diet is a daily requirement for clergy. (Though I came into this with the hope that vegan Vietnamese food would be excellent in its own right, it was the exclusion of onions and garlic that really impressed. Somehow, I didnt miss them.)

While certain sects vary in their rationale, the general practice of vegetarianism in Buddhism resonates with secular environmentalism: Both are about recognizing the myriad ways our actions reverberate outside of private acts and using that knowledge to minimize harm. For them, what we eat has an inherent philosophical significance beyond its plain function. While some people may take issue with the idea of infusing food with so much meaning, I didnt pick up on much anxiety or stress while eating at the temple with its followers. They were all in this together, and it just felt normal. To that end, Chua Giac Minh also serves food to homeless people in Redwood City once a month, though the volunteers tailor the menu to their audience with a broader range of foods like spaghetti, fajitas and cookies.

Heres what it looks like in the moment: Every Sunday, a team of nuns and volunteers at Chua Giac Minh cooks food underneath the elevated temple, mainly for community members who are attending the weekly morning service. When the service ends, usually at 12:30 p.m., the temple offers each person a free bowl of noodles, vegan takes on classic soups like bun bo Hue or bun rieu. The latter is a particularly inspired rendition, and I realized how well it took to a vegan preparation: fluffy clumps of tofu absorbed the juicy sweetness of the tomato-scented broth and took on the same delicate texture of the eggy meatballs in the omnivorous version. Annatto oil and thin shreds of shiso and rau ram added so much character to the broth.

In addition to the free noodles, which change each week, the temple provides a selection of vegan dishes for people to take home in exchange for donations, in a practice that will seem familiar to anyone whos been to a church fish fry or bake sale.

When you go, head past the steps leading up into the temple and make your way into the courtyard. Youll find someone crushing fresh sugar cane for juice ($5 for a pint). Flavorings are seasonal; mine was floral and bright with kumquat juice and zest. The cane is chopped and run through a hand-cranked press. In the Caribbean, this juice would go on to become rum, but the Vietnamese way is to consume it fresh.

The kitchen, where youll actually be able to buy food, is underneath the temple in an enclosed space. In the center of the room is a stall laden with food: glistening fried tofu flavored with minced lemongrass; Styrofoam trays of chow mein; a mushroom- and taro-stuffed bao with a perfect dough-to-filling ratio; and banana leaf-wrapped banh bot loc filled with tofu, minced carrot and wood ear mushroom. The banh bot loc, a dumpling made with steamed tapioca flour, is akin to fresh-made har gow and slip-slides down your tongue.

The spread varies week by week, but the fare is always vegan and allium-free, with the exception of the yogurt, which the nuns make from cows milk and sell in plastic cups. There are about 15 savory items and five dessert items on the menu, ranging from $1 to $8. The prices are suggested minimum donations, but you are free to donate more if the spirit moves you. (Theres a lot of single-use plastic and Styrofoam in play here, but you can bring your own containers.)

The dining area includes communal tables with plastic chairs and a central hub for flatware and napkins. If you decide to eat here rather than grabbing everything to-go, a volunteer will load up a plate for you of whatever you choose. Some of the tables are reserved for worshipers who are commemorating special occasions, but the tables without settings are available.

Spring rolls ($1 for two), filled with wood ear mushroom, mung bean noodles, jicama and dried daikon radish shreds, are savory and grease-free. They somehow taste just as rich and complex as my grandmothers, and theyre well-seasoned enough to be excellent even without the customary fish sauce dip. Your order will be tucked into a brown paper bag, toasty and warm like a handful of roasted chestnuts. Theyre nice to nibble as you browse the rest of the selection.

If youre lucky, youll find a seared and soy sauce-braised tofu skin roulade ($8) filled with wood ear mushrooms and lily buds. Its a shareable, burrito-size monster that the volunteers will cut up for you. I loved the tender layers of tofu, which had absorbed the slightly sweet and five-spice-tinged braising liquid and taken on the springy texture of thin wheat noodles.

The ingredients are wholesome and clearly very local: On a recent sunny afternoon, the staff was drying bowls and trays full of jujubes, shiso leaves, lime leaves and shredded daikon in the courtyard. Around the temple grounds, you can spot dragonfruit plants, collards, pomegranates and citrus trees. This is plant-based cuisine made concrete, with dishes from plants that had absorbed the same sun and oxygen that youre enjoying in that moment.

The binary political stereotype of the liberal, hippy-dippy Californian often includes vegetarianism as a pejorative, but the religious aspect of occasional meat-free eating seems strangely distant from that conversation. In some Catholic regions, abstaining from meat on Fridays is considered a charitable or pious act. Jains have long considered food containing meat, fish or eggs as one of the religions four maha-vigai, or great perversions. Within Judaism, some have argued for pro-vegetarian interpretations of the Torah and kosher laws. The conflation of meat-free diets with morality and self-discipline has a long history.

Vegetarianism here feels less like self-discipline and more like indulgence. Its not my community or religion, but I appreciate the reminder that our actions do have an impact on our personal karmic debts and on the world at large and that we dont truly live in isolation.

Soleil Ho is The San Francisco Chronicles restaurant critic. Email: soleil.ho@sfchronicle.com. Twitter @hooleil.

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Where do you find amazing vegan Vietnamese food in the Bay Area? Look for this Buddhist temple in East Palo Alto - San Francisco Chronicle

Precision NanoSystems to Launch the Revolutionary Ignite – Yahoo Finance

A Disruptive Technology Enabling Transformative Medicine

Vancouver BC, Oct. 09, 2019 (GLOBE NEWSWIRE) -- Precision NanoSystems (PNI) a global leader of innovative solutions for the discovery, development, and manufacture of nanomedicine based gene and cell therapies, small molecule and protein based drugs is pleased to introduce our newest member of the Nanoassemblr Platform: the Ignite availabe October 15, 2019.

The Ignite embodies everything that made the NanoAssemblr family of instruments the go-to platform for developing new Precision and Gene Therapy medicines for over 100 biopharma companies and featured in over 150 publications. said James Taylor, CEO & Co-Founder PNI. The Ignite brings our latest innovations developed for clinical manufacturing to the bench, and paves the way for new nanomedicine approaches to treat cancer, rare disease and infectious disease.

PNIs proprietary NxGen scalable continuous-flow microfluidic technology is at the heart of the NanoAssemblr family, using controlled mixing to reproducibly manufacture the highest quality drug products through a single mixer across scales. Ignite enables rapid benchtop scale development of nanoparticle based RNA, DNA, CRISPR, small molecule and protein therapeutics. Optimized drug products are predictably scaled to advanced preclinical and clinical scale with the NxGen technology on the NanoAssemblr Blaze and GMP Systems.

As the leading provider of RNA/DNA drug manufacturing, we designed Ignite with the end in mind developing a robust, scalable process from the earliest stage. Enabling researchers to create transformative medicines at the bench scale, said Euan Ramsay, CCO & Co-Founder PNI.

We are hitting the road and showcasing this revolutionary technology in a location near you. Find localWorkshopsor see Ignite and our complete NanoAssemblr Platform at theseconferences in 2019.

About: PNIs proprietary NanoAssemblr Platform enables the rapid, reproducible, and scalable manufacture of next generation nanoparticle formulations for the targeted delivery of therapeutic and diagnostic agents to cells and tissues in the body. PNI provides instruments,reagents and services to life sciences researchers, including pharmaceutical companies, and builds strategic collaborations to revolutionize healthcare through nanotechnology.

Attachments

Jane AllevaPrecision NanoSystems Inc.1+778 877 5473jalleva@precision-nano.com

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Precision NanoSystems to Launch the Revolutionary Ignite - Yahoo Finance

Rising adoption of minimally invasive treatments for chronic disorders across the globe will propel the growth of injectable nanomedicines market…

The globalinjectable nanomedicines markettouched USD 479.6 million in 2017, and is expected to reach USD 833.9 million by 2025, growing at a CAGR of 7.3% during 20182025.

Source: GMI Research

Major Factors driving the market growth are: Growing incidence of chronic diseases like cancer, cardiovascular diseases, neurological disorders Increasing research & development activities and clinical trials Rising demand and adoption of minimally invasive treatments Rising government and private funding Increasing geriatric population

Growing demand for minimal invasive treatments is driving the Injectable Nanomedicines market. Introduction of innovative and advanced nanotechnology and nanomedicines, especially in the emerging markets with the help of government and private funding would spur the growth of market for the injectable nanomedicines during the forecast period.

Request for Sample Report https://www.gmiresearch.com/report/global-injectable-nanomedicines-market-by-product/sample-request

A paradigm shifts from traditional therapeutics to novel therapeutics using nanomedicines is propelling the overall market as nanomedicines have higher payload capacity, prolonged blood circulation times, reduced toxicity and improved anti-tumour efficacy. Moreover, the application of injectable nanomedicines for some widespread chronic diseases like migraine and depression is also aiding market growth. The use of injectable nanomedicines are found to be efficient, lasting and easy treatment of many chronic cardiovascular and neurological disorders.

Growing incidence rate due to aging demographic patterns and the extension of health insurance coverage in a developing region will support the market growth. Advancements in cancer drug delivery and personalized cancer treatments, effective and safe treatment of medically refractory movement disorders and the need for fast and efficient cardiovascular systems will primarily drive the global injectable nanomedicine market.

The rising pool of patients of chronic diseases and the need for a fast, efficient and long-lasting treatment with minimal invasion procedures will drive the injectable nanomedicines market.-GMI Research

Based on geography, North America held the largest market share in 2017 due to the significantly high rate of incidence of cancer as well as cardiovascular diseases in the region. Currently, the region has a growing demand for rapid research & development of novel nanomedicine in order to address unmet medical needs. Furthermore, favourable reimbursement policies and increasingly growing partnerships between leading enterprises and nanomedicine start-ups is also expected to create growth opportunities. Europe is the second largest market in 2017 and is promising market due to developed healthcare system and rising adoption of nanomedicine in oncology sector. Asia-Pacific is expected to show promising growth in global injectable nanomedicines during 2018-2025 due to the increasing government and private funding for health care infrastructure along with the rising incidence of neurological disorders. Moreover, increasing adoption of nanomedicine for the treatment of cancer, diabetes, cardiovascular diseases and some infectious disease in the Asia-Pacific region would also contribute significantly to the market growth for injectable nanomedicines in the region.

Based on geography, North America held the largest market share in 2017 due to the significantly high rate of incidence of cancer as well as cardiovascular diseases in the region. Currently, the region has a growing demand for rapid research & development of novel nanomedicine in order to address unmet medical needs. Furthermore, favourable reimbursement policies and increasingly growing partnerships between leading enterprises and nanomedicine start-ups is also expected to create growth opportunities. Europe is the second largest market in 2017 and is promising market due to developed healthcare system and rising adoption of nanomedicine in oncology sector. Asia-Pacific is expected to show promising growth in global injectable nanomedicines during 2018-2025 due to the increasing government and private funding for health care infrastructure along with the rising incidence of neurological disorders. Moreover, increasing adoption of nanomedicine for the treatment of cancer, diabetes, cardiovascular diseases and some infectious disease in the Asia-Pacific region would also contribute significantly to the market growth for injectable nanomedicines in the region.

Key takeaways/key essentials: In 2017, the cancer treatment held the major share for the injectable nanomedicines market followed by the cardiovascular diseases segment. High demand and adoption rate for minimally invasive treatments in the recent past. Extended research and development activities are taking place using the injectable nanomedicines regarding the concept of targeted drug delivery system.

Some of the key players operating in the global market for injectable nanomedicines include Merck & Co., Inc., Lupin, Pacira Pharmaceuticals Inc., Celgene Pharmaceutical Co. Ltd., Amgen, Inc., Janssen Biotech Inc., Pfizer Inc., Hoffmann-La Roche Ltd., Teva Pharmaceutical Industries Ltd., Bausch & Lomb Inc. among others.

Theglobalinjectable nanomedicines markethas been segmented based on product type, indication type and key geographies. Based on the product type, global injectable nanomedicines market has been segmented into liposomes, micelles, nanocrystals and others. Based on indication type, the market has been segmented into cancers, central nervous system diseases, cardiovascular diseases, inflammatory diseases and others.

The research report global injectable nanomedicines market provides in-depth analysis of injectable nanomedicines market, globally, based on product type, indication and major geographies for the forecast period from 2018 to 2025. The report highlights the major market drivers fuelling the growth as well as challenges faced by the market participants. The research report provides market size and forecast for injectable nanomedicines market. The report also analyses the competitive landscape, major players and their strategies in 2018. The competitive landscape section of the report captures and highlights the recent developments in the market.

For more details, browse the Table of Contents:https://www.gmiresearch.com/report/global-injectable-nanomedicines-market-by-product/

Early buyers will get customization upto 20% on report

About GMI Research

GMI Research is a market research and consulting firm which provides research-based solutions to business executives and investment professionals so that they can make right business & investment decisions faster based on real facts. We help business leaders through independent fact-based insight, ensuring their business achieve success by beating the competition.

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Company Name: GMI RESEARCHContact Person: Media RelationsPhone: +353 1 442 8820Address:Level 1, The Chase Carmanhall Road, Sandyford Industrial EstateCity: DublinState: DublinCountry: IrelandWebsite:www.gmiresearch.com

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Rising adoption of minimally invasive treatments for chronic disorders across the globe will propel the growth of injectable nanomedicines market...

Doctor launches the first online clinic dedicated to using common drugs for a different purpose: to slow aging – CNBC

Dr. Zalzala hopes to serve the growing market of people interested in anti-aging treatments.

One of the many wild medical pursuits in Silicon Valley is the effort to slow down the aging process. Sajad Zalzala is trying to make it a reality.

Zalzala, a 38-year-old family medicine doctor based in the Detroit area, has just opened an online clinic called Qalytude, dedicated to anti-aging. As a physician licensed to practice in all 50 states, Zalzala can treat patients anywhere in the country by phone or online, in addition to those who visit his physical clinic.

Initially, Zalzala will be targeting the small but growing segment of Americans who take medicines like Metformin, a type 2 diabetes drug, but for the unintended purpose of staving off aging. Researchers are now finding evidence of reduced cancer risk in the drug, and studies in mice have shown potential for an improved life span, but scientists warn that it might not produce the same result in humans.

"There's this movement around Metformin that I could see having a snowball effect," Zalzala told CNBC.

He's jumping into a market for anti-aging services, products and technologies that's expected to reach $271 billion by 2024, according to Market Research Engine. Venture capital funds are dabbling in the space as are billionaires like Jeff Bezos and biohackers, who experiment with drugs and supplements for health and longevity purposes.

Zalzala said that only a few clinicians are trained in this field, and they're highly costly to see and often backed up with patients. Many primary care physicians won't prescribe Metformin to people who don't have diabetes until they better understand whether it's safe.

Zalzala's goal is to make it easier for people interested in drugs like Metformin to talk to a physician. He plans to hire a team of doctors to conduct research into Metformin and other drugs both their safety and efficacy and prescribe them virtually to patients while monitoring them for side effects.

Having previously worked for a handful of virtual medical companies, including Hims and Pill Club, Zalzala is familiar with the model. Hims and Roman are among companies that have sprung up in recent years to help people get medications for erectile dysfunction and hair loss, the types of things that patients are often embarrassed to discuss with a family doctor. Other companies are prescribing medication virtually for birth control, sexual health and prevention, anxiety and attention deficit hyperactivity disorder.

Some of these companies require that patients talk to their doctor via video, while others request only that the user fill out a survey. The laws that govern how engaged a physician must be in the process vary by state.

For an area like anti-aging, a medical expert needs to be highly involved in the process.

These drugs "always must be prescribed by a doctor," said Lisa Suennen, managing director of digital and technology at the law firm Manatt, Phelps and Phillips. "Any drug can be dangerous if it is mixed with something contraindicated," and it's especially important to be cautious when they're being used "for claims that aren't fully vetted."

The side effects for Metformin include diarrhea, low blood sugar and abdominal pain, as well as a condition called lactic acidosis that involves excessive acid building up in the body. It also still isn't well understood whether the drug will provide benefits to healthy people, particularly those who exercise regularly.

Another medicine Zalzala is exploring is rapamycin, which has an immunosuppressant function and is useful in helping patients avoid rejected transplanted kidneys. He's also looking into so-called NAD booster patches. Both interventions are starting to get tested in the Silicon Valley tech community for their anti-aging effects, even though there are health risks.

Zalzala said he intends to be especially conservative with these untested therapies, but he didn't rule out the possibility of prescribing them. He said that he will recommend lifestyle and dietary changes and not just pills.

"Most of us don't have the perfect lifestyle," he said. "So I'm hoping to add an extra layer of protection."

WATCH: Tech, health care will continue to lead the market

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Doctor launches the first online clinic dedicated to using common drugs for a different purpose: to slow aging - CNBC

Dr. Monica Jacob Obesity Consultant and Anti-Aging Physician in Mumbai – The India Saga

By TIS Staffer 09 Oct 2019

Dr. Monica Jacob is MBBS, M.D (Bom), She is an Aesthetic physician, Obesity Consultant, and Anti-Aging Physician.

She has been practicing for 16 years. She completed her M.B.B.S from J.J Group of hospitals, Grant medical college (Mumbai) in 1999, M.D. from TNMC, Nair medical college (Mumbai).

DPB from C.P.S in 2002.Diploma in aesthetic dermatology (American academy of aesthetic medicines), Nutrition & Diet planning (Australia, gold coast academy), Hair transplantation (American Acadamy of Aesthetic medicines), Anti-ageing medicine- hormones.

Her clinic offers the latest technologies for the treatment of various skin and hair ailments.

Dr. Monica Jacob is an amazing doctor. She is so vibrant and her good attitude is infectious. She is thorough and meticulous in her job. She is very friendly & equally professional. She helped her patients in understanding the reasons for the skin issues & also explained in detail various treatment procedures to address the same. In fact, Various patients highly recommended her.

Easy Remedies that she tells to Follow

1.Protect your skin from the sun every day. ...

2.Apply self-tanner rather than get a tan. ...

3.If you smoke, stop. ...

4.Avoid repetitive facial expressions. ...

5.Eat a healthy, well-balanced diet. ...

6.Drink less alcohol. ...

7.Exercise most days of the week. ...

8.Cleanse your skin gently.

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Dr. Monica Jacob Obesity Consultant and Anti-Aging Physician in Mumbai - The India Saga

Push-ups? Here’s what can really help you live to a ripe old age – The Australian Financial Review

The problem with any of these approaches is that you would just be training for a particular test, which misses the point. It's not the push-up itself that makes you live longer; it's that you are still strong and nimble enough to execute one.

What these tests have in common is they're good shorthand of things that matter for longevity: overall health, fitness and muscle strength. A fit person walks faster than someone out of shape, and getting up off the floor is tricky for people with weak bones and muscles.

"Frailty is a really bad thing starting in middle age, and even worse as you get older," says Michael Joyner, a physician and human physiology researcher at the Mayo Clinic.

One way to think of longevity is "not as some magic property of a body, but as the lucky state of not having a fatal disease", says Steve Cole, professor of medicine and psychiatry and bio-behaviouralsciences at the UCLA School of Medicine. "By and large, people don't die of being old; they die of disease." Therefore, the study of longevity is a way of looking at disease risk or the rate of disease development, he says.

Over the years, various drugs and nutritional supplements have been studied for their potential to help us live longer, but nothing has been shown to work in humans to the extent that would be required for the Food and Drug Administration's approval, says Gordon Lithgow, chief academic officer at the California-based Buck Institute for Research on Aging.

While researchers continue searching for a pill to extend life, you'll have to try these verified methods.

The most powerful way to promote longevity and improve your long-term health is also simple and, depending on how you do it, free.

"There's no question that exercise is the biggest anti-ageing medicine there's ever going to be - it's really huge," Lithgow says.

"Hands down, nothing compares to exercise," says Laura Carstensen, founding director of the Stanford Center on Longevity. "The great thing is that most people can do it, and you don't need 10,000 steps per day to get the benefits." It takes remarkably little exercise to get longevity benefits.

Even 10 to 15 minutes a day provides measurable rewards, says Michael Joyner, a physician and human physiology researcher at the Mayo Clinic. Going from sedentary to even just a bit of exercise is where you get the biggest payoffs. The health benefits - such as reducing your risk of heart disease and diabetes - increase with greater amounts of exercise, until you get to about an hour of exercise per day. After that, the rewards start to level off.

"Almost anyone doing more than that is doing it for things other than health," Joyner says.

Go ahead and train for that Ironman if that's what you want, but if you're exercising for health and longevity, you don't need to run a marathon. Work by Iowa State University epidemiologist Duck-Chul Lee suggests that even running a little less than 10 minutes a day could decrease your mortality risk by about 30 per cent.

But you don't have to run. Walking or other moderate activities are just as good if you're looking for a longevity boost.

Some of the early evidence for the heart benefits of moderate exercise came from studies in the 1950s by British epidemiologist Jeremy Morris showing that conductors on double-decker buses, who spent their shifts walking up and down, had lower rates of coronary heart disease and thus lived longer than bus drivers who spent their workday sitting. Since then, studies showing the cardiovascular benefits of exercise have been "incredibly consistent", Joyner says.

But there's more. Physical activity also reduces the risk of diabetes, which one study found shaved six years off life expectancy.

And it keeps your brain healthy, too. "Exercise has better effects on cognitive performance than sitting around playing brain games," Carstensen says. A 2006 study in Neuroscience found that exercise spurs the brain to release growth factors that promote new connections between neurons, keeping the brain healthy. There's even research suggesting that strength training can reverse some age-related changes in your muscles.

There seems to be something about keeping an active lifestyle, too.

When you look at centenarians as a group, they might not be Arnold Schwarzeneggers, but they typically maintain a high level of physical function, says author Bill Gifford, who interviewed quite a few of them while writing his book, Spring Chicken: Stay Young Forever (Or Die Trying). "They can go up and down stairs, probably because they never stopped going up and down stairs," Gifford says.

His research for the book spurred him to make sure he was exercising at least a little bit every day.

Extend your life span while you sleep. It sounds like a bad infomercial, but it turns out that sleeping well is a good way to keep your body healthy for the long haul. Sleep is a time when your brain gets caught up on maintenance. In 2013, a team led by Maiken Nedergaard at the University of Rochester Medical Center published a study in Science concluding that sleep helps the brain clear out metabolic waste that accumulated during waking hours, providing a kind of restorative maintenance.

Skimp on sleep, and you hinder this important work.

If you've ever missed a night of slumber, you know that sleep deprivation hampers your mood and makes it hard to think clearly, but it can have severe consequences for your metabolic health, as well. Take someone who needs seven hours of sleep a night and restrict them to only five hours of shut-eye for five nights and they experience metabolic changes that look a lot like diabetes, says Satchidananda Panda, who studies circadian biology at the Salk Institute for Biological Studies.

Indeed, numerous studies have shown that sleep deprivation can decrease insulin sensitivity - a measure of how well your body regulates blood sugar - and increase your risk of diabetes. A 2015 meta-analysis found that Type 2 diabetes risk was higher in people who sleep less than seven hours or more than nine hours, compared with people who got seven to eight hours a night.

So why is sleeping more than nine hours associated with greater mortality? "People who sleep 14 hours per day are probably not healthy," Carstensen says, but it's hard to say right now whether it's possible to get too much sleep. Most people are on the other end of the spectrum.

Regularly sleeping too long may indicate a health problem

The consensus among sleep researchers is that seven to eight hours of sleep is ideal, but that's just a best guess based on the current data, Carstensen says.

"The biggest problem is that most of the data is self-reported and people are really bad at that," Carstensen says.

The advent of sleep trackers can help with the measurements, but they aren't always accurate, so avoid fixating too much on the exact numbers or you may end up in a cycle of anxiety that prevents you from sleeping. The problem is common enough that researchers have coined a term for it - orthosomnia.

Don't make a habit of skimping on sleep during the week with the idea that you'll catch up on the weekends. It doesn't take many nights of short sleep to reduce insulin sensitivity, and a small study published this year in Current Biology found that recouping on sleep over the weekend didn't entirely make up for the metabolic problems that developed during sleep deprivation. Furthermore, when volunteers in the study were given the opportunity to catch up on sleep over the weekend, they ended up shifting their body clocks so that it became harder to get up on Monday morning.

(Getting enough sleep every night might also improve your work life. In the throes of writing his book, Gifford made a decision to start prioritising sleep over work. His deadline was fast approaching, and he'd been getting up early and staying up late. Allowing his body to sleep as long as it needed to led to a "radical transformation in my ability to write", Gifford says. "I'd been trying to work 14 hours per day, and then suddenly I was getting twice as much done in six or seven hours.")

Forget all those headlines you've seen about "anti-ageing diets" and anti-aging "superfoods".

"These notions are generally not supported by science," Lithgow says. That's not to say diet isn't important, only that "nutrition is just a very difficult science", he says.

Severely restricting calories in lab animals makes them live longer, but "it's not clear that it works in humans", Lithgow says. Although there's plenty of evidence that it's not good to overeat, he says, whether drastically limiting food intake can extend life in people remains an open question. The joke, of course, is that calorie restriction will surely make your life seem longer.

It might be possible to get some of the benefits of calorie restriction without giving up so much food. Intriguing work by Panda suggests that restricting the timing of when you eat, rather than the amount, might provoke some of the healthy metabolic changes that reduce the risk of diabetes. Most of these studies have been done in mice, however, and Panda acknowledges that the human studies are small.

Although Panda is confident enough in the results to have written a book, The Circadian Code, which includes instructions on how to try it, some scepticism is warranted, Joyner says.

"Time-restricted eating has shown some interesting results in small studies," Joyner says, but "will it be sustainable over time in the real world? This is important because most dietary strategies work only if they are adhered to."

He says he wonders whether the metabolic benefits that Panda has found with time-restricted eating is really about the timing or simply related to people eating less when their dining hours are restricted. One thing shown repeatedly in anti-ageing studies is that things that initially look like magic bullets never live up to their initial hype, Joyner says.

What does seem clear, however, is that metabolic health is important for long-term health, because it keeps diabetes in check and that insulin sensitivity in particular appears crucial.

Given what we know right now, a Mediterranean diet - with its heart-healthy emphasis on fish, vegetables, fruits, nuts, healthy fats like olive oil, whole grains and limited consumption of red meat - "is probably the best approach for improving longevity", Carstensen says.

But the benefits are pretty modest. If you hate eating that way, then the payoff probably won't feel worth it to you, she says. At least try to eat a diet rich in fruits and vegetables.

The idea of red wine as a health elixir became popular in the 1980s with the observation that rates of coronary heart disease were low in France, despite the predominance of a diet relatively high in fat and cholesterol. The French penchant for a glass of red wine with dinner was proposed as an explanation for this "French Paradox", popularisingthe notion of red wine as heart helper.

Subsequent studies have indeed found that moderate alcohol consumption may reduce the risk of coronary heart disease, and a two-year randomisedclinical trial in Israel showed that people with Type 2 diabetes who were assigned to drink a glass of red wine with dinner every night experienced some improvements in blood markers associated with cardiovascular disease risk.

But other studies suggest that alcohol may raise the risk of many cancers, and a report published last year in the journal Lancet concluded that there's no amount of alcohol that improves health. What gives?

"Alcohol studies are very much like nutrition studies - based almost exclusively on self-reports, and we know that people are really bad at self-reporting," Carstensen says. "Most people, when they say they're drinking two drinks per day, are probably consuming more. We don't know the amounts that people are consuming nor do we know what else they do."

There's some evidence that people who abstain from alcohol are sicker or less healthy than those who imbibe a little.

"That probably reflects not a lack of alcohol in their system, but something about their world - that they're sick or isolated or don't have friends to meet at the pub," Carstensen says. "I've never seen a study that's really controlled for all of those factors." Which means that the studies calculating the health consequences of alcohol consumption depend on consumption figures that are inherently unreliable and may fail to account for other factors that could be at play.

Drinking to excess - more than one or two drinks a day - is unhealthy, and will take a toll on your longevity - no doubt about it. But taking the published studies together, "I don't think we have a lot of evidence that moderate alcohol is bad for you," Carstensen says. At the same time, she'd "be very hesitant to recommend that people who don't drink should start".

In today's world, it's easy to live in a state of chronic stress, and the problem isn't just that stress feels lousy. It also makes you more susceptible to diseases that could shorten your life.

Researchers are now learning that many conditions associated with older age - such as cancer, heart attacks and Alzheimer's disease - share a common ingredient: inflammation.

Under normal conditions, inflammation is simply the body's response to injury - it's how the body heals cuts and wounds and other insults, Cole says. "Inflammation by itself is not inherently evil." But when we're feeling chronically threatened or under siege, our bodies amp up their inflammatory machinery to ready our biological response to injury, and that inadvertently fuels the development of an array of age-related diseases, where inflammation is a common fertiliser, Cole says.

Research has identified chronic stresses that can provoke harmful biological changes, including living in poverty, caregiving for a dying spouse, losing a loved one, suffering post-traumatic stress disorder, and experiencing prejudice.

"Any way of feeling threatened or insecure seems to be enough to activate the body to produce more inflammation," Cole says. "This is one of the best defined connections between the world as we experience it and how we end up generating a body that's a fertile ground for the development of these diseases."

Your chance of developing chronic inflammation also rises with the passing years. "Inflammation seems to be a general sign of aging, where our inflammatory processes are being turned on or accumulated," Lithgow says. "Age-related inflammation is very much like inflammation from an injury, but now it's coming on without a source of infection."

What's the antidote? "Obviously we should all just be happy," Cole says with a laugh, as if it were that easy. He knows that it's not and says you probably can't eliminate stress from your life, but you can find ways to manage it. Identify the recurring stressors in your life, and work on a plan to diffuse them.

Wellness strategies such as yoga, tai chi and meditation can reliably help diffuse stress, Cole says, although he acknowledges that they often don't make a huge difference.

Forging connections with other people has been found to be a powerful way to manage stress and improve your overall wellbeing.

"People who report having stronger relationships live longer than people who are socially isolated," Carstensen says. A meta-analysis published in 2015 calculated that loneliness and social isolation were associated with 29 per cent and 26 per cent increases in mortality risk, respectively, and living alone was linked to a 32 per cent increase risk of dying.

What's clear is that people who have a strong sense of purpose and meaning in their lives have a markedly lower risk of death than those who don't.

"How we can bottle that and make it useful is more of a challenge," says Cole, who has studied loneliness and longevity.

Telling a lonely person to stop being lonely doesn't work, Cole says, "but if you can go to the lonely person and say, 'Hey, we really need your help. Is there anything you can do to help others?' - that is incredibly powerful. The mechanism here seems to be turning attention away from yourself and your own suffering and toward a community or cause greater than yourself."

Centenarians tend to have a sense of purpose in their lives.

"It's really important that people who are entering the later phases of life have a clear purpose, something to get up for every day," Lithgow says. That thing can be anything from looking after a grandchild or working or tending a garden.

Many centenarians continued working into their 80s, 90s and beyond, Lithgow says, and usually these jobs are in environments where they interact with younger people.

Interacting with other generations can keep older people engaged, and some retirement communities and nursing facilities are now taking steps to give their residents opportunities to connect with kids - for instance, placing kindergarten classrooms in nursing homes.

Most of the proven tips for living a long, healthy life are not products that you buy, but good lifestyle habits that you adopt (or bad ones, such as smoking, that you either quit or never take up and are clearly associated with diminished longevity).

Even something as simple as always wearing a seat belt can reduce your chances of dying early. Most of the things that make up a longevity lifestyle are simple - exercise, eat (and drink) healthily, sleep adequately, stay engaged - if only people would do them.

"To me, the bottom line is: Live a reasonably moderate life and you'll be OK," Carstensen says.

Washington Post

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Push-ups? Here's what can really help you live to a ripe old age - The Australian Financial Review

Ingredient Spotlight on Snow Mushroom – Truth In Aging

Snow mushroom or tremella fuciformis (also known as snow fungus, snow ear, silver ear fungus and white jelly mushroom) starts out as a slimy, mucous-like film until it encounters its preferred hosts. Then it grows into an ethereally pretty white cloud that is gaining a well-deserved reputation in anti-aging skincare.

Tremella is one of natures natural sponges. It is said that it can hold 500 times its weight in water.This is about half as much as hyaluronic acid, which behaves in a similar way to draw in moisture and retain it. But snow mushroom has so much more going for it than hyaluronic.

For a start, snow mushroom can create a flexible hydration film that helps to restore dry skin to its optimally hydrated state. The molecular size of the extract is smaller than hyaluronic acid (a notoriously clunky molecule) and this means it can penetrate the skin more easily.

Then this shroom just keeps getting better. Scientists have demonstrated that it exhibits potent antioxidative, anti-inflammatory and anti-aging effects. Wondering why, they discovered that snow mushroom protects fibroblasts via the upregulation of SIRT1 expression. This has to do with sirtuins, which regulate the activity of the genes responsible for metabolism, cell defense and reproduction. When food is scarce, the body's sirtuins go into self-preservation mode. So giving your sirtuins a boost is a good thing.

Tremella fuciformis is a traditional nutritional food in China and is used as a traditional Chinese medicine and dietary supplement. Recent studies have indicated that the medicinal and tonic properties of tremella fuciformisare due to its polysaccharides, which are anti-inflammatory. Polysaccharides in skincare also reduce transepidermal water loss, protecting the skin barrier function.

Researchers have also demonstrated that snow mushroom oxidative stress and apoptosis in skin fibroblasts in a concentration-dependent manner and possessed excellent antioxidative properties. (source). It also efficiently reduced water and collagen loss in the skin and inhibited the increase of glycosaminoglycans.

A few other claims are less well documented (at least not that I can find), but Ill record that snow mushroom has also been shown to inhibit melanin production by 59.7%. It is also said to be comprised of over 18 kinds of amino acids and is a source of vitamin D.

Find tremella in hMSC Skincare Amplify ($160 in the shop), Cannatera Renew Facial Moisturizer ($69 in the shop), Cannatera Revive Serum ($79 in the shop), and Dr. Dennis Gross Alpha Beta Pore Perfecting Cleansing Gel ($32 in the shop)

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Ingredient Spotlight on Snow Mushroom - Truth In Aging

Teresa Sievers: The life behind the murder victim – Wink News

FORT MYERS

While you may know her face and you probably know the name, who was Dr. Teresa Sievers before she was a murder victim?

Ladies, remember when walking into a room meant turning heads? said Teresa in a YouTube video. You had that glowing skin, in-shape body. Didnt you feel sexy and confident?

Teresa was used to commanding attention. She was always dressed to perfection, always in heels and her middle name was literally Grace.

She was a tiny thing like you and just as cute as a bugs ear, said a former patient, Marian Ziegler-McAfee. Uplifting, positive, full of energy, a dynamo, a dynamo in a tiny package.

Teresa was only 411. When patients like Marian got to know her, they appreciated her, even loved her.

Several people said that she was like the Oprah Winfrey of Florida, Marian said. That she was that popular.

MORE:Teresa Sievers murder trial pushed back, date undecided

Teresa grew up in Connecticut. She was her high school valedictorian and later on graduated medical school with honors. When the new doctor moved to Charleston, she met her first husband, Kenny Cousins.

I believe this is the sort of person you might meet once in your life, Kenny said. When I met Theresa, she was doing clinical research in South Carolina. Some of the ways that we connected certainly love of the outdoors, the ocean, music, food and really having a good time. The real kind of a work hard, play hard ethic.

The pair moved to Saint Pete where Teresa worked at an outpatient clinic in a disadvantaged part of town.

She didnt think it was fair that she would have to have two or 3,000 patients, Kenny said. She could literally only spend 15 minutes with each of those patients.

MORE:Attorneys motion contains disturbing detail of Sievers murder

Three years after they married, Teresa and Kenny divorced. But Kenny said they remained dear friends. Even when Teresa remarried to Mark Sievers a few months later, they kept in touch, emailing monthly a couple of short lines with life updates.

She really felt restricted to be a doctor and thats one of the reasons when she got remarried to Mark, Kenny said. They bought a practice in the Fort Myers area where she wasnt taking medical insurance because it sort of lifted that burden.

It was a calling she had and she fulfilled it in an exceptional way. It was not a 15-minute visit; it was an hour and a half a visit, Marian said. Im grateful that I got that in this lifetime. Thats how rare she is.

For her patients, her medicine lives on in a series of videos on a YouTube channel, which focuses mainly on anti-aging. Many women turned to her for help through menopause. It was a group of women she was talking to when she said something that now has the kind of irony that makes you think.

I dont know about you, but Im not ready for post-mortem, said Teresa in a YouTube video. I want to enjoy my life like it is now.

MORE:From dreams to nightmare, key witness describes life before, after Sievers killing

Teresa had a beautiful life or at least that is how it looked.

Almost a year to the day after that video was uploaded, Teresa was murdered. She came back early from a family trip while Mark and their two daughters stayed in Connecticut.

Teresa rolled her suitcase into an attack in her kitchen.

Is she awake? the dispatcher said.

No she is dead on the floor, the caller said. Shes cold. The back of her head is bashed in and there is blood everywhere.

WINK News Anchor Amanda Hall first interviewed Kenny in 2015, shortly after the killing.

I mean my God shes 411 and defenseless and by herself, Kenny said. If there were problems in their marriage, why couldnt they just get divorced?

As Mark awaits trial for plotting his wifes murder, Kenny wants people to focus on how special she was.

This is the Teresa. This is the person that I know. This is the person that I care about and respect and honor, Kenny said. I really want people to understand this is a loving, kind, caring nurturing mother and physician. This is a person that wanted to and I believe made an impact on everyones life that she touched.

Will he ever find peace? Teresa may have answered that best in one of her YouTube videos.

Is it a guarantee? Teresa said. No. Theres no guarantees in life.

Its hard to find peace knowing that somebody that you know and love and care about and you always want the best for has been taken this way, Kenny said. I havent been able to get my arms around any of that yet. I dont know if I ever will.

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Teresa Sievers: The life behind the murder victim - Wink News