From Mediterranean Lentil Salad to Cinnamon Raisin Bread: Our Top 10 Vegan Recipes of the Day! – One Green Planet

Ready, set, recipes! Here are our just published, fresh-out-the-mill recipes in one convenient place! These are the top vegan recipes of the day, and are now a part of the thousands of recipes on ourFood Monster App! We have cauliflower chocolate mousse, Mediterranean lentil salad, and the ultimate guacamole recipe, so if youre looking for something new and delicious, you are sure to find a new favorite!

Source: Cauliflower Chocolate Mousse

If youre looking for a much healthier and more nutritious version of chocolate mousse, youve got to try this Cauliflower Chocolate Mousse by Mitra Shirmohammadi. Theres more than a full serving of vegetables in each cup, its free from refined sugar, and also super allergy-friendly (no dairy, eggs, soy, or gluten). Cauliflower is one of those miraculous vegetables that works incredibly well in both sweet and savory dishes. Theres no way anyone can ever tell there are vegetables hidden in your chocolate mousse! If you have picky eaters at home, this cauliflower chocolate mousse is a great way to get them to eat more veggies without even realizing it!

Source: Cinnamon Raisin Bread

Vegan and gluten-free cinnamon raisin bread thats refined sugar free and packed with raisins and texture. Made extra cinnamon-y with a secret ingredient! Its easy to make and only takes 1-bowl (and plenty of cinnamon and raisins.) This Gluten-Free Cinnamon Raisin Bread is a little less table bread and a lot more dense bakery- style bread. Its hearty, naturally sweet, and packed with protein and fiber.The combination of ground cinnamon and cinnamon kombucha adds the perfect amount of spice. Its hearty enough to serve for a breakfast bread or nutritious snack but sweet enough to also function as a healthful dessert. For even more texture, try adding walnuts or almonds when folding in the raisins. Serve your slices of gluten-free Cinnamon Raisin Bread by Lauren Kirchmaier warm with a big smear of almond butter slathered on top.

Source: Vegan Scampi in Lemon Garlic White Wine Sauce

This is a really simple dish that tastes elegant. Hearts of palm are the perfect stand-in for scallops. They have a similar look when sliced and a briny quality reminiscent of seafoodgreat for those with a shellfish allergy. This Vegan Scampi in Lemon Garlic White Wine Sauce by Jenn Sebestyen is elegant and delicious!

Source: Savory Granola

The amazing thing about granola is that you can, just like banana ice cream, use the basic recipe, exchange the spices and make your own combination. This savory granola recipe is perfect for topping your salad and soups or just munching on as a midday. It only takes about 20-30 min to make and the ingredients are pretty simple. You have to try this Savory Granola by True Foods Blog!

Source: Chocolate Pie

Chocolate and pie what could be better? This Chocolate Pie by Lenia Patsi is the ideal dessert to make this weekend. Simple and decadent!

Source: Protein Apple Berry Crumble

Vegan apple berry crumble is the perfect Autumn dessertits cozy, comforting, cinnamon-spiced & absolutely irresistible! This isnt however a standard crumble recipe. This is a healthy, refined sugar and gluten free crumble with added protein. You are going to love this Protein Apple Berry Crumble by Vicky Coates!

Source: Mediterranean Lentil Salad

This Mediterranean Lentil Salad by Medha Swaminathan is the perfect reset after a weekend of eating things that seemingly all contain massive amounts of vegan cream, cheese, and/or cream cheese. Its super easy to make, so your food-fatigued body doesnt have to do much work. Plus, its really good for you.

Source: Gado Gado Salad With Nut-Free Sauce

A mixed vegetable Indonesian-style salad served with nut free sauce dressing. The medley of vegetables with potato and tofu added make this salad a tasty, nutritious, attractive and colorful dish. This Gado Gado Salad by Daphne Goh is not only naturally gluten free but also vegan, egg free, nut free and refined sugar free. For soy free, simply omit the fried tofu and add some pumpkins for protein.

Source: Crispy Flavorful Pickles

A super quick recipe for yummy, full-of-flavor pickles. Have these Crispy Flavorful Pickles by Caroline Ginolfion the side of your preferred vegan dinner!

Source: The Ultimate Guacamole

This is the The Ultimate Guacamole by Christina Bedetta. Serve it with chips and fresh vegetables or enjoy it in wrap form. Its easy to make and is a great addition to so many dishes. Made with creamy avocado, red onion, tomatoes, and spices there is no arguing that this is the ultimate guacamole recipe. With such delicious flavors and versatility, the possibilities are endless!

We also highly recommend downloading ourFood Monster App, which is available foriPhone, and can also be found onInstagramandFacebook. The app has more than 15,000 plant-based, allergy-friendly recipes, and subscribers gain access to new recipes every day. Check it out!

For more Vegan Food, Health, Recipe, Animal, and Life content published daily, dont forget to subscribe to theOne Green Planet Newsletter!

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From Mediterranean Lentil Salad to Cinnamon Raisin Bread: Our Top 10 Vegan Recipes of the Day! - One Green Planet

Chiropractor Denver Announces Hormone Replacement Therapy Colorado Springs to Transform Life of Aging People – Press Release – Digital Journal

Colorado Medical Solutions brings Hormone Replacement Therapy Denver that can keep patients young by overcoming their aging related complications.

People in Denver and Colorado can now fight their aging problem with the perfect Hormone Replacement Therapy offered by Colorado Medical Solutions. The anti-aging clinic is located in Denver and Colorado Springs, and specializes in hormone replacement therapies and functional medicines for both men and women. The clinics Hormone Replacement Therapy Denver is ideal for men and women who want to remain young and feel youthful forever. The therapy helps aging people in overcoming their sluggishness and to feel more energetic to work with more energy.

According to the spokesperson of the clinic, people may come across many types of physical or emotional complications with the growing age. While the aging process cannot be reversed, but there are certain therapies that can delay the age related complications. They offer bio-identical hormone replacement therapy that brings transformative results both in men and women. The spokesperson reveals that the male population often experiences a hormonal imbalance after the age of 40 years. In some men, the complication may appear earlier or later. However, the problem can cause several kinds of medical conditions and to avoid these complications, men can take advantage of the Hormone Replacement Therapy Colorado Springs.

The problem of hormonal imbalance trouble many women as well. The common HRT for women include estrogen therapy, progesterone therapy, thyroid treatment, and testosterone replacement therapy. The Chiropractor Denver offers a set of hormonal replacement therapies for women to avoid common menopause symptoms. Many women complain of symptoms, such as night sweats, hot flashes, cramping, breast tenderness, vaginal dryness, and others due to hormonal imbalance only. The clinic offers female hormone optimization, so that a woman will not to suffer from such complications any more. The HRT for women helps improve a womans condition after the menopause.

Colorado Medical Solutions also specializes in regenerative medicine or IV Therapy Colorado Springs. In this therapy, a human beings cells, tissues or an organ can be replaced to restore normal human functions, which otherwise may have affected due to aging or any other reason. The clinic employs the most cutting-edge technology to offer the IV therapy to alleviate the pain and sufferings of the patients. The clinics advanced stem cell therapy is a comprehensive procedure to overcome the cell or tissue loss in humans due to aging. The clinic also excels in providing Platelet Rich Plasma therapy or PRP therapy in which blood can be injected into any body part to increase the healing potential of the organ.

One can learn more about these advanced therapies by visiting the website https://coloradomedicalsolutions.com

About Colorado Medical Solutions

Colorado Medical Solutions is an Anti-Aging and Functional Medicine Clinic with two locations in Denver and Colorado Springs. The clinics specialize in Bio-Identical Hormone Replacement Therapy (HRT) for men and women, Regenerative Medicine and IV Therapy. Furthermore, they offer an array of regenerative medicine modalities, such as Stem Cell Therapy, Medical Weight Loss ED Treatment and other sexual enhancement options for men and women.

Media ContactCompany Name: Colorado Medical Solutions Contact Person: Dr. Dean JonesEmail: Send EmailPhone: +1 (720) 550-6907City: DenverState: COCountry: United StatesWebsite: https://coloradomedicalsolutions.com/

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Chiropractor Denver Announces Hormone Replacement Therapy Colorado Springs to Transform Life of Aging People - Press Release - Digital Journal

World Pancreatic Cancer Day: increasing awareness and inspiring action – UNSW Newsroom

Pancreatic cancer is an insidious disease itis often diagnosedat an advanced stage, with about 90% of patients dying within five years of diagnosis.New projections suggest pancreatic cancer will be the second leading cause of cancer mortality by 2025.

This World Pancreatic Cancer Day, we are celebrating some of the many UNSWresearchers who are dedicated to changing those statistics. Cancers with poor outcomes like pancreatic cancer are a key focus area in UNSW Medicine's cancer theme.

Associate Professor Phillips is the Head of the Pancreatic Cancer Translational Research Group and Deputy Director of the Adult Cancer Program at the Lowy Cancer Research Centre at UNSW Medicine.

This year, A/Prof Phillips was a key driver in establishing the Pancreatic Cancer Research Hub, which aims to double the survival of patients with pancreatic cancer by 2030.

She says World Pancreatic Cancer Day is a powerful advocacy event to increase community and government awareness of pancreatic cancer.

It is also a time to reflect on the progress we have made in understanding this terrible disease and focus on the next steps to overcome current clinical challenges to ensure our research efforts bridge the gap and, as in other cancers, improve the outcomes for our patients with pancreatic cancer.

I know that we are on the brink of overturning the unacceptable statistics. Uniting researchers with the community who, unlike in other cancers, dont often get to be a strong voice advocating for themselves and Government will ensure Australian researchers continue to make positive change for pancreatic cancer patients globally.

A/Prof Phillips group has developed a novel cutting-edge way to keep pieces of human pancreatic tumours alive in the laboratory for two weeks after surgical resection.

Our capacity to grow human tumour tissue in the laboratory provides a valuable new clinical tool to test how a patients tumour responds to different chemotherapies and has the potential to immediately inform patient treatment options. Our unique tumour model is superior to other models because it is human in origin and it contains the complex tumour environment present in patients.

In 2016 A/Prof Phillips had a major breakthrough, successfully developing a novel nanomedicine a tiny drug delivery vehicle consisting of a state-of-the-art nanoparticle that can package gene therapy to inhibit any tumour-promoting gene in pancreatic cancer.

With the generous support from the Brian O'Neill Pancreatic Cancer Fundraising Dinner held last night the team will be able to perform essential preclinical studies to test the therapeutic potential of their nano-gene therapy in combination with a clinically approved drug. They also plan on using their expertise to improve the bioavailability of the clinically approved drugs using a nanomedicine approach.

Professor Minoti Apte was the first in the world to isolate and characterise pancreatic stellate cells, a cell type that is now known to play a major role in the progression of both chronic pancreatitis and pancreatic cancer. Coming up with ways to target these cells to prevent them from doing harm is now a major focus of her teams research.

The group has now shown that interrupting the cross-talk between cancer cells and surrounding cells in the microenvironment by targeting a certain signalling pathway reduces tumour growth and eliminates metastasis in early as well as advanced pre-clinical models of pancreatic cancer.

We have also shown that targeting this pathway reduces the risk of recurrence and progression after surgical resection of pancreatic cancer in a mouse model, and are currently working on possible pathways to take our laboratory findings to the clinic, Professor Apte says.

To me, World Pancreatic Cancer Day is a great opportunity to raise awareness in the community about this deadly cancer, but it is also a day to admire the courage and resilience of patients and their carers. These are the people that spur us researchers on to continue working hard to develop new therapeutic approaches to improve outcomes.

Last year, Professor Apte received the Gastroenterological Society of Australia (GESA) Distinguished Researcher Prize 2018. In 2014 she was awarded the Medal of the Order of Australia (OAM), after being named the NSW Woman of the Year in 2015. She was also the 2016 recipient of the Professor Rob Sutherland AO Make a Difference Award at the NSW Premiers Awards for Outstanding Cancer Research an award that recognises highly successful research that is actively changing cancer treatment and improving patient survival.

Dr Angelica Merlot, who is based at the Childrens Cancer Institute, focuses her research on developing new anti-cancer drugs that target drug resistance and suppress cancer spread.

This year, the cancer researcher has won the 2019 NSW Young Woman of the Year award for her achievements and research into treatments for pancreatic and brain cancer. She also won a 2019 Young Tall Poppy Science Award and the 2019 NSW Early Career Researcher of the Year (Biological Sciences) at the NSW Premiers Prizes for Science & Engineering.

Dr Merlot says today is an important day to raise awareness about one of the world's toughest cancers.

This is crucial as it broadens community knowledge, inspires action and supports further research funding for this cancer. It's also a time to remember those whom we have lost and those currently fighting this disease, she says.

Although we've seen a small improvement in the current survival rate, a lot of progress is still required. Further translational research means that there is a greater likelihood that the survival rates can be increased and the journey and treatment of those affected by the cancer can be improved.

Dr Merlot became focused on cancer research as an undergraduate. Her interest in aggressive cancers, such as pancreatic and brain cancer, was motivated by lack of improvement in survival rates over the past decades, largely due to late diagnosis, a lack of screening programs, low awareness of symptoms and a lack of treatment options.

After moving to UNSW Medicine as a Scientia Fellow in 2018, Dr Merlot focused on understanding the mechanisms by which cancer cells grow and adapt to their environment, why drugs become less effective and the development of nanoparticles to improve drug delivery.

Dr Merlots current projects are investigating part of a human cell called the endoplasmic reticulum (ER). The ER is a type of organelle, or subunit within a cell, that has been shown to help cancers grow, spread and develop drug resistance.

Dr Ying Zhu will lead a team of researchers from UNSW to discover much needed early detection methods for pancreatic cancer patients: the UNSW Medicine researcher today received $100,000 grant from the Avner Pancreatic Cancer Foundation. A/Prof Phillips is a co-investigator on this grant.

As current approaches to this research are time and labour intensive, the team will develop an integrated and small device based on nanotechnology for rapid and sensitive exosome analysis. The team will define a set of biomarkers that can differentiate between cancer and non-cancer subjects from cells and plasma carrying early signs of human pancreatic cancer. This novel technology will also be applicable for doctors monitoring the development and customising the treatment of a patients tumour.

Pancreatic cancer is difficult to diagnose in the early stages. Early tumour cant be observed during routine physical exams as the pancreas is deep inside the body. Most patients are diagnosed when the cancer has become very large or has spread to other organs. A method to detect pancreatic cancer early on is urgently needed, Dr Zhu said.

My project team aims to develop a blood test to detect pancreatic cancer in the early stages. The team will target exosomes, which are nanosized fragments released by cancer cells. Exosomes are important for communicating messages and transporting materials between cells. Exosomes have been identified as more accurate and promising biomarkers, or biological clues for pancreatic cancer diagnosis, Dr Zhu continued.

We are pleased to award funding to this innovative project, said Michelle Stewart, CEO of the Avner Pancreatic Cancer Foundation. We are encouraged by the high calibre of the research and believe that investment into projects like these will help us to increase survival for people diagnosed with pancreatic cancer.

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World Pancreatic Cancer Day: increasing awareness and inspiring action - UNSW Newsroom

What it means to be a cyborg in 2019 – Quartz

I have a four-foot-tall robot in my house that plays with my kids. Its name is Jethro.

Both my daughters, aged 5 and 9, are so enamored with Jethro that they have each asked to marry it. For fun, my wife and I put on mock weddings. Despite the robot being mainly for entertainment, its very basic artificial intelligence can perform thousands of functions, including dance and teach karate, which my kids love.

The most important thing Jethro has taught my kids is that its totally normal to have a walking, talking machine around the house that you can hang out with whenever you want to.

Given my daughters semi-regular use of smartphones and tablets, I have to wonder how this will affect them in the future. Will they have any fear of technologies like driverless cars? Will they take it for granted that machine intelligences and avatars on computers can be their best friends, or even their bosses?

Will marrying a super-intelligent robot in 20 years be a natural decision? Even though I love technology, Im not sure how I would feel about having a robot-in-law. But my kids might think nothing of it.

This is my story of transhumanism.

Courtesy of Zoltan Istvan

My transhumanism journey began in 2003 when I was reporting a story for National Geographic in Vietnams demilitarized zone and I almost stepped on a landmine.

I remember my guide roughly shoving me aside and pointing to the metal object half sticking out of the ground in front of me.

I stared at the device that would have completely blown my legs off had my boot tripped the mine. I had just turned 30. The experience left me shaken. And it kept haunting me.

That night as I lay tense and awake in my hotel room, I had the epiphany that has helped define the rest of my life: I decided that the most important thing in my existence was to fight for survival. To put it another way: My goal was to never die.

Because I was not religious, I immediately turned to the thing that gave meaning to my world: science and technology. I took a leap of faith and made a wager that day. I later called this (and even later, dedicated a book to it) the transhumanist wager.

The life extension business of transhumanism will be a $600 billion industry by 2025.

My idea for an immortality wager came from Pascals Wager, the famous bet that caught on in the 17th century that loosely argued it was better to believe in God than not to, because you would be granted an afterlife if there was indeed a God. My transhumanist wager was based in my belief that its better to dedicate our resources to science and technology to overcome death while were still aliveso we dont ever have to find out whether there is an afterlife or not. It turns out I wasnt alone in my passion to live indefinitely through science. A small social movement, mostly of academics and researchers, were tackling similar issues, starting organizations, and funding research.

Some of them called themselves transhumanists.

Fast-forward 16 years from my landmine incident, and transhumanism has grown way beyond its main mission of just overcoming death with science.

Now the movement is the de facto philosophy (maybe even the religion) of Silicon Valley. It encapsulates numerous futurist fields: singularitarianism, cyborgism, cryonics, genetic editing, robotics, AI, biohacking, and others.

Biohacking in particular has taken offthe practice of physically hacking ones body with science, changing and augmenting our physiology the same way computer hackers would infiltrate a mainframe.

Its pretty obvious why it has emerged as such a big trend: It attracts the youth.

Not surprisingly, worrying about death is something that older people usually do (and, apparently, those younger people who almost step on landmines). Most young people feel invincible. But tell young people they can take brain drugs called nootropics that make them super smart, or give them special eye drops that let them see in the dark, or give them a chip implant that enhances human ability (like the one I have), and a lot of young people will go for it.

In 2016, I ran for the US presidency as the Transhumanist Party nominee. To get support from younger biohackers, my team and I journeyed on the Immortality Busmy 38-foot coffin-shaped campaign busto Grindfest, the major annual biohacking meet-up in Tehachapi, California. In an old dentists chair in a garage, biohackers injected me with a horse syringe containing a small radio-frequency-identification implant that uses near-field communication technologythe same wireless frequency used in most smartphones. The tiny deviceits about the size of a grain of ricewas placed just under the skin in my hand. With my chip, I could start a car, pay with bitcoin, and open my front door with a lock reader.

Four years later, I still have the implant and use it almost every day. For surfers or joggers like myself, for example, its great because I dont have to carry keys around.

One thing I do have to navigate is how some religious people view me once they understand I have one. Evangelical Christians have told me that an implant is the mark of the beast, as in from the Bibles Book of Revelations.

Even though Im tagged by conspiracy theorists as a potential contender for the Antichrist, I cant think of any negatives in my own experiences to having a chip implant. But as my work in transhumanism has reached from the US Military to the World Bank to many of the worlds most well-known universities, my chip implant only exasperates this conspiracy.

While people often want to know what other things Ive done to my body, in reality becoming a cyborg is a lot less futuristic and drastic than people think.

For me and for the thousands of people around the world who have implants, its all about functionality. An implant simply makes our lives easier and more efficient. Mine also sends out pre-written text messages when peoples phones come within a few feet of me, which is a fun party trick.

But frankly, a lot of the most transformative technology is still being developed, and if youre healthy like me, theres really not much benefit in doing a lot of biohacking today.

I take nootropics for better brain memory, but theres no conclusive research I know of that it actually works yet. Ive done some brainwave therapy, sometimes called direct neurofeedback, or biofeedback, but I didnt see any lasting changes. I fly drones for fun, and of course I also have Jethro, our family robot.

For the most part, members of the disabled community are the ones who are truly benefiting from transhumanist technologies today. If you have an arm shot off in a war, its cyborg science that gives you a robot arm controlled by your neural system that allows you to grab a beer, play the piano, or shake someones hand again.

But much more dramatic technology is soon to come. And the hope is that it will be availableand accessibleto everyone.

I asked to be added to a volunteer list for an experiment that will place implants in peoples brains that would allow us to communicate telepathically, using AI. (Biohacking trials like this are secretive because they are coming under more intense legal scrutiny.)Im also looking into getting a facial recognition security system for my home. I might even get a pet dog robot; these have become incredibly sophisticated, have fur softer than the real thing (that doesnt shed all over your couch or trigger allergies) and can even act as security systems.

Beyond that, people are using stem cells to grow new teeth, genetic editing to create designer babies, and exoskeleton technology that will likely allow a human to run on water in the near future.

Most people generally focus on one aspect of transhumanism, like just biohacking, or just AI, or just brainwave-tech devices. But I like to try it all, embrace it all, and support it all. Whatever new transhumanist direction technology takes, I try to take it all in and embrace the innovation.

This multi-faceted approach has worked well in helping me build a bridge connecting the various industries and factions of the transhumanist movement. Its what inspired me to launch presidential and California gubernatorial campaigns on a transhumanist platform. Now Im embarking on a new campaign in 2020 for US president as a Republican, hoping to get conservatives to become more open-minded about the future.

The amount of money flowing into transhumanist projects is growing into many billions of dollars. The life extension business of transhumanism will be a $600 billion industry by 2025, according to Bank of America. This is no time for transhumanism to break apart into many different divisions, and its no time to butt heads. We need to unite in our aim to truly change the human being forever.

Transhumanistsit doesnt matter what kind you arebelieve they can be more than just human. The word natural is not in our vocabulary. Theres only what transhumanists can do with the tools of science and technology they create. That is our great calling: to evolve the human being into something better than it is.

Because transhumanism has grown so broadly by now, not all transhumanists agree with me on substantially changing the human being. Some believe we should only use technology to eliminate suffering in our lives. Religious transhumanists believe we should use brain implants and virtual reality to improves our morality and religious behavior. Others tell me politics and transhumanism should never mix, and we must always keep science out of the hands of the government.

We need unity of some significant sort because as we grow at such a fast rate there are a lot of challenges ahead. For example, the conservative Christian Right wants to enact moratoriums against transhumanism. The anarcho-primativists, led by people like the primitivist philosopher and author John Zerzan (who I debated once at Stanford University), want to eliminate much technology and go back to a hunting-gathering lifestyle which they believe is more in tune with Earths original ecology. And finally, we must be careful that the so-called one percent doesnt take transhumanist technology and leave us all in the dust, by becoming gods themselves with radical tech and not sharing the benefits with humanity.

I personally believe the largest danger of the transhumanist era is the fact that within a few decades, we will have created super-intelligent AI. What if this new entity simply decides it doesnt like humans? If something is more sophisticated, powerful, intelligent, and resilient than humans, we will have a hard time stopping it if it wants to harm or eliminate us.

Whatever happens in the future, we must take greater care than we ever have before as our species enters the transhumanist age. For the first time, we are on the verge of transforming the physical structure of our bodies and our brains. And we are inventing machines that could end up being more intelligent and powerful than we are. This type of change requires that not only governments act together, but also cultures, religions, and humanity as a whole.

In the end, I believe that a lot more people will be on board with transhumanism than admit it. Nearly all of us want to eliminate disease, protect our families from death, and create a better path and purpose for science and technology.

But I also realize that this must be done ever so delicately, so as not to prematurely push our species into crisis with our unbridled arrogance. One day, we humans may look back and revel in how far our species has evolvedinto undying mammals, cyborgs, robots, and even pure living data. And the most important part will be to be able to look back and know we didnt destroy ourselves to get there.

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What it means to be a cyborg in 2019 - Quartz

The Most Elaborate Display of Ineptitude I Have Ever Witnessed: The BiChip Hoax – Patheos

The first email was forwarded back and forth internally for a while due to a general sense of skepticism and a lack of clear interest:

From: S E

Date: Fri, Sep 13, 2019 at 1:12 PM

Subject: Bichip Mark of the beast

Hail Satan

Hope you are all fine

I am writing to you since our Human Microchip company is having a big international event here in Copenhagen, November 26th. We are unveiling the cutting edge technology of human microchip implant with long distance read and internet data, for the first time in the history that is also known as the mark of the beast in the bible of Jesus and we have been facing opposition from churches and even been in the news for that:

‘Transhumans’ reveal why they want everyone to implant chips under their skin

Anyway, here is the link to the event is bichip.com/event

I wonder if you guys would like to help us promote the event which is actually free to attend? there are about 400 seats left yet and we can provide free VIP tickets to the temple members (Including free Flight and Accommodation)

Best

Simon

Bichip, Denmark

+4531751127

Professional emails lacking in basic details are, unfortunately, the norm. I receive emails from career journalists at major media outlets sometimes saying nothing more than that they would like to interview me. I get invitations to conferences that merely state that they seek my participation, leaving it to me to ask if they are asking me to speak, seeking sponsorship, or what, exactly? The fact that this email merely asked if we would help promote the event did not make it particularly suspect. The fact that there was apparently no cap set on flights and accommodations, however, was suspect, but could easily be seen as another common failure to specify. If one were to reply, one might then learn that a plus one is acceptable, but no more. It also is not unheard of for a start-up with delusions of grandeur to overspend on something like a conference. Still, they seemed to be offering too much while asking for too little.

Interestingly, the reference to the Mark of the Beast hardly caught my attention at all. Despite the email apparently referring the the biochip as the literal Mark of the Beast, I assumed it a matter of clumsy wording indicating the viewpoint that protestors were taking against the technology, certainly not the viewpoint of the manufacturers themselves. Still, I was not interested. I would not care to get the implant, nor am I horrified by the prospect of others carrying such implants in the future. The technology is not new, it is not terribly interesting, and the alleged controversy seemed a bit outdated in the social media age. In a world wherein nearly everybody willingly submits their most private information to Google and Facebook, and those companies work toward supplying face-recognition technology to public environments for the purposes of instant-tailored marketing, what does it matter if those using e-currency carry it always on their phone, a card in their pocket, or in a chip under their skin?

At some point, I was discussing current issues regarding social media and its regulation with our Ordination Director, Greg Stevens, when I remembered the BiChip email and forwarded it to him. Greg did a cursory investigation and replied to me:

As you know, Im an enthusiastic supporter of transhumanism as an overall direction and love the idea of biotech. Im looking forward to the day we have both the biotech and the AI to provide us with what I call full phenotypic freedom the ability to augment ourselves to be whatever types of creatures we want, and to interface with computer and each other in whatever way we want.

But, based on the material that I saw out there, BiChip is nothing more than a cute initial proof-of-concept in the early stages. Any details of BiChip as a company or its dealings aside, I like that promotion of the BiChip is something that can get the conversation started so that we can confront things like: what does it need to have to be useful? what are the risks and how do we build in protections against those risks from the beginning (instead of stumbling into abuses later and having to fix things after-the-fact).

I would not get the BiChip as its been described. Its simply not useful. I dont make purchases using e-currency in day-to-day life. The only reason something like ApplePay from my iPhone or Apple Watch is useful is that the software can access whatever bank account or credit card I set it up for.

Ive never seen actual whitepapers for BiChip. I saw marketing material, and marketing material is always vague. But based on what I read, BiChip was inherently crippled in that it only operated in ecurrency and was limited in what it could communicate with.

There is no revolution in this tech. The only thing exciting about it is that it was marketed as a product that might get people talking about what biotech may be able to do in the future.

This, of course, led to more in-person discussions and disagreements between Greg and I (I am far more the privacy advocate while he is more for cultivating a cultural adjustment to privacys natural diminishment through technology). Neither of us were against the concept of implants necessarily, though of course they would have to be implanted of ones own free will, without undue coercive influence. For my part, I thought that the very topic of implants might make people begin to look more clearly at the privacy they abdicate daily, finally considering regulation regarding proper usage and retention. We again began to wonder what BiChip was all about, what their event was meant to entail, and how they imagined that we would promote the event.

Over a month had passed from the original email, so I reached out to see if they were still interested in discussing details:

On Wed, 16 Oct 2019 at 07.24,

Dear Simon

We are very interested in the event.

My own position is that Data Privacy is going to necessarily be an ongoing dialogue that will always change as technology advances. I do not think we need to declare privacy dead, but I also do not think that the convenience of a microchip implant poses a deeper threat to privacy than RFID, smartphones, and social media. The question is one of responsible retention and usage of data, not a matter of withholding technologies.

Please let us know if you are still interested in our attendance and how we might help you popularize the event.

Thank you

Lucien Greaves

Spokesperson, Cofounder

The Satanic Temple

The reply came the same day:

Hi Lucien and friends

The offer is still valid and we can provide free vip tickets and free flights and hotel to Denmark for the attendees. However we prefer to have important members/board members as the priority but we can book up to 100 of these tickets.

Regarding the way you help out the event, you can come with any idea. I personally consider myself a member of the temple as i officially joined some years ago and maybe the time and money we are spending on this technology is directly a promotion for the satanist movement I guess it is time that the temple considers Bichip as a partner and help us fight together.

I recommend a direct call to Bichip president (Finn) on 004531751127 or to me 0013232180018 to speed up the process .

Best

Simon

Of course, this did not make any sense to me. An offer to fly some hundred members of The Satanic Temple (TST) to Denmark was grossly improbable even for a delusionally enthusiastic start-up. Further, the email again failed to be explicit in what Bichip would expect from me personally or TST as an organization. I lost interest entirely, but Gregs interest was piqued. Attempting a further investigation into what the whole thing was really about, Greg attempted to contact the numbers provided only to find that they were inoperative numbers. Clearly, none of this was on the level, but it was difficult to understand what exactly the scam was.

On November 08 I received a Direct Message through Twitter, which I never replied to:

I simply forgot about the whole matter.

Then, on November 16, I was tagged in a reply to a bizarre tweet by the same account that had reached out to try and confirm my presence at the international gathering.

This dialogue, I came to discover, was in reference to an article that had just been posted by biohackinfo.com claiming that authorities had raided the Bichip offices for unspecified reasons and that the event I had been invited to was therefore cancelled.

Of course, by now it was clear that the event was never intended to happen to begin with, but it was still unclear what this whole scam was meant to achieve. According to the Biohackinfo article:

Two days ago on November 14, Danish police raided the Copenhagen offices of tech company BiChip. This was three days after we broke the story about BiChips bizarre Chief Technical Officer Simon Sallienjavi, who is also the leader of a growing satanic cult that fuses devil worshiping with biohacking and transhumanism.

With all its operations shut down, BiChip has announced that all its offices are closed until December 29, and they have cancelled their much hyped November 26 event that was to be hosted at the Black Diamond building in Copenhagen. At the event, BiChip was set to unveil what it claims is a revolutionary human microchip implant that is both distance-readable and internet-connectable. Christian groups in Denmark and elsewhere in Europe were planning on protesting this event in part due to Sallienjavis notoriety in Denmark for converting Christians to satanism.

All of this was written without a single citation or hyperlink to any credible source that could confirm any of the claims made. No news articles about the police raid, no hyperlinks outside of those to other articles on the Biohackinfo page itself supporting the claims of Christian uproar, nor anything of any credible nature related to the very existence of Sallienjavi himself. The article went on to make even more extreme claims for which there are no reference anywhere outside of the Biohackinfo site:

Despite Sallienjavis eccentricities, despite his satanic cult, despite the bizarre claims he repeatedly makes in public about being the anti-Christ figure prophesied in the Bible, despite his questionable and borderline criminal activities one of which includes the disappearance of a former cult member named Anna Smolar; Sallienjavi has high level security clearance in many bureaus of the Danish government including Denmarks security services. Sallienjavi also oversees a Danish government-funded multinational called BEZH, which is the parent company of most of his numerous startups, including BiChip.

This was not a conspiracy theory. This was a conspiracy fantasy. The characters do not even exist in the real world. Searches for the story of missing cult member Anna Smolar yield nothing, and Sallienjavi is a fictional character. A significant population of people were credulous enough to believe the PizzaGate conspiracy theory which alleged that a small pizzeria in Washington, DC harbored underground tunnels where political elites engaged in human trafficking, but even that gullible audience (probably) needed at least the pizzeria in question to exist in reality before accepting claims of their covert activities.

The abrupt cancellation of the November 26 event, is going to be met with much anguish and grief from some of the people who were unexpectedly invited like American satanists from both the Church of Satan and the Satanic Temple. The latter in particular, could not wait to attend, and according to our source inside BiChip, Lucien Greaves, the founder of the Satanic Temple, which BiChip has been donating to for years, practically begged Sallienjavi to let him attend the event.

Please let us know if you are still interested in our attendance and how we might help you popularize the event, Greaves had pleaded in an email to Sallienjavi.

Although Sallienjavi wants to absorb both the Satanic Temple and the Church of Satan into his growing cult, he has little to no respect for the Temple and merely regards them as useful idiots and thralls. Sallienjavi however has respect for the Church of Satan, and BiChip had even invited Peter H. Gilmore, the current high priest of the church, to speak at the November 26 event as a secret special guest speaker. BiChip paid Gilmore with 10 bitcoin in advance, a book deal, and $15000 for his flight to Denmark. Gilmore also has an invite to the opening of Sallienjavis cults church.

The most nonsensical part about this, from my perspective, was that the Biohackinfo Twitter account reached out to me directly to taunt me with this article, thus bringing this whole farce to my attention. The claim that BiChip had heavily donated to The Satanic Temple was accompanied by a hyperlink to an image of a document with the TST letterhead at top. The text of the document stated, in embarrassingly poor English, that thanks were in order for the large donations to our church, imploring the donors, Finn and Flemming, to reach out into your network of trans humanists and pull others into the donation circle. The signature read, Kind regards, On behalf of Jacob McKelvy, T.H.

The letter, of course, is a fake, and that is why Biohackinfos enthusiasm in pointing this all out to me was perplexing. Why on earth would anybody create a story so absurd and then immediately send it to somebody who can immediately debunk it? Turns out, Jacob McKelvy is the name of some slob who pretended to be a Satanist for a while only to make a display of converting to Christianity in hopes of marketing himself to Evangelicals. He never had anything to do with TST. It is as though some fool merely Googled Satanist name and went with whatever sounded good at the time. Was Biohackinfo the gullible victim of somebody elses bizarre misinformation campaign? This seems unlikely, as in another article on the Biohackinfo site about the same fictitious Sallienjavi cult, the author writes again of my pleading to attend the international conference stating, This desperate plea by Greaves the self-professed progressive, is despite the fact that in his communication with Sallienjavi, Sallienjavi had made crazy statements to the tune of privacy is dead or privacy should be done away with. In fact, my only communication with the hoax conference (above) expressed my opposition to that perspective, a fact that Biohackinfo revealed to be fully aware of when confronted. When I replied to Biohackinfo, via public tweet, that I was confused by the extreme incompetence in their conspiracy-creation, the Twitter account responded saying, Dont lie followed by an image of my email reply to the hoax conference. And this was not an image of forwarded text from the email. It was clearly an image from the email account itself, indicating that Biohackinfo was in fact the same person behind the conference outreach email to begin with. I am hard-pressed to think of any other time I have seen something so elaborate also be so poorly-thought. This seemed to be the work of somebody who was not terribly bright, who was also quite convinced of their superior intelligence, acting in ways being mistaken for clever toward people who were being mistaken for severely mentally impaired.

Anyway, the fact that Biohackinfo was openly lying about the content of my email reply indicated that they were hardly gullible innocents being misled by another source. However, in a fit of tweets that again indicated the source to be at least partially fooled by the lies they were propagating, Biohackinfo soon began to post screenshots illustrating that they were uploading their files to Wikileaks, apparently believing that this would be of genuine concern to me

The Twitter account also began taunting the Church of Satan (which is actually little more than a Twitter account itself) with screenshots alleging to be a text correspondence with their Magus, Peter Gilmore. Gilmore, according to Biohackinfo, had accepted a speakers fee to deliver a keynote at the conference.

For their part, the Church of Satan denied that the correspondence was legitimate, and it certainly does not approach any reasonable vision of authenticity. For one thing, the correspondence suggests that monies were actually paid, which certainly never happened. Yet, here was Biohackinfo insistently sending these screenshots to the CoS Twitter, revelling in their whistleblower victory. The whole thing grew more confusing by the moment. If somebody is going to make up false accusations, why accuse somebody of something that is not even illegal, nor is it even clearly, in any way, immoral? When I asked Biohackinfo how Gilmore could have been faulted for accepting a speaking gig at the conference, if in reality he had (which he clearly did not), they replied that the effort to produce the literal so called mark of the beast was wrong.

I know that both Peter Gilmore and myself have imposter accounts manifest on a regular basis from Nigerian scammers looking to collect membership fees in our names. Is it possible that Biohackinfo was both trying to constuct an idiotic conspiracy theory about the Mark of the Beast while simultaneously being duped by an imposter Gilmore account? But what about the $15,000? Well, we dont know where the conversation went before or after that, but it looks as though the money was said to be in the mail, and the would-be scammer talking to the hoaxter may well have been skeptical, but what did they have to lose?

Interestingly, the Biohackinfo site is ostensibly a site advocating for Transhumanist agendas the technological augmentation and improvement of human biology but chip implants are a fairly mundane Transhumanist technology, and certainly not one any Transhumanist would be expected to refer to in superstitious fear-mongering language. Is it possible that Biohackinfo is a paranoid, ridiculously inept, religiously superstitious attempt to infiltrate and discredit the Transhumanist movement?

On October 22nd, 2019, the official website of the US Transhumanist Party published an article naming Biohackinfo in the creation of slanderous allegations against them:

The United States Transhumanist Party / Transhuman Party (USTP) unequivocally condemns the false, invented, and malicious allegations contained in two recent articles one by the pseudonymous authors Glyph and CyphR on the yellow-journalism Biohackinfo website, and another by the pseudonymous Nick Sobriquet, published in the Trigger Warning magazine edited by Rachel Haywire. These articles are part of a deliberate, coordinated attack on the transhumanist movement and the many decent, distinguished, accomplished, and benevolent people working within it. These articles also contain numerous outright lies and other half-truths and cherry-picked facts distorted beyond recognition.

The article reveals that the people behind Biohackinfo ran in the recent USTP Electronic Primary, speculating that it was their loss in that election that prompted them to sow chaos and exact vengeance. The Biohackinfo candidate, Rachel Haywire, apparently did not accept her second-place defeat gracefully, prompting the site to fabricate a story in which the USTP was connected to Jeffrey Epstein and intertwined in a massive web of nefarious special interests. Given that the simpletons of Biohackinfo could even make a credible run for the Transhumanist Party candidacy, my guess is that they are not very well connected with any established political players, nefarious or otherwise.

The next day, I received a Direct Message on Twitter from the legendary Sallienjavi himself:

I looked through the feed of the account. No mention of BiChip. Poor English. Various posts about President Trump that can not seem to decide whether the character of Sallienjavi is for him or against him. A few Tweets to indicate Satanism, not to mention he follows 666 accounts and has 666 embedded in his user name. Obviously, Metro.co.uk were duped by a press release when they interviewed Simon, who they then stated only uses his first name and doesnt appear on camera. The account was created in 2012. What kind of deranged fool would maintain this account for this long? Whose bitter antagonism could sustain such prolonged motivation for so long? There were no interactions on any of the posts of this alleged CEO. His followers appear to be nothing but bots and instant follow-backs. Why were these Biohackinfo clowns now messaging me from this account asking me to ignore them? My guess is that they were upset by the way I easily poked holes in their ludicrous story. At one point, the night before, they seemed to be trying to offer an olive branch so as to entice me to desist in my mockery of their infantile scheme:

Shortly thereafter, I received, also via Twitter DM, an unrelated piece of lunacy

And with that, I felt, normalcy had returned. This was a return to pure paranoia the likes of which I regularly receive without flagrant willful and grossly inept attempts at deception.

This Biohackinfo episode is easily the most elaborate and complicated display of absolute ineptitude that I have ever witnessed. I can only assume that they actually think their ploy is clever and that it will somehow prove convincing to a wider audience. They just may even be delusional enough to truly believe that their manufactured revelations will cause as they put it a geopolitical shitstorm, though to what end I can only still just speculate. One would pity them for their troubled idiocy if it were not so visibly stained with antagonistic malice. They created marketing materials for a fictitious product. They created a company and a villainous CEO. They managed to get media to pick up a press release. They manufactured a hoax conference. They put a massive amount of work into a complicated plot that was simultaneously so absurdly poorly-thought.

There is clearly more to this story for anybody who cares to look. That somebody is not presently me, but please let me know what you come up with

Please subscribe to my Patreon page:https://www.patreon.com/LucienGreaves

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The Most Elaborate Display of Ineptitude I Have Ever Witnessed: The BiChip Hoax - Patheos

Zoltan Istvan, a Leader in Science and Technology, Will Run for US President and Challenge Trump in the 2020 Republican Primaries – PR Web

Zoltan Gyurko Istvan

SAN FRANCISCO (PRWEB) November 19, 2019

Born in California, Istvan is a former journalist for National Geographic and has recently penned articles for The New York Times opinion section. In 2013, Istvan published his novel The Transhumanist Wager, which became a #1 Philosophy and Science Fiction bestseller on Amazon. The book has been compared more than 1,000 times to Ayn Rands Atlas Shrugged. Istvans most recent book of political essays titled Upgrading America was a #1 bestseller in Politics on Amazon.

Istvan has become known around the world for spearheading the multi-million person transhumanism movement, which aims to upgrade the human body with science and technology. The #1 goal of transhumanism is to overcome biological death. While still outside the political mainstream, the worlds largest companies such as Apple, Google, and Microsoft are key innovators in the transhumanist movement.

Istvan has consulted for the U.S. Navy and given speeches at conferences around the world, including for institutions such as the World Bank and the World Economic Forum. Istvan has traveled to over 100 countries and is a former director of a major wildlife organization, WildAid. He has a degree from Columbia University in Philosophy and Religion. A successful entrepreneur with multiple businesses, Istvan lives in the San Francisco Bay Area with his physician wife and two young daughters.

Istvans 20-point political platform, available on his campaign website http://www.zoltan2020.com, advances ideas that so far have been absent in the Republican primaries. Although his years as a businessman have made him fiscally conservative, Istvan supports a Universal Basic Income that is based off monetizing government resources, called a Federal Land Dividend. He proposes ending the war on drugs, making public preschool and college both free and mandatory, and licensing parents to make sure they are ready to raise children. He supports artificial wombs as a third option in the pro-life vs pro-choice debate, and would like to cut the military budget in order to create a science industrial complex in America. He aims to fight climate change with geo-engineering and end the IRS with a straightforward national sales tax. He favors nearly-open borders, tort reform, deregulation, banning private prisons, and using AI-operated drones and robots to stop mass shootings in public places and schools.

Istvan is also worried that China is beating America on the technological front in areas such as artificial intelligence, genetic editing, and neural prosthetic development. As president, he promises to get America innovating again, because once the Chinese take a lead in innovation, the United States may never get it back.

Pratik Chougule, Istvans campaign manager, says that Istvan is running as a new type of Republican politician. He expects Istvans bold ideas about the countrys future will resonate with a wide cross-section of Americans.

Istvans campaign slogan is: Upgrading America.

For more information, contact campaign manager Pratik Chougule at: pc@zoltan2020.com

To schedule an interview or talk to Mr. Istvan, email: info@zoltanistvan.com or call: 415-802-4891http://www.zoltan2020.comTwitter: @zoltan_istvan

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Zoltan Istvan, a Leader in Science and Technology, Will Run for US President and Challenge Trump in the 2020 Republican Primaries - PR Web

Vary your veggie options – The Observer

When I decided to become a vegetarian, I knew I had cut my options for accessible and convenient food in half. Most meals feature some sort of meat as the star of the dish, and it can be hard to come by a decent vegetarian option, especially when youre in a rush. And while CWU does have a few options for vegetarian and vegan students, if were being honest, they could be doing a lot better.

According to Forbes, 10% of Americans aged 18 to 29 do not eat meat, with 7% being vegetarian and 3% who are vegan. This is much higher than any of the older age ranges surveyed and shows a trend of college-aged Americans eating less meat. With vegetarianism and veganism on the rise, options on college campuses should reflect the growing demand.

As a senior who lives off campus, Ill admit that I dont eat at the SURC very often. I cant recall many vegetarian options in the dining hall when I was a freshman, but I know that dining has recently expanded their menu to include more meatless dishes. Lately, my experience with vegetarian options at CWU has been grab-and-go options from the Bistro or C-Store. Here, I can find an overpriced bowl of chopped fruit; a protein box with nuts, hummus and veggies; and salads, salads and more salads. While its great that these options are available for students who dont eat meat, eating the same thing over and over can get pretty boring.

With limited meatless options to pick from, I should at least be able to expect my vegetarian meal to actually be vegetarian. Just last week, I picked up a grab-and-go salad from the bistro, clearly marked with a V indicating that it was vegetarian. As I sat down, open my salad and pour on the dressing that was included, I decided to take a peek at the ingredients contained in the dressing. About halfway down the list, I see it: anchovy paste. For me, this was little more than an annoyance. Some people, though, may be allergic or intolerant to an ingredient like anchovies. It can be easy to overlook a minor ingredient like that in a dressing or a side component of the meal. But had I known it wasnt vegetarian, I wouldnt have wasted $6 on the salad in the first place.

I think its awesome that vegetarian options are there, and compared to some other colleges, CWU has plenty to offer in that area. I just think that options could be expanded to include other types of dishes. Instead of a bland salad or mediterranean-style wrap, why not offer something more interesting and flavorful, like curry or a vegan pad thai? There are lots of cultures that have dishes that revolve around plant-based diets, such as Indian, Ethiopian and Thai cuisines. Adding dishes like these would not only bring more flavor to the vegetarian menu at CWU, but also deliver a taste of culture and diversity as well.

Other than the lack of variety, the problem I have with vegetarian options on campus is the lack of protein. Often, when I need to grab a quick bite, I have to opt for some sort of fruit or veggie-based snack with a low amount of protein. Aside from the protein box, the options presented at grab-and-go locations on campus arent the most protein-packed meals. It would be cool to have more meal options that feature beans, chickpeas or even meat alternatives, such as Beyond Meat, as a plant-based protein source.

In the future, as more students start eating less meat and the demand for meatless meals goes up, Im sure options for vegan and vegetarian students will expand. But until then, Ill keep bringing my lunch from home.

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Vary your veggie options - The Observer

Hosting vegetarian guests? Make this mushroom dish that even turkey-lovers want to try – INFORUM

The rise of vegetarianism over the past decade means that its likely your guest list will include at least one or more folks who prefer a meatless Thanksgiving. While many vegetarian guests will tell you not to go to any extra trouble, and that theyre happy to graze from the standard variety of vegetable side dishes, we worry that the lack of protein means that they will leave our table still hungry. This simply is not allowed in our food-friendly home, especially on Thanksgiving.

It doesnt take much extra effort to provide a plant-based protein alternative for your veggie-loving guests, and these Caprese-Stuffed Portobello Mushrooms are hearty, delicious and easy to prepare, even in the midst of pre-feast kitchen chaos.

Low in fat, calories and sodium, nutrient-dense portobello mushrooms are a good source of protein, fiber and folate to ensure a full belly, as well as a host of vitamins and minerals believed to help fight cancer, boost the immune system and decrease inflammation. Portobello mushrooms have a wonderful meaty quality in both texture and taste, which makes them popular with vegetarians and carnivores alike.

For this simple dish, youll need four large portobello mushrooms, which are commonly sold in packs of two in most supermarkets. To prepare the mushrooms, remove any remaining stems as well as the dark brown gills to clear space for the caprese stuffing. The gills can be easily removed by gently scraping them with the edge of a spoon.

The gills of portobello mushrooms can be scraped out with a spoon to make room for the caprese stuffing. Michael Vosburg / Forum Photo Editor

Once the inside is prepped, use a damp paper towel to wipe away any dirt from the top and inside of each mushroom. Next, brush each mushroom with a mixture of extra-virgin olive oil, minced garlic, salt and pepper and bake at 400 degrees until soft, about 10 minutes.

Once theyre soft, remove them from the oven and use a paper towel to absorb the excess moisture released in each mushroom. If your available oven time is limited on turkey day, you can refrigerate the mushrooms at this stage for up to one day.

The caprese stuffing is inspired by our wonderful time in Sicily this past summer, which was filled with a bounty of fresh mozzarella cheese and tomatoes. I use fresh mozzarella balls, either pre-marinated or plain, and my favorite variety of flavor bomb cherry tomatoes. Both products can be found in most supermarkets and big-box stores in the Fargo-Moorhead area.

A caprese filling of fresh tomatoes and mozzarella is used to stuff portobello mushrooms. Michael Vosburg / Forum Photo Editor

To flavor the caprese mixture, I use extra-virgin olive oil, a splash of red wine vinegar, a pinch of crushed red pepper flakes and a dash of Sicilian herb seasoning blend (any blend of dried oregano, basil and parsley will do). Each mushroom cap is stuffed with the caprese mixture and baked until the cheese is melted and bubbly, and the tomatoes just begin to blister, about 12 to 15 minutes.

For extra Italian flavor and a pop of color, garnish the mushrooms with thin strips of fresh basil and a drizzle of either balsamic reduction or basil pesto.

With their big flavor, bold colors and high nutrition, these Caprese-Stuffed Portobello Mushrooms are the perfect vegetarian dish for the upcoming holiday season. But, be warned: theyre so attractive and delicious that your turkey-loving guests will probably want a taste, too.

ARCHIVE: Read more Lost Italian columns and recipes

Serves: 4

Ingredients:

4 portobello mushrooms caps, washed and thoroughly dried with paper towel (if purchasing whole, remove the stems and gills)

cup extra-virgin olive oil or canola oil, divided

1 clove garlic, minced

teaspoon kosher salt

teaspoon black pepper

teaspoon red wine vinegar

teaspoon Sicilian or Italian herb seasoning (blend of dried herbs like oregano, parsley and basil)

Pinch of crushed red pepper flakes

1 cup cherry tomatoes, halved

cup fresh mozzarella balls, halved (if using a log of mozzarella, cut into -inch pieces)

2 tablespoons fresh basil, sliced into thin strips (chiffonade), about 4 large leaves

For garnish: Balsamic reduction or basil pesto (optional)

Directions:

Preheat oven to 400 degrees. Line a baking sheet with parchment paper or foil; set aside.

In a small bowl, combine 2 tablespoons of oil with the minced garlic, salt and black pepper. Brush each mushroom all over with the oil mixture, then place on the prepared baking sheet, top side down.

Bake until the mushrooms are soft to the touch, about 9 to 10 minutes. Use a paper towel to soak up the excess moisture inside the mushrooms. The mushrooms can be used immediately or refrigerated at this stage for up to 1 day until ready to finish baking. Bring to room temperature before baking.

As the mushrooms bake: In a medium bowl, use a whisk to combine the remaining 2 tablespoons of oil with the vinegar, herb seasoning and red pepper flakes. Add the tomatoes and mozzarella and gently toss to combine. Taste and add salt and pepper as desired (I use teaspoon of each).

Once the mushrooms are baked until softened, and wiped free of excess moisture, fill the inside of each with the caprese mixture. Return mushrooms to the baking sheet and bake until the tomatoes begin to blister and the cheese is melted and bubbly, about 12 to 15 minutes.

Remove from oven and transfer mushrooms to serving plates or a platter. Generously sprinkle each mushroom with the chopped basil and garnish with a drizzle of reduced balsamic vinegar or basil pesto.

This week in...

Home with the Lost Italian is a weekly column written by Sarah Nasello featuring recipes by her husband, Tony Nasello. The couple owned Sarellos in Moorhead and lives in Fargo with their son, Giovanni. Readers can reach them at sarahnasello@gmail.com.

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Hosting vegetarian guests? Make this mushroom dish that even turkey-lovers want to try - INFORUM

LETTER TO THE EDITOR: A vegetarian diet is a viable choice – BCLocalNews

To the editor,

Re: Its a bit late to demand total plant consumption, Nov. 5.

The columnist asks how veganism would contribute to ecological well-being of humans and other animal species and then concedes that it would achieve immense savings in health costs and reduction in greenhouse gases.

In the north, or on land suitable for pasture but not for crops, I can understand raising animals as a local option. Here in the developed world we tend to build residential suburbs on fine farm land. But to state that shifting to plant diets doesnt take into account global impacts or historical realities sounds very much like the rhetoric of the global corporate capitalism that she decries.

Plant diets can support larger populations than animal diets based on plant inputs. The vegetarian philosophies of Pythagoras of Samos and Gautama Buddha are more than 2,500 years old, and a Scientific American article points to evidence that our ancestors have been primarily vegetarian for 30 million years.

We know that business and political interests prop each other up. Far from being a large-scale action that can only be effected by governments, vegetarianism is a personal decision that can be put into practice every day, and its as down-to-earth as backyard gardening. Anywhere in urban Canada (and especially on Vancouver Island and the Lower Mainland) its easy to find the ingredients for a meal of vegetables made with love.

As Jonathan Safran Foer writes, Choosing leaf or flesh, factory farm or family farm, does not in itself change the world, but teaching ourselves, our children, our local communities and our nation to choose conscience over ease can.

If humans deserve justice, then so do animals.

Ian Poole, Nanaimo

OPINION: Its a bit late to demand total plant consumption

RELATED: New Canada Food Guide nixes portion sizes, promotes plant-based proteins


The views and opinions expressed in this letter to the editor are those of the writer and do not reflect the views of Black Press or the Nanaimo News Bulletin. If you have a different view, we encourage you to write to us or contribute to the discussion below.

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LETTER TO THE EDITOR: A vegetarian diet is a viable choice - BCLocalNews

Testosterone Replacement Therapy Market Report 2019 : Global Analysis and Forecast by 2027 – Eastlake Times

The Testosterone Replacement Therapy Market report is a thorough analysis of the market that offers a detailed assessment of the market situation for the forecast period 2019-2027. The report systematically explains market trends, growth opportunities, challenges, drivers, and other factors impacting the Testosterone Replacement Therapy market. The key focus of the report assists business owners in understanding the market in terms of its segmentation, regional distribution, and influential trends. The report will provide readers a comprehensive analysis of the Testosterone Replacement Therapy market with a broad perspective into the global economy and competitive landscape. The report contains first-hand data of market trends, obtained through rigorous research that can transform the arc of your Business.

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The Testosterone Replacement Therapy report offers the plus points as well as weaknesses of the established market players. It analyses numerous features of the global Testosterone Replacement Therapy market such as demand, drivers, challenges, and options. The report appraises the influence of these aspects on each market region during the estimated time. It presents the value chain analysis together with vendor list and highlights the present market situation between consumer and supplier.

In order to give the users of this report a comprehensive view of the Testosterone Replacement Therapy market, we have included a competitive landscape and an analysis of Porters Five Forces model for the market. The study encompasses a market attractiveness analysis, wherein all the segments are benchmarked based on their market size, growth rate, and general attractiveness.

The years considered to estimate the Insights of Testosterone Replacement Therapy Market are as follows:-

History Year: 2014-2018

Base Year: 2018

Estimated Year: 2019

Forecast Year: 2019 to 2027

Key Highlights of Global Testosterone Replacement Therapy Market Report 2019:

Snaps From the Testosterone Replacement Therapy Report / TOC :

1 Market Overview

1.1 Testosterone Replacement Therapy Introduction

1.2 Market Analysis by Type

1.3 Market Analysis by Applications

1.4 Market Analysis by Regions

North America (USA, Canada and Mexico)

Europe (Germany, France, UK, Russia and Italy)

Asia-Pacific (China, Japan, Korea, India and Southeast Asia)

South America, Middle East and Africa

1.5 Market Dynamics

2 Manufacturers Profiles

3 Global Testosterone Replacement Therapy Market Competition, by Manufacturer

4 Global Testosterone Replacement Therapy Market Analysis by Regions

4.1 Global Testosterone Replacement Therapy Sales, Revenue and Market Share by Regions

(continued)

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10 Global Testosterone Replacement Therapy Market Segment by Type

11 Global Testosterone Replacement Therapy Market Segment by Application

12 Testosterone Replacement Therapy Market Forecast (2019-2027)

13 Sales Channel, Distributors, Traders and Dealers

14 Research Findings and Conclusion

Testosterone Replacement Therapy market will prove as a valuable source of guidance for professional clients like Tier 1, Tier 2, Tier 3 level managers, CEOs, CMOs, as well as interested individual readers across the world. Vendor Landscape provide acts as key development and focus of above professional with common aim to lead the way of Testosterone Replacement Therapy market Worldwide.

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Testosterone Replacement Therapy Market Report 2019 : Global Analysis and Forecast by 2027 - Eastlake Times

SHAREHOLDER ALERT: Pomerantz Law Firm Reminds Shareholders with Losses on their Investment in Lipocine Inc. of Class Action Lawsuit and Upcoming…

NEW YORK, Nov. 20, 2019 (GLOBE NEWSWIRE) -- Pomerantz LLP announce that a class action lawsuit has been filed against Lipocine Inc. (Lipocine or the Company) (NASDAQ:LPCN) and certain of its officers. The class action, filed in United States District Court, for the District of Utah, and docketed under 19-cv-00906, is on behalf of a class consisting of investors who purchased or otherwise acquired Lipocine securities between March 27, 2019, and November 8, 2019, both dates inclusive (the Class Period), seeking to recover damages caused by Defendants violations of the federal securities laws and to pursue remedies under Sections 10(b) and 20(a) of the Securities Exchange Act of 1934 (the Exchange Act) and Rule 10b-5 promulgated thereunder, against the Company and certain of its top officials.

If you are a shareholder who purchased Lipocine common shares within the Class Period, you have until January 14, 2020, to ask the Court to appoint you as Lead Plaintiff for the class. A copy of the Complaint can be obtained at http://www.pomerantzlaw.com. To discuss this action, contact Robert S. Willoughby at rswilloughby@pomlaw.com or 888.476.6529 (or 888.4-POMLAW), toll-free, Ext. 9980. Those who inquire by e-mail are encouraged to include their mailing address, telephone number, and number of shares purchased.

[Click here for information about joining the class action]

Lipocine is a specialty pharmaceutical company that focuses on the development of pharmaceutical products in the area of mens and womens health. The Companys primary development programs are based on oral delivery solutions for poorly bioavailable drugs. The Company has a portfolio of product candidates purportedly designed to produce pharmacokinetic characteristics and facilitate lower dosing requirements, bypass first-pass metabolism in certain cases, reduce side effects, and eliminate gastrointestinal interactions that limit bioavailability.

Lipocines lead product candidate is TLANDO (LPCN 1021), an oral testosterone replacement therapy. The Company has previously submitted New Drug Applications (NDA) for TLANDO twice and, both times, received Complete Response Letters (CRL) from the U.S. Food and Drug Administration (FDA) rejecting the NDAs. The Company received the first CRL in June 2016 and the second in May 2018.

On March 27, 2019, during pre-market hours, Lipocine issued a press release announcing new topline results from a study evaluating TLANDOs effects on blood pressure (one issue cited by the FDA in a prior CRL rejecting TLANDOs NDA), as well as the Companys intention to refile the NDA for TLANDO in the second quarter of 2019 (the March 2019 Press Release).

The Complaint alleges that throughout the Class Period, Defendants made materially false and misleading statements regarding the Companys business, operational and compliance policies. Specifically, Defendants made false and/or misleading statements and/or failed to disclose that: (i) the results from Lipocines clinical studies of TLANDO were insufficient to demonstrate the drugs efficacy; (ii) accordingly, Lipocines third NDA for TLANDO was highly likely to be found deficient by the FDA; and (iii) as a result, the Companys public statements were materially false and misleading at all relevant times.

On November 11, 2019, Lipocine issued a press release announcing receipt of a CRL from the FDA regarding its NDA for TLANDO. In the press release, Lipocine advised investors that the FDA had again rejected the NDA for TLANDOthis time because an efficacy trial had not met three of its secondary endpoints.

On this news, Lipocines stock price fell $1.93 per share, or 70.7%, to close at $0.80 per share on November 11, 2019.

The Pomerantz Firm, with offices in New York, Chicago, Los Angeles, and Paris is acknowledged as one of the premier firms in the areas of corporate, securities, and antitrust class litigation. Founded by the late Abraham L. Pomerantz, known as the dean of the class action bar, the Pomerantz Firm pioneered the field of securities class actions. Today, more than 80 years later, the Pomerantz Firm continues in the tradition he established, fighting for the rights of the victims of securities fraud, breaches of fiduciary duty, and corporate misconduct. The Firm has recovered numerous multimillion-dollar damages awards on behalf of class members. See http://www.pomerantzlaw.com.

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SHAREHOLDER ALERT: Pomerantz Law Firm Reminds Shareholders with Losses on their Investment in Lipocine Inc. of Class Action Lawsuit and Upcoming...

INVESTOR ALERT – Lipocine Inc. (LPCN) – Bronstein, Gewirtz & Grossman, LLC Notifies Investors of Class Action and Lead Deadline: January 14, 2020…

NEW YORK, NY / ACCESSWIRE / November 20, 2019 / Bronstein, Gewirtz & Grossman, LLC notifies investors that a class action lawsuit has been filed against Lipocine Inc. ("Lipocine" or the "Company") (LPCN) and certain of its officers, on behalf of shareholders who purchased Lipocine securities purchased between March 27, 2019, and November 8, 2019, both dates inclusive. Such investors are encouraged to join this case by visiting the firm's site:www.bgandg.com/lpcn.

This class action seeks to recover damages against Defendants for alleged violations of the federal securities laws under the Securities Exchange Act of 1934.

The complaint alleges that throughout the Class Period, defendants made false and/or misleading statements and/or failed to disclose that: (1) the results from Lipocine's clinical studies of TLANDO were insufficient to demonstrate the drug's efficacy; (2) accordingly, Lipocine's third NDA for TLANDO was highly likely to be found deficient by the FDA; and (3) as a result, the Company's public statements were materially false and misleading at all relevant times.

On November 11, 2019, Lipocine announced receipt of a Complete Response Letter ("CRL") from the U.S. Food and Drug Administration regarding its New Drug Application for TLANDO, Lipocine's product candidate for testosterone replacement therapy. Lipocine advised investors, inter alia, that "[t]he CRL identified one deficiency stating the efficacy trial did not meet the three secondary endpoints for maximal testosterone concentrations." On this news, Lipocine's stock price fell sharply during intraday trading on November 11, 2019.

If you wish to review a copy of the Complaint you can visit the firm's site: http://www.bgandg.com/lpcn or you may contact Peretz Bronstein, Esq. or his Investor Relations Analyst, Yael Hurwitz of Bronstein, Gewirtz & Grossman, LLC at 212-697-6484. If you suffered a loss in Lipocine you have until January 14, 2020 to request that the Court appoint you as lead plaintiff. A lead plaintiff acts on behalf of all other class members in directing the litigation. The lead plaintiff can select a law firm of its choice. Your ability to share in any recovery doesn't require that you serve as a lead plaintiff.

Bronstein, Gewirtz & Grossman, LLC is a corporate litigation boutique. Our primary expertise is the aggressive pursuit of litigation claims on behalf of our clients. In addition to representing institutions and other investor plaintiffs in class action security litigation, the firm's expertise includes general corporate and commercial litigation, as well as securities arbitration. Attorney advertising. Prior results do not guarantee similar outcomes.

Contact:

Bronstein, Gewirtz & Grossman, LLCPeretz Bronstein or Yael Hurwitz

212-697-6484 | info@bgandg.com

SOURCE: Bronstein, Gewirtz & Grossman, LLC

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INVESTOR ALERT - Lipocine Inc. (LPCN) - Bronstein, Gewirtz & Grossman, LLC Notifies Investors of Class Action and Lead Deadline: January 14, 2020...

Global Testosterone Replacement Therapy Market Forecast, by regions, type and application, with sales and revenue, from 2019 to 2024. – Med News…

According to a latest report published by Global Marketers Biz named as Testosterone Replacement Therapy Market offers data for the forecast period 2019-2024. A comprehensive research updates and data which includes following key aspects for the global Testosterone Replacement Therapy Market in terms of volume and revenue Visitor Demographics, Facility Size, Demand & Growth Opportunities, Global Industry Forecast Analysis and Revenue Source.

The Testosterone Replacement Therapy Market report offers in-depth analysis and insights into developments impacting businesses and enterprises on global & regional level. A detailed breakdown of key trends, drivers, restraints, and opportunities influencing revenue growth is presented in this research report. This study focuses on the global Testosterone Replacement Therapy market by share, volume, value, and regional appearance along with the types and applications.

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GelsInjectionsPatchesOther

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Nanomedicine Market Healthy Pace throughout the Forecast by 2023 – Crypto News Byte

Overview:

Nanomedicine is an offshoot of nanotechnology, and refers to highly-specific medical intervention at the molecular scale for curing diseases or repairing damaged tissues. Nanomedicine uses nano-sized tools for the diagnosis, prevention and treatment of disease, and to gain increased understanding of the complex underlying pathophysiology of the disease. It involves three nanotechnology areas of diagnosis, imaging agents, and drug delivery with nanoparticles in the 11,000 nm range, biochips, and polymer therapeutics.

Get Sample Copy Of The Report@ https://www.trendsmarketresearch.com/report/sample/9807

Majority of nanomedicines prescribedcurrently, allow oral drug delivery and its demand is increasing significantly. Although these nanovectors are designed to translocate across the gastrointestinal tract, lung, and bloodbrain barrier, the amount of drug transferred to the organ is lower than 1%; therefore improvements are challenging. Nanomedicines are designed to maximize the benefit/risk ratio, and their toxicity must be evaluated not only by sufficiently long term in vitro and in vivo studies, but also pass multiple clinical studies.

Market Analysis:

The Global Nanomedicine Market is estimated to witness a CAGR of 17.1% during the forecast period 20172023. The nanomedicine market is analyzed based on two segments therapeutic applications and regions.

The major drivers of the nanomedicine market include its application in various therapeutic areas, increasing R&D studies about nanorobots in this segment, and significant investments in clinical trials by the government as well as private sector. The Oncology segment is the major therapeutic area for nanomedicine application, which comprised more than 35% of the total market share in 2016. A major focus in this segment is expected to drive the growth of the nanomedicine market in the future.

Regional Analysis:

The regions covered in the report are the Americas, Europe, Asia Pacific, and Rest of the World (ROW). The Americas is set to be the leading region for the nanomedicine market growth followed by Europe. The Asia Pacific and ROW are set to be the emerging regions. Japan is set to be the most attractive destination and in Africa, the popularity and the usage of various nano-drugs are expected to increase in the coming years. The major countries covered in this report are the US, Germany, Japan, and Others.

Therapeutic Application Analysis:

Nanomedicines are used as fluorescent markers for diagnostic and screening purposes. Moreover, nanomedicines are introducing new therapeutic opportunities for a large number of agents that cannot be used effectively as conventional oral formulations due to poor bioavailability. The therapeutic areas for nanomedicine application are Oncology, Cardiovascular, Neurology, Anti-inflammatory, Anti-infectives, and various other areas. Globally, the industry players are focusing significantly on R&D to gain approval for various clinical trials for future nano-drugs to be commercially available in the market. The FDA should be relatively prepared for some of the earliest and most basic applications of nanomedicine in areas such as gene therapy and tissue engineering. The more advanced applications of nanomedicine will pose unique challenges in terms of classification and maintenance of scientific expertise.

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Key Players:

Merck & Co. Inc., Hoffmann-La Roche Ltd., Gilead Sciences Inc., Novartis AG, Amgen Inc., Pfizer Inc., Eli Lilly and Company, Sanofi, Nanobiotix SA, UCB SA and other predominate & niche players.

Competitive Analysis:

At present, the nanomedicine market is at a nascent stage but, a lot of new players are entering the market as it holds huge business opportunities. Especially, big players along with the collaboration with other SMBs for clinical trials of nanoparticles and compounds are coming with new commercial targeted drugs in the market and they are expecting a double-digit growth in the upcoming years. Significant investments in R&D in this market are expected to increase and collaborations, merger & acquisition activities are expected to continue.

Benefits:

The report provides complete details about the usage and adoption rate of nanomedicines in various therapeutic verticals and regions. With that, key stakeholders can know about the major trends, drivers, investments, vertical players initiatives, government initiatives towards the nanomedicine adoption in the upcoming years along with the details of commercial drugs available in the market. Moreover, the report provides details about the major challenges that are going to impact on the market growth. Additionally, the report gives the complete details about the key business opportunities to key stakeholders to expand their business and capture the revenue in the specific verticals to analyze before investing or expanding the business in this market.

Report Analysis@ https://www.trendsmarketresearch.com/report/analysis/IR/nanomedicine-market

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Nanomedicine Market Healthy Pace throughout the Forecast by 2023 - Crypto News Byte

Healthcare Nanotechnology (Nanomedicine) Market 2019 Industry Outlook, Comprehensive Insights, Growth and Forecast 2025 – WindStreetz

The company provides a detailed analysis of the market and future aspects of the Healthcare Nanotechnology (Nanomedicine) Market. It focuses on critical and critical data that makes it a very important tool for research, experts, analysts, and managers to achieve ready-to-access analysis. The report provides an inclusive analysis of the Healthcare Nanotechnology (Nanomedicine) market size forecast from 2018-2025.

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The report embraces the complete information of the key players involved in the worldwide Healthcare Nanotechnology (Nanomedicine) market. In addition, it provides its market share by various regions with the company and product introduction and their position in the Healthcare Nanotechnology (Nanomedicine) market. In addition, the report takes into account recent marketing developments as well as their marketing strategies along with an overall business overview. In addition, the report covers market growth factors and restraints of this market.

Prominent players of Healthcare Nanotechnology (Nanomedicine) market:

Product Type Coverage (Market Size & Forecast, Major Company of Product Type etc.):

Application Coverage (Market Size & Forecast, Different Demand Market by Region, Main Consumer Profile etc.):

Regional Segmentation for Healthcare Nanotechnology (Nanomedicine) market:

There are 10 chapters to put on view for Healthcare Nanotechnology (Nanomedicine) market:

Chapter 1: Consumption by Regions

Chapter 2: Production, By Types, Revenue and Market share by Types

Chapter 3: Consumption, By Applications, Market share (%) and Growth Rate by Applications

Chapter 4: Complete profiling and analysis of Manufacturers

Chapter 5: Manufacturing cost analysis, Raw materials analysis, Region-wise manufacturing expenses

Chapter 6: Industrial Chain, Sourcing Strategy and Downstream Buyers

Chapter 7: Marketing Strategy Analysis, Distributors/Traders

Chapter8: Market Effect Factors Analysis

Chapter9: Market Forecast

Chapter 10: Healthcare Nanotechnology (Nanomedicine) Research Findings and Conclusion, Appendix, methodology and data source

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Gareth Jenkinson is a journalist and radio presenter based in Durban, South Africa. When hes not talking about sport on the airwaves - hes got his eye on the Cryptocurrency market.

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Healthcare Nanotechnology (Nanomedicine) Market 2019 Industry Outlook, Comprehensive Insights, Growth and Forecast 2025 - WindStreetz

Bankrupt biopharmas are rare. 2019 has some worried that’s changing. – BioPharma Dive

Editors note: This is part of a series about bankruptcy in the biopharma industry. Click here to see a running list of 2019 biopharma bankruptcies, and click here to see 31 biopharmas at high risk of bankruptcy for 2020.

Six years ago, Bind Therapeutics was flying high, with little idea how hard it would soon crash.

Headed into a public stock offering in 2013, the biotech, founded by top MIT and Harvard researchers, generated buzz with its lofty scientific ambitions. Company executives believed its nanomedicine platform, while only through Phase 1 tests, represented the next advance in cancer therapies.

Those dreams came undone within three years. As its experimental therapies struggled in clinical testing, Bind was punished by the market, and debt repayments forced the company into bankruptcy in 2016.

Bind may be a cautionary story in todays life sciences ecosystem, one that features biotechs going public at earlier stages and with heightened ambitions.

While bankruptcy is a rare outcome for biopharmas, 2019 has bucked that trend with an uptick in Chapter 11 filings. Eleven companies have declared bankruptcy so far this year, compared to an average of four per year during the past decade, according to a review of data tracked by the firm BankruptcyData.

That increase may forewarn of more companies falling to zero, industry experts said in interviews with BioPharma Dive, especially at a time of rising legal and political headwinds for the sector. After a decade of booming growth, the ballooning ranks of newly public biotechs may struggle to withstand market pressures.

I think theres a turning point now, said Andrew Hirsch, the former CEO of Bind, in an interview. I think its not sustainable.

Hirsch highlighted the rising prominence of early-stage platform companies, like Bind, going public in greater numbers and at larger valuations. That can bring steeper downside, he warned.

Things arent always going to work the first time, thats just the rule in this industry. A lot of times, companies are valued for perfection, said Hirsch, now Agios Pharmaceuticals chief financial officer.

If they are lucky and it works, thats great. But if you have a setback because youre doing novel things, the public markets can be a cruel place to be.

Biotech vastly outperformed the broader stock market over the past decade, and a steady inflow of capital supported more companies going public at rich valuations.

But those tides have turned. A leading biotech index has fallen more than 15% since peaking in the summer of last year, while the S&P 500 has ticked up nearly 13% in the same timeframe. The capital required for funding biopharmas ambitions is leaving too, with one Wall Street firm calculating $8.7 billion in net capital outflows this year rivaling a stretch in late 2015 and early 2016.

After years of outperformance, biotech has lagged the market for the past year

Price per share of a leading biotech index (XBI) and the S&P 500 (SPX) from January 2018 to October 2019 (indexed)

The base value of the index is trading value on Jan. 2, 2018.

Nami Sumida/BioPharma Dive

Investor anxiety is rising at a time when more companies are fighting for funding than in past decades. Evercore ISI analyst Josh Schimmer said this year hes noticed a marked shift in investor attitudes.

When they stumble, the markets are more unforgiving than ever, Schimmer said in an interview. They arent given second chances the way they used to be given. That may be a factor that does lead to a higher rate of bankruptcies.

And small biotechs arent the only ones facing elevated bankruptcy risk. The weight of thousands of lawsuits related to opioid marketing has already taken down Purdue Pharma and Insys Therapeutics. Several others, like Teva Pharmaceutical, Mallinckrodt and Amneal, are at risk of joining them.

The legal uncertainty has made these companies perceived as uninvestable, SVB Leerink analyst Ami Fadia said in an interview. Additionally, many of these pharmas are highly leveraged and face issues in generating cash going forward, she added.

Its pretty obvious that some of these companies are at high risk of bankruptcy, said Fadia, who covers several of these drugmakers including Mallinckrodt and Amneal.

To be sure, the effect of opioid liabilities is constrained to a comparatively small set of companies. But heading into an election year with drug pricing as a top issue, worries about capital fleeing the industry and a legal crackdown on opioid makers could be exacerbated by political threats as well.

Industry lobbyists have blasted HR3, the leading Democratic drug pricing proposal, saying it would trigger a nuclear winter by eroding the upside of biopharmas high-risk, high-reward investment premise.

If HR3 becomes law, it is lights out for a lot of very small biotech companies that are pre-revenue and depend on attracting capital, PhRMA CEO Stephen Ubl said at a recent media briefing.

Industry-specific concerns, of course, come against the backdrop of fears of a broader economic slowdown. Financial analysts have flagged recession signals in the U.S., which, if materialized, would further squeeze the industry.

It may be coming, in which capital itself is scarcer for companies, said Bob Eisenbach, a lawyer at Cooley specializing in bankruptcies. And when that happens, it puts pressure even on good companies.

Biopharmas are structured to avoid bankruptcies. Pre-revenue companies typically carry little debt and have little to restructure through a bankruptcy court if their pipeline fizzles.

Privately held biotechs that suffer clinical failures can also avoid bankruptcy by having their financial backers buy them out, saving face for those venture capitalists.

It just disappears into this great maw of the biotech universe, said Kevin Kinsella, a venture capitalist and founder of Avalon Ventures, referring to distressed biotechs in an interview.

Having launched more than 100 biopharmas, including prominent names like Vertex, Neurocrine and Onyx, Kinsella said hes been lucky enough to avoid getting entangled in any bankruptcies.

Someone absolutely failing, shutting the doors and turning off the lights, you dont really see that a lot in our industry, he said.

Drug companies, both young and old, derive value from ideas and hope more than tangible assets or resources. Just last year, early-stage platform companies like Moderna Therapeutics and Rubius Therapeutics went public with multi-billion dollar valuations despite lacking profits and significant clinical data.

But investor attitudes appear to have shifted. Rubius stock, for instance, has dropped more than 70% since its IPO. While up this month, shares in Moderna are 30% off their 52-week high in May.

Speaking generally about platform companies, Binds former CEO said market sentiment has turned.

Investors have lost their appetite for companies going public with preclinical data, Hirsch said.

Youre probably going to see more of these situations going forward, where a company is preclinical, went public and is left on their own and has to raise additional money from the public markets and they flounder.

Yet even floundering biotechs can persist for years, even decades. Long-standing industry veterans like Xoma, Novavax and Geron have survived in as-yet fruitless searches for their first drugs, suffering clinical failures along the way. Despite accumulated deficits exceeding $1 billion, these companies can find the necessary capital to keep chugging along.

Theres always someone else whos willing to bet the next discovery is around the corner, or the next asset, or if we get this clinical trial enrolled and finished, all will be good, Kinsella said. Theres always hope.

Besides selling hope, biopharmas, like all businesses, have practical options to stave off bankruptcy. Restructuring and raising cash are the main focuses, turnaround experts said.

Corporate restructurings typically shrink the business, either by laying off employees, selling assets or killing off R&D projects. Raising capital can include licensing rights to experimental therapies, taking on debt or tapping the public markets for secondary stock offerings.

If those options are exhausted, M&A can be another way out for shareholders. Firms like Deerfield Management, Hercules Capital and Highbridge Capital Management often aid distressed biotechs in such endeavours.

Deerfield, for instance, reached deals to finance R&D costs for Dynavax and helped fund Melinta Therapeutics acquisition of an infectious disease business.

A last resort can be merging with another struggling biotech, or becoming the shell in a reverse merger for another company seeking an easy path to a public listing.

Both happened in just the past few weeks. Foamix Pharmaceuticals and Menlo Therapeutics merged into one dermatology company, while NewLink Genetics was the shell through which Lumos Pharma joined public markets.

These strategies act as moats that insulate a high-risk industry from bankruptcy. In recent years, they have worked tremendously well. Among the 333 biopharmas that have gone public since 2012, just 3% filed for bankruptcy while 6% became reverse merger shells and 10% exited via M&A, according to data tracked by Evercore ISI.

But with 2019 looking shaky for biopharma, some have begun to wonder how markets will respond.

The last few years have featured record levels of capital raising, according to the investment bank Jefferies, which tallied 100 initial public offerings and 270 follow-on raises in 2018 and 2019 that drummed up tens of billions in cash.

At the same time, the number of public small and mid-sized biotechs has doubled in the past decade. There arent just more of these smaller firms; they also are worth more and consume more capital on average. From 2010 to present, these companies have seen their typical market values double, R&D budgets triple and cash burn rates quadruple, Jefferies found.

The annual burn rate for these biotechs, which includes market values from $200 million to $5 billion, has increased from $20 million to $80 million. Jefferies analyst Michael Yee credited that to free-flowing capital, more platform companies and an arms race in oncology.

Biotechs impressive market performance has made that possible. A leading biotech index, for instance, outperformed the S&P 500 by 30% since the market bottomed out in March 2009.

But of late, biotech has struggled, creating a tougher environment to raise cash.

The question is whether this is sustainable if market and macro conditions get tougher and political uncertainty gets more obvious, forcing companies to tighten their belts to ride out 2020, Yee wrote.

2019 has brought an uptick in industry bankruptcy filings

Credit: Data from Bankruptcy Data

Conditions have clearly worsened by some metrics, such as the amount of money invested in healthcare- or biotech-dedicated funds. Data tracked by a Piper Jaffray found $8.7 billion in investment has left such funds in 2019. Ten of the past 12 weeks have registered net capital outflows, a streak a Piper Jaffray analyst called seemingly the new normal.

Billions of dollars flowed out of biotech in 2015 and 2016, too, at a time when many biotech shares were falling and the prospect of a Hillary Clinton presidency had raised investor fears on drug pricing.

Biotech weathered that storm, with few companies entering bankruptcy, and has grown since. Going forward, a critical question will be gauging whether the sector is on a new trajectory or if it will emerge from this period relatively unscathed.

Getting investor attention is harder than ever to begin with, said Evercores Schimmer. For a company that has faltered, even if they are doing the right thing, its a struggle.

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Bankrupt biopharmas are rare. 2019 has some worried that's changing. - BioPharma Dive

‘Bad cholesterol’ is only as unhealthy as its composition: Research demonstrates that current guidelines for diagnosing risk are ‘dangerously…

New research at Ohio University shows that a particular subclass of low-density lipoproteins (LDL), also known as bad cholesterol, is a much better predictor of potential heart attacks than the mere presence of LDL, which is incorrect more often than not.

The presence of LDL is considered an indicator for the potential risk of heart attacks or coronary disease, but studies have shown that about 75 percent of patients who suffer heart attacks have cholesterol levels that dont indicate a high risk for such an event. Research by Ohio University Distinguished Professor Dr. Tadeusz Malinski and researcher Dr. Jiangzhou Hua in Ohio Universitys Nanomedical Research Laboratory shows that of the three subclasses that comprise LDL, only one causes significant damage.

Our studies can explain why a correlation of total bad cholesterol with a risk of heart attack is poor and dangerously misleading its wrong three quarters of the time, Malinski said. These national guidelines may seriously underestimate the noxious effects of LDL cholesterol, especially in cases where the content of subclass B in total LDL is high (50% or higher).

Malinskis team used nanosensors to measure the concentration of nitric oxide and peroxynitrite in endothelium stimulated by LDL subclasses and reported the findings in a study published in the current issue of International Journal of Nanomedicine. Subclass B of LDL was found to be the most damaging to endothelial function and can contribute to the development of atherosclerosis. Therefore, its not the total amount of LDL cholesterol one has, but rather the concentration of subclass B to the other two, subclass A and subclass I, that should be used to diagnose atherosclerosis and the risk of heart attack.

Understanding this could lead to improving the accuracy of diagnosis for the evaluation of cardiovascular disease rates, Malinski said. Analyzing the mixture of LDL subclasses may provide a parameter-based model for an early medical diagnosis of estimating the risk of cardiovascular disease.

Story Source:

Materials provided by Ohio University. Note: Content may be edited for style and length.

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'Bad cholesterol' is only as unhealthy as its composition: Research demonstrates that current guidelines for diagnosing risk are 'dangerously...

Healthy lifestyle and medication as good as stents and surgery in preventing heart attacks – USA TODAY

Decades of medical wisdom are being called into question after a new study suggests some people with heart disease might be undergoing surgery they don't need. CBC - Health

Common heart procedures such as stents and bypass surgery don't prevent heart attacks or deathsmore often than cholesterol-lowering drugs and lifestyle changesfor millions of Americans with stable heart disease, a new, federally funded study shows.

Cardiologists often use invasive measures such as inserting stents to open clogged arteries or bypass operations to reroute blood around a blocked artery. Findings from the ISCHEMIA study, unveiled Saturday at the American Heart Association's annual meeting,found these procedures donot prevent heart attacks or deaths more effectively thanmedication and lifestyle changes.

However, the study, sponsored by the National Heart, Lung, and Blood Institute,reported people who experience frequent angina, or chest pain, had more reliefafter stents or bypass surgery compared with medicine and lifestyle changes alone.

The largest-of-its-kind study provides compelling evidence forcardiologists to adopt a conservative approach in takingcare of millions of Americans with moderate heart disease, said Daniel Muoz, a Vanderbilt University Medical Center cardiologist.

This study will help us make sure the right patient gets the right treatment, Munoz said. For this subgroup of patients with stable disease and stable symptoms, this study powerfully suggests we ought to have a conversation with the patient and really try to do the most we can with medication.

Study: Young women more vulnerable to heart disease, cardiac woes

For your health: 7 healthy habits that can protect you from heart attack and stroke

Dr. Annapoorna Kini, center, performs a non-emergency angioplasty at Mount Sinai Hospital in New York on Feb. 16, 2017. Through a blood vessel in the groin, she guides a tube to a blockage in the heart. She inflates a tiny balloon to flatten the clog, and leaves behind a mesh tube called a stent to prop the artery open. (Photo: Mark Lennihan, AP)

The question of whether aggressive treatment is more effective than cholesterol-loweringmedications alonehas been controversial in cardiology circles. A study in 2007foundstents or bypass operations were no more effective than medication and lifestyle changes in preventing heart attacks or deaths, but the study was criticized over how it was was designed and conducted.

Any changes in medical practice would affect a sizable population. The American Heart Association estimates17 million people have stable heart disease, 9.4 million with chest pain.

The ISCHEMIA study of 5,179 high-risk patients in 37 countries found no difference in the death rates among people who received stents or bypass operations compared with medication and lifestyle changes.

"The all-cause rates of death were the same," said Judith Hochman, who chaired the study and is a senior associate dean for clinical sciences at the New York University Grossman School of Medicine."We saw no difference in overall survival between the two strategies."

It's common for people to get cardiac stress tests or CT coronary angiograms even though they do not report symptoms. If those tests are abnormal, patients might be sentto a hospital's cath lab to receive a stent or get bypass surgery.

"That strategy is not supported by the data," Hochman said.

'We are at a point of real stagnation': Progress against heart disease stalls

If heart doctors halted such practices, it could save the health care system more than $500 million a year, she said.

The study might prompt discussions among patients and cardiologists based on how to address heart disease. People who exercise frequently or perform rigorous activities might choose to undergo a stent procedure or bypass operation if medication and lifestyle changes don't control frequent chest pain.

Among people who had chest pain once a month, according to the study, 70% of people who received invasive procedures reported they were pain-free compared with40% percent of those who only took statins and adopted lifestyle changes.

"Many patients will come to their doctor or their cardiologist with a bias themselves about what they think needs to happen, including, 'Can we just stent this and fix it?' "Muoz said."Part of our obligation, thanks to a quality study like this, is to make sure they understand what stenting might do and what it might not do for them in the long term."

SOURCE National Institutes of Health; National Heart, Lung and Blood Institute; USA TODAY research(Photo: USA TODAY)

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Healthy lifestyle and medication as good as stents and surgery in preventing heart attacks - USA TODAY

10 Ways To Use Technology For A Healthy And Less-stressful Life – Thrive Global

Technologyhas forever changed the world we live in. Were online, in one way or another,all day long. In our personal and professional lives, technology can be ablessing as it made it easier to connect with others, and a curse that being ina state of always-connected and 24/7 contactable can make it really challengingto take some time to focus on your own well-being or spend time with family andfriends.

The goodnews is that we can turn the tables on the dark side of technology by usingtechnology to our advantage to de-stress and relieve some of the anxiety fromour hectic lifestyle.

I am going to share 10 effective methods that we teach our staff at iDesignYours where technology can help de-stress and develop a healthy lifestyle.

Devices like smartphones, tablets, laptops emit an artificial blue light and staring at screens of our devices all day can cause eye strain, and prevent us from feeling relaxed and sleepy.

UseGoogles Digital Wellbeing for Android Devices that not only chart what you doand for how long, but also packs extra features like turning the screen gray atnight to remind you to put your phone down, or it even outright disables appsafter a set time.

Apple userscan use Screen Time that allows you to monitor how much time you spend usingyour device and what youre doing with it.

Numerous studies have linked noise pollution to increased anxiety, depression, high blood pressure, heart disease, and stroke. A Cardiologist at Johannes Gutenberg University in Mainz, Germany says that noise aggravates these health conditions by inducing higher levels of stress.

Organizingyour time, to-do lists, scheduling events, emails and even going paperless canhelp you reduce the level of stress in your life. Use these simple apps toorganize your life with ease:

You canmake your computer or mobile device remind you to practice good work ergonomicsand break habits with these apps.

Fitness productslike FitBit and Apple Watch can also help you relax.

If you owna FitBit, Apple Watch or Garmin VivoSport, try the guided breathing exercisefeatures to relieve stress when your heart rate variability (HRV) sensor showsyour heart rate and stress level rising.

If youthought that wearables only go on your wrist, you might be surprised to learnabout Vitalis smart bra that will track your HRV and posture, and helpidentify what triggers stress for you.

It is saidthat nowadays there is an app for everything. It is quite true. From moodtracking to squeezing a virtual rubber duck, theres an app or a game foralmost any type of stress relief youre searching for.

Instead ofscrolling through social media and creating more negative energy, utilize apps/gamessuch as Little Wheel, Echogenesis, Pigment or Personal Zen, which contains aseries of games focused on reducing anxiety levels.

Music is considered the best food for your spirit. Listen to your favorite songs to de-stress, or listen to the top 10 relaxing songs ranked by scientists if youre in need of immediate relaxation.

Meditationis one of the oldest techniques in the world to relieve stress and tension.

Schedule 10minutes out of each day, put it in your phones calendar for a reminder, toclear your mind and reset your thought process.

If you feel like you are always on the go, try an app like Simple Habit to develop a practice of meditation in the midst of the busyness of life (during a commute, on a walk, while working).

Acupressure is a homeopathic remedy that uses targeted pressure to clear blockages that could be causing pain, tension, or stress in the body. If youre like me, spending the time and money to actually go visit an acupressure specialist is out of the question. Fortunately, technology has provided us with an app for a guided DIY acupressure process that can be done on your own time.

For betteror worse, our smartphones, tablets, and computers are here to stay so why nottry to harness cutting edge advances in technology to combat the anxiety andstress, and encourage mental and emotional health.

Do you haveany other tips, apps or new technology that can help reduce the stress and letyou lead a healthy lifestyle? Let me know in the comments.

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10 Ways To Use Technology For A Healthy And Less-stressful Life - Thrive Global

Studies Prove Eating This Amount Of Calories Help You Increase Life Expectancy – International Business Times

Doctors are one in saying that your diet has a great impact on your life expectancy. What you eat can significantly determine how healthy you are. There is just one problem, though, there are different kinds of diets available out there. Each of these diets is being advocated by a different set of health specialists.

So the question remains, is there one particular diet that you should follow? Will it then help you live longer.

Factors Involved

According to the health authority site NHS, one secret to living longer is by following a healthy lifestyle. This would include developing a good exercise routine, staying away from cigarettes, reducing alcohol intake, or, if possible, shunning alcohol. A combination of these factors could ensure that you would be able to live a longer and healthier life. low-calorie-diet Photo: pasja1000 - Pixabay

But what is the amount of food that you can eat? Recent studies showed that reducing the number of calories that you eat every day can create a positive impact on your life expectancy.

Reducing Calorie-Intake

A study that was published in the Cell Metabolism Journal revealed that if you reduce the number of calories that you eat by 15% in a span of two years, you will start seeing astounding effects on your body. According to the study, this will help in protecting you from certain diseases like diabetes and cancer. It can even create a positive impact on dementia, which means that your risk of developing this neurological illness will be reduced.

The study, which looked at 53 non-obese individuals, in the age group of 21 to 50, discovered that even if the individuals who participated were already healthy, they still derive benefits from a diet where calorie intake is restricted.

In another study, which was published in Science Translational Medicine, showed that extreme restriction of calories for 5 days in a month for 3 months greatly helped the body fight against aging. Researchers gave participants plant-based vegetable soups and energy bars.

Another study published in Science Translational Medicine also showed an extremely calorie-restricted diet, practiced for five days a month for three months, help the body with aging.

Number of Calories

With these studies telling everyone to cut down calories, the only thing left to be answered is how many calories will you need in a day? As per NHS, men would require 2,500kcal, while women would need 2,000kcal. In some diets, a low-calorie diet would be between 800kcal to 1,500kcal.

Always remember, before you venture into this diet, better seek the advice of your general practitioner. Aside from being healthy, other factors that will affect the number of calories you take in per day would include your age, physical activity, and for women, whether pregnant or breastfeeding.

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Studies Prove Eating This Amount Of Calories Help You Increase Life Expectancy - International Business Times