Text of CIRM Response on the Weakening of Financial Disclosure Requirements


On April 24, the California Stem Cell
Report
asked the state stem cell agency about its proposed changes
in its requirements for financial disclosures from its officials.
Here are the key elements from that query with the stem cell agency's
response following.
The agency was invited to respond to
the following: "The new code appears
to give discretion to the employee to determine what enterprise is
'the type to receive grants or other monies' from CIRM. Additionally,
it would not appear to require disclosure of an investment with or
income from, for example, Kleiner Perkins, which is a major investor
in iPierian, which holds $7 million in CIRM grants and could well be
a future applicant...(T)he weakening of the code comes at a time when
the agency is moving to cozy up to industry and looking to raise
funds to continue its existence, all of which raises even greater
conflict of interest issues than earlier in CIRM's existence."
Here is the text of the response April
25 from Kevin McCormack, CIRM's new senior director for public
communications and patient advocate outreach.

"In answer to your question, we
are proposing changes to the Conflict of Interest Code based upon
recommendations from the California Fair Political Practices
Commission (FPPC). The Political Reform Act requires state
agencies like CIRM to review their Conflict of Interest Codes every
two years.  The FPPC, which is charged with enforcing the
Political Reform Act, is responsible for reviewing and approving
CIRM's Conflict of Interest Code.  In preparation for this
review, CIRM's counsel met with the FPPC staff who suggested the
proposed amendments which are the subject of the upcoming Governance
Subcommittee meeting.  The proposed amendments to CIRM's
Conflict of Interest Code are consistent with the FPPC's position
that agencies should tailor their disclosure categories to type of
work performed by the agency.  For example, CalPERS's
conflict of interest code requires CalPERS officials to disclose
investments in, and income from, entities that are of the type with
which CalPERS contracts and entities in which funds administered by
CalPERS could be invested.  Likewise, the State Board of
Education requires its members to disclose investments, business
positions, and income from a publisher, manufacturer, or vendor of
instructional materials, or services offered to educational
institutions in the State of California and investments, positions of
management and income from any private school in the State of
California.  Similar to these codes, the FPPC proposed that
CIRM's Code be tailored to the nature of CIRM's work.  Thus,
the FPPC proposed that CIRM require its board members and high-level
employees to disclose investments in, and income from, entities that
are of the type with which CIRM would contract or from which CIRM
could procure goods or services as well as investments in, and income
from, biotech and pharmaceutical companies.  Because these
are the types of entities that are likely to create potential
conflicts of interest, we believe the disclosure categories are
appropriate.  It is important to remember, however, that
this is a preliminary proposal.  CIRM will seek input from
the Governance Subcommittee, the Board, and members of the public
before seeking approval of the amendments."

Source:
http://californiastemcellreport.blogspot.com/feeds/posts/default?alt=rss

Sonia Rykiel reveals Parkinson's disease

Tried to pretend nothing was wrong ... Sonia Rykiel.

Sonia Rykiel has revealed she has Parkinson's disease, after finding it impossible to keep secret any longer.

The French fashion designer's health has been called into question over recent months, with claims she has been looking frail.

She made the announcement about her health in a new book called N'oubliez pas que je joue (Don't forget it's a game). The tome is co-written by Judith Perrignon and in it Rykiel talks about the disease.

Advertisement: Story continues below

"Unfashion" ... Malin Akerman wears a Sonia Rykiel dress from the designer's autumn 2011 collection.

"I don't want to show my pain. I resisted, I hesitated, I tried to be invisible, to pretend that nothing was wrong. It's impossible, it's not like me," she says in the book.

The 81-year-old designer discovered she had Parkinson's 15 years ago. She has opened up about it now because she can no longer disguise the signs, such as shaking.

The star has been using a cane for a while now, although those she works with suggested she was never pictured with it.

Rykiel discussed her love of fashion in the latest edition of French Elle. She thinks women get too caught up in trends, when really they need to think about what suits their figures when getting dressed.

View original post here:
Sonia Rykiel reveals Parkinson's disease

Sonia Rykiel reveals Parkinson’s disease

Tried to pretend nothing was wrong ... Sonia Rykiel.

Sonia Rykiel has revealed she has Parkinson's disease, after finding it impossible to keep secret any longer.

The French fashion designer's health has been called into question over recent months, with claims she has been looking frail.

She made the announcement about her health in a new book called N'oubliez pas que je joue (Don't forget it's a game). The tome is co-written by Judith Perrignon and in it Rykiel talks about the disease.

Advertisement: Story continues below

"Unfashion" ... Malin Akerman wears a Sonia Rykiel dress from the designer's autumn 2011 collection.

"I don't want to show my pain. I resisted, I hesitated, I tried to be invisible, to pretend that nothing was wrong. It's impossible, it's not like me," she says in the book.

The 81-year-old designer discovered she had Parkinson's 15 years ago. She has opened up about it now because she can no longer disguise the signs, such as shaking.

The star has been using a cane for a while now, although those she works with suggested she was never pictured with it.

Rykiel discussed her love of fashion in the latest edition of French Elle. She thinks women get too caught up in trends, when really they need to think about what suits their figures when getting dressed.

View original post here:
Sonia Rykiel reveals Parkinson's disease

Tracking Parkinson’s

More than 3,000 volunteers are needed in a groundbreaking clinical study on Parkinsons disease.

IT WAS announced on BBC radio recently that the worlds biggest study into the cause of Parkinsons disease will take place soon. It will be headed by Dr Donald Grosset, a neurologist at Glasgow University in Scotland.

According to the BBC report, Parkinsons disease affects almost 130,000 people in Britain. Parkinsons disease is a debilitating condition. Its symptoms include tremors, mood changes, difficulties in movement, loss of smell and speech problems.

Dr Grosset hopes the milestone research will be able to find better ways of diagnosing and treating the disease. Parkinsons UK is investing more than 1.6mil (RM8mil) in the Tracking Parkinsons study with the long-term aim of boosting the chances of finding a cure.

The 3,000 volunteers include those who have been recently diagnosed with the disease, those who were aged under 50 at diagnosis, and their siblings.

The purpose of the research is to identify markers in the blood which could be used to create a simple diagnostic test for the disease, something which currently does not exist.

Parkinsons medical experts say early diagnosis is crucial for doctors to be able to prescribe the right drugs for people with the condition.

The BBC adds that the responses to various treatments of those taking part in the study will be closely monitored for up to five years.

The project will eventually be linked up to 40 research centres across Britain. Dr Grosset says the cure for Parkinsons disease is a global challenge.

All the samples gathered from our thousands of volunteers will be available for analysis by researchers the world over, he adds.

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Tracking Parkinson’s

Strong support for once-marginalized theory on Parkinson’s disease

ScienceDaily (Apr. 25, 2012) University of California, San Diego scientists have used powerful computational tools and laboratory tests to discover new support for a once-marginalized theory about the underlying cause of Parkinson's disease.

The new results conflict with an older theory that insoluble intracellular fibrils called amyloids cause Parkinson's disease and other neurodegenerative diseases. Instead, the new findings provide a step-by-step explanation of how a "protein-run-amok" aggregates within the membranes of neurons and punctures holes in them to cause the symptoms of Parkinson's disease.

The discovery, published in the March 2012 issue of the FEBS Journal, describes how -synuclein (a-syn), can turn against us, particularly as we age. Modeling results explain how -syn monomers penetrate cell membranes, become coiled and aggregate in a matter of nanoseconds into dangerous ring structures that spell trouble for neurons.

"The main point is that we think we can create drugs to give us an anti-Parkinson's effect by slowing the formation and growth of these ring structures," said Igor Tsigelny, lead author of the study and a research scientist at the San Diego Supercomputer Center and Department of Neurosciences, both at UC San Diego.

Familial Parkinson's disease is caused in many cases by a limited number of protein mutations. One of the most toxic is A53T. Tsigelny's team showed that the mutant form of -syn not only penetrates neuronal membranes faster than normal -syn, but the mutant protein also accelerates ring formation.

"The most dangerous assault on the neurons of Parkinson's patients appears to be the relatively small -syn ring structures themselves," said Tsigelny. "It was once heretical to suggest that these ring structures, rather than long fibrils found in neurons of people having Parkinson's disease, were responsible for the symptoms of the disease; however, the ring theory is becoming more and more accepted for this neurodegenerative disease and others such as Alzheimer's disease. Our results support this shift in thinking."

The modeling results also are consistent with the electron microscopy images of neurons in Parkinson's disease patients; the damaged neurons are riddled with ring structures.

Wasting no time, the modeling discoveries have spawned an intense hunt at UC San Diego for drug candidates that block ring formation in neuron membranes. The sophisticated modeling required involves a complex realm of science at the intersection of chemistry, physics, and statistical probabilities. A kaleidoscope of interacting forces in this realm makes -syn proteins bump and tremble like they're in an earthquake, coil and uncoil, and join together in pairs or larger groups of inventive ballroom dancers.

The modeling is creating a much better understanding of the mysterious a-syn protein itself, according to Tsigelny. A few years ago it was shown to accumulate in the central nervous system of patients with Parkinson's disease and a related disorder called dementia with Lewy bodies.

The new modeling study has revealed precisely how two -syn proteins insert their molecular toes into the membrane of a neuron, wiggle into it in only a few nanoseconds and immediately join together as a pair. The pair isn't itself toxic; however, when more -syn proteins join the dance, a key threshold is eventually crossed; polymerization accelerates into a ring structure that perforates the membrane, damaging the cell.

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Strong support for once-marginalized theory on Parkinson’s disease

Research and Markets: Parkinson's Disease Therapeutics – Parkinson's Disease (PD) Therapeutics Market is Forecast to …

DUBLIN--(BUSINESS WIRE)--

Research and Markets (http://www.researchandmarkets.com/research/c9kszn/parkinsons_diseas) has announced the addition of GlobalData 's new report "Parkinson's Disease Therapeutics - Global Drug Forecasts and Treatment Analysis to 2020" to their offering.

Parkinson's Disease (PD) Therapeutics Market is Forecast to Show Slow Growth to 2020

In 2011, the global Parkinson's Disease (PD) therapeutics market, which includes the key markets of the US, Japan, Germany, the UK, France, Italy, Spain, Brazil, China, India and Russia was estimated to be worth $2,992m. During the period 2002-2011, the global PD therapeutics market grew at a Compound Annual Growth Rate (CAGR) of 5.8%. GlobalData analysis shows that the market size was primarily driven by two key parameters: the increase in PD prevalence due to the increase in the aging population in the 11 key markets and the increasing cost of therapy.

In 2011, the market registered a decline in the market valuations due to the entry of generics for Mirapex (pramipexole) and higher preference for generic ropinirole. The market declined from $3,499m in 2010 to $2,992m in 2011. The US was leading PD therapeutics market, with an estimated value of $1,046m in 2011 and a market share of 35%. Japan was the second biggest market, with an estimated value of $542m and an 18.1% market share, followed by Germany with a market share of 15.6%.

The global PD therapeutics market is primarily served by levodopa, dopamine agonists, Monoamine Oxidase Inhibitors (MAO-BI) and Catechol-O-Methyltransferase (COMT) inhibitors. The market is dominated by branded products such as Boehringer Ingelheim's Mirapex/Mirapexin / Sifrol / Mirapex ER / Mirapexin ER (pramipexole), GlaxoSmithKline's (GSK) Requip/Requip XL (ropinirole), Orion / Novartis' Stalevo/Comtan (carbidopa/levodopa/entacapone) and Teva/Lundbeck's Azilect/Agilect (rasagiline). In addition, a large number of generics are also available in this market.

Key Topics Covered:

1 List of Tables and Figures

2 Parkinson's Disease Therapeutics - Disease Overview

3 Parkinson's Disease Therapeutics - Market Characterization

Read the rest here:
Research and Markets: Parkinson's Disease Therapeutics - Parkinson's Disease (PD) Therapeutics Market is Forecast to ...

Research and Markets: Parkinson’s Disease Therapeutics – Parkinson’s Disease (PD) Therapeutics Market is Forecast to …

DUBLIN--(BUSINESS WIRE)--

Research and Markets (http://www.researchandmarkets.com/research/c9kszn/parkinsons_diseas) has announced the addition of GlobalData 's new report "Parkinson's Disease Therapeutics - Global Drug Forecasts and Treatment Analysis to 2020" to their offering.

Parkinson's Disease (PD) Therapeutics Market is Forecast to Show Slow Growth to 2020

In 2011, the global Parkinson's Disease (PD) therapeutics market, which includes the key markets of the US, Japan, Germany, the UK, France, Italy, Spain, Brazil, China, India and Russia was estimated to be worth $2,992m. During the period 2002-2011, the global PD therapeutics market grew at a Compound Annual Growth Rate (CAGR) of 5.8%. GlobalData analysis shows that the market size was primarily driven by two key parameters: the increase in PD prevalence due to the increase in the aging population in the 11 key markets and the increasing cost of therapy.

In 2011, the market registered a decline in the market valuations due to the entry of generics for Mirapex (pramipexole) and higher preference for generic ropinirole. The market declined from $3,499m in 2010 to $2,992m in 2011. The US was leading PD therapeutics market, with an estimated value of $1,046m in 2011 and a market share of 35%. Japan was the second biggest market, with an estimated value of $542m and an 18.1% market share, followed by Germany with a market share of 15.6%.

The global PD therapeutics market is primarily served by levodopa, dopamine agonists, Monoamine Oxidase Inhibitors (MAO-BI) and Catechol-O-Methyltransferase (COMT) inhibitors. The market is dominated by branded products such as Boehringer Ingelheim's Mirapex/Mirapexin / Sifrol / Mirapex ER / Mirapexin ER (pramipexole), GlaxoSmithKline's (GSK) Requip/Requip XL (ropinirole), Orion / Novartis' Stalevo/Comtan (carbidopa/levodopa/entacapone) and Teva/Lundbeck's Azilect/Agilect (rasagiline). In addition, a large number of generics are also available in this market.

Key Topics Covered:

1 List of Tables and Figures

2 Parkinson's Disease Therapeutics - Disease Overview

3 Parkinson's Disease Therapeutics - Market Characterization

Read the rest here:
Research and Markets: Parkinson's Disease Therapeutics - Parkinson's Disease (PD) Therapeutics Market is Forecast to ...

New Post-Hoc Analyses Examined Neupro® Effects on Pain, Depressed Mood, Apathy and Fatigue in Patients with Parkinson …

ATLANTA--(BUSINESS WIRE)--

Insights into the effects of Neupro (rotigotine transdermal system) on common non-motor symptoms of Parkinsons disease (PD) were presented today at the 64th AAN Annual Meeting in New Orleans, LA.

A post-hoc analysis of data from five, randomized, double-blind, placebo-controlled trials investigated the effect of rotigotine transdermal system on neuropsychiatric features and fatigue in patients with PD. Improvements were observed with rotigotine transdermal system versus placebo in items assessing apathy, anhedonia, anxiety, anxiety/depression, depression and fatigue. In addition, a post hoc analysis of data from the RECOVER* study investigated the effect of rotigotine transdermal system on pain in patients with PD, and in some patients with pain, improvements were observed with rotigotine transdermal system versus placebo.

Post hoc analyses of large amounts of data like these provide valuable insights into the potential impact of rotigotine on the everyday lives of people with Parkinsons, and signal a need for further study in this area, said Professor Robert Hauser, Director, Parkinson's Disease and Movement Disorders Center, University of South Florida, Tampa, FL.

Results presented below should be viewed in the context of the post-hoc analyses. In addition the p-values reported are exploratory and prospective studies are warranted to confirm these findings.

Summary of PD data presented at AAN 2012

ABSTRACT TITLE: Rotigotine transdermal system improves neuropsychiatric features (apathy, anhedonia, anxiety, and depression) and fatigue in patients with Parkinsons disease: A post-hoc analysis of five double-blind placebo-controlled studies

Post-hoc analysis of five placebo-controlled studies of rotigotine transdermal system in patients with early-PD (SP512, SP513), advanced-PD (PREFER, CLEOPATRA-PD), and PD with unsatisfactory control of early-morning motor symptoms (RECOVER) was conducted*. Individual items assessing apathy, anhedonia, anxiety, anxiety/depression, depression and fatigue were identified from the scales used in these studies - the Non-Motor Symptoms Scale (NMSS), the Beck Depression Inventory (BDI-II), the 39-item Parkinsons Disease Questionnaire (PDQ-39), the 8-item Parkinsons disease questionnaire (PDQ-8) and the 5-item EuroQol Group questionnaire (EQ-5D).

ABSTRACT TITLE: Rotigotine transdermal system improves pain in patients with Parkinsons disease: A post-hoc analysis of patients reporting pain in the RECOVER study

RECOVER* (Randomized Evaluation of the 24-hour Coverage: Efficacy of Rotigotine) was a double-blind, placebo-controlled study (n=287) that demonstrated significant improvements in early-morning motor function and nocturnal sleep disturbance with rotigotine transdermal system.* Secondary efficacy measures in the RECOVER study were the Nocturnal, Akinesia, Dystonia and Cramps Score (NADCS) and exploratory outcome measures included the Likert Pain Scale.

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New Post-Hoc Analyses Examined Neupro® Effects on Pain, Depressed Mood, Apathy and Fatigue in Patients with Parkinson ...

Chelsea Therapeutics is a Proud Sponsor of the Parkinson's Unity Walk

CHARLOTTE, N.C., April 25, 2012 (GLOBE NEWSWIRE) -- Chelsea Therapeutics International, Ltd. (CHTP - News) announced today it is proud to serve as a platinum corporate sponsor of the Parkinson's Unity Walk in New York City on April 28, 2012. In addition to sponsoring the walk, Chelsea employees will also participate in the event and raise funds for Parkinson's research.

"As a sponsor of the Parkinson's Unity Walk, Chelsea is helping to fund potentially life-saving research for this devastating disease," commented Dr. Simon Pedder, president and CEO of Chelsea Therapeutics. "Chelsea is committed to helping those with a wide range of autonomic conditions, including Parkinson's disease and Neurogenic OH. We are thrilled to be raising money to support seven of the nation's largest Parkinson's organizations and their premier fundraising event."

The Parkinson's Unity Walk (PUW), a grassroots organization, began in 1994 through the dedicated efforts of patients, families, support groups, and friends who were affected by Parkinson's disease. Their main goal was to raise awareness and funds for research to find a cure for Parkinson's. The Parkinson's Unity Walk directs donated funds to increase research to find a cure. 100% of all donations made to the Parkinson's Unity Walk are distributed among the major U.S. Parkinson's disease foundations for Parkinson's disease research including the American Parkinson Disease Association, the National Parkinson Foundation, the Parkinson's Action Network, the Parkinson's Disease Foundation, The Michael J. Fox Foundation for Parkinson's Research, The Parkinson Alliance and The Parkinson's Institute and Clinical Center. To join a team, make a donation or learn more about the Parkinson's Unity Walk, please visit http://www.unitywalk.org.

About Chelsea Therapeutics

Chelsea Therapeutics (CHTP - News) is a biopharmaceutical development company that acquires and develops innovative products for the treatment of a variety of human diseases, including central nervous system, rheumatoid arthritis, psoriasis and other inflammatory diseases. Founded in 2004 around its library of unique anti-inflammatory and autoimmune technology, Chelsea has further expanded its product development portfolio with early- and late-stage candidates that seek to leverage the company's development expertise and accelerate the company's drug commercialization efforts. For more information about the company, visit http://www.chelseatherapeutics.com.

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Chelsea Therapeutics is a Proud Sponsor of the Parkinson's Unity Walk

Chelsea Therapeutics is a Proud Sponsor of the Parkinson’s Unity Walk

CHARLOTTE, N.C., April 25, 2012 (GLOBE NEWSWIRE) -- Chelsea Therapeutics International, Ltd. (CHTP - News) announced today it is proud to serve as a platinum corporate sponsor of the Parkinson's Unity Walk in New York City on April 28, 2012. In addition to sponsoring the walk, Chelsea employees will also participate in the event and raise funds for Parkinson's research.

"As a sponsor of the Parkinson's Unity Walk, Chelsea is helping to fund potentially life-saving research for this devastating disease," commented Dr. Simon Pedder, president and CEO of Chelsea Therapeutics. "Chelsea is committed to helping those with a wide range of autonomic conditions, including Parkinson's disease and Neurogenic OH. We are thrilled to be raising money to support seven of the nation's largest Parkinson's organizations and their premier fundraising event."

The Parkinson's Unity Walk (PUW), a grassroots organization, began in 1994 through the dedicated efforts of patients, families, support groups, and friends who were affected by Parkinson's disease. Their main goal was to raise awareness and funds for research to find a cure for Parkinson's. The Parkinson's Unity Walk directs donated funds to increase research to find a cure. 100% of all donations made to the Parkinson's Unity Walk are distributed among the major U.S. Parkinson's disease foundations for Parkinson's disease research including the American Parkinson Disease Association, the National Parkinson Foundation, the Parkinson's Action Network, the Parkinson's Disease Foundation, The Michael J. Fox Foundation for Parkinson's Research, The Parkinson Alliance and The Parkinson's Institute and Clinical Center. To join a team, make a donation or learn more about the Parkinson's Unity Walk, please visit http://www.unitywalk.org.

About Chelsea Therapeutics

Chelsea Therapeutics (CHTP - News) is a biopharmaceutical development company that acquires and develops innovative products for the treatment of a variety of human diseases, including central nervous system, rheumatoid arthritis, psoriasis and other inflammatory diseases. Founded in 2004 around its library of unique anti-inflammatory and autoimmune technology, Chelsea has further expanded its product development portfolio with early- and late-stage candidates that seek to leverage the company's development expertise and accelerate the company's drug commercialization efforts. For more information about the company, visit http://www.chelseatherapeutics.com.

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Chelsea Therapeutics is a Proud Sponsor of the Parkinson's Unity Walk

Parkinson's is 'a daily struggle'

Thursday, Apr 26 2012, 4:34 pm

What is Parkinsons disease?

According to the Parkinsons Disease Foundation, Parkinsons is a chronic and progressive movement disorder that involves the malfunction and death of vital nerve cells in the brain, called neurons. Major symptoms are tremor, rigidity, slowness and lack of balance. Some of the other symptoms are depression, emotional changes, pain, memory loss, problems swallowing and chewing, digestive issues, sleep disturbances, fatigue and weight loss.

More information

The monthly Parkinsons Support Group meets at the Neal Senior Center, 100 T.R. Harris Drive, Shelby, at 1:30 p.m. on the second Tuesday of the month. Contact Doug Murphy at 704-487-8822 and dmurphy2@carolina.rr.com.

The quarterly Parkinsons Support Group will meet at 6 p.m. May 22 at the Life Enrichment Center, 110 Life Enrichment Blvd., Shelby. The program will be about the importance of exercise. For more information, call 704-484-0405.

Online

Parkinsons Disease Foundation: http://www.pdf.org/, 1-800-457-6676

Parkinson Association of the Carolinas: http://www.parkinsonassociation.org, 1-866-903-7275

Mention Parkinsons and most people think of tremors, said Doug Murphy, who was diagnosed with the disease in 2009.

Continued here:
Parkinson's is 'a daily struggle'

Parkinson’s is ‘a daily struggle’

Thursday, Apr 26 2012, 4:34 pm

What is Parkinsons disease?

According to the Parkinsons Disease Foundation, Parkinsons is a chronic and progressive movement disorder that involves the malfunction and death of vital nerve cells in the brain, called neurons. Major symptoms are tremor, rigidity, slowness and lack of balance. Some of the other symptoms are depression, emotional changes, pain, memory loss, problems swallowing and chewing, digestive issues, sleep disturbances, fatigue and weight loss.

More information

The monthly Parkinsons Support Group meets at the Neal Senior Center, 100 T.R. Harris Drive, Shelby, at 1:30 p.m. on the second Tuesday of the month. Contact Doug Murphy at 704-487-8822 and dmurphy2@carolina.rr.com.

The quarterly Parkinsons Support Group will meet at 6 p.m. May 22 at the Life Enrichment Center, 110 Life Enrichment Blvd., Shelby. The program will be about the importance of exercise. For more information, call 704-484-0405.

Online

Parkinsons Disease Foundation: http://www.pdf.org/, 1-800-457-6676

Parkinson Association of the Carolinas: http://www.parkinsonassociation.org, 1-866-903-7275

Mention Parkinsons and most people think of tremors, said Doug Murphy, who was diagnosed with the disease in 2009.

Continued here:
Parkinson's is 'a daily struggle'

Huntsville runner with Parkinson's disease to run in marathon

NASHVILLE, Tennessee -- Huntsville resident Jennifer Neathery will be hitting the streets of downtown Nashville Saturday for a 26.2 mile challenge to raise money and awareness about a disease she's battled for seven year's, Parkinson's.

In an effort to promote Parkinson's Awareness Month in the community, Neathery will be participating in the St. Jude Country Music Marathon to raise money for the Parkinson's Disease Foundation. She says her motivation for embarking on the 26.2-mile challenge is to not only generate awareness, but to show that "no matter what your circumstances are, you can do anything you can your mind to."

Neathery, an avid runner, was diagnosed with young onset Parkinson's disease seven years ago at 32. Despite her disease's hardships, Neathery decided to partake in the run to challenger herself and prove to others that Parkinson's doesn't mean "giving up being active and living a good life."

The runner's goal is to raise $500 as she runs in the Nashville marathon on Saturday. She will be one of more than 35,000 participants in the race, which is a part of the Rock 'n' Roll marathon series.

Robin Elliott, the executive director for the Parkinson's Disease Foundation, says champions such as Neathery remind her of what the organization does and why.

"Because Parkinson's affects nearly 1 million Americans and we need to find a cure," he said. "We applaud her efforts to not only help PDF to fund the most promising research, but also to raise awareness in her community and around the U.S. about the impact of the disease."

To learn more about Neathery's fundraising efforts or to donate, contact the Parkinson's Disease Foundation by calling 800-457-6676, visit pdf.org or email info@pdf.org.

See the original post:
Huntsville runner with Parkinson's disease to run in marathon

Huntsville runner with Parkinson’s disease to run in marathon

NASHVILLE, Tennessee -- Huntsville resident Jennifer Neathery will be hitting the streets of downtown Nashville Saturday for a 26.2 mile challenge to raise money and awareness about a disease she's battled for seven year's, Parkinson's.

In an effort to promote Parkinson's Awareness Month in the community, Neathery will be participating in the St. Jude Country Music Marathon to raise money for the Parkinson's Disease Foundation. She says her motivation for embarking on the 26.2-mile challenge is to not only generate awareness, but to show that "no matter what your circumstances are, you can do anything you can your mind to."

Neathery, an avid runner, was diagnosed with young onset Parkinson's disease seven years ago at 32. Despite her disease's hardships, Neathery decided to partake in the run to challenger herself and prove to others that Parkinson's doesn't mean "giving up being active and living a good life."

The runner's goal is to raise $500 as she runs in the Nashville marathon on Saturday. She will be one of more than 35,000 participants in the race, which is a part of the Rock 'n' Roll marathon series.

Robin Elliott, the executive director for the Parkinson's Disease Foundation, says champions such as Neathery remind her of what the organization does and why.

"Because Parkinson's affects nearly 1 million Americans and we need to find a cure," he said. "We applaud her efforts to not only help PDF to fund the most promising research, but also to raise awareness in her community and around the U.S. about the impact of the disease."

To learn more about Neathery's fundraising efforts or to donate, contact the Parkinson's Disease Foundation by calling 800-457-6676, visit pdf.org or email info@pdf.org.

See the original post:
Huntsville runner with Parkinson's disease to run in marathon

Walking with Multiple Sclerosis: Tips to a Good Walk

There are a number of summertime sports and recreational events that I enjoy. I love to go on horseback rides, box, swim, and cycle to name just a few of the sports and recreational events that I enjoy.

I walk every day to help me train for one major event that allows me to make a statement. I walk every day to be ready for the multiple sclerosis walk here in Colorado Springs, Colo. This event allows me to show other people that have multiple sclerosis that they too can beat this disease. That is the reason I walk every day.

Here are some tips and benefits for people thinking about taking up walking for their health that have multiple sclerosis:

Tip number one

Stretching is the most important tip I have for anybody looking to get into walking for their health. I stretch for about 15 minutes before going on any walk, whether that is in my own neighborhood, or anywhere else in the state of Colorado.

I always make sure I stretch before I go on any walk, because of my multiple sclerosis. My multiple sclerosis causes a great deal of pain in my legs if I do not properly stretch before I go on a walk, and this is the reason I always stretch for 15 minutes before I go on a walk.

Tip number two

Warming up is another essential element for my walking. I start off every walk by walking slowly, and then build my way up to a more intense speed. This allows for my muscles to become ready for a good intense walk.

Tip number three

I always ensure that I have a water bottle with me when I go on my walks. This ensures that I'm able to stay hydrated especially since I tend to go for long walks in the summertime.

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Walking with Multiple Sclerosis: Tips to a Good Walk

University of Rochester Researcher Awarded $263,622 for Multiple Sclerosis Research

Grant Funded by American Brain Foundation and National Multiple Sclerosis Society

Newswise NEW ORLEANS - A Rochester, New York, researcher will receive a $263,622 grant to continue his study of injury to brain cell connections (synapses) in multiple sclerosis (MS) through the American Brain Foundation (formerly the American Academy of Neurology Foundation) and the National Multiple Sclerosis Society Clinician-Scientist Development Award.

Matthew Bellizzi, MD, a Fellow in experimental therapeutics and neuroimmunology at the University of Rochester was awarded the fellowship for his work investigating progressive degeneration of the brain in MS patients and in MS models.

The three year award is designed to encourage MS clinical research with the goal of providing better treatment, prevention or cure of the disease.

Clinical research is the fundamental transition stage between discovery and treatment.

Clinical research provides the scientific basis for all forms of care, addresses patient and caregiver needs and is the backbone for drug development and cost-effectiveness studies needed to improve lives. Fellowships provide recipients with up to three years of protected time, with salary that allows them to continue important research projects in their chosen interests.

Multiple sclerosis is an unpredictable disease of the central nervous system that disrupts communication between the brain and other parts of the body. MS patients experience muscle weakness in their extremities and difficulty with coordination and balance, among other symptoms. The progress, severity, and specific symptoms of MS vary from one person to another. There is no known cure for multiple sclerosis at this time, but there are therapies available that may slow the disease and improve quality of life.

The American Brain Foundation, the foundation of the American Academy of Neurology, supports vital research & education to discover causes, improved treatments, and cures for brain and other nervous system diseases. Learn more at http://www.CureBrainDisease.org or find us on Facebook.

The National MS Society addresses the challenges of each person affected by MS by funding cutting-edge research, driving change through advocacy, facilitating professional education, collaborating with MS organizations around the world, and providing programs and services designed to help people with MS and their families move their lives forward. The Society is dedicated to achieving a world free of MS. For more information about the National MS Society, visit http://www.nationalMSsociety.org.

The American Academy of Neurology, an association of more than 25,000 neurologists and neuroscience professionals, is dedicated to promoting the highest quality patient-centered neurologic care. A neurologist is a doctor with specialized training in diagnosing, treating and managing disorders of the brain and nervous system such as Alzheimers disease, stroke, migraine, multiple sclerosis, brain injury, Parkinsons disease and epilepsy.

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University of Rochester Researcher Awarded $263,622 for Multiple Sclerosis Research

Leading Global Multiple Sclerosis Research Center Taps IBM Analytics to Improve Patient Care

ARMONK, N.Y., April 26, 2012 /PRNewswire/ -- IBM (NYSE: IBM) today announced that researchers from The State University of New York (SUNY) at Buffalo are using IBM analytics technology to study more than 2,000 genetic and environmental factors that may contribute to multiple sclerosis (MS) symptoms.

(Logo: http://photos.prnewswire.com/prnh/20090416/IBMLOGO)

As part of the initiative, Researchers will tap into IBM's analytics technology to develop algorithms for big data containing genomic datasets to uncover critical factors that speed up disease progression in MS patients. Insights gained from the research will be shared with hundreds of doctors to better tailor individual treatments to slow brain injury, physical disability and cognitive impairments caused by MS.

Using IBM analytics technology, SUNY Buffalo researchers can for the first time explore clinical and patient data to find hidden trends among MS patients by looking at factors such as gender, geography, ethnicity, diet, exercise, sun exposure, and living and working conditions. The big data including medical records, lab results, MRI scans and patient surveys, arrives in various formats and sizes, requiring researchers to spend days making it manageable before they can analyze it.

Using an IBM Netezza analytics appliance with software from IBM business partner, Revolution Analytics, researchers can now analyze all the disparate data in a matter of minutes instead of days, regardless of what type or size it is. The technology automatically consumes and analyzes the data, and makes the results available for further analysis. As a result, researchers can now focus their time on analyzing trends instead of managing data.

MS is a chronic neurological disease for which there is no cure. The disease is believed to be caused by a combination of genetic, environmental, infectious and autoimmune factors making treatment difficult. According to the National Multiple Sclerosis Society, there are approximately 400,000 people in the US with MS, and 200 people are diagnosed every week. Worldwide, MS is estimated to affect more than 2.1 million people.

"Multiple Sclerosis is a debilitating and complex disease whose cause is unknown. No two people share the exact same symptoms, and individual symptoms can worsen unexpectedly," said Dr. Murali Ramanathan, Lead Researcher at SUNY Buffalo. "Identifying common trends across massive amounts of MS data is a monumental task that is much like trying to shoot a speeding bullet out of the sky with another bullet. IBM analytics helps our researchers fine tune their aim and match the speed of analysis with the rate of data coming into our systems. Our goal is to demystify why the disease progresses more rapidly in some patients and get those insights back to other researchers, so they can find new treatments."

Since 2007, SUNY Buffalo researchers have been at the forefront of studying clinical and historical data from MS patients to identify genetic and environmental factors that contribute to the risk of developing the disease. These researchers are studying different age groups to see why the disease appears early in some children and why people who are diagnosed later in life tend to have a more aggressive course that affects their ability to walk. They are also looking at why MS is more common in northern latitudes and less common towards the equator, calling into question the role sunlight or lack thereof plays in the disease.

"Organizations that glean insights from big data and apply them to pervasive diseases like MS have the potential to greatly change the way patients receive treatment," said Dan Pelino, general manager, healthcare and life sciences at IBM. "The work that SUNY Buffalo is doing is a prime example of how IBM clients are literally changing the world with big data analytics, from advancing medical research, to generating clean energy and giving consumers what they want before they know they want it."

IBM Netezza appliances are optimized systems based on IBM BladeCenter technology that can analyze petabytes of data significantly faster than competing options, and at a much lower total cost of ownership. Unlike competing appliances, Netezza can be up and running in minutes instead of days or weeks.

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Leading Global Multiple Sclerosis Research Center Taps IBM Analytics to Improve Patient Care

Preliminary Data Suggest Spasticity May Be Reduced in Relapsing-Remitting Multiple Sclerosis Patients Who Transitioned …

JERUSALEM--(BUSINESS WIRE)--

Teva Pharmaceutical Industries Ltd. (NASDAQ: TEVA - News) today announced interim data from a prospective, open label survey study evaluating spasticity in patients with relapsing-remitting multiple sclerosis (RRMS) who transitioned to COPAXONE (glatiramer acetate injection) from interferon-beta treatment. These data were presented today at the 64th Annual Meeting of the American Academy of Neurology (AAN) in New Orleans, Louisiana.

Interim results for the first 52 of 110 participants revealed a significant reduction in muscle stiffness, pain and discomfort, as well as the effect of spasticity on the ability to walk, body movements and activities of daily living (ADLs). Improvement was also found in reduction of total spasticity scores during the six month period.

Spasticity, one of the more common symptoms of RRMS, can often negatively impact patients daily lives, said Cira Fraser PhD, RN, ACNS-BC, Associate Professor and Graduate Faculty, Marjorie K. Unterberg School of Nursing and Health Studies, Monmouth University, West Long Branch, New Jersey and Principal Investigator of the study. These data may suggest a reduction in the key measures of spasticity in RRMS patients who discontinued interferon-beta treatment and transitioned to COPAXONE.

The prospective longitudinal survey research study is evaluating 110 participants utilizing the Multiple Sclerosis Spasticity Scale (MSSS-88), the Performance Scales, and a socio demographic questionnaire completed when transitioning between treatments and at month six. Study criteria included participants who had stopped interferon-beta treatment within 30 days; were about to start, or started COPAXONE within the previous 21 days; had spasticity; and were able to ambulate with unilateral support or without. Of the 52 participants, whose data are currently being reported, 35 percent were taking medication for spasticity prior to enrollment and during the six month period.

These study results contribute to the body of knowledge on the treatment of RRMS, said Jon Congleton, Teva's Senior Vice President, Global Brand Strategic Marketing. Through the ongoing support of research such as this, Teva is continually working to help improve the lives of RRMS patients.

ABOUT THE STUDY

Additional detail can be found on the AAN website: http://www.abstracts2view.com/aan/

[P07.074] A Prospective Study of Spasticity in Individuals with Multiple Sclerosis (MS) in Transition from Interferon-Beta to Glatiramer Acetate (Session P07: Multiple Sclerosis: Symptoms, April 26 at 2:00 PM) Cira J. Fraser, West Long Branch, NJ

ABOUT COPAXONE

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Preliminary Data Suggest Spasticity May Be Reduced in Relapsing-Remitting Multiple Sclerosis Patients Who Transitioned ...

Tennis: Game Point on Multiple Sclerosis

I first started to play tennis back in the summer of 2009, when I first heard the name and story of Sue Burke. Sue Burke is not just any tennis player though. Sue was diagnosed with multiple sclerosis just like I was in 2006. The story of Sue Burke is what actually made me start to play sport of tennis.

Sue is a world class tennis coach who coached the American women's team at one of the highest venues in the world. Sue was an American women's Pan American Games coach in Argentina. The fact that she is still active in the sport though is the reason I decided to give tennis a try, and I fell in love with the sport.

This is the reason I will bring you my top ten benefits for playing tennis with multiple sclerosis.

Benefit number one

Tennis is not a sport that requires constant energy like football, basketball, and hockey. This means that I do get short periods of rest in between the speed and agility that playing tennis does require. This allows me to play a complete game on my good days.

Benefit number two

Do to my multiple sclerosis I had a period of time where I was fighting to regain my reflexes, and my reaction times. These are things that my doctor regularly checks up on when I go to my appointments. I have been able to regain both my reflexes and reaction time through the sport of tennis.

Benefit number three

Tennis much like swimming has been responsible for giving me back my balance. The stop and go motions of playing tennis is the reason I can move better today than I could six years ago, when I was first being diagnosed with multiple sclerosis.

Benefit number four

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Tennis: Game Point on Multiple Sclerosis

Dementia study by Royal Aust College

The Royal Australian and New Zealand College of Psychiatrists' Faculty of Psychiatry of Old Age welcomes the Australian government's announcement of initiatives for people with dementia and services to support aged care, but says more is need for the mental health needs of people in old age.

'Investment in dementia care and diagnosis and improved aged care services are essential and will go some way to improving the lives of older people with mental illness, and those of their families and carers. Improved access to services that support the person in their own home is particularly welcome,' said Dr Roderick McKay, Chair of The Royal Australian and New Zealand College of Psychiatrists' Faculty of Psychiatry of Old Age.

'In the next 20 years the number of Australians over 65 will double, therefore the mental health care of older people is an important part of in the mental health reform agenda. Planning for the mental health needs of older people and access to mental health care is critical to mitigate against poor mental health outcomes,' said Dr McKay

'Focus on this important area is welcomed, and needs to be built upon so that there is comprehensive support for the mental health of older people. As Minister for Mental Health and Ageing, as well as Social Inclusion, Minister Butler would appear to have an almost unique opportunity to achieve this,' said Dr McKay.

'Older people need to be included in all mental health planning to improve their quality of care, remove discrimination and obtain better understanding of the mental health needs of older Australians. It is vital these issues be considered in the government's Ten Year Roadmap for Mental Health Reform,' said Dr McKay.

'Untreated mental illness robs older Australians of their quality of life, physical health and independence at significant cost to individuals, family and community. While there are effective mental health treatments for older people, limited resources can deny them equitable access. Australia owes its older citizens and their families adequate support, respect, and dignity,' said Dr McKay.

'To improve the quality of mental health care for older people we require national benchmarks for the availability and quality of mental health services for older people, and need national principles for providing coordinated care across different services for older Australians with mental illness. Basic mental health training for people working with older Australian is also essential,' said Dr McKay.

For further information Kirrily Johns +61 3 9601 4940

About The Royal Australian and New Zealand College of Psychiatrists The Royal Australian and New Zealand College of Psychiatrists (RANZCP) is the principal organisation representing the medical specialty of psychiatry in Australia and New Zealand and has responsibility for training, examining and awarding the qualification of Fellowship of the College to medical practitioners.

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Dementia study by Royal Aust College