Solano County leaders to discuss eliminating longevity pay

A rather contentious issue at times and now up for discussion today by the Solano County Board of Supervisors is the elimination of longevity pay of Solano County employees -- but only for new hires.

At the request of Supervisor Barbara Kondylis, supervisors will consider elimination of longevity pay over a period of time for people who are not currently employed by the county.

"It didn't go very far when I brought it up before," Kondylis said. "It's based on people taking up space, not on performance."

After thinking about it for a long time, she said the board can be convinced to eliminate the longevity pay if it doesn't touch current employees.

In fiscal year 2009-10, the county paid more than $3.1 million in longevity pay. That number jumped to $3.2 million the next fiscal year.

"These costs are not sustainable given the current county structural deficit," staff said in a report.

Kondylis added that since longevity pay is tied into salaries, eliminating the benefit will also reduce retirement costs.

It would be difficult and probably illegal, according to staff, to eliminate longevity pay for those who are currently working for the county due to contracts and other employment agreements.

"Our goal should be to eliminate longevity for new hires in a way that is fair so that, over time, these costs will no longer occur," staff said in a report.

Staff also noted that none of the actions regarding longevity pay are intended to effect

those who are currently employed by Solano County, including elected officials.

The board will consider several options:

* Eliminate the legislative, executive and senior management groups longevity tier and substitute longevity tier that is in place for all other groups of new hires.

* Eliminate the "credit service provision" for all future hires.

* Eliminate longevity pay for all newly elected officials who take office after Jan. 1, 2013.

* Adopt policy that it is the intention of the Solano County Board of Supervisors to eliminate longevity pay in its entirety for new hires.

The Solano County Board of Supervisors meets at 9 a.m. today in the County Administration Center, 675 Texas St., Fairfield.

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Melissa Murphy at Twitter.com/ReporterMMurphy.

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Solano County leaders to discuss eliminating longevity pay

NASA/NSTA Ultraviolet Radiation and Yeast: Radiation Biology Web Seminar

As part of a series of electronic professional development experiences for educators, the NASA Explorer Schools project and the National Science Teachers Association are hosting a 90-minute live professional development Web seminar for educators on Feb. 8, 2012, at 6:30 p.m. EST. The student activity featured in this seminar demonstrates the effects of radiation on living organisms. Participants will learn how sun-screening materials protect live yeast cells from harmful ultraviolet, or UV, radiation and countermeasures for UV radiation and discuss phenotypic changes in yeast as a result of radiation damage. Participants will learn how different sun protection materials may be used to expand the range of items tested in this lab. See how you can bring a real-world connection between science and education to your students.

For more information and to register online, visit http://learningcenter.nsta.org/products/symposia_seminars/NES2/webseminar11.aspx .

To learn more about the NASA Explorer Schools project, visit http://explorerschools.nasa.gov.

Email any questions about this opportunity to NASA-Explorer-Schools@mail.nasa.gov.

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NASA/NSTA Ultraviolet Radiation and Yeast: Radiation Biology Web Seminar

Science fair Feb. 17 at ABAC

February 7, 2012 Science fair Feb. 17 at ABAC

TIFTON — The School of Science and Mathematics at Abraham Baldwin Agricultural College will host the Regional Science and Engineering Fair on Feb. 17 in Thrash Gym.

Students in grades 6-12 who have participated in a local science fair in their county or school and have been chosen to participate at the regional level will be involved. Projects will be entered in one of 16 different classifications such as behavioral and social sciences, physics and astronomy, animal sciences, plant sciences, and chemistry.

Displays will be available for viewing by the public from 3 – 4 p.m. The awards ceremony will be held at 3:30 p.m. in Howard Auditorium.  Awards will be given to the top two finishers in both the junior and senior divisions.

For more information, interested persons can contact Dr. Ray Barber, Dean of the ABAC School of Science and Mathematics, at (229) 391-5100.

Copyright 2012 Tifton Gazette. All rights reserved. This material may not be published, broadcast, rewritten or redistributed.

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American CryoStem Completes Cell Processing for Clinical Study

RED BANK, NJ--(Marketwire -02/07/12)- American CryoStem Corporation (OTCQB: CRYO.OB - News) announced today that it has completed providing stem cell processing services for Personal Cell Sciences Corp., a cutting edge manufacturer of anti-aging skin care products.

The study involves researching the regenerative function of a conditioned medium obtained from each participant's adipose (fat tissue) derived mesenchymal stem cells and their ability to promote the production or secretion of collagen, elastin and fibronectin related to skin wound healing.

John Arnone, CEO of American CryoStem and Founder of Personal Cell Sciences, commented, "CRYO's patented tissue culture media and its proprietary, aseptic adipose tissue processing methodology allows, as an added benefit for PCS customers to store a clinical grade sample of their own stem cells for future use in regenerative medicine. We are pleased to provide comprehensive Bio-Insurance storage solutions at our clinical facility."

The adipose tissue samples were acquired utilizing a mini-liposuction procedure. A total of sixty milliliters (approximately 2 fluid ounces) of adipose tissue was collected in the physician's office and sent to CRYO's laboratory for processing. Once processed, the resulting stromal vascular fraction (SVF) was forwarded to the Personal Cell Sciences laboratory for proprietary formulation for patient specific products.

"We are very excited to announce our service agreement and participation in this clinical study for Personal Cell Sciences. This contractual manufacturing agreement reinforces our capabilities to provide CRYO's exceptional clinical processing for relevant adult stem cell related products," said Anthony Dudzinski, COO of American CryoStem. "We look forward to our continued business relationship with PCS and expanding these services to other developers to speed their product's time to market."

About American CryoStem: American CryoStem Corporation (OTCQB: CRYO.OB - News) markets clinical processing products and services for Adipose (fat) Tissue and Adipose Derived Adult Stem Cells. CRYO's clinical processing and preservation platform supports the science and applications being discovered globally by providing the highest quality, clinically processed cells and assuring their sterility, viability and growth cap abilities, while at the same time developing cutting edge application, therapies and laboratory products and services for consumers and physicians.

The Private Securities Litigation Reform Act of 1995 provides a "safe harbor" for forward-looking statements. Certain of the statements contained herein, which are not historical facts, are forward-looking statements with respect to events, the occurrence of which involve risks and uncertainties. These forward-looking statements may be impacted, either positively or negatively, by various factors. Information concerning potential factors that could affect the Company is detailed from time to time in the Company's reports filed with the Securities and Exchange Commission.

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American CryoStem Completes Cell Processing for Clinical Study

New Anti-Aging Treatments Make it Easier to Turn Back the Clock

Newswise — SCHAUMBURG, Ill. (Feb. 7, 2012) – As we age, our skin undergoes a number of changes affecting its texture, volume and appearance. Fortunately, dermatologists can use fillers or lasers to correct the most notable signs of aging and can recommend skin care products with added ingredients that can further repair damaged skin.

“Many fillers for the aging face are now designed to create a fuller, more youthful appearance, instead of targeting only wrinkles or fine lines. In addition, facial rejuvenation with lasers is now more targeted, resulting in quicker results and less downtime,” said dermatologist Jenny Kim, MD, PhD, FAAD, associate professor of medicine, division of dermatology, University of California, Los Angeles. “Couple these treatments with the wide range of inexpensive skin care products with high-quality ingredients that are now available and patients can see dramatic results for many problem areas.”

New Fillers Pump up the Volume
While skin fillers and botulinum toxin are the most widely used procedures to rejuvenate the skin, Dr. Kim explained that the newest fillers being introduced will work as volumizers to replace the plumpness of the face that is lost with aging. Similar to how a balloon deflates over time, the face loses its roundness or fullness – the sign of a youthful appearance – with age.

“As much as lines and wrinkles make us look older, we’re learning that volume loss is just as critical,” said Dr. Kim. “Because of that, we’re looking at the aging process a little differently now and understanding the importance of replacing volume loss in the face to restore the fullness of a more youthful appearance.”

Most facial volume loss occurs after age 40, although some people start noticing this change in their late 30s. When this happens, areas of the face that were once full get depressed and are made more prominent by shadowing or darkening – making the face look older.

The newest filler introduced and approved by the U.S. Food and Drug Administration (FDA) for facial rejuvenation is calcium hydroxylapatite. This filler restores facial volume and promotes collagen production, lasting for up to a year in most cases. This calcium hydroxylapatite filler is thicker than the hyaluronic acid fillers currently available, requiring less product to be used. However, Dr. Kim noted that the thickness of calcium hydroxylapatite also is associated with slightly higher adverse effects than hyaluronic acid fillers.

“I expect that we’ll see more advances in volumizing fillers in the near future, which should offer patients better results and fewer side effects,” said Dr. Kim. “Since each filler has unique advantages and disadvantages, it is important that patients discuss their expectations with their dermatologist to determine which procedure is best for them.”

Lasers Focus in on Skin Repair
New laser technologies offer another alternative to rejuvenate the skin with fewer side effects than earlier lasers. For example, fractional photothermolysis is a newer technology that works by targeting a very small percentage of the skin during each treatment, improving the damaged area and resulting in less adverse effects and downtime for the patient. Even pulsed-dye lasers, which have been around for a long time, have evolved so a dermatologist can treat visible broken blood vessels without bruising the skin by adjusting the laser to the patient’s skin.

“Laser technology continues to evolve and provide dermatologists with more options to target not only specific signs of aging, but specific cells responsible for age-related changes in our appearance,” said Dr. Kim. “In the future, lasers could even produce significant skin tightening or effectively target oil glands to improve acne, decrease oily skin and reduce large pores.”

Skin Care Products Offer Daily Dose of Vitamins and Antioxidants
Patients looking to supplement their treatments or those not yet ready for anti-aging treatments in a dermatologist’s office, but who would still like to see some improvement in their skin, can look for over-the-counter skin care products. Once sold exclusively at high-end department stores, a vast assortment of anti-aging products is now available at drug stores.

Dr. Kim recommends that patients look for ingredients such as retinoids (chemical compounds derived from vitamin A), peptides (smaller proteins that stimulate collagen production), and growth factors (compounds that act as chemical messengers between cells and play a role in collagen production). Added into inexpensive skin care products, these have the ability to repair skin damage from sun exposure or other toxic chemicals and, in some cases, stimulate collagen production.

Future Technologies to Watch
Another area of research for its potential anti-aging properties is stem cell technology. Since fat cells contain adult stem cells, their use for facial rejuvenation is being explored. The idea is that if stem cells from fat can be signaled to turn into skin structure, they could potentially make a person look younger by adding volume to depressed facial areas. Dr. Kim explained that while this is an exciting area of research, the efficacy and safety of this technology has not been tested in large clinical studies.

“Outstanding research by skin scientists and dermatologists is leading to better active ingredients in skin care products and advancements in filler and laser technology. As a result of these advances, there is now a range of products and treatments that can improve a person’s skin, no matter the budget.”

Headquartered in Schaumburg, Ill., the American Academy of Dermatology (Academy), founded in 1938, is the largest, most influential, and most representative of all dermatologic associations. With a membership of more than 17,000 physicians worldwide, the Academy is committed to: advancing the diagnosis and medical, surgical and cosmetic treatment of the skin, hair and nails; advocating high standards in clinical practice, education, and research in dermatology; and supporting and enhancing patient care for a lifetime of healthier skin, hair and nails. For more information, contact the Academy at 1-888-462-DERM (3376) or http://www.aad.org. Follow the Academy on Facebook (American Academy of Dermatology) or Twitter (@AADskin).


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Suzanne Somers Uses Stem Cell Therapy for Breast Reconstruction

Suzanne Somers, a breast cancer survivor who’s become known for her controversial advice against chemotherapy, has done something that other women can truly find hope in. She turned to stem-cell techniques to successfully reconstruct her breasts.

The actress, 65, underwent a lumpectomy and radiation 12 years ago, and since then, she says, she wasn’t happy with the appearance of her breasts.  The radiation, she told “People” magazine, "left what breast I had flatter and flatter. I had a Double D on one side and on the other side I could hardly fill a B."

Dissatisfied with conventional breast-reconstruction procedures,  the “Three’s Company” veteran researched further and discovered that  Dr. Kotaro Yoshimura, a Japanese surgeon, had  developed stem-cell breast reconstruction in 2004. After talking with Yoshimura, Somers was convinced and decided to go with an American doctor for the operation.

So she began a clinical trial that has been ongoing at Hollywood Presbyterian Medical Center.  The first patient to participate, Somers had fat removed from her stomach via liposuction. Then her surgeon, Dr. Joel Aronowitz, harvested stem cells from half the fat and combined it with the remaining amount.

After that, Aronowitz injected the mixture back into Somers’ breast until it matched her left one in size.  (Somers had reduced her DD left breast to a C.)

Somers said she’s thrilled with the result and the implications for other breast-cancer survivors. I am so ensconced in what's cutting edge," she told “People.” "I get my thrill out of passing on information to women so they can have a better quality of life."

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Women's Health, Nutrition, Fitness, Motivation, tip of the day, at ILovePrettyKeli.com – Video

22-10-2011 15:00 Visit http://www.Iloveprettykeli.com this is a women's health website that has daily tips on nutrition, fitness, motivation and more! I came up with the idea for this site after receiving numerous replies to my "how to lose 20lbs in 2 weeks" video. It inspired me to work hard providing women with information that can help them daily. Nutrition The nutrition section gives women daily tips on foods they should add to their diet, foods they shouldn't eat, as well as healthy receipes, and diets. iloveprettykeli.com Exercise: This section was made to give you some ideas on different exercises you can try in order to acheive your particular fitness goals. iloveprettykeli.com Motivation: This was designed to provide daily motivation to women who need that extra boost. We all need to be motivated from time to time. This section will not only motivate you, but it will provide you with ideas on how you can motivate yourself iloveprettykeli.com Tip of the day: Check here daily for tips on your overall physical health, as well as mental health. iloveprettykeli.com Special Posts: Every Monday is "motivation monday" This is the day to put yourself or a woman you know in the spotlight by sharing her motivational story with me. If you have someone you would like to feature send me a message letting me know their story along with a name and a picture. They might be chosen! ^_^ Iloveprettykeli also has daily tips for women as well as nutritional information, how to videos a quote of the day tips ...

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Muscle Nutrition's Tawna Eubanks 1 week out from Pro Debut! – Video

11-10-2011 15:35 In Tawna's final week before her IFBB Pro Bikini Debut at the Houston Pro, on October 15th 2011,she polishes her posing and presentation. Coached by Jeff Dwelle and Greg McCoy, the Bikini Rockstars team is prepped with every attention to detail, ensuring that these competitors bring the top packages to the NPC and IFBB stages with their conditioning, poise, and confidence. Join Tawna as she puts on the finishing touches, reflects on her journey, and even shows off her stage suit for her fans!

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How Fast Food is Designed For Addiction

21-12-2011 13:12 Friend @ http://www.facebook.com How Fast Food is Designed For Addiction and Obesity, Psychetruth Nutrition, Corrina Related Video; Why is Junk Food Junk and Superfoods Super? Psychetruth Nutrition http://www.youtube.com Mind Control in a Can, Soft Drinks Aren't Sexy, Coke, Pop http://www.youtube.com Top Ten Obesity Causing Foods -- Psychetruth Nutrition and Weight Loss http://www.youtube.com Fast Foods and Processed Foods Vs Whole Foods, Nutrition and Wellness http://www.youtube.com Top 10 Worst Foods for Health, Weight Loss and Wellness http://www.youtube.com Visit The Official Psychetruth website at; http://www.psychetruth.net This video was produced by Psychetruth http http://www.psychetruth.blogspot.com http http://www.facebook.com http://www.twitter.com http://www.myspace.com Music By Jimmy Gelhaar http://www.jimmyg.us © Copyright 2011 Target Public Media, LLC. All Rights Reserved. fast food addiction how designed obesity psychetruth nutrition "fast food" "junk food" addictive "weight loss" "weight gain" corrina "worst foods" "soft drinks" MSG Caffeine how

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Facebook FanPage Exclusive- Nutrition – Video

28-01-2012 19:59 NUTRITION...NUTRITION...NUTRITION guys and gals. That's what's probably missing out of your equitation to your success. Check out http://www.acfitbody.com for more about fitness, nutrition, supplements and more! TEAM Optimum Nutrition IFBB PRO Physique Athlete Follow me on Twitter! twitter.com http://www.alexcarneiro.com

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Multitalented Detroiter loves being Telly Monster in ‘ Sesame Street Live’

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Telly (rear) is played by Angelo Williams.

Angelo Williams as Telly Monster, appearing in "Sesame Street Live: Elmo’s Super Heroes" at the Fisher Theatre.

Former Detroiter Angelo Williams is touring with the company of "Elmo's Super Heroes" as Telly Monster.

Former Detroiter Angelo Williams has a degree in biochemistry; maybe as many stamps in his passport as Hillary Clinton; and a fuzzy purple alter ego.

Williams, 28, who graduated from Detroit’s High School of Arts, plays Telly Monster, one of the eponymous superheroes of “Sesame Street Live – Elmo’s Super Heroes.”

An “Army brat” born in Nuremberg, Germany, Williams was already well travelled before hitting Motown, Main Street and, finally, touring with Sesame Street. After graduating from high school, Williams did a year at Wayne State University before heading south to dance at Disney World in shows such as the Magic Kingdom’s Main Street Trolley Show and The Festival of the Lion King at Disney’s Animal Kingdom.

He credits a lot of water and Gatorade with his survival. “It’s a lot of hard work, especially in the summer when it’s 98 degrees when you’re in a button-up shirt and vest,” Williams said.

While in Orlando, Fla., he had a visit from a friend and fellow dancer from the Freedom Dance Expressions Company, who was touring with "Dragon Tales Live." Like "Sesame Street Live," it was produced by the VEE Corp. He spent time with the "Dragon Tales" company while they were performing in Orlando, and was invited to audition.

He began his first tour with "Sesame Street Live" in 2005, as Big Bird in “Super Grover Ready for Action,” the original version of the recently updated “Elmo’s Super Heroes.”

Williams has toured with each of the three touring casts of "Sesame Street Live" for the last seven years, playing both Big Bird and Telly, who was Williams’ favorite as a kid.

“He’s very quirky and he’s very spastic, too. He can be very upbeat and then be down a little,” said Williams.

The three casts tour the East Coast, the West Coast and the theater circuit with different shows, and each has international stops. Williams said his most interesting stop was Singapore. The company spent New Year’s Eve in Mexico City, where the soundtrack for the show is in Spanish.

He says that Sesame Street is every bit as beloved around the world as it is here at home. Continued...

“The show offers so much for all ages,” said Williams, whose favorite song in the current show is a take on “One” from “A Chorus Line.” “It’s like we’re in a Broadway show.”

Between tours, Williams earned a dual degree in dance education and biochemistry from the University of Central Florida. His residence is in Newark, Del.

He likes to read, and do gymnastics and has participated on competition cheer teams. The last book he read was the final Harry Potter book, which he saved for after seeing the movie, because he didn’t want to be disappointed. This way, Williams’ reasons, “The book just totally fills in the blanks.”

Asked if he’s interested in the movie business, Williams laughed. "Not unless I hit the lottery.”

Williams has a 6-year-old nephew and a niece on the way. His nephew has seen “every show I’ve been in since he was born. I’m the cool uncle.”

The next move for the multitalented Williams “is to figure out a longterm goal.” He says he is “getting ready for family mode” now, and would like to either open a dance studio and teach or put his biochemistry degree to work in research, where he’s leaning toward pharmaceuticals.

But his most immediate plan is to hustle off to Buffalo for another opening and another show of "Sesame Street Live."

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New Governance Structure Approved by AMP Membership

Newswise — BETHESDA, MD, February 6, 2012 – The members of the Association for Molecular Pathology voted in favor of adopting significant changes to the structure of its governing body. The changes resulted in two primary refinements; 1) a shift from management by a Council to management by a Board of Directors and an Executive Committee, and 2) the transition of Subdivision Chairs from the role of Annual Meeting programming to one that focuses directly on the interests and needs of the subdivision discipline.

The shift from the Council model to a Board and Executive Committee structure allows the Board to continually appraise the Association at a high level and to develop long-range goals, plans, and policies, thus allowing the Executive Committee to focus on operational issues including the implementation of the strategy, direction, and policies established by the Board. The overall strategy of management by a Board and Executive Committee, adopted by an increasing number of nonprofit organizations, allows for greater flexibility, adaptability, and nimbleness on the part of AMP to establish and easily modify its direction moving forward.

AMP’s membership includes four distinct subdivisions; Genetics, Hematopathology, Infectious Diseases, and Solid Tumors. Each subdivision represents a vital segment of AMP membership, reflecting the diversity, vitality, and wide range of specialties encompassed by AMP members.

“AMP has now matured as an organization and is ready to be governed differently than when it was founded,” said Iris Schrijver, MD, AMP President. “Over the course of several months, we studied many aspects of nonprofit governance, examined other organizations, and discussed how to create a model that best suits AMP. Our new governance structure will facilitate decision-making that is informed and strategic.”

The overarching catalyst for the changes to the AMP governance structure is the newly implemented strategic plan. The plan centers on five essential areas: advocacy, education, innovation and improved patient care, governance, and management. AMP’s policies, programs, resources and structure will all serve to support these elements of the strategic plan. For more information about the AMP Strategic Plan, visit http://www.amp.org.

ABOUT AMP:
The Association for Molecular Pathology (AMP) is an international medical professional association dedicated to the advancement, practice, and science of clinical molecular laboratory medicine and translational research based on the applications of molecular biology, genetics, and genomics. For more information, please visit http://www.amp.org/about/strategic_plan.cfm.

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New Governance Structure Approved by AMP Membership

Ask Keri Glassman: Diet, Nutrition & Health Questions!

Nutritionist Keri Glassman is joining Access' Healthy Hollywood team! Keri, who regularly shares her expert wellness advice on Access Hollywood Live , will now be answering your nutrition, diet & health questions.

Want to know which foods to use to slim down fast? Or, how to curb cravings? Ask Keri anything!

PLAY IT NOW: Access Hollywood Live: Richard Simmons Whips Billy Bush & Kit Hoover Into Shape!

Post your question on the Access Hollywood Live Facebook page, and we will choose one great question a week to be answered Thursdays in our Healthy Hollywood column. Plus, Keri might even answer your question live on the air during her Access Hollywood Live segments (airing every other Thursday, beginning Feb. 16)

CLICK HERE to submit your questions!

VIEW THE PHOTOS: On The Set: The Stars Visit Access Hollywood Live (Feb. 2012)

Plus, be sure to "Like" Keri Glassman's page on Facebook, HERE !

Copyright 2012 by NBC Universal, Inc. All rights reserved. This material may not be published, broadcast, rewritten or redistributed.

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CHOOSING A MICROSCOPE FOR SOIL MICROBIOLOGY by Dr. Elaine Ingham – Video

22-05-2011 12:19 Dr. Elaine Ingham gives advice on choosing a microscope for soil microbiology. Dr. Ingham is a world-renowned soil microbiologist who pioneered many of the currently used biological soil amendment techniques and pioneered the testing of soil microbial life as an indicator of soil and plant health. Dr. Ingham is the Chief Scientist at the Rodale Institute. She is the founder of the Sustainable Studies Institute and the Soil Foodweb Inc. soil testing labs. Dr. Ingham is the key author of the US Dept. of Agriculture's Soil Biology Primer. She has been the mentor of numerous soil scientists and practitioners of ecologically balanced landscape design, and has helped farmers all over the world to grow more resilient crops by understanding and improving their soil life.

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New Study Suggests an Unconventional Approach May Help Boomers Prolong Retirement Savings

SAN DIEGO, CA--(Marketwire -02/06/12)- Brandes Investment Partners today released a new study by the Brandes Institute suggesting ways for investors to improve their financial prospects in retirement, including reducing the risk of outliving their assets ("money death"). The baby boom generation is now moving towards retirement age while longevity estimates suggest that their retirement may last much longer than expected. The study suggests that many of America's baby boomers could increase their retirement assets at advanced ages by maintaining a larger portion of their portfolios in higher-potential investments such as equities (rather than re-allocating prematurely into fixed income) and managing the risk of money death by investing a modest portion of their portfolio in longevity insurance. The study comes on the heels of the U.S. Treasury's plan to make it easier for defined contribution plans and IRAs to offer annuity options.

"Retirees in good health have a risk of outliving their assets regardless of their investment strategy. Our study suggests they may do better by aiming for superior long-term returns in their investment portfolios and dealing with money death risk separately," said Barry Gillman, Research Director, Brandes Institute Advisory Board. "This contradicts the conventional wisdom, which tells people to play it safe when they retire by moving a large portion of their portfolio to bonds.

"One problem with the conventional approach is that about 60% of the money distributed from typical retirement accounts should come from investment returns earned after retirement. Today's historically low yields are just not providing the returns retirees will likely need to sustain them.

"Until now, this approach has not been widely understood or used even by the healthy and wealthy individual investors who stand to benefit from it most. With the Treasury's new initiative to tear down some of the barriers to investing retirement savings in annuities, this could also become a practical solution for many participants with 401(k) and IRA savings."

The study cites evidence generated by the Brandes Retirement Simulator, a proprietary online model that projects a range of long-term asset outcomes based on an individual's personal finances and expected lifespan, as well as portfolio allocations and investment assumptions, and the use of longevity insurance. The full study is available on the firm's website at http://www.brandes.com/institute. Access to the Brandes Retirement Simulator will soon be available on the firm's website at no cost to retirees and advisors who can customize the inputs and integrate it into their retirement planning.

About Brandes

Brandes Investment Partners is a global investment advisory firm based in San Diego and along with its affiliates, manages more than $32 billion of assets as of December 31, 2011, for institutional and private clients worldwide. Since its inception in 1974, Brandes has applied the value investing approach to security selection pioneered by Benjamin Graham. Among the first investment firms to bring a global perspective to value investing, Brandes manages a variety of investment strategies.

Brandes Investment Partners, L.P. is a U.S. registered investment adviser. Brandes does not sell or endorse any insurance policy. More information can be found at http://www.brandes.com.

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New Study Suggests an Unconventional Approach May Help Boomers Prolong Retirement Savings

James A. Shapiro: Purposeful, Targeted Genetic Engineering in Immune System Evolution

Your life depends on purposeful, targeted changes to cellular DNA. Although conventional thinking says directed DNA changes are impossible, the truth is that you could not survive without them. Your immune system needs to engineer certain DNA sequences in just the right way to function properly.

Today's blog is a tale of how cells engineer their DNA molecules for a specific purpose. It also illustrates how an evolutionary process works within the human body.

Your immune system has to anticipate and inactivate unknown invaders. Living organisms deal with unpredictable events by evolving. They change to adapt to new circumstances. Variation comes from their capacity for self-modification. Cells have many molecular mechanisms that read, write, and reorganize the information in their genomes, the DNA molecules used for data storage.

The adaptive immune system executes basic evolutionary principles in real time. It has to recognize and combat unknown (and utterly unpredictable) invaders. Immune system cells have to produce antibody molecules that can bind to any possible molecular structure.

How do cells with finite DNA, and finite coding capacity, produce a virtually infinite variety of antibodies? The answer is that certain immune cells (B cells) become rapid evolution factories. They generate antibodies with effectively limitless diversity while preserving molecular structures needed to interact with other parts of the immune system.

Immune cells achieve both diversity and regularity in antibody structures. They accomplish this by a targeted yet flexible process of natural genetic engineering: they cut and splice DNA.

Diversity is strictly limited to a special part of the antibody molecules: a "variable" region encoded by engineered DNA. DNA encoding the "constant" region does not change in the same way. The diversity-generating process is called "VDJ recombination" because it involves cutting and splicing together different "variable" (V), "diversity" (D) and "joining" (J) coding segments. Immune cells do this by cutting DNA at defined "recombination signal sequences." There are hundreds of V segments, about a few dozen D segments, and ten J segments. The various combinations of different spliced segments makes for a tremendous amount of diversity.

Antibodies contain two paired protein chains: a longer heavy chain and a shorter light chain. The heavy chain variable coding region forms by splicing V, D, and J segments together. The light chain variable coding region forms by joining V and J segments together. There are at least 10,000 VDJ combinations and 1,000 VJ combinations. Altogether, over 10,000,000 different heavy + light chain antibodies are possible through "combinatorial diversity."

Not bad... but not good enough.

VDJ recombination generates additional diversity. Although cutting the V, D, and J segments is precise, immune cells join each pair of cleaved DNA segments at about a dozen different positions. Connection between the same two segments can have about 30 to 35 possible different sequence outcomes. This "junctional diversity" adds over 1,000 possible antibody combinations.

In addition, heavy chain D segment joining has another virtually unlimited source of variability. Immune cells have an enzyme that attaches unique new DNA sequences to either end of the D segment. These are not encoded anywhere in the genome. Such so-called "N region" sequences can add over 1,000 new variations to each existing VDJ combination.

So the total possible genetically engineered antibody diversity is something above 10,000,000 X 1,000 X 1,000 = 10,000,000,000,000 combinations. This extraordinary number appears to be large enough to generate antibodies that can protect you from virtually any invader, whatever its molecular structure may be.

The immune system is itself a rapid evolutionary process, replacing one set of immune specificities with another. The right antibody-producing cells multiply when an invader enters the body. Antibodies sit on the surface of cells that made them. When a particular variable region binds an invader, that event sends a signal inside the cell to begin dividing.

Dividing immune cells are called "activated B cells," which proliferate into distinct populations. Because the descendants of a single activated B cell share the same engineered variable region coding sequences, they produce even more invader-recognizing antibodies. By binding, these antibodies signal the rest of the immune system to begin eliminating the invaders. This is the front-line "primary" adaptive immune response.

In a future blog, I'll explain ongoing natural genetic engineering as activated immune cells mature in the "secondary" response. It is no less amazing. For now, let's draw three conclusions from the initial rapid evolution system. We see that:

Evolution has produced a system that engineers DNA with a specific purpose: encoding proteins that bind to unpredictable invaders and signal the immune system to make more antibodies and eliminate the invaders. Precise targeting of DNA cutting to variable region-coding segments allows the basic antibody structure to stay the same. At the same time, its recognition/binding capacity changes. Your B cells are able to combine several different kinds of DNA biochemistry into a functional engineering process: 1) cutting the V, D and J segments; 2) joining the cleaved segments; and 3) synthesizing and inserting the N region sequences.

In the immune system, "purposeful" and "having a predestined outcome" are far from the same thing. Your immune system follows a regular process, but the end result is not fixed in advance. This is an important lesson to keep in mind as we witness ongoing public debates over evolutionary DNA change.

In biology, the alternative to randomness is not necessarily strict determinism. If the cells of the immune system can use well-defined natural genetic engineering processes to make change when change is needed, there is a scientific basis for saying that germ-line cells might do the same in the course of evolution.

 

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James A. Shapiro: Purposeful, Targeted Genetic Engineering in Immune System Evolution

Group: DNA of man convicted of rape does not match attacker

The DNA of a man convicted of raping a College of William & Mary student in 1978 does not match that of her attacker, a University of Virginia School of Law program announced Monday.

The Innocence Project is working to have the conviction of Bennett Barbour, 56, of Williamsburg, overturned, according to a news release.

Barbour was found guilty of the rape based on the victim’s eyewitness identification, even though her previous description of her attacker was different, the release said.

He was sentenced to 18 years, but paroled after serving five years because other evidence came to light casting doubt on his conviction, according to the Innocence Project. His blood type was different than the alleged perpetrator’s, according to the release.

Barbour’s DNA sample is among roughly 1,000 from crimes dating back to the 1970s that then-Virginia Gov. Mark R. Warner ordered tested.

The Innocence Project said the DNA sample in Barbour’s case matched that of a convicted sex offender, who is currently out on parole. The state has not revealed the man’s identity.

The Virginia Attorney General's Office has ordered a second DNA test to verify that Barbour’s DNA does not match the attacker’s. If the second test verifies the original result, the Innocence Project Clinic said it will file a petition for a writ of actual innocence with the Supreme Court of Virginia requesting that Barbour's conviction be overturned.

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Group: DNA of man convicted of rape does not match attacker

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New DNA Product Simplifies Science and Gives Consumers Affordable Access to People and Places Their DNA Most Closely …

ConnectMyDNA™ announced today that it has nationally launched its revolutionary new DNA testing product for the consumer market, offering secure and affordable genetic testing to people all over the world. ConnectMyDNA™ is the first DNA testing product which provides results in an engaging visual and social environment. DNA Diagnostics Center (DDC), a world leader in DNA testing, is the parent company of ConnectMyDNA™.

FAIRFIELD, Ohio (PRWEB) February 06, 2012

ConnectMyDNA™ announced today that it has nationally launched its revolutionary new DNA testing product for the consumer market, offering secure and affordable genetic testing to people all over the world. ConnectMyDNA™ is the first DNA testing product which provides results in an engaging visual and social environment. DNA Diagnostics Center (DDC), a world leader in DNA testing, is the parent company of ConnectMyDNA™.

ConnectMyDNA™ features the Gene Ring™, which is a revolutionary new concept in DNA technology that merges modern art with cutting edge science. Not only is it an eye-catching symbolization of a person’s unique genetic makeup, it's also a scientifically accurate tool that allows a person to visually compare their DNA profile to friends, families and population groups around the world. Using 13 specific markers in a person’s DNA, the same used by forensic sciences for identification purposes, ConnectMyDNA™ matches these markers to DNA of population groups in over 60 countries to determine the ten country populations that a person most closely matches. No two Gene Rings™ are alike, but some are more connected than others and discovering those connections is what ConnectMyDNA™ is all about.

“ConnectMyDNA™ initially launched through HomeRun.com as a test to determine the sustainability of the product and demographics of its users. Within days of launching, ConnectMyDNA™ sold over 1000 units, making it one of the top selling products for HomeRun.com. This is a product which is simple to use, affordable and engaging for everyone. Customers receive an easy-to-use DNA Collection Kit containing the information, instructions, and tools they need to collect a sample of their DNA with a simple cheek swab. The next step is to send the package back to ConnectMyDNA™ in a prepaid envelope and await results. When a customer receives their results, they can securely view their Gene Ring™, a visual illustration of their genetic makeup, online,” said Peter Vitulli, DDC President and CEO.

Vitulli added, “The Gene Ring™ doesn’t contain any genetic information regarding the person’s health or genetic predisposition and is generated using a proprietary technology stored in a secure database so that genetic information can’t be decoded. ConnectMyDNA™ is not intended to be an ancestry test or product – instead it is designed to be a fun, educational product that introduces people to the world of DNA through the Gene Ring™ and population matches. Although the test is based on science, the results can be entertaining as well as enlightening and are an exciting way for people around the world to compare their genetic similarities to their family, friends, and others.”

There are many social features available through ConnectMyDNA™. Customers receive their results online and are offered a variety of ways to view their genetic data, learn about the people and places that their DNA most closely matches, and share their Gene Ring™ with their friends on their favorite social networks.

About DNA Diagnostics Center (DDC), Parent Company of ConnectMyDNA™

DDC is one of the largest DNA testing companies in the world. Founded 17 years ago, DDC offers comprehensive DNA testing services for paternity and other family relationships, forensics, cell line authentication, and ancestry. DDC receives more than 800,000 consumer calls each year, and has performed over 1 million DNA tests since the company was established. The Company is known for its groundbreaking technologies, including an exclusive license for the most innovative and accurate non-invasive prenatal paternity test using SNP (single-nucleotide polymorphism) Microarray Technology, which only requires a simple blood draw from the mother and alleged father. DDC’s unique Dual Process™ ensures all professionally collected DNA samples are independently tested twice producing legal results of unmatched quality and reliability. DDC is recognized through a number of accreditations nationally and internationally achieving perfect ratings in its past 16 inspections including those performed by the American Association of Blood Banks (AABB) and the College of American Pathologists (CAP). DDC is also accredited by ACLASS to meet the standards of ISO 17025 and the American Society of Crime Laboratory Directors Laboratory Accreditation Board International and follows the DNA Advisory Board (DAB) guidelines, which attests to DDC’s superior forensic testing service. For more information: http://www.dnacenter.com or 1-800-362-2368.

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Jan Strode
CEO Advisors
619-890-4040
Email Information

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New DNA Product Simplifies Science and Gives Consumers Affordable Access to People and Places Their DNA Most Closely ...

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