The Genetic Engineering Generation – Huffington Post

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Over a year ago, I read an article about the genetic engineering of human embryos and I immediately knew that the world was in trouble. Todays article in The Times has only confirmed my fears.

Its not that Im afraid of scientific progress or the eventual certainty that our species will customize offspring like video game characters. I accept that people will one day be born who are immune to cancer, asthma, and blindness. When that day comes, when the benefits of genetic engineering have been studied, tested, and perfected, the results will be extraordinary: a world where - physically speaking at least - no one will ever be born unlucky.

Creating a world free from the misfortunes of birth defects and genetic diseases will truly be one of our species' greatest accomplishments. The trouble, though, is how we get there.

Those of us alive today are going to live through a complicated transition. Some day in the next decade or two, some of us will be regular people, and some of us will have been born with the benefits of genetic engineering.

How are you going to react to the other side?

How will you feel about a "designer baby" who grows up and competes for your job or takes your child's place at an elite college? Should these people have less rights than you and me? Or should they should have special protections, considering the resentment they are sure to engender?

These are the questions I set out to explore in my novel, The Ones, and it is urgent that we as society begin to address these issues now.

Consider what scientists are already capable of: the relatively recent discovery of CRISPR-Cas9 has created a gene editing tool that can cut, add, or replace parts of our DNA sequence. Think of this as similar to the "find and replace" function in your word processing program.

Altering DNA used to be painstaking and imprecise. Now, with CRISPR and a computer, Darwin could bang out a new finch family from the Beagle business center.

Even more remarkable, whatever changes are made in the original DNA of a human embryo would endure unaltered in the germline. In layman's terms, this means that future generations would continue to have this altered gene - forever. The potential effects on the genetic makeup of humanity are extraordinary and totally unpredictable.

A real-world experiment along these lines is beginning to play out already, albeit not with humans. Using CRISPR technology, biologists have been able to engineer female mosquitos that pass defective breeding genes to all of their offspring, in effect creating a generation of sterile mosquitos that cannot propagate their species. The benefits of releasing these genetically engineered females into an area beset by Zika or malaria are easy to see.

It is striking to note that laws concerning this technology are different in every country. Some nations have banned research in the field outright. Here in America, there are strict guidelines, but no legally enforceable restrictions. Besides the odd headline, why is no one talking about this? When was the last time you heard a politician utter the words genetic engineering?

For now, much of the world appears to be operating under the policy of let's-agree-not-to-do-anything-too-crazy. Call me a cynic, but pretty much all of history proves this policy is a recipe for disaster. Stopping advances in technology is impossible; waiting too long to deal with them responsibly is all too common.

As with most new technology, only the very wealthiest citizens will have access to genetic engineering at first. Will this benefit be tolerated by the rest of the natural-born masses? Should it? Could this divide lead to outright war?

Today, in America and around the world, ambitious scientists are pushing the envelope on gene editing. Their motives may be driven by altruism, profit or curiosity. One country might want better Olympic athletes. Perhaps another country identifies the genes for scientific aptitude and tries to breed a genius who can solve global warming. No matter what prompts the advancements, the results are inevitable: a new category of humans will be born.

We should embrace this new generation with both a wary eye and open arms. But let's get our act together now so we can nail that awkward hug.

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The Genetic Engineering Generation - Huffington Post

How behavioral science can help tackle problem of idling engines – Science Daily


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How behavioral science can help tackle problem of idling engines
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Research in behavioural science has demonstrated how even very minimal cues or 'nudges' can sometimes have a powerful influence on human behaviour and decision-making. In this study, the researchers applied this approach to examine whether simple ...

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How behavioral science can help tackle problem of idling engines - Science Daily

Thumbs Up for Science – Stanford Social Innovation Review (subscription)

All too often, people use intuition, along with trial and error, to devise social programs. Sometimes they guess right and the programs are effective. But many times they guess wrong and the programs fail to meet their goals.

Some fields, such as education, are fairly advanced in their knowledge about human behavior and have devised ways to incorporate that knowledge into their work (think schools and teacher education).

But most fields are not as sophisticated. They either havent taken the time to understand how knowledge of human behavior might impact their work. Or they are sloppy and inconsistent in applying that knowledge in the programs that they run. Consider some anti-drug campaigns. If it were really as easy as getting people to Just Say No, the United States wouldnt have the opioid epidemic that it now has.

In recent years, however, the behavioral sciencespsychology, cognitive science, neurology, behavioral economics, and other disciplineshave advanced significantly. We now have a large and growing body of knowledge about how people interact with their environment and with each other in a wide variety of settings. And its time we begin applying that knowledge more consistently in the social sector.

This issue of Stanford Social Innovation Review has several feature articles that do just that. The first is our cover story, The New Science of Designing for Humans, by Piyush Tantia, the co-executive director of ideas42, arguably the leading consultancy on how to use behavioral economics to solve social problems. Tantia argues that organizations should adopt a scientific approach to designing social programs. Byputting behavioral science and impact evaluation together we can design more like engineers than like artists, writes Tantia. He goes on to propose an approachdubbed behavioral designto help create programs in a variety of settings.

The second feature article on behavioral science is Stop Raising Awareness Already, written by two University of Florida scholars. The authors argue that all too often organizations focus their eff orts on raising awareness about an issue, with little thought about how to get people to then act on that awareness. If the goal were to raise awareness among new parents of the importance of immunizing children, you wouldnt be satisfied if parents were simply aware, write the authors. Youd want to be sure that they were also having their children immunized for the right diseases at the right age.

The third article that addresses this subject is Embedding Education in Everyday Life, by three Harvard University scholars. They propose embedding education in everyday experiences, such as having barbers who cater to African-American men provide customers with information on hypertension. Embedded education, they argue, is a more reliable way to reach certain groups of people, and its more effective because the education takes place between people who have a pre-existing relationship and capitalizes on what we know about lifelong learning and behavior change.

But it takes time to learn about behavioral science and then more time to incorporate that knowledge into a program. Its hard work, and not as fun as brainstorming with Post-it Notes. But it is time well spent because the difference between a program that is well-designed and one that isnt can be significant.

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Thumbs Up for Science - Stanford Social Innovation Review (subscription)

ACTC Science Fair celebrated youth projects – Journal-Times

Carter County students did well in the 5th annual ACTC/FIVCO Science and Engineering Fair on Feb. 3 at Ashland Community and Technical College.

This fair is awesome, said Ethan Tiller, an eighth grade student from East Carter Middle School. He and classmate Treven Tussey entered a behavioral science project called Are You Judging Me. Their project won a first place award.

Our project was interesting, Tiller said. We wanted to see how people are judged based on the way they dress, such as country, goth and preppy. We were surprised to find that country rated lowest.

The fair showcased 124 science projects from 45 schools and home schools representing all FIVCO counties.

We participate every year, said Lisa Baldwin, fourth grade teacher at Prichard Elementary. Science, technology and math knowledge is the wave of the future, and our students need to know how to use them.

Projects were entered in five categories: Biomedical & Behavioral Health; Animal, Plant & Environmental; Math, Engineering & Computers; Chemistry; and Physics & Astronomy.

First, second and third place awards were given in each category. Each middle school and high school award included a medallion and a cash prize of $100 for first place, $80 for second place and $60 for third place. Teachers of students who won first place received a $50 gift card from the National Science Teachers Association.

This years event was a result of the continuous support of our volunteers, teachers and students who are committed to student success, said Fair Director Mia Brown. A special thanks goes to our sponsors Toyota Motor Manufacturing, Kentucky, Inc., Kings Daughter Medical Center, Marathon Petroleum Company and Big Sandy Superstore.

All award winners in the middle and high school categories are eligible to enter the Regional Science and Engineering Fair held at Northern Kentucky University.

Award winners are listed below by category.

Elementary Awards

Biomedical & Behavioral Health Sciences: 2nd - Brett Dailey and Tyler Stinson from Olive Hill Elementary School, 3rd - Savannah Adams and Addison Tiller from Prichard Elementary School.

Animal, Plant & Environmental Sciences: 2nd Place - Brody Shearer from Star Elementary in Carter County.

Math, Engineering, & Computer Sciences: 2nd - Jacob Holbrook from Prichard Elementary.

Chemistry: 1st- Ariah Egleston and Autumn Egleston from Olive Hill Elementary.

Middle School Awards

Biomedical & Behavioral Health Sciences: 1st -Ethan Tiller and Treven Tussey from East Carter Middle School; 3rd - Lucas Rayburn from West Carter Middle School.

Physics & Astronomy: 1st - Josiah Combs and Samuel Sherrard from East Carter Middle School.

Chemistry: 2nd - Adam Burnett and Aston Tiller from Easter Carter Middle School, 3rd - Arianna Biliter and Raychel Anguiano from West Carter Middle School.

High School Awards

Animal, Plant, & Environmental Sciences: 3rd - Trey McGlone from West Carter High School

Math, Engineering, & Computer Sciences: 1st - Catheryn Holbrook from West Carter High School.

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ACTC Science Fair celebrated youth projects - Journal-Times

The Hunger Gains: Extreme Calorie-Restriction Diet Shows Anti-Aging Results – Scientific American

The idea that organisms can live longer, healthier lives by sharply reducing their calorie intake is not exactly new. Laboratory research has repeatedly demonstrated the anti-aging value of calorie restriction, often called CR, in animals from nematodes to ratswith the implication that the same might be true for humans.

In practice though, permanently reducing calorie intake by 25 to 50 percent or more sounds to many like a way to extend life by making it not worth living. Researchers have also warned that what works for nematodes or rats may not workand could even prove dangerousin humans, by causing muscle or bone density loss, for example.

But now two new studies appear to move calorie restriction from the realm of wishful thinking to the brink of practical, and perhaps even tolerable, reality. Writing in Nature Communications, researchers at the University of WisconsinMadison and the National Institute on Aging reported last month chronic calorie restriction produces significant health benefits in rhesus monkeysa primate with humanlike aging patternsindicating that CR mechanisms are likely translatable to human health. The researchers describe one monkey they started on a 30 percent calorie restriction diet when he was 16 years old, late middle age for this type of animal. He is now 43, a longevity record for the species, according to the study, and the equivalent of a human living to 130.

In the second study, published this week in Science Translational Medicine, a research team led by gerontologist Valter Longo at the University of Southern California (U.S.C.) suggests it is possible to gain anti-aging benefits without signing up for a lifetime of hunger. Instead, a fasting-mimicking diet, practiced just five days a month for three monthsand repeated at intervals as neededis safe, feasible and effective in reducing risk factors for aging and age-related diseases.

Some researchers, however, still find the calorie-restriction argument unpersuasive. Leslie Robert, a biochemist and physician at the University of Paris who was not involved in the two new studies, says pharmaceutical approaches offer greater anti-aging potential than inefficient and apparently harmful diets. The important thing, adds Luigi Fontana, a longevity researcher at the Washington University School of Medicine in Saint Louis who also was not involved in the new work, is if youre doing a healthy diet, exercising, everything good, without doing anything extreme, without making life miserable by counting every single calorie.

Rozalyn Anderson, a researcher in the Wisconsin study, does not necessarily disagree. Life is difficult enough without engaging in some bonkers diet, she says. We really study this as a paradigm to understand aging. Were not recommending people do it. The combined results in the Nature Communications paper show aging is malleable in primates, she explains, and that aging itself presents a reasonable target for intervention. Whereas conventional medicine views aging as a fight against cancer, cardiovascular issues, neural degeneration and other diseases, she adds, calorie restriction delays the aging and vulnerability. Instead of going after diseases one at a time, you go after the underlying vulnerability and tackle them all at once.

Despite her reservations about recommending CR, Anderson praised the work of the research team in the Science Translational Medicine study for pushing this forward for possible application in clinics. In that study, test subjects followed a carefully designed 50 percent calorie restricted diet (totaling about 1,100 calories on the first day and 70 percent (about 700 calories) on the next four days, then ate whatever they wanted for the rest of the month.

Longo, the gerontologist at U.S.C., says the underlying theory of the on-again/off-again approach is that the regenerative effects of the regimen occur not so much from the fasting itself as from the recovery afterward. By contrast, long-term, uninterrupted calorie restriction can lead to the sort of negative effects seen in extreme conditions like anorexia.

The calorie-restricted diet in Longos study was 100 percent plant-based and featured vegetable soups, energy bars, energy drinks and a chip snack as well as mineral and vitamin supplements. It included nutrients designed to manipulate the expression of genes involved in aging-related processes, Longo explains. (Longo and U.S.C. are both owners of L-Nutra, the company that manufactures the diet. But he says he takes no salary or consulting fees from the company and has assigned his shares to a nonprofit organization established to support further research.)

Even the five-day-a-month calorie restriction regimen was apparently a struggle for some test subjects, resulting in a 25 percent dropout rate. But health benefits in the form of decreased body mass and better levels of glucose, triglycerides and cholesterol, along with other factors, showed up after the third month and persisted for at least three monthseven after subjects had returned full-time to a normal diet. Notably, given concerns about other forms of calorie restriction, lean muscle mass remained unchanged.

The benefits were greater for people who were obese or otherwise unhealthy, Longo says. But those individuals might also need to repeat the five-day regimen as often as once a month to the point of recovery, he adds, whereas individuals who are already healthy and athletic might repeat it just twice a year.

Neither of the two new studies argues the benefits of CR necessarily add up to a longer life. Longevity in humans is still an unpredictable by-product of our myriad variations in individual biology, behavior and circumstance. The objective, according to researchers, is merely to make the healthy portion of our lives last longer.

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The Hunger Gains: Extreme Calorie-Restriction Diet Shows Anti-Aging Results - Scientific American

Metro MediSpa's Testosterone Therapy Benefits Men's Hearts – Satellite PR News (press release)

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WILMINGTON, NC, February 15, 2017 Testosterone therapy has now been shown to be beneficial for older men knocking down the long-held assertion that it was detrimental to their hearts. Men can now regain their youthful vitality and ease the symptoms that accompany low testosterone levels.

What is Testosterone Therapy?

Hypogonadism is a disease in which the body is unable to produce normal amounts of testosterone due to a problem with the testicles or with the pituitary gland that controls the testicles. The symptoms of low testosterone include: loss of bone density and muscle mass, increased body fat, osteoporosis, diminished sexual drive, erectile dysfunction, anemia, frailty, depression, and coronary disease. Testosterone therapy is a way for men to improve the signs and symptoms of this disease. By opting for testosterone therapy, men can increase the amount of testosterone in their body up to sufficient levels.

Is it harmful to heart patients?

In the past, it was assumed that testosterone therapy posed potential health risks to men, like heart attacks and strokes. However, this is not true according to the latest research. The researchers at Intermountain Medical Center Heart Institute have presented a new study which deduces that testosterone therapy can help heart patients a great deal. The study shows that heart patients given testosterone therapy showed much better results than the patients not receiving the treatment.

The study further claims that the notion that testosterone therapy increases the risk of heart attacks and strokes is not correct. It discovered that heart patients who did not receive any testosterone therapy were 80% more likely to suffer a heart attack or stroke than the ones who received the therapy.

How was the study conducted?

The study involved 755 male patients suffering from heart disease ranging in age from 58 to 78, and tested the patients in groups of three. Each group was given testosterone therapy in the form of a gel or by injections, and their heart conditions were monitored for possible effects.

The results of this study are a significant leap in medical history. It concludes that contrary to the popular belief that testosterone therapy harms a mans heart, the use of this therapy can be improved or prevent heart disease. This study will help define further medical strategies related to heart conditions and problems. Now older men with low testosterone levels can be treated without fear of causing heart problems and allow them to continue active lifestyles.

Overall, our study suggests that what is best for mens health is to keep testosterone levels balanced and within a normal range, said Dr. Connie Odom.

ABOUT METRO MEDISPA Owned and operated by Connie Odom, M.D., Board Certified Anesthesiologist and American Academy of Anti-Aging Medicine Certified Physician. Metro MediSpa has changed the way cosmetic procedures are performed by introducing the first medically directed mobile spa in the Southeast.

Through anti-aging medicine along with advanced cosmetic treatments, our experienced team of medical professionals is committed to bring the beauty of an improved appearance and an inner age defying wellness to all.

Motivated by the belief that health and wellness affects all areas of ones life and having the knowledge in safe and effective cosmetic treatments, the staff at Metro Medispa can help people correct imperfections that had become uncomfortably noticeable.

Submit the press release

A new study shows that testosterone therapy reduces heart attacks in older men with heart disease.

WILMINGTON, NC, February 15, 2017 Testosterone therapy has now been shown to be beneficial for older men knocking down the long-held assertion that it was detrimental to their hearts. Men can now regain their youthful vitality and ease the symptoms that accompany low testosterone levels.

What is Testosterone Therapy?

Hypogonadism is a disease in which the body is unable to produce normal amounts of testosterone due to a problem with the testicles or with the pituitary gland that controls the testicles. The symptoms of low testosterone include: loss of bone density and muscle mass, increased body fat, osteoporosis, diminished sexual drive, erectile dysfunction, anemia, frailty, depression, and coronary disease. Testosterone therapy is a way for men to improve the signs and symptoms of this disease. By opting for testosterone therapy, men can increase the amount of testosterone in their body up to sufficient levels.

Is it harmful to heart patients?

In the past, it was assumed that testosterone therapy posed potential health risks to men, like heart attacks and strokes. However, this is not true according to the latest research. The researchers at Intermountain Medical Center Heart Institute have presented a new study which deduces that testosterone therapy can help heart patients a great deal. The study shows that heart patients given testosterone therapy showed much better results than the patients not receiving the treatment.

The study further claims that the notion that testosterone therapy increases the risk of heart attacks and strokes is not correct. It discovered that heart patients who did not receive any testosterone therapy were 80% more likely to suffer a heart attack or stroke than the ones who received the therapy.

How was the study conducted?

The study involved 755 male patients suffering from heart disease ranging in age from 58 to 78, and tested the patients in groups of three. Each group was given testosterone therapy in the form of a gel or by injections, and their heart conditions were monitored for possible effects.

The results of this study are a significant leap in medical history. It concludes that contrary to the popular belief that testosterone therapy harms a mans heart, the use of this therapy can be improved or prevent heart disease. This study will help define further medical strategies related to heart conditions and problems. Now older men with low testosterone levels can be treated without fear of causing heart problems and allow them to continue active lifestyles.

Overall, our study suggests that what is best for mens health is to keep testosterone levels balanced and within a normal range, said Dr. Connie Odom.

ABOUT METRO MEDISPA Owned and operated by Connie Odom, M.D., Board Certified Anesthesiologist and American Academy of Anti-Aging Medicine Certified Physician. Metro MediSpa has changed the way cosmetic procedures are performed by introducing the first medically directed mobile spa in the Southeast.

Through anti-aging medicine along with advanced cosmetic treatments, our experienced team of medical professionals is committed to bring the beauty of an improved appearance and an inner age defying wellness to all.

Motivated by the belief that health and wellness affects all areas of ones life and having the knowledge in safe and effective cosmetic treatments, the staff at Metro Medispa can help people correct imperfections that had become uncomfortably noticeable.

Press release service and press release distribution provided by http://www.24-7pressrelease.com

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Metro MediSpa's Testosterone Therapy Benefits Men's Hearts - Satellite PR News (press release)

Grey’s Anatomy Round Table: Should Owen and Amelia Just End It? – TV Fanatic

OnGrey's Anatomy Season 13 Episode 12the tension between Eliza and Bailey and the rest of the attendingscould be cut with a knife. Upon Catherine's return to GSM, Bailey made her boldest move yet and suspendedMeredith.

The rumors and gossip were flying as the others tried to figure out why Andrew dropped the charges against Alex. And Maggie's mother stopped by for a visit, only to receive devastating news.

Below, TV Fanatics Tiffany and Jasmine as they discuss Catherine's return to GSM, the Jo/Alex/Andrew love triangle... and much more!

Andrew dropped the charges against Alex. Are you pleased with how they resolved this, or do you feel like it was weak?

Tiffany: I'm not very happy with it. The show built up the case for so long then we barely saw anything leading to DeLuca's change of heart. Yeah, we know he has feelings for Jo and we now know Warren put the ball in motion for him to drop the charges, but to have him rush in like that felt cheap.

Jasmine: I have mixed feelings on the issue. In fact, based on how they resolved it, I'm annoyed that they ever bothered to make this a story line to begin with. They did spend a lot of time building it up, only to have it written off so easily.

It's like they wrote themselves into a corner and then didn't know how to write themselves out of it.

It's been brewing for some time now, but it appears as if they really are heading into an Alex/Jo/Andrew love triangle. How do you feel about it?

Tiffany: I feel like there's a natural way the show can do it if they don't force a love triangle.

I can see Alex pushing Jo towards DeLuca because she deserves better and DeLuca's the better guy and I can even see Jo trying to make things work with DeLuca because girls always try to make it work with the good guy. But ultimately, Jo loves Alex and that's who she'll end up with.

Jasmine: I think it's forced, and I want no parts of it. I'd rather see more of Andrew developing as a character on his own before they toss him into the fray with Jo. I can see what Tiffany's saying, happening on the show, but that's not even fair to DeLuca.

He already got raw deal being dragged into Jolex drama. I'd rather see him back with Maggie.

Watch Grey's Anatomy Season 13 Episode 12 Online

Everyone at GSM fell in love with Diane Pierce. Did you? How did you feel about her finding out she has breast cancer and not telling Maggie after Maggie's outburst?

Tiffany: I liked her but I had completely forgotten she left Maggie's father and in Maggie's opinion, blew up their family life. I get what she was saying about being happy for the first time & not apologizing for it, but you still have to be respectful of your children and their feelings.

Of course, it's incredibly sad that she has breast cancer. I hope she tells Maggie before it's too late for them to make up and say good bye. I can't imagine it'll be easy for Jackson to keep that secret and, though he's bound by doctor/patient confidentiality, my guess is he'll tell Maggie eventually.

Jasmine: I really liked her. She was such a fun person. It's had to believe that she and Maggie are related because Maggie is so awkward and neurotic and her mother is so easygoing. I agree with Tiffany.

I know a lot of people tend to be hard on Maggie, but she's trying to adjust to the news of her parents' divorce, and she had to get that out.

I'm so upset that she found out she had breast cancer. Can any family member appear without being sick or bringing loads of drama? Sheesh! I don't think Jackson will tell Maggie about her mother. He can't. Which means he'll be in a really awkward position.

I get why Diane didn't tell Maggie after her outburst, but I'm sad that she didn't.

13 TV Marriages We Wish Were Ours

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Not only did Bailey suspend Meredith, but she replaced her with April. React.

Tiffany: Bailey, Bailey, Bailey... all I can say is, WTF? I understand she's pissed the attendings aren't "falling in line" but why shouldn't they have a say in what goes on in their OR's, with their patients?

It's their careers on the line after all. Initially, I think Bailey was trying to do what she thought was in the best interests of everyone, but now I just think her pride is hurt and she's on a power trip.

Even Dr. Minnick told her to stop interfering this week. As for April, she's officially Bailey's puppet, and I hope she's ready for the hate the attendings are going to unleash on her.

Jasmine: Meredith's reaction was priceless. She's so cool, calm, and collected. She just went home like it was no big deal. I loved her exchange with Alex. And then when she found out Kepnerreplaced her; she said her name like it was diseased. Haha! I love Bailey, but she is not coming across likable with this situation.

13 Characters We'd Never Ask to Be Our Valentines

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The razor-wire case inspired Owen to try to reason with Amelia. Do you think she'll finally talk to him after that?

Tiffany: I don't know what to think about that relationship. I'm not even sure why she left anymore. Was it shame over the child she lost? Guilt over not being pregnant after trying ONCE? Or that she doesn't want kids anymore? She was so on board with having kids, how could she change her mind so drastically and quickly?

I don't think they have enough of a foundation to keep going after this. They were off and on for so long then married for like two seconds before Amelia took off. Unfortunately, I think Owen should move on. He deserves to be happy, and I Just don't think Amelia is the person for him.

Jasmine: This Omelia situation is confusing to me. I get that they had to find a way to accommodatethe actress being pregnant, but this tension between them is too much. Many of us distinctly remember Amelia telling Owen about having a baby that died before, but now they're acting like that never happened.

I guess the issue now is that she's scared to have another baby again, or she doesn't want to have a baby, and she's scared to tell him that. I don't even know. It seems childish on her part, and I'm as confused as Owen is.

Do I like Omelia as a couple? Yes. Do I like them individually? Yes. But if Amelia continues with this, then I just need them to end it. We've been through watching Owen in a marriage that didn't work out, and I don't understand why this man can't find a compatible woman to make him happy.

His expectations are so low and yet he finds these amazing women who can't quite meet them.

Quotables for Week Ending February 10, 2017

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Eliza seems to be wearing down, and now she's insistent on pursuing Arizona. Do you like this potential ship?

Tiffany: I thought it had potential early on when they were subtly hinting at it. But the conversation last week felt so forced and out of the blue. Plus, does anyone think Arizona's standing up to Minnick because she's scared of falling in love with her? I mean, really?

Jasmine: I agree. I was indifferent to the ship at first, but it had potential. Now it just feels ridiculous and forced. I don't see Arizona catching feelings for the woman who treats most of her friends, including Richard, like crap.

And I hate the idea of Arizona being paired up with the first lesbian/bi woman that shows up, just because they both like girls.

Catherine and Richard might finally have a showdown. Are you annoyed that Catherine won't admit she's behind Eliza replacing Richard?

Tiffany: I'm basically annoyed with everything Catherine does. But especially now that she's turned someone I actually like (Bailey) into an annoying, power driven, unreasonable, Catherine clone. I love Richard and never wanted them to end up together.

Jasmine: Haha! Yeah, I can agree with Tiffany. I'm annoyed with all things Catherine at the moment. I love Debbie Allen, but Catherine can be a pain. I don't understand w
hy she hasn't come right out with it.

And I almost fell over laughing at her reprimanding April for butting into her marriage, like she didn't and still doesn't do the exact same thing with Jackson and April.

Grey's Anatomy Promo: "It Only Gets Much Worse"

What's your favorite scene and/or quote from the episode?

Tiffany: I liked Jo going to the house to make sure Alex wasn't in prison. It reminded me of the bomb episode in season 2 when Derek stopped by just to see that Meredith was still alive. Both Jo and Derek heard the news from other people but had to see for themselves because they loved the person so much.

It's also similarly heartbreaking in that neither Derek nor Jo think they should be with that person. Grey's is great with little throwback moments like that.

Jasmine: I LOVED Mer, Maggie, and Alex sitting on the bed and sharing food. I love their little family that they have formed. I could watch an entire episode of just Alex and his "sisters" dealing with life and running a household. I also loved that it was classic Grey's.

Do you agree with our round table? Let us know below!

You can watch Grey's Anatomy online right here via TV Fanatic!

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Jasmine Blu is a staff writer for TV Fanatic. Follow her on Twitter.

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Grey's Anatomy Round Table: Should Owen and Amelia Just End It? - TV Fanatic

Social and Behavioral Science Students Present Research to St. Gregory's Board of Directors – St. Gregory's University Athletics

Seniors preparing for graduation in the Department of Social and Behavioral Sciences presented their research to St. Gregorys Universitys Board of Directors as part of the boards February meeting. President Michael Scaperlanda invited six students to present their research posters to the board to highlight the work of St. Gregorys students. The intent was for board members to have direct interaction with the students they makes important decisions for.

I am glad that this happened, said Fr. Charles Buckley, OSB, who is a member of the board of directors and faculty member in the Department of Math and Natural Sciences. Board members spent half an hour circulating the room and asking students about their research.

This was a great opportunity for our students, said Dr. Vickie Jean, Department Chair of Social and Behavioral Sciences, One board member told me that this was what the mission of the university was all about, getting students to think critically about the big questions our society faces.

After presentations, board members attended midday prayers with the monks of St. Gregorys Abbey and had lunch with St. Gregorys students before taking up important discussions about the future of the university.

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Social and Behavioral Science Students Present Research to St. Gregory's Board of Directors - St. Gregory's University Athletics

Woodall students earn top honors at science, engineering fair – Muskogee Daily Phoenix

The 2017 Cherokee County Science & Engineering Fair took place on Feb. 7 at the Cherokee Community Center in Tahlequah. Seventeen Woodall students won or placed with projects involving original research in science, math, computers, or engineering.

Eighth-grade student Tristan Walters earned the Senior Division Grand Prize Award and 1st place in the Chemistry category with his project titled "Does Temperature Affect the Bioluminescence of Fireflies?"

Woodall eighth-grader Rylee Hunt captured the Senior Division Runner-Up Award as well as first place in the Behavioral Science group with research called "How Does Your Beauty Measure Up?"

Seventh-grade student Maycee Young's project "Dog or Cat Lover?" earned 3rd in the Senior Division Behavioral Science group, and eighth-grader Bindie Copeland's research called "Segments of Imagination" was 2nd Place in Environmental Science.

Eighth-grade student Ty Brant placed third in Math & Computers with his work involving computer programming, and seventh-grade Woodall student Jordan Hayes won the category with a project called "M & M Math."

Eighth grade and Senior Division participants Payton Smith won 1st Place in Earth & Space by researching water desalination; Betty Danner earned a 1st Place award in Medicine & Health by revealing the myth behind lactic acid; and Clayton Wallace was 1st in Zoology by presenting "Beef: It's What's for Dinner!"

Woodall seventh-grade students Gage Barnes (Broadhead Penetration) and Levi Troyer (The Tom Brady Effect) rounded out Woodall's Senior Division success by placing second and third respectively in the Physics category.

Sixth-grade student Ella Barnes presented the 1st place project in the Junior Division Behavioral Science category that attempted to answer the question of whether cell phone use hinders reaction ability or not. The Junior Division also had Woodall sixth-grade students Mikah Vann place 2nd in Earth & Space with "How To Use the Stars for Navigation"; Sydney Taylor in 2nd Place in Environmental Science with "Best Water Filtering System"; Jill Jarvis, 1st Place in Physics with "Popcorn: Are You Hot Enough To Pop?"; and Maddie Keys garnering 1st Place in the Zoology category with a project called "Mexican Jumping Beans are Living in My House!"

Also presenting their research due to their success at the Woodall science fair were Lane Taylor, Jagger Hall, Erica Cypress, Tyler Joice, Kenzie Snell, Lily Clark, Nate Brant and Linzi Woolard. Several Woodall students plan to participate in the Muskogee Regional Science & Engineering Fair on March 7-8.

Information: http://www.woodall.k12.ok.us/ or Dr. Geary Don Crofford, (918) 456-1581, gcrofford@woodall.k12.ok.us.

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Woodall students earn top honors at science, engineering fair - Muskogee Daily Phoenix

Metro MediSpa's Testosterone Therapy Benefits Men's Hearts – Military Technologies

WILMINGTON, NC, February 15, 2017 /24-7PressRelease/ Testosterone therapy has now been shown to be beneficial for older men knocking down the long-held assertion that it was detrimental to their hearts. Men can now regain their youthful vitality and ease the symptoms that accompany low testosterone levels.

What is Testosterone Therapy?

Hypogonadism is a disease in which the body is unable to produce normal amounts of testosterone due to a problem with the testicles or with the pituitary gland that controls the testicles. The symptoms of low testosterone include: loss of bone density and muscle mass, increased body fat, osteoporosis, diminished sexual drive, erectile dysfunction, anemia, frailty, depression, and coronary disease. Testosterone therapy is a way for men to improve the signs and symptoms of this disease. By opting for testosterone therapy, men can increase the amount of testosterone in their body up to sufficient levels.

Is it harmful to heart patients?

In the past, it was assumed that testosterone therapy posed potential health risks to men, like heart attacks and strokes. However, this is not true according to the latest research. The researchers at Intermountain Medical Center Heart Institute have presented a new study which deduces that testosterone therapy can help heart patients a great deal. The study shows that heart patients given testosterone therapy showed much better results than the patients not receiving the treatment.

The study further claims that the notion that testosterone therapy increases the risk of heart attacks and strokes is not correct. It discovered that heart patients who did not receive any testosterone therapy were 80% more likely to suffer a heart attack or stroke than the ones who received the therapy.

How was the study conducted?

The study involved 755 male patients suffering from heart disease ranging in age from 58 to 78, and tested the patients in groups of three. Each group was given testosterone therapy in the form of a gel or by injections, and their heart conditions were monitored for possible effects.

The results of this study are a significant leap in medical history. It concludes that contrary to the popular belief that testosterone therapy harms a mans heart, the use of this therapy can be improved or prevent heart disease. This study will help define further medical strategies related to heart conditions and problems. Now older men with low testosterone levels can be treated without fear of causing heart problems and allow them to continue active lifestyles.

Overall, our study suggests that what is best for mens health is to keep testosterone levels balanced and within a normal range, said Dr. Connie Odom.

ABOUT METRO MEDISPA Owned and operated by Connie Odom, M.D., Board Certified Anesthesiologist and American Academy of Anti-Aging Medicine Certified Physician. Metro MediSpa has changed the way cosmetic procedures are performed by introducing the first medically directed mobile spa in the Southeast.

Through anti-aging medicine along with advanced cosmetic treatments, our experienced team of medical professionals is committed to bring the beauty of an improved appearance and an inner age defying wellness to all.

Motivated by the belief that health and wellness affects all areas of ones life and having the knowledge in safe and effective cosmetic treatments, the staff at Metro Medispa can help people correct imperfections that had become uncomfortably noticeable.

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Antibody-Drug Conjugates: Catalysts for Chemistry – Genetic Engineering & Biotechnology News

Antibody-drug conjugates (ADCs), also known as armed antibodies, are positioned to be a significant source of next-generation oncolytic therapies. There has been explosive growth in ADC R&D, especially since the development and subsequent marketing approval of Mylotarg (gemtuzumab ozogamicin; withdrawn from market in 2010), Adcetris (brentuximab vedotin), and Kadcyla (ado-trastuzumab emtansine). Estimates place the global ADC market at $10 billion annually after 2024 with seven to 10 new commercial ADC launches projected in the next decade.

ADCs marry the selective targeting properties of antibodies with the potency of highly cytotoxic small molecules. The antibody targets and adheres to a selected antigenic cell-surface receptor, ideally only expressed on the target cancer cell. Once an ADC binds to its target cell, the cell internalizes the ADC through endocytosis, and the cytotoxic payload is then released in the lysosomal cellular compartment to provide precise, selective delivery to cancerous cells.

The development of ADCs brings many challenges, however. Multiple disciplines across drug development must engage to successfully discover, develop, evaluate and eventually manufacture a therapeutically relevant ADC. To illustrate, large macromolecular ADCs have a complex architecture whose assembly, manufacture, and analysis presents challenges for organizations without significant experience in biological conjugation, optimization, and the development of the payload-linker (PL; a component used for antibody attachment and subsequent release of the small molecule payload).

For many companies, outsourcing this component of ADC development may make sense. In this article, we will focus on the complexities of developing ADCs with an emphasis on the nature of the PL.

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Antibody-Drug Conjugates: Catalysts for Chemistry - Genetic Engineering & Biotechnology News

LA Galaxy continue to make steady progress during preseason: "The team chemistry is building" – LA Galaxy

CARSON, Calif. Steady progress continues for the LA Galaxy as the five-time MLS Cup champions prepare for a visit to Santa Barbara, where they will take on Armenian side Alashkert FC in a closed-door scrimmage on Saturday at Westmont College.

The Galaxy are coming off a week in which they played their first two matches of the preseason, a 1-1 tie with Club Tijuana last Tuesday at StubHub Center and a 1-0 loss to the San Jose Earthquakes last Saturday in Las Vegas.

Head coach Curt Onalfo said the team is improving as he envisioned.

I think every time you play a game the next week, the training gets sharper, he said Tuesday. I think today was a good example of that. I think were getting better each day and the team chemistry is building well also.

Now its about fine-tuning and utilizing the remaining games to continue to get match-fit, get sharper make sure our movements keep getting better.

There are some pieces missing French midfielder Romain Alessandrini still is awaiting a work visa and Gyasi Zardes is recovering from a knee injury but Onalfo has liked what he has seen from a team that underwent a number of off-season changes.

Onalfo admitted he and his staff will face some tough roster decisions prior to the regular-season opener on March 4 at home against FC Dallas. The Galaxys final preseason match is scheduled for Saturday, Feb. 25 against Portland at StubHub Center.

Everybodys showed well in making the job difficult, he said. Its just a matter of seeing how the rest of the preseason goes and making those final decisions.

Jermaine Jones, one of the teams biggest off-season additions, said the Galaxy will have a new look, but that may not be such a bad thing.

I would say last year the Galaxy was always the team with the names Gerrard, Keane, Dos Santos is still here, he said. I think this year theres not one player we try to push out and make the focus on him. You could have three main players, but it doesnt mean you win championships.

Its important we trust each other and believe that we can make something possible. I think thats the most important thing. I see the team is hungry. You want to prove people wrong, that a younger team with maybe not the names wins championships.

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Kings Daily: Chemistry feeds 3 frenzy – Sacramento Bee (blog)


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Distinguished FSU chemistry professor named fellow of Royal Society of Chemistry – Florida State News

Naresh Dalal, Robert O. Lawton Professor of Chemistry

A Florida State University chemistry professor has been named a fellow of the prestigious Royal Society of Chemistry in the United Kingdom.

Professor Naresh Dalal, a 22-year veteran of the FSU Department of Chemistry and former department chair, was named a fellow of the society in recognition of his accomplishments in the field of information storage and materials science.

Its just an honor, and Im humbled by this, Dalal said. This honor recognizes our contributions on an international level. And it obviously has a lot to do with my students over the last 35 years who have helped execute much of this work.

Dalal came to Florida State in 1995 from West Virginia University, drawn partly to the university because of the National High Magnetic Field Laboratory. Dalal used the MagLab to develop new magnetic materials that can be used for electronic information storage. Notably, he led a team that synthesized a material called Fe8 a molecule made of eight iron ions that form a high magnetic field. That substance led to new kinds of medical imaging.

In 2012, he was named a Robert O. Lawton Professor, the highest honor given by Florida State University faculty members to one of their own.

His current research involves the development of novel materials for information storage both electronically and magnetically, leading potentially to more compact and sophisticated components for future technology.

Professor Dalals recent research is notable in two respects, said Robert O. Lawton Professor of Chemistry and Biochemistry Alan Marshall.First, unlike most senior scientists, he is moving in directions quite different from his earlier work, and second, his recent research is among his best. In other words, he is still peaking.

Dalal said his selection as a fellow is also a tribute to his former colleague and friend, the late Sir Harold Kroto. Kroto was a Nobel Prize winner in chemistry who came to FSU in 2004 as the Francis Eppes Professor of Chemistry. He died last year.

Dalal was chair of the Department of Chemistry when FSU recruited Kroto, and Kroto, who was a former president of the Royal Society of Chemistry, had urged Dalal to become a member and seek nomination as a fellow.

Being a part of this organization in a way is me being thankful to him, Dalal said.

Dalal received his doctorate from the University of British Columbia. He is a fellow of the American Association for the Advancement of Science, American Chemical Society and American Physical Society.

Tim Logan, chair of the FSU Department of Chemistry, said Dalal being named a fellow is a fitting tribute to his career.

Being elected as a fellow of the Royal Society of Chemists is a well-deserved recognition of Nareshs outstanding career, Logan said. We are very fortunate to have scientists of his caliber here at FSU.

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Katherine Heigl is only one of the elements of ‘Grey’s Anatomy’ the creators of ‘Doubt’ brought to CBS legal drama – Los Angeles Times

When Greys Anatomy" executive producers Joan Rater and Tony Phelanleft the ABC medical soap to launch their own legal drama, they knew there was at least one aspect of the former series that they wanted to carry over to the new one: the sense of never knowing who is going to come through the door.

Doubt, the new CBS procedural from the wife-and-husband team, is set in a New York boutique law firm that takes on risky social justice cases.

Like in 'Grey's, you never know who will come in needing help, Phelan said. We wanted a show about people who were from various socioeconomic backgrounds. That was really important to us.

The series, which premieres Wednesday, stars Katherine Heigl as Sadie Ellis, a defense attorneywho becomespersonally involved with her latest case and client,played by Steven Pasquale (Rescue Me). The cast is rounded out by Elliott Gould, the chief of the law firm, and Laverne Cox, Dule Hill, Dreama Walker and Kobi Libii, all of whom play lawyers. Cox, it merits noting, is the first-ever transgender actor to play a transgender character in a series regular role on broadcast TV.

Doubt is somewhat inspired by ABCs late 90s-early 00s legal drama, The Practice, which Rater and Phelan devotedly watched early in their relationship.

We really enjoyed watching that show, Rater said, sitting next to her husband at a hotel bar in Pasadena on a recent weekday.We wanted to see more criminal defense lawyers; we wanted to get to know the defendants more...

Doubt attempts to explore the best and worst of the criminal justice system, looking at those who are criminalized and those who are committed to defending them. The imperfections of Americas penal system is an area of focus in which Hollywood has shown growing interest. In addition to HBOs 2016 limited seriesThe Night Of, a number of projects out of Sundance this year also investigate the imperfections of law and order.

The more we can see that people who are in prison are people with families and with dreams and aspirations, I think, is enlightening, Phelan said. Are we, as a country, really about reform and rehabilitation? Or are we about putting people away and throwing away the key and just getting them out of society? And if we are about that, let's just be honest about that. But if we are really about reform and rehabilitation, how do we do that?

The main case to which viewers are introduced involves Billy Brennan (Pasquale), a plastic surgeon who is facing conviction for the first-degree murder of his former girlfriend, who was killed two decades prior. Things grow complicated as the relationship between Billy and Ellisbecomes more intimate.

A similar attorney-client progression in The Night Of came under fire, with critics chiding it as a misguided development.Phelan and Rater say there's something to be said about that kind of intimacy.

The lawyers almost become a lifeline, so inmates develop this, sort of, dependence, Rater said. Sadie knows everything about Billy. They've spent all of this time together and they're both flawed in similar ways. They both have strange upbringings and we and the writers just thought that was interesting. It's a line you are not supposed to cross but the 'what if' of it all How would you negotiate it? How would you deal with the fact that it's so wrong and so taboo and what are the consequences? --is really interesting to us.

Doubt was originally developed for the 2015-16 season, but the pilot was never ordered to series. After undergoing re-development and re-casting (KaDee Strickland and Teddy Sears were replaced with Heigl and Pasquale), its now making it to air with a 13-episode order. It marks a reunion of sorts Phelan and Rater last worked with Heigl when she starred on Greys Anatomy. (Heigl left the series in 2010.)

It was nice just to continue our collaboration because we've known Katherine for 10 years now, Phelan said.

It was just the sort of the magic ingredient that the show needed, Rater said.

The most-read Entertainment stories this hour

yvonne.villarreal@latimes.com

Twitter: @villarrealy

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Katherine Heigl is only one of the elements of 'Grey's Anatomy' the creators of 'Doubt' brought to CBS legal drama - Los Angeles Times

Anatomy of a heart attack | Peacehealth | goskagit.com – goskagit.com

HEART ATTACKS HAPPEN to both women and menbut they dont always look the same. Theyre not as obvious as youd see on TV, and thats true for more women than men.

Heres a look at what makes recognizing a heart attack so importantand why noticing more subtle signs is especially important for women.

What to look for

What does a heart attack feel like? Chest pain or discomfort is the most common symptom for both women and men. The pain may last a few minutes or come and go. Some people say it feels like pressure, squeezing, or fullness. Or it may feel like an upset stomach or heartburn.

But women are more likely than men to have other heart attack signs, says Paul Connor, MD, PeaceHealth Medical Group Cardiology, in Bellingham.

Those may include:

Shortness of breath with or without chest pain

Nausea, lightheadedness, or vomiting

Unexplained fatigue that may last for days

Back, shoulder, arm or jaw pain

Women are also at higher risk for silent heart attacks, according to some studies. This is when symptoms of a heart attack are so mild that they go unnoticedor are dismissed as anxiety.

Silent heart attacks are just as dangerous as more obvious heart attacks, though, says Dr. Connor. Left untreated, they can cause scarring and permanent damage, raising the risk of other heart problems.

So dont be too quick to dismiss shortness of breath or lightheadedness as just anxiety. And make sure you tell medical professionals that you think youre having a heart attack, not an anxiety attack.

A supply problem at the pump

Despite womens more subtle symptoms, the mechanics of a heart attack are fundamentally the same for both sexes. It happens when the hearts blood supply is reduced or cut off, most often when an artery becomes blocked.

What usually sets the stage? Doctors call it atherosclerosis. It happens when arteries that bring blood to the heart slowly become clogged with plaque. A blood clot can form around these plaques, causing complete obstruction of the blood flow to the heart muscle.

Without prompt treatment, areas of heart muscle may die and eventually be replaced by scars. This damage could leave a heart attack survivor with a weakened heart.

And a weak heart may not be able to pump blood to the bodys organs like it should, which could result in other quality-of-life issues, Dr. Connor says.

Quick treatment can restore blood flow to the heart and help prevent damage. So be aware of these warning signs for both yourself and others. If theres even a slight chance you could be having a heart attack, dont wait. Call 911 and get to a hospital to give your heart the best chance.

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Anatomy class teaches several lessons – Seguin Gazette: Editorials – Seguin Gazette-Enterprise

Recently, a group of high school students, under the direction of anatomy teacher Daniel Sanchez visited Vogel Elementary and taught all of the second grade students a little lesson.

The subject a human cell.

While this may seem a little outside the younger students realm of understanding, the teens delivered the lesson in a way the youngsters could understand.

Prior to the visit, Sanchez, wanted to make sure his students understood the lesson and tasked them with writing a childrens story.

By using the terminology and definitions, his students received an easier way to remember what they have learned.

What he didnt expect to happen was to see that lesson evolve beyond his classroom, and spill over into the elementary classroom.

As Sanchez students read their stories to the second graders, the children eagerly listened and then asked questions.

They also got to see what a human cell looks like thanks to the models the teens also created for their class, unknowing that it would become a prop for this special session.

Not only did the high school students learn, but they taught their younger counterparts, solidifying what they learned.

They became role models for the younger students, and helped them engage in conversations.

They created a new curiosity for science, and quite possibly an interest that can lead to things beyond what they imagined.

Our Voice is the opinion of the Seguin Gazette editorial board.

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Scientists create mouse that resists cocaine’s lure – Medical Xpress

February 13, 2017 A diagram showing synapses in the reward circuit of mice when exposed to cocaine: on left, a normal mouse, and on right, a mouse with increased levels of cadherin. Credit: University of British Columbia

Scientists at the University of British Columbia have genetically engineered a mouse that does not become addicted to cocaine, adding to the evidence that habitual drug use is more a matter of genetics and biochemistry than just poor judgment.

The mice they created had higher levels of a protein called cadherin, which helps bind cells together. In the brain, cadherin helps strengthen synapses between neurons - the gaps that electrical impulses must traverse to bring about any action or function controlled by the brain, whether it's breathing, walking, learning a new task or recalling a memory.

Learning - including learning about the pleasure induced by a stimulant drug - requires a strengthening of certain synapses. So Shernaz Bamji, a Professor in the Department of Cellular and Physiological Sciences, thought that extra cadherin in the reward circuit would make their mice more prone to cocaine addiction.

But she and her collaborators found the opposite to be true, as they explain in an article published today in Nature Neuroscience.

Dr. Bamji and her collaborators injected cocaine into mice over a number of days and immediately placed in a distinctly decorated compartment in a three-room cage, so that they would associate the drug with that compartment. After several days of receiving cocaine this way, the mice were put into the cage and allowed to spend time in any compartments they preferred. The normal mice almost always gravitated to the cocaine-associated compartment, while the mice with extra cadherin spent half as much time there - indicating that these mice hadn't formed strong memories of the drug.

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To understand that unexpected result, Dr. Bamji and her associates in UBC's Life Sciences Institute analyzed the brain tissue of the genetically engineered mice.

They found that extra cadherin prevents a type of neurochemical receptor from migrating from the cell's interior to the synaptic membrane. Without that receptor in place, it's difficult for a neuron to receive a signal from adjoining neurons. So the synapses don't strengthen and the pleasurable memory does not "stick."

"Through genetic engineering, we hard-wired in place the synapses in the reward circuits of these mice," says graduate student Andrea Globa, a co-lead author with former graduate student Fergil Mills. "By preventing the synapses from strengthening, we prevented the mutant mice from 'learning' the memory of cocaine, and thus prevented them from becoming addicted."

Their finding provides an explanation for previous studies showing that people with substance use problems tend to have more genetic mutations associated with cadherin and cell adhesion. As studies such as this one illuminate the biochemical underpinnings of addiction, it could lead to greater confidence in predicting who is more vulnerable to drug abuse - and enable people to act on that knowledge.

Unfortunately, finding a way of augmenting cadherin as a way of resisting addiction in humans is fraught with pitfalls. In many cases, it's important to strengthen synapses - even in the reward circuit of the brain.

"For normal learning, we need to be able to both weaken and strengthen synapses," Dr. Bamji says. "That plasticity allows for the pruning of some neural pathways and the formation of others, enabling the brain to adapt and to learn. Ideally, we would need to find a molecule that blocks formation of a memory of a drug-induced high, while not interfering with the ability to remember important things."

Explore further: Molecular underpinnings of addiction produce strong addiction-related memories

More information: Cadherins mediate cocaine-induced synaptic plasticity and behavioral conditioning, Nature Neuroscience, nature.com/articles/doi:10.1038/nn.4503

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(Medical Xpress)A team of UBC neuroscientists has found that synapses that are too strong or 'sticky' can actually hinder our capacity to learn new things.

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Scientists at the University of British Columbia have genetically engineered a mouse that does not become addicted to cocaine, adding to the evidence that habitual drug use is more a matter of genetics and biochemistry than ...

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The anatomy of an energy crisis a pictorial guide – RenewEconomy

What energy crisis?

Who could forget the energy crises that affected electricity supply across south-eastern Australia last year.

Firstly the Tasmanian crisis, following the Basslink outage in December 2015. With hydro storage dams at record lows following a drought on the back of aggressive storage withdrawals during the carbon tax years, Tasmania enforced drastic measures to ensure supply. Thankfully, flooding winter rains, together with the eventual restoration of Basslink in June helped resuscitate the apple isles energy supply. Tasmanias hydro storages now stand at around 40% of full capacity, more than double at the same time last year.

Tasmanian hydropower storage capacity shows a strong seasonal trend, filling in winter rains, and drawing down during the summer and early autumn. Exchanges with Victoria via Basslink help provide security of supply, that was compromised by the outage in December 2015, when storages were already dangerously low on the back of the drought conditions in 2015 and aggressive draw down of storages during the Carbon-tax years to capitilise on the higher mainland spot prices.

July saw the first of the sequence of crises in South Australia that followed from, and were in many eyes, attributable to the closure of its last coal-fired power plant at Port Augusta in May of 2016.

With gas prices at record highs, and South Australia effectively isolated from Victoria due to upgrades on the main interconnector into Victoria, spot prices sky rocketed, culminating on a cold, windless winter day on July 7th. Energy consumers that had not contracted supply were at the whims of traders. Prices averaged over $1400/MWhour for the day and around $520/MWhour for the week, almost 800% above the average for that time of year.

Graphical summary of electrical power generation, demand, spot prices in, and exchange between, each of the five regions comprising the National Electricty Market. The period shown is the week of July 3rd- 9th, 2016, during the first South Australian energy crisis. Over the week, interconnector flows from Victoria into South Australia were restricted to an average of 225 MW, or about 40% of full capacity due to upgrade works. On July 7th, at the height of the crisis, the flow was limited to 166 MW. VWP = volume weighted price in $/MWhour. TOTAL.DEMAND = regional demand in MW. DISPATCH.GEN = regional generation in MW. NETINTERCHANE = net exports (positive) or imports (negative) in MW.

All that was superseded by the events of September, when extreme winds played havoc with the South Australian transmission system, toppling transmission lines in the mid north. Poorly understood default control settings automatically disconnected wind farms, leading to the interconnector tripping and a state-wide black out. Unanticipated problems in restarting the system exacerbated the pain.

Finally, failure of a transmission line in south-west Victoria on December 1 lead to a power loss at the aluminium smelter in Portland. The damage to frozen pot lines has jeopardised the smelters ongoing viability. As the states largest energy consumer and the one of the biggest regional employers, the political fallout is intense.

With 2016 very much the National Electricity Markets (NEM) annus horibilus, pundits awaited the summer of 2017 with bated breath. The combination of high gas prices, frighteningly intense summer heat, a fragile and ageing energy supply system, and increasing concerns about market rules, the scene was set for interesting times. Whatever was to transpire it was always going to be inflamed by political point-scoring the one commodity that seems rarely in short supply.

And so it would prove to be, even in the northern states of Queensland and New South Wales that had hither-too largely escaped the wrath of Electryone.

The summer of 2017 has seen extraordinary rises in spot prices beset the NEM, particularly in New South Wales and Queensland. Further blackouts in South Australia, and market interventions to avert them in New South Wales, have done little to assuage concern that our electrical power system is no longer fit for purpose. So far, 2017 Queensland spot prices have been around 400% above the historical average for this time of year.

Graphical summary of NEM operations for the period 1st January 11th February 2017.

With the summer far from finished, our politicians remain hard at it, pointing fingers and apportioning blame, doing almost anything and everything but that which is in most short supply namely, embracing bipartisanship. A glimmer of hope is to be found in comments from Chief Scientist Alan Finkel, who has been charged to lead a review of the security of our National Electricity Market.

To provide some guide to what is happening to the NEM, and why, I have compiled a few pictures that illustrate elements its basic anatomy. This is designed as background. In following posts in this series I will focus on the details of recent events that have so heightened the political heat.

The NEM comprises five interconnected regional jurisdictions one for each state along the eastern seaboard and South Australia. For each region, the market operator AEMO runs a 5-minute interval, energy-only, dispatch pool, or spot market. The objective is to balance supply with demand in a way that minimises cost, based on the bids submitted by generators. It is a complicated process. Settlement prices are aggregated at half hourly intervals, and determined as the average of bid prices of the last offer needed to meet the demand for the dispatch interval.

Pictorial of the generation structure on the NEM, as of early 2017. The top half shows the five regions comprising the NEM, the bottom half the power as generated and dispatched by fuel type progressing from fossil on the left through to renewables of the right. For the period shown (1/1/2017-11/2/2017) black coal contributed 55.6% of supply (at a capacity factor of 68%), brown coal 22.7% (cf=79%), natural gas 11% (cf = 24%), hydro 5.4% (cf = 14%) and Wind 4.6% (cf=29%) Units are in MW. Note that gas is the only fuel source common to all regions, but its contribution varies significantly from over 50% in South Australia, to just a few percent in Victoria. It is important to note that the small-scale distributed solar PV on domestic rooftops is not dispatched to the NEM and so is not included in this graphic. The installed capacity of around 5 GW of small scale solar PV contributed about an average of 700-800 MW across 2016.

With the focus of the dispatch pool being least cost electricity supply, AEMO also operates several ancillary markets to ensure the requirements for safe grid operation are met. This includes the provision of reserve supply and frequency control normally sourced from synchronous generators such as large coal plants.

AEMO also has regulatory powers to intervene in the market by demanding generation be made available in cases when the total bid capacity is insufficient. When demand exceeds total capacity, or if the available capacity cannot be made available in a timely fashion, AEMO can authorise load-shedding, effecting a re-balancing of demand to meet the available generation capacity.

Normally, large electricity consumers will contract power supply via the contract market, rather than directly through the spot market. This insures consumers against the potential for extreme price volatility allowed on the spot market, that can see prices range from between -$1000 and $14,000/MWhour. For comparison, the standard domestic retail tariff is about $250/MWhour or $0.25/kWhour.

The bid strategies of power plants reflect differences in their cost structures and performance characteristics. For example, fuel costs for brown coal generators are very low, but they are best operated at constant load. In contrast gas plants are generally much more rampable, but much higher cost. In Victoria, as a consequence gas is used almost exclusively to meet peaks in demand as illu
strated in the three graphics below.

Dispatch in Victoria for the period 8/2/2017-10/2/2017, coloured by fuel source. Also shown is the Victorian demand (brown line), available generation bid into the market (top black line), and net exports as negative (bottom black line)

Brown coal power generation in Victoria for the period 8/2/2017-10/2/2017, coloured by power station.

Natural gas generation in Victoria for the period 8/2/2017-10/2/2017, coloured by power station.

Typically a large base-load generator, such as a brown coal plant, will bid much of its capacity into the spot market at their short run cost, to ensure a slice of the action. In contrast peaking power plants will bid at price well above marginal cost, anticipating that they will required only very occasionally. Forward contracts of various kinds help insure revenue streams for base load generators against spot prices below their long-term cost of production, and for peaking plants being available when needed.

Renewables such as wind dispatch at the whims of the weather, and because of negligible short run marginal costs, bid their output at very low prices. As a price taker, wind generation tends to drive spot prices lower, impacting the viability of other generators. As shown below, and to be discussed in more detail in a following posts, the recent events in South Australian dispatch highlights the challenges in the market when wind power output correlates poorly with demand.

Dispatch in South Australia for the period 8/2/2017 through 10/2/2017, coloured by fuel source. Also shown is the South Australian demand (brown line), available generation bid into the market (top black line), and net imports (bottom white line). Black outs on the 8th February occurred when local dispatch curve hit the available generation. At that time here was no more capacity ready to be dispatched, so AEMO instigated load-shedding. (Note that not all capacity in South Australia was bid into the market at this time.)

Finally, rooftop PV is not dispatched onto the grid, but rather is revealed to the market as a reduction in demand.

In theory, the spot market is designed to encourage a competition that ensures prices provide generators with a revenue stream that is linked to their long run marginal cost of production. If prices do depart, competitive market principles should ensure system re-balancing either through investment in new generation or the withdrawal of old. Of course, competition needs to be provided by an adequate diversity in ownership.

And so shifts in the spot prices, signalled via the contract markets, are designed to reflect the balance of demand and supply. The years 2009-2014 were characterised by persistent reductions in demand across the NEM, in part due to growing penetration of solar PV. At the same time, the addition of new wind farms to meet Renewable Energy Target contributed to a growing oversupply in the market, reflected in very subdued spot prices. For example from 2010-2014, Victorian spot prices averaged about $35/MWhour, after factoring out the carbon tax. While that price is above the cost of production for existing Victorian brown coal generators, it would be well nigh impossible to obtain financing for any new large scale generation at prices less than about 2-3 times that.

Since 2014, demand has risen in Queensland due in part to the commissioning of new LNG gas processing facilities at Curtis Island. Reductions in generation capacity in Victoria and South Australia due to closure and/or mothballing of several fossil plants (Anglesea in Victoria and Northern and Pelican Point in South Australia), has significantly tightened the supply-demand balance. Consequently, spot prices are on the rise across the NEM.

Spot prices averaged about $60/MWhour across last year, but vary somewhat by region and by season.

As shown in diagrams above the make-up of generation in each of the five regions varies considerably, leading to different cost structures. Similarly differences in demand profiles lead naturally to differences in generation fleet. Finally there are differences in market competition.

With limited interconnection capacity, along with differences in regional demand and generation portfolios, occasionally lead to large separation in spot market prices. In times of very high demand during summer heat waves and winder cold snaps, or in times when supply is constrained by infrastructure (power plant or transmission) outages or fuel supply/cost issues, spot prices can be extremely volatile.

Historically, South Australia has had the highest prices and Victoria the lowest. This reflects the much higher proportion of gas in the generation mix, its larger proportional daily/seasonal cycle between minimum and maximum demand and, arguably, competition issues. As illustrated below, peak demand in South Australia is over 250% higher than the median, compared to around 150% in Queensland. A greater relative proportion of peaking generation capacity means higher average spot prices. Competition is a particular issue in South Australia, since the closure of the Northern Power Station, as it is in Queensland.

It is important to realise that while the physical characteristics of any power system are governed by the laws of physics, the market itself is a construct just one of many ways of matching supply and demand. In particular as an energy-only pool , there are questions about how well our NEM is suited to meeting the need of providing a cost effective, secure and environmentally acceptable energy supply. In particular, there is very little incentive for demand side management. Moreover, the power system does not operate in isolation, and needs to be considered with other policy settings in the gas and water markets as well as climate policy. In the following posts in this series I intend to address some of these issues with examples drawn from our recent experience on the NEM.

Source: The Conversation. Reproduced with permission.

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‘Grey’s Anatomy’, ‘How To Get Away With Murder’ And ‘Scandal’ Are All Renewed – Konbini

Good news for Shondaland, its three main series are all renewed and expected next fall. ABC is obviouslyvery confident in Shonda Rhimes work. Her fans will be able to continue to follow the difficult daily lives of three strong women: Meredith Grey, Olivia Pope and Annalise Keating.

(Photo: Konbini)

While How To Get Away With Murder has seen a drop in ratings since its debut, the two other series keep decent numbers. Greys Anatomy is particularly impressive when you consider the show is entering its 13th season. And yet, the medical drama always manages to renew itself with fresh storylines that are always great and perfectly melodramatic.

An adaptation of Romeo and Juliet entitled Still Star-Crossed is also expected but has yet an official release date. But, considering how little people are talking about the project, its unlikely it will last long on ABC.

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'Grey's Anatomy', 'How To Get Away With Murder' And 'Scandal' Are All Renewed - Konbini