Author Archives: ev1

Longevity gene may lead to 'molecular fountain of youth'

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Washington, Feb 1 (ANI): A new study has made a major advance in the understanding of the molecular mechanisms behind aging, providing new hope for the development of targeted treatments for age-related degenerative diseases.

Researchers were able to turn back the molecular clock by infusing the blood stem cells of old mice with a longevity gene and rejuvenating the aged stem cells' regenerative potential.

The biologists found that SIRT3, one among a class of proteins known as sirtuins, plays an important role in helping aged blood stem cells cope with stress. When they infused the blood stem cells of old mice with SIRT3, the treatment boosted the formation of new blood cells, evidence of a reversal in the age-related decline in the old stem cells' function.

"We already know that sirtuins regulate aging, but our study is really the first one demonstrating that sirtuins can reverse aging-associated degeneration, and I think that's very exciting," said study principal investigator Danica Chen, UC Berkeley assistant professor of nutritional science and toxicology.

"This opens the door to potential treatments for age-related degenerative diseases," Chen noted.

Notably, SIRT3 is found in a cell's mitochondria, a cell compartment that helps control growth and death, and previous studies have shown that the SIRT3 gene is activated during calorie restriction, which has been shown to extend lifespan in various species.

To gauge the effects of aging, the researchers studied the function of adult stem cells, which are responsible for maintaining and repairing tissue; it is a function that breaks down with age. They focused on hematopoietic, or blood, stem cells because of their ability to completely reconstitute the blood system, the capability that underlies successful bone marrow transplantation.

The researchers first observed the blood system of mice that had the gene for SIRT3 disabled. Surprisingly, among young mice, the absence of SIRT3 made no difference. It was only when time crept up on the mice that things changed. By the ripe old age of two, the SIRT3-deficient mice had significantly fewer blood stem cells and decreased ability to regenerate new blood cells compared with regular mice of the same age.

What is behind the age gap? It appears that in young cells, the blood stem cells are functioning well and have relatively low levels of oxidative stress, which is the burden on the body that results from the harmful byproducts of metabolism. At this youthful stage, the body's normal antioxidant defenses can easily deal with the low stress levels, so differences in SIRT3 are less important.

"When we get older, our system doesn't work as well, and we either generate more oxidative stress or we can't remove it as well, so levels build up. Under this condition, our normal antioxidative system can't take care of us, so that's when we need SIRT3 to kick in to boost the antioxidant system. However, SIRT3 levels also drop with age, so over time, the system is overwhelmed," said Chen.

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Longevity gene may lead to 'molecular fountain of youth'

Vaults of Terra Space Marine Biology Implantation – Video

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Vaults of Terra Space Marine Biology Implantation
Vaults of Terra returns with a look into the Space Marine implantation process that turns us weed humans into the super human Adeptus Astartes. Intro Music: Daniel Yount - Dark Times The Legal Notice: All works used in this video (Images, audio etc) belong to their respective authors, Vaults of Terra hold No propriety interest, either wholly or in part, in any of the work displayed here (This statement does not include the audio recorded by the Vaults of Terra). Games workshop, Warhammer 40000, Warhammer, 40k, Space Marine Etc are all Trademarks of Games Workshop Ltd. Games Workshop does not endorse or support the Vaults of Terra videos, they are independently made and moderated. All views opinions expressed in this video belong to the hosts and in no way reflect the views or opinions of Games Workshop Ltd.

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Vaults of Terra Space Marine Biology Implantation - Video

The Protein Klotho Paves The Way For Future Multiple Sclerosis Drugs

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Editor's Choice Academic Journal Main Category: Multiple Sclerosis Also Included In: Alzheimer's / Dementia Article Date: 31 Jan 2013 - 11:00 PST

Current ratings for: The Protein Klotho Paves The Way For Future Multiple Sclerosis Drugs

5 (2 votes)

As people begin to age the levels of Klotho in the brain also begin to decrease. They published their findings online in Journal of Neuroscience.

Multiple sclerosis (MS) is a condition in which the myelin inside the brain and spinal cord becomes damaged, causing demyelination. This can cause the nerve cells in the brain to communicate inefficiently; this can lead to serious physical and cognitive disability.

Signs and symptoms of MS usually begin to appear in young adults; it is more prevalent among women.

The earliest signs of MS begin when the immune system attacks the protective myelin. The researchers found that the Klotho protein is able to produce the necessary proteins vital for the production and maintenance of a healthy myelin, which could reverse the damage caused by MS.

In an abstract in the journal authors said:

We found significant effects of Klotho on oligodendrocyte functions, including induced maturation of rat primary oligodendrocytic progenitor cells (OPCs) in vitro and myelination."

Lead author, Carmela Abraham, PhD, added: "These results taken together indicate that Klotho could become a drug target for multiple sclerosis and other white matter diseases, including AD."

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The Protein Klotho Paves The Way For Future Multiple Sclerosis Drugs

Toxins out, ‘superfoods’ in for year-round health

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Some of you may have heard of juice cleanses and detox diets, and you may have even attempted one or another with varying success.

Beyonc gained notoriety when she lost weight drinking a combination of lemonade and cayenne pepper a tactic most health care professionals wouldnt recommend and the health market is saturated with seven-day green juice cleanses and smoothies that can be expensive and aim to help promote weight loss and rid the body of all sorts of toxins.

Superfoods

Avocados, which are high in vitamin C, thiamine and riboflavin. Beans, which contain B vitamins, calcium and potassium. They also contain folate, which helps maintain a healthy brain. Berries, including strawberries, blueberries, blackberries and raspberries, which are full of antioxidants that scientists believe help prevent and repair the stress that comes from oxidation, a natural process that occurs during normal cell function. Dairy-free chocolate, in moderate amounts, which elevates mood, lowers blood pressure and improves blood flow. Make sure the dark chocolate is at least 70 percent cacao. Cruciferous vegetables, which are high in fiber, vitamins and minerals and include broccoli, Brussels sprouts, cabbage, cauliflower, chard, kale, mustard greens, rutabagas and turnips. Spinach, a rich source of iron that has vitamins A and C. Walnuts, which have a large dose of omega 3 acids and the gamma-tocopherol form of vitamin E thats good for the heart.

Beneficial herbs and tea

Lemongrass works as an antifungal and antibacterial agent, as well as a diuretic and fever reducer. It also can settle upset stomachs and ease digestive problems. Cinnamon has been used as medicine throughout the world and can be used to fight colds and relieve indigestion and cramps. Rose contains many essential vitamins and can be used to detoxify kidneys. It is high in vitamin C and can calm the nerves. Lavender can be used to treat insomnia and restlessness. Jasmine tea can reduce the effects of free radicals and can be calming. Mint is known to soothe the stomach and peppermint helps stimulate digestion. Source: the Tea Smith

Recipes

Cleansing Vegetable Broth This powerful cleansing recipe not only cleans toxins from the body but also replenishes minerals in the body with its rich content of potassium and magnesium. It originates from India and is attributed to an Ayurvedic doctor. These leafy greens are also full of vitamin C, higher in beta-carotene than carrots and richer in iron and calcium than spinach.

Serves 8-10 1 bunch Swiss chard, chopped 1 bunch kale, chopped 1 bunch mustard greens, chopped head white cabbage, chopped 1 bunch dandelion greens, chopped 1 cup Brussels sprouts, chopped 1 large daikon radish, diced 1 bunch watercress, chopped 4 ounces kombu or wakeme seaweed 6 dried shiitake mushrooms 2 cloves garlic, crushed 2 leeks, sliced 1 fennel bulb, chopped 1 4-inch piece fresh ginger, peeled and chopped 1 teaspoon ground star anise 1 teaspoon ground turmeric 1 bunch fresh parsley, chopped 1 bunch fresh cilantro, chopped Chicken stock, as needed, optional Red chili flakes, optional

Put all of the ingredients into a large stockpot and fill it with enough water to cover vegetables but at least 2 inches below the rim of pot. Set the pot over medium-high heat and bring to a boil; reduce the heat to medium-low and simmer for one hour. Using a mesh strainer, remove the vegetables and set aside. Continue cooking the broth for an additional 15 minutes to strengthen the flavor and reduce slightly. Let the broth cool completely in the pot before transferring to glass jars. Store in the refrigerator for up to one week, or freeze in airtight plastic containers for up to one month. Reheat before serving. For cleansing and detoxification, consume 3 cups per day. Note: If you want to use the cooked vegetables, working in batches, puree them in a food processor or blender with just enough chicken stock to liqueify them and then transfer the puree to a saucepan. Heat over medium-low heat until warmed; ladle into bowls and garnish with chili flakes. Serve immediately. Recipe courtesy Dr. Maos Secrets of Longevity Cookbook, by Dr. Mao Shing Ni

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Toxins out, ‘superfoods’ in for year-round health

Dr. Carter of Atlanta, GA has been named a Patients' Choice Award Winner for 2012

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ATLANTA, Jan. 30, 2013 /PRNewswire-USNewswire/ -- Among the select few physicians honored with the prestigious Patients' Choice Award this year is Dr. Michael Carter.

(Photo: http://photos.prnewswire.com/prnh/20130130/DC51286)

In fact, of the nation's 870,000 active physicians and dentists, just five percentconsistently received top scores from their patients on sites like Vitals (http://www.vitals.com), qualifying them for this honor in 2012.

Millions of patients go online each year to rate their doctors on various components of care, including accuracy of their diagnosis, the amount of time they spent with the doctor, and the doctor's bedside manner and follow-up care. Patients' Choice reviews these rankings and other quality measures to compile its yearly list of award winners.

Dr. Michael Carter commented on the recognition: "I'm so honored to receive an award that's based on how my patients view the quality of care I provide. I strive each day to exceed my patients' expectations, and I'm grateful that they've recognized my efforts."

About Michael Carter: a short profile by and about the honoree: Dr. Michael Carter is a board certified physician with a special focus on providing preventative medicine and minimally invasive cosmetic surgery. He is a member of: American Academy of Cosmetic Surgeons, American Academy of Liposuction Surgeons, American Academy of Anti-Aging Medicine. Dr. Carter's focus is treating the entire body of the patient. In addition to being a skilled cosmetic surgeon, Dr. Carter emphasizes testing and the natural treatment of out of balance body organs that are most responsible for weight gain, fatigue, depression, gastrointestinal problems and female hormonal imbalances.

For more information on this Patients' Choice Award winner, please visit Dr. Michael Carter's profile on PatientsChoice.org.

Following the publication ofMichael Carter 's selection for thePatients' Choice Award,American Registry seconded the honor and addedDr. Carterto The Registry of Business Excellence. An exclusive recognition plaquehas been designed to commemorate the honor. The doctor's customwall plaque is shown here.

For more information on Dr. Michael Carter , located in Atlanta , GA , please call 770-450-0846, or visit http://www.atlanta-liposuction.com.

This press release was written by American Registry, LLC with approval by and/or contributions from Dr. Carter and was distributed by PR Newswire, a subsidiary of UBM plc.

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Dr. Carter of Atlanta, GA has been named a Patients' Choice Award Winner for 2012

Copy of PHYSIOLOGY; THE MENSTRUAL CYCLE by Professor Fink – Video

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Copy of PHYSIOLOGY; THE MENSTRUAL CYCLE by Professor Fink
Review of the Menstrual Cycle. The Lecture includes a review of the anatomy of the female reproductive system, ovarian follicles, follicle cells, corpus luteum and corpus albicans, the role of the Pituitary Gland, the 28-day cycle, Follicle Stimulating Hormone (FSH), Luteinizing Hormone (LH), the Preovulatory (Follicular) Phase, the Postovulatory (Luteal) Phase, LH surge and ovulation, estrogen, progesterone, endometrium, menstruation, pregnancy and Human Chorionic Gonadotropin (HCG). Reference is made to the Ovulation Test Kit, Chorionic Sac, Pregnancy Test Kit, Basal Body Temperature, Rhythm Method, Menopause, amenorrhea and Fertility Drugs.

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Copy of PHYSIOLOGY; THE MENSTRUAL CYCLE by Professor Fink - Video

OMICS Group-Biochemistry

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OMICS Group-Biochemistry Physiology Open Access-2168-9652-1-103
OMICS Group is an Open Access publication model that enables the dissemination of research articles to the global community. Thus, all articles published under Open Access can be accessed by anyone.

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OMICS Group-Biochemistry

Koko FitClub Introduces Koko Fuel Custom Nutrition

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BOSTON, Jan. 31, 2013 /PRNewswire/ -- On Feb. 4, Koko FitClub, the state-of-the-art workout centers with the patented Smartraining automated personal training system, launches Koko Fuel, an integrated nutrition program that builds individually customized, nutritionist-recommended, online meal plans for members at all its 120 locations nationwide.

(Logo: http://photos.prnewswire.com/prnh/20130131/AQ51673LOGO)

Koko Fuel is the third element of the Koko Smartraining system that includes strength and cardio regimens designed for each member's unique goals and fitness level. The visionary KoKo FitClub workout centers are known for their commitment to helping members build healthy lifestyles upon a foundation of lean muscle with highly efficient, personalized fitness regimens that offer the benefits of a 90-minute workout in just 30 minutes.

Koko Fuel was developed by a team led by top nutritionist Debra Wein, MS, RD, LDN, CWPD. The program is not a diet, but rather provides research-based nutritional guidance and online meal plans to burn fat, build lean muscle and "Fuel" each member's personal Smartraining workouts.

"Koko Fuel completes the Koko Smartraining experience with a sound, evidence-based nutrition program designed to help members build and preserve their body's foundation of precious lean muscle," said Koko FitClub President and co-founder Mary Obana. "We founded this company on the belief that through technology, we can help change lives with a simpler, faster, more effective path to fitness, and Koko Fuel is the next step in doing that."

To get started with Koko Fuel, Koko FitClub members will consult with their club's FitCoach, who will help select a fitness goal and intensity level. The member's profile is then loaded onto a key that contains the member's individual workout data that integrates with the Koko Fuel plan and is tracked on the member's personal online portal at http://www.mykokofitclub.com.

"It's no secret that being fit and healthy requires a combination of healthy eating and exercise, but no one has ever integrated the two like Koko FitClub does," said Koko FitClub Chief Fitness Officer Michael Wood, CSCS. "No one else in the world can offer this holistic, simple path to success in a customized, automated fitness system like we do."

For locations and membership information, go to http://www.kokofitclub.com.

About Koko FitClub

The first Koko FitClub opened in Boston in 2008 as an efficient, lean-muscle-building alternative to traditional gyms, and today has more than 120 company-owned and franchise FitClubs in 30 states. Its name, Koko, inspired by the Japanese word for individual, refers to Koko FitClub's fully customized fitness and nutrition programs that make up the patented Koko Smartraining System. The Smartraining System is automated personal strength and cardio training, offering the benefits of a 90-minute workout in just 30 minutes, combined with Koko Fuel, the program's integrated nutritional component. In 2012, the company received a Franchise Business Review Franchisee Satisfaction Award and this year was named to the 2013 Entrepreneur Magazine Franchise 500.For more information, go to http://www.kokofitclub.com, http://www.youtube.com/user/KokoFitClubChannel or http://www.facebook.com/KokoFitClub.

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Koko FitClub Introduces Koko Fuel Custom Nutrition

School nutrition professionals go beyond the daily lunch menu

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By Paulette Lash Ritchie, Times Correspondent Paulette Lash RitchieTampa Bay Times In Print: Thursday, January 31, 2013

BROOKSVILLE The Hernando County School Nutrition Association is a group of about 150 members and is the local branch of the National School Nutrition Association.

"It's a professional organization that supports the endeavors of school food service professionals," said Lori Drenth, the Hernando County School District's food and nutrition services director.

"We try to do things locally to support and show the public that school nutrition professionals care about students and what goes on in our community," Drenth said. "We do fundraisers. We do yard sales (and) pasta sales to raise funds to support graduates interested in food service or nutrition fields."

The group has also recently been selling cookbooks.

Students interested in the scholarship opportunity can apply through their guidance counselors or culinary arts teachers. Drenth said the organization tries to award at least two $500 scholarships a year. Past recipients, she said, wanted to attend the famed culinary school Johnson and Wales, go into medicine or even biochemistry.

Besides providing scholarships through fundraising, Drenth said, the association sponsors training and professional certification in nutrition, safety and sanitation. The Florida School Nutrition Association puts out a publication, and the local groups contribute to the "Chapter Chatter" section.

The association's president is Fran Thomas, Chocachatti Elementary food and nutrition services assistant manager. The president-elect, who takes office July 1, is Beverly Dube-O'Looney, a Winding Waters K-8 food nutrition assistant. The treasurer/secretary is Winding Waters K-8 food and nutrition services manager Jackie Nelson. The certification chairwoman is Diana Bartlett, West Hernando Middle School food and nutrition services assistant manager.

The scholarship committee coordinator is Jennifer Patrick, Moton Elementary's food and nutrition services assistant manager. Patti White is the chapter reporter for the Florida Food Services publication; she is Fox Chapel Middle School's food and nutrition services manager. Carol Monroe, a West Hernando Middle School food nutrition assistant, collects dues.

Drenth is the local chapter's adviser.

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School nutrition professionals go beyond the daily lunch menu

Science Should Be a Story: Tyler DeWitt at TEDxBeaconStreet – Video

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Science Should Be a Story: Tyler DeWitt at TEDxBeaconStreet
When new friends tell Tyler DeWitt that they hated science classes in school, he doesn #39;t blame them. In this video, Tyler discusses how modern science education has taken a fascinating subject filled with riveting stories, colorful characters, and spectacular demonstrations, and has eviscerated it of its joy, excitement, and intellectual engagement. Science communication should be a narrative, he argues, that draws on analogies, metaphors, humor, and emotional connection. Tyler puts these ideas into action by telling a fun, intriguing story that explains the complex means by which viruses attack their targets. He urges fellow scientists to dispense with jargon, seriousness, and tyrannical technical precision, and to focus on communicating their main ideas through appealing narratives. Tyler DeWitt has taught high school Biology, Chemistry, and English in independent schools in the United States and South Korea, and he has worked as a project manager to develop new K12 science curriculum for the state of Florida. Tyler is currently a Ph.D. candidate in Microbiology at MIT. He has served as a fellow with the Education Foundation of America #39;s Teaching for Experience program, and at MIT he is a National Science Foundation Fellow and a Graduate Resident Tutor. In thespirit of ideas worth spreading, TEDx is a program of local, self-organized events that bring people together to share a TED-like experience. At a TEDx event, TEDTalks video and live speakers combine to spark deep ...

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Science Should Be a Story: Tyler DeWitt at TEDxBeaconStreet - Video