Biomolecules Biology 1
Biomolecules Biology 1

By: youthpastor33

Read more:
Biomolecules Biology 1 - Video

Energy in Cells Biology 1
Energy in Cells Biology 1

By: youthpastor33

Link:
Energy in Cells Biology 1 - Video

Plant Defense AP Biology
Plant Defenses for AP Biology

By: youthpastor33

Read the rest here:
Plant Defense AP Biology - Video

Feb. 3, 2013 By reproducing in the laboratory the complex interactions that cause human genes to turn on inside cells, Duke University bioengineers have created a system they believe can benefit gene therapy research and the burgeoning field of synthetic biology.

This new approach should help basic scientists as they tease out the effects of "turning on" or "turning off" many different genes, as well as clinicians seeking to develop new gene-based therapies for human disease.

"We know that human genes are not just turned on or off, but can be activated to any level over a wide range. Current engineered systems use one protein to control the levels of gene activation," said Charles Gersbach, assistant professor of biomedical engineering at Duke's Pratt School of Engineering and member of Duke's Institute for Genome Sciences and Policy. "However, we know that natural human genes are regulated by interactions between dozens of proteins that lead to diverse outcomes within a living system.

"In contrast to typical genetics studies that dissect natural gene networks in a top-down fashion, we developed a bottom-up approach, which allows us to artificially simulate these natural complex interactions between many proteins that regulate a single gene," Gersbach said. "Additionally, this approach allowed us to turn on genes inside cells to levels that were not previously possible."

The results of the Duke experiments, which were conducted by Pablo Perez-Pinera, a senior research scientist in Gersbach's laboratory, were published on-line in the journal Nature Methods. The research was supported by the National Institutes of Health, the National Science Foundation, The Hartwell Foundation, and the March of Dimes.

Human cells have about 20,000 genes which produce a multitude of proteins, many of which affect the actions of other genes. Being able to understand these interactions would greatly improve the ability of scientists in all areas of biomedical research. However because of the complexity of this natural system, synthetic biologists create simple gene networks to have precise control over each component. These scientists can use these networks for applications in biosensing, biocomputation, or regenerative medicine, or can use them as models to study the more complex natural systems.

"This new system can be a powerful new approach for probing the fundamental mechanisms of natural gene regulation that are currently poorly understood," Perez-Pinera said. "In this way, we can further the capacity of synthetic biology and biological programming in mammalian systems."

The latest discoveries were made possible by using a new technology for building synthetic proteins known as transcription activator-like effectors (TALEs), which are artificial enzymes that can be engineered to "bind" to almost any gene sequences. Since these TALEs can be easily produced, the researchers were able to make many of them to control specific genes.

"All biological systems depend on gene regulation," Gersbach said. "The challenge facing bioengineering researchers is trying to synthetically recreate processes that occur in nature."

Share this story on Facebook, Twitter, and Google:

See the rest here:
Synthetic biology: Recreating natural complex gene regulation

Public release date: 4-Feb-2013 [ | E-mail | Share ]

Contact: Robin Crawford src@faseb.org 301-634-7010 Federation of American Societies for Experimental Biology

Bethesda, MD The Federation of American Societies for Experimental Biology (FASEB) announces the opening of registration for the Science Research Conference (SRC): Ciliate Molecular Biology.

The 2013 FASEB Conference on Ciliate Molecular Biology is a unique forum for researchers who study Ciliates as model organisms, to share their recent results. Current work using Ciliates is making important contributions to a large number of fields including the role of small RNAs in chromatin modification and genome regulation, cytoskeletal architecture and dynamics, membrane traffic, a range of evolutionary issues, telomerase structure and function, and the assembly and maintenance of cilia and basal bodies.

Other key roles of the Conference include disseminating recent technological developments in working with Ciliates, and exploring the use of Ciliates in innovative educational programs. The attendees, who come from laboratories throughout the world, include established researchers in the field as well as scientists who are just beginning to explore Ciliates as model systems, in addition to postdocs, and both graduate and undergraduate students.

FASEB SRC has announced a total of 34 SRCs in 2013. To register for an SRC, view preliminary programs, or find a listing of all our 2013 SRCs, please visit http://www.faseb.org/SRC.

###

Since 1982, FASEB SRC has offered a continuing series of inter-disciplinary exchanges that are recognized as a valuable complement to the highly successful society meetings. Divided into small groups, scientists from around the world meet intimately and without distractions to explore new approaches to those research areas undergoing rapid scientific changes.

In efforts to expand the SRC series, potential organizers are encouraged to contact SRC staff. Proposal guidelines can be found at http://www.faseb.org/SRC.

Original post:
FASEB SRC announces conference registration open for: Ciliate Molecular Biology

Public release date: 4-Feb-2013 [ | E-mail | Share ]

Contact: Robin Crawford src@faseb.org 301-634-7010 Federation of American Societies for Experimental Biology

Bethesda, MD The Federation of American Societies for Experimental Biology (FASEB) announces the opening of registration for the Science Research Conference (SRC): Biology of Cilia and Flagella.

The 2013 Biology of Cilia and Flagella Conference is an important and unique scientific conference where basic and translational research intersect to drive rapid advances in the field of cilia/flagella and human ciliopathies. The underlying theme of the 2013 conference is the intriguing dance between basic research in model systems and clinical research in human disease syndromes. This conference will provide a venue for intense scientific discussion of recent advances in cilia and flagella biology and foster collaborations between researchers from around the world interested in basic, clinical, and developmental relevance of the cilium.

###

FASEB SRC has announced a total of 34 SRCs in 2013. To register for an SRC, view preliminary programs, or find a listing of all our 2013 SRCs, please visit http://www.faseb.org/SRC.

Since 1982, FASEB SRC has offered a continuing series of inter-disciplinary exchanges that are recognized as a valuable complement to the highly successful society meetings. Divided into small groups, scientists from around the world meet intimately and without distractions to explore new approaches to those research areas undergoing rapid scientific changes.

In efforts to expand the SRC series, potential organizers are encouraged to contact SRC staff at SRC@faseb.org. Proposal guidelines can be found at http://www.faseb.org/SRC.

FASEB is composed of 26 societies with more than 100,000 members, making it the largest coalition of biomedical research associations in the United States. FASEB enhances the ability of scientists and engineers to improvethrough their researchthe health, well-being and productivity of all people. Our mission is to advance health and welfare by promoting progress and education in biological and biomedical sciences through service to our member societies and collaborative advocacy.

Read this article:
FASEB SRC announces conference registration open for: Biology of Cilia and Flagella

Public release date: 4-Feb-2013 [ | E-mail | Share ]

Contact: Robin Crawford, CMP src@faseb.org 301-634-7010 Federation of American Societies for Experimental Biology

Bethesda, MD The Federation of American Societies for Experimental Biology (FASEB) announces the opening of registration for the Science Research Conference (SRC): Glucose transport: Gateway for Metabolic Systems Biology.

The 2013 FASEB Science Research Conference "Glucose transport: Gateway for Metabolic Systems Biology" is a unique conference where the role of glucose transport in the control of cellular growth and proliferation, and of whole organism metabolic homeostasis, are explored through formal talks, posters and discussions in an informal setting conductive to scientific interaction.

Sessions spanning from atomic mechanisms of glucose transport to systems biology of energy metabolism will be delivered by experts from around the world, and chaired by experienced, leading investigators in each field. An important theme of this conference will be the impact of glucose metabolism research on medically relevant problems such as type 2 diabetes and cancer. To insure timely discussion of emerging information, approximately 30% of the program will be chosen from submitted abstracts.

###

FASEB SRC has announced a total of 34 SRCs in 2013. To register for an SRC, view preliminary programs, or find a listing of all our 2013 SRCs, please visit http://www.faseb.org/SRC.

Since 1982, FASEB SRC has offered a continuing series of inter-disciplinary exchanges that are recognized as a valuable complement to the highly successful society meetings. Divided into small groups, scientists from around the world meet intimately and without distractions to explore new approaches to those research areas undergoing rapid scientific changes.

In efforts to expand the SRC series, potential organizers are encouraged to contact SRC staff at SRC@faseb.org. Proposal guidelines can be found at http://www.faseb.org/SRC.

FASEB is composed of 26 societies with more than 100,000 members, making it the largest coalition of biomedical research associations in the United States. FASEB enhances the ability of scientists and engineers to improvethrough their researchthe health, well-being and productivity of all people. Our mission is to advance health and welfare by promoting progress and education in biological and biomedical sciences through service to our member societies and collaborative advocacy.

Original post:
FASEB SRC announces conference: Glucose transport -- Gateway for Metabolic Systems Biology

Public release date: 4-Feb-2013 [ | E-mail | Share ]

Contact: Robin Crawford src@faseb.org 301-634-7010 Federation of American Societies for Experimental Biology

Bethesda, MD The Federation of American Societies for Experimental Biology (FASEB) announces the opening of registration for the Science Research Conference (SRC): The Biology of Calpains in Health and Disease.

The 2013 FASEB Science Research Conference on The Biology of Calpains in Health and Disease brings together investigators from a wide range of disciplines to focus on the biology of calpains and understanding and treating diseases that involve these proteins. The conference will cover a diversity of topics ranging from bioinformatics of calpain substrates, calpains and signal transduction, role of calpains in cell and tissue degeneration, and contributions of calpains to various disorders. In addition to invited speakers from around the world presenting cutting edge research, a feature of this meeting is "New and Notable" talks in which the most exciting abstracts will be selected to for platform presentations. This provides a forum for young investigators and will include the most current research in the field.

FASEB SRC has announced a total of 34 SRCs in 2013. To register for an SRC, view preliminary programs, or find a listing of all our 2013 SRCs, please visit http://www.faseb.org/SRC.

###

Since 1982, FASEB SRC has offered a continuing series of inter-disciplinary exchanges that are recognized as a valuable complement to the highly successful society meetings. Divided into small groups, scientists from around the world meet intimately and without distractions to explore new approaches to those research areas undergoing rapid scientific changes.

In efforts to expand the SRC series, potential organizers are encouraged to contact SRC staff. Proposal guidelines can be found at http://www.faseb.org/SRC.

FASEB is composed of 26 societies with more than 100,000 members, making it the largest coalition of biomedical research associations in the United States. FASEB enhances the ability of scientists and engineers to improvethrough their researchthe health, well-being and productivity of all people. Our mission is to advance health and welfare by promoting progress and education in biological and biomedical sciences through service to our member societies and collaborative advocacy.

Go here to see the original:
FASEB SRC announces conference registration open: The Biology of Calpains in Health and Disease

Public release date: 4-Feb-2013 [ | E-mail | Share ]

Contact: Robin Crawford src@faseb.org 301-634-7010 Federation of American Societies for Experimental Biology

Bethesda, MD The Federation of American Societies for Experimental Biology (FASEB) announces the opening of registration for the Science Research Conference (SRC): Biology and Chemistry of Vision.

Since its inception in 1985, the Biology and Chemistry of Vision FASEB Science Research Conference has been one of the premier and most successful meetings focused on photoreceptor biology. The upcoming 2013 meeting will highlight the most recent advances in a broad and diverse range of photoreceptor function issues.

This meeting brings together premier senior and junior investigators of different expertise to discuss pigment and retinoid turnover, the biochemistry and physiology of phototransduction, photoreceptor cell biology and development, synaptic transmission, and invertebrate vision, as well as vision disorders, animal models, and therapy. In keeping with the success in past meetings, the 2013 conference will continue to emphasize close and intense scientific interactions among the participants, especially between senior and junior investigators.

FASEB SRC has announced a total of 34 SRCs in 2013. To register for an SRC, view preliminary programs, or find a listing of all our 2013 SRCs, please visit http://www.faseb.org/SRC.

###

Since 1982, FASEB SRC has offered a continuing series of inter-disciplinary exchanges that are recognized as a valuable complement to the highly successful society meetings. Divided into small groups, scientists from around the world meet intimately and without distractions to explore new approaches to those research areas undergoing rapid scientific changes.

In efforts to expand the SRC series, potential organizers are encouraged to contact SRC staff. Proposal guidelines can be found at http://www.faseb.org/SRC.

FASEB is composed of 26 societies with more than 100,000 members, making it the largest coalition of biomedical research associations in the United States. FASEB enhances the ability of scientists and engineers to improvethrough their researchthe health, well-being and productivity of all people. Our mission is to advance health and welfare by promoting progress and education in biological and biomedical sciences through service to our member societies and collaborative advocacy.

Original post:
FASEB SRC announces conference registration open for: Biology and Chemistry of Vision