Grey’s Anatomy After Show Season 1 Episode 13 "I’m Winning" | AfterBuzz TV – Video


Grey #39;s Anatomy After Show Season 1 Episode 13 "I #39;m Winning" | AfterBuzz TV
AFTERBUZZ TV -- Grey #39;s Anatomy edition, is a weekly "after show" for fans of ABC #39;s Grey #39;s Anatomy. In this episode, host Jason Carter breaks down the episode...

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Grey's Anatomy After Show Season 1 Episode 13 "I'm Winning" | AfterBuzz TV - Video

UCI Team Discovers Bone Marrow Stem Cells’ Potential In Stroke Recovery

By Estel Grace Masangkay

Bone marrow stem cells may help in stroke recovery, according to a team of researchers from the University of California, Irvines Sue and Bill Gross Stem Cell Research Center.

Neurologist Dr. Steven Cramer and biomedical engineer Weian Zhao together analyzed 46 studies evaluating the use of a type of multipotent adult stem cells mostly processed from the bone marrow called mesenchymal stromal cells (MSC) in animal models of stroke. Results showed that MSCs were superior to control therapy in 44 out of the 46 studies.

Dr. Cramer said Stroke remains a major cause of disability, and we are encouraged that the preclinical evidence shows [MSCs] efficacy with ischemic stroke. MSCs are of particular interest because they come from bone marrow, which is readily available, and are relatively easy to culture. In addition, they already have demonstrated value when used to treat other human diseases.

The MSCs effect on functional recovery was shown to be robust regardless of other factors such as dosage, time of administration relative to the stroke onset, or administration method. An earlier report focusing on MSC mechanisms of action explained how the cells were attracted to the injury sites and began releasing a wide range of molecules in response to signals emitted by the damaged areas. The molecules in turn stimulate several activities including blood vessel creation for enhanced circulation, protection of vulnerable cells, brain cell growth, and others. The MSCs also fostered an environment conducive to brain repair.

We conclude that MSCs have consistently improved multiple outcome measures, with very large effect sizes, in a high number of animal studies and, therefore, that these findings should be the foundation of further studies on the use of MSCs in the treatment of ischemic stroke in humans, said Dr. Cramer.

The UCI teams analysis appeared in the April 8 issue of Neurology.

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UCI Team Discovers Bone Marrow Stem Cells' Potential In Stroke Recovery

New thinking on brain-science therapies could help foster kids

Therapies based on brain science and limited use of antipsychotic medications are the answer for thousands of foster kids whose traumatic childhoods have left them with depression and extreme aggression, according to a growing number of experts. Many children taking antipsychotic medications do not have psychosis but trauma-induced behavioral problems with symptoms that mimic mental illness, researchers and child advocates said.

Those symptoms are controlled through potent antipsychotics and antidepressants including Risperdal, Abilify and Zoloft, drugs sometimes prescribed to children for "off-label" reasons outside the realm of Food and Drug Administration recommendations.

Foster kids in 2012 were prescribed anti-psychotics at 12 times the rate of other children on government insurance, which has raised alarms that the drugs are overprescribed to a vulnerable group.

The drugs are among a broader class of mood-altering medications called psychotropics that are prescribed to more than one-quarter of the 16,800 foster children in Colorado. Antipsychotics are the most powerful of the group and have been linked to weight gain and diabetes in children, among other problems.

Momentum in the field of neurological, trauma-based therapies for children is building, and state child welfare programs including in Colorado are reacting by trying to reform their systems to make sure abused and neglected children are receiving appropriate therapy.

The progress is difficult to quantify, however. Colorado does not track how much it spends on trauma-focused therapies, but government insurance claims show the average annual Medicaid spending on psychotropic medications for foster children is $2,295 per child.

There is evidence in Colorado, though, that therapies focused on fixing developmental problems in children's brains caused by trauma are working.

At a Denver residential treatment center for children whose behavior is so explosive many were kicked out of foster homes, therapists try to change the way the kids' brains work and often with lower doses of medication than children were taking when they arrived. The average age of children at Mount Saint Vincent center is 9, and the average number of placements in the system by the time they arrive is six.

Most of the kids at Mount Saint Vincent, a former orphanage in northwest Denver, come full of psychotropic medications, some taking three or four at once to control their outbursts and settle their minds.

Soon after they arrive, consulting psychiatrists and therapists re-evaluate their dosages and try to lower them, sometimes switching to milder drugs from Risperdal to the more benign Clonodine, for example.

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New thinking on brain-science therapies could help foster kids

With the Help of Neurostimulation, Patient Voluntarily Moves Previously Paralyzed Muscles – Video


With the Help of Neurostimulation, Patient Voluntarily Moves Previously Paralyzed Muscles
Kent Stephenson, the second person to undergo epidural stimulation of the spinal cord at the University of Louisville in Kentucky, is shown here as he volunt...

By: Neurology Today

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With the Help of Neurostimulation, Patient Voluntarily Moves Previously Paralyzed Muscles - Video