Advances in assisted reproduction create more options and new legal issues for LGBT couples

PUBLIC RELEASE DATE:

1-Aug-2014

Contact: Sophie Mohin smohin@liebertpub.com 914-740-2100 Mary Ann Liebert, Inc./Genetic Engineering News

New Rochelle, NY, August 1, 2014Lesbian, gay, bisexual, and transgender individuals who want to conceive a child may face the same problems as some of their heterosexual and cisgendered peers, such as reduced fertility, but in addition they often face additional physiological and legal challenges to become parents. A comprehensive review of the most recent advances in assisted reproduction options is presented in the article "LGBT Assisted Reproduction: Current Practice and Future Possibilities," published in LGBT Health, a peer-reviewed journal from Mary Ann Liebert, Inc., publishers. Cutting-edge research and options likely to be available in the future are also discussed. The article is available free on the LGBT Health website.

A. Evan Eyler, MD, MPH, University of Vermont College of Medicine, Burlington; Samuel C. Pang, MD, Reproductive Science Center of New England, Lexington, MA; and Anderson Clark, PhD, a Reproductive Biologist from Boston, MA, discuss the many medical options available to the LGBT community. The authors provide expert commentary on topics such as gestational surrogacy, in vitro fertilization, donor egg banks, and techniques to preserve future reproductive capability for transgender individuals whose transition plan entails procedures that will, or are likely to, compromise their fertility. The article also explores important economic and legal implications of assisted reproduction.

"In the past, many people in the LGBT communities did not regard reproduction as a realistic option; however, social and scientific progress have changed that," says Editor-in-Chief William Byne, MD, PhD, Icahn School of Medicine at Mount Sinai, New York, NY. "Clinicians who work with LGBT-identified people, particularly transgender youths and their families, should familiarize themselves with the material covered in this interview. Future options may become available even for transgender youths who undergo pubertal suppression prior to the production of viable gametes."

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About the Journal

Spanning a broad array of disciplines LGBT Health, published quarterly online with Open Access options and in print, brings together the LGBT research, health care, and advocacy communities to address current challenges and improve the health, well-being, and clinical outcomes of LGBT persons. The Journal publishes original research, review articles, clinical reports, case studies, legal and policy perspectives, and much more. Complete tables of content and a sample issue may be viewed on the LGBT Health website.

About the Publisher

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Advances in assisted reproduction create more options and new legal issues for LGBT couples

This Could Be The Last Calendar App You Ever Install

This article contains an interview with Timeful CEO Jacob Bank and chairman Yoav Shoham.

A behavioral scientist, artificial intelligence professor, and Stanford PhD candidate in machine learning walk into an office. The result, strangely enough, is yet a to-do and calendar app. But it's no joke.

These three smart, uniquely qualified people--noted economist Dan Ariely, professor Yoav Shoham, and CEO Jacob Bank--arent in love with to-do apps. But with their app Timeful, theyre trying to solve an acutely modern human problem using the types of tools people are already used to.

We built many things that looked very different from a calendar and a to-do list, but what we found over and over again is that its hard to affect behavior change if youre not in the environment, says CEO Jacob Bank. Its very hard to get people to go to another place that adds functionality on top of a set of tools that theyre already accustomed to--like the calendar and to-do list. We eventually realized that to have an impact we had to leverage some of the familiarities of the current tools.

Timeful uses what the teams calls the "Intention Genome" and "Intention Rank" to algorithmically assist in scheduling a persons day. The names were inspired by Pandoras Music Genome and Googles Page Rank, respectively. The Intention Genome breaks down user behavior to better categorize it and the Intention Rank helps to determine the best place to schedule items throughout the day.

The Timeful app is essentially just a backdrop for the companys algorithmic magic. Sure, it looks like a smart to-do list and calendar, but thats the sleight of hand. Its real trick is trying to make people more mindful of their time and form better habits.

We needed a single starting point to demonstrate how algorithms and behavioral science can help people manage their time, and thats really around scheduling flexible things and getting them onto your calendar, explains Bank. Everything about the current app is about inputting the flexible things you need to do and well help you get them on your schedule. Everything that doesnt directly feed into that goal was cut from the app.

In addition to normal meetings and appointments users are encouraged to add things like drink water, walk, study, or a host of other positive tasks. These are all things that vie for a person's valuable time, but usually arent scheduled for specific times. The learning algorithm looks at the person's day and will suggest a time accordingly and let the user confirm or deny the suggestion as well as move it to a different time.

The app will learn from all the different interactions a user makes and decide when they are most productive. It makes sense to do the important and critical tasks when a person is at their most productive and scheduling mindless tasks for other times. As part of the settings theres a slider which allows the user to control how often scheduling suggestions are made.

Smart calendar apps arent new. Tempo and Mynd for example have been around for a while. Tempo includes clever features to connect with contacts, displaying drive times, and other social interactions. Mynd is a fairly similar to Timeful in the sense that both are trying to actively learn about the user. But Mynd includes a few more surface level features that go beyond scheduling a persons day.

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This Could Be The Last Calendar App You Ever Install

UW animal research oversight committees strive for consensus

Craig Berridge, a behavioral neuroscientist at the University of Wisconsin-Madison, is comfortable with the scrutiny given animal research on campus.

Animal research is a heavily regulated and overseen process, says Berridge, who studies the brain mechanisms of rats. And I think everyone who does animal research feels theyre balancing the need for and desire to alleviate human suffering and to minimize animal suffering.

Berridge is the chairman of the College of Letters and Science committee that oversees animal research. There are five such bodies, known as Institutional Animal Care and Use Committees, or IACUCs. Experiments are also vetted by funding agencies such as the National Institutes of Health.

These committees were mandated by a1985 amendment to thefederal Animal Welfare Act in the wake ofrevelations about the scandalously grisly laboratory conditions of a colony of rhesus monkeys in Silver Spring, Maryland.

Its a committee with a very explicitly identified purpose, Berridge says. Its a committee that satisfies federal rules, federal laws, and those laws prescribe what were supposed to do.

But others are skeptical that the animal researchers who dominate the IACUCs are capable of rigorously evaluating the ethics of the work on which their livelihoods and careers are built.

These are technocrats, says Rick Marolt, a local critic of animal experimentation. They live in a culture of animal experimentation.

The committees are primarily composed of animal researchers, although they are required to include at least one public member. They have the ability to reject studies or require changes. Usually, committees approve experimental protocols unanimously after requesting revisions.

Since 2004, around 12,000 protocol submissions have been made to the UWs five campus IACUCs, a somewhat duplicative number since many were submitted multiple times, says Eric Sandgren, director of the Research Animal Resources Center. Eighteen of those protocols drew dissenting votes, nine were denied outright, and an unknown number of protocols were simply withdrawn, he says.

Sandgrennotes that the committees almost always ask for protocol revisions. I do not believe it is a criticism of our system that IACUCs are willing to work with investigators until a protocol finally receives approval.

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UW animal research oversight committees strive for consensus

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Damning audit of Aboriginal Affairs shows a department thats deeply and intractably flawed

By John Ivison | nationalpost

Bernard Valcourt has been handed the political equivalent of the punishment meted out to Sisyphus, who was tasked with rolling an immense boulder up a hill in Hades for all eternity.

The Minister of Aboriginal Affairs not only has to appease 560 First Nations bands, who want more federal money and fewer conditions, he also has to take the rap for the worst department in government. It is an unenviable job. When the First Nations Education Bill unraveled, I remember saying that, after covering native affairs for a decade, Id reached the considered opinion that nothing of substance would ever be achieved. Ever.

Theres plenty of blame to pass around for this tragic state of affairs. In the specific instance of the Education Bill, critics and rivals of the then-Assembly of First Nations National Chief, Shawn Atleo, turned down the opportunity of a $1.9-billion injection into native education in order to settle personal vendettas. The deal with the federal government was endorsed by AFN executive committee members in December, who then turned around and abandoned Mr. Atleo in the spring. There is no harder job in Canadian politics than herding opinion among the fractious chiefs, each of whom thinks he or she is a head of state.

Aside from the particularly poisonous nature of First Nations politics, there are structural barriers to getting anything done. Many small First Nations have the responsibilities handled elsewhere in Canada by provinces, municipalities, school boards and health boards. They have too many politicians (a councillor for every 100 people), not enough expertise and a dependency culture that discourages enterprise.

But as a report card just sneaked on to the Aboriginal Affairs website in the dead of summer makes clear, the federal department charged with improving the lot of First Nations in this country bears a large measure of responsibility for the intractability of the First Nations predicament.

The department was evaluated on the use of performance measurement the collection of information to see whether results have been achieved. If it had been my sons report card, hed be grounded, without electronic stimulation, for a month. The department was measured on 10 criteria and got the equivalent of 2 Bs, 6 Cs and 2 Ds. The only reason Aboriginal Affairs is not at rock bottom and still digging is that the previous report two years ago was even more abysmal.

The report concluded that the department collects vast amounts of data that remains unanalyzed. Just this week, the governments First Nation Financial Transparency Act kicked in, with chief and councillor salary information trickling in from across the country. Dont get me wrong this is important information that should improve accountability on reserves. But its not clear what the department will do with the data once it has all been published on its labyrinthine website.

This apparent agnosticism in results-based management extends to cost-efficiency. Aboriginal Affairs spends $8-billion a year but the report makes clear that cost-effectiveness is not a top priority. A more pressing concern for staff is not to be held responsible for any outcomes that they dont control. The inevitable consequence is the construction of inflexible silos that dont interact. The departments culture remains focused on transactions, funding and outputs It lacks a comprehensive strategy to manage poor performance, the report concluded. In other words, the focus is on getting money out of the door there is no flexibility to see what is working and tailor programs accordingly.

Sheila Fraser, the former auditor general, noted some years back the most shocking thing about the plight of First Nations in this country is the lack of improvement. In an insightful paper on the subject, governance consultant John Graham blamed deep structural problems for the quagmire. As he pointed out, the Walkerton Inquiry heard that a minimum of 10,000 households is required to sustain a high quality provider of drinking water, yet many First Nations have just 600 people and manage their own water systems.

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Damning audit of Aboriginal Affairs shows a department thats deeply and intractably flawed