New Jersey’s oldest resident dies at 112 – The Philadelphia Tribune

ENGLEWOOD, N.J. New Jerseys oldest resident, who once claimed beer and whisky kept her spry, has died at the age of 112.

The Record of Bergen County reported that Agnes Fenton, of Englewood, N.J., died Thursday, Aug. 24, 2017, according to a caretaker Lamont Saunders, of Teaneck, N.J. Shes listed in Gerontology Wikis oldest living people in the U.S.

Fenton was born in Holly Springs, Mississippi, in 1905 and previously owned a restaurant in Tennessee.

She was one of the first black women to own a restaurant in the state.

Fenton had lived in Englewood since the 1950s, after she moved to the state with her second husband. He died in 1970.

Although she had no children, she remained active in the church community of St. Marks Church in New York throughout her life. She was looked after by neighbors, firefighters and Saunders, whose mother was a friend of Fentons.

Fenton was prescribed alcohol by a doctor for a benign tumor in 1943. She took heed, drinking Miller High Life and Johnnie Walker Blue Label daily for decades. When interviewed on her 110th birthday, Fenton credited the routine for her longevity. Old age eventually forced Fenton to quit drinking, Saunders said.

She said Fenton remained mentally sharp and while she might not remember whether she took her medication that day, she could recall any part of her life in detail.

Fenton always reminded those close to her of the importance of having God in their lives.

She was among 1,643 New Jersey residents who were at least 100 years old in 2010 280 men and 1,363 women, according to the U.S. Census Bureau. While their numbers are growing, centenarians made up a scant .02 percent of the population, or about one in every 5,350 state residents.

Fenton became the oldest living person in New Jersey when Adele Dunlap died at 114 in February.

Fentons unusual longevity garnered her both local and national attention. She was one of 360 to 600 people on the planet to become a supercentenarian, based on estimates by the Gerontology Research Group and the New England Centenarian Study at Boston University School of Medicine. A supercentenarian is someone who has reached 110 years.

At the time, Englewood proclaimed Agnes Fenton Day to celebrate her milestone birthday, and she received letters from the governor and President Barack Obama and first lady Michelle Obama to congratulate her.

At 105, she became part of a study of human longevity at Boston University Medical Center, was interviewed by Diane Sawyer and had a portrait painted by Ahmad Stokes, who painted President Obama.

Saunders said the funeral arrangements have not yet been finalized. (AP)

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New Jersey's oldest resident dies at 112 - The Philadelphia Tribune

As Tolstoy noted (sort of), all unhappy microbiomes are unhappy in their own way – UW Today

News releases | Research | Science

August 25, 2017

The bacterial communities that live inside each of our guts are relatively similar when times are good, but when stress enters the equation, those communities can react very differently from person to person.

This microbiological version of the Anna Karenina principle is a new paradigm suggested by scientists at the University of Washington Bothell and Oregon State University. It may suggest who would benefit most from screens to identify the microbes that reside in their gut, with implications for drug therapy, management of chronic diseases and other aspects of medical care.

On Aug. 24, the researchers published a perspective piece in Nature Microbiology outlining their adaptation of the Anna Karenina principle for the microbial realm. The principle gets its name from the opening line of the novel Anna Karenina by Leo Tolstoy: All happy families are alike; each unhappy family is unhappy in its own way.

It turns out that this observation applies to perturbed microbiotas of humans and animals. When these microbiotas are unhappy, each is unhappy in its own way.

This line of thinking started with studies of the microbiology of threatened corals, said lead and corresponding author Jesse Zaneveld, an assistant professor of biological sciences at UW Bothell. We found that several stressors made the types of bacteria on corals more variable, allowing blooms of different harmful bacteria on each coral.

We were struck by similarities to HIV/AIDs. After HIV suppresses the immune system, patients become vulnerable to opportunistic pathogens but you cant predict which one will infect any particular patient. It turns out that this microbial variation is a pattern common to many though certainly not all stressors and diseases, and occurs in helpful microbes as well as harmful ones.

Before joining the UW Bothell faculty, Zaneveld was a postdoctoral researcher at OSU, working with assistant professor of microbiology Rebecca Vega Thurber. It was there that they formulated the idea that microbial communities might behave more in line with Tolstoys words than scientists had previously thought.

When microbiologists have looked at how microbiomes change when their hosts are stressed from any number of factors temperature, smoking, diabetes, for example theyve tended to assume directional and predictable changes in the community, said Vega Thurber, who is also a corresponding author on the perspective. After tracking many datasets of our own we rarely seemed to find this pattern but rather found a distinct one where microbiomes actually change in a stochastic, or random, way.

Collecting a microbiome sample from a marine coral.Oregon State University

Zaneveld and Vega Thurber worked with OSU doctoral student Ryan McMinds to survey the academic and research literature on microbial changes caused by perturbation. They found those stochastic or random changes to be a common occurrence, but one that researchers have tended to discard or bury deep in supplementary materials, rather than highlight in their reports.

Whats amazing is how obvious these Anna Karenina principle effects are if youre looking for them and how easy they are to miss if youre searching for a more conventional pattern, said Zaneveld. When researchers have reported them, theyve often assumed that they are a unique quirk of the microbiology of their disease of interest, rather than a more general phenomenon.

Their work drew together diverse ideas and experiments from microbiome research including observations from humans and other animals and across multiple human diseases. They propose new methods for analyzing microbiome data to identify situations where the Anna Karenina principle might be at work.

When healthy, our microbiomes look alike, but when stressed each one of us has our own microbial snowflake,' said Vega Thurber. You or I could be put under the same stress, and our microbiomes will respond in different ways thats a very important facet to consider for managing approaches to personalized medicine. Stressors like antibiotics or diabetes can cause different peoples microbiomes to react in very different ways.

Humans and animals are filled with symbiotic communities of microorganisms that often fill key roles in normal physiological function and also influence susceptibility to disease. Predicting how these communities of organisms respond to perturbations anything that alters the systems function is one of microbiologists essential challenges.

Studies of microbiome dynamics have typically looked for patterns that shift microbiomes from a healthy, stable state to a dysbiotic, stable state; dysbiosis refers to any unusual configuration of the microbiome with negative consequences for the health of the host. By the Anna Karenina principle, the microbial communities of dysbiotic individuals vary more in composition than in healthy individuals.

The researchers found patterns consistent with Anna Karenina effects in other systems as well, such as the lungs of smokers. Since microbiomes also influence how patients respond to medical drugs, conditions that make the microbiome more variable such as inflammatory bowel disorders may also make more variable patients responses to drugs from digoxin to asprin.

But, to consider and test these possibilities, scientists must first discuss the Anna Karenina effect among themselves.

This is the start of a conversation, and not all diseases will show these patterns, said Zaneveld. But when you see the same pattern everywhere from corals enduring high temperatures to wild chimpanzees with suppressed immunity it suggests we should pay very close attention to the mechanisms that produce it.

I hope that by drawing together these research findings from diverse areas, we accelerate the development of common tools and language to understand the role of chance in shaping the microbial part of ourselves.

The research was funded by the National Science Foundation.

###

For more information, contact Zaneveld at 425-352-3789 or zaneveld@uw.edu and Vega Thurber at 541-737-185 or Rebecca.Vega-Thurber@oregonstate.edu.

Adapted from a press release by the OSU Office of News and Research Communications.

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As Tolstoy noted (sort of), all unhappy microbiomes are unhappy in their own way - UW Today

In pain? For some, gene studies could provide a quick cure – WRAL.com

Raleigh, N.C. Many people spend years searching for a diagnosis of a debilitating medical problem, paying for treatments or surgery that don't help. Now, researchers at UNC say that, for some, recent advances in genetic testing could fix their problems once and for all.

Elizabeth Davis, a local genes study participant, does not take walking for granted. For 30 years, she could barely walk at all. "When I was 6, I started walking on my toes," she said. "I started going to different doctors, trying to find out what it was."

The muscles in Davis' foot had tightened up, causing her pain. She needed crutches and, sometimes, a wheelchair. For years, the cause of her condition remained a mystery.

According to Dr. James Evans, a researcher at UNC's Center for Genetic Medicine, about 30 percent of patients find an answer to their problems when they participate in a genes study. Participants' blood samples are analyzed with the latest advances in DNA sequencing.

"The patients themselves typically seek us out because they've been looking for answers for a long time," said Evans. "There might not be a known treatment, so sometimes that answer doesn't really change their life significantly."

Davis saw positive results after participating in the study, and Dr. Jonathan Berg, an Assistant Professor of Genetics at UNC, was happy with the results. "Her case is an unusual one in that it just happened to be a condition that is exquisitely treatable -- with just a pill," said Berg.

The genes study discovered that Davis had a muscle rigidity problem similar to that of many people with Parkinson's Disease. Doctors learned that it was Dopa, a drug used by millions of Americans with the disease, could help Davis walk again.

"The relief was fast and just by taking a quarter of a pill," said Davis. "I overheard my oldest son telling his friend that 'his mom is not on crutches anymore.' I'll never forget him saying that."

The study, funded by the National Institutes of Health, has even bigger plans for the future. UNC researchers say they're planning a randomized controlled trial to see if these types of genetic tests can benefit patients in the long run and prove to be a cost-effective diagnostic test.

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In pain? For some, gene studies could provide a quick cure - WRAL.com

Philly native discusses the ‘Allure’ of anti-aging to movie star super-heroines – Philly.com

Allure magazine made headlines this past week when they announced that they will no longer use the term anti-aging in their stories.

This issue is the long-awaited, utterly necessary celebration of growing into your own skin wrinkles and all, said the magazine in its latest issue. No one is suggesting giving up retinol. But changing the way we think about aging starts with changing the way we talk about aging.

With that in mind, and starting with this issue, we are making a resolution to stop using the term anti-aging. Whether we know it or not, were subtly reinforcing the message that aging is a condition we need to battle think antianxiety meds, antivirus software or antifungal spray.

The issue for actresses, especially with movies featuring non-aging superheroes staying so popular, is how to stay relevant and in the game.

In the piece,Allure also included quotes from past and present stars like X-Men star Halle Berry, who is quoted as saying, When you see everybody around you doing it, you have those moments when you think, to stay alive in this business, do I need to do the same thing? I wont lie and tell you that those things dont cross my mind, because somebody is always suggesting it to me. You know, if you just did a little bit of this and that, lift this up, then this would be a little bit better. Its almost like crack that people are trying to push on you. Thats what I feel like. I just have kept reminding myself that beauty really is as beauty does, and it is not so much about my physical self. Aging is natural, and thats going to happen to all of us. I just want to always look like myself, even if thats an older version of myself. I think when you do too much of that cosmetic stuff, you become somebody else in a way.

Cate Blanchett (the upcoming Thor: Ragnarok), says in the article, I havent done anything, but who knows. When youve had children, your body changes; theres history to it. I like the evolution of that history; Im fortunate to be with somebody who likes the evolution of that history. I think its important to not eradicate it. I look at someones face and I see the work before I see the person. I personally dont think people look better when they do it; they just look different. Youre certainly not staving off the inevitable. And if youre doing it out of fear, that fears still going to be seen through your eyes. The windows to your soul, they say.

However, Philly native Ronald Klatz, who has been called the guru of anti-aging by Business Week and is the President of The Academy of Anti-Aging Medicine, said that Allure and the celebritieshave a misunderstanding of what anti-aging is.

First of all, let me applaud the 29 celebrities in the Allure magazine online article, for living or having lived a life that seems to be healthy and that adheres to anti-aging principles, said Klatz. These would include healthy eating, proper amount of exercise, likely buying natural foods and being blessed with great genetics.

Unfortunately, being blessed with great genetics alone does not always help someone stay beautiful as they circle the sun more than 40 times, he continued. You have to believe that, although age is inevitable, it is not the only factor that causes your body to deteriorate and grow older.

Look at Cindy Crawford, he added. I doubt very many seniors in high school would refuse to take Cindy to the prom! Even though she is blessed with better genetics than most of us, I am sure she engages in plenty of exercise to keep her body young and healthy and combat the effects of aging.

I certainly dont believe in unnecessary plastic surgery, hormonal therapies that are not supervised, or stem cell therapies at the beauty shop or overzealous and completely false claims by creams and other products that claim to beanti-aging, Klatz said. Anti-aging should not be a buzzword. Instead, I believe that credible non-commercial information should be used as a tool to combat ignorance and protect consumers.

Anti-aging is about living healthy and inner beauty, he added. It isnt about cosmetic surgery, solely enhancing our appearance or trying to live forever. It is about getting older with a better quality of life and slowing down and in some cases defeating disease.

While Klatz is pleased that Allure is acknowledging the issue, he said,Magazines such as Allurehardly focus on or promote inner beauty. They focus on outward appearance, pushing cosmetic goods, promote unbelievably attractive celebrities and models and then have the gall to take shots at botox for helping millions of people try to look and feel a little better.

Unfortunately, magazines like Allure give young women unrealistic expectations on a daily basis, Klatz concluded. They make people feel that they have to look like Halle Berry or Jennifer Aniston to be beautiful and thats simply not true! You just need to live an anti-aging lifestyle!

Published: August 24, 2017 9:17 AM EDT

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These Six Startups From Y Combinator’s Demo Day 1 Are Ready to Transform Our World – Futurism

A Room Full of Ideas

Great ideas,given the proper support, can change the world. Thats one of the reasons seed funding provider Y Combinator helps innovative startups acquire the financial resources they need to put their ideas into action. Since 2005, theyvefunded about 1,500 startups, and two times every year, they present some of those companies to investors via a three-day event known as Demo Day.

For the firstdayof Y Combinators Summer 2017Demo Day event, the startup accelerator presented 50 companies that all have remarkable potential. While you can check them all out on TechCrunch,the following six startups earn our vote as the most futuristic of them all.

Founded by a group of medical doctors and biomedical research scientists, Forever Labs combines two of the most advanced fields in modern medicine: stem cells and anti-aging research.

The startups current staff of 20 doctors wants to take a different approach to fighting age-related diseases by cryogenically freezing stem cells that can be used to combat such diseases when a person is older.

According to the company, stem cell storage couldgrow into a $56 billion market, and the figure doesnt seem outlandish considering the rapid pace at which anti-aging studies and stem cell research have been advancing lately.

Sunuisanother startup with a health-focus, only instead of combatting aging, their goal is to help those who suffer from visual impairments.

The company wants to help blind people navigate streets without having to depend on a cane or a guide dog. To do this, the startup has developed a sonar bracelet or smartwatch that vibrates to alert visually impaired people of nearby objects.

Sunu band combines sonar or echolocation with gentle precise vibrations to inform the user about objects or obstacles within their environment, according to the companys website. After beta-testing the device for six months, Sunu says it managed to reduce the chances that their vision-impaired users got into accidents by 90 percent.

Not all of the startups featured at Demo Day were focused on health and medicine, though this next one combines materials engineering withtextile science.

Kestrel Materialshas designed a fabric thats a step-up from breathable and waterproof types, and their goal is simple enough: reduce the need for bulky layers. To do this, the startup has created an adaptive material that reacts to cold and warmth.

When exposed to cold surroundings, the fabric flexes and creates air pockets that trap heat and keep people warm. During warmer weather, the air pockets collapse and prevent heat from being trapped in the clothing. Since the material uses common fibers, such as nylon and polyester, the applications for such an adaptive fabric are as plentiful as the styles of clothes people wear.

Few things scream future quite likeflying cars, and the next two startups are looking to extend their reach into that space.

First is Skyways, a startup based in Austin, Texas, thats building vertical take-off and landing (VTOL) delivery drones. While they arent exactly the kinds of flying cars you may expect to one day operate yourself, delivery drones like Skyways are positioned to be just as big a part of that flying future.

Skyways drones are capable of hauling loads of up to roughly 20 kilograms (45 pounds), and the company wants to use them to provide the military with a transportation service that doesnt put peoples lives at risk.

Now, this startup takes flying cars to the next level.

Pykawants to make autonomous single-person aircraft a part of our reality, and theyve already built a 181 kilogram (400 pound) one that can fly itself.

While theyre ironing out the tons of regulations requiredfor commercial use of this transportation system, Pykas taken on a side gig in New Zealand as an autonomous crop duster.

Speaking of autonomous tech and farming, thisstartup wants to employ robots as vegetable farmers.

Modular Science, as their name suggests, is into building modular machines for agriculture, and one of their products is a specialized plant-farming robot. The companys goal is to automate 99 percent of the vegetable farming process in the next six months.

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These Six Startups From Y Combinator's Demo Day 1 Are Ready to Transform Our World - Futurism

How Overcoming Demands on Attention Can Help Alleviate Poverty – Newswise (press release)

Newswise If the interest rate banks paid on customers deposits were to soar from 0.3 percent to 5 percent, you would expect that most people would start saving more. But, it turns out, most people arent that calculating.

In a recent field experiment in Chile, a large majority of people did not increase their savings in response to the higher interest rate. What did prompt them to save more? It was when their peers were watching. Savings almost doubled when the participants in the experiment announced their savings goals to a self-help group and had their progress publicly monitored.

It is just one example of how behavioral science can help policymakers spur changes that impede economic development around the world.

In the paper, Overcoming behavioral obstacles to escaping poverty, published in the journal Behavioral Science & Policy, University of Chicago Booth School of Business Assistant Professor Christopher Bryan and coauthors from several universities and development organizations, find policies aimed at serving the poor are more effective when they take into account the human tendency to procrastinate and the limits poverty puts on attention spans.

The scholars focus on two well-studied psychological phenomenapresent bias and limited attentionthat have wide ranging implications for international development policy.

Everyone has limited attentional bandwidth, but wealthy people, freed from having to spend this precious attention on acquiring food, shelter and other basics, have more attention available for handling unexpected hassles and making strategic decisions to improve their circumstances, the authors write.

Likewise, people often fail to expend small amounts of money, time or effort up front to obtain much larger benefits in the future. This human tendency towards present bias is common in rich and poor populations alike, but has a larger negative effect on people with low incomes.

The authors outline simple interventions that policymakers can take to overhaul international development policy with these behaviors in mind. Removing obstacles upfrontsuch as lowering upfront costs, simplifying or eliminating complicated paperwork, and timing the delivery of subsidies to correspond to when major payments (like school fees) will be dueimprove outcomes.

How does it work?

The bottom line here is that, by taking into account even just a couple of important behavioral principles, we can improve the effectiveness of many development programs and policiesoften dramatically, said Bryan. More exciting than that: we can often achieve those gains in effectiveness at little or no added cost once the policies are in place.

The other co-authors of the research are Nina Mazar, World Bank and University of Toronto; Julian Jamison, World Bank and Innovations for Poverty Action; Jeanine Braithwaite, University of Virginia; Nadine Dechausay, MDRC; Alissa Fishbane, ideas42; Elizabeth Fox, United States Agency for International Development; Varun Gauri, World Bank; Rachel Glennerster, Massachusetts Institute of Technology; Johannes Haushofer, Princeton University, National Bureau of Economic Research, and Busara Center for Economics; Dean Karlan, Yale University and Innovations for Poverty Action; Renos Vakis, World Bank. The authors are members of the BPSA Working Group on International Development.

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How Overcoming Demands on Attention Can Help Alleviate Poverty - Newswise (press release)

Growth in the Global Nanomedicine Market 2017-2021 trends, forecasts, analysis – satPRnews (press release)

Global Nanomedicine Market 2017-2021

This Nanomedicine market research is an intelligence report with meticulous efforts undertaken to study the right and valuable information. The data which has been looked upon is done considering both, the existing top players and the upcoming competitors. Business strategies of the key players and the new entering market industries are studied in detail. Well explained SWOT analysis, revenue share and contact information are shared in this report analysis.

Download sample pages of this report:http://tinyurl.com/y7bs9wea

Data integration and capabilities are analyzed to support the findings and study the predicted geographical segmentations. Various key variables and regression models were considered to calculate the trajectory of Nanomedicine market. Detailed analysis is explained and given importance to with best working models.

Geographically, the segmentation is done into several key regions like North America, Middle East & Africa, Asia Pacific, Europe and Latin America. The production, consumption, revenue, shares in mill UDS, growth rate of Nanomedicine market during the forecast period of 2017 to 2021 is well explained.

The ongoing market trends of Nanomedicine market and the key factors impacting the growth prospects are elucidated. With increase in the trend, the factors affecting the trend are mentioned with perfect reasons. Top manufactures, price, revenue, market share are explained to give a depth of idea on the competitive side.

Each and every segment type and their sub types are well elaborated to give a better idea about this market during the forecast period of 2017 to 2021 respectively.

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About Us:Key Market Insights is a stand-alone organization with a solid history of advancing and exchanging market research reports and logical surveys delivered by our numerous transnational accomplices, which incorporate both huge multinationals and littler, more expert concerns.

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Director of The Baby Place at Park Ridge Health earns doctorate in nursing practice – Mountain Xpress (blog)

Press release:

Park Ridge Health is celebrating the success of Beth Cassidy, DNP, MSN, RNC-OB, NE-BC, Director of The Baby Place at Park Ridge Health who recently earned her Doctorate of Nursing Practice degree.Cassidy has been the director of The Baby Place at Park Ridge Health since 2011. In her time as director, The Baby Place has earned national recognition for its exemplary care for mothers and babies across Western North Carolina, including the Womens Choice Award as one of Americas Best Hospitals for Obstetrics.Cassidy says she embarked on the journey to earn her doctorate because of her love of learning and her love for empowering her team. As a unit director in a small facility, which I prefer, you have to be an educator, said Cassidy. My team supported me through the two full years of doctorate work in anticipation of how we would turn it around to be directly applicable to each of them and their goals of expanding their skills.Park Ridge Health makes it a priority to discover the goals each of our employees may have for their lives and then encourages and empowers them to achieve those goals, said Jimm Bunch, Park Ridge Health President and CEO. Beths determination and drive to expand her skills as a caregiver and as a nursing leader are an inspiration, not only to her team, but to the entire Park Ridge Health family.The Baby Place at Park Ridge Health has become the labor and delivery center of choice for hundreds of families across Western North Carolina. Cassidy works as part of a caring team of Physicians, Nurses, Midwives, Lactation Consultants, Childbirth Educators and other support personnel to bring families the best possible care, so they can focus on one of the most important experiences of their lives. The Baby Place at Park Ridge Health cares for women through their choices which range from traditional delivery, to natural labor, to midwifery. In 2016, Cassidy and her team helped welcome nearly 650 babies into the world. To learn more about The Baby Place at Park Ridge Health, call 855.PRH.LIFE (855.774.5433) or visit myPRH.com.About Park Ridge Health: Founded in 1910, Park Ridge Health is dedicated to meeting the health care needs of our growing communities, providing high-quality, compassionate care in a Christian environment. In 1984, Park Ridge Health became a member of Adventist Health System, a family of 45 exceptional, faith-based hospitals across the country that operate independently to deliver care and services that best meet the needs of their communities. Leading the way in many medical firsts for the region, Park Ridge Health is the first hospital in Western North Carolina to offer nanomedicine in the operating room with the Nanolock Spinal technology and the only hospital in the region with the Pro-Axis Spine Surgery table. Park Ridge Health provides personalized care at more than 30 locations, offering a dedicated network of more than 250 physicians and providers, cardiac care & rehabilitation, emergency services, nationally awarded cancer care, state-of-the-art surgical care, full-service orthopedic care, an award-winning labor & delivery experience, and a full range of imaging services. For more information about Park Ridge Health or to find a physician, please visit parkridgehealthor call 855.PRH.LIFE (855.774.5433).

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Director of The Baby Place at Park Ridge Health earns doctorate in nursing practice - Mountain Xpress (blog)

Longevity Fund raises cash to back anti-aging startups | FierceBiotech – FierceBiotech

Longevity Fund has raised $22 million to make a fresh wave of investments in companies working to treat age-related diseases. The financing positions Laura Deming,who started work on the fund before turning 18, to follow up on the bets she has already placed on companies such as Unity Biotechnology.

The new fund is small in size compared to many of todays biotech investment vehicles. But the track record of Demings first, $4 million fund suggests the MIT dropout and her team will use the money to make investments in companies worth keeping tabs on.

Longevity Fund has invested in five companies to date. The portfolio includes Unity, an anti-aging startup that extended its series B round last week to bring the total up to $151 million. Longevity Fund also participated in a $25.6 million series A in Precision BioSciences, which went on to pen an immuno-oncology pact with Baxalta and committed cash to Metacrine before Novo Nordisk took up an option on its FGF1 program. 2014 Fierce 15 company Navitor is also in the portfolio.

Deming plans to use the new money to invest in eight to 10 companies, suggesting the fund will continue to place relatively small bets. That partly reflects the funds desire to act as much as a bridge to other investors as a source of capital itself. And, when it comes to drumming up interest in anti-aging startups, Deming thinks things will be easier than back when the first fund got going in 2011.

Earlier, our biggest challenge was getting other investors on board and convincing them that aging has become a place to play. Now thats a nonissue, which is great. Our job is to help the companies get other investors on board, so its wonderful to see excitement in the space begin to build, Deming told TechCrunch.

Deming was years ahead of the uptick in interest in anti-aging research. More than a decade ago, aged 11, Deming wrote to Cynthia Kenyon, Ph.D., the molecular biologist (and one of FierceBiotech's "Top women in biopharma 2015") who was one of the first people Art Levinson, Ph.D., and Hal Barron, M.D., hired to work at Googles anti-aging offshoot Calico. Deming asked to visit Kenyons lab at UCSF. A year later, Deming was working at the lab on research into how genetic and environmental changes alter lifespans.

That led Deming, via a spell at MIT, to a fellowship program set up by Peter Thiel that gave her the chance to found Longevity Fund. Six years later, Demings interest in anti-aging looks prescient and the fund is equipped to step up its activities.

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The Search for Truth, Part 2: There Are No Agnostics – Patheos

In the previous article, we discussed the sad fact that most people aren't bothering to take a step back from their societal influences to ask real questions and go on a quest for truth; that the masses blindly take upon themselves the assumptions about life and reality inherent in the society that raised them.

For example, in our time and place, there are certain in-born assumptions, and to claim anything contrary to them in a modern-day so-called "progressive" institution will result in people looking at you like you fell off of Mars and will get you branded as "uneducated" or "radical." One so-called natural and obvious given of our time is that truth is relative"You have your truth; I have my truth. And if I don't believe your truth, then your truth is not truth for me."

However, there is an obvious response to this: "So are you saying that's the truth?"

When you get down to it, the 'truth is relative' claim is making the same claim of objective reality and truth as all other claims. It is saying 'I am absolutely right about truth being relative, and anyone who believes anything contrary to what I believe is wrong'. Ironically, we find that despite the fact that such "liberal open-mindedness" is associated with free-spirited all-inclusiveness, it is the bearers of this message and belief system who seem to take charge on every social issue, thereby making the by-default claim of 'I'm right. You're wrong. And I'm going to do my best to force you to change'.

This cowardly hiding behind the guise of open neutrality while making a non-stated built-in claim and assumption of objective correctness brings to mind the all-too common response that I confront to the belief-in-God question.

Approximately 50 percent of the students I meet claim they are agnostic, unsure about whether or not there is a God. Out of that 50 percent, guess how many observe any kind of religious practice (other than the occasional prayer and charity sponsorship of a "Brovember" moustache).

That's right, 0 percent.

I have yet to meet the individual who tells me, "I am not sure whether or not there is a God who gave the Torah so I am keeping the commandments just in case." (No, in this case being a nice guy does not count as religious practice. No agnostic is nice simply because the Torah says "Love thy neighbor." They are nice because of societal norms and conditioning. Show me something this agnostic does that his society isn't also preaching.)

Hiding behind the neutrality of agnosticism works in theory, but in practice there are only two options: believer or denier. Either there is a God who gave the Torah or there is not a God who gave the Torah. Just as whether or not you are aware of gravity, the effects of smoking, or the fact that 2+2=4 does not change those realities and their effects, whether or not you are aware of any reality does not change that reality and its effects.

Any realist knows this.

In fact, if we were to gather together a believing member of every belief system on Eartha Jew, Muslim, Christian, Hindu, Buddhist, atheist, Nazi, etc.you might think there is nothing you can find that they would all agree on. However, if they are all realists, there is one thing they will all see eye-to-eye on, and that is that there is nothing more important than to figure out who (if any of them) is right. There is nothing more paramount than to clarify what is truth and correct in the world. After all, given that we are looking to get the most out of life, it is of utmost importance to uncover what is reality in order to make the most in-tune, educated, and best decisions possible regarding all aspects of life.

Similarly, when we are approached by a lost Jewish soul giving Judaism one last chance before he leaves it for good, we must begin by showing the depths of what Judaism really has to offer the individual, to explain the "whys" of Judaism, to break false stereotypes and stigmas, and to bring meaning and understanding to the seemingly hollowed "traditions" and "rituals" of Judaism.

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The Search for Truth, Part 2: There Are No Agnostics - Patheos

Taylor Swift, After A Cryptic Week, Announces New Record – NPR

Taylor Swift's new album is called Reputation, which... a bit on the nose, right? Courtesy of the artist hide caption

Taylor Swift's new album is called Reputation, which... a bit on the nose, right?

Taylor Swift has announced Reputation, her sixth album. After a cryptic, drip-drop, nearly weeklong lead-up complete with easter-eggs like putting "ivegotablankspace" in a website's source code designed to stoke theorizing by superfans, Swift confirmed via social media that the album Reputation will arrive Nov. 10, and fans should expect its first single Thursday night.

It was five days ago now that the country-superstar-turned-pop-superstar wiped clean her social media accounts, erasing many happy squad memories in the process, to begin the sniper-like (viper-like?) calibration of Reputation's unveiling. Beginning this week, three cryptic videos were posted exquisite corpse-style, gradually revealing the body of a snake. (Not for nothing, the first came in the hours leading up to the eclipse at 2:44 p.m. on Monday, almost exactly when her fellow New York residents turned their eyes skyward, leading some to speculate she was about to try and eclipse an actual eclipse. )

The graphomaniacal cover art, revealed today, reads as a not-so-subtle allusion to the controversies and mini-backlashes Swift has had since the release of 1989. For every publicity win, there have been accusations of pettiness or political agnosticism.

The timing is notable, too. Swift's album releases are normally like clockwork: every two years, in mid-autumn, since 2006. The addition of an extra year to that marketing algorithm intensified anticipation, and expectation, around the new music, especially considering Swift's exponential growth in profile around the world since shucking her country roots on her last album. Crucially, and savvily, the release date is after the cutoff for 2018 Grammy consideration, extending its lifespan into the following year like Swift albums before it.

As for that weird snake is it a little for shade Calvin Harris and Kim Kardashian? We can't keep up with all of the Insta-drama.

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Taylor Swift, After A Cryptic Week, Announces New Record - NPR

Diverse programming and experiential learning top of mind for SEHHB Interim Dean Paul Rose – RiverBender.com

EDWARDSVILLE - The Southern Illinois University Edwardsville School of Education, Health and Human Behaviors (SEHHB) diverse programming offers students powerful learning opportunities that are not readily available elsewhere, according to Interim Dean Paul Rose, PhD.

In his interim role as leader of the School, Rose is focused on working collectively with faculty and staff to orient academic programs around student needs. A key component in fostering student success, he says, is the infusion of experiential learning opportunities into the programming which covers education, health sciences and behavioral science.

Students in the School of Education, Health and Human Behavior get a diversity of experiences from our wide range of disciplines, Rose said. We continue to expand opportunities for students through new programming and innovative learning environments.

Were particularly excited about the imminent launch of a public health graduate program. This will add to our health science offerings and allow us to contribute public health leaders to the region. Additionally, our new nutrition laboratory is providing applied learning experiences for students in our growing nutrition program.

The School also prides itself on community engagement activities and outreach clinics that not only create hands-on experiences for students, but also provide tremendous value to members of the community.

Were grateful for the partners we have throughout the region and want to continue to build on those relationships, said Rose. These partnerships allow our students to become involved in the community and apply their knowledge in the field.

Also contributing to student success, is the Schools unique emphasis on student mentoring through faculty and professional advising, as well as research supervision.

Through strong mentorships, students are able to get the advice they need to be highly effective in achieving their goals, Rose explained. Were enthusiastic about educating citizens who will contribute to their communities and become highly effective employees within the diversity of disciplines that our School represents.

The SIUE School of Education, Health and Human Behavior prepares students in a wide range of fields including public health, exercise science, nutrition, instructional technology, psychology, speech-language pathology and audiology, educational administration, and teaching. Faculty members engage in leading-edge research, which enhances teaching and enriches the educational experience. The School supports the community through on-campus clinics, outreach to children and families, and a focused commitment to enhancing individual lives across the region.

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Sylvia Sims Bolton appointed new Waukegan 1st Ward alderman – Chicago Tribune

A clinical therapeutic counselor with the Gateway Foundation and anger management educator at the Lake County jail has been named Waukegan's new 1st Ward alderman.

The City Council voted unanimously this week to approve Sylvia Sims Bolton to fill the seat left vacant when Sam Cunningham, who had served as the ward's alderman for 18 years, was elected the city's next mayor in April.

"She is a long-time resident and an incredibly capable individual and, most important, she's a wonderful person," Cunningham said ahead of Monday's vote.

As a child, Bolton moved to Waukegan where she attended what was then Carman Elementary School, Webster Junior High School and Waukegan West High School, according to a biography provided by the city.

She moved back into the 1st Ward 19 years ago when she was selected as a Habitat for Humanity partner, and helped volunteers renovate the house that would become her home, she said.

"I just wanted to improve my life for myself and my children," Bolton said. "I was a single parent. I wanted to own my own home."

The move happened while she was pursuing her undergraduate work, said Bolton, who has three grown children and seven grandchildren. She recently married David Bolton.

Emily K. Coleman/News-Sun

Sylvia Sims Bolton has an associate's degree from the College of Lake County in counseling, a bachelor's degree in behavioral science from National Lewis University, a master's degree in organizational leadership from Dominican University and an honorary doctorate degree in practical counseling from Open Arms Bible College and Seminary.

According to a biography provided by Bolton, she currently works as a therapeutic clinical addiction counselor for Gateway Foundation in Lake Villa and as a chaplain and educator at the Lake County jail with Nicasa, formerly known as the Northern Illinois Council Against Substance Abuse.

She's never served in an elected position before, but has volunteered as an local elections judge in the past, she said.

Bolton, who plans on running for the seat when it's up for eleciton in April 2019, said she thinks the skills she's learned through her work, her "people person" personality and her connections to the community will help make her a good alderman.

"I'm interested in the residents and empowering them for one thing helping my community improve," she said. "I'd like to see better communication between residents and city officials. I'd to improve safety, less violence, less drug activity, less prostitution. I'd like to see the businesses collaborate together in supporting the community, and I'd definitely like to see the church community to come together and support the residents there."

Her plan is to get businesses and churches working together and playing a more visible role in the community through block parties and events designed to help residents come together, she said.

"I think if we could get everyone on the same page instead of reinventing the wheel, that would build us a stronger community," Bolton said. "We won't be so divided."

emcoleman@tribpub.com

Twitter @mekcoleman

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Sylvia Sims Bolton appointed new Waukegan 1st Ward alderman - Chicago Tribune

Science and Society on the Vineyard – Martha's Vineyard Times

Betty Burton is the coordinator of the Adult Lecture Series at the VHPL.

Marthas Vineyard is proud of how it preserves tradition: We cherish life in the slow lane. But this is 2017 and we are part of the modern world, and the latest scientific advancements affect us as much as they do anyone.To explore how science touches all of us in our everyday lives, the Vineyard Haven Public Library, funded in part by a grant from the National Science Foundation, is in the middle of an ambitious summer program on the themes of science and society, science, and everyday life. The grant, administered by a program called Rural Gateways, with the theme of Pushing the Limits, also funds similar programs in 110 other rural libraries. It allows us to participate in a nationwide reading, viewing, and discussion series. Since the beginning of time, humans have imagined and achieved ways to push the boundaries of the physical world.We want to be stronger, smarter, more aware; with great new advances in science and technology, we are finding ways in which all of us are able to push the limits every day. The Pushing the Limits program will explore these ideas in discussions that will include recommended popular books and feature film-quality videos with authors, scientists, and everyday people who thrive on exploring the natural world.Rural Gateways, Pushing the Limits, is funded not only by NSF but also was created through a collaboration of Dartmouth College, the Califa Library Group, the Association of Rural and Small Libraries, Dawson Media Group, and the Institute for Learning Innovation. The speaker series sponsored by this grant will feature programs both this summer and next winter. A science reading group is also meeting on Mondays at 3 pm every three weeks until Sept. 11.Some of the programs so far:Jonathan White presented our very first program, Tides: The Science and Spirit of the Ocean. Mr. White a lifelong mariner traveled the globe for 20 years to examine one of the most primal forces on the planet. The result is a gorgeous exploration of the science, mystery, and history of earths oceanic tides.

In July, Dr. Daniel Goleman presented Altered Traits: Science Reveals How Meditation Transforms Mind, Body, and Brain. Dr. Goleman is an author, psychologist, and science journalist. For 12 years, he wrote for the New York Times, reporting on the brain and behavioral sciences. He is probably best known for his books on emotional intelligence. He has recently written a book with the Dalai Lama, A Force for Good.

On August 10, award-winning science journalist Peter Brannen, presented his new book, The Ends of the World: Volcanic Apocalypses, Lethal Oceans, and our Quest to Understand Earths Past Mass Extinctions. As new, groundbreaking research suggests that climate change played a major role in the most extreme catastrophes in the planets history, Peter took us on a wild ride through the planets five mass extinctions and, in the process, offered us a glimpse of our increasingly dangerous future.

On August 17, Donald Berwick, MD, MPP FRCP, president emeritus and senior fellow, Institute for Healthcare Improvement, and former administrator of the Centers for Medicare and Medicaid Services, spoke about Health Care as it Should Be. A pediatrician, Dr. Berwick has served on the faculty of the Harvard Medical School and Harvard School of Public Health, and on the staff of Bostons Childrens Hospital Medical Center.

On Thursday, August 24, at 7 pm, Dr. Henry Kriegsteins subject will be Digging for Dinosaurs in the Badlands. Dr. Kriegstein will describe his passion for paleontology, organizing private digs in the Dakotas, Wyoming, and Montana, and collecting dinosaur fossils. One fossil, which Dr. Kriegstein bought from a collector in Tucson, turned out to be a completely new, previously undiscovered mini T.rex, now named Raptorex kriegsteini. Every summer, Dr. Kriegstein returns to the Badlands and continues his search for fossils. He considers it a philosophical perspective on the mystery of life and the beauty of the mineral-laced fossils.

On Wednesday, August 30, at 7 pm at the Katharine Cornell Theatre, the library will host a panel CRISPR and Genetic Editing: Uncharted Waters. Leading scientists and bioethicists from Harvard, MIT, Harvard Kennedy School, Stanford and the Woods Hole Oceanographic Institution will discuss the astounding new techniques that make editing DNA nearly as easy as editing an email (well, that is if you have a degree in molecular genetics). Along with vast potential for curing disease, feeding the world, and eliminating pollution come vexing issues of fairness, safety and morality.

Included on this panel will be Dr. Sheila Jasanoff from Harvards Kennedy School. She is one of the worlds leading bioethicists. Simply put, her job is to think and talk about the ethics of the work being done with gene editing. Professor Kevin Esvelt from the MIT Media Lab is director of the Sculpting Evolution group, which invents new ways to study and influence the evolution of ecosystems. His current project is developing mice that are immune to Lyme disease and releasing them on Nantucket. Professor Neel Aluru, of the Biological Labs at Woods Hole Oceanographic Institution, is in the field of environmental epigenetics, which involves studying how environmental factors interact with DNA, turning genes on or off. WHOI is one of the premiere institutions in the world for this kind of research. Professor Jeantine Lunshof, is an assistant professor at the Department of Genetics, University Medical Center Groningen, the Netherlands, and currently a visiting professor at Harvard. She is a philosopher and bioethicist, based in the synthetic biology laboratory of Dr. George Church. As an embedded ethicist, Dr. Lunshof works with scientists at all stages of their research to help identify potential areas of concern. MV Times science columnist, Professor Emeritus Paul Levine from Stanford, will open with introductory remarks about the short history of genetic engineering from the 70s. John Sundman will moderate the panel. His background includes writing and speaking at various institutions about CRISPR. This presentation is funded in part by a grant from National Science Foundation and Califa Library Groups.

As part of this grant, we have started a Science Book Club. So far we have read When the Killings Done by T. C. Boyle and Thunderstruck by Erik Larson. For each meeting we have viewed interviews by the authors, who discuss their take on the science in their stories. On Monday, August 28, at 3 pm we will discuss Arctic Drift by Clive Cussler. The topic of this section is Survival and how it fits into our worlds of science. On Monday, Sept. 11, at 3 pm we will discuss Land of the Painted Caves by Jean Auel and our subject will be Knowledge.

The series will continue into 2018 with more books and speakers to come.

Im happy to say that getting this grant has prompted me to re-establish our connection to the Woods Hole Marine Biological Lab and the Woods Hole Oceanographic Institution, both world-class research institutions that you can almost see with the naked eye from Vineyard Haven.

This series has special importance to me. Long before moving to the Vineyard I was a research scientist in molecular biology labs in Indiana, North Carolina, and Boston. A lot of the work I did was pure research on viral DNA, with no immediate real-world impact. But in North Carolina I was part of a research team that worked on a vaccine for Haemophilus influenza Type B. Before the vaccine, it was the leading cause of meningitis and other invasive bacterial diseases among children younger than 5. But my biggest thrill came when I was a graduate student. I was invited to present my research at Cold Spring Harbor Laboratory in 1978. That was the mecca for all DNA researchers then. I was in the middle of giving my talk when I looked up and saw Francis Crick at the back of the room, standing next to James Watson [geneticists who won the Nobel Prize for solvin
g the structure of DNA], both of them looking right at me. I nearly fainted.

For more information and schedules in one place, visit vhlibrary.org.

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Science and Society on the Vineyard - Martha's Vineyard Times

USC’s dean drug scandal could take a costly toll on the school’s legal battle with the UC system – Los Angeles Times

Six months after Dr. Carmen Puliafito stepped down as dean of USCs medical school, he was called by the university to give sworn testimony as a witness in a lawsuit the institution was facing.

It was a sensitive matter with hundreds of millions of dollars potentially at stake, and two attorneys for the university sat with him as he answered questions.

Almost immediately, the opposing lawyer hit on a topic that was a closely guarded secret at USC: The circumstances of Puliafitos abrupt resignation in March 2016.

The former dean had a ready explanation, saying he had taken advantage of a unique opportunity at a biotech company. The response was succinct, matter-of-fact and, in light of recent revelations about his drug use and troubled tenure at USC, far from the whole story.

Paul Pringle, Harriet Ryan, Adam Elmahrek, Matt Hamilton and Sarah Parvini

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Of the many consequences of the Puliafito scandal for USC, few are as high-stakes as the possible effect on the court case that prompted his testimony last year.

Puliafito was expected to play a role in defending USC in the legal battle with the University of California over the defection of a star UC Alzheimer's disease researcher.

Puliafito helped woo the scientist and dozens of other prominent academics as part of a strategy by USC President C.L. Max Nikias to vault the university into the ranks of elite research institutions.

UC is seeking $185 million in damages along with a punitive award that could be several times that amount.

With all thats out there about him, hes going to have a serious problem coming off as credible and being believed, said Los Angeles attorney Brian Panish, a civil litigator who has represented clients in suits against both schools.

A Times investigation published last month revealed that Puliafito partied and used drugs with a circle of criminals and addicts while serving as dean. Puliafito engaged in this behavior during the period in 2015 in which he was recruiting the researcher, according to interviews with his associates and text messages they exchanged with him.

A UC spokeswoman said the school would not discuss its legal strategy other than to say we are vigorously pursuing this case against USC.

An attorney for USC said no decision had been made on whether to call Puliafito as a witness, but insisted the former deans testimony was not important to the universitys defense.

Hes a bit player in this, said attorney John Quinn.

In court filings earlier this year, lawyers for USC highlighted a portion of the deans testimony in arguing that the case should be dismissed.

Puliafito testified that the university wanted UC San Diego researcher Paul Aisen to join the faculty whether or not he brought along hundreds of millions of dollars in grant funding, a rejection of UCs claim that USC was motivated by money in recruiting the scientist.

Legal experts said that even if USC decides not to use Puliafitos testimony, UCs legal team could ask for copies of his personnel record and attempt to make an issue in court of his conduct. That would set up a fight between USC and UC over whether jurors should be told about the skeletons in Puliafitos closet if the case went to trial.

The trial judge would have to decide whether the prejudicial, inflammatory value is outweighed by the probative value, said Manhattan Beach civil lawyer John Taylor, who has represented clients with legal claims against USC.

The judge, Taylor added, might say, Suppose he was out partying like a rock star? How does that make it more or less believable to a jury?

USC is anticipating that UC will try to make Puliafitos drug use a line of attack.

I believe that they would do anything they could to try to poison the well, including introducing the deans personal problems, USC lawyer Quinn said, adding that he expected a judge to reject such attempts as irrelevant.

The case is on hold while USC appeals a U.S. district judges ruling that moved the suit from federal court to San Diego County Superior Court, where it was originally filed. No trial date has been set.

By the time Puliafito was scheduled to be questioned under oath, the case was in its second year and UC had brushed off entreaties by USC to settle the matter out of court. USC deputy general counsel Stacy Bratcher and other university lawyers met with the former dean three times to prepare him for the deposition, he later testified.

On the day of his testimony, Bratcher and another lawyer sat with him at a downtown law firm as he was questioned for about six hours, according to a transcript of the testimony. Portions of the transcript were redacted at the request of USC.

Puliafito said he had been deposed 20 times in his life, including in court cases where he was a medical expert. On a video recording of part of the deposition, he appears self-assured, offering short, precise responses and brushing aside many questions as hypothetical and difficult to answer.

A few minutes into his testimony, he was asked for the circumstances of your ceasing to be dean of the medical school. An attorney for USCs outside law firm, Viola Trebicka, initially protested that the question was overbroad and vague objections a judge would rule on a later date and then directed him to go ahead and answer.

I had a unique opportunity in the ophthalmic biotechnology industry, and I was able to continue my employment at USC on sabbatical and work for this biotech company, he said.

The full story was more complicated. USC acknowledged after The Times report that the dean quit his post during a confrontation with the university provost about his behavior and job performance. That showdown capped years of complaints from faculty and staff about Puliafitos drinking, temper and public humiliation of colleagues, according to interviews with former co-workers and written complaints to the administration.

He was not offered the biotech job at Ophthotech, a firm run by two longtime friends, until more than a month after he resigned, according to a company spokesman.

Quinn said he did not know whether lawyers for USC and Puliafito discussed how he would answer questions about his resignation before the deposition. He said that attorneys for his firm would never sponsor false testimony. We would never knowingly permit a witness to lie. In a statement, a USC spokesman said the university general counsels office, where Bratcher works, would never encourage a witness to perjure himself.

Experts said UC could ask a judge to reopen the deposition in light of the new information about Puliafitos past conduct.

I would get the personnel file and also question him about what happened. Maybe there is more that is not out there yet, Panish said.

The court fight is being closely watched in academic circles. UC took the highly unusual step of suing its academic rival in 2015 after years of frustration over USCs recruitment of faculty members who were the recipients of big research grants. These grants are an important income source for the state system.

These transformative faculty, as they are known at USC, have been key to President Nikias strategy for raising the universitys national reputation. Puliafito spearheaded the effort during his eight-year tenure as dean, recruiting more than 70 academics from the UC schools, Stanford, Harvard and other prestigious rivals.

After Puliafito helped woo away two well-funded UCLA neurology researchers in 2013, UC administrators were outraged, and complained to government regulators, according to court filings. It was not unusual for professors to move to other institutions, often with the first university cooperating in the transfer of grant funding to the new school. But in UCs view, USC had acted beyond accepted norms by targeting academics based on grant funding and strategizing secretly with those researchers while they were still employed by UC about moving grants to USC. The schools reached a confidential settlement requiring USC to pay UCLA more than $2 million, according to a copy of the agreement obtained through a public records request.

Late the next year, the dean set his sights on another UC prize: Alzheimers expert Paul Aisen. The UC San Diego neurology professor was a global leader in the search for a cure for the disease, and federal agencies and drug companies were expected to send more than $340 million in research grants to the lab he ran over the next five years

Nelvin C. Cepeda

Alzheimer's researcher Dr. Paul Aisen.

Alzheimer's researcher Dr. Paul Aisen. (Nelvin C. Cepeda)

I am going to get more involved in this personally and quarterback the process, he wrote in an email to Provost Michael Quick in April 2015. We need this to happen.

USC offered Aisen annual compensation of $500,000 a salary bump of $110,000 along with a home loan and other perks. He moved to USC in June 2015.

The loss reverberated at the highest levels of the UC system. President Janet Napolitano unsuccessfully lobbied the head of drug company Eli Lilly, a major funder of Aisens work, to keep its grant money at UC.

In July 2015, UC sued USC, Aisen and his lab colleagues for breach of fiduciary duty, interference with contracts, computer crimes and other claims. The university said USC had conspired with the researcher while he was still working for UCSD to interfere with the public universitys contractual relationships with grant funders and to seize control of critical clinical trial data.

Subsequent filings suggested the depths of the hard feelings. In one, UC complained that the departing scientists had even made off with paper clips paid for by UCSD. In another, their lawyers described USC as a predatory private university with a law-of-the-jungle mind-set.

Astrid Riecken / Getty Images

University of California President Janet Napolitano

University of California President Janet Napolitano (Astrid Riecken / Getty Images)

USC and Aisen countersued for defamation and other charges. Their lawyers wrote in the complaint that they were ready to settle the litigation and suggested the blame rested with UC for failing to fund Aisens work adequately. When he found a school that would, they wrote, UC engaged in petty academic politics, including trying to make him sign a loyalty oath and cutting off his email and phone service, tactics that they claimed endangered patient safety.

Aisen, Puliafito and other USC administrators insisted in depositions that the university had done nothing wrong. In his sworn testimony, the former dean testified that he was prepared to offer Aisen a faculty position even if his lucrative research grants stayed behind at UCSD.

You were indifferent to whether or not the grant funding transferred with Dr. Aisen, the UC lawyer asked.

Yes, Puliafito said, adding: Thats the risk we were willing to take.

San Francisco lawyer Stephen Hirschfeld, who has defended UC and other universities in civil suits, said the involvement of other officials in Aisens recruitment could blunt the impact of Puliafitos credibility issues.

The university provost, a faculty chair, medical school administrators, and human resources officers played key roles in luring Aisen, according to court filings and deposition testimony.

You could have a situation where the dean says one thing and several other administrators confirm that it is true, Hirschfeld said. Focusing too much on Puliafito, he said, might make UC look cruel or desperate to the jury.

Youve got to think really hard if its worth it to attack this guy in this way, he said.

Taylor, the Manhattan Beach lawyer, said that jurors could see Puliafito as a reflection of the values of the university and the decision makers there.

If terrible evidence comes in about him, it is terrible evidence for the school, he said.

The deposition offers tantalizing clues about the relationship between Puliafito and USC. At one point, the former dean was asked when he had last looked at the USC ethics code.

Six months ago, he replied. The deposition was on Sept. 23, 2016 just a day short of the six-month anniversary of the meeting at which the provost confronted him with complaints from colleagues about his behavior.

harriet.ryan@latimes.com

Twitter: @latimesharriet

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USC's dean drug scandal could take a costly toll on the school's legal battle with the UC system - Los Angeles Times

‘Grey’s Anatomy’ Season 14 Will Be ‘Funnier,’ ‘Lighter’ – Moviefone

"Grey's Anatomy" has been breaking our hearts and causing us to go through a million tissues for 13 seasons, but Season 14 has a new prescription: fun.

Actor Giacomo Gianniotti, who plays Andrew DeLuca, says the new season is "funnier, it's sexier, it's lighter."

"We're going to have fun this season," he told TV Line.

As he explained, the sho has "been dreary for a long time." Yeah, between McDreamy's death and Lexie's death and Mark Sloan's death it's a wonder that anyone is still alive in Seattle.

"There's just been a lot of separation and loss, so we want to show the characters having some fun," Gianniotti said. "Also, a lot of the men are single now, so we're going to explore what that dynamic is like."

Ooh, there hasn't been a good bromance since Derek and Mark!

"Grey's Anatomy" Season 14 premieres Sept. 28 at 8 p.m. on ABC.

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'Grey's Anatomy' Season 14 Will Be 'Funnier,' 'Lighter' - Moviefone

Eric Dane Only Watched Three Episodes Of ‘Grey’s Anatomy’ – HuffPost

Eric Dane spent six seasons playing Dr. Mark Sloan onGreys Anatomy, but the actor says he barely watched any episodes of the hit ABC series. Ever.

In a recent interview with HuffPost at Build Series, Dane revealed, I watched three episodes of the show while I was on it. After all, he said, I was there when it happened, so I didnt need to see it.

So, its safe to say he doesnt keep up with the series now. But he does keep in touch with some of his former cast members, including Ellen Pompeo and Justin Chambers. Hes also still friendly with series creator Shonda Rhimes.

Shondas great, he said.Im still friends with her to this day. One thing that you do with Shonda is that you dont deviate. Thats one of the biggest lessons you learn is that you stick to the script.

Even though hes been off the series for five years now, Dane still gets called by his Greys nickname, McSteamy. But he doesnt seem to mind too much.

Ive been called a lot worse, he joked. It never did anything bad for me that nickname. So, I dont mind it ... Its not what Im doing now, so it does get a little tiring. But its not something that really upsets me.

Shortly after leaving Greys Anatomy Dane jumped into another big role. He currently stars as Tom Chandler in TNTs The Last Ship, which returns for Season 4 on Sunday. The series follows what happens after a global catastrophe wipes out the bulk of the population. Danes character a Navy captain faced a series of changes at the end of the last season. Season 4 will pick up where that storyline left off.

Tom Chandler left the Navy after doing something that he felt was morally way against everything he stood for. And hes in a self-imposed exile, Dane said.

Chandler is now in Greece living the life of a fisherman, and Dane says its only a matter of time before he finds some trouble, as he tends to do.

Tom Chandler has to find his way back into the Navy, into the fray, Dane said.

Dane says he really enjoys playing the character and can relate to some of the conflict Chandler experiences on the show. But unlike Greys Anatomy,starring in The Last Ship is physically challenging.

Its a lot of hard work. I enjoy it. But at the end of the day, youre home and you actually feel like you worked.

So, we have one last question: Does Dane watch episodes of The Last Ship?

Sometimes theyll be stupid enough to take my notes when I watch an episode, he said about the shows producers. I always try to offer like, I think theres a better take in there somewhere.

But he admits, its definitely uncomfortable seeing himself on TV, even after all these years.

Im not a big watcher of myself, he said. You start looking at things you shouldnt be looking at that have nothing to do with anything of importance.

The Last Ship returns with a two-hour season premiere this Sunday at 9 p.m. ET on TNT. Check out our full Build interview with Dane below.

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Eric Dane Only Watched Three Episodes Of 'Grey's Anatomy' - HuffPost

Anatomy of an epidemic – Times of India (blog)

It is just right, that the Health Ministry has chosen the IMA (Indian Medical Association), Indias largest voluntary autonomous body of doctors from all fields. The key features that make it suitable for the Gorakhpur enquiry, is that this body would be looking into the matter medically, and not with an eye of punishment. I am quite sure, with a vast, mostly non-government aided practicing experience, many must already be knowing what in all probability would mainly be a viral epidemic. Surely there would be areas of suggestions for improvement of overall care and preparedness.

Another advantage, it is not answerable and should not lean to any political entity, nor can itbesqueezed around by protocol, as it is not a Constitutional body, unlike the MCI. That it shall use true scientific principles, is understood.

If you look from the point of advantages of adversity, it is just as well that awareness has finally spread, systems are upgraded, and if this turns out to be a viral epidemic, the best standards of epidemic control, and prevention shall have to be put in place.Gorakhpur is a city that has had many trysts with epidemics.

To put it lightly, sometime back I happened to open the topic with a gentleman from the place. A citys description is best stated in its own language. This is what that gentleman said, Aap bas yoon samajhiye ki Baman (brahmin), Bimaari (disease), aur Bihari (no offence, every community has a sore point) sey Gorakhpur trust (infested, soft T) hai! Never had a better summary, which the IMA team may keep in mind!

The first reported viral epidemic in Gorakhpur was in 1978 (Japanese, JE), where 1022 cases were reported, with 297 deaths. After that the road has been rather bumpy.

The year 2005 was rather tragic. The outbreak reported was 5,737, mostly JE. 1344 children died.

But to get the full view, the Directorate of National Vector Borne Disease Control Program (NVBDCP), has reported 26,668 between 2010-2017. The break up was 24,668 of Acute encephalitis syndromes (AES), an all-encompassing terminology WHO, though it settles down to a condition of fulminant encephalitis, as against the known virus JE. There were 4,093 deaths in the same period for AES, and 307 in the JE cases.

Gorakhpur has the dubious reputation of being the world capital of JE, though the total worldwide population at exposure, and that which may suffer is close to 3 billion, which would include South-East Asia prominently.

This years epidemic was unfortunate, but such is the story of all vagaries of nature. The BRD Medical College, may have expanded a bit, but that it should be epidemic ready, is difficult to imagine. For that matter, which medical facility shall have 2,000 extra ICU beds ready where the disease does not accept anything as a cure, and supportive care is all that can be given.

One may overstock antibiotics, saline drips, ventilators, even rooftops with oxygen, but the real process that takes down the patient is the inflammation inside the brain that causes increase in the respiratory rate-a central process, but not a lung pathology that would be amenable to oxygen.

However, medicine has a place for palliation and one can understand the emotions of those who felt that oxygen was in shortage. Ventilators, oxygen are what can be done as a palliation, and as a physician I would go a step further in what soothes the patients relatives. But the fact is that the gasping stage many patients reach due to disrupted central ventilatory centre, is not because of loss of oxygen, and even ventilatory support is less likely to change course.

However, I cannot say that such prop-ups facilities should not be ready. The outcome of the disease may not change though. I suppose this is a key question the IMA enquiry committee may like to take. Till we have vaccines that ensure protection, and till we have medicines that are curative, some actions can be initiated to change or dampen the incidence of the disease.

It is widely stated that Gorakhpur, a densely populated town, close to the Himalayan foothills of Nepal, has many water-bodies, and water pooling after the rains start, which is the period between May and November. Being a vector-borne disease, regular fogging in such areas should start to keep the population of vectors down.

Generic sprays and mosquito repellent ointments should be for free distribution (much like free condoms as disease prevention).

Health workers may be doubled to keep appropriate control over the still waters. Mosquito sprays and creams should be checked and supplied at every house. Expenses need not be high, and would also create extra rural jobs.

Surely, the enquiry shall bring better facilities to the BRD Medical College that may reduce fatalities in other diseases. Should doctors be suspended or dismissed? There may be specific cases, but I fail to understand any direct action or omission that would throw the blame directly on them.

Transferring doctors? That would be the best gift!

The inspection by IMA pending, the remedial aspects are technical, mostly regarding the methods of mitigating the vector population, and giving a first shield to the population.

A few years ago, Rotary International and IMA, made India Polio-free.

Innovative epidemiologic techniques need to be put in place. May I add to the vocabulary, Technical mosquito nets You got me wrong The ones that keep the mosquitoes trapped in, the way they do in Punjab!

To make the tragedy bearable, may I be spared this one:

Badaltey zamaaney, mein khayaal kuchh aisa aaya, Parwaana bhesh badalkar, kahin Qaatil bankey to na aaya(In a changing world, a thought just came to mind,Was a killer vector, impersonating the romantic drone?)

PS: One of the theories regarding King Tut is that he suffered malaria shortly before he occupied his Grand tom.

DISCLAIMER : Views expressed above are the author's own.

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Anatomy of an epidemic - Times of India (blog)

UNITY Biotechnology Announces Series B Financing Extension … – Drug Discovery & Development

UNITY Biotechnology, a privately held biotechnology company creating therapeutics that prevent, halt, or reverse numerous diseases of aging, announced the closing of an additional$35 millionin Series B financing. This second close of the Series B, in addition to the initial close infall of 2016, brings the total amount of this financing to$151 million.

The UNITY Series B financing ranks among the largest private financings in biotech history. New Series B investors include INVUS Opportunities, Three Lakes Partners, Cycad Group, COM Investments, and Pivotal Alpha Limited.These new investors join the Series B led by longtime life science investors ARCH Venture Partners, Baillie Gifford, Fidelity Management and Research Company, Partner Fund Management, and Venrock. Other investors include Bezos Expeditions, Vulcan Capital, Founders Fund, WuXi PharmaTech, and Mayo Clinic Ventures. Proceeds from this financing will be used to expand ongoing research programs in cellular senescence and advance the first preclinical programs into human trials.

UNITYalsoannounced thatGraham Cooperhas joined UNITY's board of directors. Mr. Cooper was previously the chief financial officer ofReceptos,which was acquired by Celgene in 2015 for$7.8 billion.

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UNITY Biotechnology Announces Series B Financing Extension ... - Drug Discovery & Development