15-05-2012 15:25 ISH Spring Lecture Series 5/10/2012 “Genomic Medicine: Ethical, Legal & Social Implications” Technological advances have made it possible for individuals to receive vast amounts of information about their genetic susceptibility to disease. How best to integrate genomics into routine clinical care is a critical policy issue Continue reading
Category Archives: Genetic Medicine
New genetic 'map' drawn up that will give better diagnosis for breast cancer patients and more effective treatment
By Richard Hartley-parkinson PUBLISHED: 12:11 EST, 16 May 2012 | UPDATED: 06:42 EST, 17 May 2012 A genetic ‘map’ that could help give more accurate diagnoses of breast cancer has been drawn up, showing the varied landscape of the disease in more detail than ever before. Continue reading
Breast cancer study reveals 'substantial genetic diversity'
A new study of the protein-coding genes in 100 breast cancer tumors revealed vast differences among the cancers and highlights how complicated the disease really is, researchers said Wednesday. A sobering perspective on the complexity and diversity of the disease is emerging, they wrote in the online edition of the journal Nature (subscription required), which is publishing a series of studies of the genetic changes in breast cancer. Continue reading
Abraham’s genetic threads | Gene Expression
Every few days my Google Alerts have been dropping in my inbox reviews of Harry Osters Legacy: A Genetic History of the Jewish People. The latest is in the The Tablet, A Case for Genetic Jewishness: For a Jewish genetics researcher, being told inprintthat Hitler would certainly have been very pleased by your work cant be pleasant. But thats what happened in 2010 toHarry Ostrer, a geneticist at the Albert Einstein College of Medicine, when he and his colleagues published astudyshowing that Jews in three different geographical areas had certain collections of genes that made them more biologically similar to one another than they were to non-Jews in the same regions. Continue reading
Genetic test can accurately predict spread of eye cancer
Researchers at Washington University School of Medicine in St. Louis have developed a genetic test that can accurately predict whether the most common form of eye cancer will spread to other parts of the body, particularly the liver. In 459 patients with ocular melanoma at 12 centers in the United States and Canada, the researchers found the test could successfully classify tumors more than 97 percent of the time. Continue reading
Lung cancer molecular subtypes correlate with genetic alterations, patient's response to therapy
Published on May 14, 2012 at 12:51 AM Cancer therapies targeting specific molecular subtypes of the disease allow physicians to tailor treatment to a patient’s individual molecular profile. But scientists are finding that in many types of cancer the molecular subtypes are more varied than previously thought and contain further genetic alterations that can affect a patient’s response to therapy. Continue reading
Schizophrenia’s core genetic features proposed
Researchers may be closing in on diseases inherited component Web edition : 1:40 pm Schizophrenias elusive genetic roots may finally be within grasp. A new, wide-ranging effort has uncovered a set of DNA signatures that are shared by people with the disease consistently enough that the set can be used to reliably predict whether someone has the disease. If replicated, the results may point out ways to diagnose schizophrenia and suggest new targets for treatment. Continue reading
In Sperm Banks, a Matrix of Untested Genetic Diseases
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Genetic test identifies eye cancer tumors likely to spread
Public release date: 14-May-2012 [ | E-mail | Share ] Contact: Jim Dryden jdryden@wustl.edu 314-286-0110 Washington University School of Medicine Researchers at Washington University School of Medicine in St. Continue reading
In Sperm Banks, a Roll of the Genetic Dice
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Given number of inheritors, donor sperm carries risk of genetic harm
In households across the country, children conceived with donated sperm are struggling with serious genetic conditions inherited from men they have never met: heart defects, spinal muscular atrophy, neurofibromatosis type 1 and fragile-X syndrome the most common form of mental retardation in boys and others. Continue reading
Focus Groups Share Thoughts on Direct-To-Consumer Genetic Tests
May 11, 2012 Connie K. Ho for RedOrbit.com Researchers at Loyola University Chicagos Stritch School of Medicine have found that patients see both benefits and risks from direct-to-consumer genetic tests. Dr Continue reading
Genetic ‘Signature’ Predicts Breast Cancer Chemotherapy Response: Study
Scientists have uncovered genetic signs that could help doctors predict how breast cancer patients will respond to chemotherapy. Researchers led by McMaster University biochemist John A. Hassell found two sets of genes that could indicate the presence of higher levels of two proteins targeted by commonly used chemotherapy drugs. Continue reading
Molecular subtypes and genetic alterations may determine response to lung cancer therapy
Public release date: 11-May-2012 [ | E-mail | Share ] Contact: Dianne G. Shaw dgs@med.unc.edu 919-966-7834 University of North Carolina School of Medicine Cancer therapies targeting specific molecular subtypes of the disease allow physicians to tailor treatment to a patient’s individual molecular profile. But scientists are finding that in many types of cancer the molecular subtypes are more varied than previously thought and contain further genetic alterations that can affect a patient’s response to therapy. Continue reading
Advanced genetic screening method may speed vaccine development
Public release date: 9-May-2012 [ | E-mail | Share ] Contact: Joseph Caspermeyer Joseph.Caspermeyer@asu.edu Arizona State University Infectious diseasesboth old and newcontinue to exact a devastating toll, causing some 13 million fatalities per year around the world. Vaccines remain the best line of defense against deadly pathogens and now Kathryn Sykes and Stephen Johnston, researchers at Arizona State University’s Biodesign Institute, along with co-author Michael McGuire from the University of Texas Southwestern Medical Center are using clever functional screening methods to attempt to speed new vaccines into production that are both safer and more potent. Continue reading
New Genetic Discoveries and Treatment for Hepatitis C [Viewpoint]
Michael Pacanowski, PharmD, MPH; Shashi Amur, PhD; Issam Zineh, PharmD, MPH Author Affiliations: Genomics Group, Office of Clinical Pharmacology, Office of Translational Sciences, Center for Drug Evaluation and Research, US Food and Drug Administration, Silver Spring, Maryland. Treatment of chronic hepatitis C (CHC) is a prototype for personalized medicine Continue reading
New University of Florida research center to focus on rare genetic illness
With the support of a Major League Baseball star, a new University of Florida research center on an island settled by the Vikings could lead to breakthroughs about a rare genetic disorder and potentially change the course of care for high blood pressure and other common conditions. UF College of Medicine researchers studying a genetic condition called glycogen storage disease type III, which prevents children and adults from properly processing sugar stored in the body, have received support from the Johnny Damon Foundation to establish a new research center on the Faroe Islands, located in the North Atlantic Ocean between Norway and Iceland. Because of the isolation of the island chain, genetic diseases are common there, making it a fertile ground for researchers Continue reading
Innovators in Pediatric Cancer to Share Progress on Ground-Breaking Personalized Medicine Clinical Trial
Dell: WHAT The team of parents, genetic and translational medicine scientists and pediatric oncologists trailblazing personalized medicine in the treatment of deadly pediatric cancers is convening in Austin to discuss the status of the worlds first personalized medicine clinical trial for pediatric cancer and plan next steps at the NMTRC Symposium 2012. Neuroblastoma affects 1 in 100,000 children and is responsible for 1 in 7 pediatric cancer deaths. Continue reading
Checking for specific genetic variants can help identify women at high risk of PND
Researchers at Warwick Medical School have discovered a way of identifying which women are most at risk of postnatal depression (PND) by checking for specific genetic variants. The findings could lead to the development of a simple, accurate blood test which checks for the likelihood of developing the condition Continue reading
Sequenom Announces Coverage Agreement With Coventry Health Care For Sequenom Center For Molecular Medicine's …
SAN DIEGO, May 9, 2012 /PRNewswire/ — Sequenom, Inc. (SQNM), a life sciences company providing innovative genetic analysis solutions, today announced that it has signed an agreement with U.S. health insurance provider Coventry Health Care National Network to provide coverage for the Sequenom Center for Molecular Medicine’s (Sequenom CMM) MaterniT21 PLUS laboratory-developed test (LDT). Continue reading