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Monthly Archives: January 2021
Now is not the right time to split NSA and CYBERCOM – C4ISRNet
Posted: January 1, 2021 at 9:38 am
In addition to the big Russian hack, some other surprising news occurred in the cybersecurity world this holiday season. The Pentagon is reportedly considering ending the dual-hat arrangement that allows the commander of U.S. Cyber Command to simultaneously serve as director of the National Security Agency.
This idea, which has surfaced repeatedly since the standup of CYBERCOM, will not advance U.S. national security. The current arrangement has served both organizations well for years. There is no immediate need to split the two offices right now.
According to reports, the plan to end the dual-hat arrangement has been sent to Chairman of the Joint Chiefs General Mark Milley, who, according to public law, would have to sign off on the split along with acting Secretary of Defense Chris Miller.
This initiative has caused some consternation in Congress, since lawmakers enacted legislation to address this very issue. The fiscal 2017 and 2018 National Defense Authorization Acts put certain roadblocks in place to ensure a proposal to make the split would not harm national security. In essence, both the secretary of defense and chairman of the Joint Chiefs need to sign off and certify the plan will not harm national security before the arrangement is ended.
The dual-hat arrangement started in 2009 when Cyber Command was created in order to provide it with the support and resources it needed to conduct its mission. The arrangement gave the growing Cyber Command the ability to borrow manpower and other resources from the NSA.
A lot has changed since 2009. Cyber Command has built 133 Cyber Mission Force teams and has conducted sophisticated operations, such as the cyber campaign against the Islamic State, which disrupted the latters ability to distribute propaganda online. This means CYBERCOM has gained in experience and developed capacity.
But how ready is it to split its command, and can that be done without affecting its operations? More fundamentally, should splitting the command be a long-term goal?
The initial push to end the dual-hat started during the Obama presidency and was politically motivated in the wake of the Snowden controversy. But military necessity should guide this shift, not politics. So what are the arguments for and against?
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Advocates for ending the dual-hat argue that one commander can lead to unfair prioritization of one organization NSA or CYBERCOM over the other. They also question the ability for one person to effectively manage two large organizations and claim that increased use of the NSAs advanced tools could lead to their premature exposure, possibly through a CYBERCOM operation.
Advocates for keeping the current arrangement focus on the close cooperation and synergy it allows between the two organizations that help their operations, the faster decision-making process it enables and the more efficient use of resources, since the two organizations can more easily share.
While there are arguments on both sides and many see the split happening at some point down the road, two things seem clear. A split should not be done hastily or prematurely. The close cooperation between the two organizations must be preserved.
And lets not forget the timing. Right now, the U.S. government is reeling from a massive breach by suspected Russian hackers with sweeping consequences, making this an inopportune moment for large organizational changes that could hinder cyber operations.
Both the former commander, Adm. Michael Rogers, and current commander, Gen. Paul Nakasone, have expressed caution about ending the arrangement prematurely. Both have said the arrangement works and enables the close relationship between the two organizations.
The two organizations operate under different legal authorities. Cyber Command draws its authorities from Title 10, which governs military forces, and NSA usually operates under Title 50 governing intelligence functions. This mirrors how cyber operations work as well, with the need for close collaboration between intelligence and military operations.
This means that Cyber Command and the NSA are able to collaborate in a way that other military forces are not able to cooperate with their intelligence counterparts. They currently enjoy a large degree of corporate synergy, where their close cooperation and unified command makes them more effective than if they were apart.
As Gen. Nakasone has said, The National Security Agency is our most important partner; the strength of this relationship will remain critical to the defense of the nation. The agencys world-class expertise, technical capabilities and accesses are crucial to USCYBERCOMs success.
Ending the dual-hat should only be done if it will enhance the effectiveness of both organizations in their operations, and a clear plan should be created with support from Congress, as it will need congressional support to be successful. Policymakers should continue to support the growth and development of Cyber Command to ensure that it would be ready for a future split down the road.
James Di Pane is a researcher at the Heritage Foundations Center for National Defense who focuses on military cybersecurity issues.
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Edward Snowden and wife share photos of newborn son amid push for Trump to pardon NSA leaker – Washington Times
Posted: at 9:38 am
Edward J. Snowden and his wife, Lindsay Mills, announced the birth of their first child Friday amid a push for President Trump to pardon the fugitive leaker of crimes keeping him from returning to the U.S.
The couple, who have resided in Russia for the last several years, shared photos on social media showing them holding their newborn child.
Happy Holidays from our newly expanded family, Ms. Mills said on Instagram where she posted the photos. The greatest gift is the love we share, Mr. Snowden added on Twitter where he shared one of them.
Mr. Snowden, a former CIA employee and National Security Agency contractor, admittedly leaked a trove of classified documents to the media in 2013 exposing the NSAs vast operations and capabilities.
The Department of Justice under former President Barack Obama accordingly charged Mr. Snowden with stealing and violating the U.S. Espionage Act, putting him at risk of serving up to 30 years in prison.
However, Mr. Snowden has successfully avoided the long arm of the law during the last 7.5 years as a result of residing in Russia, which does not have an extradition agreement with the U.S. government.
Mr. Snowden said while his wife was expecting that they were both applying for dual citizenship to avoid the possibility of being legally separated from their son, a Russian citizen by birth.
After years of separation from our parents, my wife and I have no desire to be separated from our son. Thats why, in this era of pandemics and closed borders, were applying for dual US-Russian citizenship, Mr. Snowden said last month on Twitter.
Anatoly Kucherena, a lawyer for Mr. Snowden, said on Saturday that both Ms. Mills and her newborn son are in excellent health, Russias Interfax news agency reported over the weekend.
Mr. Snowden, 37, has previously said he will return to the U.S. if given a trial he deems fair, although some of his defenders are now pushing the president to have the case against him dropped entirely.
Sen. Rand Paul of Kentucky and Rep. Matt Gaetz of Florida, both Republicans closely allied with Mr. Trump, each advocated recently for Mr. Trump to pardon Mr. Snowden before his presidency ends.
Mr. Trump, who called Mr. Snowden a traitor prior to becoming president, said in August that he was considering granting him a pardon. He has since pardoned dozens of others.
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India, Pakistan exchange list of nuclear installations – Outlook India
Posted: at 9:38 am
By Sajjad Hussain
Islamabad, Jan 1 (PTI) Pakistan and India on Friday conducted the annual practice of exchanging the list of their nuclear installations under a bilateral arrangement that prohibits them from attacking each other''s atomic facilities.
The exchange was made in accordance with Article-II of the Agreement on Prohibition of Attacks against Nuclear Installations and Facilities between Pakistan and India, signed on December 31, 1988, the Foreign Office (FO) said in a statement here.
It said that the list of nuclear installations and facilities in Pakistan was officially handed over to a representative of the Indian High Commission at the Ministry of Foreign Affairs today, at 1100 hrs (PST).
"The Indian Ministry of External Affairs in New Delhi handed over the list of Indian Nuclear installations and facilities to a representative of the Pakistan High Commission at 1130 hrs (IST)," it added.
The agreement contains the provision that both countries inform each other of their nuclear installations and facilities on January 1 every year.
This has been done consecutively since January 1, 1992, according to the FO.
The exchange of information comes despite the ongoing tensions between India and Pakistan.
The relationship dipped after India''s war planes pounded a terrorist training camp deep inside Pakistan on February 26, 2019 in response to the Pulwama terror attack carried out by Pakistan-based Jaish-e-Mohammed terror group in which 40 CRPF jawans were killed.
Tensions between the two nations spiked further after New Delhi abrogated provisions of Article 370 of the Constitution to withdraw Jammu and Kashmir''s special status and bifurcated it into two Union Territories.
Pakistan downgraded its diplomatic relations with India and expelled the Indian high commissioner following the revocation of Article 370 in Jammu and Kashmir on August 5, 2019.
Asserting that the abrogation of Article 370 was its "internal matter", India has defended the imposition of restrictions in the Kashmir Valley on the grounds that they were put to prevent Pakistan from creating more mischief through proxies and terrorists. PTI SH NSA AKJ NSA
Disclaimer :- This story has not been edited by Outlook staff and is auto-generated from news agency feeds. Source: PTI
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Satoshi Nakamoto from NSA, AntiChrist and Other Bitcoin Conspiracy Theories – Cryptonews
Posted: at 9:38 am
Source: Adobe/afxhome
The most popular cryptocurrency, Bitcoin (BTC), is filled with conspiracy theories, ranging from the plausible to the downright absurd.
Lets take a quick look at the most common Bitcoin conspiracy theories for a good laugh or - if you choose to believe them - a peek down the rabbit hole.
On Wednesday, June 20, 2018, a new block was mined on the Bitcoin blockchain. It was a typical block, except that its hash was 00000000000000000021e800c1e8df51b22c1588e5a624bea17e9faa34b2dc4a.
It caused a massive uproar among the community, with Twitter and Reddit awash with speculations concerning the origins and meaning of the number.
The reason for the excitement around this particular block hash, something many within the community are already familiar with, is a number. First, upon a cursory glance, the number of zeros at the beginning of the block hash was similar to the ones in the block hash of the Genesis Block, or the first block of Bitcoin ever mined.
Given the lengths supposedly undertaken by the pseudonymous creator of BTC, Satoshi Nakamoto, to achieve that hash in the Genesis Block, some believe it to be meaningful. Additionally, it was pointed out that it is highly improbable for the June 2018 hash to be generated at random.
Secondly, the number that came after the first zeros was 21e8. This number is an important one in physics because it refers to the E8 Theory, which is an attempt to describe all known fundamental interactions in physics and to stand as a possible theory of everything.
Possible explanations for the event ranged from a simple chance to AI or Nakamotos resurgence and even time travel.
Possibly, the biggest mystery (together with when moon?) in the Bitcoin world is its creator Satoshi Nakamoto. It is assumed this was either a person or a group of people working in concert to create the worlds first decentralized digital currency. The people listed as possible Nakamoto candidates reads like the whos who of the cypherpunk movement, such as Hal Finney, Adam Back, and Nick Szabo, computer scientist, legal scholar, and cryptographer known for his research in cryptocurrency.
Meanwhile, Finey, who died in 2014, was the first-ever recipient of a BTC transaction sent from Satoshi. Also, he was identified as a possible Nakamoto ghostwriter by Newsweek and the New Yorker. In fact, shortly before his death, Forbes wrote about the fact that Finney, a cryptography pioneer, had a neighbor named Nakamoto.
Also, Adam Back, CEO of major blockchain technology firm Blockstream, was one of the first two people to receive an email from Satoshi, and he was also cited in the Bitcoin white paper.
Another computer scientist, Craig S. Wright has infamously claimed to be Nakamoto but has never been able to prove it.
Given the complexity of Bitcoin and the deep understanding of economics showcased by Nakamoto, many are of the opinion that Nakamoto was actually a group of people. Many contend that it is improbable that one person could be so well versed in many different areas of scholarship to create a technological tool so robust that it continues to stand the test of time today.
The etymology of Satoshi Nakamoto corresponds to knowledge or enlightenment and the middle or center. The vague nature of the words can mean one of two things, either awoken by being at the source or central intelligence. The latter is a much-speculated theory, that the US National Security Agency (NSA) (or some other government intelligence operation) created the cryptocurrency.
The most quoted evidence backing this theory is the fact that Bitcoin employs a common cryptography tool to create its public and private keys. The theory is that this in itself could provide the NSA with a back door to the Bitcoin blockchain.
Another reason cited by pundits of this theory is the fact that social media threads, on sites like Reddit, which question the NSA/Bitcoin connection are deleted. Finally, even Ethereum (ETH) co-founder Vitalik Buterin (before his ETH career even started) reportedly said that he wouldnt be surprised if [Nakamoto] is actually an American working for the NSA specializing in cryptography. Then he got sick of the governments monetary policies and decided to create Bitcoin. He also added: Or the NSA itself decided to create Bitcoin.
However, several years later, Buterin clarified that his opinions have changed a lot since his NSA-related statements in 2011.
Blockstream is a blockchain technology company staffed by well-known and well-regarded developers. It is led by aforementioned Adam Back, a cryptographer aligned with the cypherpunk movement. It is through these endeavors where he interacted with Satoshi Nakamoto, corresponding with him, which led to him being cited in the Bitcoin whitepaper.
Blockstream describes itself as the global leader in Bitcoin and blockchain technology. Founded in 2014, the company aims to create a range of products and services which should ease the use and adoption of bitcoin and other blockchain-based digital currencies. Blockstream has raised large amounts in its funding rounds since its inception.
To the onlooker, Blockstream should be a well-regarded institution within the space. Meanwhile, for a number within the space, Blockstream seems to be hell-bent on destroying the original intent of Bitcoin with its driving motivations being profit.
However, these accusations can be heard from the Bitcoin Cash (BCH), which is a hard fork of Bitcoin, camp mostly. They claim that Blockstream is against any changes that may scale Bitcoin because they want users to use their proprietary sidechains, such as the Liquid Network.
Given that many of the Bitcoin Core developers also work at Blockstream, this is an "interesting" accusation, to say the least. While it is an old conspiracy theory, it keeps morphing with time.
In 2018, a Danish firm called BiChip (which, ironically, seems to be spreading vaccines-related conspiracy theories by itself) released an update to their subdermal chip, allowing people to store the XRP token inside themselves. By writing the chip, users could transact with their XRP holdings. The chip has since expanded its abilities and can now be used by BTC users too.
Conservative and religious circles were quick to point out the similarities between the emerging tech and the mark of the beast.
The mark of the beast references a theme in the Book of Revelations where people in the end times will be unable to trade without having the mark of the beast, either in their hand or on their forehead. Given the subdermal nature of the chip, speculation was rife and the theory took hold quickly.
That speculation inspired even more end-time related theories, with people claiming that Bitcoin was intended to usher in the New World Order where artificial intelligence would be lord to all. The theory is that AI created Bitcoin, using the prospect of profit as a lure to trap humanity into worshipping it.
___
In either case, despite all these conspiracists, Bitcoin is about to turn 12 on January 3, the anniversary of the first block in the Bitcoin blockchain mined, and it looks ready to ignore even more and even crazier conspiracy theories going forward.
___
Learn more: Bitcoin Wheel Cannot Be StoppedCrypto in 2021: Bitcoin To Ride The Same Wave Of Macroeconomic ProblemsCrypto Adoption in 2021: Bitcoin Rules, Ethereum Grows & Faces RivalsCrypto in 2021: Institutions Prefer Bitcoin, Retail Open to Altcoins
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Sri Lankan Army to play bigger role in COVID-19 prevention – Outlook India
Posted: at 9:38 am
Colombo, Jan 1 (PTI) The Sri Lankan has appointed 25 senior officers to coordinate the COVID-19 control operations in each district amid a surge in the number of coronavirus cases.
General Shavendra Silva, the Army chief, appointed the coordinating officers for all 25 districts, each of the units headed by a Major General, the Army said.
The new Army coordinating officers at each district would facilitate smooth conduct of quarantine centres, transportation of individuals for quarantine and treatment, the supply of medicines, equipment and dry rations, the Army statement said.
Silva, who was promoted to the rank of a 4 star General last week, was appointed the head of COVID-19 prevention task force at the outset of the pandemic mid-March.
Since early October the island has seen a massive surge in confirmed coronavirus cases and deaths. The death toll from the pandemic in the country crossed the 200-mark by Thursday.
The surge was due to two new clusters reported from a garment exporting factory and at the Colombos biggest wholesale fish market.
Out of the total of 43,249 identified cases since mid-March, 39,570 had come from the two clusters. PTI CORR NSA
Disclaimer :- This story has not been edited by Outlook staff and is auto-generated from news agency feeds. Source: PTI
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Trade and policy in spotlight at webinars for sheep producers – Press and Journal
Posted: at 9:38 am
Sheep producers are invited to find out more about post-Brexit trade and future agricultural policy at a series of virtual events starting next month.
The events, organised by the National Sheep Association (NSA), will take place each Wednesday morning at 8.30am for four weeks from January 20.
With so much still to be announced on how the UKs departure from the EU will shape our future sheep industry, combined with changes to agricultural legislation and support payments, there will no doubt be many sheep farmers out there seeking some support and guidance as we start the new year, said NSA chief executive Phil Stocker.
NSA is excited to launch this new series of short webinars to help the nations sheep farmers keep up to date on the latest announcements affecting them.
We will be welcoming industry leaders from across the UK as well as NSA office holders and some of our corporate supporters to present what we hope will be engaging and useful short sessions that can be enjoyed over breakfast before the days jobs really begin.
Farmers and crofters interested in finding out more about the events are asked to register their interest online here.
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Research Roundup: Different Antibody Responses to COVID-19 and More – BioSpace
Posted: at 9:37 am
Every week there are numerous scientific studies published. Heres a look at some of the more interesting ones.
Antibodies Respond Differently to Severe Versus Mild COVID-19
Researchers at Stanford Medicine found that COVID-19 antibodies preferentially target different parts of the SARS-CoV-2 virus in mild COVID-19 cases than they do in severe cases. In addition, they fade differently based on the severity of the case. People with severe COVID-19 have low proportions of antibodies that target the spike protein. In milder cases, the antibodies seem to do a better job of binding to the spike protein. The spike protein binds to the ACE2 receptor on human cells, which allows the virus to enter the cell. Once inside, the virus gets rid of its outer coat, takes over the cells protein-making machinery and churns out more viral particles that then infect other cells. Antibodies that bind to the spike protein block the ability to bind to ACE2. Antibodies that bind to other parts of the virus dont seem to prevent viral spread.
Antibody responses are not likely to be the sole determinant of someones outcome, said Scott Boyd, associate professor of pathology at Stanford. Among people with severe disease, some die and some recover. Some of these patients mount a vigorous immune response, and others have a more moderate response. So, there are a lot of other things going on. There are also other branches of the immune system involved. Its important to note that our results identify correlations but dont prove causation.
Understanding Brain Plasticity in Adults
When brains develop, they constantly grow new neuronal connectionssynapsesas they learn and remember. Important connects are nurtured and reinforced while seemingly unnecessary ones are pruned. Adult brains undergo similar treatment, but its not well understood why adult synapses are eliminated. A group of researchers at The Korean Advanced Institute of Science and Technology (KAIST) have found the underlying mechanism of plasticity, which could be related to neurological disorders in adult brains. The brains gray matter contains microglia and astrocytes. Microglia are a frontline immune defensethey eat pathogens and dead cells. Astrocytes are star-shaped cells that help structure the brain and maintain homeostasis with involvement in neuronal signaling. It was long thought that microglial eat synapses as part of their clean-up effort, a process called phagocytosis. But their research, using a new molecular sensor, found that it was actually the astrocytes that are constantly eliminating excessive and unnecessary adult excitatory synaptic connections.
New Class of Antibiotic Works Against Range of Bacteria
Investigators with the Wistar Institute have identified a new class of antibiotics that have a broad range of antibacterial effects, including against microbes with antimicrobial resistance (AMR). They focused on a metabolic pathway essential for bacteria but absent in humans, called methyl-D-erythritol phosphate (MEP) or non-mevalonate pathway, which is responsible for biosynthesis of isoprenoids. Isoprenoids are required for cell survival in most pathogenic bacteria. The researchers targeted the IspH enzyme, essential in isoprenoid biosynthesis. They screened several million commercially available compounds using computer models to find ones that could bind with the enzyme and chose the most potent ones. Most IspH inhibitors cant penetrate the bacterial cell wall, so the researchers worked to identify and synthesize novel IspH inhibitors that could get inside the bacteria.
Rhesus Macaque Genome Reference Includes 85 Million Genetic Variants
Researchers at Baylor College of Medicine, the University of Missouri and the University of Washington created a new reference genome assembly, identifying more than 85 million genetic variants in the rhesus macaque. This makes it the largest database of genetic variation for any single nonhuman primate species. It is a big improvement over the first reference assembled in 2007, and they believe it can help analyze and answer fundamental questions in molecular genetics, cell biology and physiology, not just in rhesus macaques, but in humans and other primates and mammals.
This is a major step forward in the amount of information we have about genetic variation in the rhesus macaque, said Jeffrey Rogers, associate professor at the Human Genome Sequencing Center and Department of Molecular and Human Genetics at Baylor. We have actually identified thousands of new mutations in the population of research animals. Now colleagues all over the country who are investigating various aspects of health and disease using rhesus macaques can begin to make use of that information.
Common Diabetes Drug Linked to Rare COVID-19 Complications
Although diabetes is a known risk factor for COVID-19, researchers with Brigham and Womens Hospital have identified a rare COVID-19 complication with common diabetes drugs. The side effect is called euDKA, or euglycemic diabetic ketoacidosis. DKA occurs when the bodys cells do not absorb enough glucose and begin metabolizing fats instead, which results in a build-up of ketones. EuDKA is marked by lower blood sugar levels, making it harder to diagnose. The researchers evaluated five unusual euDKA cases that was a significantly higher level of incidence, all seen in COVID-19 patients taking sodium-glucose cotransporter 2 inhibitors (SLGLT2i). They believe that COVID-19 may increase the risk of euDKA by binding to cells on the pancreas that produce insulin. The three SGLT2 inhibitors approved by the FDA are Janssens Invokana (canagliflozin), AstraZenecas Farxiga (dapagliflozin) and Eli Lilly and Boehringer Ingelheims Jardiance (empagliflozin).
Whats Going on in the International Space Station?
The Expedition 64 crew took the day off for Christmas, but immediately afterwards went back to work on a variety of biological and medical research. Two studies evaluated new treatments for joint injuries and cancerone looked at bone, cartilage and synovium in artificial gravity chambers to better understand bone loss and joint damage; the second studied protein crystals grown in space and their ability to target cancer cells. A different study on several dozen mice evaluated the vascular changes in space on eyesight functionabout 40% of people working in space have vision changes from fluid shifts and radiation. Another experiment studied genetic changes in space and their impact on the growth and deterioration of bone tissue.
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Health and Social Care Professionals Recognised in New Year Honours – Medscape
Posted: at 9:37 am
Editor's note, 31 December 2020: This article was updated with additional recipients.
The work of more than a hundred health and social care workers during the COVID-19 pandemic has been recognised in this year's New Year Honours.
They include a British Empire Medal (BEM) for Cath Fitzsimmons from Greater Manchester, a former palliative care nurse who came out of retirement for COVID-19.
Also awarded a BEM was Dr Azeem Alam, a junior doctor at Guy's and St Thomas' NHS Foundation Trust, who founded BiteMedicine, providing free medical education for medical students during the pandemic.
An MBE went to Jacky Coping from Suffolk, a deputy director of nursing, who initiated Face Fit Testing at the James Paget University Hospitals NHS Foundation Trust to help ensure that frontline workers were properly protected against COVID-19.
Public sector workers, including medical professionals, make up 14.8% of the list mainly for the way they responded to the pandemic.
Prime Minister Boris Johnson said: "In a year when so many have made sacrifices to protect our NHS and save people's lives, the outstanding efforts of those receiving honours today are a welcome reminder of the strength of human spirit, and of what can be achieved through courage and compassion."
Prof Paul Cosford was knighted for services to public health. Prof Cosford was lately emeritus medical director for Public Health England (PHE).
He joined PHE in 2012 after leading the national and local delivery of health protection services within the Health Protection Agency.
Among others to be honoured who'll receiveMBEs were:
Captain Emma Henderson, from Moray in Scotland, for founding Project Wingman, creating a 'first class' lounge experience in hospitals in the UK for NHS workers
Dr Fiona Dempsey, consultant in intensive care medicine and anaesthesia, Somerset NHS Foundation Trust forservices to the NHS
Dr Thomas Best, clinical director critical care, King's College Hospital NHS Foundation Trust for services to critical care, particularly during COVID-19
Professor Tamas Szakmany, critical care consultant, Royal Gwent Hospital forservices to the NHS during COVID-19
Other health and social care professionals have been honoured with OBEs.
Prof Partha Kar, a consultant and endocrinologist at Portsmouth Hospitals NHS Trust, was honoured with an OBE for services to people with diabetes, and told Medscape News UK he was "humbled and grateful for all the love and support I have received from those living with diabetes".
Prof Kar, a national specialist adviser on diabetes care for NHS England, pioneered the use of continuous glucose monitoring devices in the NHS.
He added that it had been "a long way from growing up in Kolkata, India, to having one of the highest honours in the UK".
Among other OBE recipients were:
Prof Wendy Bickmore, director of the Medical Research Council's Human Genetics Unit at the University of Edinburgh
Prof Wendy Burn, president of the Royal College of Psychiatrists
Prof Ian Finlay, consultant surgeon at Glasgow Royal Infirmary
Usha Goswami, professor of cognitive developmental neuroscience at the University of Cambridge
Anthony Campbell, honorary research professor at Cardiff University
Robert Champion, founder of the prostate cancer charity, Bob Champion Cancer Trust
Dr Shikandhini Kanagasundrem, director, infection prevention and control and consultant microbiologist at the Princess Alexandra Hospital NHS Trust
Harjinder Kaur Kandola, chief executive, Barnet, Enfield and Haringey Mental Health NHS Trust, for services to mental health, particularly during the COVID-19 response
Francesca Gabrielle Happe, professor of cognitive neuroscience at King's College London, for services to the study of autism
Dr Timothy Ho, medical director at Frimley Health NHS Foundation Trust, for services to the NHS during COVID-19
Stephen Holmes, service director for adult social care at Northumberland County Council for services during the pandemic
Dr Gareth Hynes, specialty registrar at Oxford University Hospitals NHS Foundation Trust, for services to medical education during COVID-19
Dr Michael Paul Weekes, infectious diseases clinician at Cambridge University Hospitals NHS Foundation Trust
Michelle Johnson, chief nurse at the Whittington Health NHS Trust, for services to nursing, particularly during the pandemic
Sara Jane Robertson, matron at the Neonatal Intensive Care Unit at Ashford and St Peter's Hospitals NHS Foundation Trust, for services to nursing during COVID-19
Ramani Moonesinghe, professor of perioperative medicine and consultant anaesthetist, University College London for services to anaesthesia, perioperative, and critical care
Paul Charles Tunstell, associate chief pharmacist at Guy's and St Thomas' NHS Foundation Trust for services during the COVID-19 pandemic
Professor ChrisMoran,National Clinical Director for Trauma, NHS England and NHS Improvementforservices to trauma surgery
"As we begin a new year and continue to come together to fight this virus, may their service and stories be an inspiration to us all," Mr Johnson commented.
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10 things we learned about our human ancestors in 2020 – Livescience.com
Posted: at 9:37 am
Early humans left behind clues footprints, chiseled rocks, genetic material and more that can reveal our species survived and spread across Earth. These ancient people weren't so different from us; they traveled far and wide, hooked up with one another and even mined for natural resources (in this case, the reddish mineral ochre). Here are 10 things we learned about our human ancestors in 2020.
Early humans (Homo sapiens) didn't sleep with just one other. About 1 million years ago, H. sapiens had several rendezvous with another mystery species, and our species still carries some of these genes today, a study in the journal PLOS Genetics found.
It's possible this mystery species was Homo erectus, but we may never know for sure because H. erectus went extinct about 110,000 years ago, and scientists don't have any of this species' DNA.
Read more: Mystery ancestor mated with ancient humans. And its 'nested' DNA was just found.
The oldest known human DNA belongs to Homo antecessor, a species that may have practiced cannibalism. And at 800,000 years old, it's a record breaker.
Scientists found the remains of six H. antecessor individuals in Spain in 1994, but it wasn't until this year that a team of researchers extracted DNA from one of these individual's teeth, using the proteins found in the enamel to determine the segment of DNA that coded them. The team then compared this DNA sequence with recent human tooth samples, and determined that H. antecessor is not a close relation. Rather, it was likely a sister species of an ancestor that led to modern humans.
Read more: World's oldest human DNA found in 800,000-year-old tooth of a cannibal
When modern humans (Homo sapiens) left the Horn of Africa about 130,000 years ago, they trekked along the Arabian Peninsula. But which path did they take? Now, scientists have an idea, after finding sharp, human-crafted flint points in Israel's Negev Desert that are just like "breadcrumbs" marking an ancient route, according to ongoing research at the Israel Antiquities Authority.
Read more: Ancient stone 'breadcrumbs' reveal early human migration out of Africa
So, where exactly did humans walk on the Arabian Peninsula? Scientists know at least a few exact locations. Researchers have found 120,000-year-old human footprints among those of other ancient animals preserved in an ancient lakebed in the Nefud Desert of Saudi Arabia. These footprints are the earliest evidence of Homo sapiens on the Arabian Peninsula, the researchers said. During that time, the Arabian Peninsula was green and dotted with lakes, a hospitable place for migrating humans.
Read more: Prehistoric desert footprints are earliest evidence for humans on Arabian Peninsula
The first people to set foot in the Americas may have arrived 30,000 years ago, two new studies found. That's much earlier than researchers previously thought, with some scientists historically saying that the first Americans showed up as late as 13,000 years ago.
In one study, published in the journal Nature, the excavation of a remote cave in northwestern Mexico revealed human-made stone tools dating to 31,500 years ago. In the other study, also published in Nature, scientists took already-published data on early human activity in Beringia (the area connecting Russia to America during the last ice age), and entered them into an equation that modeled human dispersal. The model showed that early humans likely arrived in North America at least 26,000 years ago.
However, the Americas were sparsely populated that long ago. There wasn't a population boom until 14,700 years ago, as the last ice age was beginning to end, the latter study found.
Read more: First Americans may have arrived to the continent 30,000 years ago
Just like today, thousands of years ago the Americas were a diverse place. An analysis of four ancient skulls found in underwater caves in the Mexican state of Quintana Roo shows that these individuals looked nothing alike: one skull looked like people from the Arctic, another has European features, a third looks like early South American people and the last doesn't look like any one population.
The skulls date to between 13,000 and 9,000 years ago, just as the last ice age was ending, according to the study, published in the journal PLOS One.
Read more: Skulls from ancient North Americans hint at multiple migration waves
Those same Mexican caves, which are now underwater, hid another secret, scientists learned in 2020. For years, divers have found the skeletons of ancient people, including the skulls mentioned above. This begged the question: What were ancient people doing there in the first place?
Now, new evidence suggests some of these ancient people were miners. About 12,000 to 10,000 years ago, ancient people mined the caves for the red mineral ochre and left signs of their work, including the charred remains of fires, stone tools and stone markers so they wouldn't get lost in the pitch black maze. Ochre was used for rituals and everyday activities, including possibly as insect repellent or sunscreen.
Read more: Ice age mining camp found 'frozen in time' in underwater Mexican cave
More than 10,000 years ago, a woman carrying a toddler on her hip set down the child, readjusted, and picked up the child again as she continued her journey across the playa of what is now New Mexico.
Researchers found this woman's footprints, and those of the squirmy toddler, in White Sands National Park. At 0.9 miles (1.5 kilometers) long, this trackway is the longest late Pleistocene epoch double human trackway on record.
Read more: 10,000-year-old footprints show journey of squirmy toddler and caregiver
Four children who died young between 8,000 and 3,000 years ago in what is now Cameroon had secrets in their DNA. After analyzing the DNA from these ancient children's remains, scientists were surprised to discover a previously unknown "ghost" population of humans had contributed to these children's genomes.
About one-third of the children's DNA originated from ancestors that were closely related to known hunter-gatherers in western Central Africa, the researchers found. But the other two-thirds hailed from an ancient source in West Africa, including a "long lost ghost population of modern humans" that weren't known about until now, the scientists reported in the study, published in the journal Nature.
Nowadays, dating apps can help people find partners. But 800 years ago, the Polynesians and Indigenous people of Colombia didn't have apps they had boats, and apparently one of these groups boated to the other and hooked up.
When researchers looked at Polynesian DNA, they realized some carried a genetic signature similar to Indigenous Colombians. But it's unclear whether the Polynesians traveled to Colombia and then returned to Polynesia (with their Colombian-Polynesian children), or whether Colombians traveled to Polynesia, the researchers said.
"We can't say definitely who made contact with whom," study lead researcher Alexander Ioannidis, a postdoctoral research fellow of biomedical data sciences at Stanford University, told Live Science.
Read more: Polynesians and Native Americans paired up 800 years ago, DNA reveals
Originally published on Live Science.
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Study of More Than 1 Million People Finds Intriguing Link Between Iron Levels And Lifespan – ScienceAlert
Posted: at 9:37 am
A massive study published in 2020 found evidence that blood iron levels could play a role in influencing how long you live.
It's always important to take longevity studies with a big grain of salt, but the research was impressive in its breadth, covering genetic information from well over 1 million people across three public databases. It also focused on three key measures of ageing: lifespan, years lived free of disease (referred to as healthspan), and making it to an extremely old age (AKA longevity).
Throughout the analysis, 10 key regions of the genome were shown to be related to these measures of long life, as were gene sets linked to how the body metabolises iron.
Put simply, having too much iron in the blood appeared to be linked to an increased risk of dying earlier.
"We are very excited by these findings as they strongly suggest that high levels of iron in the blood reduces our healthy years of life, and keeping these levels in check could prevent age-related damage," said data analyst Paul Timmers, from the University of Edinburgh in the UK.
"We speculate that our findings on iron metabolism might also start to explain why very high levels of iron-rich red meat in the diet has been linked to age-related conditions such as heart disease."
While correlation doesn't necessarily mean causation, the researchers used a statistical technique called Mendelian randomisation to reduce bias and attempt to infer causation in the data.
As the researchers noted, genetics are thought to have around a 10 percent influence on lifespan and healthspan, and that can make it difficult to pick out the genes involved from all the other factors involved (like your smoking or drinking habits). With that in mind, one of the advantages of this new study is its sheer size and scope.
Five of the genetic markers the researchers found had not previously been highlighted as significant at the genome-wide level. Some, including APOE and FOXO3, have been singled out in the past as being important to the ageing process and human health.
"It is clear from the association of age-related diseases and the well-known ageing loci APOE and FOXO3 that we are capturing the human ageing process to some extent," wrote the researchers in their paper published in July 2020.
While we're still in the early stages for investigating this association with iron metabolism, further down the line we could see the development of drugs designed to lower the levels of iron in the blood - which could potentially add extra years to our lives.
Besides genetics, blood iron is mostly controlled by diet and has already been linked to a number of age-related diseases, including Parkinson's and liver disease. It also affects our body's ability to fight off infection as we get older.
We can add this latest study to the growing evidence that 'iron overload', or not being able to break it down properly, can have an influence on how long we're likely to live, as well as how healthy we're likely to be in our later years.
"Our ultimate aim is to discover how ageing is regulated and find ways to increase health during ageing," says Joris Deelenwho studies the biology of ageing at the Max Planck Institute for Biology of Ageing in Germany.
"The 10 regions of the genome we have discovered that are linked to lifespan, healthspan, and longevity are all exciting candidates for further studies."
The research has been published in Nature Communications.
A version of this article was first published in July 2020.
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