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Category Archives: Immortality Medicine
Posted: October 27, 2020 at 11:01 pm
When the New York Times and CNN recently referred to the staged town hall spectacles of Biden and Trump as dueling events, they inadvertently revealed the truth that U.S. presidential elections are Americas favorite movie and that the corporate media is in the entertainment business.
While it is ludicrous to imagine these tottering actors crossing swords in tights, their skirmishes in suits and ties are good for a few laughs, if you have the stomach to watch them. Only people who still believe in professional wrestling would think these clowns dont work for the same bosses the Umbrella People, aka the power elites, the national security state, etc., who own the country and choose their stooges to represent their interests in the White House.
I much prefer Mel Brooks, a genuinely funny guy.
The columnist Russell Baker once said the purpose of such political entertainment is to provide a manageably small cast for a national sitcom, or soap opera, or docudrama, making it easy for media people to persuade themselves they are covering the news while mostly just entertaining us.
As for debates and town hall farces in television prime time, the witty Baker said that the charm of television entertainment is its ability to bridge the chasm between dinner and bedtime without mental distraction.
Now lets proceed to the dark side, where the sardonic screams of laughter dissolve into tears.
For such entertainment serves a devious distracting purpose: to conceal the nature of social evil and the driving forces behind American politics today. It is not particularly complicated unless the syllogism All cats die/Socrates is dead/ therefore Socrates is a cat rings true.
Then its an impossible conundrum.
We are not cats or Socrates, as far as I know. But like them, we will also die. Everyone knows this, but the thought of death is not particularly have-a-nice-dayish, so people deny it as much as possible in a host of ways. Most people prefer life over death, and when death does approach and can no longer be denied, most hope for immortality in some way, shape, or form.
Yes, there are those who assert this isnt true for them, and there is no reason to doubt their sincerity. There are philosophical arguments to support their position, such as that of the Roman poet Lucretius in his famous poem De rerum natura (On the Nature of Things). But I would maintain with the great psychoanalyst Rollo May that all such naturalistic efforts, including Lucretiuss, to explain away human anxiety rooted in death, founder on the human emotions of pity, grief, love, and loneliness. Rational explanations take us only so far. In their efforts to deny the human condition and dismiss the spiritual dimension, the irrational, and the daimonic, they open the door to madness, as is happening today with the push by the worlds economic elite to convince people that they are machines and that their machine dreams will conquer death.
For those who love life, it seems axiomatic to me that some form of perpetuation and redemption of an individuals life in the face and fear of death is widely desired. This can take many forms: a literal afterlife, fame, heirs, monuments, money, children, etc. History is quite clear that people have always sought some way of transcending their physical fates.
This was aptly noted by Graham Greene, the English novelist, when, as an old man approaching death, he was asked if he was disappointed at not receiving the Nobel Prize, and he said no, since he was hoping for a greater prize.
In his important book, The Denial of Death (Pulitzer Prize 1974 for general non-fiction), the cultural anthropologist Ernest Becker, puts it succinctly:
Man is literally split in two: he has an awareness of his own splendid uniqueness in that he sticks out of nature with a towering majesty, and yet goes back into the ground a few feet in order blindly and dumbly to rot and disappear forever.
Faced with such an impossible situation, then, overwhelmed from childhood with a sense of ones own ultimate physical powerlessness but being symbolic creatures as well as physical ones, the normal person learns to repress the terror of death by building various defenses that allow one to believe that he ultimately controls his death. Ones natural impotence is then hidden within the vital lie of character; one lives within the manageable social world that helps one blot out existential awareness by offering various social games and cultural symbols, agreed forms of madness that narcotize the fear. One learns to adjust. The aim is to cut life down to manageable proportions, domesticate terror, and trust in the cultural and social authorities for protection and reassurance. Obedience is key.
Listen to Big Daddy and he will rescue you , especially when he first tells you that Mr. Pumpkin Head is coming to get you unless you run into his protective embrace.
These days, its Halloween all year round in the land of the free and the home of the brave where the fear of death is handed out like poisoned candy and Big Daddy waits at the door disguised as everyones benevolent grandfather. To be treated, you must be masked. That is his trick. Stay well, he mutters, after he drops a dollop of sweet fear into your bag and cackles behind his face.
Everywhere you look these days, people are doubly masked. The paper kind and by definition, since the the word person, being derived from the Latin, persona, means mask, while there is another Latin word, larva, that also means mask or ghost or evil spirit. Clearly there is a dance contest underway, a danse macabre. And who will win nobody knows.
Every conflict over truth, wrote the psychoanalyst Otto Rank, is in the last analysis just the same old struggle over immortality.
This is exactly what is going on now with the fierce disagreements over Covid-19.
Like the attacks of September 11, 2001, the anthrax attacks, the ginning up of terrorism fear with Homeland Securitys color-coded warning system, the lies about weapons of mass-destruction, and the coronavirus early warning systems, people have adopted positions upon which they stake their psychological lives. To admit you were snookered is a little death that is hard to swallow.
We are being subjected to mind-control on a vast scale, the continual pumping up of the fear of death to control the population. Americans have been living in an atmosphere of dread for almost twenty years. Its so old and so obvious but cuts so deep it works like a charm. You dont want to die, do you, so come here into Big Daddys arms.
In Nineteen Eighty-Four, George Orwell writes that The Party seeks power entirely for its own sake. It is a famous quote that is not true when taken out of context. The Umbrella People and their lackeys dont seek power entirely for its own sake. They have a larger agenda: immortality.
If one reads Orwell carefully, one comes upon a key passage that clarifies the previous quote. The evil OBrien, the torturer and member of the Inner Party who poses as a member of the resistance to Big Brother (sound familiar?), asks his victim Winston Smith to reverse the slogan from Freedom is Slavery to Slavery is Freedom:
Alone free the human being is always defeated. It must be so, because every human being is destined to die, which is the greatest of all failures. But if he can make complete, utter submission, if he can escape from his identity, if he can merge himself in the Party so that he is the Party, then he will be all-powerful and immortal. The second thing for you to realize is that power is power over human beings. Over the body but, above all, over the mind. Power over matter external reality as you would call it is not important. Already our control over matter is absolute.
All power is fundamentally power to deny mortality. This is true whether it is the power of the state or church. And it is always sacred power.
Many often ask why do the super-rich and powerful always want more. Its simple. They wish to transcend their pre-existing human mortality and become gods immortals. They stupidly believe that if they can lord it over others, kill, dominate, achieve status, become billionaires, presidents, magnates, celebrities, etc., they will somehow live in some weird forever.
In a process that has spanned at least a hundred and fifty years or so, our traditional cultural/religious symbol systems have been radically undermined, most momentously by the Faustian creation of Lord Nuke. All forms of symbolic immortality (theological, biological, creative, natural, and experiential) that formerly provided a sense of continuity have been severely threatened. This is the haunting specter lurking in the background of life today.
What is death? How to defeat or transcend it? How to affirm life in the face of death?
One paradoxical way that political leaders do this is by killing. Followers who accede to such killing join their leaders, not simply to see others dead, but to acquire power over death itself to kill their own deaths. It is perverse, of course, and is summed up in the saying to love the bomb joyously, to experience the nightmare of oblivion as ecstasy. Isnt this what the philosophy of voting for the lesser of two evil is about? At least he will be our killer. Our evil killer, but not as bad as yours. You lose.
I have read that there is a painting still visible at the entrance to a house in ruined Pompeii that tells us much about power and wealth. It perfectly symbolizes the meaning of the economic gap between the super-rich e.g. those behind the World Economic Forum, the CIA, the presidential candidates, the corporate media and the rest of us. It pictures a man weighing his penis on a scale of gold coins. Gold, God, wealth, and power. Its an old story.
Today, however, there is a difference, for the spirit of nihilism has grown as belief in the spiritual dimension and God has diminished dramatically. Money or gold, wealth in all its forms, is todays foremost immortality symbol, a sign that one is powerful and can conquer death. What else are Trumps gold-emblazoned Tower and hair, and Bidens boastfully admitted threat to withhold one billion dollars from Ukraine unless they fire the prosecutor investigating his son, Hunter. The greasing of palms, bribery, tax theft, etc. par for the course in a corrupt society run by thieves and criminals.
Becker says of this wealth obsession:
The only hint we get of the cultural repression seeping through is that even dedicated financiers wash their hands after handling money. The victory over death is a fantasy that cannot be fully believed in; money doesnt entirely banish feces [decay and death that is of course defeated with toilet paper as Covid-19 has proven], and so the threat of germs and vulnerability in the very process of securing immortality.
Enter Covid-19. Like the attacks of September 11, 2001, it is death writ large. An insidious terrorist threat. Invisible, sneaky, ready to pounce. Fear and trembling. So-called surprise attacks that were preceded by simulations and live drills. Numerous parallels, too many to mention. Lets not. Have a nice day! Stay safe!
So what do the super-rich controllers want now? What are the World Economic Forums Claus Schwab, Google and the Defense Departments Eric Schmidt, Bill Gates, Ray Kurzweil of Google and The Singularity, et al. pushing now that Covid-19 has so many cowering in fear?
These people have realized that the thing that their money and power must do is to create a world where trans-humanism must triumph and people of flesh and blood must be induced and forced to become the machines they have been told they are. If you doubt this is underway, research the World Economic Forums agenda, see what the Great Reset is about, the Build Back Better slogans, the massive push to create on-line existence for everyone, etc. As a recent ad I saw says: The world is going digital.
The goal of these mad technocratic elites is to create a fabricated reality where the visible world becomes nearly meaningless once the screen world becomes peoples window on the world. An electronic nothingness to replace reality as people in the industrialized countries gleefully embrace digital wraparound apparitions and the poor and vulnerable of this world suffer and die out of sight and out of mind. It is the fundamental seismic shift of our era and perhaps the greatest propaganda operation ever undertaken. A sort of end-times desperate gambit.
And it just so happens to revolve around the use of death fear to accomplish its goals.
But for the elites, there will be no death. For having realized that their stolen wealth and power can only take them so far, and they too will become food for worms, they have commandeered science and medicine to undertake their immortality projects. If medicine fails to find for them the secret of immortality, then computer science and Artificial Intelligence will, and they will be uploaded into computers and live forever in their beloved cyberspace. Digital immortality is not a joke for these people see Kurzweils (the director of engineering at Google) The Singularity, etc. for they are actually insane but hold key positions throughout the computer and biotechnology industries. Check where the super rich invest their money to confirm this. None of it is secret.
Having heeded Russell Bakers words about television offering no mental distraction between dinner and bedtime, I took to my crib early, knowing Tweedledee and Tweedledum would be dueling again, this time in what they humorously called a debate. I was surrounded by my stuffed animals that protected me and I slept safe and sound.
Upon awakening, I read that the gladiators had exchanged blows but that both were left standing for the big showdown on November 3. I also noticed that each had used the words dark winter in reference to Covid-19. Biden said one was coming and Trump said he didnt know.
Neither, of course, spoke of the Dark Winter Exercise, a senior level war game conducted on June 22-23, 2001, about a biological attack, a smallpox outbreak, the public health response, the lack of vaccines, the need for quarantine and isolation, the restriction of civil liberties, and the role of the Defense Department and the military in the response. Nor did they speak of anthrax attacks, but the Canadian researcher, Graeme MacQueen, will here fill you in on both, in case you dont know. Maybe the boys just forgot.
I am sure they didnt talk about the elements of Trumps Operation Warp Speed, but if you wish to understand how we are being gamed, Whitney Webb will tell you here.
Was there any mention of the Russians? I havent heard. They are always a kind of a solution. As my friend Joe Green has said:
All dissenting opinions are Russian. I think Socrates said that. Im paraphrasing.
Maybe many are still Waiting for the Barbarians.
This article was posted on Sunday, October 25th, 2020 at 10:20am and is filed under General, Opinion.
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Death, Money, and the Dueling Frauds: Trump and Biden - Dissident Voice
Watch ‘Fantasy Football Live’ for last-minute Week 7 news and sit-start advice – Yahoo Finance Australia
Posted: at 11:01 pm
The market is estimated to grow at a CAGR of 8. 4% during 2020-2027. The drug modelling software market is growing primarily due to increasing adoption of in-silico modelling tools in drug discovery and rising economic burden of drug discovery in North America.New York, Oct. 27, 2020 (GLOBE NEWSWIRE) -- Reportlinker.com announces the release of the report "North America Drug Modelling Software Market Forecast to 2027 - COVID-19 Impact and Regional Analysis By roduct Type ; Application, and Country" - https://www.reportlinker.com/p05978895/?utm_source=GNW Additionally, growing adoption of artificial intelligence in drug discovery and strategic activities by market players are likely to fuel the growth of the drug modelling software market during the forecast period. However, factors such as lack of data standardization are likely to restrain the growth of the market. Drug modelling has become an essential tool in the drug design process.Software-based drug discovery and development methods are playing a key role in the development of novel drugs. Software-based methods, such structure-based virtual screening, structure-based drug design, as molecular modelling, ligand interaction, and molecular dynamics, are considered to be a powerful tool for investigation of pharmacodynamic and pharmacokinetic properties of drugs.These methods are fast and accurate. They provide valuable insights of experimental findings and mechanisms of action. In addition, appropriate implementation of these techniques may help in reducing cost of drug designing and development. Traditional drug discovery and development method is capital-intensive and time-consuming.Moreover, it has high failure rates. It involves experimental screening of existing libraries of molecules followed by many rounds of chemical synthesis.The process of drug development, from the discovery of a lead compound to its commercial launch, is estimated to take around 10-15 years along with the investment of a huge amount of money. As per the Pharmaceutical Research and Manufacturers of America, the average cost to research and develop a successful drug is estimated to be US$ 2.6 billion. Moreover, only a small proportion of leads that are selected for further investigation during the initial stages of research are translated into clinical research studies. Over a period, the complexities of drug discovery have increased owing to the increasing size of biologics. As a result, there has been a direct rise in R&D expenditure in the pharmaceutical sector. As per the Pharmaceutical Research and Manufacturers of America, in 2017, biopharmaceutical companies sponsored more than 4,500 clinical trials in the US. These trials accounted for approximately US$ 43 billion; moreover, in 2017, biopharmaceutical companies in the US invested around US$ 97 billion in R&D. At present, the pharmaceutical industry is under tremendous pressure to cope with rising capital requirements in drug discovery research and avoid losses due to drug failure. In the past few years, several computational tools have been developed for the identification, selection, and optimization of pharmacological lead candidates.Currently, there are several computational approaches available for the drug discovery process. The predictive power of these tools has been proven to be very advantageous, allowing researchers to bypass the screening of billions of molecules.As a result, computational services, such as quantitative structure-activity relationship (QSAR), modelling, and computer-aided drug design (CADD), have now become an integral part of the pharmaceutical industry. Moreover, pharmaceutical companies that are focused on the development of large molecules are likely to continue outsourcing their respective drug discovery and development operations from drug modelling providers. Drugs are essential to curb COVID-19; more than 206,000 people have tragically died from the disease. In the U.S., to give the drug modelling technology a push, ImmunityBio and Microsoft collaborated to support for the research. Supporting COVID-19 vaccine and drug development is the main aim of ImmunityBios collaboration with Microsoft to leverage the latters Azure platform to create a 3D model of SARS-CoV-2s spike protein. Additionally, Research projects and innovations related to COVID-19 have ramped up quickly across the University of Michigan, spurred by doctors, public health experts, scientists, economists, and engineers; and encouraged by research leaders. With the emerging outbreak of the COVID-19 pandemic, the drug modelling market is likely to be positively impacted. In 2019, the software segment based on product type accounted for the highest share of the market.Also, the same segment is estimated to grow at the highest CAGR during the forecast period. Growth of this segment can be attributed to rise in demand for effective therapeutics and increase in drug discovery efforts of various biologics across a wide range of therapeutics. In addition, strategic activities by service providers, such as collaborations, product advancement, and product launch, in order to accelerate drug discovery timeline are further accelerating the growth of the market. A few of the major secondary sources associated with the North America drug modelling software market report include World Health Organization (WHO), OECD Health Statistics 2015, Pharmaceutical Research and Manufacturers of America, and Centers of Disease Control and Prevention (CDC). Read the full report: https://www.reportlinker.com/p05978895/?utm_source=GNW About Reportlinker ReportLinker is an award-winning market research solution. Reportlinker finds and organizes the latest industry data so you get all the market research you need - instantly, in one place. __________________________ CONTACT: Clare: email@example.com US: (339)-368-6001 Intl: +1 339-368-6001
The Weekly Round-Up #558 With Alienated #5, Empyre #5, Undone By Blood Or The Shadow Of A Wanted Man #5 & More Plus The Week In Music! – Inside…
Posted: August 19, 2020 at 1:15 am
Best Comic of the Week:
Alienated #5 Ive been impressed with this book from the beginning, but I feel like Simon Spurrier and Chris Wildgoose continue to level up with each new issue, especially this one. We are getting close to the end of this series, which is about three teenagers who end up being psychically connected to one another through an alien entity they find in the woods. Samir and Samantha have both used the alien to help explore their lingering anger at family or ex-boyfriends, but now Sam has taken control of Chip, and his anger knows no bounds. This series has been a really good exploration of the minds of young people, and while the other two move towards a better understanding of their place in the world, and their responsibility to it, its Sam, the untrusting wounded white cis male who needs to take things too far. Theres a subtlety to this that I really appreciate, and I highly recommend this book.
Empyre #5 This issue, unlike some previous ones, is pretty action filled. We learn why Teddy is acting so strangely, and get to see the Black Panther make a heroic stand against the Cotati in Wakanda (so does Wakanda need to get trashed in every third event for a reason now?). Al Ewing strikes a better balance between action and character moments (showing us Teddy and Billys wedding), while Valerio Schiti continues to make this book impressive, visually. I dont see Empyre ever being included as a classic event, but its recovering from some early lost ground.
Empyre: X-Men #3 Maybe its the three writers, or that a group of psychic X-Men that are brought to the fight on Genosha appear and disappear at random, or that Nightcrawler apparently can teleport halfway around the globe now, but this issue lost me a few times. I still dont entirely understand what the Cotati are doing on Genosha, what the mutant zombies are around for, or what role Hordeculture are supposed to play in this story. I think the biggest issue is that, at three issues in, weve now had 7 or 8 writers telling what is supposed to be a single story, in a big event version of that game people play where each one contributes the next sentence to a tale. It never works out.
Excellence #9 I love this series, but I found I got a little confused in a few spots with this issue. Spencer perhaps overplays his hand in trying to find some information in the Aegiss library, but what he does find is kind of shocking and further ratchets up the tension in this series. Brandon Thomas and Khary Randolph are doing the best work of their careers on this book, but it cant be read casually.
Immortal Hulk #36 The Leader stirs the pot quite a bit when Gamma Flight comes to take the Hulk in, but Jackie, the reporter, feels that she has a better way of solving things without escalating to more violence. Al Ewings run on this series feels very timely, and continues to be the most interesting take on the Hulk weve seen in a very long time.
Marauders #11 Its time to finally resolve whats been happening with Kate Pryde, and her inability to be resurrected in this issue, and Lockheed finally makes his way home. This is a solid issue, but its a little decompressed, and with the massive gap between issues, it was a little difficult to remember all thats been going on. I dont know if its necessary to start labelling all the X-books with the Path to X of Swords labels
Oblivion Song #26 The Kuthaal prepare to invade the Earth, and that gives Dakuul more opportunities to be brutal. Much of this issue focuses on the Kuthaal, and its only in the last few pages that we get to see Nate at all. Robert Kirkman and Lorenzo De Felici are in the process of switching things up on this book, and taking the excitement to a new level. I really love this title, which is unpredictable and very cool looking.
Star Wars: Darth Vader #4 Vader is on a hunt to discover how Padm hid Lukes existence from him, and that has taken him to Naboo, where he keeps coming across all the people that knew her in her life, which at this point is at least eighteen years prior. I keep waiting for someone to raise how weird and inappropriate Anikin and Padms relationship was, given that she was at least ten years older than him and knew him when he was a child, but it doesnt come up, Instead, we see some great scenes of Vader fighting monsters and decent people. Rafaelle Iencos art makes this series a must-buy.
Undone by Blood or The Shadow of a Wanted Man #5 Im really happy to see that this title will be returning in the future, with a new alternate title, and will continue to draw a parallel between the gunslinger novel featured in the story and the more contemporary main story. This series, by Zac Thompson, Lonnie Nadler, and Sami Kivel, has a Stray Bullets vibe to it (man, I miss that series), and that doesnt shy away from some pretty dark places. This arc ends with the girl finally confronting her familys killers, although it doesnt seem like the retribution shes been seeking provides her with any real sense of closure. Ive been increasingly impressed with Aftershocks lineup this year, and look forward to more Thompson/Nadler work from them.
Vampirella #12 One of the cooler things about Christopher Priests run with Vampirella has been his use of a cranky psychiatrist, Dr. Chary, as a POV character and frame for the story. In this issue, as he digs a little more into Vampirellas mother, Liliths, history, he becomes a part of the story. I still have no idea if Priest is staying faithful to previous runs with this character, or if this is a massive reboot for her, but I dont really care, as I find this run to be fantastic.
X-Force #11 The citizens of Krakoa are still dealing with some of the fallout of the first attack that X-Force had to fight off, as the genetically modified soldiers that attacked them are basically Trojan Horses for another threat. Mixed into this is Colossuss reluctance to continue fighting all the time. I like Peter a lot, and its nice to see him get some use. One of my complaints about all of the Dawn of X books is that they dont leave enough space for character moments and work. Everyones so secure in their immortality, that its only the former villains who have any reason to grow as people (this is not just this title, but its something I was thinking about as we saw a few more main and secondary characters go down once again).
Amazing Spider-Man #46
Detective Comics #1025
Dr. Strange: Surgeon Supreme #2-4 It feels like Mark Waid got the mix right with this newest Dr. Strange series, abandoning his outer space adventures for a focus on Stephen reentering medicine, and having to juggle his duties to his patients with his mystical duties. Kev Walker is just the right artist for the stories that Waid has chosen to tell, as he has Strange battling a demon that uses tattoos to eat the souls of people, and has Doctor Druid scrubbing in to assist with a demonic suicide bomb. Its a very cool take on Strange.
Keleketla! Keleketla! Ninja Tune founders Coldcut travelled to South Africa to record this album with a variety of musicians and vocalists, and then added additional music from the London jazz scene and horns from New Yorkers Antibalas. The result is a very lush album full of beats and polyrhythms that reminds me a little of the late 90s fashion for globalized electronic music. Parts of this album sound like vintage Trans-Global Underground, but it comes off as fresh, new, and as impressive as its list of contributors.
Derrick Hodge Color of Noize Derrick Hodge first came to my attention as Robert Glaspers bass player, and while Glasper doesnt appear on this album, his influence is everywhere. This is a very nice, chill album.
GoGo Penguin GoGo Penguin This British trio deliver once again with their signature spaced out approach to beat-oriented jazz. This is a great album to disappear into.
Adrian Younge, Ali Shaheed Muhammad, and Roy Ayers Jazz is Dead 002 I love the Jazz is Dead series, which has Midnight Hour and Luke Cage soundtrack stars Younge and Muhammad collaborating with jazz greats. On this one, they work with vibraphonist Roy Ayers to produce some beautiful vibes.
Tags: The Weekly Round-Up
Posted: July 15, 2020 at 9:52 pm
Netflix kicks back with another international action thriller, The Old Guard, which you likely thought would resemble its previous Hemsworth-athon, Extraction, but realized was actually closer to The Expendables meets Interview with the Vampire. Confusing genre. Still some pretty decent action. (Can we get a Charlize Theron and Chris Hemsworth movie now, please? Our fight money is on Theron.)
The Old Guard, based on the graphic novel written by Greg Rucka and illustrated by Leandro Fernandez, follows a group of immortal soldiers who heal Wolverine-style (though its unclear how they overcome explosions or missing limbs; do they, like, grow them back?). The power arrives randomly during an individuals life and also disappears randomly, or when the plot calls for it. The disappearance is supposed to mean something, but seems to only mean someone is getting ... old.
Age becomes, then, a salient talking point throughout the film. We learn that two characters were vampire bittener, we mean, immortalizedsometime during the Crusades (so, anywhere between 1095 and 1492, though likely closer to the First Crusades). Another character became immortalized in the 19th century. And then theres Andy, also referred to as Andromache of Scythia.
Andy is the oldest known soldier. She doesnt remember exactly when she first realized her immortality, which seems odd.
The Old Guard Book One: Opening Fire
(Other questions Does time move slower for Andy since shes so old? Does her brain stay its age forever, and if so wouldnt she also be super smart and not just good at killing? And if you are super smart, why keep killing if all you want is to better humanity? Couldn't you learn everything there is to know about medicine and just, like, do experiments for hundreds of years? Also, why abandon Quynh when you have literally centuries to find her, and those Spanish ships couldnt have gone THAT far out to sea? And can you really drown forever if your lungs are still full of water? Wouldnt you just stay asleep?) We digress
The hint is in that word "Scythia," which Copley mentions toward the end of the film. The word also appears during the bulletin board credits.
Scythia was a nomadic empire located across much or Eurasia in what is now Ukraine, Russia, and Crimea. Like the Mongols, the Scythians were revered for their horse-riding and warring. Historians trace the Scythians as far back as the 8th century BCE. That would be almost 3,000 years ago, making Andy very old. The empire collapsed at the hands of the Sarmatians before 200 CE.
Theron's Andy is, therefore, anywhere from 3,000 to about 1,800 years old.
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How Old Is Andy in The Old Guard? - Charlize Theron Character Age - Men's Health
Posted: at 9:52 pm
Improving immunity with Ayurveda: 5 herbs to help your body fight diseases  |  Photo Credit: iStock Images
New Delhi: Ever since the coronavirus pandemic began, talks about immunity and health became a common subject. Experts recommended that with no existing cure or vaccine for the virus, prevention techniques such as social distancing, wearing masks, practicingproper hand and respiratory hygiene, along with trying to stay as healthy as possible were the only ways to beat the virus and avoid getting sick.
This is when Indians turned to the centuries-old wisdom of Ayurveda for boosting their immunity and keeping free of diseases. As the world starts to adopt Ayurvedic practices and Yoga for overall health, and as Ayurveda moves to a global level in the fight against COVID-19 with clinical trials and research, here are 5 ayurvedic herbs that are close to home and easily available, that you can use to boost immunity and ward off diseases.
Disclaimer: Tips and suggestions mentioned in the article are for general information purposes only and should not be construed as professional medical advice. Always consult your doctor or a professional healthcare provider if you have any specific questions about any medical matter.
For full coverage on Coronavirus pandemic, click here.Join the Times Group initiative #MaskIndia.Share a picture with your home-made mask on your social handles using #MaskIndia. The best picture will be featured in TOI and on maskindia.com
AgeX Therapeutics and Pluristyx Announce Manufacturing, Marketing, and Distribution Agreement to Expand Access to Clinical-Grade Human Pluripotent…
Posted: June 17, 2020 at 12:45 am
ALAMEDA, Calif. & SEATTLE--(BUSINESS WIRE)-- AgeX Therapeutics, Inc.. (AgeX: NYSE American: AGE), a biotechnology company developing therapeutics for human aging and regeneration, and Pluristyx, Inc. (Seattle, WA), an advanced therapy tools and services company serving customers in the rapidly growing fields of regenerative medicine and cellular and gene therapies, today announced they have entered into a Manufacturing, Marketing, and Distribution Agreement through which Pluristyx will undertake these activities on behalf of AgeX with respect to AgeXs research- and clinical-grade ESI brand human embryonic stem cells, sometimes referred to as hESCs.
The agreement builds on Pluristyxs strategy to manufacture, market, and distribute high-quality standardized Ready-to-Use and Ready-to-Differentiate pluripotent stem cells to industry and academic scientists intent on developing therapeutic products to treat human disease. AgeXs ESI hESC lines are distinguished for being the first clinical-grade hESC lines created under current Good Manufacturing Practice (cGMP). The AgeX ESI hESC lines are listed on the National Institutes of Health (NIH) Stem Cell Registry and are among the best characterized and documented stem cell lines available worldwide.
The agreement is a key step in AgeXs licensing and collaboration strategy to facilitate industry and academic access to its hESC lines, its PureStem cell derivation and manufacturing platform, and its UniverCyte immunotolerance technology in order to generate near- and long-term revenues.
A recent FDA IND clearance for a biotech company to begin a human trial for a cell therapy candidate derived from an AgeX ESI hESC line has amplified interest from industry and academia to utilize our cells in regenerative medicine. It is AgeXs goal to make its cell lines the gold standard when it comes to therapeutic products derived from pluripotent stem cells. We are delighted to be working with the Pluristyx team given their extensive cGMP manufacturing experience with pluripotent stem cells, said Dr. Nafees Malik, Chief Operating Officer of AgeX.
Pluristyx is excited to be working with AgeX and their ESI hESC lines. As AgeX intends to make their cell lines the gold standard, our aim is to disrupt and redefine stem cell therapy manufacturing with our proprietary, high-density format, Ready-to-Use and Ready-to-Differentiate hESC lines, which will dramatically reduce both cost and time in translating revolutionary therapies from bench to bedside, said Dr. Benjamin Fryer, CEO of Pluristyx.
Academic and biopharma organizations will need to obtain separate commercial licenses from AgeX in order to advance their cellular product candidates generated from AgeX hESC lines into human clinical trials and commercialization. AgeX retains all rights to manufacture its own in-house cellular products as well as to extend license rights to other third parties.
About AgeX Therapeutics
AgeX Therapeutics, Inc. (NYSE American: AGE) is focused on developing and commercializing innovative therapeutics for human aging. Its PureStem and UniverCyte manufacturing and immunotolerance technologies are designed to work together to generate highly defined, universal, allogeneic, off-the-shelf pluripotent stem cell-derived young cells of any type for application in a variety of diseases with a high unmet medical need. AgeX has two preclinical cell therapy programs: AGEX-VASC1 (vascular progenitor cells) for tissue ischemia and AGEX-BAT1 (brown fat cells) for Type II diabetes. AgeXs revolutionary longevity platform induced Tissue Regeneration (iTR) aims to unlock cellular immortality and regenerative capacity to reverse age-related changes within tissues. AGEX-iTR1547 is an iTR-based formulation in preclinical development. HyStem is AgeXs delivery technology to stably engraft PureStem cell therapies in the body. AgeXs core product pipeline is intended to extend human healthspan. AgeX is seeking opportunities to establish licensing and collaboration arrangements around its broad IP estate and proprietary technology platforms and therapy product candidates.
For more information, please visit http://www.agexinc.com or connect with the company on Twitter, LinkedIn, Facebook, and YouTube.
Established in 2018, Pluristyx Inc. is a privately held, early-stage company providing a complete cell manufacturing solution. As an advanced therapy tools company, Pluristyx helps companies and researchers solve manufacturing challenges in the field of drug development, regenerative medicine, and cell and gene therapy. Pluristyx is led by a team with decades of industry experience each with specific expertise in key areas needed to develop and manufacture pluripotent stem cells. Pluristyx provides know how in every stage of the process from cell banking through scale-up of clinical grade material as well as all aspects of process development and manufacturing.
For more information, please visit http://www.pluristyx.com or connect with the company on Twitter and LinkedIn.
Forward-Looking Statements for AgeX
Certain statements contained in this release are forward-looking statements within the meaning of the Private Securities Litigation Reform Act of 1995. Any statements that are not historical fact including, but not limited to statements that contain words such as will, believes, plans, anticipates, expects, estimates should also be considered forward-looking statements. Forward-looking statements involve risks and uncertainties. Actual results may differ materially from the results anticipated in these forward-looking statements and as such should be evaluated together with the many uncertainties that affect the business of AgeX Therapeutics, Inc. and its subsidiaries, particularly those mentioned in the cautionary statements found in more detail in the Risk Factors section of AgeXs most recent Annual Report on Form 10-K and Quarterly Report on Form 10-Q filed with the Securities and Exchange Commissions (copies of which may be obtained at http://www.sec.gov). Subsequent events and developments may cause these forward-looking statements to change. In addition, with respect to AgeXs Manufacturing, Marketing and Distribution Agreement with Pluristyx there is no assurance that (i) Pluristyx will generate significant sales of AgeX ESI hESC lines, or (ii) AgeX will derive significant revenue from sales of ESI hESC lines by Pluristyx. AgeX specifically disclaims any obligation or intention to update or revise these forward-looking statements as a result of changed events or circumstances that occur after the date of this release, except as required by applicable law.
View source version on businesswire.com: https://www.businesswire.com/news/home/20200616005377/en/
Posted: at 12:45 am
Food Flashexplores the wild world of food news, from the health benefits of red wine to why dark chocolate is actually good for you.
Our favorite foods all have a shelf life, but did you know that many of them are living far beyond their original expiration date?
Thanks to artificial preservatives, fruits, vegetables, meats and dairy products last much longer now than they naturally would, and that is not necessarily good news.
Not all preservatives are bad for you, of course. Humans have been using natural preservatives like salt and sugar for thousands of years to keep food from spoiling,
Be cautious with artificial preservatives, though. According to Healthline, many of them can have harmful effects on your health.
Sulfites, for example, are used to prevent discoloration, but they have been linked to asthma.
Sodium benzoate is found in sodas and used in fermentation, but its also considered a carcinogen.
Nitrite, another carcinogen, gives hot dogs their unique red color.
Try avoiding preservatives as much as you can by shopping for organic, fresh and naturally labeled products.
If you enjoyed this story, you might also like reading abouthow our favorite foods of today have a secret past.
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The post Avoid eating these artificial preservatives whenever possible appeared first on In The Know.
Posted: June 13, 2020 at 12:53 am
So lets do a non-coronavirus post for the weekend. Over the years, Ive sporadically reported on the (rather contentious) field of aging and its biochemical implications. Many readers will recall the results of the past few years that claim that infusion of young-animal plasma into aged animals seems to have many beneficial effects. Of course, this field is well stocked with controversy. Not everyone believes the results, from what I can see (although, for what its worth, there seem to be an increasing number of papers on it). If theyre real, not everyone thinks that they can be readily extrapolated to humans. And even if they can, it doesnt take very much thought to see a number of ethical implications as well.
There have been a couple of recent papers that will stir things up even more. This preprint from a multinational research team (UCLA and many others) details work on several methylation clocks of molecular aging. DNA is methylated (especially on cytosine residues) to a number of transcriptional effects, and the number and distribution of such methyl groups definitely change over the lifespan of most animals. The Horvath lab at UCLA has made a specialty out of this epigenetic research area for some years now, and the changes in DNA methylation with aging seem pretty well established (even if quantifying them is trickier). This new paper draws on a large number of rat samples, with an overall methylation clock detailed, as well as more specific ones for brain, liver, and blood tissue. The addition of an even larger set of human tissue samples provides two more cross-species methylation clocks as well. Previous work from the group has provided similar clocksfor mice, which correlate well with known lifespan-extending interventions such as caloric restriction (reviewed here).
This new preprint details the readouts of such clocks after treatment of two-year-old rats (and their various tissues) with a proprietary plasma preparation from a company called Nugenics Research (update: corrected spelling of the name). I dont think thats going to make publication of this paper in a journal any easier, because that preparation is resolutely not described in any detail at all in the paper, from what I can see. This is no indictment of the paper or its results, but it does make them rather difficult to reproduce, doesnt it? Two of the papers authors are founders and/or owners of Nugenix, and Horvath and another author are consultants for the company (all this, to be sure, is stated in detail).
At any rate, the effects of the plasma preparation on both the methylation signatures and on more traditional readouts of physiological function seem to be pretty dramatic, after two rounds of treatment in elderly rats. By the DNA methylation clock, the ages of the blood, heart, and liver tissue were basically halved (there was much less effect on the hypothalamus, interestingly). Markers of inflammation and oxidative stress went down significantly in the treated animals, and many other blood parameters changed for the better as well (HDL, creatinine, and more). The animals performed better in physical and cognitive tests (grip strength, maze test) with numbers approaching that of the young animals themselves. The authors say that this work supports the notion that aging can be systemically controlled, at least in part through the circulatory system with plasma as the medium.
Meanwhile, this paper has also just come out, which looks at whether such effects are due to factors coming in from the young animals or things being removed from the old ones. The authors, from UC-Berkeley and the California Pacific Medical Center, are looking at what they call a neutral blood exchange. They replace half the blood volume in mice (both young and old) with isotonic saline plus added albumin protein. The effect of this on the older animals was also significant, with noticeable improvements in wound-healing ability, neurogenesis, and fibrosis/fatty deposits in the liver. The younger mice were not really changed by the treatment. The authors tried several control experiments to make sure that this wasnt an effect being driven by added albumin protein, and it apparently isnt. They conclude that removal and substitution of old plasma is sufficient for most if not all observed positive effects on muscle, brain and liver in parabiosis-type experiments. It doesnt exclude the idea of there being beneficial factors in young plasma, but suggests that this is not the driver of many of the results seen. (It would be very interesting to check the DNA methylation status of various tissues before and after this treatment!)
The paper wastes no time in noting that therapeutic plasma exchange (TPE) is already an FDA-approved process (as witness convalescent plasma treatment in the current coronavirus epidemic), and it says that Phase II and III human trials are being planned on the basis of these results.That will be quite interesting to watch, says the 58-year-old dude writing this blog. Overall, I still find such results hard to believe, but at the same time they seem to be showing up from multiple experiments. This second paper especially seems to be a very testable hypothesis indeed. Thats a good thing, because in the end, its going to be reproducible human clinical data that decide whether this is real or not so Im glad that feasible experiments will allow such data to be collected. Something to watch. . .
See the original post:
Young Blood and Old Blood | In the Pipeline - Science Magazine
Posted: at 12:53 am
By Rabbi Dr. Michael Leo Samuel
CHULA VISTA, California Jews have always possessed this ability to reorient themselves to the challenges of a changing world. Our ancestors demonstrated a certain toughness when it came to survival. Mark Twain expressed this idea best in 1897:
But nowadays, here in the United States, I am seriously beginning to doubt whether the American Jew has what it takes to survive as a minority faith in our country.
On May 30th, 2020, the nation witnessed a spectacle that was reminiscent of the time Hitler and his brownshirts seized power in Germany. As my fellow writer, Bruce S. Ticker observed in his penetrating article, Rioting in Los Angeles was an anti-Jewish pogrom for San Diego Jewish World, The Jews of the Fairfax neighborhood of Los Angeles were exposed to a modern, American-style pogrom on May 30 that should enrage us all. Not only were Jewish businesses sacked but five synagogues and three Jewish schools were reportedly vandalized in George Floyds name by thugs. Ticker drew inspiration from Daniel Greenfield, who wrote on his blog, One small business owner described a Late Saturday night with people driving down the Fairfax district streets screaming effing Jews.
Close your eyes.
Imagine listening to the sound of broken glass.
Can you visualize the horror the peaceful Jewish community of Fairfax experienced?
With the eye of your imagination, think back to the date of November 9-10, 1938, when the German paramilitary led their thugs to initiate a pogrom against the German Jews throughout Nazi Germany, as the German population looked on. Some were cheering, most were probably shocked, and others chose not to get involved.
Now open your eyes to our present.
This time, the pogrom took place in the Fairfax neighborhood of Los Angeles. And the local Jewish reaction?
Jewish leaders have gone out of their way to show support for the wrongful death of George Floyd. This is very understandable.
But our fellow Jews have gone out of their way to show complete solidarity with the Black Lives Matter movement, ignoring the fact this movement calls Israel an Apartheid State and in a manifesto, accuses Israel of perpetuating a genocide against the Palestinians. In addition, Jews are considered racist by virtue of being white.
And the Jewish reaction?
Call it Silence of the Lambs.
One local rabbinical colleague, whose name I will keep anonymous, claimed that we must honestly and genuinely address the root causes of the local protests the inequity in enforcement and the systemic racism.
I must take issue with my esteemed colleague.
The conflation of looting and peaceful protests is antithetical to one another. The looting in many of the countrys inner cities have harmed Black and other minority businesses. Several Black officers have been shot by the militant anarchists.
Did their lives matter?
Lets be honest. Many of those who scream, Black Lives Matter are among the most racist people you can find in our country. They have demonstrated by their words and by their deeds, they do not care about their fellow Black Americans. This is a movement that has done nothing to address the problems of Black on Black murders. In cities like Chicago, sometimes hundreds of innocent people are gunned down by their fellow Blacks.
Apparently, the inner citys Black lives, do NOT matter.
Until the social activists start addressing their legitimate grievances at the leaders who continue to exploit their communitys misery, it is doubtful there will be any kind of meaningful change. Black Lives Matters is a movement that continues to demonize white people for their skin color. Throughout this past week, one could see white Americans admitting they are racist because of their skin-color; some paraded wearing chains, to be yoked like animals.
What can be more racist than that?
The Reverend Martin Luther King Jr., who condemned this type of behavior throughout, had this to say:
Hillel used to say, , . , . , If I am not for myself, who is for me? When I am for myself only, what am I? And if not now, when? Jews can be active in helping other minorities by championing civil rights.
But we cannot turn a blind eye to this retrograde form of anti-Semitism that exists in the Black community.
And the rest, my friends, is commentary.
*Rabbi Michael Leo Samuel is spiritual leader of Temple Beth Shalom in Chula Vista. He may be contacted via firstname.lastname@example.org
Posted: at 12:53 am
I have been posting about using American poetry as primary historical sources, and last time, I talked about Wallace Stevenss Sunday Morning. That appeared in 1915, in an era of extraordinary social, religious and political ferment. Today Ill discuss another work from that same year, which is famous as a name, but when you actually explore it, it offers some treasures for the historian.
I am referring to Edgar Lee Masters (1868-1950), and his Spoon River Anthology, which endlessly repays close reading for its assumptions about the everyday lives and beliefs of ordinary Americans. The couple of hundred poems within the collection are interlaced to form a perfect community portrait. This really is the Great American Novel That Never Was. It has been said that no other volume of poetry except The Waste Land (1922) made such an impact during the first quarter of [the 20th] century.
Each poem its way stands as a short story, which speaks volumes about community assumptions. The Anthology is a goldmine for social history of all kinds, including gender, sexuality, politics, and religion. You actually could teach a whole course about early twentieth century America with this as the core text, and it would fit beautifully into a typical college offering on the era 1877-1919 or so.
In a time of tight censorship, Masters was boldly going into many topics that were deeply sensitive, including (and not limited to) rape, child abuse, abortion, drug abuse, adultery, promiscuity, and sexual diseases. Virtually every poem gets into some issue that would have attracted the wrath of the Hays Code if it had ever found its way into the later cinema. Here is the whole of Julia Miller:
We quarreled that morning,For he was sixty-five, and I was thirty,And I was nervous and heavy with the childWhose birth I dreaded.I thought over the last letter written meBy that estranged young soulWhose betrayal of me I had concealedBy marrying the old man.Then I took morphine and sat down to read.Across the blackness that came over my eyesI see the flickering light of these words even now:And Jesus said unto him, VerilyI say unto thee, To-day thou shaltBe with me in paradise.
Just to take one daring theme of countless, Masters was writing during the first great American discovery of child sexual abuse. Back in 1998 I published a book called Moral Panic: Changing Concepts of the Child Molester in Modern America (Yale), which offered a wide-ranging history of that theme throughout American history. Among my discoveries, I found the first ever study ever written on the topic in the US, in a collection entitled A System of Legal Medicine (1894). This included a path-breaking essay on Indecent Assault of Children, by the young gynecologist W. Travis Gibb (1863-1939), which reads as if it could have been written a century later.
Over the next quarter century or so, Americans became firmly conscious of the sexual abuse threat in a way they would not be again until the 1980s. Also as in the 1980s, awareness of that threat was firmly linked to feminist causes and agitation. And if I want to illustrate that concern, how better to do so than to use Spoon River? Here is the wrenching Nellie Clark:
I was only eight years old;And before I grew up and knew what it meantI had no words for it, exceptThat I was frightened and told myMother; And that my Father got a pistolAnd would have killed Charlie, who was a big boy,Fifteen years old, except for his Mother.Nevertheless the story clung to me.But the man who married me, a widower of thirty-five,Was a newcomer and never heard itTill two years after we were married.Then he considered himself cheated,And the village agreed that I was not really a virgin.Well, he deserted me, and I diedThe following winter.
Ye young debaters over the doctrine Of the souls immortality I who lie here was the village atheist, Talkative, contentious, versed in the arguments Of the infidels. But through a long sickness Coughing myself to death I read the Upanishads and the poetry of Jesus. And they lighted a torch of hope and intuition And desire which the Shadow, Leading me swiftly through the caverns of darkness, Could not extinguish. Listen to me, ye who live in the senses And think through the senses only: Immortality is not a gift, Immortality is an achievement; And only those who strive mightily Shall possess it.
Note the assumption that in the early twentieth century, in a small mid-Western town, a very ordinary person had access to all the arguments of the militant anti-religious writers, the infidels, not to mention the (Hindu) Upanishads. He appreciates Jesuss own words, which he originally read as poetry not revelation. The coughing reference sadly has a strong relevance today.
Less fortunate was the outspoken anti-religious militant and amateur Bible critic, Wendell P. Bloyd. Jailed for blasphemy, Bloyd was then locked up as insane, and beaten to death by a Catholic guard.
I fight the temptation to quote every last poem here, but just one more, please. In 1915, Americans were deeply divided over the thought of intervening in Europes Great War. Masters was obviously thinking of this in his poem about the Philippine war veteran, Harry Wilmans:
I was just turned twenty-one, And Henry Phipps, the Sunday-school superintendent, Made a speech in Bindles Opera House. The honor of the flag must be upheld, he said, Whether it be assailed by a barbarous tribe of Tagalogs Or the greatest power in Europe. And we cheered and cheered the speech and the flag he waved As he spoke. And I went to the war in spite of my father, And followed the flag till I saw it raised By our camp in a rice field near Manila, And all of us cheered and cheered it. But there were flies and poisonous things; And there was the deadly water, And the cruel heat, And the sickening, putrid food; And the smell of the trench just back of the tents Where the soldiers went to empty themselves; And there were the whores who followed us, full of syphilis; And beastly acts between ourselves or alone, With bullying, hatred, degradation among us, And days of loathing and nights of fear To the hour of the charge through the steaming swamp, Following the flag, Till I fell with a scream, shot through the guts. Now theres a flag over me in Spoon River. A flag! A flag!
Have you ever read accounts of how US soldiers went off to war in 1917 expecting the experience to be romantic and idealistic, with no idea of the realities they would be facing? Uh-huh. If something like Harry Wilmans had appeared a decade later, we would immediately attribute it to Lost Generation disillusion.
Its interesting, or depressing, to note that when the US actually entered the Great War in 1917, Masters yielded to nobody in his exalted rhetoric about the mystical experiences that young men would face in the approaching combat. In that movement from his earlier positions, he shared the trajectory of a great many other liberals, pacifists, and specifically religious believers in that short time span between 1915 and 1917.
Spoon River Anthology offers a wonderfully readable portrait of American society around 1915, and very much from the grass roots. Its well worth reading, and citing.
Read this article:
Writing History on the Banks of Spoon River - Patheos