Monthly Archives: March 2020

Global AYUSH and Alternative Medicine Market 2020 by Manufacturers, Regions, Type and Application, Forecast to 2025 has been prepared based on an in-depth market analysis that provides historical data from 2014 to 2019 along with a forecast from 2020 to 2025. The report covers the market landscape, analysis of the global AYUSH and Alternative Medicine market, regional and global level analysis of the market, and its growth prospects over the coming years. The report has discussed the key vendors operating in this market. The research report includes drivers and restraints and study of opportunities available in the market. Key vendors are adopting new technologies to enable major transformations in R&D. Analysts have also added a competitive landscape and an analysis of Porters Five Forces model for the market.

DOWNLOAD FREE SAMPLE REPORT:https://www.fiormarkets.com/report-detail/411461/request-sample

The report classifies the global AYUSH and Alternative Medicine market based on their definitions. The report encompasses a market attractiveness analysis, as well as all the segments, are benchmarked based on their market size, growth rate, and general attractiveness. Upstream raw materials, equipment, and downstream consumer analysis are also carried out. In this report, development trends and marketing channels are also analyzed. It further presents an intensive study of the market stature (revenue), market share, key market segments, distinct geographic regions, main market players, and prime industry trends.

Key Players Featuring In the Market:

The global market report covers particular aspects of the global AYUSH and Alternative Medicine market including the product classification, product details, scope of uses and major geographical producing regions. The report presents detailed insights about each market player, including SWOT analysis, main market information, market share, revenue, pricing, and gross margin. Prominent players are covered in this research report with comprehensive detailing.

READ FULL REPORT:https://www.fiormarkets.com/report/global-ayush-and-alternative-medicine-market-2020-by-411461.html

Leading companies reviewed in the global AYUSH and Alternative Medicine marketreport are:Baidyanath, Patanjali, Himalya Herbals, Ganga Pharmaceuticals, Hamdard,

Regional segment analysis:

Crucial Insights In Market Research:

Furthermore, the report has covered the aspect that triggers and restricts the growth of the global AYUSH and Alternative Medicine market. The study additionally displays data about developing markets, beneficial markets, static markets, declining markets, develop advertises along with development benefits. In addition, sort wise and application wise consumption figures also are given. The report will provide an in-depth analysis of future prospects as well as market penetration.

Customization of the Report:This report can be customized to meet the clients requirements. Please connect with our sales team ([emailprotected]), who will ensure that you get a report that suits your needs. You can also get in touch with our executives on+1-201-465-4211to share your research requirements.

Go here to read the rest:

Global AYUSH and Alternative Medicine Market 2020 by Company, Regions, Type and Application, Forecast to 2025 - Galus Australis

Market Research Intellect recently published a report titled Complementary And Alternative Medicine Market Size and Forecast to 2026. The report includes an authentic and accurate research study into the global Complementary And Alternative Medicine market based on a qualitative and quantitative assessment by leading industry experts. The report highlights the current market scenario and how it is likely to change in the future. This report examines growth determinants, micro and macroeconomic indicators, opportunities, developments and key market trends that are likely to have a major impact on global market growth for Complementary And Alternative Medicine.

The Global Complementary And Alternative Medicine Market is growing at a faster pace with substantial growth rates over the last few years and is estimated that the market will grow significantly in the forecasted period i.e. 2019 to 2026.

This report includes the following Companies; We can also add other companies you want:

Complementary And Alternative Medicine Market: A Competitive Perspective

The report also provides an in-depth analysis of the competitive landscape and behavior of market participants. In this way, market participants can familiarize themselves with the current and future competitive scenario of the global market for Complementary And Alternative Medicine and take strategic initiatives to gain a competitive advantage. The market analysts have carried out extensive studies using research methods such as PESTLE and Porters Five Forces analysis. Overall, this report can prove to be a useful tool for market participants to gain deep insight into the global market for Complementary And Alternative Medicine and to understand the main perspectives and ways to increase their profit margins.

Complementary And Alternative Medicine Market: Drivers and Limitations

The report section explains the various drivers and controls that have shaped the global market. The detailed analysis of many market drivers enables readers to get a clear overview of the market, including the market environment, government policy, product innovation, development and market risks.

The research report also identifies the creative opportunities, challenges, and challenges of the Complementary And Alternative Medicine market. The framework of the information will help the reader identify and plan strategies for the potential. Our obstacles, challenges and market challenges also help readers understand how the company can prevent this.

Complementary And Alternative Medicine Market: Segment Analysis

The report section contains segmentations such as application, product type and end user. These segments help determine which parts of the market will improve over others. This section analysis provides information on the most important aspects of developing certain categories better than others. It helps readers understand strategies to make solid investments. The market for Complementary And Alternative Medicine is segmented according to product type, applications and end users.

Ask for Discount @ https://www.marketresearchintellect.com/ask-for-discount/?rid=174144&utm_source=WN&utm_medium=888

Complementary And Alternative Medicine Market: Regional Analysis

This section of the report contains detailed information on the market in different regions. Each region offers a different market size because each state has different government policies and other factors. The regions included in the report are North America, Europe, Asia Pacific, the Middle East and Africa. Information about the different regions helps the reader to better understand the global market.

Table of Content

1 Introduction of Complementary And Alternative Medicine Market

1.1 Overview of the Market1.2 Scope of Report1.3 Assumptions

2 Executive Summary

3 Research Methodology of Market Research Intellect

3.1 Data Mining3.2 Validation3.3 Primary Interviews3.4 List of Data Sources

4 Complementary And Alternative Medicine Market Outlook

4.1 Overview4.2 Market Dynamics4.2.1 Drivers4.2.2 Restraints4.2.3 Opportunities4.3 Porters Five Force Model4.4 Value Chain Analysis

5 Complementary And Alternative Medicine Market , By Deployment Model

5.1 Overview

6 Complementary And Alternative Medicine Market , By Solution

6.1 Overview

7 Complementary And Alternative Medicine Market , By Vertical

7.1 Overview

8 Complementary And Alternative Medicine Market , By Geography

8.1 Overview8.2 North America8.2.1 U.S.8.2.2 Canada8.2.3 Mexico8.3 Europe8.3.1 Germany8.3.2 U.K.8.3.3 France8.3.4 Rest of Europe8.4 Asia Pacific8.4.1 China8.4.2 Japan8.4.3 India8.4.4 Rest of Asia Pacific8.5 Rest of the World8.5.1 Latin America8.5.2 Middle East

9 Complementary And Alternative Medicine Market Competitive Landscape

9.1 Overview9.2 Company Market Ranking9.3 Key Development Strategies

10 Company Profiles

10.1.1 Overview10.1.2 Financial Performance10.1.3 Product Outlook10.1.4 Key Developments

11 Appendix

11.1 Related Research

Request Report Customization @ https://www.marketresearchintellect.com/product/global-complementary-and-alternative-medicine-market-size-forecast/?utm_source=WN&utm_medium=888

About Us:

Market Research Intellect provides syndicated and customized research reports to clients from various industries and organizations with the aim of delivering functional expertise. We provide reports for all industries including Energy, Technology, Manufacturing and Construction, Chemicals and Materials, Food and Beverage and more. These reports deliver an in-depth study of the market with industry analysis, market value for regions and countries and trends that are pertinent to the industry.

Contact Us:

Mr. Steven FernandesMarket Research IntellectNew Jersey ( USA )Tel: +1-650-781-4080

Email: [emailprotected]

TAGS: Complementary And Alternative Medicine Market Size, Complementary And Alternative Medicine Market Growth, Complementary And Alternative Medicine Market Forecast, Complementary And Alternative Medicine Market Analysis, Complementary And Alternative Medicine Market Trends, Complementary And Alternative Medicine Market

See the original post:

Complementary And Alternative Medicine Market Emerging Trends, Opportunity, Industry Overview and Growth Analysis Forecast To 2026 - 3rd Watch News

Post Views: 687

In the past couple of years, vaping has seemed to emerge everywhere, particularly concentrated in college-aged populations. On the other side of the health spectrum, there has also seemed to be a rise in alternative medicine essential oils being one of the many options for natural wellness.

The two phenomena have been combined into whats called a personal diffuser, or a device that allows vaporizing essential oils of your choice to become possible.

Vaping is the inhalation and exhalation of vapor from either a vape pen or e-cigarette, devices that are typically defined as electronic nicotine delivery systems (ENDs). Yet, not all vaping necessarily involves nicotine weed vape pens, CBD vape pens and now essential oil vape pens are becoming more and more common.

Essential oil/aromatherapy vape pens are typically labeled as diffuser sticks or personal diffusers. These devices combine essential oils, water and vegetable glycerin to create a cloud of vapor when exhaled. On the MONQ website, they claim that when using one of their personal diffusers, one should not inhale the vapor into their lungs as that will lower the effectiveness of the aromatherapy experience.

Essential oils are compounds extracted from different plants, such as lavender, peppermint, tea tree or eucalyptus, for various healing purposes. The extraction methods for getting these compounds vary based on what plant is being used. Some more common methods include steam distillation, cold-press extraction or water distillation.

To receive the benefits of essential oils, people typically apply them to their skin or inhale them via a diffuser. When an essential oil such as tea tree or lavender oil is applied topically, to heal an ache or pain or for cosmetic purposes, the compounds from the oil absorb into the skin and eventually into the bloodstream.

People who vaporize essential oils and inhale them via a diffuser are usually seeking out the psychological benefits of the compound. When an essential oil is inhaled, it enters into our respiratory systems, creating a potential psychological response via association. This is why many people believe that the results of essential oils are subjective, as different smells mean different things to all of us and can thus ignite various emotional responses.

Although essential oils have been used for health purposes for centuries, theres still very little conclusive research published about their benefits.

Each plant that essential oils are derived from will be unique, which are dependent on several environmental factors, such as the weather and geographical location. Unlike a synthetically produced prescription or pharmaceutical drug, essential oils will contain different chemistry each time they are produced. Because of this, essential oils cannot be standardized, which blocks any potential research on their effectiveness.

When studying the benefits of essential oils, it can be difficult to determine what causes the advantages that they may or may not be giving off. For example, when lavender oil is applied with a massage, it is hard to decipher whether the oil or massage itself is producing the desired effects of stress relief.

Stemming from the small amount of research about essential oils themselves, studies on the effectiveness of personal diffuser methods of essential oils are pretty much non-existent.

Despite all this inconclusive research, essential oils are still believed to be effective by a third of American adults, one poll found. And the oils havent proven to be completely useless. Lavender oil, for example, has been linked with improved sleep. Its also worth arguing for the placebo effect here if you feel better, calmer or healthier when youre using essential oils, then theres relatively no harm done.

Like any method of healing, alternative or otherwise, essential oils come with their own set of minor to major risks. As with vaping, some people with asthma may have a reaction to inhaling the diffused aroma of essential oils. Many people have also reported experiencing allergic reactions when using essential oil products.

Again, because theres not much conclusive research on the practices of essential oils, and the practices of vaping, theres also not much out there about the safety of vaporizing essential oils via a personal diffuser. The MONQ websites safety page cautions against anyone 18 or under using their products. They warn their users about the hand-to-mouth habits associated with personal diffusers, as that may lead to the negative habit of smoking or vaping nicotine.

If you choose to participate in vaporizing essential oils, its best to research as much as possible about the safety practices behind what product you are using. Whether its a faulty fad or a beneficial practice that has not yet been determined, always do what is best for your mind and body.

Read more from the original source:

The Newest Alternative Health Fad: Vaping Essential Oils - Study Breaks

WEDNESDAY, March 4, 2020 (HealthDay News) -- E-cigarettes were initially thought to be a safer alternative to traditional cigarettes, but a recent outbreak of serious lung illnesses and deaths linked to the nicotine delivery devices called that belief into question.

Now, a new case report details another type of lung illness in a 15-year-old girl who regularly used e-cigarettes: necrotizing pneumonia.

Necrotizing pneumonia is an uncommon complication of pneumonia. It destroys areas of lung tissue, and can occur even if someone has been treated with antibiotics, according to a previous review in Biomed Central.

"It's pretty unusual for a generally healthy person to get an invasive pneumonia like this, but not impossible," said Dr. Ravi Kalhan, a professor of medicine and preventive medicine in the division of pulmonary and critical care medicine at Northwestern Feinberg School of Medicine in Chicago. Kalhan was not involved in the current case, but is familiar with the new report.

He said experts can't know for sure if vaping caused this particular illness, but animal studies have suggested impaired immune defenses in the lungs.

"The idea that in this case vaping created a setup for severe pneumonia in an individual is a reasonable hypothesis, but a single case does not prove it," Kalhan said.

What is already known, however, is that more than 2,800 people across all 50 states have been hospitalized with life-threatening respiratory dysfunction tied to recent e-cigarette use, according to the U.S. Centers for Disease Control and Prevention. Sixty-eight of those patients died.

Research strongly suggests that an additive called vitamin E acetate, sometimes used in pot-laced vapes, may be triggering these illnesses.

But health experts have also raised a more general alarm about soaring rates of e-cigarette use among teens. A CDC report from November reported that about 1 in every 5 high school students had used e-cigarettes within the past month.

The new case report, written by Dr. Joseph Domachowske and colleagues from Upstate Medical University, State University of New York in Syracuse, revealed that the teen patient had a habit of daily nicotine vaping. She used e-cigarettes several times each hour, and had done so for the past nine months. Like many people who use e-cigarettes, the girl used flavored nicotine, including apple, mango, cotton candy and birthday cake flavors.

She said she used both disposable and refillable penlike vape devices. She said she hadn't altered the devices in any way. The girl admitted to occasionally smoking marijuana, but not with an e-cigarette.

In September 2019, she went to the hospital complaining of difficulty breathing. She had been sick for about a week prior.

Imaging of her lungs showed that lung tissue damage had occurred.

Luckily, she responded well to treatment and was released after more than a week in the hospital, including six days in the ICU.

But she has yet to fully recover. Before this report, the doctors had seen the teen one month after she completed a three-week course of antibiotics. She still couldn't climb more than a flight of stairs without getting out of breath. She also couldn't walk quickly from one class to another without getting winded.

Dr. Len Horovitz, a pulmonary specialist at Lenox Hill Hospital in New York City, was not part of the study, but said this appeared to be "yet another horror story of vaping."

He added that this unusual case seems to represent a previously undescribed cause of vaping-related pneumonia.

Kalhan said that this report, published March 4 in the journal Pediatrics, and the many previous lung injury cases, suggest one thing.

"I think it's clear that vaping is definitely not good for you," he said.

"Inhaling anything but air is a risky behavior. We don't know at all what the true short- and long-term effects are of vaping, and speculation that it's safe [or safer than cigarettes] is just that -- speculation. The effects have not been carefully studied and need to be. In the meantime, I'd just remind people that the lungs were designed to inhale AIR, and that's it. Not anything else," Kalhan advised.

More information

Learn more about vaping-related lung injuries from the U.S. Centers for Disease Control and Prevention.

SOURCES: Ravi Kalhan, M.D., M.S., professor, medicine and preventive medicine, and director, Asthma and COPD program, division of pulmonary and critical care medicine, Northwestern Feinberg School of Medicine, Chicago; Len Horovitz, M.D., pulmonary specialist, Lenox Hill Hospital, New York City; March 4, 2020, Pediatrics

Excerpt from:

'Necrotizing Pneumonia' May Be New Vaping Hazard - HealthDay

With 7.5 per cent of Indias population afflicted by some kind of mental health disorder,the country faces a huge burden of mental illnesses. Can leveraging the benefits of alternativetraditional therapies along with modern medicine-based treatments help achievebetter mental health for the masses? Health experts today are discussingand debating this question.

When used individually, or as adjuvant therapies alongside mainstream treatments, a numberof alternative practices can help people achieve better mental health and wellness. Astudy published in the BMC Complementary and Alternative Medicine journal concludedthat yoga, mindfulness-based cognitive therapy and cognitive behavioural therapy wereeffective in promoting overall mental health. Similarly, a study published intheJournal of Evidence-BasedIntegrative Medicinefound that anhour-long soundmeditation session helped people reduce tension,anger, fatigue,anxiety,anddepressionwhile increasing a sense of spiritual well-being.Here are some therapies that can help:

Sound healing

Sound healing or music therapy is an ancient knowledge that has been used forcenturies as a healing tool. The use of music, singing, and instruments that releasevibrations to improve the mental, emotional and physical state of a person is a practicethat can effectively be termed as vibrational medicine.

Sound healing creates a shift inthe brainwave state allowing the mind to go from the normal beta state (normal wakingconsciousness) to the alpha state (relaxed consciousness), quite similar to meditation.Sound healing particularly helps in conditions like anxiety, stress, depression and sleepdisorders.

Mindfulness meditation

Sages and saints spent years meditating onthe truth of the self and achieved a higher mental and spiritual elevation through theprocess. Mindfulness meditation is a process that trains the mind to focus on thepresent, moment by moment, breath by breath. Rooted in Buddhism, it involves using breathing techniques and generating completeawareness of the mind and body by becoming highly aware of the present. People who learn the art are said to be calmer, clearer and less stressed in their daily lives.

Yoga

Yoga helps achieve a peacefulalignment between the body and mind. It modulates the stress response systems bytraining the mind to perceive stress and anxiety differently. It not only relieves symptoms of stress and anxiety, but also helps curtail thenegative impact of stress on the body and reduces risk factors for chronic diseases, suchas heart disease and high blood pressure.

A study published in the journalFrontiers inPsychiatry found that yoga had positive effects on people with mild depression and sleep problems. It also improved symptoms of psychiatric disorders like schizophreniaand ADHD among patients using medication.

(The author is director Poddar Wellness Ltd)

See original here:

Break the stigma through therapy - Deccan Herald

Effect of Each Drug Treatment on Respiratory Drive as Measured by Minute Ventilation LS Mean Difference from Placebo at Emax

Effect of Each Drug Treatment on Respiratory Drive as Measured by Minute Ventilation LS Mean Difference from Placebo at Emax

BELBUCA Effect on Respiratory Drive was Comparable to Placebo in Clinical Trial at all Tested Doses

Immediate Release Oral Oxycodone HCl Associated with a Dose-Dependent Decrease in Respiratory Drive Compared to Placebo

RALEIGH, N.C., Feb. 27, 2020 (GLOBE NEWSWIRE) -- BioDelivery Sciences International, Inc. (NASDAQ: BDSI), a rapidly growing specialty pharmaceutical company dedicated to patients living with serious and complex chronic conditions, today presented at the American Academy of Pain Medicines (AAPM) 36th Annual Meeting the results of a study titled, A Phase I Placebo-Controlled Trial Comparing the Effect of Buprenorphine Buccal Film and Oral Oxycodone Hydrochloride on Respiratory Drive.

In May 2019, in response to significant challenges chronic pain patients face in obtaining adequate care and the ongoing opioid crisis, The Pain Management Best Practices Inter-Agency Task Force report recommended more research activities directed to better understanding the use of buprenorphine, a Schedule III opioid. Opioids can cause serious, life-threatening, or fatal respiratory depression. Respiratory depression is a breathing disorder characterized by slow and ineffective breathing and is the leading cause of opioid related deaths. In this clinical trial, BDSI evaluated the effect of BELBUCA (buprenorphine buccal film), a Schedule III opioid, and oral oxycodone HCI, a Schedule II opioid, on respiratory drive.

Study Design: Study subjects (N = 19) were healthy males and females self-identifying as recreational drug users and determined via naloxone challenge to not be physically dependent on opioids.

Effect on respiratory drive was assessed using a double-blind, double-dummy, 6-treatment, 6-period, placebo controlled, randomized crossover design.

Treatments studied included single doses of: BELBUCA (300 mcg, 600 mcg, and 900 mcg); oral oxycodone hydrochloride (Oxy 30 mg and 60 mg); and placebo (each separated by a 7-day washout period).

Respiratory drive was evaluated by measuring the ventilatory response to hypercapnia (excess carbon dioxide in the bloodstream) through assessment of the maximum change in minute ventilation (Emax), which is the maximum amount inhaled or exhaled in one minute, after administration of each study drug. Statistical analyses were performed using a linear mixed-effects model.

Results: The least square mean differences in Emax versus placebo were as follows: Oxy 30 mg (828.5, P=0.668); Oxy 60 mg (5188.6, P=0.008); BELBUCA 300 mcg (+1206.9, P=0.533); BELBUCA 600 mcg (+245.4, P=0.896); and BELBUCA 900 mcg (+1473.3, P=0.440).

A chart/graphic accompanying this announcement is available at:https://www.globenewswire.com/NewsRoom/AttachmentNg/d148dcf8-f359-4b36-ada6-dd34da39f6e6

Conclusion: BELBUCA effect on respiratory drive was comparable to placebo at all doses tested.

The effect of immediate release oral oxycodone HCl resulted in a dose-dependent decrease in respiratory drive compared to placebo.

This is an important and novel study that shows the comparative effects of buprenorphine buccal film and oral oxycodone on respiratory drive, stated Lynn Webster, M.D., the principal investigator of the study. Thomas Smith, M.D., Chief Medical Officer at BDSI, added, Consistent with the Task Forces recommendation, BDSI is providing the medical community with the results of this safety study to help providers make informed treatment decisions. This study provides additional scientific support for the use of BELBUCA as a primary treatment option for the management of pain severe enough to require daily, around-the-clock, long-term opioid treatment and for which alternative treatment options are inadequate.

Serious, life-threatening, or fatal respiratory depression may occur with use of BELBUCA. BELBUCA is contraindicated in patients with significant respiratory depression; acute or severe bronchial asthma in an unmonitored setting or in the absence of resuscitative equipment; known or suspected gastrointestinal obstruction, including paralytic ileus; and hypersensitivity (e.g., anaphylaxis) to buprenorphine.

Please see important safety information about BELBUCA below.

For full Prescribing Information, including Boxed Warning, visit http://www.belbuca.com.

The Pain Management Best Practices Inter-Agency Task Force report is available for viewing online at https://www.hhs.gov/ash/advisory-committees/pain/index.html.

IMPORTANT SAFETY INFORMATION ABOUT BELBUCA

INDICATIONBELBUCA (buprenorphine buccal film) is indicated for the management of pain severe enough to require daily, around-the-clock, long-term opioid treatment and for which alternative treatment options are inadequate.

Limitations of Use

IMPORTANT SAFETY INFORMATION about BELBUCA

Addiction, Abuse, and Misuse

BELBUCA exposes patients and other users to the risks of opioid addiction, abuse, and misuse, which can lead to overdose and death. Assess each patients risk prior to prescribing BELBUCA, and monitor regularly for these behaviors and conditions.

Risk Evaluation and Mitigation Strategy (REMS)

To ensure that the benefits of opioid analgesics outweigh the risks of addiction, abuse, and misuse, the FDA has required a REMS for these products. Under the requirements of the REMS, drug companies with approved opioid analgesic products must make REMS-compliant education programs available to healthcare providers. Healthcare providers are strongly encouraged to

Serious, life-threatening, or fatal respiratory depression may occur with use of BELBUCA. Monitor for respiratory depression, especially during initiation of BELBUCA or following a dose increase. Misuse or abuse of BELBUCA by chewing, swallowing, snorting, or injecting buprenorphine extracted from the buccal film will result in the uncontrolled delivery of buprenorphine and poses a significant risk of overdose and death.

Accidental Exposure

Accidental exposure to even one dose of BELBUCA, especially in children, can result in a fatal overdose of buprenorphine.

Neonatal Opioid Withdrawal Syndrome

Prolonged use of BELBUCA during pregnancy can result in neonatal opioid withdrawal syndrome, which may be life-threatening if not recognized and treated. If prolonged opioid use is required in a pregnant woman, advise the patient of the risk of neonatal opioid withdrawal syndrome and ensure that appropriate treatment will be available.

Risks from Concomitant Use with Benzodiazepines Or Other CNS Depressants

Concomitant use of opioids with benzodiazepines or other central nervous system (CNS) depressants, including alcohol, may result in profound sedation, respiratory depression, coma, and death. Reserve concomitant prescribing for use in patients for whom alternative treatment options are inadequate; limit dosages and durations to the minimum required; and follow patients for signs and symptoms of respiratory depression and sedation.

CONTRAINDICATIONS

BELBUCA is contraindicated in patients with significant respiratory depression; acute or severe bronchial asthma in an unmonitored setting or in the absence of resuscitative equipment; known or suspected gastrointestinal obstruction, including paralytic ileus; and hypersensitivity (e.g., anaphylaxis) to buprenorphine.

WARNINGS AND PRECAUTIONS

Addiction, Abuse, and Misuse

Opioid Analgesic Risk Evaluation and Mitigation Strategy (REMS)

Life-Threatening Respiratory Depression

Neonatal Opioid Withdrawal Syndrome

Risks due to Interactions with Benzodiazepines or Other Central Nervous System Depressants

If the decision is made to prescribe a benzodiazepine or other CNS depressant concomitantly with an opioid analgesic, prescribe the lowest effective dosages and minimum durations of concomitant use. Follow patients closely for signs and symptoms of respiratory depression and sedation.

Risk of Life-Threatening Respiratory Depression in Patients with Chronic Pulmonary Disease or in Elderly, Cachectic, or Debilitated Patients

Adrenal Insufficiency

QTc Prolongation

Severe Hypotension

Risks of Use in Patients with Increased Intracranial Pressure, Brain Tumors, Head Injury, or Impaired Consciousness

Hepatotoxicity

Risk of Overdose in Patients with Moderate or Severe Hepatic Impairment

Anaphylactic/Allergic Reactions

Withdrawal

Risk of Use in Patients with Gastrointestinal Conditions

Increased Risk of Seizures in Patients with Seizure Disorders

Risks of Use in Cancer Patients with Oral Mucositis

Risks of Driving and Operating Machinery

ADVERSE REACTIONS

Please see full Prescribing Information, including Boxed Warning and Medication Guide, for BELBUCA.

To report SUSPECTED ADVERSE REACTIONS, contact BioDelivery Sciences International, Inc. at 1-800-469-0261 or FDA at 1-800-FDA-1088 or http://www.fda.gov/safety/medwatch.

Intended for healthcare professionals of the United States of America only.

About BioDelivery Sciences International, Inc.BioDelivery Sciences International, Inc. (NASDAQ: BDSI) is a commercial-stage specialty pharmaceutical company dedicated to patients living with chronic conditions. BDSI has built a portfolio of products that includes utilizing its novel and proprietary BioErodible MucoAdhesive (BEMA) technology to develop and commercialize, either on its own or in partnership with third parties, new applications of proven therapies aimed at addressing important unmet medical needs. BDSI's marketed products address serious and debilitating conditions, including chronic pain, opioid dependence, and opioid-induced constipation.

Cautionary Note on Forward-Looking StatementsThis press release and any statements of employees, representatives, and partners of BDSI related thereto contain, or may contain, among other things, certain forward-looking statements within the meaning of the Private Securities Litigation Reform Act of 1995. Such forward-looking statements involve significant risks and uncertainties. Such statements may include, without limitation, statements with respect to the BDSIs plans, objectives, projections, expectations and intentions and other statements identified by words such as projects, may, will, could, would, should, believes, expects, anticipates, estimates, intends, plans, potential or similar expressions. These statements are based upon the current beliefs and expectations of the BDSIs management and are subject to significant risks and uncertainties, including those detailed in the BDSIs filings with the Securities and Exchange Commission. Actual results may differ materially from those set forth or implied in the forward-looking statements. These forward-looking statements involve certain risks and uncertainties that are subject to change based on various factors (many of which are beyond the BDSIs control) including those set forth in our 2018 annual report on Form 10-K filed with the US Securities and Exchange Commission and subsequent filings. BDSI undertakes no obligation to publicly update any forward-looking statements, whether as a result of new information, future presentations or otherwise, except as required by applicable law.

2020 BioDelivery Sciences International, Inc. All rights reserved.

Contact:Tirth T. PatelDirector of Investor Relations[emailprotected](919) 582-0294

Follow this link:

BioDelivery Sciences Announces Phase I Clinical Trial Results at the American Academy of Pain Medicine's 36th Annual Meeting - GuruFocus.com