The increase in the Severe Asthma market size is a direct consequence of the expected launch of potential therapies an increase in the diagnosed prevalent population of Severe Asthma and increasing demand for personalized therapies.
LAS VEGAS, June 8, 2022 /PRNewswire/ -- DelveInsight's Severe Asthma Market Insightsreport proffers a detailed comprehension of Severe Asthma market size by treatment, epidemiology, emerging therapies, market share of the individual therapies, current and forecasted Severe Asthma market size from 2019 to 2032 segmented into 7MM (the USA, EU5 (the UK, Italy, Spain, France, and Germany), and Japan).
Some of the salient features from the Severe Asthma Market Report:
For further information on market impact by therapies, download the Severe Asthmamarket sample @ Severe Asthma Therapeutics Market Scenario
Severe Asthma Overview
Asthma is the most common chronic respiratory disease all over the globe. It affects the airways in the lungs, which become inflamed and narrowed due to various triggers, making it harder for air to flow out. It is a complex activity between airway inflammation and airway remodelling that results in airway hyper-responsiveness (AHR), which further leads to variable and excessive airway contraction. The characteristic Asthma symptoms include wheezing, shortness of breath, cough, a sensation of tightness in the chest, straining of neck and chest muscles, rapid breathing, and changes in heart rate.
Asthma classification can be broadly done into intermittent or persistent. Here, Persistent asthma is further sub-divided based on severity into mild, moderate, and severe. Severe Asthma occurs due to various genetic, environmental, and psychological factors as well as respiratory infections. Severe Asthma symptoms appear often in the nighttime with a persistent airflow obstruction with a forced expiratory volume (FEV1) of less than 60% predicted before treatment.
Based upon response to treatment, Severe Asthma is further classified into type-2 inflammation and non-type-2 inflammation. Type-2 inflammation includes allergic asthma and eosinophilic asthma (or e-asthma) while non-type-2 inflammation includes non-eosinophilic asthma.
Severe Asthma Epidemiology Segmentation
As per the assessment of DelveInsight, the total diagnosed prevalent (adult + pediatric) cases of Asthma in the 7MM was observed to be approximately 54 million cases in 2021. These cases are expected to increase by 2032.
As per DelveInsight's estimates, among 7MM, the United States had the highest diagnosed cases of adult Asthma with almost 20 million cases in 2021.
The Severe Asthma Market report proffers epidemiological analysis for the study period 2019-2032 in the 7MM segmented into
Learn more about the Severe Asthma Population Trends for the 7 MM by downloading@ Severe AsthmaEpidemiology Forecast Report
Severe Asthma Market Outlook
The fundamental goal of Asthma therapy is to minimize airway inflammation and also reduce the Asthma symptoms that come with it. To limit the likelihood of exacerbation, guidelines-based care focuses on illness severity and selecting the right medicinal therapy. Inhaled corticosteroids are the most common chronic asthma treatment, but quick-relief (reliever) or rescue medications are frequently used to reduce acute Asthma symptoms. Short-acting beta-agonists (SABAs) relieve airway bronchoconstriction quickly and are indicated as a symptom-relieving rescue drug. If asthma still isn't under control, long-acting beta 2 agonists (LABA), montelukast, or theophylline are added. If Asthma symptoms and flare-ups persist, oral corticosteroids are prescribed.
There are currently six US FDA approved monoclonal antibodies for add-on biological Severe Asthma treatment. They include Cinqair (reslizumab) Teva Pharmaceutical, Dupixent (dupilumab) Sanofi, and Regeneron, Fasenra (benralizumab) AstraZeneca/Kyowa Kirin, Tezspire (tezepelumab) AstraZeneca and Amgen, Nucala (mepolizumab) GlaxoSmithKline, and Xolair (omalizumab) Novartis/Genentech.
Several new severe asthma therapeutic options are currently being developed. The key assets include GSK3511294 (Depemokimab) by GlaxoSmithKline, PT010 (Breztri/Trixeo/BGF MDI (budesonide-glycopyrrolate-formoterol inhalation)) by AstraZeneca, and PT027 (BDA MDI/Budesonide/albuterol sulfate metered-dose inhaler) by AstraZeneca and Bond Avillion. They are in the late stage of development and are expected to launch in the forecasted period (2022-2032). Several other companies are also developing drugs for Severe Asthma treatment including Novartis (CSJ117), 4D pharma (MRx-4DP0004), Roche (RG6173), Pieris Pharma, and AstraZeneca (PRS-060/AZD1402), Biosion (BSI-045B), among others.
Discover more about therapy set to grab substantial Severe Asthmamarket share @ Severe Asthma Market Landscape
Severe AsthmaPipeline Therapies and Key Companies
To know about more pipeline therapies covered in the report, visit @ Severe AsthmaPipeline Analysis, Clinical Trials, and Emerging Therapies
Severe AsthmaMarket Dynamics
Severe Asthma market growth in the coming years is dependent on several factors such as an increase in the diagnosed prevalent population of Severe Asthma and increasing demand for personalized therapies. Also, the development of well-designed, randomized, controlled non-crossover trials with the potential benefits for patients will drive the Severe Asthma market growth in the forecast period. In addition to that, approvals and entry of new drugs will change the Severe Asthma market dynamics in the future. Several pharmaceutical giants are investigating drugs for Severe Asthma treatment with an improved diagnostic approach leading to a rise in the Severe Asthma market in the coming years.
On the other hand, a lack of effective specific treatments in non-eosinophilic asthma (NEA) can represent an orphan asthma endotype serving as a drawback in the Severe Asthma market growth. Other factors such as a high cost of treatment, limitations in diagnosis, incorrect inhaler techniques, and poor adherence to treatment can all be considered as potential barriers to the rise of the Severe Asthma market.
Know which therapy is expected to score the touchdown first @ Severe Asthma Market Landscape and Forecast
Scope of the Severe Asthma Market Report
Request for a Webex demo of the report @ Severe Asthma Therapeutics Market
Table of Contents
1
Key Insights
2
Report Introduction
3
Severe Asthma Market Overview at a Glance
4
Executive Summary of Severe Asthma
5
Severe Asthma Epidemiology and Market Methodology
6
Severe Asthma: Disease Background and Overview
7
Diagnosis of Severe Asthma
8
Severe Asthma Treatment
9
Conclusion for Severe Asthma
10
Severe Asthma Epidemiology and Patient Population
11
Severe Asthma Patient Journey
12
Key Endpoints in Severe Asthma Clinical Trials
13
Severe Asthma Marketed Therapies
14
Severe Asthma Emerging Therapies
15
Severe Asthma: 7 Major Market Analysis
16
Market Access and Reimbursement
17
KOL Views
18
Severe Asthma Market Drivers
19
Severe Asthma Market Barriers
20
Severe Asthma SWOT Analysis
21
Severe Asthma Unmet Needs
22
Appendix
23
DelveInsight Capabilities
24
Disclaimer
25
About DelveInsight
Get in touch with our Business executive @Severe Asthma Market Landscape Analysis
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Severe Asthma Market to Progress Upto USD 7 Billion by 2032 | DelveInsight - PR Newswire
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