Category Archives: Food Supplements

Many people are familiar with probiotics, the live microorganisms known to improve gut health. Probiotics are naturally found in some foods like yogurt, sauerkraut, and kimchi and are also commonly taken in supplement form to help support the digestive system.

But what about prebiotics?

Even though prebiotics affect the health of your digestive system as well as many other parts of the body these nutrients are often overlooked.

This article tells you everything you need to know about prebiotics, including what they are, how they affect your health, and how to take prebiotic supplements.

Gut microbiota refers to the trillions of microorganisms that live in your gastrointestinal (GI) tract and make up your gut microbiome. Your large intestine is home to the majority of these microorganisms (1).

They carry out functions that are essential to overall health, including nutrient metabolism and regulation of the immune system (2).

Your gut microbiota can even influence disease risk, including the risk of developing colon cancer, inflammatory bowel disease, and type 2 diabetes (3).

Diet and lifestyle factors significantly impact the diversity and types of microorganisms that live in the GI tract (2).

Prebiotics are essential to a healthy microbiome. In simple terms, theyre nutrients that get broken down by gut bacteria.

Bacteria in the large intestine ferment prebiotics. This releases byproducts called short-chain fatty acids. These byproducts act as energy sources for the cells lining the colon, called colonocytes, and benefit health in many other ways (1).

Prebiotics also influence the makeup and function of gut bacteria, promoting the growth of beneficial microbes.

According to the International Scientific Association of Probiotics and Prebiotics, in order for a compound to be classified as a prebiotic, it should (1):

There are many different types of prebiotics, including (1):

Most prebiotics are considered carbohydrates. However, some prebiotics are not classified as carbohydrates. Cocoa flavonols are an example of non-carbohydrate oligosaccharides.

Although prebiotics are often confused with probiotics, they are not the same. Probiotics are live microorganisms found in your gut, certain foods, and supplements that benefit health when taken in certain amounts.

On the other hand, prebiotics are nutrients that are dietary compounds that stimulate the growth and activity of certain microorganisms (4).

Some experts have referred to prebiotics as microbiome fertilizers (5).

Read more about the differences between prebiotics and probiotics here.

Prebiotics exist naturally in some foods, including (1, 6):

There arent a lot of foods that naturally contain prebiotics. Plus, many foods that are high in prebiotics, such as artichokes and beans, arent a regular part of many folks diets.

For this reason, synthetic prebiotics are added to some foods to improve their nutritional content and health value. Prebiotics are also made into dietary supplements like powders and capsules.

Prebiotic supplements are used to treat specific health conditions and to improve overall gut health.

Some studies have shown that supplementing your diet with prebiotics may benefit people with gut-related conditions, high blood sugar, and more (7, 8).

However, compared with probiotics, research investigating the health effects of prebiotic supplements is much more limited.

Prebiotics are essential to a healthy microbiome. Prebiotics act as a fertilizer to the microbiome, as they stimulate the growth and activity of certain microorganisms.

A diet rich in prebiotics promotes digestive system health by stimulating the growth of beneficial microorganisms.

The fermentation of prebiotics produces short-chain fatty acids (SCFAs), including acetate, propionate, and butyrate. They play important roles in gut and metabolic health.

For example, SCFAs provide energy for colonocytes and are involved in mucus production, regulation of intestinal pH, and more.

In addition to gut health, prebiotics influence immune function, blood sugar regulation, appetite, and energy expenditure (9, 10).

Studies suggest that when taken in specific amounts, prebiotics may improve health in various ways.

Because prebiotics stimulate the growth of beneficial bacteria and improve certain aspects of gut health, they may benefit those who have gut-related health conditions like constipation.

A 2020 review noted that treatment with inulin, a type of prebiotic, may benefit folks who have irritable bowel syndrome (IBS) with constipation (11).

It may improve the frequency and consistency of stool as well as intestinal transit time, or the time it takes food to move through the digestive tract (11).

However, a 2021 review found limited evidence that treatment with prebiotics or prebiotics mixed with probiotics (synbiotics) is helpful for treating IBS and that the quality of existing studies is low (12).

So, most experts, including the American College of Gastroenterology, dont recommend prebiotics as a treatment for IBS.

Another 2020 review that included 21 randomized controlled trials found that prebiotic treatments were effective for improving stool consistency, number of bowel movements, and bloating in people with chronic constipation.

However, the researchers noted that its still unclear which prebiotic formulation is best for treating constipation (13).

Even though more research is needed to assess the effectiveness of prebiotic supplements on constipation and IBS, consuming a diet rich in foods high in prebiotics supports overall gut health and may help stimulate the growth of beneficial microorganisms.

Eating a diet rich in prebiotics and taking prebiotic supplements may benefit certain aspects of metabolic health, including blood sugar, cholesterol, and triglyceride levels.

A 2019 review of 33 studies found that treatment with the prebiotics called Inulin-type fructans (ITF) significantly reduced fasting blood sugar, a long-term blood sugar control marker called glycosylated hemoglobin (HbA1c), and fasting insulin levels (14).

The researchers found that these results were most significant in people with prediabetes and type 2 diabetes and recommended that people with these conditions supplement with 10 grams of ITF per day for 6 weeks and longer to reap these potential benefits (14).

Additionally, a 2021 review of 33 randomized controlled human trials found that ITF supplements significantly reduced levels of blood sugar, total cholesterol, and triglycerides in people with prediabetes and diabetes (15).

However, not all studies of prebiotics in these populations have found benefits.

A small 2021 randomized, double-blind crossover trial including 29 people with type 2 diabetes found that treatment with 16 grams of ITF daily for 6 weeks had no effect on fasting or post-meal blood sugar levels compared with a control treatment (16).

While prebiotic supplements may help improve certain aspects of metabolic health in people with prediabetes and type 2 diabetes, more research is needed to confirm these potential benefits.

In addition to having possible benefits for metabolic health and the potential to improve certain digestive conditions, prebiotics may benefit health in the following ways.

Keep in mind that this list is not exhaustive, and there are many other potential benefits related to prebiotics.

Clinical trials exploring the effects of prebiotic supplements on knee osteoarthritis, obesity, allergies, multiple sclerosis, type 1 diabetes, atopic dermatitis, and more are currently underway (22, 23).

Prebiotics may help improve constipation, blood sugar levels, inflammatory markers, and more. However, more research is needed to confirm these potential benefits.

Most types of prebiotics are considered safe and arent associated with serious side effects (24).

Prebiotics are even considered safe during pregnancy and lactation (25).

However, because prebiotics are fermented in the large intestine, taking large doses may lead to symptoms like gas, cramps, diarrhea, and bloating.

The likelihood of a prebiotic causing the side effects listed above depends on several factors.

Prebiotics with a shorter molecular structure or chain length, such as inulin, are more rapidly fermented in the first part of the colon, while prebiotics with longer chain lengths are fermented at a slower rate in the latter part of the colon.

So, shorter-chain prebiotics are more likely to cause GI side effects (24).

Whats more, larger doses of prebiotics are more likely to cause certain side effects than smaller doses.

While low doses of 2.510 grams per day can lead to mild symptoms like gas, high doses of 4050 grams per day could cause diarrhea (24).

Its important to note that a daily dose of 2.510 grams of prebiotics is necessary in order to reap their health benefits. That means prebiotics may cause side effects, even at recommended therapeutic doses (1).

Although prebiotics havent been associated with dangerous side effects, it doesnt mean theyre the right choice for everyone. While some people may have no side effects after they take prebiotics, some may experience significant bloating and GI discomfort.

If youre interested in taking prebiotics, its best to get advice from a knowledgeable healthcare professional first. They can help you decide whether prebiotics are appropriate for your health needs.

Prebiotics are considered safe but may cause GI side effects in some people, including bloating, cramping, and diarrhea.

Experts suggest that if you want to take prebiotics, a daily dose of 2.510 grams is the minimum required for a meaningful effect on your health.

The majority of prebiotic supplements on the market contain between 1.55 grams of prebiotics per serving (1).

Most prebiotic supplement manufacturers recommend taking a serving of prebiotics one or more times per day with a food or beverage.

Prebiotic powders can be mixed with beverages like water or smoothies.

They can also be added to foods like yogurt.

Keep in mind that some prebiotics have special instructions for use.

For example, psyllium husk, a fiber with prebiotic properties, should be taken with plenty of fluids, as it has a bulking effect on stools. It can lead to constipation and even intestinal or esophageal obstruction if its not taken with adequate fluids (26).

If youre trying out a new prebiotic supplement, its important to read instructions and use the prebiotic as recommended to avoid potential side effects.

Also, its suggested to start with a smaller dose of prebiotics and slowly increase the amount over time in order to minimize digestive side effects.

The majority of prebiotic supplements on the market contain between 1.55 grams of prebiotics per serving. They can be taken with food or beverages. Be sure to follow the supplement instructions to avoid potential side effects.

Prebiotics are sometimes referred to as microbiome fertilizers.

They promote the growth of beneficial microbes, fuel colonocytes, and influence health in many other ways.

Some evidence suggests that prebiotic supplements may be helpful for those with chronic constipation, prediabetes, type 2 diabetes, and more but more research is needed.

If youre interested in taking a prebiotic supplement, talk with a healthcare professional first. They can help you decide whether a prebiotic supplement is right for you.

Originally posted here:

What Are Prebiotics? Prebiotics Benefits, Foods, and Downsides - Healthline

Pancreatic ductal adenocarcinoma (PDA) is one of the deadliest human cancers with no clinically effective treatment options. PDA is characterised by an intense fibroinflammatory stroma, poor vascularity, deregulated nutrient levels, and rich deposition of extracellular matrix (ECM) components. A pancreatic tumours microenvironment is highly stromal, meaning the mass itself is mostly comprised of connective tissue and non-cancerous immune cells. Hyaluronic acid or hyaluronan (HA) is a major stromal component and its accumulation has been shown to play a central role in promoting tumorigenesis and progression of disease.

Hyaluronic acid, or HA, is a known presence in pancreatic tumours, but a new study from researchers at theUniversity of Michigan Health Rogel Cancer Center shows that hyaluronic acid also acts as food to the cancer cells.

The findings were recently published ineLife and provide interesting insight into how pancreatic cancer cells grow indicating new possibilities to treat them.

Lead investigator Doctor Costas Lyssiotis and his study team looked at the metabolism of pancreatic cancer in preclinical models:how cells obtain nutrients and the spectrum of nutrients they utilize to fuel growth and enable therapeutic resistance.

READ MORE:Gloria Hunniford health: Presenter's diagnosis came as a 'huge shock'

Many people take hyaluronic acid supplements for its skin benefits, especiallyalleviating dry skin, reducing the appearance of fine lines and wrinkles and speeding up wound healing.

It can also help relieve joint pain in people with osteoarthritis.

Hyaluronic acid is a substance that occurs naturally in the skin, eyes, and joints.

Its primary function is to trap water inside tissue cells, keeping joints lubricated which according to the recent study could be the driving factor for increased pancreatic cancer tumours.

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Stroma occurs in the bodys natural scarring process, Lyssiotis explained.

As these scars are formed, an abundance of hyaluronic acid gets released.

Hyaluronic acida polymer or long chain of sugars attracts and retains water.

When a lot of it is present, pancreatic tumours become hyperdense, collapsing veins and blood flow.

Lyssiotis says these tumours then become very hard.

Its not that there arent veins or arteries inside the tumour. But the vasculature that is there cant withstand the extreme pressure.

Lyssiotis and his lab wanted to understand hyaluronic acid beyond its contribution to the physiological make-up of pancreatic cancer cells.

They considered the density of these tumours, and wondered: If cancer cells arent getting access to blood-derived nutrients, how are they getting the nutrients that fuel cell growth and become tumours?

Cells which make up a tumour are a combination of many different cell types, some malignant, some not.

A pancreatic tumours microenvironment is mostly comprised of connective tissue and non-cancerous immune cells.

The labs new work indicates that one-way cells do this is by scavenging the hyaluronic acid itself.

Hyaluronic acid doesnt only affect tumours by creating this density, which does make it difficult to treat, Lyssiotis said.

It is literally a chain of sugars. In retrospect, it makes good sense that the malignant cells are also feeding off hyaluronic acid.

Lyssiotis says this study demonstrates just how well pancreatic cancer cells scavenge nutrients in order to maintain their survival and growth.

Symptoms of pancreatic cancer include abdominal pain which radiates to the back, loss of appetite, jaundice, light-coloured stools, dark-coloured urine or itchy skin.

The rest is here:

Supplement warning: Popular pill taken for osteoarthritis acting as food to cancer cells' - Express

KANSAS CITY, MO. The United States will celebrate National Love Your Pet Day on Feb. 20, as if pet owners needed another reason to pamper their furry companions.

Steady growth in pet product sales over the last decade shows there is no shortage of love for todays dogs and cats. The continued humanization and premiumization of these products including pet food, treats and supplements is helping pet owners spoil their four-legged family members daily.

To join in the festivities, Pet Food Processing has highlighted eight pet nutrition products and announcements putting the human in humanization.

Maev Vitamin Bars

Maev, an emerging direct-to-consumer raw dog food brand, is reporting rapid month-over-month sales growth for its human-grade formulas and supplements. Aside from its raw dog foods and bone broth cubes, the company offers Vitamin Bars it describes as a dogs daily multivitamin.

"Maev Vitamin Bars are a daily supplement offering targeted, balanced nutrition to support your dogs functional goals, which map to the four most common health concerns in dogs in the United States: Anxiety & Mental Health, Weight & Digestion, Hip & Joint, and Coat & Skin, said Katie Spies, founder and chief executive officer of Maev. Many of Maevs customers like to mix and match Raw Food wellness goals with Vitamin Bar goals, to meet each dogs unique needs."

The Vitamin Bars look like something a pet owner could find in the natural health section of their local supermarket. They are formulated with peanut butter, shredded coconut flakes, chia seeds and functional ingredients based on the specific formula, all of which are human grade.

Come-pooch-a

In the final days of 2021, NutriSource Pet Foods introduced its first three meal topper products, all inspired by kombucha. A popular fermented drink touting probiotic and antioxidant benefits for humans, NutriSource has spun the fad into a line of liquid bone broth toppers formulated with postbiotics to support digestion and hydration in dogs.

Come-pooch-a makes mealtime a little more exciting while providing dogs with important nutrients that support their overall wellness, said Adam Martodam, marketing director at NutriSource.

CLIF Pet

In December 2021, Clif Bar & Company announced a new line of plant-based, jerky-style dog treats under its latest brand: CLIF Pet. Set to hit store shelves in early 2022, the line includes three formulas Sweet Potato & Blueberry Recipe, Pumpkin & Apple Recipe, and Butternut Squash & Cranberry Recipe each formulated with seven ingredients and promoting digestive health, according to the company.

Clif Bars flagship brands feature on-the-go snacks for active and health-conscious consumers. The companys expansion into the pet snack space reflects increased demand for function, humanization and convenience in the pet treat market.

To source ingredients for its new plant-based jerky for dogs, Clif Bars Chief Innovation Officer Rizal Hamdallah stated the company will be exploring integration with its existing ingredient supply chain as much as possible.

v-dog meatless jerky

While jerky isnt a novel sight in the pet treat market, the way some companies are formulating their jerky treats is. Roughly one year ago, v-dog introduced kindjerky, its first meatless jerky treats for dogs. Kindjerky treats are chewy and all natural, containing only animal-free ingredients like pea protein, sweet potato and non-GMO coconut glycerin.

"We're confident pet parents want clean, allergen-free options for their pups, said Darren Middlesworth, president at v-dog.

Vegan pet owners looking to pass on their food philosophies to dogs are seeing an increasing number of vegan dog food and treat products on the market today. V-dogs kindjerky adds to its portfolio of vegan dog food and dental chew products.

UnKibble

The human-grade trend continues with fresh, direct-to-consumer pet food brand Spot & Tango. The company launched UnKibble, a line of human-grade, fresh kibble alternative diets, in April 2020, and recently committed to establishing its first in-house production plant in Pennsylvania.

The ability to tailor formulations to each pets nutritional needs also speaks to the increasing humanization of this marketplace. For example, UnKibble diets can be customized based on a dogs age, weight, breed or activity level.

We created this brand because we wanted all pet parents to find comfort and confidence in what they were feeding their dogs, said Russell Breuer, founder and chief executive officer of Spot & Tango.

Goat milk for pets

Meyenberg, a producer of goat milk products for people, extended its consumer base to include puppies and kittens in early 2021. The company launched Tailspring, a brand of milk alternative products formulated to resemble the mothers milk. The 100% human-grade products are intended for nursing puppies and kittens and offer key vitamins, minerals and ingredients to support digestion.

At Meyenberg, weve been hearing from customers for decades how goat milk helped their animals to thrive sometimes even saving lives and we really wanted to serve the community of pets and their owners as well, said Kate Slaney, brand manager for Tailspring.

Staying hydrated

As pet owners become increasingly aware of the importance of keeping their dogs and cats hydrated, DoggyRade and KittyRade entered the market with isotonic beverages for pets that offer health benefits beyond hydration. Both products are designed to be low-calorie, energy-boosting and rehydrating solutions for dogs and cats.

DoggyRade is formulated with prebiotics and can help restore electrolytes lost during activity. KittyRade is formulated with glutamic acid to support intestinal function, as well as taurine to promote heart and eye health.

Bone Apptit

Bon voyage, and bone apptit. In May 2021, global hospitality company Hilton launched a culinary menu for dogs, available at more than 30 of its hotel locations in the United Kingdom and Ireland.

The menu was curated in partnership with veterinary nutritionists and includes four mouth-watering courses: Beef Doguignon, a slow-cooked beef brisket with mashed potatoes, carrots, green beans, sweetcorn and gluten-free gravy; Mutt Roast, a gluten-free tomato pasta topped with cheddar cheese; Earl Greyhound, a beverage blend of lavender, rose petals, lime flower and orange flowers to promote calmness in dogs; and Tailwagger Creek, a non-alcoholic dog wine made from elderflower, nettle, ginseng, lime flower and black carrot.

In an effort to encourage travelers to bring their canine companions along, Hilton has branded 74 of its global hotels as dog-friendly getaways. These locations include dog beds and water bowls, Bone Apptit room service at the select 32 locations, and other amenities for tail-wagging tourists.

Keep up with the latestpet food trendson our Trends page.

Excerpt from:

Putting the 'human' in pet product humanization - Pet Food Processing

Dr. Michael Daignault| Opinion contributor

The 5 best foods for hair growth

If you want longer hair, there are certain foods that promote hair growth and are good for overall hair health. Buzz60's Sean Dowling has more.

Buzz60

The popular beauty supplement biotin is trending again, but not for the reasons you think.

Concern over biotin's potential interaction with COVID-19 diagnostic tests peaked right about the same time the US government was sending out millions of rapid antigen tests to peoples' homes. The widespread news coverage and interest suggested that a lot of Americans take biotin as a supplement or as part of a daily multivitamin.

So, does taking biotin as a supplement interact with rapidtests? Short answer: Very unlikely. But more on that later.

This spotlight on biotin is a great opportunity to examine whether the scientific evidence supports the many results promised by the beauty industry.

Biotin is part of the essential vitamin B-complex. It helps the body convert food into energy and regulateblood sugar levels. It also plays key role in helping cells function well.

The recommended daily allowance for biotin is 100mcg (0.1mg). The biotin in multivitamins is typically 30mcg, or 0.03mg. This amount is easily obtained from a well-balanced diet. Foods that contain the most biotin include eggs, fish, meat, seeds, nuts, and certain vegetables (such as sweet potatoes). As such, biotin deficiency is a rarely made diagnosis by physicians.

However, it can be quite debilitating for patients. Biotin deficiency presents with multiple symptoms including brittle nails, thinning hairand a scaly red rash around the eyes, nose, mouthand perineum. Some research has shown that high-dose biotin supplementation can help in particular with improving the strength of nails in those with known deficiency. However, the research studies are flimsy when it comes to whether supplementing with biotin will further strengthen or accelerate growth in the hair and nails of healthy people.

The beauty industry extrapolated the results of limited research and a small number of case studies to promote biotin supplements for all matter of applications, including skin, hairand nail growth and quality.

Many people take melatonin as a sleep aid: What you should know before you do

Their promises appear to be based on three research studies that feature daily supplementation of 2.5mg of biotin - 25 timesthe daily recommended dose in participants with brittle nails. In the most oft-cited study, eightwomen who had their nail samples obtained before and after 6 months of daily biotin supplementation, demonstrated an increase in nail thickness by 25%. A second study of 45 patients showed that 91% of them had firmer and harder fingernails after an average of 5.5 months. A third retrospective study found that 63% of patients had improved nail quality after 6-15 months of treatment.

While all threestudies demonstrate improvement in nail quality in those who had been diagnosed with brittle nails, none included a placebo group for comparison, an important aspect of a randomized-control trial that increases a studys validity and worth. However, what this research does indicate is that biotin supplementation likely helps in patients withknownbiotin deficiency. What these studies don't demonstrate, is what effect biotin supplementation will have in people with normal nails.

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The evidence to support biotin supplementation for improved hair and skin health is even weaker. There exists only a small number of case reports with claims that biotin supplementation promoted hair health or resolved skin rashes and these were only done in children again without a comparable placebo group.Case studies represent a low strength of evidence when it comes to research studies.

The good news? Supplementing with high-dose biotin is unlikely to be toxic (however high doses can cause stomach distress in some individuals). And since biotin is water-soluble, the body does a pretty good job of excreting excess amounts through urination.

Prior to the pandemic, the FDA had cautioned that high doses of biotin could affect the results of blood tests measuring thyroid levels and other hormones, and some heart tests, which we commonly order in the ER to assess for congestive heart failure and heart attacks. Many lab tests use biotin technology due to its ability to bond with specific proteins which can be measured to detect certain health conditions. In theory, if you take a high-dose biotin supplement, it can produce "false-positive" or "false-negative" blood test results.

Fact check: Experts debunk claim that COVID-19 antibodies turn breast milk green

COVID-19 rapid antigen and PCR tests are nasal (and sometimes saliva) tests. Its extremely unlikely that theres sufficient biotin in the nose and mouth (if any at all) to alter either a rapid antigen or PCR test. And almost all COVID-19 diagnostic tests, including the ones we were sent in the mail, do not include biotin technology, so theres no need to worry about that potential interaction.

Most people are not biotin deficient given that it is abundant in a variety of food sources. But if you think you are suffering from brittle nails or other symptoms, consult your doctor before self-diagnosing yourself with a biotin deficiency. Any of these ailments alone could be caused by a wide range of conditions that should be addressed before landing on biotin deficiency as the cause. And the current available scientific evidence does not strongly support high-dose supplementation with biotin in healthy individuals for cosmetic purposes, including nail/hair growth and/or strengthening.

The answer may surprise you: Can spending more time in the sauna save your life?

Read this article:

Everyone is talking about biotin supplements. Here's what you need to know. - USA TODAY

Jessica PetersonGetty Images

Lets face it: Supplementsas common as they arecan be confusing. Even if you know your vitamin Cs from your Ds, you may benefit from a refresher course on which to take, and what they can do for you. To get up to speed, take a walk with us through the virtual vitamin aisle.

TrueYou Mighty Strong Plant-Based Calcium

Calcium is the most abundant mineral in the body and makes up the structure of your bones and teeth. This mineral helps with blood vessel dilation and contraction, blood clotting, muscle function, nerve transmission, and hormone secretion, says Brittany Michels, MS, RDN, LDN, registered dietitian at The Vitamin Shoppe. Women 50 and younger need 1000mg of calcium daily, while women over 50 require 1,200 mg of calcium daily. Consider supplementation if your dietary intake is low. Michels recommends TrueYou Mighty Strong Organic Calcium, which also includes vitamin D and magnesiumresearch has shown adequate levels of magnesium help your body absorb vitamin D and calcium.

TrueYou Head Over Heels Enhanced Collagen Powder

While calcium is the most abundant mineral in the body, collagen is the most abundant protein. You may know it for having hair and skin benefits, but the mineral actually makes up the structure of our hair, skin, nails, joints, bones, cartilage, tendons, and gut.

Since the amount of collagen in the body decreases as you age, supplements are an important option, according to Michels. Bone broth is a wonderful dietary source of collagen, and TrueYou Head Over Heels Enhanced Collagen Peptides is another good choice. The blend of collagen peptides and hyaluronic acid purports to maintain healthy and hydrated skin and nails. It may also help keep estrogen levels in balance, she says.

TrueYou Cool As a Cuke Stress & Mood Support

In addition to providing a calming effectmaking it a helpful before-bed additionmagnesium is a mineral thats needed in more than 300 processes in the body. They include helping with blood pressure and blood sugar management, nerve function, and immune support.

Stress and lack of sleep can deplete levels in your body, and low magnesium levels have been shown to lead to an increase in a C-reactive protein (an inflammatory marker).

Food sources of magnesium include leafy greens, almonds, cashews, peanuts, pumpkin seeds, and black beans. Women who are unable to meet needs via their diet should consider supplementation, Michels says. The TrueYou Cool as a Cuke Stress & Mood Support includes magnesium as well as adaptogens (ashwagandha and lemon balm) that counteract the negative effects of stress on hormones.

Omega-3 Fish Oil with Vitamin D3

Omega 3s support heart, brain, mood, joint, and overall health. Not all omega 3s are the same, however. Active omega 3 dietary sources (EPA and DHA) include seafood and algae, Michels says. Inactive omega 3 dietary sources (ALAthese need to be converted into EPA and DHA by your body) include flax seed oil, flax seeds, chia seeds, hemp hearts and walnuts.

If youre not getting enough omega 3s in your diet, consider supplementing. To meet baseline needs, aim for one of the following or a combo of these: two to three servings of low-mercury seafood (like sardines or shrimp) weekly or a minimum of 1,200 to 2,000 mg daily of combined DHA and EPA in an omega 3 fish oil or algae omega supplement, Michels says.

Vitamin D

This fat-soluble vitamin is one of the most important for healthy bones. It's also commonly one that women are deficient in. Of its countless functions, Vitamin Dfound in fatty fish, egg yolks, mushrooms, and milkis responsible for turning on and off our immune system and powering the body. Low levels of vitamin D are also linked to anxiety, depression, decreased pancreatic function, and hormonal influences, Michels says.

Delayed Release Probiotics

Probiotics are the beneficial bacteria found in your gut. Specific probiotic strains are linked to the health of key areas in the body, such as our immune system, digestive health, respiratory health and mental health, Michels says.

Your guts bacteria balance can be thrown off by many factors, including, but not limited to, unmanaged stress, antibiotic usage, and digestive disorders, Michels says, which is why taking a probiotic may be helpful.

TrueYou Perfect Ensemble Once Daily Multivitamin

Made it through the virtual aisle and feeling overwhelmed? Multivitamins are your best friend. A multivitamin is the most comprehensive supplement option for those desiring full nutrient coverage, Michels says. They are designed to fulfill potential nutritional gaps in the diet.

TrueYou Perfect Ensemble Organic Womens Once Daily Multivitaminwhich comes in a 50+ version as wellprovides a comprehensive profile of antioxidants, vitamins, and minerals, Michels says.

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Your Guide to the Most Common Types of Supplements - WomansDay.com

The global vitamin and dietary supplements market is expected to exhibit a CAGR of 4.9% from 2020 to 2025 with capsules and tablets being the most consumable dosage form of supplements. Powder is expected to emerge as the fastest-growing dosage form from 2020 to 2025 with a projected CAGR of 6.4% from 2020 to 2025.

Vitamins and Dietary Supplements Industry Category Intelligence

Multivitamins have been traditionally used as supplements along with diet to improve nutritional qualities and lower health problems, like osteoporosis and arthritis. With the onset of COVID, there has been a public notion that vitamins could reduce the severity of symptoms (although it is not a cure) for COVID. Manufacturers of multivitamins are capitalizing on this and the demand for multivitamins has increased since 2020. Overall, thevitamins and dietary supplements marketis expected to expand at a CAGR of 4.9% from 2020 to 2025. However, as time progresses, these myths have been debunked by several studies. For example, NCBI has published articles stating that CBD-based supplements are not a cure for coronavirus or any other maladies caused due to the infection of coronavirus.

One of the recent trends witnessed in the market is the entrance of vitamin and dietary supplement manufacturers into the food and snacks business. For example, Chinese dietary supplement provider BY-HEALTH is investing in product diversity and is segregating its products between food and snacks with light functionalities and supplements with strong functionalities. Protein bars have become the choice of snack for such dietary supplement suppliers. The company, by the end of 2020, has received filing approvals for 112 health foods and registration approvals for over 140 health foods.

Vitamins and Dietary Supplements Industry Category Intelligence Highlights:

Grab your copy, or request for a free sample of the Vitamins and Dietary Supplements Industry Procurement Intelligence Report, published by Grand View Research for In-depth details regarding supplier ranking and selection, sourcing, and pricing criteria & strategies

Vitamins and Dietary Supplements Types

Vitamins and Dietary SupplementsIndustry Supplier Intelligence Capability based ranking & selection criteria with weightage:

Operational Capabilities Weightage

Functional Capabilities Weightage

By Form (45%)

By manufacturer type (35%)

Other services offered by manufacturer (20%)

Vitamins and Dietary Supplements Industry Cost Intelligence Highlights:

Grand View Research has identified the following key cost components for availing vitamins and dietary supplements manufacturing:

List of Key Suppliers in the Vitamins and Dietary Supplements Industry

Add-on Services provided by Grand View Research Pipeline:

Should Cost Analysis

Component wise cost break down for better negotiation for the client, highlights the key cost drivers in the market with future price fluctuation for different materials (e.g.: steel, aluminum, etc.) used in the production process

In the vitamins and dietary supplements procurement intelligence study, we have estimated and forecasted pricing for the key cost components. Raw materials are the largest cost component of vitamin and dietary supplements manufacturing cost. It accounted for more than 50% of the share in the overall cost of manufacturing. Raw materials include the combination of Vitamin A to Vitamin K. Among these, Vitamin A and Beta Carotene hold the major cost share of 9% and 7% respectively. The price of Vitamin A is expected to fluctuate during the period of forecast, continuing its trend from 2015. Whereas, Beta Carotene price is expected to remain stable in the next five years.

Rate Benchmarking

Offering cost transparency for different products / services procured by the client. A typical report involves 2-3 case scenarios helping clients to select the best suited engagement with the supplier

The dosage form is one of the most important aspects while analyzing the rate benchmarking of multivitamins and supplements. In our research, we have analyzed the rates of vitamin A in three major types of the dosage form; solid (Tablets and capsules), liquids and powders. By using rate benchmarking analysis, we found that solid forms of multivitamins are ~50% more cost-effective than liquid and powders. Solid forms also have longer shelf life than the other two dosage forms. Therefore, most of the multivitamin and supplements manufacturers allotted more than 60% of the overall production capacity to produce multivitamin tablets and capsules. Only 20% of the production line is used for liquid and powder supplements production.

To gain a comprehensive understanding of the other aspects of rate benchmarking, please subscribe to our services for the complete report.

Salary Benchmarking

Determining and forecasting salaries for specific skill set labor to make decision on outsourcing vs in-house.

Our research indicates that Nestl production managers earn 40%-50% higher salaries than production managers from other key competitors like Amway, GlaxoSmithKline. However, the YoY increment rate in such companies largely depends on KRAs.

Supplier Newsletter

A typical newsletter study by capturing latest information for specific suppliers related to: M&As, technological innovations, expansion, litigations, bankruptcy etc.

It is cumbersome for any organization to continuously track the latest developments in their supplier landscape. Our newsletter service helps them remain updated, to avoid any supply chain disruption which they may face, and keep a track of the latest innovations from the suppliers. Outsourcing such activities help clients focus on their core offerings.

Brief about Pipeline by Grand View Research:

A smart and effective supply chain is essential for growth in any organization.Pipeline division at Grand View Researchprovides detailed insights on every aspect of supply chain which helps in efficient procurement decisions.

Our services include (not limited to):

Sourcing / Procurement Intelligence best practices followed in the industry, identifying standard KPIs and SLAs, peer analysis, negotiation strategies to be utilized with the suppliers, and best suited countries for sourcing to minimize supply chain disruptions

Browse throughGrand View Researchs collection of procurement intelligence studies:

Contract Research Organization Market Procurement IntelligenceThe global CRO market is expected to witness sustainable growth (CAGR of 6.4%) from 2020 to 2025 due to the increasing global need for drug development and investments by pharma giants in R&D, owing to the patent expiration of blockbuster drugs.

Sugar Processing Market Procurement IntelligenceThe global sugar processing market was valued at 166 million MT in 2020 and it is expected to grow at a CAGR of ~2% from 2021 to 2027 to cross 200 million MT in terms of volume in 2027. The growth of the market is majorly driven by the high demand generated from the food and beverages industry.

Media ContactCompany Name: Grand View Research, Inc.Contact Person: Sherry James, Corporate Sales Specialist U.S.A.Email: Send EmailPhone: 1888202951Address:Grand View Research, Inc. 201 Spear Street 1100 San Francisco, CA 94105, United StatesCity: San FranciscoState: CaliforniaCountry: United StatesWebsite: https://www.grandviewresearch.com/pipeline/vitamins-dietary-supplements-market-procurement-intelligence-report

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Vitamins and Dietary Supplements Industry Procurement Intelligence 2020-2025 | Rising popularity of vitamins and dietary supplements; with Powder is...

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The AG1 formula has been perfected over the course of a decade. The formulation uses a perfect balance of vitamins and minerals that are crucial for a well-functioning nervous system, and a fundamental building block of a strong immune system. The superfood formula provides the antioxidant equivalent of 12 servings of fruits and vegetables per scoop. Plus, antioxidants counteract the impact of free radicals, which are highly unstable molecules that can cause cell damage within your body. Then there are dairy-free probiotics and prebiotics. The probiotics support your gut health, enhance nutrient absorption, and strengthen your immune system. Prebiotics are special types of fiber that feed those probiotics so they can multiply and establish an ongoing presence in your digestive system.

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Europeans consume sufficient macronutrients fat, protein, and carbohydrates. Micronutrient intake, on the other hand, is lagging.

How can governments address these micronutrient gaps? Maaike Bruins, lead scientist at DSM Nutritional Products, is advocating for fortification policies to help move the needle.

Vitamins and minerals play an important role in all our body organs and functions, said Bruins at a recent European Food Forum (EFF) event. They are important for immunity, the brain, for gut health, heart health, and so on.

Essential minerals include calcium, iron, magnesium, potassium, and zinc. Some of the best known essential vitamins including vitamins A, D, E, C, and B12.

When vitamin or mineral intakes are low, invisible changes such as changes in biomarkers in the blood, or subclinical signs such as fatigue, can occur. This is why we sometimes talk about hidden hunger, since the symptoms may not be visible, the lead scientist explained.

Across Europe, and notably in Denmark, the Czech Republic, Italy, and France, at least three vitamins are considered vitamins of concern: vitamin C, B12, and the vitamin most associated with the COVID-19 pandemic vitamin D.

Indeed, a recent report from the European Food Safety Authority (EFSA) suggests that vitamin D status is too low in the majority of European countries, with vitamin D status being determined not only by diet, but also by a large extent by the sun we are exposed to.

The EFSA Panel also highlighted that no more than 5% of people in Europe meet the dietary intake recommendations, Bruins told delegates.

Vitamin D status is particularly poor in some countries. A review of all published data on vitamin D status in northern European countries, for example, revealed dire findings.

In this geography, citizens are receiving too little from sun exposure and from dietary intake. The majority of the countries have mean levels around insufficiency of 50 nmol/L, which is a level below which the risk of bone problems increases, we were told.

Throwing the spotlight on DSMs native country, the Netherlands, reveals similarly problematic results.

The Dutch National Food Consumption Survey, conducted between 2012 and 2016, showed that vitamin D levels are extremely low from the base diet.

Specifically, 0.8% of the Dutch population had adequate intake of vitamin D from the base diet, 1% had adequate intake from the base diet and fortified foods, 9% has adequate intake from the base diet, fortified foods and food supplements, and 89% of the population did not meet adequate intake of vitamin D from any source.

The survey concluded that food supplements help the Dutch to meet their vitamin D requirements, with findings suggesting policy addressing food fortification could also contribute to increased intake.

Policy is needed, stressed Bruins, as was also concluded by the recent EFSA report.

Amongst the countries that acknowledge they have a problem with vitamin D intake is Finland.

Finland may be a good example that sees the urgency of addressing vitamin D in their country, particularly because they are situation in a very northern part of Europe, explained the lead scientist.

To address insufficient vitamin D levels in its population, the Finnish government recommends the food industry fortify fluid milk products and fat spreads with vitamin D.

The Finnish government also recommends the population eat fish at least three times per week, and take vitamin D supplements.

The vitamin D programme was instigated in 2000, and a study conducted by researchers analysing vitamin D levels between 2000 and 2011 revealed it has made an impact on micronutrient levels.

The vitamin D status of the Finnish adult population has improved considerably during the time period studied, noted the 2017 study published in The American Journal of Clinical Nutrition.

This increase is mainly explained by food fortification, especially of fluid milk products, and augmented vitamin D supplement use.

The study authors continued: When consuming vitamin D sources based on the nutritional recommendations, vitamin D status is sufficient, and supplementation is generally not needed.

At the EFF event, DSMs Bruins stressed the research revealed those severely deficient were benefiting from the governments vitamin D recommendations.

However, looking more broadly, voluntary fortification in the market is very low, with just a small percentage of food and drink product being voluntarily fortified with vitamins and minerals.

There is much to gain if real problem nutrients are targeted, and businesses incentivised to fortify their goods, she continued. In the US, you see manufacturers fortify with public health problem nutrients like vitamin D. They are incentivised because they can put it on their packaging.

Bruins concluded: Fortification of foods helps to address micronutrient gaps, and you can see that policy can improve the intake of problem nutrients, as exemplified by vitamin D in Finland.

Source: The American Journal of Clinical NutritionThe positive impact of general vitamin D food fortification policy on vitamin D status in a representative adult Finnish population: evidence from an 11-y follow-up based on standardized 25-hydroxyvitamin D dataPublished May 10 2017DOI: 10.3945/ajcn.116.151415T. Jskelinen, ST. Itkonen, A. Lundqvist, M. Erkkola, T. Koskela et al.

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DSM on tackling vitamin D deficiency with food: 'Policy can improve intake' - FoodNavigator.com

Theres an important relationship among your nutritional status, immune health, risk of infection, and ability to recover from illness (1, 2, 3).

Poor nutrition is associated with inflammation and oxidative stress, which compromise immune health. Both inflammation and oxidative stress are elevated when you have COVID-19 (1, 2).

The World Health Organization declared the novel coronavirus a pandemic in March 2020. The viruss full name is severe acute respiratory syndrome coronavirus (SARS-CoV-2), and the illness it causes is called COVID-19 (4).

COVID-19 negatively affects nutritional status because it decreases appetite and may limit your access to nutritious foods during confinement, yet it simultaneously increases your bodys need for nutrients, such as vitamin D (3, 5, 6).

Diet and nutrition can help support your immune health if you have COVID-19, especially if you consume foods with antioxidant and anti-inflammatory properties (1, 2, 5, 6, 7).

Its important to note that this is an emerging area of research. These foods wont prevent you from contracting the novel coronavirus or cure the disease, but they have been shown to support immune health.

This article lists key nutrients, foods, and nutrition practices that may be beneficial for people who have COVID-19 or are recovering from it.

Vitamin D is the most frequently discussed micronutrient among nutrition experts for the management of COVID-19 (5).

This fat-soluble vitamin and hormone exerts an anti-inflammatory effect by suppressing overactivity of the immune system, according to newer and older research (1, 5, 8, 9).

In the body, vitamin D acts on angiotensin converting enzyme 2 (ACE2), a protein receptor found in the lungs and fat tissue (1, 7).

The novel coronavirus binds to ACE2 at the beginning of an infection, potentially leading to acute respiratory distress syndrome and severe illness in people with COVID-19 (10).

However, vitamin D interacts with the ACE2 receptors, potentially preventing the virus from binding to them, and reducing complications associated with COVID-19 (1, 10, 11).

Vitamin D may also play a protective role and support healing of damaged tissues, primarily in the lungs (10).

On average, people make approximately 80% of their vitamin D when their skin is exposed to sunlight (ultraviolet light) and get the remaining 20% from their diet (8).

As a result, taking vitamin D daily may be a good idea if youre in confinement due to COVID-19 and have little sunlight exposure (5).

However, some medications may interact with vitamin D supplements including blood thinners, which are common among people with COVID-19 as a result of the increased risk of blood clotting.

Thats why its best to speak with a healthcare professional before you start taking vitamin D supplements regularly.

Increasing your intake of vitamin D-rich foods while you have or are recovering from COVID-19 is a great way to reduce the risk of a vitamin D deficiency and potentially improve your immune response.

Here are seven foods rich in vitamin D, along with the amount of the vitamin each contains (12, 13, 14, 15, 16, 17, 18):

Wild mushrooms are a vegetarian source of vitamin D. Their levels vary depending on the type of light they were exposed to as they were growing, according to older research (19).

Vitamin D may help protect your lungs during novel coronavirus infection by disrupting viral attachment in your body. Several foods are rich in vitamin D, including cod liver oil, salmon, herring, and some wild mushrooms.

Carotenoids are antioxidants as well as pigments (red, green, yellow, and orange). Theyre found in nature in some colorful algae, bacteria, fungi, plants, fruits, and vegetables, some of which you can include in your diet (20, 21).

Of the 700 carotenoids identified in nature, only about 30 have been found in the human body. One of these is vitamin A and its precursor, beta carotene (20, 22, 23).

Vitamin A is a fat-soluble antioxidant carotenoid. It has anti-inflammatory properties, and research has shown it may be beneficial for managing pneumonia and respiratory infections (1, 24, 25, 26).

In the case of COVID-19, studies indicate that vitamin A reduces inflammation and oxidative stress, enhances the immune response, and may decrease the severity of the disease (24, 25).

Researchers think it protects the ACE2 receptors, similarly to vitamin D, and may work on several other molecular targets to combat COVID-19 (24, 25).

Some people may develop vitamin A deficiency during infections such as COVID-19, and this may actually increase the severity of the disease. If this happens, you might need to take vitamin A supplements (25).

However, drug interactions are also possible if youre taking vitamin A supplements, so make sure you speak with a healthcare professional before taking them.

Dark green leafy vegetables and organ meats, particularly liver, are rich sources of vitamin A.

Here are eight foods rich in vitamin A, along with the % of the DV per 100 grams of each (27, 28, 29, 30, 31, 32, 33, 34):

Vitamin A is a carotenoid that may help provide powerful protection against infections, including COVID-19. Food sources include liver, dark green leafy vegetables, and pigmented vegetables such as sweet potatoes and carrots.

Zinc deficiency has been associated with an increased risk of infections and poorer outcomes in those with COVID-19 (1, 35).

Zinc is regarded as one of the most important minerals. Research has shown that its antioxidant and anti-inflammatory properties may reduce the risk of heart disease, may support eye health, and are essential for immune health (36, 37, 38, 39).

In COVID-19, zinc may reduce the risk of getting a bacterial infection at the same time and decrease activity of the ACE2 receptors, which are targets of the novel coronavirus (40).

It also protects the health of the lung tissue and may be a therapeutic additional treatment for COVID-19. Studies on this are now underway (41, 42, 43, 44).

If youve received a diagnosis of zinc deficiency, your doctor may have recommended that you take zinc supplements. However, be careful not to take too much, because zinc is toxic in excess amounts. Stick to the dose your doctor recommends (45).

Here are seven foods rich in zinc, along with the % of the DV per 100 grams of each (46, 47, 48, 49, 50, 51, 52):

Zinc is an essential mineral with anti-inflammatory properties that may benefit people with COVID-19. Rich food sources include ground beef, cashews, and hemp seeds.

Omega-3 polyunsaturated fats are a category of fatty acids shown to have anti-inflammatory health benefits, including for brain health, heart disease, and rheumatoid arthritis (1, 9, 53, 54).

These omega-3 fats, specifically eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA), may improve recovery in people with COVID-19 (55).

However, higher quality research in humans is needed before healthcare professionals may recommend taking it for this purpose.

Omega-3 fats reduce inflammation and the potential for the cytokine storm in COVID-19, which is hyperactivity of the immune system that causes negative symptoms.

Theyre thought to do this by becoming part of cell membranes of various tissues throughout the body and preventing the production of pro-inflammatory compounds (56).

Another potential benefit of omega-3 fats in treating those with or recovering from COVID-19 is their role in improving mood, anxiety, and depression all of which may be worsened by the novel coronavirus pandemic (57, 58).

Research is underway to determine the therapeutic role of omega-3 fats for COVID-19.

Here are eight foods rich in omega-3 fatty acids, along with the amount of omega-3s found in each. Note that these contain different types of omega-3s (12, 15, 17, 29, 59, 60, 61, 62):

As you may have noticed, many foods rich in omega-3 fats are also rich sources of vitamin D.

Omega-3 polyunsaturated fats are known for their anti-inflammatory health benefits and may help treat COVID-19. Foods rich in omega-3 fats include salmon, sardines, and chia seeds.

Vitamin C is an antioxidant vitamin that supports immune health in people of all ages (63).

Animal and human studies have found that vitamin C may reduce oxidative stress, improve endothelial function to guard against heart disease, and support recovery from the common cold (64, 65, 66).

Emerging research demonstrates that giving vitamin C to people with COVID-19 may support recovery and improvement during the disease course (44, 66, 67).

Vitamin C has a potential role in the prevention and management of pneumonia and bacterial infections such as sepsis, although some in the scientific community question its use (66, 67).

Preliminary evidence suggests that taking vitamin C may help those with COVID-19, but more studies in humans are needed (68).

Here are eight foods naturally high in vitamin C, along with the % of the DV per 100 grams of each (69, 70, 71, 72, 73, 74, 75, 76):

Vitamin C is an antioxidant vitamin that supports immune health and is known to reduce the risk of pneumonia. This nutrient shows promise as a treatment for COVID-19, and more research is currently underway.

COVID-19 negatively affects nutritional status, and a healthy, functional immune system is paramount to reducing the risk of infection and supporting recovery.

Researchers are looking with great interest at vitamin D, carotenoids, vitamin A, zinc, omega-3 fatty acids, and vitamin C to determine their potential health benefits as complementary treatments for COVID-19.

There is currently no clinical evidence that a low histamine diet is beneficial to those with or recovering from COVID-19. More research in humans is needed.

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5 Foods to Eat If You Have COVID-19 - Healthline

ALBANY, N.Y., Feb. 14, 2022 /PRNewswire/ -- Substantial demand for digestive enzyme supplements in the food and feed industries has created abundant lucrative avenues in the pancreatin market. Recent focus on unveiling low-cost pancreatin and novel formulations for digestive enzymes and nutraceuticals are reinforcing the revenue growth. The global valuation is projected to reach US$ 175.7 Mn by 2031.

Advancements in enzyme technologies especially pertaining to microbial sources have broadened the horizon, notes an in-depth study on the pancreatin market. One of the emerging applications is in the leather industry. Increasing preference of pancreatin over alkaline proteases in leather processing will drive revenue gains during the forecast period (20212031). This can be primarily attributed to the fact that pancreatin contains a mix of multiple enzymes, thus making it suitable for a range of leather types.

Several pharmaceutical companies have reaped enormous revenue gains from the application of pancreatin in enzyme formulations. The authors of the study on the pancreatin market have estimated that the valuation of the segment will reach US$ 155.7 Mn by 2031. Furthermore, growing use in animal feed applications are generating value-grab opportunities for market players.

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Key Findings of Pancreatin Market Study

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Pancreatin Market: Key Drivers

Pancreatin Market: Regional Growth Dynamics

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Pancreatin Market: Key Players

Several manufacturers in the pancreatin market are leaning on reducing the cost of processing in order to lower the cost of final product. Furthermore, key players are keen on diversifying their product portfolio and constantly conducting R&D for novel formulations in a bid to consolidate their shares.

Prominent players in the pancreatin market are Hepalink Group, SG Pharma Pvt. Ltd., Creative Enzymes, Hetero Healthcare Limited, Shreeji Pharma International, Wellona Pharma, Fengchen Group Co., Ltd., Biozyme, and Nordmark.

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Global Pancreatin Market: Segmentation

Pancreatin Market by Form

Pancreatin Market by Source

Pancreatin Market by Application

Pancreatin Market by Region

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Pancreatin Market to Advance at CAGR of 5.7% During 2021 to 2031; Growing Consumption of Food & Feed Enzymes Generating Revenues Gains, Notes TMR...