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Category Archives: Evolution

Dr. Langer on the Evolution of Molecular Testing in Advanced NSCLC – OncLive

Posted: November 15, 2021 at 11:31 pm

Corey J. Langer, MD, professor of medicine, University of Pennsylvania, director, Thoracic Oncology, Penn Medicine, discusses the evolution of molecular testing in advanced nonsmall cell lung cancer.

Corey J. Langer, MD, professor of medicine, University of Pennsylvania, director, Thoracic Oncology, Penn Medicine, discusses the evolution of molecular testing in advanced nonsmall cell lung cancer (NSCLC).

Molecular testing is routinely ordered for patients with de novo metastatic NSCLC or recurrent disease following prior curative-intent therapy, Langer explains. Although testing isnt ordered for all patients, it should be done in patients with nonsquamous NSCLC regardless of smoking history and nonsmokers or remote former smokers regardless of histology.

Additionally, it is possible routine molecular testing will be done for all patients with NSCLC in the next 1 to 2 years because an increasing number of molecular abnormalities, including EGFR mutations and MET amplifications, have been identified in patients with squamous histology, Langer concludes.

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MCU Head Of Visual Development Ryan Meinerding Dishes On The Evolution Of Iron Man’s Armors – Exclusive – Looper

Posted: at 11:31 pm

He continued, "I pitched a number of those elements to Jon [Favreau] and that time, and some of that made it into the movie. Michael Riva and his team did such a great job on Tony's workshop."

Fans may have noticed a similar vibe between Iron Man's first super suit and his first on-screen one. Well, that was intentional. "As far as the Mark 1, I was looking at what Phil [Saunders] and Adi [Granov] were doing with the Mark II and III and thought I could try and take the comic reference for Iron Man's first grey suit and add as much reality to it as I could,"Meinerding explained."So that meant keeping the center RT and designing forms around it that allowed highlights to look like they are radiating outward from that center light. I was also looking at doing different finishes on the different parts of the suit so it would appear as if they were coming from multiple different sources."

Among the aesthetics, though, came the technical bits. "There was a degree of trying to include enough bulkiness so Tony could've hidden what he was working on, as well as showcasing how protective and strong the suit is. I added belt drives to the legs to keep the drive mechanism outside the armor of the suit mostly to add a bit more interest and realism," Meinerding noted.

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MCU Head Of Visual Development Ryan Meinerding Dishes On The Evolution Of Iron Man's Armors - Exclusive - Looper

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Wonder Woman Evolution #1 Preview: Wonder Woman Has This Covered – Bleeding Cool News

Posted: at 11:31 pm

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Welcome to Friday Night Previews, where we pad our article coun er, provide the readers of Bleeding Cool with a valuable service by running all of the Marvel and DC previews for the week "enhanced" with clickbait headlines and snarky commentary. Except that this week, Friday Night Previews has become Saturday Night Previews again because Diamond still can't get their **** together. What did you click on, Steve?! What did you do?! Anyway, the show must go on, amirite? Finally, after another long and sleepless night, we finish the Saturday Night previews with a preview of Wonder Woman Evolution #1, in stores from DC Comics on Tuesday. We have nothing sarcastic to say about this. We just want to go to sleep! Check out the preview beloZZZZZZZZZZZZZZ.

WONDER WOMAN EVOLUTION #1 (OF 8)DC Comics0921DC0630921DC064 WONDER WOMAN EVOLUTION #1 (OF 8) CVR B RILEY ROSSMO CARD STOCK VAR $4.99(W) Stephanie Phillips (A/CA) Mike HawthorneWhisked away from Earth by a distant cosmic entity, Wonder Woman is forced to navigate a series of perilous challenges that push her to the brink both mentally and physically. At stake is the fate of all humanity, with the alien entities casting Diana as Earth's proxy for a trial judging humankind's worthiness to exist in the universe. Can Diana stand trial to save humanity without losing her own? Harley Quinn's Stephanie Phillips teams with acclaimed artist Mike Hawthorne (Daredevil, Deadpool) for his first major DC project, an epic Wonder Woman tale unlike any other!In Shops: 11/16/2021SRP: $3.99

Click here to read more previews of upcoming Marvel and DC comics. Solicit information and cover images taken from PreviewsWorld for Marvel Comics and from Lunar Distribution for DC Comics. New Marvel Comics are released to comic book stores each Wednesday and DC Comics on Tuesdays. Books are available the same day on digital services like ComiXology and the Marvel and DC digital comics stores. Locate a comic shop near you with the Comic Shop Locator.

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BOB MAINDELLE: The evolution of lures for the cold-water season – The Killeen Daily Herald

Posted: at 11:31 pm

In June 2020, and after several years of experimentation, I brought to market a lure called the MAL Lure. This lure was intended to fill a gap where standard presentations fell short, especially during the summer months.

There was once a time when, as a full-time professional fishing guide focused on the year-round pursuitof white bass, I just dreaded the summer months.

This tough fishing would persist right up until turnover, typically in mid to late October.

Through the years, Ive been successful in eliminating unproductive water and getting white bass to biteduring the summer months by making myself become well-versed in interpreting all forms of sonar, andby covering water quickly and efficiently via downrigging.

Still, during those times when downrigging led me to concentrations of white bass, be they located onbottom or suspended, I was hard-pressed to catch more than just a handful immediately after quicklytransitioning from a horizontal approach to a vertical approach.

Slabs, spoons, soft plastics and jigs generated a spurt of initial interest, followed by a very predictable,frustrating shutdown.

I bought some Do-It lead molds and started making my own custom horsehead jigs, complete with theircharacteristic, underslung, spinning blade. That experiment was largely unsuccessful due to my luresslow sink rates, but I did walk away observing that the jigs small spinning blades were a definite triggerfor white bass.

Several summers ago, I decided to venture outside the box to try to crack the code on warm waterwhite bass. I tried doing things on my home waters that no one else was doing. I also traveled to

Queensland, Australia, to fish for Australian bass with professional fishing guide Matthew Langford onLakes Boruma and Somerset during the Australian summer to check out some of the approaches theAussies had come up with using heavy metal tactics for suspended summertime fish holding above thethermocline.

Next, I made my own modified tailspinners. This kept the spinning blade feature of the horsehead jig,but added more weight. I also tried to engineer out of my tailspinners some of the flaws I noted inthose tailspinners already on the market, namely the tendency for the hook to catch on the line or thespinner shaft, and for the blade to spin lazily.

I enjoyed great success with these tailspinners, but I noted that my clients did not do nearly so well onthem as I did. As I analyzed this, I noted that many did not have the fish-fighting experience needed tokeep hooked fish on the hook as the fish was transferred from the water into the boat; we lost way toomany fish during that transition for my satisfaction.

Additionally, many clients had trouble getting and keeping my tailspinners blades turning as needed toattract fish in the first place. So, now I had an effective lure, but it was not user-friendly.

This led me to begin experimenting with inline spinners. I experimented with making my own spinnerswith brass bodies, lead bodies and tungsten bodies, and after many iterations, found something I felthad both fish-catching potential and user-friendly attributes.

I introduced a few clients to the lure and they did very well with it. Then, I began to keep these custom-made versions tied on for general, daily use by all of my clients, including kids and rookies. No one hadany difficulties catching white bass on these lures during the tough summer months. I was amazed atthe results.

Since I had no desire to get into lure production, I brainstormed about how I might have these luresmade to ensure a continuous supply of these for my business. I assumed it was a long-shot actually, Iassumed it was rejection just waiting to happen, but I called the Mepps lure company of Antigo,Wisconsin.

Mepps spinners were the closest in appearance and construct to the effective prototypes I haddeveloped. I worked with them to take characteristics and components from several of their existing

products to form a new product which was deadly for white bass.

Last year, in December, as the water temperature fell to 58, the magic of the MAL Lure all but ranout. The speed at which the lure had to be moved to get the spinner spinning around the lures wire

shaft was too fast for cold-blooded, lethargic fish.

I knew two things for sure first, that a spinning blade is an ultra-attractive feature so far as white bassand hybrid stripers are concerned, and second, that the slab -- a shad-shaped hunk of lead - has puttens of thousands of fish in my boat in the winter months. I wondered what might happen if I combinedthese two powerful entities.

Long story short, this curiosity gave rise to the newest cold-water bait now on the market, introducedand made public this week.

That bait is the Bladed Hazy Eye Slab. This combines a classic, shad-shaped lead body with a smallwillow-leafed spinner blade which is affixed to the lures treble hook using a tiny swivel bonded to thehook.

This bait comes in three sizes: 3/8 ounce, 5/8 ounce, and 3/4 ounce. The baits come powder-coated fordurability in either white or chartreuse.

Most of my field-testing was done last winter in January and February once the water fell into the 50s.

The Bladed Hazy Eye Slab produced extremely well then, and continued to do so even after the severewinter storm took water temperatures into the mid-40s. I have already begun keeping my rods riggedwith these slabs on my boat for times when fish get too finicky to chase hard after the MAL Lures.

On Wednesday, the last 30 of the 100 fish my clients landed were landed on the Bladed Hazy EyeSlab.

In mid-January last year, just before the Tuff-Man Series championship event was to take place, I guidedone of my clients to a 38-plus-pound, five-fish limit of largemouth bass on Stillhouse, all of which werelanded on the standard Hazy Eye Shad -- proof positive that largemouth bass congregate in deep waterin the winter and strike slabs despite the lure being more closely associated with white bass and hybridstriped bass fishing.

I count on the lures I have tied onto the rods I carry on my boat to make my clients successful. Theselures have earned a place on my boat from this time of year right up until the water temperature nips at60F once again in the spring.

If you are like me, you want to see and hold a new lure in your hands before buying it, mainly so you canget a sense for its shape, weight, profile, etc., and see how the fine-tuning which went into the creationof this bait makes it different from a standard slab. These are all things which photographs just cannotconvey. For this reason, Dean Thompson has kindly put on display a full lineup of these new baits atTightlines Premium Fishing Tackle on Business Highway 190 in Killeen.

I also have these available online at http://www.WhiteBassTools.com. Just as necessity truly is the mother ofinvention, I believe fine-tuning inventions is the father of success.

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Colorado Rockies news: The Evolution of the Ball needs a new home – Purple Row

Posted: at 11:31 pm

Ive seen this sculpture since I was a kid and have loved it.

It suddenly disappeared with the construction of McGregor Square, and it needs a new home.

The Evolution of the Ball, designed by Colorado artist Lonnie Hanzon, stood outside the left field gate at Coors Field for years, welcoming fans as they approached a pedestrian bridge over 20th Street on their way into the ballpark. It was the gateway to Coors Field for people like myself, the routine ballpark travelers on RTD light rails walking in from nearby Union Station, or the ballpark connoisseurs that soaked in the magic of Coors Field from the outside in.

The Evolution of the Ball was a staple until it wasnt.

When McGregor Square was constructed, the sculpture was forcedly removed. The City of Denver mandated that a fire lane be placed on the north side of the new 13-story development, meaning the Evolution of the Ball had to go. We have not seen the $100,000-plus sculpture since removal, and fans like myself are forced to reminisce on a key ballpark feature that is now a thing of the past.

I seriously think the only thing missing from All-Star Week was this sculpture.

Where can we preserve the artistic integrity? The pedestrian walkway in left field was as much of a welcome as anywhere with this art behind it. Unless the sculpture is distastefully plastered right behind the Player statue at home plate, there arent many more locations around the park where it can serve its original purpose as a gateway.

Where can it go from here? Thanks to the help of Apple Maps, computer screenshots and creative brainstorming, heres our preliminary options. (Well likely need Mr. Hanzons blessing for any of these sites, but hopefully well be able to see it before long.)

The designated Rockies-sponsored parking lots at Coors Field are beyond right-center field, lining the train tracks that lead out of Union Station to the northeast. If a gateway to the ballpark is what this sculpture is intended for, placing this monument just outside of the centerfield gate is a surefire way to make sure baseball fans walk underneath it again. It might get pushed too close against the brick of Coors Field, but some parking lot remodeling could make this a fitting reality.

I must admit that my five-year-old self fell in love with this sculpture for how playful and fun it looked. If it served as a gateway to the left-field playground at Coors Field, it stays close to the original placement, serving a kid-friendly purpose, and its arguably more visible than it was in the first place.

Let it be known that this sculpture was intended for Coors Field and Coors Field only.

but

The Evolution of the Ball could find a poetic new placement at the aptly-named arena across Lower Downtown. Theres currently a huge concrete walkway outside Ball Arena where this sculpture could go, and its arguably perfect if the baseball future of this sculpture has passed.

They would probably need to replace the bronze baseball atop the sculpture, however, and this alone will have Rockies fans like myself feeling a certain way.

The mini-diamond near the center of this aerial photo is a kids field on the first base side of the concourse. Just to the right of it is a gate that welcomes fans to Colorado spring training, and a small walkway leads people through the Rockies backfields and batting cages and into the stadium itself. Its about as close as you can get to the original feeling youd get walking into Coors Field with the statue in front of you.

The Evolution of the Ball is not exactly designed to fit the southwest architecture of Salt River Fields, so it might look a little out of place in Scottsdale. (That doesnt make it any less cool, though.)

The Rockies originally announced that Double Angel Ballpark would house their alternate site operations in April 2021 to accommodate the delayed minor league season. The decision was eventually reversed and the club moved the operation to Salt River Fields, where Rockies players could easily play games against other MLB affiliates at spring training sites.

Maybe the complex in Parker is fit for a delayed thank you, in the form of one of the most gorgeous art installations on the planet.

There is an entrance to Double Angel Ballpark that would be a perfect place for a give-back. In the same youthful spirit of cherishing that sculpture like I did when I was a kid, what better way to commemorate this installation than placing it at some amateur fields?

Now its time for the more somber, less-optimistic headlines of the day: its time to imagine Jon Gray in something other than purple.

Mike Petriello of MLB.com takes a deep look into Grays home and road splits; while they are near-identical at first glance, Grays third time through the lineup in Denver is a little less favorable than elsewhere. If hes to take on duties as a workhorse elsewhere, a new team could be getting even more of Gray later in games than they first bargained for.

The reality is also sinking in that Nolan Arenado swiped a Gold Glove away from Denver this time around, and the related offseason discussion has now ensured. Our friend Noah Yingling of Rox Pile covers defensive stats and voting guidelines, all while analyzing how and why Ryan McMahon was left without some hardware.

Surprise Saguaros 4, Salt River Rafters 3

It was a rather forgettable day for Rockies prospects in the Arizona Fall League on Monday. Matt Dennis took the start for the Rafters and allowed three earned runs in three innings, letting up four hits in his 56 pitches. Colorado hitters were a combined 2-for-9, while Willie MacIver and Ryan Vilade each recorded a single.

The Rafters and Saguaros only played seven innings due to available pitching, and the game lasted a blazing one hour and 41 minutes.

Please keep in mind our Purple Row Community Guidelines when youre commenting. Thanks!

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Tracing the Constant Evolution of Tom Ford – InsideHook

Posted: at 11:31 pm

We live in an age with a steadily decreasing number of polymaths. Its difficult enough to be skilled and learned in one particular art form or discipline; having multiple high-level talents is even more of a challenge. Yet the career of Tom Ford has demonstrated how seemingly disparate areas of focus can converge in one persons life. Ford made his name as a fashion designer, but has branched out into more and more areas over the years everything from a line of watches to directing acclaimed films.

This month brings with it the publication of Tom Ford 002, a new book documenting his work since 2005. Air Mail recently published the books introduction, which was written by Graydon Carter who did the same for Fords first book and offers an inside look into what its like to spend time with Tom Ford.

Carter covers a lot of ground here. Regarding Fords launch of the fashion brand Tom Ford, Carter observed, Im not sure whether [Ford] would call this a second act or a third act. Either way, its been a hell of a triumph.

But there are also more insightful moments, such as Carter addressing the nature of Fords professional success. People think success is a giant wave of blithe happiness, Carter wrote. In Toms case, its that, certainly but its also the result of an almost otherworldly attention to details big and small.

Its a theme that Carter returns to again and again over the course of his introduction while also giving a sense of Fords own aesthetic choices in different aspects of his life. Its a fascinating look at a singular polymath.

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Utah’s Offensive Evolution Thrives From Beyond The Arc | Utah Jazz – UtahJazz.com

Posted: at 11:31 pm

"We made a shot."

Those were head coach Quin Snyder's parting words following Utah's 110-98 victory over visiting Atlanta on Tuesday night.

Although the words were said to evoke laughter which they did there was also a smattering of truth and respectful sarcasm to his statement.

Just hours before Snyder walked out of that presser with a smile on his face, he sat in the same chair and answered the same questions he's been asked for weeks from media members regarding the state of Utah's offense.

Perennially one of the top three-point shooting teams in the league, the Jazz had gotten off to a shockingly slow start this year. Utah was sitting at 26th in the league, shooting the deep ball at 31.8% nearly seven percentage points lower than last season.

But in the face of all those questions before tipoff, the customarily reserved Snyder opened up about his thoughts of Utah's offense.

"I understand the responsibility to write about the narrative of our three-point shooting," Snyder said pregame. "I don't think there's anyone on our team that redid their shot over the summer. So I would expect, at least on some level, that we start making more shots."

Rather than ending the conversation there, Snyder took it a step further as to why he wasn't concerned about when Utah's shots were going to start falling.

"To me, what's an interesting story, our offense is ranked No. 2 in the league," he added. "If you gave me what would probably be a three-point percentage in the bottom five last year and a No. 2 offense, I'd probably take the No. 2 offense with poor shooting."

As if fulfilling a prophecy, the Jazz had one of their best shootings night of the season against the Hawks on Tuesday night.

Utah shot 39.5% (15-for-38) from beyond the arc, their second-best percentage on the year. Six different players knocked down a three-pointer, with four of them knocking down at least two.

"It gives you life," Donovan Mitchell (27 points, 5-for-11 from deep) said postgame about the team finally knocking down some shots.

Following the victory over the Hawks, Utah currently has the No. 2 offensive team in the league. They scored 122 points per 100 possessions against Atlanta, putting them 0.1 away from the top spot.

"I want to be bold how we play. ... We got a lot of guys that can make shots," Snyder said. "We have a guy that got 49 (points) last year against Denver with a couple guys out. I don't know where you'd rank Bojan (Bogdanovic) on the scoring ladder, but we've got a lot of guys that can be a leading scorer on a different night."

Utah's ascension up the three-point ladder began to take shape in 2017 when Mitchell and Royce O'Neale joined the team. They made an immediate impact, both shooting 34% or better from beyond the arc.

But the actual percentage change came in 2019 when Utah added Bogdanovic, Mike Conley, and Jordan Clarkson, each shooting above 36% from three-point territory.

That change in 2019 allowed the Jazz to climb the rankings and finish that season as the NBA's top three-point shooting team, jumping from No. 12 to No. 1. Utah continued its torrid shooting last year, finishing fourth in three-point percentage the only team to rank in the top-five from the past two seasons.

With expectations set high this year, Snyder and the Jazz aren't backing down from them. They're finding ways to continue to push the envelope and keep Utah as the most efficient team in the league.

"Our focus will continue to be ways to get incrementally better. We'll continue to try to prepare for the shots that we're going to get for something that's been a big part of what we do," Snyder said.

But ever the perfectionist, Snyder wasn't willing to concede Tuesday night's performance as the big breakthrough fans were hoping for. Instead, he ended his press conference with six words that will keep the fire burning for the players when it comes to making shots.

"Not as many as they (Atlanta) did."

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More evidence of an evolutionary ‘arms race’ between genes and selfish genetic elements – University of Rochester

Posted: at 11:31 pm

November 11, 2021

The human genome is littered with selfish genetic elements, which do not seem to benefit their hosts, but instead seek only to propagate themselves.

These parasites of the genome can wreak havoc at the cellular level by distorting sex ratios or causing harmful mutations, and can even lead to a species extinction. But, as researchers at the University of Rochester report, species evolve mechanisms to fight back.

In a new paper published in Nature Ecology and Evolution, Daven Presgraves, a University Deans Professor in the Department of Biology at the University of Rochester, and Christina Muirhead, a computational biologist and population geneticist in Presgravess lab and the first author on the paper, present further evidence of an evolutionary arms race within organismsand the mechanisms at play in this arms raceto combat selfish genetic elements.

We have found that an evolutionary arms race has led to a proliferation of meiotic drive genes on the X chromosome and suppressor genes elsewhere in the genome, Muirhead says.

The researchers studied the genomes of three closely related species of Drosophila (fruit flies). Fruit flies share about 70 percent of the same genes that cause human diseases and are similar to humans on the molecular level. Because fruit flies have such short reproductive cyclesless than two weeksscientists can create generations of the flies in a short time. These key characteristics make the insects ideal models for learning more about human genetics.

The researchers discovered that each of the species of fruit flies they studied has 5 to 12 meiotic drive genes on the X chromosomes. The meiotic drive genesa type of selfish genetic elementcheat by getting into more than the typical 50 percent of offspring in the next generation. This allows the genes themselves to spread rapidly through a population.

The meiotic drive genes that the researchers studied are related to a meiotic drive gene called Doxdistorter on the Xwhich is found on the X chromosome and kills Y chromosome-bearing sperm. The researchers called their newly discovered genes Dox-like, or Dxl for short. The Dxl genes produce a protein called a histone that disrupts normal DNA packaging in Y-bearing spermatidsimmature male sex cellsleading to sperm death. Killing Y-bearing sperm means that subsequent generations will have mostly daughters and few sons.

The Dxl genes work only to propagate themselves, however, and dont realize that this may lead them on a path that could eventually take their host speciesand themselvesto extinction.

The drive genes get an evolutionary advantage by killing Y-bearing sperm, Presgraves says. But the individuals carrying the drive genes suffer reduced fertility, and the population becomes increasingly female-biased, risking eventual extinction.

Dxl genes skew sex ratios to increase the rate at which they get passed on, but the researchers uncovered another surprising dynamic. The species of Drosophila they studied have evolved a defense against the selfish genetic elements. This defense comes in the form of genes that are duplicates of the Dxl genes, but with an important modification. Much like the mythical Trojan Horse, the duplicate genes masquerade as Dxl genes, but contain a stealthy weapon. Instead of expressing Dxl proteins, the genes express small RNAs that silence the Dxl genes via RNA interference.

The research is further evidence that microscopic evolutionary arms races are taking place within organisms: selfish genetic elements evolve to benefit themselves, and the rest of the genome evolves suppressors to quell them. The selfish genetic elements then evolve to overcome the suppressor, the suppressor has to evolve to keep pace, and so on.Similar repetitive gene copies like the Dxl genes that selfishly bias sex ratios are common to the X and Y chromosomes of great apes and humans, Presgraves says. These are just one line of evidence that evolutionary arms races have important consequences for genome evolution.

Evolutions new era

Selfish genetic elements were dismissed as anomalies when they were first described nearly a century ago. Now, Rochester biologists are exploring the roles the elements play in inheritance, aging, speciation, and evolution.

What makes a species different?

Rochester research points to the presence of selfish genes, whose flow among species may dictate whether two species converge or diverge.

Tags: Arts and Sciences, Daven Presgraves, Department of Biology, research finding

Category: Science & Technology

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America’s Cup: Evolution rather than revolution will define new protocol – Stuff.co.nz

Posted: at 11:31 pm

Fiona Goodall/Getty Images

Team New Zealand and Britannia will be looking to build on the success of the foiling AC75s in the next America's Cup.

Expect evolution rather than revolution when the new protocol for the next Americas Cup is released on Wednesday.

Having missed the deadline to announce the venue for the 37th edition of the famous regatta, defender Team New Zealand and Sir Ben Ainslie's challenger of record Britannia, wont want to miss the deadline for the release of the key document they have been thrashing out for the last eight months.

Its a vital piece of paperwork that lays down the rules and parameters and comes with the competition well positioned for a much-needed period of consolidation.

INEOS Britannia

World champions Mercedes come on board for AC37

After years of design switches that included ushering in the foiling era to sports oldest trophy, there is an agreement to remain with the radical AC75 monohulls for the next two editions.

READ MORE:* The U-turn that led Tom Saunders to world Laser title* America's Cup: The genius behind Team NZ signing Nathan Outteridge* America's Cup teams forced to open doors* America's Cup: Little logic as New York throw their toys out of the cot

The boats captured the imagination of the sailors and the public for their debut in Auckland last summer and continuity is a key for the Cup to prosper.

Thats why the protocol will be more about refinement than reinvention.

After having just four teams involved last time, there is a real need to encourage new syndicates. Prospective outfits have been waiting on the details in this vast document before committing to a costly challenge for the Auld Mug.

Dave Rowland/Getty Images

Team New Zealand will outline the rules for their defence of the America's Cup.

It will be fascinating to see how they interpret the protocol and who decides to jump on board for yachting's wildest ride.

Some of the big moves in the protocol have already been signalled - the retention of the class with a limit of one new boat in this cycle; tougher nationality rules to limit crew poaching; separate youth and womens regattas to be run in conjunction with the main event; these will be sailed in new 40-foot foiling monohulls that can also be used for testing and development.

Dont expect the venue to be revealed on Wednesday, nor the specific dates for the challenger series or the America's Cup match. There is likely to be a broad time frame indicated for these to be confirmed in.

Look for a more streamlined administration of the Cup with one event authority handling it, hopefully reducing the tensions between the defender and challenger of record that increased as Auckland 2021 wore on.

With an eye on cost containment and allowing new teams to catch up, there could be restrictions over allowing existing teams to sail their current full-sized Cup boats during the next year.

The America's Cup knows it has a good product - an event steeped in history that is also at the cutting edge of sailing technology and the protocol will look to reflect and enhance that.

There is a need to maximises its profile better, especially after the restrictions the global Covid pandemic wiped out build-up regattas last time.

Expect that to be rectified in this cycle as sponsors and billionaire backers look for more bang for their bucks with increased exposure.

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Candyman Icon Tony Todd On Fantastic Way The Franchise Has Evolved – CinemaBlend

Posted: at 11:31 pm

Having kicked off the horror franchise, it was nice for OG fans to see the original Candyman Tony Todd pop up in the reboot. Making him a part of the reboot tied both stories together in many ways. Todd haunted the minds of horror fans for decades especially when repeating the characters name. The sequel expanded on the original themes with a 2021 lens. After taking part in said sequel, the horror icon gave his thoughts on the franchises evolution since the original film premiered three decades ago.

Keeping the spirit of the original Candyman grounded the reboot with Tony Todds finale message. After initially not part of the sequel, Todd eventually hopped aboard. It seemed like he enjoyed his time on the film and how it turned out. The original film touched on some heavy themes, which director Nia DaCosta expounded on in the reboot. The Candyman icon gave Gizmodo his thoughts DaCosta evolving the series with her installment.

Well, I think its summed up in Nia DaCostas brilliant interpretation and Colman Domingos line that Candyman is not a he, Candymans the whole damn hive. And I think thats the newest [take], that its not an isolated incident of only one Black man being unfairly ridiculed and tortured and lynched and vilified, castigated. It can happen to anybody, it doesnt have to be an African American. It can be any person that is ostracized and struck down before theyre able to reach their full potential, whether it be artistically, intellectually, or whatever. And I think thats fantastic.

Nia DaCosta got the seal of approval from Tony Todd, and thats what matters. Thankfully, Todd agreed with DaCosta taking certain themes and making them universal. It allowed Candyman to evolve from a vengeful figure to a symbol of the marginalized. Despite only popping up at the end, Todd wasnt too hung up on screen time and more about the vision.

Well, I was trained that there is no such thing as a small moment. Whatever moment you have, [make it] have a hammer-like impact. So I was shooting something else in South Africa and I got a call from Jordan. We talked at length and he explained his vision to me, and I totally agreed with it.

Of course, it was Jordan Peeles idea to have Todd pop up at the end. As Tony Todd put it, the final moment left an impact on moviegoers given the films reception. Todds moment brought all the plotlines together after teasing the horror icon the entire film. So, Candyman served his purpose in the bigger vision.

Hopefully, the reboots success will lead to more Candyman and Tony Todd in the coming years. While fans wait on sequel news, they can watch Candyman on Prime Video.

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Candyman Icon Tony Todd On Fantastic Way The Franchise Has Evolved - CinemaBlend

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