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Monthly Archives: March 2021
Applied Therapeutics to Host Virtual Rare Disease Forum – GlobeNewswire
Posted: March 21, 2021 at 4:36 pm
NEW YORK, March 16, 2021 (GLOBE NEWSWIRE) -- Applied Therapeutics, Inc. (Nasdaq: APLT), a clinical-stage biopharmaceutical company developing a pipeline of novel drug candidates against validated molecular targets in indications of high unmet medical need, today announced it will host a Virtual Rare Disease Forum on Tuesday, March 23rd, 2021 from 1:00pm to 3:00pm ET. The event will highlight Applied Therapeutics development programs in Galactosemia, SORD Deficiency, and PMM2-CDG. The agenda for the event will include:
Were excited to host this event to spotlight our clinical development programs in Galactosemia, SORD and PMM2-CDG, saidShoshana Shendelman, PhD, Founder, CEO and Chair of the Board of Applied Therapeutics. We believe that AT-007 represents an important advancement for patients with these rare diseases, and our clinical development programs offer a unique opportunity to meaningfully impact patients lives.
An audio webcast of the presentation will be available live. More details will be available at http://ir.appliedtherapeutics.com leading up to the event. An archived version of the presentation will be available following the event.
AboutApplied TherapeuticsApplied Therapeuticsis a clinical-stage biopharmaceutical company developing a pipeline of novel drug candidates against validated molecular targets in indications of high unmet medical need. The Companys lead drug candidate, AT-007, is a novel central nervous system penetrant aldose reductase inhibitor (ARI) for the treatment of Galactosemia, a rare pediatric metabolic disease. The Company initiated a pivotal Phase 1/2 clinical trial inJune 2019, read out positive top-line biomarker data in adult Galactosemia patients inJanuary 2020and announced full data from the trial inApril 2020. A pediatric Galactosemia study commenced inJune 2020. The Company is also developing AT-001, a novel potent ARI that is being developed for the treatment of Diabetic Cardiomyopathy, or DbCM, a fatal fibrosis of the heart. The Company initiated a Phase 3 registrational study in DbCM inSeptember 2019. The preclinical pipeline also includes AT-003, an ARI designed to cross through the back of the eye when dosed orally, for the treatment of diabetic retinopathy, as well as novel dual PI3k inhibitors in preclinical development for orphan oncology indications.
To learn more, please visit http://www.appliedtherapeutics.com and follow the company on Twitter @Applied_Tx.
Investors:Maeve Conneighton(212) 600-1902 orappliedtherapeutics@argotpartners.com
Media:media@appliedtherapeutics.com
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Freedom of hate and destruction: Downtown businesses sound off on violence – KOIN.com
Posted: at 4:36 pm
Mayor Wheeler echoes concerns of local businesses losing money
by: KOIN 6 News Staff
Destruction to Pearl District businesses on March 13, 2021 in the Pearl District (PPB)
PORTLAND, Ore. (KOIN) Some business owners in downtown Portlands Pearl District are pleading for an end to continued property damage and violence surrounding their stores.
Two small business ownersboth of whom requested to maintain anonymitytold the Portland City Council Wednesday the financial damage has been overwhelming. They added the vandalism does nothing for social justice.
We all know this isnt freedom of speech, said a woman named Lisa who owns a small business in the Pearl District. This is pure freedom of hate and destruction. We, small business owners, are not wealthy people. We do not have an instant ATM from which we can repeatedly take money out to pay to have plywood boards put up then taken down, remove graffiti, replace broken glass doors, glass windows, et cetera.
Portland Mayor Ted Wheeler echoed the frustration and anger of business owners. He said the local retailers and restaurants were the ones being hurt, not the faceless large corporations.
On Friday, March 12, 13 people were arrested and roughly 100 in total were detained after a march ended in widespread vandalism and criminal activity. Some in the group had smashed windows to several businesses leading officers to create a perimeter around the crowd.
Some of the protesters also confronted the police, throwing rocks and full cans of beer, according to PPB. Officers reported using pepper spray. Two of the 13 people arrested were suspects carrying firearms, wearing body armor and helmets, according to police.
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Freedom of hate and destruction: Downtown businesses sound off on violence - KOIN.com
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Can-Fite BioPharma Interview to Air on Bloomberg Television U.S. on the RedChip Money Report – Business Wire
Posted: at 4:36 pm
PETACH TIKVA, Israel--(BUSINESS WIRE)--Can-Fite BioPharma Ltd. (NYSE American: CANF) (TASE: CFBI), a biotechnology company advancing a pipeline of proprietary small molecule drugs that address inflammatory, cancer and liver diseases, today announced an interview with CEO Dr. Pnina Fishman will air on The RedChip Money Report on the Bloomberg Network in the U.S. on Saturday, March 20th, at 7 p.m. local time in 73M homes across the United States. The RedChip Money Report also airs on Bloomberg International in Europe in 100M homes at 6 pm local time on Sundays.
In the exclusive interview, Dr. Fishman discusses the Companys upcoming milestones, updates on the pipeline of proprietary small molecule drugs addressing inflammatory, cancer and liver diseases.
To view the interview segment, please visit: https://youtu.be/T6ccv539s4I
The RedChip Money Report" delivers insightful commentary on small-cap investing, interviews with Wall Street analysts, financial book reviews, as well as featured interviews with executives of public companies.
About Piclidenoson
Piclidenoson is a novel, first-in-class, A3 adenosine receptor agonist (A3AR) small molecule, orally bioavailable drug with a favorable therapeutic index demonstrated in Phase II clinical studies. It is currently being evaluated in a multinational Phase III study as a treatment for moderate to severe psoriasis and a Phase II U.S. study for the treatment of moderate to severe COVID-19.
About Namodenoson
Namodenoson is a small orally bioavailable drug that binds with high affinity and selectivity to the A3 adenosine receptor (A3AR). Namodenoson was evaluated in Phase II trials for two indications, as a second line treatment for hepatocellular carcinoma, and as a treatment for non-alcoholic fatty liver disease (NAFLD) and non-alcoholic steatohepatitis (NASH). A3AR is highly expressed in diseased cells whereas low expression is found in normal cells. This differential effect accounts for the excellent safety profile of the drug.
About Can-Fite BioPharma Ltd.
Can-Fite BioPharma Ltd. (NYSE American: CANF) (TASE: CFBI) is an advanced clinical stage drug development Company with a platform technology that is designed to address multi-billion dollar markets in the treatment of cancer, liver, inflammatory disease and COVID-19. The Company's lead drug candidate, Piclidenoson, is currently in a Phase III trial for psoriasis and a Phase II study in the treatment of moderate COVID-19. Can-Fite's liver drug, Namodenoson, is headed into a Phase III trial for hepatocellular carcinoma (HCC), the most common form of liver cancer, and successfully achieved its primary endpoint in a Phase II trial for the treatment of non-alcoholic steatohepatitis (NASH). Namodenoson has been granted Orphan Drug Designation in the U.S. and Europe and Fast Track Designation as a second line treatment for HCC by the U.S. Food and Drug Administration. Namodenoson has also shown proof of concept to potentially treat other cancers including colon, prostate, and melanoma. CF602, the Company's third drug candidate, has shown efficacy in the treatment of erectile dysfunction. These drugs have an excellent safety profile with experience in over 1,500 patients in clinical studies to date. For more information please visit: http://www.can-fite.com.
Forward-Looking Statements
This press release may contain forward-looking statements, about Can-Fites expectations, beliefs or intentions regarding, among other things, market risks and uncertainties, its product development efforts, business, financial condition, results of operations, strategies or prospects. In addition, from time to time, Can-Fite or its representatives have made or may make forward-looking statements, orally or in writing. Forward-looking statements can be identified by the use of forward-looking words such as believe, expect, intend, plan, may, should or anticipate or their negatives or other variations of these words or other comparable words or by the fact that these statements do not relate strictly to historical or current matters. These forward-looking statements may be included in, but are not limited to, various filings made by Can-Fite with the U.S. Securities and Exchange Commission, press releases or oral statements made by or with the approval of one of Can-Fites authorized executive officers. Forward-looking statements relate to anticipated or expected events, activities, trends or results as of the date they are made. Because forward-looking statements relate to matters that have not yet occurred, these statements are inherently subject to risks and uncertainties that could cause Can-Fites actual results to differ materially from any future results expressed or implied by the forward-looking statements. Many factors could cause Can-Fites actual activities or results to differ materially from the activities and results anticipated in such forward-looking statements. Factors that could cause our actual results to differ materially from those expressed or implied in such forward-looking statements include, but are not limited to: our history of losses and needs for additional capital to fund our operations and our inability to obtain additional capital on acceptable terms, or at all; uncertainties of cash flows and inability to meet working capital needs; the impact of the COVID-19 pandemic; the initiation, timing, progress and results of our preclinical studies, clinical trials and other product candidate development efforts; our ability to advance our product candidates into clinical trials or to successfully complete our preclinical studies or clinical trials; our receipt of regulatory approvals for our product candidates, and the timing of other regulatory filings and approvals; the clinical development, commercialization and market acceptance of our product candidates; our ability to establish and maintain strategic partnerships and other corporate collaborations; the implementation of our business model and strategic plans for our business and product candidates; the scope of protection we are able to establish and maintain for intellectual property rights covering our product candidates and our ability to operate our business without infringing the intellectual property rights of others; competitive companies, technologies and our industry; statements as to the impact of the political and security situation in Israel on our business; and risks and other risk factors detailed in Can-Fites filings with the SEC and in its periodic filings with the TASE. In addition, Can-Fite operates in an industry sector where securities values are highly volatile and may be influenced by economic and other factors beyond its control. Can-Fite does not undertake any obligation to publicly update these forward-looking statements, whether as a result of new information, future events or otherwise.
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Pokin Around: A visit from an old friend cycling the Mother Road to collect COVID stories – News-Leader
Posted: at 4:36 pm
Mike Comerford is one of those people you meet in life that you never forget andhope that fortune is kind enough that you'll meet again.
Prior to this week, I had last seen him in 1987. That's when he jumped at the chance to take a road trip to Warwick, New York to of all things help me and my wife move there.
I had taken a new job at a bigger paper. Mike and I had worked together at the daily paper in Elgin, Illinois.
Back then, he says, he was 6-foot-5. He's lost an inch to age. He's 62.
Mike Comerford, 62, worked with News-Leader columnist Steve Pokin in the newsroom of the Elgin (Illinois) Courier-News. The paper no longer exists. They had not seen each other since 1987 until this week. Comerford is biking Route 66 to Los Angeles as he collects COVID-19 stories.(Photo: Steve Pokin/News-Leader)
Back then, I had dark hair. I'm 67.
Our lives have taken different paths, but the bedrock of our friendship has remained true. After all these years, we're both still writing.
Mike is riding a bicycle that he estimates to be 40 to 50 years old along Route 66. He started in Chicago in late February and is headed to Los Angeles.
Along the way, he collects COVID-19 stories from everydaypeople he meets.
More: Pokin Around: Sheriff says same wayward cattle a regular problem; called in some 'cowboys'
Mike has interview subjects sign a release and asks them a few questions and videotapes their answers for some five minutes.
In this project, I am finding people incredibly articulate. You can not make up about how articulate people are about their lives. They start out by saying, I have nothing to say. And then, before you know it, they have these beautiful stories heartbreaking, exuberant, compelling and emotional.
"... I'm capturing the unique stories of people living with COVID, as opposed to all the obituaries."
With thunder, lightning and rain in the forecast, Mike Comerford leaves my driveway Wednesday morning en route to Los Angeles along Route 66. He is collecting stories from everyday people about COVID-19 and the pandemic. He hopes to make them into a book.(Photo: Steve Pokin/News-Leader)
I picked him up Tuesday at the Library Center on South Campbell. He spends much time in public libraries posting about his journey and, when needed, getting out of the weather.
The night before he stayed in a hotel in Seymour. He spends half his nights on the road in cheap hotels and the other half wrapped in a sleeping bag, in a small tent he pitches in a cemetery, park or forest preserve.
His odyssey is purely speculative. He will write a book. That's for sure. But the speculative part is whether it will make money.
Prior to this week, the last time News-Leader columnist Steve Pokin, left, saw Mike Comerford was in 1987. Pokin left the Courier-News in Elgin, Illinois, to take a job at a bigger paper in Middletown, N.Y. Comerford was quick to volunteer to help with the move and made the trip.(Photo: Steve Pokin/News-Leader)
He has no financial sponsor, but he is telling these stories with the help of the University of Florida'sSamuel Proctor Oral History Program. They liked the idea of a guy riding a bicycle on the Mother Road collecting pandemic stories.
After all, how often do we have a pandemic?
Mike told me about the interview he had earlier Tuesday with a woman he met on the Galloway Creek Trail, which is part of the Ozark Greenways.
The woman's name is Paula. She tells Mike she has had COVID-19 and has given it to several family members. She says: "If I were in charge I would unmask everybody. I know that sounds harsh; I would let people build up their immunities."
Mike Comerford spends much time at public libraries during his bicycle odyssey along Route 66 to Los Angeles. He often posts about his journey while on the road. He lives bare bones and often sleeps in parks and forest preserves and cemeteries.(Photo: Steve Pokin/News-Leader)
He has posted the remarkable interview on YouTube.
"I don't judge people," Mike tells me.
He simply lets them tell their stories and occasionally asks for clarification.
Mike's raw video is then dressed upwith spiffy graphics and music and posted by the University of Florida.
Go to YouTube and search for "thestorycycle and samuel proctor."
Mike has three younger sisters. His father was in the Navy and the family moved 10 times by the time he was 11, when they landed in Chicago.
He graduated in 1977 from St. Viator High School in Arlington Heights where, oddly enough, I once coached the track team for a season after stepping off the journalism career ladder to write a novel.
Mike started on the basketball team there and went on to Marquette, where he majored in political science.
He estimates he has visited close to 100 countries.
He worked at English-language papers in Moscow and Budapest.
More: Pokin Around: Love is never having to say I'm sorry I sank so much into my aging vehicle
He stayed at my house Tuesday night and offered these snippets of conversation:
"I'm sure there were guerillas in the area where I was at in the Philippines ...
"We were on the ZambeziRiveralong the border betweenZambiaandZimbabwe ...
"In Switzerland, I had accidentally run onto a restricted area used by the Swiss Army as a mortar range ..."
And he won the city heavyweight title in Cork, Ireland, where he attended college his junior year. He jabbed with his natural hand, his right, and sent them to sleep with his left.
I have no reason to doubt any of this.
After all, here was Exhibit A, in my living room: a 62-year-old journalist riding an old bicycle the 2,110 miles of Route 66.
But I did ask if he is physically up to the task.
If I take it in small steps," he says. "I am out of shape and older than I should be for such a project."
He takes his time and bikes 30 to 40 miles a day. Regarding his itinerary, he quotes Forrest Gump:
"When I got tired, I slept. When I got hungry, I ate. When I had to go, you know, I went."
In fact, Mike says, he is in the vanguard of what is called "slow journalism."
He asks if I know the exploits of journalist Paul Salopek, a National Geographic Fellow who has won Pulitzer Prizes for reporting on human genetics and the civil war in the Congo.
No, I say.
Salopek is retracing our ancestors' ancient migration on foot out of Africa and across the globe. His 24,000-mile, multiyear-voyagebegan in Ethiopia, believed to be our evolutionary "Eden." He started in January 2013 and his walk will end at the tipof South America.
It is called the "Out of Eden Walk" and Salopek is writing about it for National Geographic.
More: Pokin Around: When Captain Pink and the Larry Flynt circus came to Springfield
Mike has already completed one "slow journalism" project that resulted in his 2020 self-published book "American Oz: An Astonishing Year Inside Traveling Carnivals at State Fairs & Festivals."
Mike Comerford last year self-published "American Oz: An Astonishing Year Inside Traveling Carnivals at State Fairs & Festivals." He spent February 2013 to February 2014 hitchhiking as he worked as a carny from New York to California and Alaska to Mexico.(Photo: Steve Pokin/News-Leader)
From February 2013 to February 2014 he worked as a carny in 10 states from New York to California and up to Alaska.
In the book, which I've read, he captures the behind-the-scenes life of carnies and talks about the new face of American carnival workers who typically are from Mexico and work here on the same type of visa used by farm workers from Mexico.
The most amazing part of the book is Mike's trip to Tlapacoyan, Mexico. He went there during adrug cartel war between El Chapo's Sinaloa drug cartel and the Los Zetas drug cartel.
He had onlythe name of a fellow carny whom he had befriended.
Most men in Tlapacoyan come to the United States to work carnivals during the summer.
Mike took a 1,100-mile bus ride from Dallas to Veracruz, Mexico, which took 33 hours. He rode another bus six hours to Tlapacoyan and, incredibly, found his friend.
The book is available on Amazon.
Mike made some money on "American Oz."
"I know how to sell a book," he says.
He hopes to make some money on his current project.
I am attempting to make a living out of this. I want to be a book writer who writes a lot of books. If I wrote 20 books and all 20 of those books are making $1,000 then I will have a nice income. These are my first two projects.
Did you ever envision these "slow journalism" projects as a career?
"I never had a career vision for myself. I did want to travel and I did want to write.
His first inkling this could be a living came when he was hitchhiking through Canada.
"I met a French journalist in a van doing radio reports back to France. I saw this guy making a living doing whatever he wanted to do. And he was making a living by writing."
Mike is divorced and the love-of-his-life is his 15-year-old daughter Grace. He talks to her every day. She worries about him.
"She tells me not to eat badly. Or get run over by a car. Or get COVID."
At one point, he tells me, she suggested he hop a train to Los Angeles and just pretend like he rode his bicycle there.
On Wednesday morning, it is pouring rain in Springfield.
Mike is in my home packing his gear. He wraps his feet in cellophane to keep them warm. He tells me that not once in his life has ever felt cold in his sleeping bag and tent.
In my driveway, he takes his ancient bicycle from the back of my vehicle.
It thunders; there is lightning; Ron Hearst of KY3 warns of tornadoes.
I worry about Mike and offer him another night in Springfield.
No, he says. Time to get moving. Remember? Slow and steady.
Attached by bungee cordsis a sign on the back of his bicycle: "TELL ME A STORY. THE STORY BICYCLE. Check it on YouTube. TheStoryCycle@GMAIL.COM."
He swings his legonto his bike like John Wayne getting on a horse to face destiny.
Mike Comerford has always been an easy guy to talk to. He says people are more than willing to tell him about the impact of COVID on their lives as he videotapes them. While in Springfield, he interviewed a woman along the Ozarks Greenway who told him why she thinks masks are not needed.(Photo: Steve Pokin/News-Leader)
I say goodbye.
He looks at the ominous sky.
"The Mojave Desert," he says, "nowthat's gonna be tough."
Keep those questions coming. Send themto The Answer Man at 417-836-1253, spokin@gannett.com, on Twitter @stevepokinNL or by mail to 651 Boonville Ave., Springfield, MO 65806.
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Why lawsuits against the media may not hurt freedom of the press – The Conversation US
Posted: at 4:36 pm
Free speech advocates have long believed that suing a news organization threatens free speech. Democracy needs a press to be free to report, without fear or favor, the facts as it sees them.
But two recent legal actions against news organizations indicate that the First Amendment provides sufficient free speech protection, even when punishing lawsuits are filed against the press.
Falsehoods have flooded public discourse in recent years through outlets including talk radio, cable TV channels and social media such as Facebook, YouTube, Twitter, Reddit and Instagram. The proliferation of these falsehoods has seemingly normalized the practice of spreading lies.
Earlier this year Smartmatic, a little-known voter technology firm, sued cable channel Fox News for US$2.7 billion alleging defamation for baseless reports of fraud in the November 2020 election. One day later Fox News canceled Lou Dobbs Tonight, a program hosted by a staunch supporter of Donald Trump and repeater of his false assertions of voter fraud. Fox even broadcast fact-checking reports debunking its own anchors false claims about electoral fraud.
Smartmatic also threatened to sue another news outlet, Newsmax, for large sums unless it retracted defamatory statements that claimed Smartmatic software was used to change votes cast in the presidential election. Newsmax backpedaled by publishing the retraction that No evidence has been offered that Smartmatic used software or reprogrammed software that manipulated votes in the 2020 election.
So, does the fear of losing money in a lawsuit dictate what news organizations will report and what they wont?
No. As a former journalist and now scholar and practitioner of media law, I believe there are enough safeguards built into First Amendment jurisprudence to shut down liars and still protect robust debate of opposing viewpoints in America.
In a landmark First Amendment case almost 60 years ago, New York Times v. Sullivan, the U.S. Supreme Court decided that in the rush to gather and disseminate news, it is understandable that a news reporter may miss an important fact or interpret something wrong. Because preserving a free and robust exchange of ideas is vital to democracy, the court said it is worth the risk that some falsehoods may mistakenly be printed, and the press shouldnt be punished for it.
Thus, when a well-known person or company brings a defamation suit against a news organization, they must have a very strong case or they will lose. Defamation law heavily favors a media defendant.
To win, it is not enough to prove the news outlet published falsehoods, even if the plaintiff suffered significant damage to their reputation. Plaintiffs must prove the news organization published information even with the knowledge that [a statement made] was false or with reckless disregard for the truth.
Realistically, it means it is not worth suing a broadcaster or newspaper for defamation unless the lie is egregious, the damage to reputation is severe and the evidence of the news organizations intention or recklessness in publishing the story is practically undeniable.
That is a steep hill for plaintiffs to climb.
But courts draw the line when a news organization publishes untruths that could have been adequately checked for accuracy, but reporters or editors carelessly or knowingly shirked their duty to do so.
That is the linchpin of Smartmatics claim against Fox News. The lawsuit states Trump lawyers Rudolph Giuliani and Sidney Powell made the case for election fraud for weeks as frequent guests on Fox programs, but rather than fact-check those false claims, the lawsuit alleges, Fox joined the conspiracy to defame and disparage Smartmatic and its election technology and software.
When Giuliani and Powell were asked to produce actual evidence of voting fraud involving the company, none was forthcoming, but Fox published their claims anyway. And Smartmatic sent the network a letter before the lawsuit was filed asking it to issue a full and complete retraction of all false and defamatory statements and reports. In response, the network aired several times an interview with a voting technology expert who debunked the claims of fraud, but it is not clear whether a two-and-a-half-minute interview was enough to undo months of broadcasting inflammatory and baseless claims of election fraud.
Several legal experts believe Smartmatics lawsuit could be successful.
Free speech advocates may complain that disgruntled plaintiffs sometimes sue not because information reported about them is untrue, but rather to silence a news outlet that they know cannot afford to defend the lawsuit.
[Over 100,000 readers rely on The Conversations newsletter to understand the world. Sign up today.]
But there is a legal remedy for this, too. The District of Columbia and 30 states have laws, called anti-SLAPP statutes SLAPP stands for Strategic Lawsuit Against Public Participation that allow a defendant to get a case dismissed early in litigation and get paid attorneys fees and costs if the published speech is true and a plaintiff is suing just to silence the publisher.
It is an effective tool journalism organizations can use to defend themselves against bullying plaintiffs. Depending on the state, the effectiveness of anti-SLAPP statutes and who is allowed to assert them can vary.
Suing over illegal speech is a slow and expensive process. Nevertheless, defamation suits lodged against Fox News and threatened against Newsmax for false reports of fraud in the November 2020 election managed to quickly curtail misinformation spread by news networks, where years of excoriating criticism by public pressure campaigns and advertising boycotts did not.
It is enough to prompt First Amendment advocates to rethink whether defamation lawsuits may be a valuable tool to protect rather than a scourge that hinders the dissemination of free speech and truth in American discourse.
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Freedom fighter toils away without recognition – The Daily Star
Posted: at 4:35 pm
With cataracts in his eyes and difficulty in breathing, the frail 70-year-old man was toiling to bark logs with his axe in a sawmill of Domar upazila town.
Asked why he still has to work at this age, Nripendra Nath Roy alias Sinial said he has six mouths to feed and he cannot look away from them when they need him.
Likewise, when the country needed him 50 years ago, he took up arms and fought in different battles under Sector 6 until the country was free from the enemy.
As a means to honour the sons of the soil and to recognise their services for the country, the government has been disbursing monthly allowance for them every month.
However, valiant freedom fighter Nripendra, who fought in Burimari, Lalmonirhat and Nilphamari, has been deprived of the much-needed allowance due to a couple of callous errors made during the process of issuing his national identity (NID) card in 2008.
Not only his birth date was erroneously changed to 1960, instead of 1951, his alias, Sinial, was added next to his full name on the NID.
For the next seven years -- from 2008 to 2015 -- the elderly man tried in vain to get the error corrected despite spending countless hours during numerous visits at the Election Commission offices in Domar upazila and Nilphamari.
Ilius Hossain, former deputy commander of Muktijoddha Sangsad's Domar unit, said, "Nripendra Nath is a genuine freedom fighter as his name is included in the freedom fighters' list, compiled in India in 1971, which is accepted by all quarters. And this needs no further verification."
"My year of birth is 1951... My name is correctly mentioned as Nripendra Nath Roy in the Indian list, under serial number 37429," Nripendra said.
"But in the NID card prepared in 2008, the callous enumerators put down Sinial, my nickname, as part of my full name. On top of that, they entered my birth year as 1960, which is incorrect. These mistakes have had disastrous effects on my life," the war veteran said frustratingly.
In 2017, after the government launched a verification of the freedom fighters' list, Nripendra turned in necessary documents -- including a copy of the freedom fighters' list, compiled by Indian authorities in 1971, and recommendation letters from his co-fighters and from the committee tasked with the verification of freedom fighters' list in the upazila -- to Jatiya Muktijoddha Council (National Freedom Fighters' Council).
The Council, four years later, is yet to make a decision on the case of Nripendra, who was an active freedom fighter under the command of Capt Iqbal, sub-sector commander of Sector 6.
Domar unit Muktijoddha Sangsad's former commander Mohammad Nurunnabi said, "All of us consider him to be a real freedom fighter and he should get the recognition."
Contacted, Domar Upazila Nirbahi Officer Shahina Shabnam said, "We are considering the case with sincerity and we await the decision of Jatiya Muktijoddha Council."
Nripendra is originally from Chowki Bhajini village in Debiganj upazila of Panchagarh. He later became a permanent resident of his wife's native home at Pashchim Boragari Bagdokra village of Domar upazila in Nilphamari.
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Freedom fighter toils away without recognition - The Daily Star
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Family Express acquires six Freedom Oil stores, another station in McCordsville – The Times of Northwest Indiana
Posted: at 4:35 pm
Just after opening a new vintage ice cream parlor in a Crown Point strip mall, Dairy Belle will soon open its sixth location in Dyer.
The 71-year-old Region institution, which has been serving scoops since it started in Hammond in 1950, is opening next to Pop's on U.S. 30 in Dyer, about three miles west of its existing location on U.S. 30 in Schererville.
TheColao family, owner of Dairy Belle, is friends with Pop's owners, which led them to open next to Pop's Italian beef restaurants in Crown Point and now Dyer, Natalie Colao said.
The new ice cream parlor in Dyer will be around 1,800-square-feet with indoor seating, an outdoor patio and a drive-thru. It will be the first Dairy Belle to occupy a newly constructed location, and it will be open year-round.
"They're ready to break ground," Colao said. "Assuming everything goes as projected, it should be open mid-summer."
The goal is to have the ice cream shop open by mid-June, in the midst of the busy season.
Dairy Belle will serve familiar favorites like soft serve ice cream, Dole Whip pineapple, sundaes, malts, flurries, shakes and build-your-own banana splits.
"It will be the same menu as the other location," Natalie Colao said.
Both businesses could benefit from being so close to each other, Colao said. People could grab a dinner of Italian sausage, gyros or Reuben sandwiches at Pop's and then swing by Dairy Belle for dessert.
"We have lines down the street on U.S. 30," she said. "They do well at that Dyer location and get lines down the street on U.S. 30. We're not sure exactly what to expect. They might need to put in a stop light."
The new Dyer location should draw from a wide area, including south suburban Illinois and Munster.
"We've gotten questions from customers about whether it will take away from our Schererville location," she said. "But our Schererville location draws from Schererville, Merrillville and Hobart. This should attract more people from Dyer and St. John."
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2021 RoadTrek Play Camper Van Unleashes Freedom and Comfort Into the Wild – autoevolution
Posted: at 4:35 pm
The vehicle here is known as the 2021 Play from none other than Roadtrek. Dont know this team? Well, the brand has officially been around since 1980, but its conception began in 1974 when Jac Hanemaayer decided to create his own motorhome vehicles. In 2019, the Roadtrek brand was acquired by Groupe Rapido in order to continue producing vehicles like the Play.
To kick things off, the wonderyou see is built on a Ram ProMaster 3500 extended van chassis with an automatic 6-speed transmission. This 3.6-liter, V6, 24-valve engine cranks out 280 hp (283 PS) and 260 lb-ft (352 Nm) of torque @ 6400 RPM. Think you need any more to lug around the GCWR of 11,500 lb (5,216 kg)? Didn't think so.
An exterior length of 20.75 ft (6.32 m), width of 6.92 ft (2.11 m)), and height, with roof AC, of 9.42 ft (2.87 m), give way to an interior that allows for 6.2 ft (1.88 m) of headroom and filled with more than enough features to live life on the road until restrictions are lifted.
Waterworks are handled by a 37-gallon (140-liter) freshwater tank, a 14-gallon (53-liter) gray water tank, and finally an 8.5-gallon (32-liter) black water tank, will aid the needs for three permanent guests.
One thing that sets the Play apart from other vehicles in its class, is the lack of an excessive number of floorplans; only one option exists for this camper. Frankly, you dont need to offer your customers more than one floorplan if its versatile enough to match any needs that may arise during the journey.
The kitchen is equipped with more than the necessaryequipment needed to cook a five-star meal and includes a microwave oven, two-burner recessed propane stovetop, and sink with faucet. A flip-up counter extension, slide-out pantry, and large pot and pan drawer are sure to meet your meal-plan needs.
For sleeping, two twin beds can be found at the rear. These can be kept separate, for example, if traveling with a friend, or can be combined to form a king, if traveling with your partner. A king bed is usually suitable for up to three folks, but if you dont want to feel cramped, an optional feature transforms the two front seats into an extra single bed. The bathroom is a fully enclosed system with marine toilet, sink, and shower. Nothing too fancy, but inclusive of everything you need.
Several other features like a 12-volt macerator sewage pump and gravity dump, power inverter, 400 AGM battery system, and monitor panel for these features, is also found. Even though the manufacturers website shows only a couple of optional features, theyll probably be more than happy to work out whatever other needs you may have. Heck, for a $104,986 starting MSRP, they better be.
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2021 RoadTrek Play Camper Van Unleashes Freedom and Comfort Into the Wild - autoevolution
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Cell to Singularity Evolution Never Ends – Digit
Posted: March 20, 2021 at 3:22 am
Developed and published entirely by a single studio - Computer Lunch, Cell to Singularity is quite a unique game.This is quite an astoundingly ingenious way of blending genres and in fact, it is actually a good mix of gaming with education! The game contains textbook definitions from chemistry and biology and portrays how our cosmos began, and how life was developed.
This is how you make a game thats not only engaging but doesnt drive the player away because of the way the game is monetised. In fact, this particular balancing effect makes this game ridiculously addictive. Cell to Singularity - Evolution Never Ends is basically a clicker game in which you have to chart a rather accurate path of evolution of the human race right from the primordial soup, all the way to terraforming Mars. The visual presentation makes the game an interactive, animated and educational tutorial through the passage of time. The visuals make you feel like you are in-charge of the evolution process - interactive in the sense that the player plays the game and pushes the evolution forward through known paths to get to where we are now. There are research upgrades along the way which make your resource collection easier and the concept of resets allows you to get additional accelerators to speed up your progress even further. While you can buy your way through the game, theres also the option of watching ads to accelerate progress. This way, you can complete the entire game in under a week with ease. The developers make no attempts to hide the addictive nature of the game, its plastered all over the play store. Thankfully, the developers didnt make the grind excruciating as most clicker games tend to last way longer by means of the grind.
While its only recently been introduced to the Play Store, the game has been around on Steam for over a year and the developers seem to regularly add new content. Its basic 3D models, low rendering, no lighting and basic textures make this game one of the lowest-demanding games in terms of hardware. Even though the game offers premium currencies for standard prices, the in-game currency you earn should be enough to provide for everything you might need. Overall, this is how a games monetisation system ought to be designed, and we would recommend you give it a shot.
Publisher: Computer LunchDeveloper: Computer LunchPlatform: Android / iOSPrice: Free
While not dishing out lethal doses of sarcasm, this curious creature can often be found tinkering with tech, playing 'vidya' games or exploring the darkest corners of the Internets. #PCMasterRace https://www.linkedin.com/in/mithunmohandas/
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My Hero Academia: Will Izuku Become The Singularity? – ComicBook.com
Posted: at 3:22 am
Will Izuku Midoriya become My Hero Academia's dreaded Quirk Singularity? The question just became a big focus for fans; My Hero Academia's latest manga arc has been all about Izuku communing with One For All and its previous users, setting the stage for the young hero to finally unlock the power's full potential. However, we went a step further with an additional theory: Deku will use OFA's full power to pull the big twist of ultimately absorbing the power of All For One into himself. The question at that point is will Izuku become the Singularity? And what could he do with that power?
WARNING: My Hero Academia Manga SPOILERS Follow!
If you don't remember, the "Quirk Singularity" was a theory from All For One's mad scientist disciple, Dr. Garaki, first proposed seventy years before the events of My Hero Academia. Garaki theorized that each generation of quirk users would blend powers and breed a new generation of more powerful quirk powers and that eventually, that evolutionary increase in power would outpace the human body's ability to control it, resulting in a doomsday scenario when one insanely powerful quirk (or many) wiped society out.
We've already broken down why Izuku ultimately trying to absorb AFO is perfectly fitting with the foreshadows of the story and Deku's character arc. However, though Izuku would do that in the spirit of noble sacrifice, it could end up being a bigger burden than he's able to bear - and a bigger threat to the world than the villains were!
It wouldn't be shocking (at this point) if My Hero Academia's big final threat was Izuku struggling to hold both OFA and AFO in balance, without destroying the world in the process. It's also a suitable way to set up a final battle between All For One and his little brother (One For All's original user) to have their own final battle in the strange realm where the living consciousnesses of both powers exist. It would pretty much be the culmination of all the core storylines around the main character (Izuku Midoriya) and antagonist (Tomura Shigarak); Deku finally bringing the powers into balance would also explain why he's able to narrate My Hero Academia as the No. 1 hero. He would literally be god-level if he survives the singularity.
My Hero Academia releases new manga chapters FREE ONLINE weekly. Season 5 of the anime will premiere this year.
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My Hero Academia: Will Izuku Become The Singularity? - ComicBook.com
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