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Monthly Archives: March 2020
Scientist says anti-epilepsy drug can be repurposed for Covid-19, writes to ICMR to test it – ThePrint
Posted: March 31, 2020 at 5:55 am
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New Delhi:A leading scientist at the International Centre for Genetic Engineering and Biotechnology (ICGEB) in New Delhi has found that valproic acid, an anti-epilepsy drug, can be repurposed and used for acute cases of Covid-19.
The scientist, Neel Sarovar Bhavesh, has written to the director general of the Indian Council of Medical Research (ICMR), the apex body in the field, to test valproic acid at the National Institute of Virology in Pune or any ICMR lab to find a quick solution to the coronavirus crisis.
The ICGEB is part of the research consortium working to find a cure and vaccine for Covid-19.
Valproic acid is an approved drug, whose patent expired recently. It is sold under brand names such as Depacon and Stavzor to treat epilepsy. The University of California has also validated the ICGEBs research findings it lists valproic acid as one of the molecules for repurposing and testing for use against the Covid-19 virus.
Also read: AI identifies potential drugs and a DNA vaccine in the works latest on Covid-19
Bhavesh, the head of transcriptional regulation at ICGEB, told ThePrint: We have performed high-throughput virtual screening (HTVS) of 1.2 million small molecules from the four databases, and later performed Energy calculation and molecular binding simulation. We found that valproic acid CoA may be repurposed to inhibit the RNA-dependent RNA polymerase of the virus.
We have written to the DG ICMR to test this molecule on cell culture and animal testing facilities, in combination with potent binding blocking molecules. Currently no one in India outside the NIV and ICMR has access to the Covid-19 virus, Bhavesh said.
About 1,100 strains of the novel coronavirus have been sequenced from around the world. We (in India) have around 700 confirmed positive cases, but only two virus sequences are available at the NIV. These sequences are different from each other, he explained.
Bhavesh revealed that after the publication of the ICGEB research, multinational pharmaceutical company GlaxoSmithKline contacted them.
However, Bhavesh said theres an urgent need for cooperation from government bodies like the ICMR and the NIV in terms of giving researchers access to the virus strains in India to test on.
There should be synchronisation in testing and developing. If NIV or any another research institution finds success, lots of patients can be cured and saved. The need of the hour is to find the solution. The NIV must cooperate with other institutions more generously, he said.
A day before, Union Biotechnology Secretary Renu Swarup also said in an interview that early solutions for the novel coronavirus can be found from repurposed drugs, and that developing new drugs would take time.
Also read: Old drugs, new trials hopes pinned on HIV, malaria, ebola, TB vaccines to fight Covid-19
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Cannabis Compound CBD Acts as Helper to Boost Antibiotic Effectiveness – Genetic Engineering & Biotechnology News
Posted: at 5:55 am
Research by a University of Southern Denmark team has found that the cannabis compound cannabidiol (CBD) may act as a helper compound to boost the effectiveness of antibiotics against drug-resistant Gram-positive bacteria. A study headed by Janne Kudsk Klitgaard, PhD, associate professor, clinical microbiology, found that combining CBD with the antibiotic bacitracin (BAC) had a more powerful effect against bacteria including Staphylococcus aureus, than BAC alone. Based on these observations, the combination of CBD and BAC is suggested to be a putative novel treatment in clinical settings for treatment of infections with antibiotic-resistant Gram-positive bacteria, the researchers stated in their published paper in Scientific Reports, titled, Cannabidiol is an effective helper compound in combination with bacitracin to kill Gram-positive bacteria.
Since the discovery of penicillin by Sir Alexander Fleming in 1928, antibiotics have saved millions of lives from fatal infections worldwide, the authors wrote. However, over time, bacteria have developed mechanisms to escape the effects of one or more antibioticsmultidrug resistance (MDR)leading to an increasing global health threat. With fewer antibiotics available to treat MDR bacterial infections, the possibility of entering a pre-antibiotic era is looming ahead, the team stated.
Among alternative strategies that are being explored to help address antibiotic resistance, helper compounds, also known as antibiotic potentiators or resistant breakers, are gaining attention. Such helper compounds are non-antibiotic compounds that act as adjuvants for antibiotics, operating synergistically through mechanisms including efflux pump inhibition, enzyme inhibition, or changing membrane permeability, which can contribute to improving antibiotic efficacy.
Given that overuse of antibiotics is the main cause of antibiotic resistance, the combination of an antibiotic with a helper compound could reduce the amount of antibiotic needed to achieve bacterial growth inhibition or killing than if the antibiotic was used alone. This strategy may, therefore, decrease the likelihood of resistance development, and investigations to identify efficient helper compounds are thus important, the investigators suggested.
CBD, from the cannabis plant Cannabis sativa, acts as an antagonist of both the cannabinoid type 1 and 2 (CB1 and CB2) receptors, and has been shown to have anti-sedative, anti-psychotic, and anxiolytic effects, the team noted. The compound has also been linked with a variety of effects, including inhibiting cancer cell growth, neuroprotection in neurodegenerative diseases such as Parkinsons disease, and post-ischemia, and anti-inflammatory effects, as in type 1 diabetes.
CBD has also been observed to inhibit bacterial growth, but the use of cannabidiol as an antibiotic adjuvant hasnt yet been investigated, the team continued. Not much is known regarding antimicrobial effects of cannabinoids and even less on the mechanism of action the use of cannabidiol as an antibiotic adjuvant has not been studied so far.
For their reported study, the researchers evaluated whether CBD could act as a potential helper compound to increase the effectiveness of the antibiotic bacitracin, which is a mixture of cyclic peptides that interfere with the bacterial cell wall and interrupt biosynthesis of peptidoglycan, leading to cell lysis. The team first validated the antimicrobial effect of cannabidiol against the Gram-positive bacteria methicillin-resistant Staphylococcus aureus (MRSA), and also against Enterococcus faecalis, Listeria monocytogenes, and methicillin-resistant Staphylococcus epidermidis (MRSE). They then tested the effects of combining CBD and BAC against different Gram-positive bacteria, providing initial indication that CBD could potentiate the antimicrobial effects of the antibiotic.
Further tests with the combination of CBD and BAC against S. aureus showed that dual treatment caused morphological changes in the bacterial cells that affected cell division, so that the bacteria could no longer divide normally. the combination of CBD and BAC affects the cell envelope causing irregular cell division visualized by multiple septa formations and irregular cell membrane. These effects werent seen with either treatment on its own; CBD and BAC alone caused no morphological changes, they wrote.
The combined treatment was also found to decrease autolysis in S. aureus, while CBD was shown to cause depolarization of the cytoplasmic membrane. Gene expression analysis confirmed that treatment using CBD in combination with BAC resulted in reduced expression of key cell division and autolysis genes in the bacteria. The combination of BAC and CBD was, however, and as expected, not effective in Gram-negative bacteria. As a mixture of cyclic peptides that interrupt cell wall synthesis in Gram-positive bacteria, the antibiotic is probably unable to cross the outer membrane in Gram-negative bacteria, the researchers pointed out.
In this study, we found that the antibacterial effects of BAC against S. aureus as well as other Gram-positive bacteria can be enhanced by cannabidiol originating from the cannabis plant, the scientists concluded. They acknowledged that further work will be needed to understand the mechanisms of action of combined CBD and BAC treatment on Gram-positive bacteria. Changes observed in morphology were not caused by compositional changes in the cell wall muropeptide composition. Membrane potential changes for the combination of CBD and BAC compared to either CBD or BAC treatment alone did not reveal the mechanism of action for the combination of CBD and BAC, they wrote. Future studies are therefore focused on the cell division and cell envelope to identify the mechanism of action.
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Treatment gets five out of Intensive Care – Dominican Today
Posted: at 5:55 am
At least five patients, including some doctors, have overcome the critical state of health in which they had fallen due to the coronavirus and been moved from the Intensive Care units to normal hospital wards, after undergoing an expensive treatment that is producing good results.
Of the patients who have responded adequately to treatment, there are four from Santiago: Dr. Daniel Rivera, president of the Board of Directors of the Unin Mdica Clinic, urologist Fausto Hernndez, ex-governor Jos Izquierdo and patient Juan Ramn. In Santo Domingo, the political leader of San Pedro de Macors, Senator Jos Hazim, while Dr. Felix Antonio Cruz Jiminin has presented significant improvement, although he is still in intensive care with mechanical respiration, admitted to the General Hospital of the Plaza de health.
The details were offered by the Minister of Public Health, Rafael Snchez Crdenas, on the eighth day of the virtual press conference to report the updates to the Covid-19.He said it is a non-over-the-counter medicine that is applied intravenously and is applied to critically ill patients with complicated pneumonia.
A drug used in the treatment of arthritis patients has been applied to these patients.It is tocilizumab, a biological medicine, which is supplied through the High-Cost Medicines Program of the Ministry of Public Health.
Tocilizumab (Actemra) is a biologic medication approved to treat rheumatoid arthritis (RA) in adults, polyarticular juvenile rheumatoid arthritis (JRA), and the systemic form of juvenile idiopathic arthritis (JIA) in children. It isused to suppress the immune system in autoimmune diseases.
Biological drugs are artificial and manufactured using genetic engineering techniques and are closely related to a protein that the body produces naturally.
Dr. Snchez Crdenas reported that there are nine doctors registered with the virus, of whom four were in the process of their work, and others were infected on a cruise or airplane trip, and about three nurses.
He recalled that the highest risk of death is in people over 60 years old and people with co-morbidities, so he called people to take more extreme care of older adults.
Cross-testsThe Minister of Public Health, Rafael Snchez Crdenas, announced that from yesterday the trial would begin with cross-tests at the Dr. Defill National Laboratory, in order to speed up the confirmation of Covid-19 cases.
THE PROCESSSnchez Crdenas revealed that starting today, Saturday, rapid tests of up to 15 minutes will be made, through blood collection obtained from the pulpejo, with patients who have tested positive for other types of tests, to confirm their effectiveness, and then put them into service.
The testsThe effectiveness of rapid tests can be as high as 95%, and the PCR tests, which are being applied in the laboratory, are a specific test with 95% effectiveness, said Crdenas.Those 15-minute rapid tests, of which there are already samples in the country, will be tested today with patients.
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Treatment gets five out of Intensive Care - Dominican Today
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A Bioweapon Or Effects Of 5G? 7 Conspiracy Theories Around Coronavirus That Will Shock You – The Biggest Humanitarian Crisis – Economic Times
Posted: at 5:55 am
As conspiracy theories started spreading like wildfire on the Internet, several misguided rumours about the connection between 5G and coronavirus surfaced online. COVID-19, is believed to have originated from a wet market in Wuhan, China, in November. Coincidentally, China also turned on some of its 5G networks in November.
Rumours gained steam when Keri Hilson, popular American singer, with 4.2 million followers on Twitter, sent out tweets last week about the alleged connection between 5G and COVID-19, writing, "People have been trying to warn us about 5G for YEARS. Petitions, organizations, studies... what we're going through is the affects [sic] of radiation. 5G launched in CHINA. Nov 1, 2019. People dropped dead."
Several conspiracy theorists also alleged that the viral videos of people dropping on the ground and fainting in China, were a result of 5G radio waves messing with the oxygen levels in blood of the general public.
Soon, a UK based fact checking website, FullFact, debunked the claims and argued that there is no evidence that 5G is harmful to peoples health.
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Adapting from Home: This Weeks View of Video Meeting Triumphs and Concerns – Yahoo Finance
Posted: at 5:54 am
8x8.com/live Documents the Leading Trends in How People Around the World Are Using Video Meeting Technology to Teach, Heal, Work, and Socialize
8x8, Inc. (NYSE:EGHT), a leading integrated cloud communications platform, today announced its findings from an analysis of the social conversations about 8x8 Video Meetings and its related open-source project Jitsi.org use cases. Additionally, 8x8 reported that the global monthly active users of 8x8 Video Meetings is nearly 4.5 million, as people adopt video conferencing technology with unprecedented velocity. A livestream of these social conversations, daily updates on usage stats, and other video meetings and remote work resources are available at 8x8.com/live.
Video Conferencing and Meetings Notable Stats:
Five Trending Dynamics:
4.5 Million Video Meetings Monthly Active Users Globally; 1 Million Increase in Last 48 Hours
8x8 is the main contributor to the Jitsi.org open-source solution, and the standalone and integrated versions of 8x8 Video Meetings for business are based on it. The Jitsi.org code has been hardened with over a million downloads and in applications like banking video conferencing, education as a service platforms and home security applications globally. The product is packaged with 8x8 X Series for businesses that have a mobile and remote workforce requiring a highly reliable and resilient solution across desktop and mobile devices for voice, video, chat, contact center, APIs and advanced analytics. It is also available as a standalone offering and as part of 8x8 Express, which is for small organizations and teams that require a complete, preconfigured business phone system with a dedicated business number, video meetings and messaging in a single desktop and mobile application.
The free, standalone version of 8x8 Video Meetings, introduced to the public in November 2019, is available at https://8x8.vc, and includes international dial-in numbers in more than 55 countries. 8x8 Video Meetings utilizes the WebRTC standard which enables attendees to instantly join meetings without any downloads or plugins.
About 8x8, Inc.
8x8, Inc. (NYSE: EGHT) is transforming the future of business communications as a leading Software-as-a-Service provider of voice, video, chat, contact center, and enterprise-class API solutions powered by one global cloud communications platform. 8x8 empowers workforces worldwide to connect individuals and teams so they can collaborate faster and work smarter. Real-time business analytics and intelligence provide businesses unique insights across all interactions and channels so they can delight end-customers and accelerate their business. For additional information, visit http://www.8x8.com, or follow 8x8 on LinkedIn, Twitter and Facebook.
8x8 and 8x8 X Series are trademarks of 8x8, Inc.
View source version on businesswire.com: https://www.businesswire.com/news/home/20200327005088/en/
Contacts
8x8, Inc. Contacts:
Media: John Sun, 1-408-692-7054john.sun@8x8.com
Investor Relations: Victoria Hyde-Dunn, 1-669-333-5200victoria.hyde-dunn@8x8.com
The rest is here:
Adapting from Home: This Weeks View of Video Meeting Triumphs and Concerns - Yahoo Finance
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8 Best Zoom Alternatives for Video Conferencing and Webinars – Beebom
Posted: at 5:54 am
In the wake of Novel Coronavirus, remote working and video conferencing have become an essential part of both online and offline businesses. While Zoom is undoubtedly one of the best communication tools for real-time video conferencing, recently, many users complained about its subpar video quality and buffering issues. Its expected as companies all over the world are working online and putting a severe load on the servers. Then there was also the problem of Zoom secretly sending data to Facebook. So, whether you want better video conferencing or hate Zooms privacy policy, you can always use some capable alternatives. In this article, we have curated a list of 8 best Zoom alternatives which you should definitely try out in 2020.
I would say if you are looking for a complete web communication solution like Zoom then Microsoft Teams would arguably be the best alternative. It comes with a range of features and in some cases, even exceeds Zooms capabilities. You can chat, make a video call to your teammates, access Office 365 documents,collaborate in real-time, and also call anyone from Teams Calling or direct Phone System. As I said, its a powerful tool for web communication either through video, audio or chat.
However, keep in mind, Microsoft Teams allows you to host a web meeting of up to 250 participants in comparison to Zooms capability to scale up to 1000 participants. Nevertheless, Microsoft Teams can handle up to 10,000 teammates in a web seminar which is equal to Zooms ability. Having said all of that, Microsoft Teams brings a lot of additional perks like screen sharing, access to 1TB of OneDrive cloud storage, Office 365 access and more. To conclude, if you are looking for a capable Zoom alternative then Microsoft Teams is a suitable pick.
Visit Website (1-month Free Trial, Starts at $5/month)
I know Skype for Business has been replaced by Microsoft Teams and its no longer available. And thats why I am talking about the free version of Skype which is for personal users. Skype can be very helpful for small companies to hold web meetings and seminars in HD quality and best of all, without any charge. In terms of participant limit, Skype can host up to 50 participants which is half of Zooms 100 participants offering under the free tier plan. However, you do not have any limit on group calls on Skype whereas Zoom has a 40-min limit if there are more than 3 participants.
So in a way, Skype is not bad at all and brings limitless features without any cost. You can chat and call with your teammates as well, but if you want to directly call phone numbers across regions then you will have to pay some charges. But other than that, everything is free and accessible including call recording, mobile screen sharing, live subtitles and more. I would suggest, if you are using the Basic plan of Zoom then you should give a shot at Skype.
And if you are satisfied by Skypes free offering, you can also look at Skype alternatives to check out similar free video calling solutions.
Visit Website (Free)
Hangouts Meet is Googles new answer to Zoom and it seems the tech giant is finally into the race. At present, Hangouts Meet is only available to G Suite users and those who are enrolled in the G Suite for Education program. Now coming to features, its very much like Zoom in a sense, that you can just create a meeting and share the link with the participants. And they can easily join the meeting without creating any account whatsoever. And the best part is that, since its Google, you have dedicated apps for almost all the platforms so that is awesome.
Talking about the group limit, well, at this point, Hangouts Meet can host only up to 100 participants. However, Google recently announced that, from July 1, users will be able to create much larger meetings of up to 250 participants and can stream live webinars to 100,000 viewers. Thats great news, right? So, if you are looking for a Zoom alternative then Hangouts Meet is a decent pick right now. I would say, come July, Hangouts Meet will become a comparable rival to Zoom.
Visit Website (14-day Free Trial, Starts at $6/month)
If you are looking for a free alternative to Zoom then Jitsi Meet is the best option available. Its an open-source video conferencing platform where you can host group calls of as many users as you want and without any charge. On top of that, its encrypted, does not need an account, and there is no time limit as well. Thats awesome, but whats the catch? To be frank, there is no catch. Jitsi is fully funded by 88 company that uses Jitsis products like Virtual Office and other open-source projects.
In my brief usage, Jitsi Meet performed really well mainly because of its lightweight interface. You can just type the meeting name and hit enter to start the video conference. Further, you can set a password to your web conference or simply share the link to as many participants as you want. Surely, due to the Coronavirus outbreak, there has been a huge surge, but Jitsi still manages to pull through and you will get decent quality without much issue. Simply put, if you want a free solution to Zoom without compromising on security then Jitisi Meet is an apt choice.
Visit Website (Free)
You can consider Cisco Webex as another complete solution, similar to Zoom and Microsoft Teams. Its packed with features and caters mostly to corporations and large-scale companies. However, if you are a small company then you can take advantage of its free plan. It allows you to host a free Webex meeting with 100 participants and members dont need to create an account to join the meeting which is great. Similar to Zooms Basic Plan, you get HD video, screen sharing, and password-protected personal room.
However, Cisco Webex has a limit of 40 minutes just like Zoom so keep that in mind. If you opt for the paid plans then you can make group calls and host up to 200 participants. Apart from that, Cisco Webex offers Event Center for webinars, Training Center for online training, Support Center for remote support and more. Basically, you get everything as you would expect from a corporation-focussed video conferencing solution.
Visit Website (Free, Paid Plan Starts at $13.5/month)
Bluejeans is another great Zoom alternative that you can take a look at. Similar to Zoom, it offers video conferencing, personal rooms, events, and some really smart features. For instance, you can access Microsoft Teams Meetings from BlueJeans using its Cloud Video Interop technology. Thats really cool, right? Other than that, you can collaborate using audio and video using any device you have and in real-time. Having said all of that, the best part about BlueJeans is that it improves your productivity by highlighting meetings, creating transcription, automated alerts and a lot more.
I would say that you will have to use BlueJeans to understand how its much more than a video conferencing tool. As for the participant limit, it can host from 25 to 100 members which is quite good. Overall, if you want some smart management on your side then try out BlueJeans. Its quite comparable to Zoom on the UI/UX front.
Visit Website (Free Trial for 7 days, Starts at $9.99/month)
Zoho is quite popular for its online office suite and the company has been making some of the best tools for account management, word processing, and of course, web conferencing. Its basically a one-stop solution where you can schedule meetings, create documents, invite participants, and discuss the project all in real-time. Another best feature about Zoho Meeting is that its completely web-based. While apps offer you a broad range of features, you can still join calls and web conferences through a browser even without an app installed. Thats awesome, right? Apart from that, you get all the standard web communication features like screen sharing, audio calls, video conferencing and project collaboration. As for the limit, Zoho Meeting can host up to 100 participants at one time which is nowhere near Zoom, but if you have a small team then its pretty good.
Visit Website (Free Trial for 14 days, Starts at $10/month)
GoToMeeting is one of the oldest video conferencing platforms out there and its packed with features. The company primarily deals with corporate clients, but even if you are a small company then GoToMeeting has you covered. To begin with, you can host video and audio meetings from any device and from anywhere. And the best part is that GoToMeeting supports up to 250 participants for video conferencing and 1000 attendees for Webinars. Apart from that, GoToMeeting also brings direct call, cloud recording, Office 365 plugin for integrating all your Office documents, screen sharing and more. Overall, GoToMeeting is a complete web communication solution and you can reliably opt for it over Zoom.
Visit Website (Free Trial for 14 days, Starts at $12/month)
So those are our picks for the best Zoom alternatives that you can pick right now. As we went through the list, we can see that some companies offer a fully-featured video conferencing tool and some offer limited features. Nevertheless, based on your requirements and company size, you can pick a tool from the list. I am pretty sure, you wont be disappointed. Anyway, that is all from us. If we missed out on your favorite Zoom alternative then do let us know in the comment section below.
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8 Best Zoom Alternatives for Video Conferencing and Webinars - Beebom
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Test and trace with Apple and Google – TechCrunch
Posted: March 30, 2020 at 7:55 am
After the shutdown, the testing and tracing. Trace, test and treat is the mantra no lockdowns, no roadblocks and no restriction on movement in South Korea. To suppress and control the epidemic, countries must isolate, test, treat and trace, say WHO.
But what does tracing look like exactly? In Singapore, they use a TraceTogether app, which uses Bluetooth to track nearby phones (without location tracking), keeps local logs of those contacts, and only uploads them to the Ministry of Health when the user chooses/consents, presumably after a diagnosis, so those contacts can be alerted. Singapore plans to open-source the app.
In South Korea, the government texts people to let them know if they were in the vicinity of a diagnosed individual. The information conveyed can include the persons age, gender, and detailed location history. Subsequently, even more details may be made available:
In China, as you might expect, the surveillance is even more pervasive and draconian. Here, the pervasive apps Alipay and WeChat now include health codes green, yellow, or red set by the Chinese government, using opaque criteria. This health status is then used in hundreds of cities (and soon nationwide) to determine whether people are allowed to e.g. ride the subway, take a train, enter a building, or even exit a highway.
What about us, in the rich democratic world? Are we OK with the Chinese model? Of course not. The South Korean model? Probably not. The Singaporean model? Maybe. (I suspect it would fly in my homeland of Canada, for instance.) But the need to install a separate app, with TraceTogether or the directionally similar MIT project Safe Paths, is a problem. It works in a city-state like Singapore but will be much more problematic in a huge, politically divided nation like America. This will lead to inferior data blinded by both noncompliance and selection bias.
More generally, at what point does the urgent need for better data collide with the need to protect individual privacy and avoid enabling the tools for an aspiring, or existing, police state? And lets not kid ourselves; the pandemic increases, rather than diminishes, the authoritarian threat.
Maybe, like the UKs NHS, creators of new pandemic data infrastructures will promise Once the public health emergency situation has ended, data will either be destroyed or returned but not all organizations instill the required level of trust in their populace. This tension has provoked heated discussion around whether we should create new surveillance systems to help mitigate and control the pandemic.
This surprises me greatly. Wherever you may be on that spectrum, there is no sense whatsoever in creating a new surveillance system seeing as how multiple options already exist. We dont like to think about it, much, but the cold fact is that two groups of entities already collectively have essentially unfettered access to all our proximity (and location) data, as and when they choose to do so.
I refer of course to the major cell providers, and to Apple & Google. This was vividly illustrated by data company Tectonix in a viral visualization of the spread of Spring Break partygoers:
Needless to say, Apple and Google, purveyors of the OSes on all those phones, have essentially the same capability as and when they choose to exercise it. An open letter from technologists, epidemiologists & medical professionals calls on Apple, Google, and other mobile operating system vendors (the notion that any other vendors are remotely relevant is adorable) to provide an opt-in, privacy preserving OS feature to support contact tracing.
Theyre right. Android and iOS could, and should, add and roll out privacy-preserving, interoperable, TraceTogether-like functionality at the OS level (or Google Play Services level, to split fine technical hairs.) Granted, this means relying on corporate surveillance, which makes all of us feel uneasy. But at least it doesnt mean creating a whole new surveillance infrastructure. Furthermore, Apple and Google, especially compared to cellular providers, have a strong institutional history and focus on protecting privacy and limiting the remit of their surveillance.
(Dont believe me? Apples commitment to privacy has long been a competitive advantage. Google offers a thorough set of tools to let you control your data and privacy settings. I ask you: where is your cell service providers equivalent? Ah. Do you expect it to ever create one? I see. Would you also be interested in this fine, very lightly used Brooklyn Bridge I have on sale?)
Apple and Google are also much better suited to the task of preserving privacy by anonymizing data sets (I know, I know, but see below), or, better yet, preserving privacy via some form(s) of differential privacy and/or homomorphic encryption or even some kind of zero-knowledge cryptography, he handwaved wildly. And, on a practical level, theyre more able than a third-party app developer to ensure a background service like that stays active.
Obviously this should all be well and firmly regulated. But at the same time, we should remain cognizant of the fact that not every nation believes in such regulation. Building privacy deep into a contact-tracing system, to the maximum extent consonant with its efficacy, is especially important when we consider its potential usage in authoritarian nations who might demand the raw data. Anonymized location datasets admittedly tend to be something of an oxymoron, but authoritarians may still be technically stymied by the difficulty of deanonymization; and if individual privacy can be preserved even more securely than that via some elegant encryption scheme, so much the better.
Compared to the other alternatives government surveillance; the phone companies; or some new app, with all the concomitant friction and barriers to usage Apple and Google are by some distance the least objectionable option. Whats more, in the face of this global pandemic they could roll out their part of the test-and-trace solution to three billion users relatively quickly. If we need a pervasive pandemic surveillance system, then lets use one which (though we dont like to talk about it) already exists, in the least dangerous, most privacy-preserving way.
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Facebook, Google and Twitter Struggle to Handle Novembers Election – The New York Times
Posted: at 7:55 am
Mark Zuckerberg, Facebooks chief executive, ordered a lockdown for hundreds of employees late last year.
A lockdown is Facebook-speak for a period of intense, focused effort on a high-priority project. The workers, who included engineers and policy employees, were ordered to drop other projects and build tools to prevent interference in the 2020 election, said two people with knowledge of the instructions.
For Mr. Zuckerberg, who once delegated the messy business of politics to his lieutenants, Novembers election has become a personal fixation. In 2017, after the extent of Russias manipulation of the social network became clear, he vowed to prevent it from happening again.
We wont catch everyone immediately, but we can make it harder to try to interfere, he said.
Facebook has since required anyone running U.S. political ads to submit proof of an American mailing address, and included their ads in a publicly searchable database. It has invested billions to moderate content, drawn up new policies against misinformation and manipulated media, and hired tens of thousands of safety and security workers.
In the 2018 midterm elections, those efforts resulted in a relatively scandal-free Election Day. But 2020 is presenting different challenges.
Last year, lawmakers blasted Mr. Zuckerberg for refusing to fact-check Facebook posts or take down false ads placed by political candidates; he said it would be an affront to free speech. The laissez-faire approach has been embraced by some Republicans, including President Trump, but has made Facebook unpopular among Democrats and civil rights groups.
Still, Facebooks rank-and-file workers are cautiously optimistic. In late January, just before the Iowa caucuses, a group of employees gathered at the companys headquarters for a party to celebrate the end of the lockdown.
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Google Unveiled a Massive Stimulus Program of Its Own – Inc.
Posted: at 7:55 am
Google is one of the few companies that has an impact on almost all of our lives on a daily basis. It's where we go to find the best restaurants when we're traveling. It's where we search for local plumbers, or the closest hardware store, or where to buy vegetables to plant in a garden. That, of course, explains why more than half of all internet traffic originates with Google.
It also explains why Google is such a valuable place for small businesses to find new customers. The combination of organic searchand the paid ads associated with those searches has made it easy for businesses to target their audience based on meeting the exact things they're searching for. It's also made Google a massively profitable trillion-dollar company.
Now, in a blog post by Sundar Pichai, thecompany's CEO, Google says it will pitchin to help small businessesand other organizationsmake their way through the current health and economic challenge facing us all. That help comes in the form of an $800 million program that includes both direct financial assistance, as well as grants.
For small businesses, that means $340 million in credits for Google Ads that the company says can be used throughout 2020 across any of Google's advertising platforms. According to the company, the goal is "to alleviate some of the cost of staying in touch with their customers."
There's no signup or application process. Instead, credits will automatically be added to active Google Ads accounts.
In addition, Google says it is providing $250 million in ad credits to the World Health Organization (WHO), as well as other government health agencies that provide information about slowing the spread of Covid-19. Google had already said it would provide $25 million, but has significantly increased that amount with this announcement.
An additional $200 million will be provided to both NGOs and financial institutions "to help provide small businesses with access to capital." The company says it is focused on "people and communities underserved by mainstream financial institutions."
Lastly, Google is providing $20 million in Google Cloud services to researchers who are studying vaccines and treatment for Covid-19.
It's worth mentioning that Google is reportedly already seeing declines in advertising spending as businesses are forced to temporarily close down in communities across America. There's a chance that many of those businesses will struggle to reopen without help, which gives Google an incentive to help since those businesses are its customers. In addition, a credit is often an effective way to drive additional spending, which helps Google's bottom line at a time when it too could use a boost.
That's not to say that Google shouldn't get credit for these efforts. Google is in a unique position to actually help in a way that matters. Providing small businesses with the combination of advertising help as well as direct financial assistance in some cases could easily mean the difference between some businesses taking a short term hit or getting knocked out.
Preventing that is something we should all get on board with.
Published on: Mar 30, 2020
The opinions expressed here by Inc.com columnists are their own, not those of Inc.com.
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My top 3 Google Home pet peeves and how to fix them – CNET
Posted: at 7:55 am
Google Home is great, but it's not perfect -- some tasks require a workaround.
In the land of digital voice assistants, I love my Google Home ($99 at Walmart),I really do, but that doesn't mean our relationship is perfect. In fact, you could even say the honeymoon phase is pretty much over by now. I'm not saying we need counseling just yet, but my list of pet peeves has grown frustratingly long and it's starting to come across in my attitude when I talk to Google Assistant.
I know they say you should never expect anyone to change just for you, but that's one of the things I love most about Google Assistant --Google is constantly evolving the technology. So maybe I can hold out some hope that things will eventually get better.
Until then, here are my top three Google Home pet peeves what I do to work around them.
"Hey, Google" doesn't exactly roll off the tongue as easily as, say, "Alexa."
The problem: "OK, Google" just feels awkward and clumsy to me, and "Hey, Google" is no better. Don't even get me started on my frustration with Google being the name of the device (Google Home Mini), the AI (Google Assistant), the technology that powers the AI (Google search and services) and the company that owns it all (Google).
The fix: Even though Google won't let you choose a different wake word, you can manipulate Google Home's imperfect ear by using similar-sounding words to summon Google Assistant. "Hey, Boo Boo" remains my go-to, but I've also used "OK, Frugal," "Egg Noodle," "Go Lay Doo-Doo" and my all-time favorite "Cocaine Poodle."
The problem: You canset up a Google Home Routine to do just about anything, but the only way to trigger it is with a voice command. Alexa, on the other hand, lets youcraft location-based triggers, so when you leave the house, for example, Alexa can turn off all the lights, set the thermostat to "away" mode and play Mozart for your cats.
Google Assistant still cannot trigger a routine based on your location, even though Google always knows where you are if you're using Google Maps.
The fix: A good assistant should know whether I'm home or not and behave accordingly, so until Google implements location-based triggers I'm furtively using the Alexa app on my iPhone ($699 at Apple). Whether you have any Amazon Echo ($52 at Amazon) devices or not you candownload the Alexa app and set up location triggers on your Android phone or iPhone.
The problem: Even though phone-makers have all but eliminated the humble 3.5mm headphone jack from smartphones, Amazon Echo devices still have an audio output port for delivering audio to a more capable stereo system. Google Home devices have no such ports, which means the only way to connect them with an external audio source is with Bluetooth.
The fix: I hate to lean on Alexa again, but this works about as well (and for as little money) as anything: I picked up a couple of older second-genEcho Dots ($55 at Walmart) from Amazon Warehouse Deals, which I plugged into two sets of high-quality speakers. From there it's a breeze to connect your Google Home to the Echo Dot with Bluetooth.
Unlike any Google Home speakers, Amazon Echo has an AUX out port.
Just open the Google Home app and tap Settings > Device settings > Default music player > Enable pairing mode. From there, pair your Google speaker with your Amazon speaker to enjoy hi-fidelity sound from your stereo speakers.
Enough with the negativity -- Google Home is still my favorite smart home ecosystem because of the things it does well, likehelping you avoid touching surfaces in your house to slow the spread of germs andproviding accurate up-to-the-minute weather forecasts. And even though you can't connect them to an external stereo, you canpair multiple Google Home smart speakers into a stereo array, which improves their sound tremendously.
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