Monthly Archives: March 2020

Experts Assess Pandemic’s Damage to the Economy – New Ideal

Posted: March 31, 2020 at 6:01 am

The COVID-19 pandemic is having a negative impact on all aspects of human life, and the U.S. economy is no exception. The virus outbreak and governmental reactions to it have sent the stock market crashing and dealt a major economic blow.

In a special installment of our webinar series Philosophy for Living on Earth, the Ayn Rand Institutes chief philosophy officer, Onkar Ghate, sat down with finance and economics specialists Yaron Brook and Rob Tarr to talk about the effects of the virus and government intervention on the markets and the economy. The discussion covered many aspects of the ongoing financial crisis and approached the topic from a perspective informed by the philosophy of Objectivism.

Some of the questions covered in the discussion include:

Stay tuned for future installments of our webinar series, where we willcontinue to analyze the effects of the pandemic from the principled perspectiveof Ayn Rands philosophy. And please consider donating to ARI if you value ourunique and rational evaluation of this crisis.

Watch the full discussion between Ghate, Brook and Tarr, below.

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Yaron Brook Talks Ayn Rand’s ATLAS SHRUGGED, FOUNTAINHEAD & Covid-19 On Tom Needham’s SOUNDS OF FILM – Broadway World

Posted: at 6:01 am

Author Yaron Brook is Tom Needham's special guest this Thursday at 6 pm on WUSB's SOUNDS OF FILM. He will be discussing what one can learn from Ayn Rand's ATLAS SHRUGGED and FOUNTAINHEAD during the virus Crisis.

Yaron Brook is the host of the Yaron Brook Show, renowned best-selling author, and world class speaker. Brook's podcast can be heard on the Yaron Brook Show at BlogTalk Radio, Spreaker, Spotify and YouTube.

Brook was the Executive Director of The Ayn Rand Institute (ARI) for 17 years (2000-2017). He remains Chairman of the Board of ARI and its primary spokesperson.

Brook, an internationally sought speaker, travels extensively promoting Ayn Rand and her philosophy, objectivism.

THE SOUNDS OF FILM is the nation's longest running film and music themed radio show. For the past 30 years, the program has delivered a popular mix of interviews and music to listeners all over Long Island, parts of Connecticut and streaming live worldwide on the internet. Past people interviewed for the show include Rob Reiner, Alec Baldwin, Dionne Warwick, Chuck D, Alexander Payne, Michael Moore, William H. Macy, Billy Joel and Howard Shore.

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Yaron Brook Talks Ayn Rand's ATLAS SHRUGGED, FOUNTAINHEAD & Covid-19 On Tom Needham's SOUNDS OF FILM - Broadway World

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Sen. Rand Paul’s reply to why he risked exposing people, or Selfish is as selfish does – Louisville Eccentric Observer

Posted: at 6:01 am

We make fun of U.S. Sen. Rand Paul a lot. OK, more than a lot. Going waayy back.

But who deserves it more? Befitting his status as Kentuckys junior senator, only our senior senator Mitch McConnell suffers more scorn and bad-natured roasting from us at LEO.

Now, in The Time of Corona, Paul, a doctor and obstructionist of virus relief bills, gets a special poke with a hot stick for reportedly getting tested and going to the gym and consorting with colleagues before he got back the result.

And guess what?

He tested positive.

Paul released a statement this week defending his decision to not self-quarantine, saying he shouldnt have been tested at all. Whaat? Read this convoluted reasoning and let us know what kind of byzantine map of logic we would need to understand it.

Paul should have known better than to risk the health of other people. But we must understand that Rand Paul, who might as well have been named after the purposely selfish, libertarian, wack-job Ayn Rand, would be thinking about himself only.

Here is what he had to say:

Given that my wife and I had traveled extensively during the weeks prior to COVID-19 social distancing practices, and that I am at a higher risk for serious complications from the virus due to having part of my lung removed seven months ago, I took a COVID-19 test when I arrived in D.C. last Monday. I felt that it was highly unlikely that I was positive since I have had no symptoms of the illness, nor have I had contact with anyone who has either tested positive for the virus or been sick.

Since nearly every member of the U.S. Senate travels by plane across the country multiple times per week and attends lots of large gatherings, I believed my risk factor for exposure to the virus to be similar to that of my colleagues, especially since multiple congressional staffers on the Hill had already tested positive weeks ago.

As for my attendance at the Speed Art Museum fundraiser on March 7, unlike the other Kentucky government officials there, I had zero contact or proximity with either of the two individuals who later announced they were positive for COVID-19. The event was a large affair of hundreds of people spread throughout the museum.

There was an announcement by the Museum and Metro Louisville Communicable Disease department that those who public health officials consider at higher risk from possible exposure are being notified. Louisvilles health director put out a statement in The Courier Journal that most of the people at the Speed Ball were at very minimal risk. I was not considered to be at risk since I never interacted with the two individuals even from a distance and was not recommended for testing by health officials.

I believe we need more testing immediately, even among those without symptoms. The nature of COVID-19 put me and us all in a Catch-22 situation. I didnt fit the criteria for testing or quarantine. I had no symptoms and no specific encounter with a COVID-19 positive person. I had, however, traveled extensively in the U.S. and was required to continue doing so to vote in the Senate. That, together with the fact that I have a compromised lung, led me to seek testing. Despite my positive test result, I remain asymptomatic for COVID-19.

For those who want to criticize me for lack of quarantine, realize that if the rules on testing had been followed to a tee, I would never have been tested and would still be walking around the halls of the Capitol. The current guidelines would not have called for me to get tested nor quarantined. It was my extra precaution, out of concern for my damaged lung, that led me to get tested.

Perhaps it is too much to ask that we simply have compassion for our fellow Americans who are sick or fearful of becoming so. Thousands of people want testing. Many, like Daniel Newman of The Walking Dead, are sick with flu symptoms and are being denied testing. This makes no sense.

The broader the testing and the less finger-pointing we have, the better. America is strong. We are a resilient people, but were stronger when we stand together.

Here is what one person tweeted in response to his statement:

You did not need to go to the gym. Americans all over this country cannot go to theirs, or do much of anything else. You felt you could do as you pleased and risked others. I hope you recover well, but you are not excused from being entirely selfish and overly privileged.

And, our favorite: Atlas Coughed.

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The Social-Distancing Culture War Has Begun – The Atlantic

Posted: at 6:01 am

When I asked whether the virus had interfered with his lifestyle, Bret laughed. Oh, Im going to the shooting range tomorrow, he replied.

Was he worried that his friends might disapprove if they found out?

No, he told me, around here, I get much more of people saying, Why dont you go Saturday so I can go, too?

Terry Trahan, a manager at a cutlery store in Lubbock, Texas, acknowledged that a certain toxic tribalism was informing peoples attitudes toward the pandemic. If someones a Democrat, theyre gonna say its worse, he told me, and if someones a Republican, theyre gonna say its bad, but its getting better.

As an immunocompromised cancer survivor, Trahan said hes familiar with commonsense social-distancing practices. But as a conservative, hes become convinced that many Democrats are so invested in the idea that the virus will be disastrous that theyre pushing for prolonged, unnecessary shutdowns in pursuit of vindication.

Among experts, there is a firm consensus that social distancing is essential to containing the spread of the virusand they warn that politicizing the practice could have dangerous ramifications. This is a pandemic, and shouldnt be played out as a skirmish on a neighborhood playground, Dina Borzekowski, a professor at the University of Maryland School of Public Health, recently told Stat. (For the moment, at least, the scientists seem to have brought the president around: Yesterday, Trump announced he was extending social-distancing guidance until the end of April.)

Read: The four possible timelines for life returning to normal

Of course, not everyone who flouts social distancing is making a political statement. Many have to work because they cant afford not to; others are acting out of ignorance or wishful thinking. Beyond personal behavior, there is a legitimate debate to be had about how to balance economic demands while combatting a global pandemic.

Still, the polarization around public health seems to be accelerating: In recent days, Republican governors in Alabama and Mississippi have resisted calls to enact more forceful mitigation policies. Polling data suggest that Republicans throughout the U.S. are much less concerned about the coronavirus than Democrats are. According to a recent analysis by The New York Times, Trump won 23 of the 25 states where people have reduced personal travel the least.

Some of this is likely shaped by the fact that the most serious outbreaks so far in the U.S. have been concentrated in urban centers on the coasts (a pattern that may not hold for long). But there are real ideological forces at work as well.

Katherine Vincent-Crowson, a 35-year-old self-defense instructor from Slidell, Louisiana, has watched in horror this month as businesses around her city were forced to close by state decree. A devotee of Ayn Rand, Vincent-Crowson told me Louisianas shelter-in-place order was a frightening example of government overreach.

It feels very militaristic, she said. Im just like, What the hell, is this 1940s Germany?

But when we spoke, she seemed even more aggravated by the self-righteous people on social media who spend their time publicly shaming anyone who isnt staying locked in their house. It really reminds me of my kids who tattle on their siblings when they do something bad, she said. Im a libertarian I dont really like being told what to do.

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How Coronavirus is shaking up the moral universe – Economic Times

Posted: at 6:01 am

By John Authers

The coronavirus pandemic is a test. Its a test of medical capacity and political will. Its a test of endurance and forbearance, for believers a test of religious faith. Its a test, too, of a different kind of faith, in the strength of the ideas humans choose to help them form moral judgments and guide personal and social behavior.

The epidemic forces everyone to confront deep questions of human existence, questions so profound that they have previously been answered, in many different ways, by the greatest philosophers. Its a test of where all humans stand.

What is right and what is wrong? What can individuals expect from society, and what can society expect of them? Should others make sacrifices for me, and vice versa? Is it just to set economic limits to fighting a deadly disease?

The lieutenant governor of Texas thinks that those over 70 shouldnt sacrifice the country by shutting down economic activity, but should instead be ready to sacrifice themselves. A 22-year-old partying on Spring break in Florida becomes a social media sensation with a different critique of social distancing, saying, If I get corona, I get corona. Consciously or not, both men are placing themselves in distinct moral traditions.

Several philosophies of social justice have claimed wide adherence in the modern world. They do not line up neatly with party political labels, and most people have sympathy for more than one. Here is a guide to some of the leading idea systems undergirding competing conceptions of right and wrong. Each is being put to the test. As you are put to the test, which do you choose?

RawlsiansMany westerners are Rawlsians without knowing it. Fifty years ago, the Harvard philosopher John Rawls tried to work out how people would construct their society if the choice had to be made behind what he called a veil of ignorance about whether they will be rich, poor or somewhere in-between. Faced with the risk of being the worst off, Rawls posited, humans would not demand total equality, but would need to be assured of the trappings of a modern welfare state. The assurance of basic necessities and the opportunity to do better would form the foundation for social and political justice and provide the ability for people to assert themselves.

Rawlss monumental 1971 book, A Theory of Justice, is now regarded as the clearest moral and intellectual justification for modern center-left mixed economies. But the idea comes from somewhere deeper. Rawls was not religious, but his philosophy is essentially in line with the golden rule handed down by the Old Testament prophets and by Jesus, that we should do as we would want to be done by. Some religious leaders have approached the awful dilemmas presented by the coronavirus just as Rawls would, by taking treatment of the worst off as the criterion for social action.

I hope the lessons we take from our countrys experience with Covid-19 arent about food or avoiding the spread of germs, wrote Russell Moore, the president of the Ethics and Religious Liberty Commission of the Southern Baptist Convention in the New York Times, but about how we treat the most vulnerable among us. A pandemic is no time to turn our eyes away from the sanctity of human life.

Pope Francis also invoked sympathy for the most afflicted as he addressed a prayer to an empty St. Peters Square. "We have realized that we are on the same boat, all of us fragile and disoriented, but at the same time important and needed, all of us called to row together, each of us in need of comforting the other," he said.

Perhaps because of their religious resonance, Rawlsian ideas have guided the approach to the pandemic chosen by authorities in the western world. Societies are mobilizing, and governments are taking extra powers to mandate claustrophobic lockdowns in a bid to minimize the death and suffering of the weakest.

Even those who arent religious tend to accept the logic of the veil of ignorance. If a person is unwilling to be abandoned, governments are not entitled to give up on them; they must do their best to protect everyone, particularly the weakest.

UtilitariansOther philosophies produce very different ways of dealing with the epidemic. Under utilitarianism, most associated with the 19th-century British philosopher John Stuart Mill, rulers must be guided to the total happiness, or utility, of all the people, and should aim to secure the greatest good for the greatest number.

In Victorian Britain, this was a radical creed, and the first utilitarians were passionate liberal reformers. But the utilitarian calculus opens up a new possibility that in situations such as a pandemic, some people might justly be sacrificed for the greater good. It would benefit society to accept casualties, the argument goes, to minimize disruption.

Explicit utilitarian thinking still seems beyond the pale. Last weekend, Britains Sunday Times reported that Dominic Cummings, chief adviser to Prime Minister Boris Johnson, had advocated in private meetings a policy of letting enough people get sick to establish nationwide herd immunity, protect the economy, and if that means some pensioners die, too bad. It caused an outcry and met with an immediate and impassioned denial by Downing Street. Even Cummings, an iconoclast, refused to be attached to such brutally utilitarian ideas.

Mill himself would not have advocated putting money ahead of peoples lives, but a utilitarian calculus is not about balancing money and life. If a recession could lead to shorter lives and widespread misery, it is possible that making less of an attempt to save every last life from the pandemic now could lead to greater total happiness.

In the U.K., a paper by an academic at the University of Bristol used mathematical techniques developed to measure the cost-efficiency of safety measures in the nuclear power industry to calculate the likely savings of human life by different approaches to the virus, and found that a 12-month lockdown followed by vaccinations would be best. But it cautioned that this would only create a net saving of life if the reduction in gross domestic product could be kept to 6.4% or less.

That paper, broadcast on the BBC, provoked a fiery response from economists, and some research suggests counterintuitively that recessions lengthen lives. Most people find the mere attempt at such an exercise callous, but its difficult to dismiss it. Governments and insurers do indeed put a notional price on a human life when setting policy. Must every last patient be given the utmost care if this plan of action causes greater suffering in the long run? Or, as President Donald Trump put it: We cant have the cure be worse than the problem.

Its intuitive to view moral problems through a utilitarian lens and then to find outcomes like this distasteful, and to reject them because they conflict with the golden rule. If the lockdowns drag on for months, utilitarian ideas may bubble back to the surface.

LibertariansThe libertarian place in American thought is long and distinguished. Its lineage goes back at least to the Enlightenment philosopher John Locke and the founding fathers, and in its modern incarnation gains inspiration from the author Ayn Rand, who outlined her ideas in novels and essays. For her, man had a right to live for himself and an individuals happiness cannot be prescribed by another man or any number of other men.

The most famous libertarian thought experiment was conducted by another Harvard philosopher, Robert Nozick, in a riposte to Rawls. He imagined what kind of political state would be built, and how much personal liberty citizens would surrender, if everyone were dropped into a utopian landscape with no social structures. The novelist William Golding gave one answer in The Lord of the Flies. To avoid the descent into violence that the schoolboys of Goldings novel endure, Nozick, in Anarchy, State and Utopia, reckoned that people would set up a very limited state dedicated to self-defense and the protection of individual rights but nothing more.

The western coronavirus response has hugely expanded state powers and limited individual rights with little debate, and to date populations have consented to privations that Rand and Nozick argued they should never accept.

But wait. There have been objections to lockdowns on the libertarian basis that they infringe on rights. Critiques are appearing saying that politicians havent proven that such drastic measures are necessary. Before the coronavirus, the U.S. suffered a measles epidemic as the result of anti-vaccination activism, a libertarian cause that put parents right to choose not to vaccinate their children above the states attempt to defend other parents right to expect that their own children wouldnt have to mix with unvaccinated peers. Panic buying, and hoarding of medical equipment also show that many people are following Rands idea of self-determination and putting themselves first. Such ideas may grow more appealing after a few more weeks of self-isolation.

In public spaces around the world, libertarians are in conflict with the state. Social media is full of images of big social gatherings, often in luxurious social settings. If I get corona, I get corona, as the 22-year-old said on video in Florida. At the end of the day, Im not gonna let it stop me from partying. Oklahomas governor even felt the need to tweet that he was at a packed restaurant.

Libertarians are not only found on the political right. As the crisis began to unfold, the American Civil Liberties Union made a statement accepting that civil liberties must sometimes give way when it comes to fighting a communicable disease but only in ways that are scientifically justified. It said, The evidence is clear that travel bans and quarantines are not the solution.

The right to walk in a park looks like a flash point. New York Governor Andrew Cuomo was furious to see crowds expressing libertarian sympathies whether they saw it that way or not by gathering in parks. Its arrogant, Cuomo said. Its self-destructive. Its disrespectful to other people. And it has to stop and it has to stop now!

New Yorkers are organizing to keep the parks open.

In these conditions, individual choices become freighted with moral significance. How, for example, will society eventually judge behavior like that of Kentucky Senator Rand Paul? Arguably the most prominent libertarian in the U.S., he continued to socialize as normal for a week after being told that he had had contact with someone who tested positive for the coronavirus. He had no symptoms. Recall that there are many elderly members of the Senate. Last weekend, after a workout in the Senate gym, he discovered that he had himself tested positive.

CommunitariansYet another approach is based on the notion that everyone derives their identify from the broader community. Individual rights count, but not more than community norms. These notions go back to the Greeks, but in modern times, the philosophy is most widely connected to the sociologist Amitai Etzioni and philosopher Michael Sandel. Sandels Liberalism and the Limits of Justice is another riposte to Rawls, arguing that justice cannot be determined in a vacuum or behind a veil of ignorance, but must be rooted in society. He sets out a theory of justice based on the common good.

Speaking last week to Thomas Friedman of the New York Times, Sandel said: The common good is about how we live together in community. Its about the ethical ideals we strive for together, the benefits and burdens we share, the sacrifices we make for one another. Its about the lessons we learn from one another about how to live a good and decent life.

The virus has attacked in exactly this place, depriving everyone of life in a community. And communitarian ideas are showing themselves. Across Europe, people on lockdown have arranged to go to their windows and balconies to applaud their national health services. These are seen as bedrocks of society. At Londons Olympic opening ceremony in 2012, a pageant of Britishness, the organizers celebrated the National Health Service with dancing nurses wheeling hospital beds. For many countries with a modern welfare state, celebrating and supporting the workers of their public-health service is seen as a communitarian duty.

This is a critical point of difference with the U.S., where the expansion of medical care is a hugely contentious issue. Communitarians like Princetons Michael Walzer argue that any system of medical provision requires the constraint of the guild of physicians. The coronavirus promises to bring this debate to a head.

Communitarianism also underlies much social conservative thought. When the very conservative Republican Texas Lieutenant Governor Dan Patrick said on Fox News that the rest of the country should not sacrifice itself for the elderly, he was making a communitarian argument, not a utilitarian one.

No one reached out to me and said, As a senior citizen, are you willing to take a chance on your survival in exchange for keeping the America that all America loves for your children and grandchildren? Patrick, who is 63, told the host Tucker Carlson. And if thats the exchange, Im all in.

In this telling, it is the patriotic duty of the elderly not to force privations on their country, and make life worse for their grandchildren. Such a communitarian ethic has always resonated within the U.S. (just read Alexis de Tocqueville), and it provoked an outcry on social media.

China practiced another kind of communitarianism after the coronavirus first appeared in Wuhan in January. The people of that city were told to lock themselves in, and often forcibly quarantined, for the good of the community and the state, largely identified with the Communist Party. Under Xi Jinping, the Party has rehabilitated the Confucian thought that long justified obedience to a hierarchical and authoritarian but benevolent state. That the notion of social solidarity remains strong showed in the spectacular discipline with which China and other Asian nations dealt with the problem.

We Are All Rawlsians NowFor now, the approach being adopted across the West is Rawlsian. Politicians are working on the assumption that they have a duty to protect everyone as they themselves would wish to be protected, while people are also applying the golden rule as they decide that they should self-isolate for the sake of others. We are all Rawlsians now.

How long will we stay that way? All the other theories of justice have an appeal, and may test the resolve to follow the golden rule. But I suspect that Rawls and the golden rule will win out. That is partly because religion even if it is in decline in the West has hard-wired it into our consciousness. And as the epidemic grows worse and brings the disease within fewer degrees of separation for everyone, we may well find that the notion of loving thy neighbor as thyself becomes far more potent.

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Society’s ‘invisible bonds’ come into the light – Newsroom

Posted: at 6:01 am

MARCH 30, 2020 Updated March 30, 2020

Dr Neal Curtis is Associate Professor of Media and Communication at the University of Auckland.

Ideasroom

Dr Neal Curtis looks at all the points of implicit trust within society, and how Covid-19 is revealing how important this trust is

As I stood in the queue to get into our local supermarket it was encouraging to see how carefully people were engaging in social distancing to minimise the spread of coronavirus. Admittedly, it was a beautiful sunny morning and we are still only a few days into the lockdown, but everyone seemed to be stoically accepting the inconvenience, with many in decidedly good spirits.

Speaking to the woman stood two metres behind me, it dawned on me just how much more aware of her I was than if this were a normal visit under usual conditions. My awareness of her did not stem from any sense of threat or danger, but from the recognition that as I was thinking about her,she was thinking about me. Curiously, our practice of distancing had actually brought us closer, not physically, of course, but in terms of being mindful.

Ordinarily I would get through the shopping as quickly as possible. I would no doubt need to exercise some form of etiquette to let another shopper pass in a crowded aisle, but awareness of being connected to that person would be minimal, if non-existent. That seems quite different now.

In a 1987 interview for Womans Own, Margaret Thatcher famously declared "theres no such thing as society. There are individual men and women and their families". In saying this, she was drawing together words from two of her favourite thinkers, Ayn Rand and Milton Friedman. Her claim was, of course, just another way for her to justifyrolling back the state, depleting public services and embarking on widespread asset sales and privatisation, but she was also making a more significant moral claim about an absence of both dependency on and responsibility for others.

I am struck that if there were only self-reproducing and self-sufficient individuals and their families, the current situation would be much less of a problem. Wouldnt we all just be carrying on, untouched by what is going on around us? The crisis, aside from the very grave dangers of the virus and the risk to life, is in fact heightened precisely because we are all interconnected and dependent on each other. This is not just to do with the corporate sector continuing to function, but a whole set of social institutions relating to health, education, transport, and communication (official and interpersonal) that support the complex functioning of our daily lives.

We have also become increasingly aware of jobs that are done in the background, the importance of which we regularly fail to register. It is different now. Consequently, Ive been thinking about a little book by Geoffrey Hosking called Trust: Money, Markets and Society. This is a book whose brevity and diminutive size belies the importance of its argument. What I believe the current crisis has brought into relief or revealed like lemon juice on invisible ink is what Hosking calls "unreflective trust". By this he means the amount that we do in fact dependon others without consciously acknowledging it.

Talking about travelling by air, he writes: "Which of us before boarding an aircraft, demands to see the pilots qualification to fly it, or checks every rivet, joint and fuel duct in it? Or even the competence of the engineers responsible for maintaining and repairing those parts. Obviously we do not. Yet our lives depend on the impeccable working order of every one of those parts, and on the skill and conscientiousness of the engineers. The fact is we take them on trust because everyone else does so and because aeroplanes very seldom crash. Besides, to do otherwise would require us to have time and skills we dont possess. We dont 'decide'to board an aircraftwe just do it."

In this process, we rely on and trust the workings of society in all its complex, manifold, and interlacing facets. We trust symbolic systems such as the sciences of aeronautics, mechanics, and metallurgy; we trust institutions of regulation and oversight, of teaching and training; we trust corporate health and safety standards; and we trust the media to accurately report risk. Now imagine for a moment just driving through a busy city in the morning and all the points at which your unreflective trust is implicit but absolutely necessary.

"Trust", Hosking argues, "especially unreflective trust is part of the deep grammar of any society. It generates the templates within which people relate to each other, and within which they think and feel about how to face the future". These are societys "invisible bonds", and while there remains a constituency that wants to belittle and decry the actions of the government, I really hope that something good can come from so many of us beginning to see these bonds.

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The Vicious Cycle Between Psoriasis and Mental Health – Self

Posted: at 6:00 am

The skin is the bodys largest organismit is its defense against the worldso it makes sense that the immune system is very active in the skin, Tina Bhutani, M.D., M.A.S., a dermatologist and codirector of the University of California San Francisco (UCSF) Psoriasis and Skin Treatment Center and of the UCSF Dermatology Clinical Research Unit, tells SELF. But, she adds, researchers arent sure why some people get psoriasis and others dont.

We know patients have a genetic predisposition, but in addition, theres something environmental that happens to trigger their psoriasis, Dr. Bhutani explains. In some, that might be an infection, in others that might be some kind of stressor, like a psychological or physical stress on the body.

Research has shown that psoriasis can contribute to or worsen various mental health conditions, including depression, anxiety, bipolar disorder, eating disorders, and more. If you have psoriasis, you might be intimately familiar with how this worksespecially right now, given that basically all of us are feeling mental strain in unprecedented ways thanks to the new coronavirus.

While its a bit of a chicken-and-egg situation, Dr. Bhutani says that mental health conditions like anxiety or depression may kickstart the onset of psoriasis or trigger and exacerbate flare-ups. Beyond that, There are studies showing that major stressful life events, such as a death in the family, can result in the new onset of psoriasis, Joel Gelfand, M.D., MSCE (Master of Science in Clinical Epidemiology), professor of dermatology and epidemiology and director of the Psoriasis and Phototherapy Treatment Center at the Perelman School of Medicine at the University of Pennsylvania, tells SELF.

On the other hand is the fact that having psoriasis may contribute to you developing a mental health condition (or make it worse). There are studies that show patients with psoriasis are more likely to develop issues such as anxiety and depression over time, Dr. Gelfand says.

Anyone who has worried about not fitting in with narrow definitions of beauty can understand how having a visible skin condition could take a toll on someones mental health. One can imagine how the physical [stigma] of psoriasisespecially when plaques affect exposed areas of the skincan affect mood and interpersonal interactions in a negative way, Evan Rieder, M.D., an assistant professor of dermatology at NYU Langone who is board-certified in both psychiatry and dermatology, tells SELF. These can happen both through how someone with psoriasis views [themselves], but also through the reactions of others to their skin.

Like many people with psoriasis, Jennifer Pellegrin, 36, knows all too well how the condition can impact a persons social life and mental health. She was diagnosed with psoriasis when she was 15 and with psoriatic arthritis at 25, followed by depression a year later and then anxiety. Psoriasis causes an exacerbation of my [mental health conditions], she tells SELF in an email. I go through days sometimes where I cancel all plans. I can be looking forward to going out, start to get ready, and boom: Anxiety hits. I feel hideous and wont leave the house.

In addition to the more obvious ways psoriasis and mental health can play off each other, experts have done a fair amount of research into the biological mechanisms that may connect psoriasis and various mental health conditions. A 2016 systematic review in the Journal of Clinical and Aesthetic Dermatology looked at 57 studies on the subject, noting that psychological stress and depression can boost the release of pro-inflammatory cytokines, which are molecules released as part of the immune response. The inflammation they cause seems capable of further exacerbating the symptoms of both psoriasis and conditions like depression. However, theres conflicting research on this; some of the literature hasnt found definitive associations between psoriasis and psychological issues like stress.

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3SBio Unveils 2019 Annual Results: Revenue Rises by 16.0%, Normalized Net Profit attributable to owners of the parent Jumps by19.4%, R&D Expenses Soar…

Posted: at 5:59 am

HONGKONG, March 31, 2020 /PRNewswire/ -- Chinese leading biopharmaceutical company 3SBio (01530.HK) today released its 2019 annual results, showing that the Company maintained steady growth, with core products continuously leading the market and more products being included into drug reimbursement lists. The Company has also been on track to advancing R&D pipelines, and stepping up efforts to introduce innovative therapies for cancer and autoimmune diseases into global markets. In the future, 3SBio will further boost its advantages with a comprehensive platform that integrates R&D, manufacturing, commercializationand investment cooperation, while consolidating and improving its status as a leading biopharmaceutical company.

Realizing sound business performance; sales of TPIAO exceeding RMB 2 billion

In 2019, 3SBio's revenue rose by 16.0% year on year to approximately RMB 5.318 billion. Gross profit increased by 18.5% to approximately RMB 4.393 billion. Normalized net profit attributable to owners of the parent added by 19.4% to approximately RMB13.92 billion.

The Company's four core products, including TPIAO, Yisaipu, EPIAO and SEPO, remained market leaders in China. Sales of TPIAO, which is the world's only commercialized recombinant human thrombopoietin ("rhTPO"), for the treatment of thrombocytopenia, soared 39.1% to exceed RMB 2 billion, with its market share jumping to 73.2%. Yisaipu, a product to treat rheumatoid arthritis , ankylosing spondylitis and psoriasis, had a market share of 60.9%. Two recombinant human erythropoietin ("rhEPO") products, EPIAO and SEPO, maintained market-leading positions, with their market share improving to 41.6%. As there is huge unmet demand for biologics in China, TPIAO and Yisaipu, which have low penetration rates, will see significant growth potential in the future.

Several of the Company's products and indications have been added into the updated 2019 National Reimbursement Drug List (NRDL), including Shinuo, a fluticasone propionate cream for the treatment of multiple skin diseases, the new indication of Yisaipu for the treatment of adult patients with severe plaque psoriasis, and the new indication for EPIAO for the treatment of anemia caused by chemotherapy for non-myeloid malignant tumors. Humulin, a mixed protamine zinc recombinant human insulin injection, was upgraded to Class A from Class B in the NRDL. Byetta, a therapy for the treatment of patients with type 2 diabetes, was added into the NRDL through negotiations.

Also, Xenopax, the first approved recombinant humanized anti-CD25 monoclonal antibody injection in China, was granted the Chinese GMP certificate and launched in the market in October, 2019.

R&D expenses up 45.2%, with follow-up pipelines on 'fast track'

In 2019, 3SBio's R&D expenses soared by 45.2% to approximately RMB 527 million. The Company has its best-ever pipeline of biological cancer therapies, including anti-HER2, CD20, PD1, EGFR and VEGF antibodies. The Company's pipeline of biological therapies for the treatment of autoimmune and inflammatory diseases, including anti-TNFa, IL-17A and IL-5 antibodies, has all made significant progress.

302H (Inetetamab), an anti-HER2 monoclonal antibody drug, has completed the technical review, clinical trial site inspection as well as manufacturing site inspection. An application for manufacturing approval of pre-filled aqueous injection solution of Yisaipu has been filed and accepted by the National Medical Products Administration, and it is currently under the review process.

In 2019, the Company's drug candidates received five IND approvals, including: anti-PD1 antibody for the treatment of various cancers (simultaneous applications in China and the US); anti-IL-17A antibody for the treatment of moderate to severe plaque psoriasis; TRK820 (Remitch) for the treatment of pruritus in hemodialysis patients; and HIF-117 capsules for the treatment of anemia. In February 2020, the Company's anti-IL-5 antibody for the treatment of asthma was approved for a clinical trial.

The Company has also been proactively expanding new indications and second-generation products of existing products, including NuPIAO, a second-generation rhEPO; RD001, a pegylated long-acting rhEPO; and the pediatric ITP indication of TPIAO.

Story continues

Also, the Company selected Verseau Therapeutics Inc's VTX-0811, a monoclonal antibody targeting PSGL-1 for the treatment of multiple types of cancer, as the first licensed program under the partnership in the field of immuno-oncology.

3SBio's R&D highlights in 2019

3SBios R&D highlights in 2019

As of December 31, 2019, amongst the 32 product candidates within the Company's active pipeline, 22 were being developed as National New Drugs in China (including registration Class I and Biologics Class II), including 11 in oncology, 12 in autoimmune and other diseases, 6 in nephrology, 2 in metabolic diseases and 1 in dermatology.

Expanding global presence in therapies for cancer and autoimmune diseases

In 2019, 3SBio was continuously expanding external partnerships and global presence for its innovative therapies in the fields of cancer and autoimmune diseases, including the partnership with global biologics giant Samsung Bioepis in South Korea for the development of biosimilar candidates; collaboration with Verseau Therapeutics in the United States for global clinical development of macrophage checkpoint modulators; partnership with Taiwan Liposome Company for the development of innovative liposomal products; and collaboration with Numab to develop new multispecific antibodies for cancer immunotherapy. The Company also invested GenSight and Sensorion to explore innovative gene therapies for ophthalmic diseases and innovative treatments for inner ear diseases.

In early 2020, the Company became a limited partner in the MPM Oncology Innovations Fund (INV), and agreed to make donation to support early-stage oncology research at Dana-Farber Cancer Institute, a world-leading cancer research and treatment center.

These collaborations demonstrated 3SBio's excellent expertise in international development and operation, while laying a key stepping stone for its future globalization strategy. The Company will continue to pursue selective mergers and acquisitions and collaboration opportunities and explore cutting-edge innovative therapies in early stages, with an aim to enrich its existing product portfolio and become a leader in next-generation immuno-oncology therapies.

Comprehensive platform with strong competitive advantages

In the future, 3SBio intends to reinforce its position as a leading biopharmaceutical company in China by continuously leveraging its integrated R&D, manufacturing, commercializationand investment cooperation platforms. The Company will also focus on developing innovative biologics products to address unmet medical needs to benefit more patients.

The Company will fully integrate the R&D teams of nearly 400 people on multiple R&D platforms, and actively develop innovative therapies including monoclonal antibodies, bispecific antibodies, antibody fusion proteins, and cell therapies, thereby bringing a variety of treatment options to patients. The Company will kick off multiple phase III clinical trials this year, file new drug applications for more than 10 products in the next 3 years, and also submit IND applications for10-15 new monoclonal antibodies and bispecific antibodies (simultaneous applications in China and the US).

The Company has approximately 38,000-liter capacity in mAb facility, mammalian cell-based, bacteria cell-based and small molecule manufacturing facilities, and more than 27 years of experience in manufacturing biologics medicines. With large-scale production capacity that meets international quality standards, the Company is able to continuously supply the market with high-quality biologics. Over nearly 3 decades, the Company has been well recognized for its strong commercial operation capabilities and sales network throughout the country, which supports its sustainable growth.

Dr. Jing LOU, Chairman and CEO of 3SBio, commented: "Under the backdrop of the COVID-19 pandemic globally, 3SBio supports the country in our own way, through thick and thin. As we face a market environment where opportunities and challenges coexist, 3SBio is still maintaining strong growth momentum by leveraging our well-established systems that we've developed over the years. we will strive to overcome all difficulties, accelerate clinical applications and progress for our pipeline. We will also expand our production capacity and give full play to the advantages of our integrated platform. We aim to become a globally leading Chinese biopharmaceutical company, and continuously improve the availability of innovative biologics to benefit more patients."

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3SBio Unveils 2019 Annual Results: Revenue Rises by 16.0%, Normalized Net Profit attributable to owners of the parent Jumps by19.4%, R&D Expenses Soar...

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Global Psoriasis Treatment Market Industry Analysis and forecast (2019 to 2026) – Stock Market Herald

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Global Psoriasis Treatment Market was valued US$ XX Bn in 2018 and is expected to reach US$ XX Bn by 2026, at CAGR of 9.3 % during forecast period of 2019 to 2026.

Psoriasis is a long-lasting autoimmune disease characterized by patches of abnormal skin growth, skin patches are typically red, dry, itchy, and scaly.

Global Psoriasis Treatment Market Drivers and Restrain

Rising prevalence of the condition, heading with growing awareness, the screening and diagnosis of the disease are expected to fuel the global psoriasis treatment market in the coming years. Psoriasis treatment options also contribute to a number of side-effects such as liver and kidney damage, hypertension, and increased risk of cancer, etc., are the factors could hamper the growth of Global Psoriasis Treatment Market in forecast period.

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Global Psoriasis Treatment Market key segmentation

By drug class, the global market has been categorized into TNF inhibitors, Interleukin inhibitors, Vitamin D analogs, Corticosteroids, and others. Tumour Necrosis Factor Inhibitors is further categorized as Adalimumab, Infliximab, Etanercept. Vitamin D Analogues is segmented into Calcitriol, Calcipotriol, Tacalcitol. The Interleukin inhibitors segment is projected to lead the global psoriasis treatment market during the forecast period.

High market share of the interleukin inhibitors segment can be attributed to the superior efficacy and safety of drugs in this class for the treatment of psoriasis. Moreover, the acceptance of this drug class is attributable to interleukin blockers, which are considered to be a viable option for patients having trouble responding to other treatment.

Global Psoriasis Treatment Market Regional Analysis

By region, the global psoriasis market to witness dominance of North America followed by Europe. As per the National Psoriasis Foundation, there are about X million people in America living with psoriasis. Because of quick adoption of biological therapy and rise in investments on research and development for clinical trials will drive global market in this region. On the other side, the emerging markets in the Middle East and Africa, Latin America, and Asia Pacific are expected to offer growth opportunities thanks to increasing patient pool, the improving healthcare infrastructure and medical facilities.

The objective of the report is to present comprehensive analysis of Global Psoriasis Treatment Market including all the stakeholders of the industry. The past and current status of the industry with forecasted market size and trends are presented in the report with the analysis of complicated data in simple language.

The report covers all the aspects of industry with dedicated study of key players that includes market leaders, followers and new entrants by region. PORTER, SVOR, PESTEL analysis with the potential impact of micro-economic factors by region on the market have been presented in the report. External as well as internal factors that are supposed to affect the business positively or negatively have been analyzed, which will give clear futuristic view of the industry to the decision makers.

The report also helps in understanding Global Psoriasis Treatment Market dynamics, structure by analyzing the market segments, and project the Global Psoriasis Treatment Market size. Clear representation of competitive analysis of key players by Psoriasis Treatment Type, price, financial position, product portfolio, growth strategies, and regional presence in the Global Psoriasis Treatment Market.

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Scope of the Global Psoriasis Treatment Market

Global Psoriasis Treatment Market Drug class

Corticosteroids Tumour Necrosis Factor Inhibitors interleukin inhibitors Vitamin D AnaloguesGlobal Psoriasis Treatment Market by Treatment

Biologic Drugs Small Molecule Systemic Drugs Tropical TherapiesGlobal Psoriasis Treatment Market by Route of administration

Oral Parenteral TopicalGlobal Psoriasis Treatment Market by region

North America Europe Asia Pacific Middle East & Africa South AmericaKey players operating on Global Psoriasis Treatment Market

AbbVie Inc., Amgen Inc., AstraZeneca, Biogen, Boehringer Ingelheim, Celgene, Eli Lilly and Company, Johnson & Johnson, LEO Pharma A/S, Merck & Co., Inc., Novartis AG, Pfizer, Inc., Stiefel Laboratories Inc. (GlaxoSmithKline plc.), Sun Pharmaceutical Industries

MAJOR TOC OF THE REPORT

Chapter One: Psoriasis Treatment Market Overview

Chapter Two: Manufacturers Profiles

Chapter Three: Global Psoriasis Treatment Market Competition, by Players

Chapter Four: Global Psoriasis Treatment Market Size by Regions

Chapter Five: North America Psoriasis Treatment Revenue by Countries

Chapter Six: Europe Psoriasis Treatment Revenue by Countries

Chapter Seven: Asia-Pacific Psoriasis Treatment Revenue by Countries

Chapter Eight: South America Psoriasis Treatment Revenue by Countries

Chapter Nine: Middle East and Africa Revenue Psoriasis Treatment by Countries

Chapter Ten: Global Psoriasis Treatment Market Segment by Type

Chapter Eleven: Global Psoriasis Treatment Market Segment by Application

Chapter Twelve: Global Psoriasis Treatment Market Size Forecast (2019-2026)

Browse Full Report with Facts and Figures of Psoriasis Treatment Market Report at: https://www.maximizemarketresearch.com/market-report/global-psoriasis-treatment-market/37175/

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Global Psoriasis Treatment Market Industry Analysis and forecast (2019 to 2026) - Stock Market Herald

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(Bloomberg) -- The U.S. became the first country to reach 100,000 coronavirus cases. Italy had its deadliest day with almost 1,000 fatalities. British Prime Minister Boris Johnson and his health secretary tested positive.President Donald Trump ordered General Motors to start making ventilators by invoking a Cold War-era law. Toyotas idled U.S. manufacturing facilities will make much-needed face shields and masks.New York Mayor Bill de Blasio said new infections will be astronomical. Los Angeles Mayor Eric Garcetti warned his city may see a New York-like surge in less than a week.Key Developments:Cases top 585,000; 26,800 dead, 130,000 recovered: Johns HopkinsU.S. cases top 100,000, more than Italy, ChinaU.S. ramps up virus testing, but demand still outpaces supplyWorkers critical to worlds food supply falling illU.K. orders unprecedented shutdown of housing marketTokyo braces for critical weekendFrom Spain to Germany, farmers warn of fresh food shortagesSubscribe to a daily update on the virus from Bloombergs Prognosis team here.Click VRUS on the terminal for news and data on the coronavirus and here for maps and charts. For analysis of the impact from Bloomberg Economics, click here. To see the impact on oil and commodities demand, click here.U.S. Becomes First Nation With 100,000 Cases (5:27 p.m. NY)The U.S. became the first country to surpass 100,000 confirmed cases of the coronavirus on Friday, a day after it overtook China to become the largest outbreak in the world. Americas most prominent hot spots are New York and New Jersey, which together account for half the countrys total cases. California has more than 4,000.L.A. Warns of New York-Level Surge in Five Days (5:06 p.m. NY)Los Angeles could see a coronavirus surge similar to New York Citys in five days if the spread continues at the rate its been going, Mayor Eric Garcetti said.We will have doctors making excruciating decisions, Garcetti said at a press briefing alongside Governor Gavin Newsom. They spoke in front of the U.S. Navy hospital ship Mercy, which docked in Los Angeles to lend extra medical space for non-coronavirus needs. It will be the largest hospital in the city, Garcetti said.Rhode Island Stops Cars With N.Y. Plates (5 p.m. NY)Rhode Island police, aided by the National Guard, on Saturday will conduct house-to-house searches to find people who traveled from New York to demand they begin 14 days of self-quarantine. State police are already stopping cars with New York license plates.Right now we have a pin-pointed risk, Governor Gina Raimondo said. And that risk is called New York City.Raimondo, a Democrat, said she consulted lawyers and while she couldnt close the border, she felt confident she could enforce a quarantine. Many New Yorkers have summer houses in the state, especially in tony Newport, and the governor said authorities would be checking there.Trump Signs $2 Trillion Stimulus Bill (4:47 p.m. NY)President Donald Trump signed the largest stimulus package in U.S. history, a $2 trillion aid bill intended to rescue the economy. The plan will provide a massive injection of loans, tax breaks and direct payments to large corporations, small businesses and individuals whose revenue and income have plummeted under social distancing restrictions.Read full story hereFour Die on Holland America Cruise Ship (4:30 p.m. NY)Carnival Corp.s Holland America line said four passengers died on its Zaandam ship, which has had an outbreak of flu-like symptoms on board, including at least two confirmed cases of Covid-19. The cruise line said the passengers were older but didnt say how they died.The Zaandam, currently near Panama, was still at sea when cruise companies halted new voyages earlier this month.Trump Orders GM to Make Ventilators (4 p.m. NY)President Donald Trump ordered General Motors Co. to immediately begin making ventilators, invoking a Cold War-era defense act amid productive talks with the automaker.Our negotiations with GM regarding its ability to supply ventilators have been productive, but our fight against the virus is too urgent to allow the give-and-take of the contracting process to continue to run its normal course. GM was wasting time, Trump said in a statement. Todays action will help ensure the quick production of ventilators that will save American lives.GM and ventilator maker Ventec Life Systems Inc. had much of what they needed in place to ramp up production of the breathing machines. They were just waiting on the Trump administration to place orders and cut checks.Belgium May Keep Limits Until May 2 (3 p.m. NY)Belgium extended restrictions on citizens and businesses, which took effect March 14, by two weeks until April 19, and Prime Minister Sophie Wilmes signaled a further extension to May 3, saying its too early to declare the epidemic under control. Belgians must stay at home except for essential activities such as grocery shopping. Gatherings by more than two people are banned and stores selling non-essential goods remain closed.N.Y. Seeks Aid for Four New Hospitals (2:45 p.m. NY)New York is seeking federal assistance for four new emergency hospitals, Governor Andrew Cuomo said, as the number of state deaths spiked 35% in a day to more than 500.The new sites would join four centers the U.S. is setting up in the city, he said. The state wants more beds for Nassau, Suffolk and Westchester counties. Cuomo spoke from the Jacob K. Javits Convention Center on Manhattans west side, which is being converted into a 1,000-bed emergency hospital that will open Monday.Cuomo said current demand for medical equipment is adequately covered and that the state is stockpiling additional supplies for a potential peak of infections three weeks from now. We dont need them yet, he said. We need them for the apex.The governor said he would keep the states schools closed for an additional two weeks, at which time the situation will be reassessed.Luxembourg Plans to Test for Herd Immunity (1:30 p.m. NY)Luxembourg is in an intensive planing phase to be among the first nations to research so-called herd immunity based on new blood tests the country is expecting to get, Health Minister Paulette Lenert said Friday.The new tests wouldnt check for Covid-19 infections but whether people have developed immunity against the new virus. Luxembourg, due to its small population of just over 600,000 people, is in a fortunate position to do this, the minister said. Scientists would be able to test samples that would be representative of the entire population, the minister said.Italys Daily Toll Nears 1,000 (12:35 pm. NY)Italy had its highest daily death toll even as the number of new cases declined on Friday. Fatalities shot up to 969, the most in a 24-hour period since the start of the outbreak.New infections totaled 5,959, compared with 6,153 the previous day, civil protection authorities said at their daily news conference in Rome. Italy now has 86,498 total cases, roughly the same number as the U.S. and more than China, where the diseases first outbreak occurred.U.S. Buys More Ventilators (12:30 p.m. NY)President Donald Trump said the federal government bought many ventilators from several companies he didnt identify. Trump in a tweet said the names will be announced later.State and local officials have been pleading with the federal government for more ventilators as cases of the coronavirus mount.France Extends Restrictions (12:20 p.m. NY)French Prime Minister Edouard Philippe said public confinement is being extended to April 15. The restrictions could be further extended if needed, he said in a press conference after a cabinet meeting on Friday. A scientific committee consulted by the government recommends at least six weeks of confinement, he said.Portugals Cases Rise 20% (12:14 p.m. NY)Portugals cases rose 20% to 4,268 from 3,544 a day earlier, the governments Directorate-General of Health said. That compares with a daily increase of 18% reported Thursday and a 27% rise on Wednesday. The total number of deaths increased to 76 on Friday from 60 reported through Thursday morning.Director-General of Health Graa Freitas said the data suggest the peak wont be a moment in time but rather a plateau, and may not occur before May.Libya, Syria Face Catastrophe: WHO (11:35 a.m. NY)Libya reported its first case this week, meaning 21 of 22 Eastern Mediterranean nations have infections. The World Health Organization said Libyas capacity to respond is extremely limited in some areas and non-existent in others, with a large movement of people from neighboring countries.The outbreak also threatens to cause a catastrophe in Syria, the WHO said. Half of the nations hospitals are not functioning after nine years of war and thousands of health workers having fled the country. Millions of displaced people live in overcrowded camps in the countrys northwest, but after two days of tests using 300 WHO kits, no cases so far have been detected, the agency said.Toyota Shifts Factories to Face Shields (11:07 a.m. NY)Toyota Motor Corp.s idled manufacturing facilities in the U.S. will make much-needed face shields and masks, and the Japanese automaker is closing in on deals with medical-device makers to help them boost production.The carmaker said Friday it will start mass production of face shields early next week to supply hospitals near its plants in Indiana, Kentucky, Michigan and Texas. Toyota also said it is finalizing pacts with at least two companies to make breathing ventilators and respirator hoods, and its looking for partners to make protective masks. The company on Thursday extended its shutdown of North American factories for two weeks.U.K. Virus Deaths Jump 30% (10:29 a.m. NY)The number of people in the U.K. who have died from coronavirus increased by 31% to 759 as of Thursday, the Department of Health said. Thats higher than the five-day average of 20%.Some 14,579 have tested positive for the disease as of Friday, an increase of about 25%, above the five-day average of 20%.Two Fed Bankers Confident of Rebound (10:29 a.m. NY)Atlanta Fed President Raphael Bostic and Dallas Fed President Robert Kaplan expressed confidence the U.S. economy will rebound when restrictions on activity are lifted.This is a public health crisis and different from a typical recession, Bostic said on Bloomberg Television Friday. Kaplan offered a similar view a few minutes earlier. We were strong before we went into this, and we believe that weve got a great chance to come out of this very strong, he said.Kaplan said unemployment would peak in the low to mid teens before recovering to around 7%-to-8% by year-end.Coronavirus Response Leaves U.K. Vulnerable: Lancet (9:29 a.m. NY)A delayed response by the U.K. government to the coronavirus pandemic has left the health system wholly unprepared for an expected surge of critically ill patients, according to the editor of the medical journal The Lancet.In a letter posted on the journals website, Richard Horton described chaos and panic across the National Health Service, basing his comments on messages he received from workers. The government last month should have expanded testing capacity, ensured the distribution of protective equipment and stepped up training, he said.U.K. Prime Minister, Health Secretary Have Virus (9:17 a.m. NY)British Prime Minister Boris Johnson will self-isolate in Downing Street for seven days after a test found he had the coronavirus, spokesman James Slack told reporters on Friday. Health Secretary Matt Hancock has also contracted the illness, in a double blow to the U.K. governments response to the crisis.Both men have reported mild symptoms. Meals will be left at Johnsons door while he continues to work by video-conference, Slack said. Hancock is self-isolating and working from home.These are the latest high-profile individuals to contract the virus in Britain after Prince Charles, the heir to the throne, tested positive.U.K. Sees No Change to Brexit Timetable (8:29 a.m. NY)In terms of the timetable theres no change from our point of view, the U.K. prime ministers spokesman James Slack told reporters in a conference call. Slack was asked if there would be an extension to the Brexit transition period beyond December.NYC Mayor Says Trump Needs to Face Reality on Ventilators (8:20 a.m. NY)New York Mayor Bill de Blasio said cases of the new coronavirus are going to become astronomical, putting unprecedented strain on the hospital system. Trump said in an interview on Fox News that he didnt think New York state needed the 30,000 ventilators that Governor Andrew Cuomo has asked for to treat Covid-19 patents with respiratory conditions.When the president says the state of New York doesnt need 30,000 ventilators, with all due respect to him, hes not looking at the facts of this astronomical growth of this crisis, de Blasio said. If they dont have a ventilator, a lot of people are just not going to make it.Rolls-Royce Pauses U.K. Civil-Engine Output (8:07 a.m. NY)Rolls-Royce Holdings Plc will wind down jetliner-engine production in the U.K. as it spends a week implementing cleanup and safety measures to cope with the coronavirus outbreak. The company, which makes turbines for wide-body planes, will significantly reduce all but essential activities within its U.K. civil aerospace facilities from midnight, it said in a statement Friday.Rolls-Royce is taking a break from manufacturing after customer Airbus SE also paused production to check on measures to protect employees from Covid-19. Boeing Co. has gone a step further, winding down planemaking in the Seattle area for two weeks after a worker died of virus-related complications.China Ramps Up Stimulus Measures (8 a.m. NY)China will appropriately raise its fiscal deficit as a share of gross domestic product, issue special sovereign debt and allow local governments to sell more infrastructure bonds as part of a stimulus package to stabilize the economy, according to a politburo meeting on Wednesday, central China television reported late on Friday.Italy Virus Curve Seen Flattening Slightly (7:49 a.m. NY)The curve of new coronavirus cases in Italy appears to have started flattening slightly since March 20, Silvio Brusaferro, head of the countrys National Health Institute, said at a press conference on Friday. The mortality rate in the country is proportional to patients age, Brusaferro said.The National Health Institute said the country wasnt at the peak of the contagion yet, but the head of the Superior Health Council Franco Locatelli said there were clear signs that the containment measures are efficient, so people must respect them.Italy reported its biggest rise in coronavirus infections in the last five days on Thursday, as the disease spread further in the northern Lombardy region, even after weeks of rigid lockdown rules.For more articles like this, please visit us at bloomberg.comSubscribe now to stay ahead with the most trusted business news source.2020 Bloomberg L.P.

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