Daily Archives: March 28, 2020

From Bats to Human Lungs, the Evolution of a Coronavirus – The New Yorker

Posted: March 28, 2020 at 1:42 pm

There are endless viruses in our midst, made either of RNA or DNA. DNA viruses, which exist in much greater abundance around the planet, are capable of causing systemic diseases that are endemic, latent, and persistentlike the herpes viruses (which includes chicken pox), hepatitis B, and the papilloma viruses that cause cancer. DNA viruses are the ones that live with us and stay with us, Denison said. Theyre lifelong. Retroviruses, like H.I.V., have RNA in their genomes but behave like DNA viruses in the host. RNA viruses, on the other hand, have simpler structures and mutate rapidly. Viruses mutate quickly, and they can retain advantageous traits, Epstein told me. A virus thats more promiscuous, more generalist, that can inhabit and propagate in lots of other hosts ultimately has a better chance of surviving. They also tend to cause epidemicssuch as measles, Ebola, Zika, and a raft of respiratory infections, including influenza and coronaviruses. Paul Turner, a Rachel Carson professor of ecology and evolutionary biology at Yale University, told me, Theyre the ones that surprise us the most and do the most damage.

Scientists discovered the coronavirus family in the nineteen-fifties, while peering through early electron microscopes at samples taken from chickens suffering from infectious bronchitis. The coronaviruss RNA, its genetic code, is swathed in three different kinds of proteins, one of which decorates the viruss surface with mushroom-like spikes, giving the virus the eponymous appearance of a crown. Scientists found other coronaviruses that caused disease in pigs and cows, and then, in the mid-nineteen-sixties, two more that caused a common cold in people. (Later, widespread screening identified two more human coronaviruses, responsible for colds.) These four common-cold viruses might have come, long ago, from animals, but they are now entirely human viruses, responsible for fifteen to thirty per cent of the seasonal colds in a given year. We are their natural reservoir, just as bats are the natural reservoir for hundreds of other coronaviruses. But, since they did not seem to cause severe disease, they were mostly ignored. In 2003, a conference for nidovirales (the taxonomic order under which coronaviruses fall) was nearly cancelled, due to lack of interest. Then SARS emerged, leaping from bats to civets to people.The conference sold out.

SARS is closely related to the new virus we currently face. Whereas common-cold coronaviruses tend to infect only the upper respiratory tract (mainly the nose and throat), making them highly contagious, SARS primarily infects the lower respiratory system (the lungs), and therefore causes a much more lethal disease, with a fatality rate of approximately ten per cent. (MERS, which emerged in Saudi Arabia, in 2012, and was transmitted from bats to camels to people, also caused severe disease in the lower respiratory system, with a thirty-seven per cent fatality rate.) SARS-CoV-2 behaves like a monstrous mutant hybrid of all the human coronaviruses that came before it. It can infect and replicate throughout our airways. Thats why it is so bad, Stanley Perlman, a professor of microbiology and immunology who has been studying coronaviruses for more than three decades, told me. It has the lower-respiratory severity of SARS and MERS coronaviruses, and the transmissibility of cold coronaviruses.

One reason that SARS-CoV-2 may be so versatile, and therefore so successful, has to do with its particular talent for binding and fusing with lung cells. All coronaviruses use their spike proteins to gain entry to human cells, through a complex, multistep process. First, if one imagines the spikes mushroom shape, the cap acts like a molecular key, fitting into our cells locks. Scientists call these locks receptors. In SARS-CoV-2, the cap binds perfectly to a receptor called the ACE-2, which can be found in various parts of the human body, including the lungs and kidney cells. Coronaviruses attack the respiratory system because their ACE-2 receptors are so accessible to the outside world. The virus just hops in, Perlman told me, whereas its not easy to get to the kidney.

While the first SARS virus attached to the ACE-2 receptor, as well, SARS-CoV-2 binds to it ten times more efficiently, Kizzmekia Corbett, the scientific lead of the coronavirus program at the National Institutes of Health Vaccine Research Center, told me. The binding is tighter, which could potentially mean that the beginning of the infection process is just more efficient. SARS-CoV-2 also seems to have a unique ability, which SARS and MERS did not have, to use enzymes from our human tissueincluding one, widely available in our bodies, named furinto sever the spike proteins cap from its stem. Only then can the stem fuse the virus membrane and the human-cell membrane together, allowing the virus to spit its RNA into the cell. According to Lisa Gralinski, an assistant professor in the Department of Epidemiology at the University of North Carolina at Chapel Hill, this supercharged ability to bind to the ACE-2 receptor, and to use human enzymes to activate fusion, could aid a lot in the transmissibility of this new virus and in seeding infections at a higher level.

Once a coronavirus enters a personlodging itself in the upper respiratory system and hijacking the cells hardwareit rapidly replicates. When most RNA viruses replicate themselves in a host, the process is quick and dirty, as they have no proofreading mechanism. This can lead to frequent and random mutations. But the vast majority of those mutations just kill the virus immediately, Andersen told me. Unlike other RNA viruses, however, coronaviruses do have some capacity to check for errors when they replicate. They have an enzyme that actually corrects mistakes, Denison told me.

It was Denisons lab at Vanderbilt that first confirmed, in experiments on live viruses, the existence of this enzyme, which makes coronaviruses, in a sense, cunning mutators. The viruses can remain stable in a host when there is no selective pressure to change, but rapidly evolve when necessary. Each time they leap into a new species, for example, they are able to hastily transform in order to survive in the new environment, with its new physiology and a new immune system to battle. Once the virus is spreading easily within a species, though, its attitude is, Im happy, Im good, no need to change, Denison said. That seems to be playing out now in humans; as SARS-CoV-2 circles the globe, there are slight variations among its strains, but none of them seem to affect the viruss behavior. This is not a virus that is rapidly adapting. Its like the best car in the Indy 500. Its out in front and there is no obstacle in its path. So there is no benefit to changing that car.

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From Bats to Human Lungs, the Evolution of a Coronavirus - The New Yorker

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IntegraGen Announces Leading U.S. Cancer Center to Use MERCURY Cloud-based Tool for Oncology Sequencing Data Interpretation and Reporting – Business…

Posted: at 1:42 pm

EVRY, France--(BUSINESS WIRE)--Regulatory News:

IntegraGen (Paris:ALINT), a company specializing in the transformation of data from biological samples into genomic information and diagnostic tools for oncology, today announced Dana-Farber Cancer Institute will utilize the companys MERCURY cloud-based software as part of their analysis and reporting process for sequencing data obtained from tumors of cancer patients. Dana-Farber plans to utilize MERCURY to assist in the analysis of sequencing data obtained from small and large targeted gene sequencing panels as well as data derived from whole exome and genome sequencing.

Genomic profiling of tumors can assist in the identification of pathogenic molecular alterations which drive a patients cancer and enable the implementation of precision medicine-based approaches to treatment, stated Annette S. Kim M.D., Ph.D., Co-Director of the Dana-Farber Cancer Institutes new Interpretive Genomics Program within the Department of Oncologic Pathology. The program is Co-Directed by Keith L. Ligon, MD PhD, Director of the Dana-Farber Center for Patient Derived Models. MERCURY provides us with a tool to rapidly interpret large scale and complex genomic sequencing data with the added ability of customization to meet our specific analysis and reporting needs to support clinical research and clinical trials.

IntegraGen is excited about Dana-Fabers decision to utilize MERCURY and look forward to interacting with another world leader in cancer care related to the utilization of our cloud-based bioinformatic tools, said Larry Yost, General Manager of IntegraGen, Inc. We are convinced that the use of MERCURY will aid in the better understanding of the etiology of a patients cancer and assist with the realization of the benefits of precision medicine by transforming large-scale sequencing data into actionable results. We are also looking forward to continuing the development and expansion of our genomic interpretation software tools in North America.

MERCURY is a user-friendly genomic interpretation tool for oncology designed to assist pathologists and oncologists to rapidly transform raw data obtained via high-throughput sequencing into a clinical molecular report for clinical and research use. The cloud-based tool minimizes the complexity, time and cost associated with the clinical interpretation and identification of variants that may be of interest in the therapeutic management of patients. MERCURY utilizes the Google Cloud technology to ensure a secure environment for data analysis and storage which is compliant with the latest information security requirements.

About IntegraGen

IntegraGen is a company specializing in the analysis of the human genome and performs adaptive and quickly interpretable analyses for academic and private laboratories. For the management of cancers, which are characterized by a genetic disruption of cells, IntegraGen provides researchers and doctors with universal and individualized therapeutic guidance tools allowing them to adapt the treatment to the patient's genetic profile.

IntegraGen has forty-six employees and generated revenue of 8.3 million in 2019. Based in the Gnopole d'Evry, IntegraGen is also located in the United States in Cambridge, MA. IntegraGen is listed on Euronext Growth in Paris (ISIN: FR0010908723 - Mnemo: ALINT - Eligible PEA-PME).

For more information, visit http://www.integragen.com

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Experts Say Mapping of Cannabis Genome Could Potentially Improve Crops And Health – Cannabis Health Insider

Posted: at 1:42 pm

To battle the COVID-19, the population is majorly relying on the health care workers. Consequently, interacting with patients suffering from a contagious virus, leaves them as the most vulnerable. 20% of the globally infected cases (1,701) during the SARS coronavirus epidemic in 2003, were health care workers.

While age is a focal risk factor for the COVID-19, health workers of any age are extremely vulnerable. Hazardous consequences of the virus do not limit itself to the individuals infected. The capacity of the health care system is incredibly affected after every case of COVID-19 in a healthcare worker.

Health workers consequently risk exposure to viral particles more than the general public, and can possibly result in worse cases. For this reason, a large number of younger Chinese doctors have died.

Moreover, with the number of patients increasing, protective equipments are facing shortage. Meanwhile, less developed parts of the worlds, have fewer and/or inadequate health care facilities, along with overburdened staff that result in exceptionally high risks. The added stress and long duty hours only increases the vulnerability of the immune systems of health workers. Eventually, hospitals turn into a hub for the transmission of COVID-19.

Numerous doctors in Wuhan died due to the COVID-19, but were the first to raise the alarm, despite being silenced by Chinese authorities.

However, many institutions can fail in providing protection to their health care workers. Two nurses IN Dallas, were infected with Ebola in 2014, and while CDC had claimed it to be a result of breach in protocol, the nurses explained how there were no established protocols in the first place. The CDC repeated this with a Californian nurse who requested a test after developing symptoms of COVID-19 after dealing with an infected patient.

China had insisted that 13 was the number of infected doctors, causing everyone to think that the spread within hospitals could be prevented by the standard protocol and was not a concern for six weeks.

However, on the day of February 14th, the number had jumped to 1,716 and by February 20th, the World Health Organization had reported 2,055 lab-confirmed COVID-19 cases among health workers only. The estimated number had come up to 3,200 by March 3rd.

On the contrary, Italy had been reporting high rates of infected health care workers. They reported about 8.5 percent of their total infected cases, to be health workers, which would be 20 percent of their health care workforce. Meanwhile in Spain, over 4,000 infected cases had been found in the health care workforce.

Unfortunately, no matter what circumstances, the risk factor, less or more, will always exist for health care workers due to the nature of their job and workplace environment. Performing certain tasks like CPR, intubation, ventilation, and resuscitation, require the worker to maintain less than a safe distance between them and the patient. Hence, the best of circumstances do not exist.

Even today, there is a shortage of N95 masks, gowns, suits, and goggles, causing an increase in risks and uncertainty for the health care workers.

A shortage of staff (either the infected victims or the ones unwilling to take substantial risks) could cause redundancy of perfect supply chains, with more beds, more hospitals etc. Even If health workers were the only one to receive vaccines, it would still lessen the risk of the collapse of the health systems. However, CEO of a vaccine company has told the financiers that a potential vaccine for the COVID-19 is expected to be available to some health workers.

When there will be no doctors to treat, and no nurses to care, the death rates will increase exponentially from COVID-19 along with the other usual killers.

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Online Gambling Laws in the USA and Europe: Here Are the Key Differences – TimesOfCasino

Posted: at 1:41 pm

Gambling has emerged a popular activity and great pastime in various parts of the world. However, there are vital regulatory differences from region to region. When it comes to the European Union, the member states become in charge of their own gambling rules and regulations. Meanwhile, a few states in the USA embrace a lenient approach towards gambling. But, a few states in the United States prevent such kind of activity. However, you will witness major controls in place levied by the federal government, which means that states may have to stick to these regulations. Some states, such as New Jersey and Nevada, have been campaigning actively for legislation and acceptance of online gambling.

The legal status of online gambling is quite mixed in the European Union. You will notice that countries like Malta, Czech Republic, Latvia, UK, Romania, Sweden, Estonia have put in place clear licensing rules.

The rules are controlled by local governments, and there are some sets of laws put in place that must be adhered to by the operators. These markets have gained the understanding that they must have transparent and competitive laws in place if they want to attract leading global operators. However, the rules are not similar for all the 28 member states available in the European Union. Some have decided to restrict online gambling licensing entirely. These nations have also turned to IP blocking and website banning in a bid to keep the international operators out.

Recently, reports have surfaced that the European Commission is trying to create a framework for online gambling in the EU.

In the case of the USA, the Supreme Court of the country paved the way for the separate states to launch legislation allowing sports betting by removing the federal law which had prohibited this earlier. The result of this announcement by the Apex Court led to a long battle by New Jersey to legalize online betting within the Atlantic City. The SCs decision did not make online betting legal in the USA, but the decision has landed the ball in the court of individual states to legalize and regulate online betting.

Now, most of the gambling laws in the USA have been set up by individual states. It implies that different states have their own different gambling laws in place. It is worth noting that the limited re-opening of the USA market led to the entries of giant companies and they established their presence in the country. A large number of these companies have effectively created exclusive websites for US bettors. The websites also underwent major developments in a bid to deliver a great experience.

We can conclude here that the future of online gambling in the USA still appears to be fragile, as some states may block online gambling. The gambling laws in the USA are reportedly more complicated than in Europe. Europe has relatively simple gambling laws.

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Covid-19, The Premier League and Online Betting – The Game Haus

Posted: at 1:41 pm

The outbreak of COVID-19 has hit the pause button on everyday life. From a natter with friends over cappuccinos at your local caf to holidays abroad, societys usual activities have stopped, and it all weighs heavy on the economy.

Elite level football has also been postponed in the UK after it emerged that Arsenal manager Mikel Arteta was confirmed to have caught the virus and in line with the UK Governments social distancing response. As the MLSand the Premier League is still on hold due to the coronavirus, betting sites in the UKare struggling to maintain their business, but its not all bad news.

Sports betting makes up a considerable portion of gambling in the UK, and the success and glamour of the Premier League is a big part of that. With the football postponed, gambling sites have been struggling to maintain typical revenue figures at these times. However, something else is happening right now that is enabling online gambling to stay busy.

Many of the typical gamblers are also staying home. And keeping in line with government advice to self-isolate and stay out of the public as often as possible. This has resulted in more time to fill while at home. And one way to fill that time is by using online betting sites for other types of gambling.

Although there is no football betting going on right now, the number of people interested in betting at online casinos may increase. This includes betting on poker, blackjack, roulette and slot games.

The Premier League was initially postponed until the first weekend in April. But that has now been moved again until June. However, it is unlikely that any professional footballer will be back on the pitch at this time. Boris Johnson stated that he wants to turn the tide within 12 weeks, but even this timeframe has come under criticism for being too short.

So, to answer the question when the Premier League will restart? How long is a piece of string

The timing of the restart will have a significant impact on how the season will be finished and if it is possible at all. Postponing the European Championshipsfor 12 monthshas helped, but here are some possible solutions to the problem:

There is also a legal complexity to the issue as some players are only contracted to clubs until June, and there are TV rights and sponsorship deals to consider as well.

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Isolation will fuel gambling addiction. We must protect those at risk – The Guardian

Posted: at 1:41 pm

In the past two weeks, life as we know it has changed immeasurably. Our new reality wont be easy to endure. Most of us will get bored and crave our old freedoms shopping, going to the pub, lounging in the park with friends as the weather warms up. While trapped inside, many of us will rely on technology to pass the time. Online learning resources will provide frazzled parents with teaching aides for their children; video calls to family and friends will assuage the loneliness for many older people.

But theres another, less inviting, aspect of technology. The effects of self-isolation countless hours with often no more company than a computer screen are also the perfect conditions for online gambling. Gambling companies have realised this and already appear to be using our newfound isolation to their own advantage. Where quarantine has meant a downturn for many businesses, gambling companies may see this period as a huge opportunity to increase their profit margins.

My inbox has been inundated with messages about targeted advertising, and offers aimed at people who usually place sports bets to trial other much more addictive casino-style games instead.

For some people, online gambling may be a welcome, fleeting distraction from the real world a momentary interruption to an otherwise monotonous day. But weve seen time and again how unscrupulous this industry can be, where money seems to matter more than customers safety and wellbeing.

The industry long resisted a stake reduction for fixed-odds betting terminals (FOBTs). Earlier this year it emerged that some companies only allowed customers to watch live matches if they opened betting accounts. Just two weeks ago, the gambling firm Betway was given a record fine for accepting stolen money from high-spending VIP customers, some displaying clear signs of addiction.

I am deeply concerned that as we move further into this crisis, greater numbers of people will turn to online gambling as a distraction. In the absence of legislation, the industry itself must act responsibly. This week I wrote to the industry and called on them to impose daily spending limits. The companies havent been receptive.

More than ever, we need online gambling companies to introduce a 2 stake for slot games, and greater controls on casino content. Such limits introduce friction slowing down the speed of play, and preventing problematic gambling. Indeed, introducing a 2 limit has dramatically reduced the harm associated with FOBTs.

Online gambling isnt regulated by the same rules that exist for machine-betting shops or arcades, where there are stake or spend limits. Sitting at home on your computer, you can spend thousands of pounds in minutes, with little, if any, restrictions.

If the industry were to impose reduced stake limits, it would demonstrate that they are willing to both protect their customers safety and exercise some moral judgment. We are all facing a period of great uncertainty. I hope the gambling industry will take the necessary steps to protect the vulnerable at a time when its needed most.

Carolyn Harris is the Labour MP for Swansea East

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‘Harm risks arising from online gambling have increased as a result of recent events’ – Yogonet International

Posted: at 1:41 pm

N

eil McArthur, CEO of the UK Gambling Commission (UKGC), wrote a public letter to online gambling firms acknowledging the impact that the response to the coronavirus outbreak has had on the industry in Great Britain and reminding operators that consumer protection "must be paramount."

According to McArthur, the Commission has been drawing up an initial assessment on the impact recent events will have on the gambling industry and "assessing how we should approach our own work over the coming months."

The social distancing measures that have been imposed this week in Great Britain now mean that anyone other than key workers will be at home for most of the day, and according to the UKGC, they are already seeing reports of an increase in online slots, poker, casino gaming, and virtual sports.

As a result of these recent events, risks of harm arising from online gambling have increased, McArthur says, so operators must be especially aware that protecting children and vulnerable people from being harmed by gambling needs to remain "a major priority."

As regards consumer protection, the commission said operators must be very mindful that some customers may be vulnerable and experiencing financial uncertainty, whilst others may be experiencing other effects of being isolated including, for example, feelings of anxiety, loneliness or boredom, so they are expected to "act responsibly, especially around individual customer affordability checks and increased social responsibility interactions." and "step in if they are showing signs that they are experiencing or at risk of harm."

McArthur then referred to responsible marketing, saying the commission expects operators to "onboard new customers in a socially responsible way," warning them not to "exploit the current situation for marketing purposes."

"You should be very cautious when seeking to cross-sell online gaming products to customers who signed up with you in order to bet and we expect you to ensure that your affiliates are conducting themselves appropriately."

McArthur went on explaining they expect online firms to work with the Commission in an open and co-operative way and act in accordance with "both the letter or the spirit of the regulatory framework we have set."

Finally, he warned operators that if the UKGC sees irresponsible behavior, they will step in immediately. Whilst I know that the current climate is unprecedented, gambling operators must play their part in making sure that people are kept safe.

See the full letter here.

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Talking Horses: How safe is the money in your online betting account? – The Guardian

Posted: at 1:41 pm

With all European racing and most global racing and sport likely to be suspended for many weeks as a result of the coronavirus pandemic, the Horseracing Bettors Forum, an independent body representing punters interests, has warned bookmakers customers to make sure that any money they have deposited with online bookies will be protected if the firm goes under.

HBF issued an updated version of its Register of Protection of Funds on Thursday, which highlights the surprising degree to which internet gambling firms vary in the approach to ring-fencing deposits from customers. Using the different companies own Terms & Conditions (T&Cs), HBF highlights 23 where deposits are Not Protected according to a definition supplied by the Gambling Commission, which regulates all UK gambling operators.

BetFred, one of the most familiar brands in UK betting, is typical of these. In its Terms & Conditions regarding Segregation of Funds, the firm notes that our licence from the Gambling Commission requires that we inform customers about what happens to money that we hold on account for you in the event of insolvency.

It continues: Under the current Gambling Commissions insolvency rating system your funds are not protected. Customer funds are kept in accounts separate from company accounts, but they would form part of the assets of the business in the event of insolvency.

Other firms where funds are defined as Not Protected include the Tote, Marathon Bet, SportNation and BetHard, whose prices often feature on the popular odds-comparison site Oddschecker.

While many punters may be astonished to discover that the Gambling Commission allows deposits to be seen as part of a bookmakers assets for insolvency purposes, HBF also points out that eight firms fulfil the GCs definition of a High level of protection for funds: Betfair (Sportsbook and Exchange), BetStars, BetVictor, Betway, Coral, Paddy Power and Smarkets, a betting exchange. As Betfairs T&Cs confirm, in the unlikely event that Betfair becomes subject to any insolvency proceedings, then your money will not be available to administrators/liquidators and so you will be able to withdraw your money from your account as normal.

The remaining 33 firms on HBFs list meet the Gambling Commissions definition of Medium protection for funds, under which deposits are held in a separate account but the company offers no absolute guarantee that all funds will be repaid.

In these extraordinary times, each day the coronavirus crisis continues, the likelihood of bookmakers going bust increases, Colin Hord, the HBFs chair, said on Thursday.

For some bettors, this could mean that their hard-earned money is lost for good. While we can do all we can to urge bettors to reduce or move their funds to an account that offers High Protection, we believe that in this day, bookmakers should no longer be stating on their terms and conditions that there is no guarantee their funds will be returned.

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This Week in Gambling: Online gambling explosion in the US? – Casino City Times

Posted: at 1:41 pm

With casino floors and sportsbooks being the type of areas where diseases can be freely communicated, gaming analyst and CEO of SpringOwl Asset Management Jason Ader said the industry may expedite acceptance of full mobile and online platforms for sports betting, casino, poker and bingo in the United States. In fact, if you are a licensed, land-based operator, now's the perfect time to consider online gambling.

Imagine MGM and Caesars directly targeting their customers right now with online gambling offers to play at home during the pandemic. They could even offer them the opportunity to come to Vegas with discounted rates at some point in the future. In New Jersey, Pennsylvania, Nevada and Delaware, where sports betting, casino, poker or some combination of all three can be played from the relative safety of a living room via computer or mobile device, impacts could be mitigated if such a retail shutdown became necessary. Or if consumer unease continues to fester as more COVID-19 cases are identified.

Proposed online gambling expansion in Florida could help that states and others considering sports betting legislation to accelerate the shift to digital. Its becoming clear that online gambling could increase tax revenue like in New Jersey and Pennsylvania.

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Online Gambling & Betting Market 2020 | Growing Rapidly with Significant CAGR, Leading Players, Innovative Trends and Expected Revenue by 2026 -…

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New Jersey, United States:The Online Gambling & Betting Market is carefully researched in the report while largely concentrating on top players and their business tactics, geographical expansion, market segments, competitive landscape, manufacturing, and pricing and cost structures. Each section of the research study is specially prepared to explore key aspects of the Online Gambling & Betting market. For instance, the market dynamics section digs deep into the drivers, restraints, trends, and opportunities of the Online Gambling & Betting Market. With qualitative and quantitative analysis, we help you with thorough and comprehensive research on the Online Gambling & Betting market. We have also focused on SWOT, PESTLE, and Porters Five Forces analyses of the Online Gambling & Betting market.

Global online gambling & betting market was valued at USD 49.63 Billion in 2018 and is projected to reach USD 114.38 Billion by 2026, growing at a CAGR of 10.94% from 2019 to 2026.

Leading players of the Online Gambling & Betting market are analyzed taking into account their market share, recent developments, new product launches, partnerships, mergers or acquisitions, and markets served. We also provide an exhaustive analysis of their product portfolios to explore the products and applications they concentrate on when operating in the Online Gambling & Betting market. Furthermore, the report offers two separate market forecasts one for the production side and another for the consumption side of the Online Gambling & Betting market. It also provides useful recommendations for new as well as established players of the Online Gambling & Betting market.

Online Gambling & Betting Market by Regional Segments:

The chapter on regional segmentation describes the regional aspects of the Online Gambling & Betting market. This chapter explains the regulatory framework that is expected to affect the entire market. It illuminates the political scenario of the market and anticipates its impact on the market for Online Gambling & Betting.

Analysts who have authored the report have segmented the market for Online Gambling & Betting by product, application and region. All segments are the subject of extensive research, with a focus on CAGR, market size, growth potential, market share and other important factors. The segment study provided in the report will help players focus on the lucrative areas of the Online Gambling & Betting market. The regional analysis will help the actors to strengthen their position in the most important regional markets. It shows unused growth opportunities in regional markets and how they can be used in the forecast period.

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Highlights of TOC:

Overview: In addition to an overview of the Online Gambling & Betting market, this section provides an overview of the report to give an idea of the type and content of the study.

Market dynamics: Here the authors of the report discussed in detail the main drivers, restrictions, challenges, trends and opportunities in the market for Online Gambling & Betting.

Product Segments: This part of the report shows the growth of the market for various types of products sold by the largest companies.

Application segments: The analysts who have authored the report have thoroughly evaluated the market potential of the key applications and identified the future opportunities they should create in the Online Gambling & Betting.

Geographic Segments: Each regional market is carefully examined to understand its current and future growth scenarios.

Company Profiles: The top players in the Online Gambling & Betting market are detailed in the report based on their market share, served market, products, applications, regional growth and other factors.

The report also includes specific sections on production and consumption analysis, key results, key suggestions and recommendations, and other issues. Overall, it offers a complete analysis and research study of the Online Gambling & Betting market to help players ensure strong growth in the coming years.

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