Opinion: UBC erases boundaries between engineering and health – Vancouver Sun

Posted: August 22, 2017 at 11:54 pm

Mark Ansermino, left, and Guy Dumont were working on a device in 2005 to aid people monitoring patients during surgery. Ward Perrin / Vancouver Sun

A deceptively simple device invented at the University of B.C. is saving lives in the worlds most impoverished places.

Called the Phone Oximeter, it clips onto a persons fingertip and is connected by wire to a smartphones audio port. By measuring blood-oxygen levels and heart and breathing rates with unprecedented simplicity, portability and affordability, its enabling easier diagnosis of illness in Mozambique, Pakistan and Uganda.

How it came to be at UBC reveals the magic of universities.

Fifteen years ago, electrical engineer Guy Dumont, an expert in creating intelligent automated systems, met Mark Ansermino, an anesthesiologist who wanted to improve measurement of vital signs during surgery. From that first encounter between two complementary faculty members, a string of inventions followed.

The Phone Oximeters genesis at a university was no accident. UBC, like so many of its peer institutions, attracts experts in diverse fields. Brought together into a larger community, they sometimes share ideas and wind up doing things they could never achieve or even dream of achieving on their own.

But when that lightning does strike, its often by accident or the result of occasional get-togethers. If only we could make such interactions a regular feature on our campuses, imagine the ingenuity that would spring forth.

Now we are now doing just that, with UBCs latest creation: a school of biomedical engineering.

This new cluster of faculty and students, a joint venture of the faculties of medicine and applied science, will break down antiquated academic boundaries. We want to replicate many times over the genius of the Phone Oximeter applying an engineering mindset to disease prevention, diagnosis and treatment.

That could mean medical devices like the Phone Oximeter. But it also means extending engineering into realms that most people have a hard time grasping: the splicing of genes, the rearrangement of proteins and the cultivation of stem cells, which can be coaxed into repairing or even replacing damaged tissues or organs.

This is a squishier world than many engineers are used to. But its governed by the same physical principles that all engineering students must master. And its just as yielding to their quantitative approach and creative design skills, which offer new solutions to societys major health challenges, including cancer, neurological disease, cardiovascular disease and diabetes.

UBC is the first university in Western Canada to recognize the importance of this burgeoning field with a school of its own. And we are doing it at a propitious time, as B.C. diversifies its resource-based economy by cultivating a vibrant tech sector, and as the province joins the University of Washington in creating the Cascadia Urban Analytics Cooperative, emulating the success of such regional tech hubs as Silicon Valley, North Carolinas Research Triangle and Bostons Route 128 Corridor.

To fulfil even part of that tech-based vision, higher education must position itself several steps ahead by preparing students to readily enter that economy from the moment they graduate, and to play leading roles in both established companies and new ventures. Playing catch-up isnt an option we need to cultivate the talent now or risk having that vision wither for lack of local talent.

The Phone Oximeter, invented at the University of B.C., clips onto a persons fingertip and is connected by wire to a smartphones audio port. By measuring blood-oxygen levels and heart and breathing rates with unprecedented simplicity, portability and affordability, its enabling easier diagnosis of illness in Mozambique, Pakistan and Uganda. Handout / PNG

Clearly, there is a demand for such training. The faculty of applied science started offering masters degrees and doctorates in biomedical engineering a mere seven years ago, and applications have increased steadily to almost 200 in 2016.

The new school will provide those students expected to number about 90 this year with a distinct, high-profile home, signalling to future students our commitment to be a leader in this field. In the years ahead we hope to extend the talent pipeline even further by offering bachelors degrees in biomedical engineering as well.

That higher profile will also help attract the most promising or sought-after biomedical engineering faculty. In fact, it already has: Peter Zandstra, most recently of the University of Toronto, has joined UBC to become the schools first director.

Zandstra wont need much help finding his way around he spent five years at UBC earning his doctorate in biotechnology and chemical engineering. But we recruited him for his ingenuity in growing stem cells, his mathematical modelling to predict how stem cells behave and how they can be controlled, and his success in generating human tissue for drug testing or treatment. On top of all that, he has proven leadership skills, honed from his experience steering large academic research groups and startup companies.

Joining him in the months and years ahead will be seven other new faculty members, along with 20 current faculty members jointly appointed from their current departments, including electrical engineer Tim Salcudean, who has proudly ignored the obsolete divisions that once separated him from his medical colleagues.

Salcudean is advancing two innovations that have already transformed patient care: magnetic resonance imaging (MRI) and ultrasound. He is making those technologies more revealing by bringing digital analysis to images that are now mostly eyeballed. He is also making them more useful by superimposing MRI and ultrasound images onto magnified images of a surgical field, so surgeons can see underneath the tissue on which theyre operating, and thus spot patches of cancer that would normally be hidden.

These arent an academics theoretical musings. Thanks to UBCs partnerships with the provinces health system, Salcudean has been able to team up with UBC urologist Peter Black to successfully test ultrasound and MRI image-guided techniques on 27 patients with prostate cancer. Based on those results, there are plans for more.

We cant simply leave those kinds of advances to the random happenstance of the occasional symposium or accidental meeting. The stakes in terms of lives saved or quality of life are too high.

Our new school of biomedical engineering will bring health scientists, clinicians and engineers together on a daily basis and provide them with the space and the tools to collaborate. Just as important, it will bring graduate students and medical students into that collaboration to learn from it, emulate it and, we hope, take it in directions that we havent yet imagined.

Dermot Kelleher is dean of the faculty of medicine and James Olson is interim dean of the faculty of applied science at the University of B.C.

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