Category Archives: Psoriasis

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There is a uniquely American phenomenon anyone living in or visiting the states is familiar with: A commercial full of happy, smiling people appears on television. A narrator declares that a brand-name drug is changing the lives of people with, say, psoriasis. A faster voice runs down a list of potential side effects of the drug while the actors keep smiling and laughing, maybe dancing (for some reason). The narrator returns with a clear directive: Talk to your doctor today about [the medication].

The thing is, though, that talking to your doctor about medication can be kind of fraught, especially if you plop down in the exam room with a brand name you heard on TV, but no real clue what its all about. Is that how this is supposed to work? Theyre the one with years worth of education and experience, after all. Is it OK for you to suggest to them that you want medication?

It is OK, but there are no guarantees youll get the medication. That might be OK, too. Lets go over how you can talk to your doctor about medication options.

If you are having symptoms and did your own research, you might worry that a doctor will be dismissive of you if you bring up your interest in medication, since youre not, well, a doctor. To be clear, they might bedoctors are human and bias in healthcare is definitely a thingbut there is no reason you shouldnt advocate for yourself. You might not be a medical expert, but you are the expert on your own body.

Dr. Yoni Freedhoff, associate professor of family medicine at the University of Ottawa, said hes noticed patients can be cautious about suggesting to doctors that they have a medication that they think they should be on or theyd like to try. That can come from negative experiences with healthcare providers in the past or a feeling of sheepishness about coming out and saying they think they need medication.

Dr. Joseph Thomas, a hospitalist in New York, agreed that there certainly is some hesitancy at times because they dont want to come off as pushy, like theyre being demanding ... but I think if patients are curious or if they have questions, if theres something they would like to ask about being started on, then yes, absolutely bring that up.

The bottom line, Freedhoff said, is this: If a person has a desire to discuss something with their doctor, regardless of what that thing is, ideally, they should be able to have that discussion with their doctor. A doctors job is pretty straightforward. Our job is to inform people about their treatment options and the risks and ramifications of doing things and not doing things, but never to judge people on the treatment they decide for themselves.

The doctors job is to listen to your concerns and answer your questions, so you have every right to share them.

Did anyone ever tell you, God answers all our prayers, just not always with a yes? Doctors can be kind of like that (but theyre not God). They dont get to make executive decisions about your treatment andalso unlike Godthey are available for follow-up questions when they give you a no.

There will definitely be times where people will bring up medications that are not necessarily appropriate, Freedhoff said. Youre not a doctor, so you might not know that a certain medication wont work for your symptoms or isnt advisable at this point in your treatment. You might not realize you dont meet the clinical criteria for a certain prescription or your insurance wont cover it. Thats fine; youre not the doctor here, so how could you know? The doctors job in this situation is to explain all of that to you. A good doctor, Freedhoff said, would be able to explain thathopefully in a way that doesnt upset the patient.

If the doctor says you dont meet the clinical criteria, ask why not and ask about what options exist that you do qualify for. Freedhoff recommended asking what criteria are utilized in determining a medications appropriateness, for instance, and Thomas pointed out that a doctor might have insight they can share about your particular tolerances. At the heart of any visit to the clinic are your health, your body, and your life. You should feel empowered to ask as many questions as it takes until you have a solid understanding of your treatment.

Were not saying you should hop from doctor to doctor until you find someone who agrees with your self-diagnosis, but you can absolutely consult someone else, provided there are doctors in your area who are available to you.

Seeking a new doctor could be a solution to a number of problems beyond the fact that your current one isnt prescribing a certain medication. As Freedhoff said, If you have a doctor and you do not feel comfortable bringing up a discussion around medication or treatment options, that should be a sign that you need to either discuss your relationship with your doctor and discuss the fact that you dont feel comfortable, try to explore why, and get past that, or get a new doctor.

Thomas added, Ive unfortunately heard too many stories of patients kind of being dismissed by their doctors, [saying things like] Oh, thats why you shouldnt go to Dr. Google and that sort of thing. That happens, and its a thing I think myself and other folks in my profession should discourage. If people are bringing up these questions, its usually because they want to be engaged in their own health and they want to do the best they can to be better and to feel better.

See? There are doctors out there who want to talk and listen. You should feel confident in sharing the truth about your symptoms and what youre going through, no matter what treatment option you decide on. If a doctor is dismissive, wont answer your questions, or shows any signs of bias, you should always feel free to look elsewhere.

All of that being said, have reasonable expectations here. In an instance where youre being treated poorly or a doctor is being very dismissive, sure, push back and advocate for yourself, but use your judgment. If a doctor is telling you youre not a candidate for something and seems willing to have ongoing conversations about what could work for you, hear them out.

Is there bias in healthcare? No question, said Freedhoff, but there will be times a drug just doesnt work for you, and that wont be due to bias. Respecting the fact that there are clinical criteria for prescription medications is worthwhile.

Remember that, as weve established, doctors arent Godbut they do have training and insights most patients dont. Thomas pointed out, for example, that while the media raised significant awareness of monoclonal antibodies as part of a treatment for COVID-19, patients may not realize those dont work as well on the latest variants. There is a lot you can find out through your own investigations, and while you should feel empowered to bring all of that up, be open to learning new things from doctors, who have more expertise here than the average journalist or marketing person.

Its worth having these discussions because medical care, at this point, is a team effort between doctor and patient, he said. Its not the paternalistic relationship that it once was decades ago. So, it cant hurt to ask.

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Is It Ever Worth Asking Your Doctor About a Medication You Saw on TV? - Lifehacker

People with atopic dermatitis, commonly known as eczema, may find that inflammation of the skin is just one of the health conditions theyre living with.

Dermatologists have been aware of an association between eczema and other health concerns. Now, after evaluating data from numerous studies, the American Academy of Dermatology (AAD) has produced an official guideline, which was released at the beginning of the year.

The analysis, published in the Journal of the American Academy of Dermatology in January, found strong evidence tying atopic dermatitis in adults to a number of diseases and conditions, including hay fever, asthma, and food allergies; alopecia (sudden hair loss) and chronic urticaria (hives); osteoporosis; mental health disorders like depression; and skin infections.

When it comes to substance abuse disorder, ADHD (attention deficit hyperactivity disorder), and metabolic syndrome (a group of five conditions that can lead to heart disease, diabetes, stroke, and other health problems), study authors identified some evidence linking these issues to eczema.

The report also suggested a link between atopic dermatitis and various cardiovascular issues, but this association was considered to be small. Evidence supporting a link between eczema and autism spectrum disorders, heart attack, and stroke was inconclusive.

The lead author of the guideline,Dawn Davis, MD,a dermatologist at the Mayo Clinic, calls the AAD guideline groundbreaking because its the first paper of its kind to give a comprehensive review of how eczema may be related to these other physical and mental problems.

We are realizing more and more that inflammatory skin disease such as atopic dermatitis and psoriasis are not only skin conditions, but rather affect the entire person, says Dr. Davis. So we need to practice whole-person care. This guideline is created to empower patients, and to empower the medical community to help patients better address their skin needs.

For decades, dermatologists have recognized a connection between eczema and other atopic and allergic conditions. (The word atopic itself indicates an association with allergies.) MedlinePlus says that up to 60 percent of people with atopic dermatitis develop asthma or hay fever (allergic rhinitis) later in life, and up to 30 percent have food allergies.

Eczema can often signal the beginning of a progression of allergic diseases known as atopic march or allergic march. After people develop eczema, a typical pattern is for them to develop food allergies, followed by hay fever and then asthma.

This new AAD guideline found that about a quarter of adults with eczema had asthma, and they were three times more likely to have this inflammation of the airways than the general population.

The research also spotlighted evidence suggesting that asthma in children ages 7 to 11 was linked to a more persistent type of eczema. Targeted biologic therapies such as dupilumab (Dupixent) demonstrated a potential benefit for both severe atopic dermatitis and asthma.

Dupilumab has been approved for asthma and eczema because both of these diseases kind of work through the same pathway and cause inflammation, says Karan Lal, MD,the committee chair for the Society for Pediatric Dermatology. Its possible if were treating eczema with dupilumab at a very early age, we may prevent [children] from developing clinical signs of asthma.

When it comes to food allergies, researchers estimated that just over 1 in 10 individuals with eczema were likely to have this condition. While the researchers were unclear as to what the implications may be, they pointed out that patients often ask whether food allergies are a trigger for their eczema and whether they should seek out testing for food allergies.

The AAD team observed a consistent link between allergic rhinitis (hay fever) and eczema but little data showing a relationship to allergic conjunctivitis (inflammation of eye tissue) and eosinophilic esophagitis (inflammation of the esophagus).

We always suspected and knew in practice that asthma, food allergies, and other atopic diseases such as allergic rhinoconjunctivitis were more common in patients with eczema, but now we have research data to support those conclusions, says Davis.

Davis stressed that the study confirmed that certain skin diseases are more common in atopic dermatitis patients, such as alopecia areata an autoimmune disease in which the immune system attacks hair follicles, causing sudden hair loss that often results in bald patches on the head and that can affect the hair on other parts of the body as well.

The guideline presented data demonstrating a strong association between eczema and the autoimmune condition chronic urticaria (hives).

Overall, if you have eczema, youre 2.5 times more likely to have an autoimmune condition, according to the new guideline.

An analysis that pooled four studies, including 11,244 adults with eczema and 149,713 people without the condition, found that individuals with eczema faced double the odds of self-reported or clinician-diagnosed depression. In addition, researchers found that eczema patients were more likely to consider suicide, but evidence linking the condition to actual death by suicide was weak.

As to why these patients may be more apt than the general public to have mental health issues, the AAD panel believes that itching, poor sleep, and decreased quality of life overall may play an extensive role.

Although some research made a connection between substance abuse and eczema, evidence was limited about any tie between the skin condition and alcohol use or cigarette smoking.

Davis and her collaborators underscored that ADHD and autism spectrum disorders are better studied in children rather than adults, and these connections will be explored more in depth in an upcoming pediatric guideline.

Atopic disease patients have increased levels of blood proteins connected with cardiovascular risk.

Because systematic inflammation is an established risk factor for cardiovascular disease, its possible that treatments that manage inflammatory skin diseases like eczema could decrease the likelihood of heart problems, according to the guideline.

But in general, the research found only a slight link between eczema and hypertension, peripheral and coronary artery disease, congestive heart failure, and events such as myocardial infarction and cardiovascular death.

The data suggested a small association between eczema and obesity and dyslipidemia (an imbalance of lipids such as cholesterol). Still, pooled facts from eight cross-sectional studies revealed that eczema patients were 36 percent more likely to be obese and 13 percent more likely to have high cholesterol than the general population.

The guideline authors pointed out that atopic dermatitis may actually have an inverse relationship with diabetes, with some research suggesting that individuals have a lower risk of diabetes overall and type 2 diabetes specifically. Based on data analyzed in this paper, however, Davis emphasized that patients with eczema may face a greater likelihood of metabolic syndrome as a whole.

Davis and her team highlighted an investigation demonstrating an increased risk of osteoporosis among those with eczema, and a separate study showed a heightened likelihood of bone fracture. For those with severe atopic dermatitis, the possibility of fracture due to osteoporosis was even greater.

Investigators noted that more research is needed to understand the mechanisms behind this association, but some explanations suggest that chronic systemic inflammation may have a negative effect on bone metabolism, leading to increased bone loss.

The connection between eczema and staphylococcal skin infections is well known. The guideline spotlights a study from the United Kingdom indicating that herpes superinfection is twice as common among those with eczema. Other data suggested cutaneous infections, bacterial skin infections, and eczema herpeticum (a painful, blistering rash caused by the herpes simplex virus) are all more likely to occur among people with eczema.

While Golara Honari, MD, a dermatologist with Stanford Medicine, sees the value in raising awareness about eczemas link to other diseases, she believes patients and doctors need to interpret these correlations with caution.

We need to learn more about these conditions in relation to atopic disease, says Dr. Honari, using cardiovascular disease as an example. There are other common skin diseases for example, psoriasis that have really solid evidence for increased risk of cardiovascular disease, but for atopic dermatitis, that evidence is still not very solid.

Were putting together associations, but we have to be careful, because I don't think these associations necessarily lead to clinical correlations, adds Dr. Lal. Do the results in the guideline mean that for patients that come in, I have to screen all my patients for metabolic syndrome because they have a diagnosis of eczema? It doesn't really work like that.

Overall, Davis and her colleagues view the new guideline as a tool to educate and empower and not induce fear.

When we know certain diseases are interrelated, then we can work on monitoring for those diseases and screening for them, and we can work on lifestyle modification factors that can alter the risk of a disease course, she says.

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Eczema Linked to Potential for Other Health Problems - Everyday Health

The new report by Expert Market Research titled, Global Psoriasis Treatment Market Report and Forecast 2021-2026, gives an in-depth analysis of the globalpsoriasis treatment market, assessing the market based on its segments like drug classes, types, routes of administration, distribution channels, andmajor regions. The report tracks the latest trends in the industry and studies their impact on the overall market. It also assesses the market dynamics, covering the key demand and price indicators, along withanalyzingthe market based on the SWOT and Porters Five Forces models.

Request a free sample copy in PDF or view the report summary@https://www.expertmarketresearch.com/reports/psoriasis-treatment-market/requestsample

The key highlights of the report include:

Market Overview (2016-2026)

The global market for psoriasis treatment is being driven by the rising incidences of psoriasis making it a critical global issue, hence augmenting the demand for an effective treatment. According to the World Health Organisation, the reported prevalence of psoriasis in countries range from between 0.09% to 11.4%. Thus, robust investments towards the development of advanced treatment to control the spread of psoriasis disease is aiding the market growth of psoriasis treatment.

Industry Definition and Segmentation

Psoriasis refers to a common inflammatory condition in which skin cells build up and form scales and itchy, dry patches. Treatment such as topical ointments, light therapy, and medication aims to remote scales and stop the robust growth of skin cells.

Explore the full report with the table of contents@https://www.expertmarketresearch.com/reports/psoriasis-treatment-market

On the basis of drug class, the market can be divided into:

Based on type, the market can be categorised into:

The market, based on administration, can be segmented into:

On the basis of distribution channel, the market can be classified into:

The regional markets for the product include:

Market Trends

The growth in the global market for psoriasistreatmentis being driven by the unawareness regarding the origin of the disease. As a result, robust research and development (R&D) about the cause, potential effects, and effective treatments is expected to have a significant influence over the growth of the market. In addition to this, favourable government measures such as reimbursement schemes, subsidised treatments, and other thoughtful measures are also expected to boost the market growth. A combination of topical and systematic therapies to reduce the effects of psoriasis in a lifelong treatment, aimed at remission, is thus driving the growth of the market.

Latest News on Global Psoriasis Treatment Market@https://www.expertmarketresearch.com/pressrelease/global-psoriasis-treatment-market

Key Market Players

The major players in the market are AbbVie Inc., Novartis AG, Johnson and Johnson Services, Inc., Pfizer Inc., and Merc and Co., Inc., among others. The report covers the market shares, capacities, plant turnarounds, expansions, investments and mergers and acquisitions, among other latest developments of these market players.

About Us:

Expert Market Research is a leading business intelligence firm, providing custom and syndicated market reports along with consultancy services for our clients. We serve a wide client base ranging from Fortune 1000 companies to small and medium enterprises. Our reports cover over 100 industries across established and emerging markets researched by our skilled analysts who track the latest economic, demographic, trade and market data globally.

At Expert Market Research, we tailor our approach according to our clients needs and preferences, providing them with valuable, actionable and up-to-date insights into the market, thus, helping them realize their optimum growth potential. We offer market intelligence across a range of industry verticals which include Pharmaceuticals, Food and Beverage, Technology, Retail, Chemical and Materials, Energy and Mining, Packaging and Agriculture.

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*We at Expert Market Research always thrive to give you the latest information. The numbers in the article are only indicative and may be different from the actual report.

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Global Psoriasis Treatment Market To Be Driven By Robust Research And Development (R&D) For The Development Of An Effective Treatment Method In The...

"With Facet, Thirty Madison will fundamentally shift how we approach skin health by actually looking through a medical lens to solve medical skin concerns, versus focusing on what often feels like these unachievable beauty standards. People need medical solutions to properly treat their skin it's the body's largest organ," said Facet Medical Director Dr. Peter Young, board-certified dermatologist. "For patients with conditions like psoriasis or eczema, every product they use plays an important role in managing their condition from their daily face wash and moisturizer to an oral treatment or an injectable and finding the right mix of treatments is critical to achieving healthy skin."

Facet will treat eczema, psoriasis, acne, rosacea, dandruff, melasma, and anti-aging. Thirty Madison's care model will offer Facet patients specialty-level care, personalized treatment, and ongoing condition management. The unique care model, paired with clinically backed treatments across a breadth of conditions, ensures patients can access their treatment right at home, whenever they need it. Treatments include prescription topicals, custom prescription formulas, prescription orals and biologics, and/or non-prescription options. Facet is Thirty Madison's first offering to provide systemic treatments and lab testing on a case-by-case basis for patients with severe psoriasis or atopic dermatitis.

"Conditions like eczema, psoriasis, and rosacea often go untreated and even for those who do receive a diagnosis, people still feel like it's a battle to manage these conditions long-term. You're left to figure it out on your own," said Rajani Rao, General Manager for Facet. "Patients deserve an empathetic, thoughtful approach led by medical experts who can offer them the holistic care plans they need to feel confident again. We've built that experience with Facet, and made it accessible, personalized, and genuinely supportive."

More consumers are looking to telehealth for their skin concerns. The average wait time to receive an in-person dermatology appointment is 32 days. During the pandemic, telehealth for dermatology usage skyrocketed by 188% from 2019 to 2022. Of U.S. consumers who accelerated their digital health/wellness engagements during the pandemic, 80% say they will continue engagements post-COVID.

Facet is the latest offering from Thirty Madison, the healthcare company whose care model powers Keeps, Cove, Evens, Picnic, and Nurx, focused on supporting patients living with chronic conditions. Thirty Madison closed its merger with Nurx last month, forming the largest and most innovative virtual care company.

About Thirty MadisonThirty Madison is the premier healthcare company for people living with chronic conditions. Thirty Madison's unique care model delivers accessible, affordable care, and superior outcomes for hundreds of thousands of patients. This specialized care model is powered by the company's proprietary platform: the technology, services, and physical infrastructure needed to provide high-quality care to an increasing number of patients. With Keeps, Evens, Cove, Picnic, Nurx, and Facet, Thirty Madison offers an extensible solution that best serves patients across the vast spectrum of chronic conditions. Learn more at ThirtyMadison.com.

SOURCE Thirty Madison

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Thirty Madison launches Facet, aims to offer the most comprehensive clinical skin health platform - PR Newswire

Morning stiffness is a common symptom for people with psoriatic arthritis (PsA).

PsA occurs when your immune system mistakenly attacks your joints and skin. Its unclear why some peoples immune systems act this way, but genes and environmental exposures may play a role.

If you have PsA, you dont have to let morning joint stiffness derail your daily routine. Here, find out why morning stiffness occurs in people with PsA and learn how to get relief.

Joint stiffness lasting 30 minutes or more is common in PsA. PsA also causes swelling in the fingers and toes.

These symptoms are often worse if youve been immobile for a period of time, such as while youre sitting or sleeping. This is why you may experience morning stiffness after being inactive all night.

This stiffness may occur in your hands, feet, or lower back. It can be on both sides of your body or only one.

Other symptoms of PsA include:

Symptoms of PsA range from mild to severe and can worsen in flare-ups. It is also possible for PsA to go into remission, in which case symptoms go away entirely for a period of time.

It may not be possible to prevent morning stiffness or joint immobility entirely, but you can take steps to reduce the severity and recover from the stiffness more quickly.

Lifestyle changes for people with PsA wont eliminate the condition. They are also unlikely to stop or reverse any flares. But they may help you cope with the effects of PsA.

Lifestyle changes aim to:

Exercise has several benefits for people with PsA. Regularly using the affected joints can help improve mobility.

Plus, exercise can boost your energy. It may also help you lose excess weight, which can reduce joint stiffness.

However, it is important to avoid irritating the joints and tendons by overworking them. Look for low impact exercise options, like biking, walking, and swimming.

Stress and tension can worsen the quality of life for people with PsA. This is because they can cause flares and make symptoms more severe.

However, you can take steps to try to relieve stress and tension and prevent these effects. For example, a brief meditation before bed may help reduce anxiety and worry while you sleep. This can help you sleep better, too.

Yoga or stretching can also help ease tension and stress. They have the added benefit of improving flexibility in the joints, which can help the joints rebound from immobility faster.

It might seem counterintuitive to sleep more when sleep is what causes your muscles to stiffen. However, when you sleep, your body naturally reduces inflammation and rejuvenates itself.

You need regular sleep and plenty of it. The recommended amount of sleep for an adult is more than 7 hours. Adequate, uninterrupted sleep may help reduce inflammation and joint stiffness all day, including in the mornings.

In addition to lifestyle changes, there are steps you can take each morning to make overcoming the stiffness easier.

You may be tempted to step into a hot shower or bath, but hot water may irritate psoriasis patches on the skin or scalp.

Instead, get heat to your stiff joints with hot packs or a heating pad. The heat helps ease muscle soreness and improve joint mobility.

Alternatively, ice packs may also help reduce joint pain or swelling.

If you have somewhere to be, give yourself extra time to wake up in the morning. Bump your alarm ahead 30 to 60 minutes, so you can recover your from morning stiffness without disrupting your routine.

To also get adequate sleep, this may mean you need to go to bed earlier.

Stretching and yoga are both good for reducing stress. Even if you dont need to relieve stress, these practices can be beneficial for your joints and mobility.

Heres one to try:

A cool bedroom is best for sleeping, but it may make your joints stiffer when you wake up. If you have a timed thermostat, set it to increase the temperature in your bedroom a few degrees a couple hours before you plan to wake up. This can help reduce stiffness.

If you have PsA, your doctor will likely prescribe medication to treat PsA. These treatments include:

In addition to these medications, your doctor may suggest supplements to reduce PsA symptoms. These include:

If you have been diagnosed with PsA, you should have regular checkups with your doctor to monitor the condition and its impact on your joint mobility and overall health.

If you notice symptoms worsening significantly or they begin to interfere with your daily life, make an appointment with your doctor.

They may be able to help you identify possible flare triggers to avoid. The doctor may also be able to adjust your medication to reduce short-term symptoms during flare-ups.

Morning stiffness is a common symptom for people with PsA. The joint stiffness and lack of mobility frequently happens after sitting or sleeping for several hours or more.

PsA can be difficult to treat, and symptoms may worsen rapidly. There is no singular universal treatment for PsA, and your treatment may change depending on how well your symptoms are managed and how frequently you experience flares.

Lifestyle changes and medication can help reduce the effects of morning stiffness, so you can recover more quickly and get your day going.

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Psoriatic Arthritis Morning Stiffness: Tips and More - Healthline

Market Dynamics of the Global Psoriasis Drugs Market: Understanding the segments helps in identifying the importance of different factors that aid the market growth.

The statistics highlights the numerous factors which are primary purpose for the short-paced enlargement of the Psoriasis Drugs Market. The facts include a look at the pricing history of the product and retail pricing that is in offering in current scenario to better understand primary reason behind demand and supply. In addition to the price of the goods or the offerings, various developments to study supply chain and production volume is closely examined in the file moreover embody the influential mounting of the population at the global degree. In addition to it, the product additionally researches the impact of the several projects of the government in the forecast duration.

While global mega trends influencing the market routing the primary direction of growth, regional markets are swayed by more granular locally unique market drivers. The market study is sized with regional and country level break for historical and forecast period by revenue and volume and price analysis, stay tuned with the latest updates from the research insights know more which territory is stealing market share gains in coming years.

Major Geographies Covered: North America Country (United States, Canada), South America, Asia Country (China, Japan, India, Korea), Europe Country (Germany, UK, France, Italy) & Other Country (Middle East, Africa, GCC) etc.

***Sub Regions Included: North America [United States, Canada, Mexico], Asia-Pacific [China, India, Japan, South Korea, Australia, Indonesia, Malaysia, Philippines, Thailand, Vietnam], Europe [Germany, France, UK, Italy, Russia, Rest of Europe], South America [Brazil, Argentina, Rest of South America], Middle East & Africa [GCC Countries, Turkey, Egypt, South Africa, Rest of Middle East & Africa]

The document also tends of inculcating the information of the profiling of the several distinguishable vendors which have been prevailing in the international marketplace of Psoriasis Drugs. The analysis additionally has a tendency of talk me about the numerous strategies that have been adopted by using numerous market place game enthusiasts for the gaining of the competitive side over the friends and inside the boom of the reach in the worldwide marketplace.

Top Players in the Market are:

AbbVie Inc., Amgen Inc., Johnson & Johnson, Novartis AG, Eli Lilly & Company, AstraZeneca, Celgene Corporation, UCB, Merck, Boehringer Ingelheim, LEO Pharma

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Market segments and sub-segments:

Product Type Segmentation

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Market sizing, growth & estimates considering current trends/opportunities/challengesCompetitive landscapeTechnological breakthroughsValue chain and stakeholder analysis

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Psoriasis Drugs Market with Emerging Technologies, Business Opportunity and Industry Forecast to 2030 Bloomingprairieonline - Bloomingprairieonline

Photo: Naypong Studio (Shutterstock)

Showering is one of the biggest uses of water in a typical residential home, according to the EPA. You dont want to use too much water in your shower, but you do need more than a few minutes to get fully clean. So where is the balance?

Dermatologists recommend keeping showers short. If you have skin conditions like eczema or psoriasis, hot water can be irritating, and so can soaps and other products you use in the shower. The American Academy of Dermatology recommends keeping showers under 10 minutes if you have itchy skin, and if you have psoriasis, you may want to go further and limit showers to just five minutes. (Lukewarm water is better than hot, which will also help you save energy.)

A five-minute shower doesnt mean you should stand under the showerhead for four minutes and then do a cursory lather in the last minute. Good hygiene is important; if youre getting into the shower, make sure youre washing what needs to be washed.

That may mean taking a lot more than five minutes. Those of us with long hair may need to be in there 10 to 20 minutes to wash and condition properly, and comb out the tangles (a job best done while conditioner is in wet hair), not to mention shaving our legs. Arguably some of these jobs can be done while the water is off, but if you arent willing to give up your long hot showers, perhaps you can counter the detrimental effects on your skin and the environment by taking fewer of them. One shower a week is hygienic enough for most of us, and better for our skin anyway.

A lot of shower advice out there seems to center around five minutes as the ideal shower time. But if dermatologists are okay with five to 10 minutes, and some of us need more time, perhaps we should aim for the middle of that range. Eight minutes turns out to be the average length of a shower for most of us, which means that if you can get through your next shower in seven minutes or less, you can feel like an overachiever. Five minutes? Great, Im proud of you.

When it comes to water usage, standard showerheads use 2.5 gallons per minute, but showerheads with the WaterSense label all use 2.0 gallons per minute or less. So you can shower for 6.2 minutes with a low-flow head and use as much water as someone showering for five minutes with a standard head. Since youre also using less hot water, youll also save energy.

So to benefit both your skin and the environment, get an efficient showerhead, turn down the heat, and dont spend any longer in there than you really need to.

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This Is the Ideal Amount of Time to Spend in the Shower - Lifehacker

Two abstracts presented at the 2022 American Academy of Dermatology (AAD) Annual Meeting explored the health-related quality of life (QOL) and mental health impact of psoriasis disease burden by severity and affected body region.

The health-related quality of life (HRQOL) impact of psoriasis was shown to be associated with severity of disease and location of lesion manifestations, according to findings of 2 abstracts presented at the 2022 American Academy of Dermatology (AAD) Annual Meeting.

As the prevalence, incidence, and morbidity of psoriasis has risen over the last 3 decades, prior research investigated the growing discussion regarding mental health and QOL in patients.

Patients with psoriasis have been shown to be at a heightened risk of depression and adverse behavioral health symptoms, in which comorbidities such as psoriatic arthritis and disease severity have been shown to exacerbate risk. The incidence of psoriasis in special areas (face, scalp, palms/soles, nails, genitals) was noted by researchers to also potentially increase disease burden.

Leveraging the multinational UPLIFT survey, a web-based survey of adults with self-reported health care providerdiagnosed psoriasis that was conducted from March 2 to June 3, 2020, they evaluated the impact of special area involvement on QOL outcomes and depression screening.1

A total of 3614 patients with psoriasis who did and did not have special area involvement were compared via Dermatology Life Quality Index (DLQI) total score and Patient Health Questionnaire-2 (PHQ-2) depression screen measurements.

Of the study cohort, 76.8% (n = 2776) had psoriasis in att least 1 special area (face, 28.1%; scalp, 53.4%; palms/soles, 24.6%; nails, 16.7%; genitals, 12.2%).

Compared with patients without special area involvement, the mean (SD) DLQI scores were shown to be higher in patients who had psoriasis in 1 or more special areas overall (9.9 [8.5] vs 7.3 [7.3]). DLQI scores were shown to be highest for those with psoriasis in the face (12.4 [8.9]), palms/soles (11.7 [9.0]), and genitals (11.7 [9.0]), followed by nails (11.6 [9.1]) and scalp (9.5 [8.4]).

Patients with involvement in 1 or more special areas were also more likely than those without special area involvement to report that their psoriasis had at least a moderate effect on QOL (DLQI 6; 57.9% vs 47.5%) and to have a positive depression screen (PHQ-2 3; 53.2% vs 44.1%).

A greater proportion of patients with psoriasis in 1 or more special areas (43.3%) had a DLQI scores of 6 or above and PHQ-2 of 3 or higher vs patients without special area involvement (32.8%).

Results of the UPLIFT survey underscore the additional QOL and psychological burdens of psoriasis for patients with special area involvement vs those without involvement in special areas, concluded the researchers.

The HRQOL impact on patients with psoriasis was further investigated by another analysis that assessed how improvements in Psoriasis Area and Severity Index (PASI) were associated with the achievement of DLQI 0/1 (no impact of skin disease on patients life).2

Pooled data from the initial 16-week periods of the BE SURE, BE VIVID, BE READY, and BE RADIANT phase 3/3b trials evaluating the use of several biologics in plaque psoriasis was included in the analyses.

Analyses included 2223 randomized patients with psoriasis who presented with a mean baseline PASI of 20.4 and a mean baseline DLQI of 10.7 (bimekizumab, n = 1362; placebo, n = 169; ustekinumab, n = 163; adalimumab, n = 159; secukinumab, n = 370).

Findings indicated that incremental PASI improvements translated to higher rates of patients achieving DLQI 0/1:

These data highlight the importance of complete skin clearance for patients with plaque psoriasis and suggest that for patients who respond to treatment, but do not achieve complete skin clearance, residual disease may still negatively impact HRQOL, said the researchers.

References

1. Langley RG, Augustin M, McBride S, et al. Impact of psoriasis in special areas on patient quality-of-life outcomes and depression screening: Findings from the multinational UPLIFT survey. Presented at: 2022 American Academy of Dermatology Annual Meeting; March 25-29; Boston, MA. Abstract 33950.

2. Blauvelt A, Lebwohl M, Gottlieb A, et al. Complete skin clearance for patients with moderate to severe plaque psoriasis: The relationship between improvements in Psoriasis Area and Severity Index and health-related quality of life. Presented at: 2022 American Academy of Dermatology Annual Meeting; March 25-29; Boston, MA. Abstract 33884.

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Psoriasis may be a skin condition, but its impact is more than skin deep. Research has shown psoriasis can increase the risk of mental and emotional issues such as depression, anxiety, low self-esteem, and loneliness.

The condition characterized by itchy, discolored patches of skin that most often develop on the knees, elbows, and scalp can cause you to feel self-conscious about exposing your skin in public, says Ahmad Amin, MD, an assistant professor of dermatology at Northwestern Medicine in Chicago. This, in turn, can prevent you from participating in activities such as going to the gym or socializing with friends, which can lead to depression or anxiety.

The physical symptoms of psoriasis can lower your quality of life as well. When someone has psoriasis, the patches on the skin can be uncomfortable painful, itchy, and troublesome, explains Dr. Amin. The skin is often very flaky, and patients can shed excess skin [leaving] flakes on their clothes, on their desk, or on the floor.

Problem is, if youve been living with psoriasis for a long time, you may not realize how much the condition is impacting your mental and emotional health. Take this short quiz to find out and learn how to deal with any challenges it reveals.

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Quiz: Is Psoriasis Affecting Your Mental and Emotional Health? - Everyday Health

The results from the scan didnt fit in with any sort of injury, or any sort of wear and tear damage, and with a few other nagging bits in my history, it meant that I was referred straight to the rheumatology team, Wilson says. Despite inconclusive blood tests, Wilson was diagnosed with rheumatoid arthritis. It wasnt until she was 28 that she had what she describes as her largest breakthroughshe moved to another part of the country and saw a new doctor. A fresh pair of eyes meant my diagnosis changed to psoriatic arthritis, and with that my treatment changed too, she says.

Unlike Parker, Wilson doesnt have skin psoriasis, which is possible (though less common) and another factor that may contribute to a delayed diagnosis. In some cases, PsA symptoms may present before the skin symptoms show up, especially in young patients, Dr. Fors Nieves adds. The skin psoriasis may also be present in less visible parts of the body, like the scalp, under the arms, or on the groin or genitals.

The first hurdle of treatment is typically finding the right specialist, which can be a struggle for some. While Parkers first rheumatologist wasnt the right fit, she eventually found a provider she felt comfortable with. I wanted someone who I could relate to and feel heard, she says. I wanted to see someone who understood a person of color may have different experiences with medical staff, and a professional who knew how to communicate with me in a way that was helpful and hopeful.

The next step is finding a treatment method that works for you. In the decade since she first saw a doctor for her joint pain and swelling, Wilson has tried several different treatments with varying levels of success. A few years ago, she underwent arthroscopic surgery to try to reduce some of the inflammation of her knee joint. Wilson says it helped for a while, but it certainly wasnt a cure. She currently manages her condition with a combination of anti-inflammatory medications, biologic injections, exercise, and sleep.

Early and mild PsA is often treated with non-steroidal anti-inflammatory drugs (NSAIDs), such as ibuprofen and naproxen. For some patients, sporadic use of these medications is sufficient to control their symptoms, Dr. Fors Nieves says. But in more severe cases, and in patients who are experiencing joint damage from the inflammation, stronger medications are often required.

In the case of a patient who is having regular flares with attacks of swollen joints and severe stiffness, we may need to add immunomodulatory medication since PsA is an autoimmune condition, says Dr. Fors Nieves. These might include conventional disease-modifying antirheumatic drugs (DMARDs), biologics, or enzyme inhibitors.

Some patients may require multiple medicines to have their skin and joint disease under control, Ronald Yglesias, MD, a rheumatologist in Aventura, Florida, tells SELF.

Managing this condition isnt just about taking medicationslifestyle changes can actually be life-changing for people with PsA. The key is listening to your body to get an idea of what it needs (or what it really needs a break from.) For instance, Wilson started to cut back on alcohol when she realized it was a major trigger for pain and stiffness the next morning.

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The Winding Road to Psoriatic Arthritis Relief - Self