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Category Archives: Transhuman News

How to live longer: DNA, wellbeing and ageing – New Zealand Herald

Posted: September 9, 2023 at 9:11 pm

Epigenetic factors regulate the genes youre born with and can cause them to malfunction, from the impact of stress, adversity and pollution to diet, exercise and whether or not you drink and/or smoke. Illustration / Getty Images

Halfway through a challenge to lower her cellular age before a significant birthday, Joanna Wane looks at how a biological clock based on data from the world-famous Dunedin Study can show whether youre speeding up or slowing down time

When Terrie Moffitt first came out from the United States to work on the Dunedin Study as a PhD graduate, the 1000-plus people whove been involved in the project since birth were in their early teens. Next year, when the latest round of exhaustive tests and interviews begins, theyll be turning 52.

Back then, in the mid-80s, a few of them were already causing minor havoc. Shoplifting at Woolworths. Converting cars. Sniffing glue in the Octagon. Drugs, alcohol, risky sex. Moffitts research over the following years into why some kids grow out of juvenile delinquency (or goofing around, as she calls it) and others grow up to be career criminals is still widely cited by criminologists worldwide.

Moffitt is now associate director of the Dunedin Study and the clear link she identified between serious adult offending and childhood trauma bears revisiting amid the current political rhetoric over getting tough on youth crime. Once they got out the other side [from their teens], we began to see those two groups diverge, she tells Canvas, from her home in North Carolina. Then you could look back and see that the ones who continued with crime into their 20s and 30s were the ones who had a lot of difficulties as very young children and grew up in very adverse homes.

The major contribution [of the research] was pointing out to governments and the justice system that the vast majority of teenagers who break the law are not going to develop into hardcore criminals, so you should really help them not get a prison record. Give them a chance to grow out of it and reform themselves and they will naturally.

What the Dunedin Study has shown over more than five decades now is that childhood exposure to poverty, trauma or victimisation leaves a lasting cellular imprint on the body, too. A tough start in life means youre likely to age faster and die earlier, you increase the risk of developing chronic age-related conditions such as cardiovascular disease, dementia, hypertension, type 2 diabetes and cancer.

Of course, the reverse is also true if youve been dealt a better hand and make the most of it, increasing your chances of an extended healthspan, defined as the number of quality years where youre generally healthy, active and free from disease.

The impact, for better or worse, of both the environment you live in and the way you behave in it holds more power over your life than you might think. Epigenetic factors regulate the genes youre born with and can cause them to malfunction, from the impact of stress, adversity and pollution to diet, exercise and whether or not you drink and/or smoke. This process of DNA methylation is the most significant influence on how well people age; some estimates put it as high as 70 to 80 per cent.

Moffitt, a professor of psychology and neuroscience at Duke University in North Carolina and a professor of social behaviour and development at Kings College, London, has remained closely involved with the Dunedin Study. Having followed the cohort from adolescence to midlife, shell be back in New Zealand next year for the latest phase of research, which will look at how well theyre preparing for old age.

Since the study members turned 26, data has been collected every five or six years on a series of key biomarkers widely used as an indicator of risk for disease, including cholesterol levels, blood pressure, gum recession, lung function, heart health and blood glucose (a potential red flag for pre-diabetes). Physical functions have been added: how long they can stand on one leg, how many times they can get up out of a chair in 30 seconds without using their hands. Brain scans, first done at age 45, will also be repeated next year.

The first epigenetic clock was invented a decade or so ago, using DNA methylation levels as a way to measure biological ageing. However, what makes the Dunedin Study so unique is its access to waves of progressive data on the same group of people. We figured out, hey, I bet we could do the same thing [as the other epigenetic clocks] but using our biomarkers, says Moffitt. So thats what we did. And we determined there were 173 of those methylation marks on top of genes that differentiated between those who were falling apart swiftly over the past 20 years, those who were holding steady and those who were staying young.

The DunedinPACE algorithm, developed in collaboration with Duke University and Columbia University in New York, analyses those epigenetic marks via a pin-prick blood test. Its now considered the most precise measure of how fast or slowly a person is ageing and the best predictor of future health outcomes. Unlike other epigenetic clocks that have been named after the scientists who invented them (Horvath, Hannum, Levine), DunedinPACE acknowledges the members of the study whove made it possible.

Likened to a speedometer, the test captures a specific moment in time and is a fluid measure that can show significant change in as little as eight weeks reflecting a lifestyle change, perhaps, or the efficacy of a new medication. The fastest rate of ageing recorded so far is 1.4, which means that a person is ageing biologically by almost five extra months for every chronological year. The slowest rate of ageing thats been measured is 0.6.

Moffitt hasnt been surprised to find such a huge variation between fast and slow agers. There are people [in the Dunedin Study] who are Olympic athletes and there are people who lead a really down-and-out life, in and out of prison, on and off addictive drugs. So I knew some were taking care of themselves and some were really not, she says. When study members came to the unit for assessment day, some would look so young while others really showed their age. Seeing that reflected in the [rate of ageing] numbers was quite amazing.

The Dunedin cohort is predominantly Pkeh but comparative studies internationally have applied the DunedinPACE algorithm successfully across ethnicities and among the elderly. Moffitt is also co-director of a longitudinal study following twins born into 1100 British families in the mid-90s and has analysed blood samples from them that show the same trajectories. Its miraculous, she says. Born 20,000 miles and 20 years apart from the Dunedin Study and yet the DunedinPACE can still tell you something about them.

Ironically, no equivalent trials have yet been done on Mori and Pasifika in New Zealand.

On my 59th birthday last November, I took a DNA Age test through Auckland-based biotechnology company SRW and sent it off to TruDiagnostics in the US for analysis. A whole swag of results came back, including my extrinsic epigenetic age (a shade under 44) and my DunedinPACE value at 0.71. A follow-up test, done six months later, shows my rate of ageing holding steady. The other big news was that the length of my telomeres had extended markedly.

Protective caps on the tips of chromosome DNA strands, telomeres have been likened to the aglets that protect shoelaces from fraying. Each time a cell divides, our telomeres shorten and they shorten faster under oxidative stress. Once they reach a critical length, the cell dies. Research in adults has shown that telomere length is a predictor of lifespan and is causally linked to age-related diseases. According to the latest test results, mine have actually extended from 7.01 to 7.24 kilobases, longer than 97.94 per cent of people my age. On this measurement, my predicted biological age is 30.90.

Before I celebrate too hard, though, the full reveal of how my baseline data has shifted over a period of 12 months will come when I do a final test, on the day of my 60th birthday.

Over the past year, Ive made some lifestyle tweaks in an attempt to shift the dial in the right direction more alcohol-free days, a bit more exercise (hampered by a knee and shoulder injury), a daily dose of the blackcurrant-based brain drink repa, a monthly visit to my osteopath Glyn Flutey, and a regime of SRW supplements, Cel1, Cel2 and Cel3, developed in collaboration with leading scientists around the world to support nine key cellular functions that decline with age.

One of the molecules in Cel1 is astragaloside, a compound found in a plant root that stimulates telomere repair. Ill never know for sure but it seems likely the supplements have contributed to my positive result. An observational trial by the company in New Zealand showed a biological age reduction of two and a half years in people who took the full suite of Cel supplements for six months. An independent 12-month trial SRW hopes will verify those findings is now underway in the US.

Apart from a regular yoga class, and a hypnotherapy session to help break a lifetime habit of grinding my teeth, I havent specifically targeted stress reduction yet as a way to work on lowering my biological age. I did a transcendental meditation course once, in my early 30s, and I know my brain needs some time to slow down, but fitting in two 20-minute sessions a day just never seemed realistic to me.

Rachel Grunwell, a former investigative journalist-turned-wellness coach, teaches mindfulness meditation through her company Inspired Health to a whole range of clients, from people like me to corporate directors and high-performance athletes. The mother of three boys and a former Herald columnist, she interviewed 30 global experts for her recent book Balance: Food, Health + Happiness and found plenty of science to support the idea that lowering stress levels can help slow down ageing.

We live on a planet thats speeding up; everything is getting faster and faster, she says. I feel anxious just thinking about the idea of having to fit 20 minutes of meditation into my life! But even taking a minute can be incredibly powerful to slow down your breathing, be in the moment and reset a stressed nervous system.

ONE-MINUTE MEDITATIONS

Chronic stress hammers the body physically, increasing your risk of everything from heart disease (particularly for women post-menopause) and high cholesterol to depression and cognitive problems. It can actually shrink your brain. Here are three mindful minute tools wellness coach Rachel Grunwell recommends to help de-stress your nervous system:

Box breathing meditation: Breathe in for four counts, pause for four counts, breathe out for four counts, pause for four counts. Repeat. This forces you to slow down your breathing and focusing on the count is a good distraction.

20-second hack: Practise belly breathing by imagining youre blowing up a balloon in your belly as you inhale. Then, as you breathe out, picture the balloon deflating. To check if youre doing it right, place one hand on your chest and the other on your stomach to see which one moves as you breathe.

Body scan meditation: You can do this sitting, lying down or with your legs up the wall. Taking deep belly breaths, scan yourself from the feet up, relaxing the different parts of your body on each exhalation. Especially good just before sleep.

10-second hack: Most of us carry tension in our shoulders. Grab a few seconds to take a deep breath, squeeze your shoulders up towards your ears as high as you can, hold for a beat or two, then release with a strong out-breath.

Senses meditation: When youre having a hot drink, at home or at a cafe, tune into all your senses to be present and aware in the moment. Savour the feeling of the warm cup in your hands, the patterns you see in the crema, the sounds you can hear around you, the aromas you can smell, the taste in your mouth.

10-minute hack: If youre in a virtual meeting where you need to listen but not participate, pop in your earbuds and go for a quick walk. You cant be entirely anxious when youre walking, says Grunwell. Part of your brain disengages. Or just be still and look for shapes in the clouds.

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Terminator’s Ultimate Weapon Was Only Unlocked by Alien DNA – Screen Rant

Posted: at 9:11 pm

Summary

Terminators are some of the most formidable and deadly Sci-Fi villains in the history of the genre, but they didnt reach their peak until they merged with another science fiction monster, Aliens Xenomorph. The hybridization of the two creatures unlocked the Terminators' ultimate weapon, one that it could never have wielded without Xenomorph DNA.

Despite the fact that these respective franchises originally had nothing to do with each other upon their films initial releases, their crossover comic series Aliens vs Predator vs The Terminator asserts that Alien and The Terminator have been a part of the same continuity all along. Apparently, Alien takes place in the future after Skynets attack on Planet Earth and the AIs subsequent defeat to the Human Resistance led by John Connor. It seems Skynets reign was pretty short-lived, though remnants of the evil artificial intelligence remained scattered across the galaxy. As humanity rebuilt from the ashes of Skynets assault on the planet and became the space-faring race of humans introduced in 1979s Alien, a rogue squadron of surviving Terminators is plotting the return of Skynet. By the time of this crossover - which takes place after Alien Resurrection - those rogue Terminators finally figured out how they were going to pull it off.

In Aliens vs Predator vs The Terminator by Mark Schultz and Mel Rubi, the remaining Terminators are able to successfully create Terminator/Xenomorph hybrids. These creatures have the biological weapons inherent in every Xenomorph, along with the ferocity and hive-mind-like coordination of the perfect organism, but thats not all. This hybridization also gave the Terminators an entirely new ability, one that isnt derived from either the Xenomorph or the Terminators entirely, but is rather a unique result of their merging: the Absorption Matrix. This ability allows the hybrids to literally absorb their physical surroundings, which both makes themselves more durable in any given situation with the added benefit of absolutely demolishing their surroundings, which is an aspect to the ability that can be weaponized in and of itself given the right circumstances (like inside a spaceship or within a highly volatile laboratory, for instance).

This ability manifested through the sheer malleability of Xenomorph DNA, and the Terminators ability to manipulate it to suit their needs. It is well established in Alien canon that Xenomorphs adapt gradually to their surroundings with each generation, as their hosts allow them to evolve through genetic imprint, which naturally makes them better suited for their environment. The Terminators know this, but since they cant impart pieces of themselves with every new generation of Xenomorph in the more natural way (if one considers Facehugger impregnation natural), they opted to speed up that process through experimentation.

These experiments conducted by the Terminators to create the best versions of themselves for the resurgence of Skynet results in perhaps the most ferocious Terminator in the history of the franchise, one with an ultimate attack it could never have had without the DNA of Aliens Xenomorph.

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Terminator's Ultimate Weapon Was Only Unlocked by Alien DNA - Screen Rant

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For the First Time, AI Brain Chips Allow Paralyzed Man to Move and … – Futurism

Posted: September 1, 2023 at 5:31 am

Image by Getty / Futurism

"It was a Sunday afternoon," Keith Thomas, a 45-year-old Long Island native, told us of his accident. "I dove into the wrong side of the pool, and I blacked out."

The next thing he knew, Thomas says, he was being airlifted to a nearby hospital; it was July 2020, just a few months into the pandemic, and he'd badly broken his neck at the C4 and C5 vertebrae of his spine. He's been paralyzed from the neck down since, unable to move or feel his limbs until a few months ago, that is, when a first-of-its-kind clinical trial brought both movement and feeling back to his arms and hands for the first time in three years.

Thomas, who lives with quadriplegia, was the first patient to receive what his doctors are calling a double neural bypass, a new bioelectrical therapy pioneered at Northwell Health's Feinstein Institutes for Medical Research. Led by Chad Bouton, a professor at Northwell's Institute of Bioelectronic Medicine, the experimental new procedure involves a combination of AI, brain-computer interface (BCI) implants, external computers, and non-invasive wearable tech.

Like a coronary bypass surgery creates a detour for your heart to pump blood around an obstacle, a neural bypassuses a combination of machine learning and electrical signaling to reroute an individual's neural signals, avoiding whatever barrier is preventing them from making it where they're supposed to go. A double neural bypass, then, reroutes the signal in just one but two places:in this case, the areas responsible for movement and touch.

The goal? To answer an elusive question: how do you restore the communication between the brain and the body, when the two can no longer speak?

"It's a very challenging problem," said Bouton, who's also the founder and CEO of a biotech firm called Neuvotion, over a video call. "You're looking at these complex electrical patterns in the brain, and you're trying to make sense out of the patterns and extract information from them. We want to know when someone's thinking about moving their hand, or moving their fingers, and we want to be able to then channel those thoughts into something useful."

Bouton and his team refer to this approach as "thought-driven therapy," in which chips embedded in the patient's brain use machine learning to interpret the complex language of neurons. Does it sound like sci-fi? Absolutely. But so far, it's showing unmistakable promise and the implications for the millions worldwide who suffer from paralysis or movement impairment could be significant.

"It's frustrating when someone looks at their limb, and they can't make the movement they want to make," Bouton said. "They're trying, and the brain knows they're trying, but things aren't happening. It's super frustrating, and it can be depressing."

The professor and his team performed the world's first single neural bypass surgery back in 2016, successfully restoring movement in the arms of a patient who had broken his neck on a family vacation six years prior. But while that procedure was able to reestablish the ability to move when hooked up to a computer, that is it didn't bring back the patient's sense of feeling.

Now, seven years later, the double neural bypass has been designed to do both: bring back movement and sensation.

In Thomas' case, he first had to spend months staring at simulated arm and hand movements on a computer screen, urging his brain unsuccessfully, at the time to mimic the motions. The doctors and engineers, meanwhile, took detailed MRIs of his brain, mapping the areas responsible for arm movement and hand touch. (Like searching for a needle in an extremely delicate, blood vessel-laden haystack, Bouton told us.)

Armed with this data, the doctors then hatched a plan to implant a total of five BCI chips: two at the area of the brain that presides over movement, and three at the region responsible for touch and feeling in the fingers. The chips pass decoded bioelectrical messages to the computer,which then sends electric signals to a series of electrode-laden patches placed across Thomas' spine and forearms. Finally, a handful of infinitesimal sensors placed on Thomas' fingertips and palms send touch and pressure data back up to the sensory region of Thomas' brain.

"Every time he thinks about moving and feeling, we actually send another signal to the spinal cord, and that supercharges the spinal cord," said Bouton. "It tries to strengthen connections."

Installing the chips was no small feat. Thomas underwent a 15-hour open brain surgery back in March, and as if that wasn't enough on its own, the Long Islander was awakefor large portions of the procedure, verbally relaying the sensations he was feeling back to Bouton and his surgeons, a team led by Northwell neurosurgeons Ashesh Mehta and Netanel Ben-Shalom.

But Thomas "didn't really have any reservations" about the surgery, he recalled, before conceding: "until the night before."

Fortunately, the procedure was a resounding success. The BCI install went off without a hitch, and for the first time since his accident, Thomas was able to hold and feel his sister's hand.

"It was incredible," Bouton recalled. "It still makes me tear up."

In the four months since the procedure, Thomas has regained full strength in both arms, even experiencing a 110 percent recovery in his right arm. But most excitingly, Thomas has started to experience natural recovery in his forearm and wrist meaning that the therapy might have kickstarted his nervous system's innate healing processes.

"Only several months into the study, he's making huge gains," Bouton said, "doubling his arm strength, and starting to feel new sensations in his forearm and even wrist even after he goes home outside the lab, even when we turn [the computer] off."

When we reached out to experts in the field, enthusiasm for the procedure's success and AI's role in it was palpable.

The surgery is a "novel and exciting advance in the field of both BCI and spinal cord neuroprosthetic interfaces," Dr. Wilson Zachary Ray, Executive Vice-Chair of the Department of Neurosurgery and chief of spine surgery at the Washington School of Medicine in St. Louis, who wasn't involved in the study, said over email. "I suspect this sort of AI and ML innovation will see a massive growth in clinical applications over the next 3 to 5 years."

"At some point in the not too distant future," Ray added, "implantable 'smart technology' will be integrated into the fabric of our daily life, similar to how all view our smartphones today."

But as remarkable as these results are, they're not without caveats. Although Thomas has experienced new sensations outside the lab, the computer needs to be turned on in order for him to be able to move. And as Bouton told us in our interview, the contraption itself isn't exactly minimalist.

"It's kind of like the early heart and lung machine," the professor told us of the contraption. "We've got some parts that are in the body, some parts that are on the laboratory table, and some wearables."

But over time, he says, the goal is to condense the device's size, ideally to the point that it's portable. His company, Neuvotion, is working on a number of non-invasive treatments and devices seeking to restore autonomy to those suffering movement impairment and paralysis, among other applications.

"In the more challenging cases, like Keith's," he added, "combining brain-interface technology with non-invasive devices is powerful."

The recovery also requires a lot of effort for patients hours-long therapy sessions, visits with specialists as they relearn how to move and strengthen those movements, one day at a time.

"You have to be really patient, and really dedicated, to want to do this," said Thomas. "It's a lot of work." Recounting his many weekly therapy sessions and visits to specialists, he added: "It's pretty much a full-time job, being quadriplegic."

But Thomas doesn't mind. The "stars aligned" for him to meet Bouton, he says, and seeing the tangible results of his effort has been extraordinary. If his role in this research helps others down the line, according to Thomas, it's all worth it.

"All of the effort that I'm putting in is paying off," he told us. "I realize it's not going to happen overnight, but the little things reaching up to my chin, being able to touch my other hand, rub my cheek when I have to, call people." He quieted for a second. "It's the little things."

More on paralysis technology: Paralyzed People Successfully Test Brain-controlled Electric Wheelchairs

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OpenAI Rages at Report That Google’s New AI Crushes GPT-4 – Futurism

Posted: at 5:31 am

AI bro fight! AI bro fight! Clash of the TAItans

Buttons? Pressed.

Over the weekend, researchers Dylan Patel and Daniel Nishball, who together write a semiconductor blog called SemiAnalysis, published a controversial post declaring that Google's secretive upcoming AI model, dubbed Gemini, is about to blow OpenAI's GPT-4 out of the water. According to the blog brusquely titled "Google Gemini Eats The World Gemini Smashes GPT-4 By 5X, The GPU-Poors" Google's expansive infrastructure of advanced GPUs gives the Silicon Valley stalwart and its next-gen model a leg up over the latest iteration of OpenAI's GPT-4.

Which, as conversations across sites like X-formerly-Twitter and Hacker News made clear, is a contentious take. Does more computing power reallyequal a better AI model?

It's a fascinating question, and some online debates got heated. But no one, it seems, was more perturbed by the statements in the blog than OpenAI CEO Sam Altman, who took to X-formerly-Twitter on Monday to scoff at the researchers' analysis.

"Incredible Google got that SemiAnalysis guy to publish their internal marketing/recruiting chart," Altman wrote in the post, referring to an infrastructure chart included in the blog. His signoff to the message: "lol."

Patel, one of the blog authors, didn't take Altman's critiques lying down, and on Tuesday hit back with an X post of his own.

"Sundar to the GPU-poors," the researcher captioned the post, which included an NSFW meme of Google-owning Alphabet CEO Sundar Pichai appearing to force-feed milk to Altman. "The data is from a supplier of Google," Patel added, "and we made the chart."

It's not surprising that Altman isn't a fan of the SemiAnalysis post, given that it pretty much just says that Google products will absolutely wallop OpenAI's by the end of the year. And to his credit, as a number of netizens pointed out, the Semiconductors Rule All argument might lack some nuance.

"Computational power alone is not the only resource. It is also the training process itself... and, obviously, data and its quality," one Hacker News user wrote, as caught by Insider. "I will be convinced only after Google demonstrates that Gemini is better than GPT4 (in some, or all, tasks)."

A fair point. Still, it'salsotrue that, thoughOpenAI's ChatGPT release kickstarted the publicview of the AI race, Google which has used its immensely deep pockets to pioneer the world of AI R&D for some time now likely has some powerful stuff up its sleeves. Regardless, at the end of the day, it's always fun to witness Silicon Valley's most powerful bristle at any affront to their perceived superiority.

More on AI: AI's Dirty Secret: Poor People in the Developing World Are Doing Most of the Work

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Paolina Russo, the Brand Morphing Ancient Craft Into Futuristic … – AnOther Magazine

Posted: at 5:31 am

August 28, 2023

Who is it? After graduating from Central Saint Martins MA in Fashion (Knitwear) program, Paolina Russo launched her eponymous label alone, until a cosmic moment brought her together with fellow CSM graduate Lucile Guilmard. We shared a studio together and then one morning we just said Look, can we do this together? recalls Russo. And thats when the brand really flourished when there were two minds behind it, a merging of two creative communities.

Despite coming from different backgrounds Russo grew up in Canada; Guilmard in France the two share a common language in crafts, as both an artistic form and a reactive, solution-oriented process. Both were introduced to traditional clothes-making techniques at a young age via family members, which instilled in each of them an organic appreciation for the hands-on knowledge transfer involved in fashion design. Together, they share a reverence for the pure magic of these ancient crafts yet cradle their potential to innovate solutions for the future.

Knitwear, the brands specialty, is, for example, something that has existed for thousands of years but theres so much newness in it and excitement about where you can take it into the future. Even if something seems theoretically impossible, by working with other knitwear developers we are always able to find some sort of practical solution, says Russo of their collaborative approach. It really is a sort of alchemy.

This ethos of communal effort, of intergenerational savoir-faire is the spirited soul of Paolina Russo. The designers always start the development of a new collection by spending time on the ground in the factories they work with. Each step of this process is honestly documented on social media, to make visible, and celebrate, the many hands involved in the making of their garments. Its very important for us to meet the people because everything we do is really craft-based and craft is something that comes from communities. It exists today because its been passed down from generation to generation, explains Guilmard, We want to make sure that this remains a human story, with human hands.

Why do I want it? Russo and Guilmards deft talent for construction and technique, and their singular vision of colour and motif, have allowed them to so magically transform a heritage craft into futuristic folklore. Their signature sculptural knitwear is both fresh and familiar, as the duo so harmoniously balance technical innovation with folkish motifs and playful palettes. But even if there is a certain novelty in the silhouettes, the designers always ground their garments in a sense of longevity: each piece is made from high-quality, natural fibres using innovative techniques to ensure durability.

For their Spring/Summer 2024 collection, Monolith, presented at Copenhagen Fashion Week as part of the Zalando Visionary Award, the designers drew parallels between prehistoric cave markings and the chalked pavement scribbles of their childhoods to emphasis the intelligence of human ancestral wisdom, so often ignored in our Age of Information and Technology. Perfectly dirtied jeans laser-cut with runic symbols, the brands first foray into denim, were styled with wrapped, convex knits; slouched jersey tops were given form with talismanic wooden fastenings. Any tension between past and future was overridden by a brightly-hued optimism for the ability of traditional craftsmanship to endure within future technological landscapes.

Russo and Gailmards approach to sustainability is just as rigorous and socially conscious as their design process. Every step, from the origins of the fibres to the post-consumer journey, is considered. With each collection, they choose to focus on a single fibre and for S/S24 it was cotton. All of our knitwear, denim, jersey, are 100 per cent cotton, explains Russo. Its really important for us as we develop things to consider the post-consumer journey. To know that if the pieces end up in landfill, they can biodegrade. The designers personally visit the sources of all material used and make this information transparent via social media.

As Paolina Russo continues to grow, the designers remain passionately committed to ongoing education regarding technique and material and then sharing all they learn with their community through workshops and social media. Design is about finding solutions to problems and thats why we love fashion. Once you open one door, the conversation is widened. And thats what makes this craft so fascinating and beautiful.

Where can I find it? Paolina Russo is available at Dover Street Market London (both in-store and online), SSENSE, Addicted, ALTER, and SVRN.

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Are We Ready For This Site’s Endless Feed of AI-Generated Porn? – Futurism

Posted: at 5:30 am

In one bizarreand deeply NSFW corner of the internet, a website called PornPen.aiis churning out an endless feed of graphic, chaotic, and widely varied pornographic imagery all of which, the site makes very clear, was generated using AI.

With a fusillade of new images cropping up in the live feed constantly, the effect can be overwhelming. Some are impressively photorealistic, while others are intentionally cartoonish. Many carry at least one telltale sign of AI generation,from malformed hands or an extra appendage to abnormalities in eyes or ears (the AI is also weirdly bad at depicting penises, for some reason.)There's substantial diversity in body type, age, race, and gender, though you have to click an option to see men in the feed, suggesting a heterosexual male preoccupation to the project.

Staring at the PornPen feed, it's difficult to not have mixed feelings. On the one hand, erotic art and sex work are as natural to the human experience as anything else; there's a 37,000-year-old depiction of a vulva etched into the ceiling of France's Chauvet cave, after all.

But as human as porn has always been, AI is distinctly inhuman. An algorithm is essentially gobbling up human-made imagery, remixing it, and regurgitating it to suit the desires of horny users. And between the rise of thirst-trapping AI-generated influencers, the deep attachments that people are forming to AI companion programs like Replika, and the onset of chatbot-enabled AI sexting, it seems that AI's role in the vast landscape of porn, sex, and relationships is only just beginning to take form. While this is something we've been imagining through science fiction for some time now think "Her," "Ex Machina," "Blade Runner," and so on we still have absolutely no idea how this burgeoning sexual arena might play out in the real world.

So in a sense, sure, maybe PornPen is just an inevitable new milepost in the thousands-year-old history of smut. But it also feels like a sign of things to come. If so, maybe it's worth asking how this kind of endlessly customizable sexual solipsism might impact real-world relationships, not to mention the economics of the pre-AI porn industry.

AI advocates often see the tech as something that will either save the world or destroy it. The creator of PornPen, who goes by the moniker Dreampen, falls optimistically into the former camp:as he tells it, AI will be a tool that produces erotic content in a safe way, unlocking creativity and even empowering adult performers.

"When Stable Diffusion first came out, I saw that many people were trying to make NSFW content," he told us via email. "A lot of AI generator sites blocked this content, and people were also making illegal content such as deepfakes. I wanted to fulfill the AI porn desires in a safe way."

There are design choices to try to keep PornPen from going off the rails. The site, which is built on the open-source Stable Diffusion image generator, only allows users to access preset tags for generation purposes. So users can builda prompt, but they can't actually write their own. That prevents bad actors from writing in celebrity names, Dreampen says, or requesting depictions of violent or illegal acts or "other harmful prompts."

"I thought this was a clever way to preserve safety," said the developer, "while giving people some creative flexibility."

The site seems to be connecting with an audience. If its constantly-populating feed wasn't evidence enough, PornPen's Discord community boasts about 25,000 users and its Subreddit has another 32,500 members.

Perhaps most notable is PornPen's success on Patreon. Though a slower, more basic version of the site is available for free, coughing up $15 a month to upgrade to "Pro Mode" grants the most dedicated users access to a faster, higher-quality, and more expansive more tags to choose from, advanced editing options, unlimited generation rights, and more of the like iteration of the site. The project's Patreon currently has nearly 7,000 paying members,suggesting that it's pulling in yearly revenue of more than a million dollars.

That's a lot of cash and a clear sign, it seems, that AI-generated porn can be lucrative.

"People want to look at porn and they want to customize it to their tastes," said the creator, adding that "many users have stated that they enjoy PornPen because they know people aren't exploited."

Exploitation is something that Dreampen pays a lot of lip service to, telling us that his ultimate goal with the site is to fully "end human exploitation" in the adult industry. That's an interesting way to look at it: porn has historically been rife with abuse, and if humans were to be fullyremoved from it, it would technically eliminate any exploitation going on.

But the nature of AI makes the specifics of exploitation murky. PornPen was trained using the LAION-5B dataset, a large-scale AI training dataset scraped from the web by the nonprofit Common Crawl. That means the nude figures on PornPen's endless feed are, in a sense, mashed-up composites of people whose images appeared in it. Did they give consent,in any reasonable way,to be included in something like this?

There's also the fact that not all porn is exploitative. Much of it is done under the full consent and control of performers, particularly in an era where platforms like OnlyFans, though still flawed, have granted sex workers more agency than ever before.What will sites like PornPen mean to them?

Again, Dreampen has a cheery outlook.

"I've actually had OnlyFans creators reach out to me asking to use my platform," said the developer. "Creators are interested in training custom models on their own data, so they can use AI to make pictures of themselves. One creator, who was getting older and thinking of retiring, realized that they could 'immortalize' their younger body into AI, and keep their business stream going that would have otherwise ended."

It's an interesting point. And Dreampen also argues that AI could give performers new ways to streamline their businesses.

"I see [the site] as a tool which can improve the workflow for sex workers," he said, noting that some OnlyFans creators have been known to outsource chats with users to outside ghostwriters. "Users are not even chatting with the actual creator. In some ways, their persona is already a virtual avatar that is managed by the original person."

"In that world," he added, "why can't the images/videos themselves also be 'outsourced' to AI?"

Like the rest of the AI-sex landscape, PornPen sits squarely in a gray area. In some respects, it's tempting to peruse ersatz smut in which no performers were underpaid or coerced. But if it becomes the norm, it could spell disaster for all the performers who are creating adult content on their own terms. It's an ominous new unknown. It splits our already-flimsy, post-social-media conceptions of reality and fantasy apart, recombining the pieces into something entirely brand new.

How it'll all ultimately unfold, no one knows. But Dreampen, for his part, certainly has some ideas.

"I think sites like Pornhub will have to adapt or acquire companies, otherwise they will get beaten by new sites with new technology," he said, adding that "AI porn will create a new category of adult performer."

"Essentially, people can create an AI avatar that they manage, and people will pay to interact with them," he continued. "Online sex work won't rely on people using their own body, and the industry becomes more accessible."

More on AI-generated fantasies: Guy Who Uses AI to Post as a Voluptuous Influencer: "I Usually Just Call Myself Her Manager"

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Lawson addresses labor shortage with futuristic avatars | The Asahi … –

Posted: at 5:30 am

To address a growing labor shortage, major convenience store chain Lawson Inc. is introducing a technology that enables remote workers to serve customers using animated avatars.

Sitting in front of computer screens at their homes or offices, workers act as Lawson Avatar Operators (LAOs) to serve customers.

LAOs talk to webcams and their voices and gestures will be reflected on animated characters on screens atLawsonoutlets.

Currently, LAOs are operating at four of the chains stores in Tokyo, Osaka and elsewhere.

Lawson said that on-site workers at these stores can focus on physical tasks such as cooking, cleaning and stocking shelves while LAOs help customers, for example, use the self-checkout machine.

The chain will start a trial to see if a single LAO can deal with three or four outlets during the day as well as short-staffed late night and early morning hours. The pilot program will start as early as August.

Until now, at least two workers would do night shifts together at Lawson outlets, mainly for security reasons. During the trial, one will be replaced by an LAO.

This might put stores at greater security risk, but the chain operator says robberies are on the decline thanks to the introduction of self-checkout machines, which, by design, cannot be unlocked by on-site workers.

Customers can continue to pick up event tickets bought online and drop off parcels at Lawson outlets. Such services will remain the task of on-site workers.

Labor shortages will become more serious in the future, particularly for night shifts, said Lawson President Sadanobu Takemasu. A single LAO manages multiple outlets from home, which means more productivity with lower cost.

Together with self-checkout machines, the avatar technology is expected to help run outlets with fewer workers.

Lawson also hopes the new technology will help recruit more remote workers, including people rearing children or caring for family members at home.

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Paper Straws Are Actually Worse Than Plastic Ones, Scientists Say – Futurism

Posted: at 5:30 am

Image by Stephen Zeigler via Getty Images

When you use a paper straw for drinks, you might think you're being a conscientious citizen of Planet Earth. If so, bad news: a team of scientists say paper straws have more harmful forever chemicals than plastic ones, and at higher concentrations. Well, at least we tried.

Scientists in Belgium discovered that per- and polyfluoroalkyl substances, or the PFAS known as "forever chemicals," were "more frequently detected in plant-based materials, such as paper and bamboo" versus plastic ones, as detailed in a new paper in the science journal Food Additives & Contaminants.

"Straws made from plant-based materials, such as paper and bamboo, are often advertised as being more sustainable and eco-friendly than those made from plastic," said Thimo Groffen, an environmental scientist at the University of Antwerp who worked on the research, in a blurb about the findings. "However, the presence of PFAS in these straws means that's not necessarily true."

The scientists looked at 39 brands of drinking straws made from five different materials: plastic, stainless steel, bamboo, glass and paper. Within this cohort, scientists detected PFAS in 27 of them.

Paper straws were most likely to test positive for PFAS, with 90 percent of the paper straws having the forever chemicals versus 75 percent in the plastic ones. The paper straws had far higher concentrations of forever chemicals versus plastic.

Almost all the other straws made from different materials also had PFAS, except for stainless steel.

The scientists said manufacturers use PFAS in plant-based straws in order to make them more "water-repellent," but they could also be introduced through contaminated raw materials.

The news shows that it's difficult for consumers to make virtuous or even healthy choices when many of the options on the market are a "pick your poison." It makes any eco-conscious person want to throw their hands up in despair.

The Belgian study corroborates an earlier study from 2021 published in Chemosphere that detected the forever chemicals in paper straws but found plastic straws "had no measurable PFAS."

What's unfortunate about PFAS is that some are water soluble. Yikes. So what's a person to do? Stick with stainless steel? But those are a pain to clean.

Currently, the Environmental Protection Agency aims to get rid of forever chemicals via a whole host of proposed rules and investment dollars. Perhaps in the future, these chemicals will be a thing of the past but meanwhile, every sip is a slow drip of poison.

More on straws: The Anti-Straw Movement Was Dumb, Annoying, and Actually Worked?

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AI’s Dirty Secret: Poor People in the Developing World Are Doing … – Futurism

Posted: at 5:30 am

Dirty Secret

Artificial intelligence has a dirty secret that we're not talking nearly enough about.

It's that Silicon Valley AI firms are relying on cheap labor overseas, and tasking them with the grueling labor required to make them actually work and more often than not, their wages and working conditions are poor, the Washington Post reports.

Millions of people in the Philippines are being tasked with labeling images, allowing AI algorithms to make sense of the world. Sometimes they're asked to make sense of chunks of text to make sure AI chatbots like OpenAI's ChatGPT don't end up spurting out nonsense.

But many of these workers are being exploited and severely underpaid a worrying and often overlooked aspect of the ongoing AI arms race,as debates have focused instead on grabbier issues of potential bias or the possibility of AI going rogue.

According to the report, San Francisco-based startup Scale AI employs at least 10,000 people in the Philippines on a platform called Remotasks. However, according to data and interviews obtained by the WP, the company has often failed to pay them on time (a Scale AI spokesperson told WaPo that "delays or interruptions to payments are exceedingly rare.")

A number of Remotasks freelancers told the newspaper that they were stiffed on payments or never received the money they were initially promised. One 26-year-old worker spent three days on a project, hoping to get $50. He only got $12.

Filipino AI ethicist Dominic Ligot called these new workplaces, which house workers labeling footage or text for AI companies like Scale AI, "digital sweatshops."

Workers also don't have any effective avenues to complain and can simply be "deactivated" if they were to raise their voices.

And it's not just the Philippines. Scale AI is also employing freelancers or "taskers" in Venezuela and India, triggering a "race to the bottom," as the owner of an outsourcing firm told the WP.

In short, while AI has triggered a billion-dollar arms race in the US, those who are actually doing the brunt of the work are often going unnoticed, underpaid, or ignored altogether a wrinkle in the ongoing AI ethics debate that should give anybody pause.

More on AI ethics: The Pope Just Released a Guide to Artificial Intelligence

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One-Off BMW K 1100 RS Cafe Racer Matches Futuristic Looks With … – autoevolution

Posted: at 5:30 am

The K-series bikes from BMW Motorrad are by no means ideal for a custom build that leans toward the retro side. However, they are perfectly suited to projects which aim for futuristic looks, and there are plenty of great examples out there. Not many of them are as extensively modified and well put together as the one were about to look at, though.

Photo: Paul van Mondfrans Linden

He tried his hand at modifying the K 1100 RS back in 2022, and the result is quite simply dazzling! Not only did Powerbricks mastermind give it a seductive cafe racer presence, but he also came up with a ton of performance upgrades to match the sharp looks. The engine, suspension, and brakes have all been dialed up to eleven, thus bringing the old '94 MY sport-tourer into the 21st century.

Starting with the rear-end modifications, Tim extended the motorcycles swingarm by 15 millimeters (0.6 inches), which was easier said than done given its Paralever design. The original shock absorber was replaced with a premium G-Racing unit from YSS, featuring full adjustability and a piggyback reservoir. Its upper end connects to a bespoke subframe built from scratch, and theres a gorgeous solo seat placed up top.

The saddle flaunts a mixture of standard black leather and suede, all finished off with stylish honeycomb pattern stitching. A pointy 3D-printed tail section is mounted right behind the seat, and its rearmost tip houses a compact LED taillight. Tim attached a handmade electronics tray to the subframes underside, filling it with a NOCO lithium battery and Motogadgets mo.Unit Blue control module, among other goodies.

Photo: Paul van Mondfrans Linden

Moreover, a custom nose fairing found its way onto the Beemers front end, encircling a Thunderbolt LED headlight from Kosos inventory. The cockpit area is an absolute charm, too, bearing clip-on handlebars and a digital Motoscope Mini dial supplied by Motogadget. Tim recessed the latter into the top clamp for a clean look, then he garnished the clip-ons with an array of top-shelf components.

These include Brembo control levers, a Domino throttle, and new switches, as well as Motogadget bar-end turn signals and Biltwell grips. We still find the factory K 1100 RS fuel tank center-stage, but its been outfitted with a fresh aluminum filler cap and CNC-milled BMW roundels. That just about does it for the machines upper equipment, so lets have a gander at the unsprung side of things.

Photo: Paul van Mondfrans Linden

Now, Tim didnt apply all these upgrades just for the sake of it, but to prepare the K 1100 RS cafe racer for a considerable dose of additional power. The bikes 1,092cc inline-four engine made a respectable 100 hp in its stock configuration, though it could certainly do better on Powerbricks watch. Sir Somers ported the air intakes to let the transverse four-cylinder breathe more freely, and he added a quartet of DNA pod filters for the same purpose.

His grocery list also contained Bosch EV14 fuel injectors and NGK ignition hardware, as well as an aluminum RC Racing radiator to keep things nice and cool. Samco silicon hoses transport the coolant from the engine to the radiator and back, but its the other piece of plumbing that really grabbed our attention from the start. Of course, were talking about the striking pie-cut exhaust system which Tim pieced together in-house.

Built out of stainless-steel, the pipework snakes its way back in a four-into-one configuration, before ending in a stubby aftermarket silencer. Last but not least, the color scheme applied by Powerbrick is both sporty and elegant, employing a dark grey base topped with large white stripes on the bodywork. However, the red highlights are what really makes this thing pop, appearing on various items such as the forks, shock spring, brake lines, and coolant hoses.

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