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Category Archives: Transhuman News

KidsHealth for Parents – Gene Therapy and Children

Posted: January 5, 2014 at 5:42 am

Gene therapy carries the promise of cures for many diseases and for types of medical treatment most of us would not have thought possible. With its potential to eliminate and prevent hereditary diseases such as cystic fibrosis and hemophilia and its use as a possible cure for heart disease, AIDS, and cancer, gene therapy is a potential medical miracle-worker.

But what about gene therapy for children? There's a fair amount of risk involved in trials of this kind of therapy, and to date, only kids who are seriously ill or have illnesses incurable by conventional means have been involved in clinical trials using gene therapy.

For those with serious illnesses that aren't responsive to conventional therapies, however, gene therapy may soon offer hope that didn't exist just a short time ago.

Our genes are part of what makes us unique. Inherited from our parents, they go far in determining our physical traits like the color of our eyes and the color and texture of our hair. They also determine things like whether babies will be male or female, the amount of oxygen blood can carry, and IQ.

Genes are composed of strands of a molecule called DNA and are located in single file within the chromosomes. The genetic message is encoded by the building blocks of the DNA, which are called nucleotides. Approximately 3 billion pairs of nucleotides are in the chromosomes of a human cell, and each person's genetic makeup has a unique sequence of nucleotides. This is mainly what makes us different from one another.

Scientists believe that every human has about 25,000 genes per cell. A mutation, or change, in any one of these genes can result in a disease, physical disability, or shortened life span. These mutations can be passed from one generation to another, inherited just like a mother's red hair or a father's brown eyes. Mutations also can occur spontaneously in some cases, without having been passed on by a parent. With gene therapy, the treatment or elimination of inherited diseases or physical conditions due to these mutations could become a reality.

Gene therapy involves the manipulation of genes to fight or prevent diseases. Put simply, it introduces a "good" gene into a person who has a disease caused by a "bad" gene.

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KidsHealth for Parents - Gene Therapy and Children

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Gene Therapy – Nature

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At the forefront of medicine, Gene Therapy brings you the latest research into genetic and cell-based technologies to treat disease. It also publishes Progress & Prospects reviews and News and Commentary articles, which highlight the cutting edge of the field.

Volume 21, No 1 January 2014 ISSN: 0969-7128 EISSN: 1476-5462

2012 Impact Factor 4.321* 70/290 Biochemistry & Molecular Biology 22/159 Biotechnology & Applied Microbiology 33/161 Genetics & Heredity 25/121 Medicine, Research & Experimental

Editors: J Glorioso, USA N Lemoine, UK

*2012 Journal Citation Reports Science Edition (Thomson Reuters, 2013)

Download the presentation from our How to Get Published Session. (281 kB)

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Gene Therapy now offers authors the option to publish their articles with immediate open access upon publication. Open access articles will also be deposited on PubMed Central at the time of publication and will be freely available immediately. Find out more from our FAQs page.

Reviews by top researchers in the field. See the recent Progress and Prospects articles.

Essential topics explored in depth in Gene Therapy Special Issues.

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Gene Therapy - Nature

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Obamacare is ‘A Conspiracy Of Stupidity’, Ron Paul – Video

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Ron Paul Dismantles Corporate Boondoggle Known as Obamacare The Alex Jones.

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Cancellations Outpace Enrollments As Obamacare Makes Its Debut – RPT – Ron Paul On Cavuto – Video

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The Word That Best Defines Libertarianism Is Non Intervention Ron Paul1].3gp – Video

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WATCH Krauthammer’s Take: Other than Obamacare, Biggest 2013 Story is Rising Libertarianism – Video

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Rand Paul is totally, shamefully wrong about the long-term unemployed

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Right-wing libertarian that he is, Rand Paul isnt much for using the federal government to make the world a slightly less terrible place. It was hardly a surprise, then, to find out the Kentucky senator opposed extending emergency unemployment compensation, preferring instead to let it expire for some 1.3 million in late December, with millions more to come after that. EUC is a federal government program, after all; and worse still, its one whose primary beneficiaries are the unemployed, a population with little political influence or social standing. Youd expect, in other words, Rand Paul to leave these people shuddering in the winter cold. Its what his rigid vision of libertarianism requires.

What was less predictable, however, was Pauls stated justification for opposing EUC. Rather than talk about makers and takers and the economys winners and losers, Paul attempted to repackage his laissez faire absolutism as a kind of tough love empathy. He pointed to a study that, he claimed, showed those on EUC had a harder time reentering the workforce (an interpretation one of the studys authors subsequently differed with). He talked about how those advocating for an EUC extension were doing a disservice to Americas long-term unemployed workers. He made kicking millions to the curb sound like nothing less than an act of benevolence, bordering on charity. Whether it was a feat of self-delusion or chutzpah, only Paul can really say. (My guess is somewhere in-between.)

But as is so often the case with right-wing libertarianism, Pauls flimsy moral reasoning simply disintegrates once it comes into contact with the facts on the ground. Implicit in Pauls formulation is the idea that there are jobs to be had, if only the long-term unemployed would stop relying on government checks and go and have them. Considering that the total number of long-term unemployed set to be sent adrift by the expiration of EUC is somewhere in the vicinity of 5 million, its quite likely that, in some instances, this is true. But for the vast, vast majority of those on EUC, the reality is that there simply are not enough jobs to go around. A Bureau of Labor Statistics study found the ratio of job seekers to job openings to be nearly 3-to-1, and thats the national figure in many regions, the chances of finding employment are considerably worse.

Whats more, Pauls understanding of the long-term unemployed also betrays a shameful ignorance as to what life on EUC is actually like. People on EUC arent collecting their former paycheck while sitting around and waiting for work to come to them. Theyre receiving a mere fraction of their former salary and are under constant pressure to prove that they are indeed searching for new employment. As Kim Merryman, a former water quality technician for an Indian reservation who was laid off in April, told me, Its not like [EUC] allows me to live this comfortable, cushy life. In 2012, the average weekly compensation for those on EUC was $300.

What EUC does do for Merryman and millions like her is allow her to have a roof over my head, have gas in my car, get down to the employment agency, [and] to get my rsums out. Rather than keep Merryman out of the workforce, in other words, EUC keeps her in it by helping her to continue to search for a job. Thats why economists believe ending EUC will lead to many of the unemployed simply giving up on finding a new job and dropping out of the workforce entirely. While this would technically reduce the unemployment rate, it would do little to actually improve the labor market or the economy on the whole. In fact, according to the nonpartisan Congressional Budget Office, because recipients of EUC tend to, out of necessity, spend the money right away, the expiration of the program could deprive the economy of as many as 200,000 jobs and 0.2 percent of GDP.

For these both moral and technocratic reasons, extending EUC is the mainstream position. A recent poll found that 55 percent of Americans support an extension, while only 34 percent oppose one. The Rand Paul school of thought, that those on EUC are layabouts turning down work in order to bask in the glow of their government-provided largess, is, thankfully, an outlier. And theres concrete political action taking place in Washington, too. With the White Houses backing, Democrats like Rhode Island Sen. Jack Reed are already trying to pass a three-month extension of EUC that will keep the 1.3 million cut off on Dec. 28 afloat while Congress hashes out a longer-term agreement. Nothings ever certain with Republicans in Congress, of course, but its in the GOPs self-interest to move the issue to the political sidelines, so theres reason for optimism that such a deal will ultimately pass.

All the same, that 1.3 million Americans have been forced to greet the new year with little to no idea how theyll next make ends meet is still a national disgrace. That so many Americans have been left to suffer through the hell of long-term unemploymentis itself a national disgrace. And even if this round of economic Darwinism proves to be short-lived, the reality ofa joblessrecovery meanstheres little doubt that millions more will soon find themselves in the impossible situation now confronting Merryman and so many like her. If thats the case, lets hope the long-term unemployed continue to have better friends in high places than the junior senator from Kentucky.

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