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Category Archives: Transhuman News
DNA evidence yields arrest in 2012 Rowland Heights rape case
Posted: January 13, 2014 at 3:47 pm
January 13, 2014, 7:02 a.m.
Authorities say they were able to use DNA evidence to track down a man who they say brutally beat and raped a 29-year-old woman in her apartment in 2012.
The woman, who has not been identified, woke up at 6 a.m. Oct. 27 in her Rowland Heightsapartment as Pablo Reyes Bautista, 26, attacked her, according to the Los Angeles County Sheriff's Department.
The break in the case came when DNA recently entered by the suspect resulted in a match from a national database.
Bautista was arrested "after an extensive manhunt" in Atwater Village, the department said. He previously lived in Rowland Heights, where the alleged attack occurred in the 1500 block of Jellick Avenue.
Bautista was charged with rape by force, aggravated mayhem and burglary, authorities said.
He is scheduled to be arraigned Tuesday.
Authorities are hoping that any other possible victims of Bautista will step forward and call the special victims bureau at (877) 710-5273.
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DNA testing confirms grey wolf shot in Wayne County
Posted: at 3:47 pm
UPDATE Ex-inmate, 2 others to be honored for saving life of 2-year-old Ex-inmate, 2 others to be honored for saving life of 2-year-old
Updated: Monday, January 13 2014 2:16 PM EST2014-01-13 19:16:48 GMT
A 2-year-old Pinal County girl is recovering after falling through a damaged septic tank lid and nearly drowning. Pinal County Sheriff's spokesman Tim Gaffney said the girl was walking with her mother
Henry Ricketts dove in head first to try to save a 2-year-old girl who fell into a septic tank in Maricopa. Others came to her rescue, too.
Updated: Monday, January 13 2014 9:44 AM EST2014-01-13 14:44:27 GMT
The question on many residents minds in Golconda is, when will the water come back on? Since Monday, Jan. 6 the town has been without enough water pressure in their water system to keep the town running.
The question on many residents minds in Golconda is, when will the water come back on? Since Monday, Jan. 6 the town has been without enough water pressure in their water system to keep the town running.
Updated: Monday, January 13 2014 2:24 AM EST2014-01-13 07:24:56 GMT
The plane, which was supposed to land at Branson Airport, landed at a nearby airport with a significantly shorter runway.
The plane, which was supposed to land at Branson Airport, landed at a nearby airport with a significantly shorter runway.
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DNA testing confirms grey wolf shot in Wayne County
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‘Lost’ remains of queen found
Posted: at 3:47 pm
The remains of a woman kept in an Indian church likely belong to an ancient queen executed about 400 years ago, a new DNA analysis suggests.
The DNA analysis suggests the remains are those of Queen Ketevan, an ancient Georgian queen who was executed for refusing to become a member of a powerful Persian ruler's harem. The findings are detailed in the January issue of the journal Mitochondrion.
Tumultuous lifeKetevan was the Queen of Kakheti, a kingdom in Georgia, in the 1600s. After her husband the king was killed, the Persian Ruler, Shah Abbas I, besieged the kingdom.
"Shah Abbas I led an army to conquer the Georgian kingdom and took Queen Ketevan as prisoner," said study co-author Niraj Rai, a researcher at the Center for Cellular and Molecular Biology in Hyderabad, India.
- Niraj Rai, a researcher at the Center for Cellular and Molecular Biology in Hyderabad, India
Queen Ketevan languished in Shiraz, Iran, for about a decade. But in 1624, Shah Abbas asked the queen to convert to Islam from Christianity and join his harem. She refused, and he had her tortured, then executed on Sept. 22, 1624. Ketevan the Martyr was canonized as a saint by the Georgian Orthodox Church shortly after. [Saintly? The 10 Most Controversial Miracles]
Missing relicsBefore her death, Queen Ketevan had befriended two Augustinian friars who became devoted to her. Legend had it that, in 1627, the two friars secretly dug up her remains and smuggled them out of the country. An ancient Portuguese document suggested her bones were held in a black sarcophagus kept in the window of the St. Augustinian Convent in Goa, India.
But the centuries had not been kind to the church: Part of the convent had collapsed and many valuables had been sold off in the intervening centuries. Early attempts to find her remains failed.
But starting in 2004, Rai and colleagues excavated an area they believed contained the remains and found a broken arm bone and two other bone fragments, as well as pieces of black boxes.
Rare lineageTo find out if the bones belonged to the martyred queen, the researchers extracted mitochondrial DNA, or DNA found only in the cytoplasm of an egg that is passed on through the maternal line.
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'Lost' remains of queen found
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Startup Genome Highlights: Córdoba, Argentina – Video
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Startup Genome Highlights: Crdoba, Argentina
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Startup Genome Highlights: Córdoba, Argentina - Video
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Subaru Legacy STI Genome exhaust – Video
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Subaru Legacy STI Genome exhaust
By: mattypot1
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Subaru Liberty 3RB with STI Genome’s – Video
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Subaru Liberty 3RB with STI Genome #39;s
05 Subaru Liberty 3RB 6MT Wagon with stock exhaust and STI Genome mufflers.
By: Jay Ritchie
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Subaru Liberty 3RB with STI Genome's - Video
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Non-coding DNA implicated in type 2 diabetes
Posted: at 3:47 pm
Jan. 12, 2014 Variations in non-coding sections of the genome might be important contributors to type 2 diabetes risk, according to a new study.
DNA sequences that don't encode proteins were once dismissed as "junk DNA," but scientists are increasingly discovering that some regions are important for controlling which genes are switched on.
The new study, published in Nature Genetics, is one of the first to show how such regions, called regulatory elements, can influence people's risk of disease.
Type 2 diabetes affects over 300 million people worldwide. Genetic factors have long been known to have an important role in determining a person's risk of type 2 diabetes, alongside other factors such as body weight, diet and age.
Many studies have identified regions of the genome where variations are linked to diabetes risk, but the function of many of these regions is unknown, making it difficult for scientists to glean insights into how and why the disease develops. Only around two per cent of the genome is made up of genes: the sequences that contain code for making proteins. Most of the remainder is shrouded in mystery.
"Non-coding DNA, or junk DNA as it is sometimes known, is the dark matter of the genome. We're only just beginning to unravel what it does," said leading author Professor Jorge Ferrer, a Wellcome Trust Senior Investigator from the Department of Medicine at Imperial College London.
In the new study scientists mapped the regulatory elements that orchestrate gene activity in the cells of the pancreas that produce insulin, a hormone that regulates blood sugar.
In type 2 diabetes, the tissues become less responsive to insulin, resulting in blood sugar levels being too high. Most people can compensate when this happens by producing more insulin, but in people with type 2 diabetes, the pancreas cannot cope with this increased demand.
"The cells that produce insulin appear to be programmed to behave differently in people with type 2 diabetes," said co-author Mark McCarthy, a Wellcome Trust Senior Investigator at the University of Oxford. "This study provides some important clues to the mechanisms which are disturbed in the earliest stages of the development of type 2 diabetes, and may point the way to novel ways of treating and preventing the disease."
The team identified genome sequences that drive gene activity in insulin-producing cells specifically. They found that these sequences are located in clusters, and that genetic variants known to be linked to diabetes risk are also found in these clusters.
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Eczema: Bleach bath therapy – Video
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Eczema: Bleach bath therapy
If your child #39;s dermatologist recommends bleach baths, follow these important steps for giving a bleach bath.
By: AcademyofDermatology
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Kangen Water and Eczema – Video
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Kangen Water and Eczema
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Tweaking MRI to Track Creatine May Spot Heart Problems Earlier, Penn Medicine Study Suggests
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Newswise PHILADELPHIA A new MRI method to map creatine at higher resolutions in the heart may help clinicians and scientists find abnormalities and disorders earlier than traditional diagnostic methods, researchers at the Perelman School of Medicine at the University of Pennsylvania suggest in a new study published online today in Nature Medicine. The preclinical findings show an advantage over less sensitive tests and point to a safer and more cost-effective approach than those with radioactive or contrasting agents.
Creatine is a naturally occurring metabolite that helps supply energy to all cells through creatine kinase reaction, including those involved in contraction of the heart. When heart tissue becomes damaged from a loss of blood supply, even in the very early stages, creatine levels drop. Researchers exploited this process in a large animal model with a method known as CEST, or chemical exchange saturation transfer, which measures specific molecules in the body, to track the creatine on a regional basis.
The team, led by Ravinder Reddy, PhD, professor of Radiology and director of the Center for Magnetic Resonance and Optical Imaging at Penn Medicine, found that imaging creatine through CEST MRI provides higher resolution compared to standard magnetic resonance spectroscopy (MRS), a commonly used technique for measuring creatine. However, its poor resolution makes it difficult to determine exactly which areas of the heart have been compromised.
Measuring creatine with CEST is a promising technique that has the potential to improve clinical decision making while treating patients with heart disorders and even other diseases, as well as spotting problems sooner, said Reddy. Beyond the sensitivity benefits and its advantage over MRS, CEST doesnt require radioactive or contrast agents used in MRI, which can have adverse effects on patients, particularly those with kidney disease, and add to costs.
Today, magnetic resonance imaging (MRI)-based stress tests are also used to identify dead heart tissuewhich is the warning sign of future problems (coronary artery disease, for instance)but its reach is limited. MRI is often coupled with contrast agents to help light up problem areas, but it is often not sensitive enough to find ischemic (but not yet infarcted) regions with deranged metabolism, said Reddy.
After a heart attack, different regions of the heart are damaged at different rates. This new technique will allow us to very precisely study regional changes that occur in the heart after heart attacks, enabling us to identify and treat patients at risk for developing heart failure before symptoms develop, said study co-author Robert C. Gorman, MD, professor of Surgery, and director of Cardiac Surgical Research at Penn Medicine.
To demonstrate CESTs ability to detect heart disease, the researchers applied the creatine CEST method in an MRI scanner, in healthy and infarcted myocardium (muscle tissue in heart) in large animals. In the process, the nuclear magnetization of amine (NH2) creatine protons is saturated by a radiofrequency pulse from the MRI. After the exchange with water, the degree of saturation is observed as the water signal drops, and thus the concentration of creatine becomes apparent. (In the body, creatine is converted to creatinine, which can be measured through blood and urine tests and is an important tool for assessing renal function.)
The team showed that the creatine CEST method can map changes in creatine levels, and pinpoint infarcted areas in heart muscle tissue, just as MRS methods can. However, they found, CEST has two orders of magnitude higher sensitivity than MRS. That advantage could help spot smaller damaged areas in the heart missed by traditional methods, the authors say.
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Tweaking MRI to Track Creatine May Spot Heart Problems Earlier, Penn Medicine Study Suggests
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