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Longevity and Anti-senescence Therapy Market Size and Growth Factors Research and Projection 2026 – Farming Sector
Posted: January 7, 2021 at 5:44 am
The Global Longevity and Anti-senescence Therapy Market comprises market size, status, and growth rate for the forecast period 2021-2026. The report offers fundamental data to readers, strategists, senior administration, and advertisers associated with the market. This unique and updated report precisely presents each and every aspect of the Global Longevity and Anti-senescence Therapy industry and represents it in an easy to understandable format. Alongside, researchers have broken down the market into various key verticals. Longevity and Anti-senescence Therapy market also covers industry-oriented drivers, restraints, threats, and opportunities in the market.
North America has a significant international presence in the global Longevity and Anti-senescence Therapy market in 2021 accompanied by the Middle East/Africa, Europe, and the Asia Pacific, respectively.
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The report tracks the global Longevity and Anti-senescence Therapy market competitors, status, share, future trends, growth rate, sales, SWOT analysis, channels, distributors, and development plans for forecast period 2021 to 2026. In addition to this, the import & export status and revenue figures are also added. The report is categorized into key geographical regions, sub-regions, major segments like types and applications.
The thorough Longevity and Anti-senescence Therapy Market research report presents summary of the existing market scene. The report lo focuses on different details on the overall ecosystem, market drivers, major ongoing trends, challenges, threats that directly impact the market progress. After constant observation, evaluation and research initiatives, the updated research is released to ensure better display of the Longevity and Anti-senescence Therapy market picture to help buyers, business, strategists, and individuals get to better conclusions. Furthermore, the research report on Longevity and Anti-senescence Therapy market includes essential analytical opinion on the segment specifications along with the product scenario and its potential in the forecast period.
Major Players in the Longevity and Anti-senescence Therapy Market report included are: Acorda Therapeutics, Unity Biotechnology, Antoxerene, Celgene, Cohbar, Senex Biotechnology, Human Longevity Inc., T.A. Sciences, Agex Therapeutics, Recursion Pharmaceuticals, Calico Life Sciences, Spotlight Bioscience, Powervision Inc., Sierra Sciences Llc, Restorbio, Insilico Medicine, Oisin Biotechnology, Senolytic Therapeutics, Proteostasis Therapeutics Inc., Prana Biotechnology Ltd., Cleara Biotech
Longevity and Anti-senescence Therapy Market Segmentation by Product types:
Applications covered in the report are:
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Key Geographical Regions included in this report: United States, Europe, China, Japan, Southeast Asia, India, Central & South America
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Posted: at 5:44 am
The PGA TOUR and WHOOP, the human performance company, announced a multi-year partnership naming WHOOP as the Official Fitness Wearable of the PGA TOUR and PGA TOUR Champions and a Sponsor of PGA TOUR Active.
To activate the partnership, WHOOP and the TOUR will implement a WHOOP Live for Charity initiative to highlight player biometric data and heart rate during defining moments throughout the season with those real-time metrics integrated into video content. Featured players will receive a $10,000 contribution to the charity of their choice on behalf of WHOOP and the TOUR. Fans can follow these moments at #WHOOPLIVE beginning in 2021.
We are excited to grow our partnership with WHOOP and utilize their health technology to optimize the way our athletes train, recover and sleep, said Brian Oliver, PGA TOUR Executive Vice President of Corporate Partnerships. Our athletes understand the importance of maintaining their health to ensure peak competitive performance, career longevity and overall well-being. The WHOOP Strap will help our athletes unlock actionable insights via physiological data to help them understand and prepare their bodies for competition. Were eager to begin a first-of-its-kind activation at the TOUR that will incorporate player biometric data with defining moments from the golf course to create fascinating content for fans.
This summer upon the TOURs return to golf over 1,000 WHOOP Straps were distributed for players, caddies and other essential personnel at PGA TOUR, Korn Ferry Tour and PGA TOUR Champions events, with accompanying membership for health monitoring. WHOOP collects physiological data that helps an individual optimize workouts, recovery and sleep and can identify changes in respiratory rate with industry-leading third party validated accuracy. This official partnership is a natural evolution from the collaborative efforts to find new solutions to support TOUR athletes at all levels.
WHOOP has organically grown amongst the worlds best golfers for years and we are proud to take our relationship with the PGA TOUR and all athletes to the next level, said Will Ahmed, WHOOP Founder & CEO. This partnership is particularly new and innovative in that it will bring heart rate and other engaging physiological metrics directly into the fan experience.
WHOOP will activate and create custom content within PGA TOUR Active (www.pgatour.com/active), a new TOUR initiative highlighting health, fitness and lifestyles of professional golfers, where fans get an inside look into the techniques and activities helping the best players in the world perform at their peak.
Throughout the partnership, PGA TOUR, PGA TOUR Champions and Korn Ferry Tour players and trainers will receive the latest products and technology from WHOOP to assist in monitoring their health. WHOOP will have an amplified onsite presence at all PGA TOUR events to provide VIP support and incorporate that technology with training and recovery staff on the PGA TOURs state-of-the-art Player Performance Centers that travel to PGA TOUR and PGA TOUR Champions events and bring state-of-the-art fitness equipment and care to its athletes throughout the season.
I've been a WHOOP member for a number of years and having the ability to monitor my recovery on a daily basis is helpful for my overall performance. WHOOP has been everywhere on TOUR in 2020 and this new partnership will unlock the future of athletic performance and professional golf, said Rory McIlroy, WHOOP Investor and PGA TOUR member. And now fans will have access to player data that will change the way they experience and engage with the game.
Posted: at 5:44 am
It is estimated the world will invest 94 trillion U.S. dollars in infrastructure globally in the next 20 years. With that level of investment, we should ask some important questions. What is the best approach we should use today to deliver these projects? How can we incorporate climate change, social equity, and sustainability into our project planning? What is the future of our engineering practice?
One thing 2020 has taught uswe cant solve problems as we did before. Todays infrastructure investment must include new thinking. Through innovation, every project, regardless of sector, needs the longevity to last several decades and incorporate forward-thinking innovations to solve future challenges today. We must start to apply green box thinking.
Rami Issa, AECOM
Cities, developers, architects, and engineers are increasingly looking for ways to move away from the concrete jungle and incorporate elements of nature into our everyday lives. This focus on more sustainable development is the same approach we should take when evaluating infrastructure.
Many of us are familiar with gray infrastructurethe more traditional, concrete, human-engineered solutions however, green infrastructure is a solution worth exploring and implementing alongside gray infrastructure. It refers to natural elements of our ecosystem, such as forests, reefs, and wetlands, which can serve many of the same gray infrastructure functions.
When you blend both green and gray infrastructure together, the result is a cohesive solution that helps address community resiliency future challenges. In many instances, incorporating green infrastructure into future infrastructure investments may boost eco-tourism and generate new revenues for local communities.
Green infrastructure can take many forms, from protected natural areas to green roofs in cities. The goal is to employ nature to provide natural benefits such as clean air or reliable flows of clean water. By blending conservation and restoration techniques with innovative engineering, green-gray infrastructure provides solutions enabling communities to mitigate natural disasters and adapt to a changing climate. However, the challenge is strategically combining the two.
To further advance the science and practice of green-gray infrastructure, the Green-Gray Infrastructure Community of Practice (GGI COP) was established. It will blend conservation and restoration of nature with human-made engineering approaches to fortify communities against climate effects.
AECOM co-founded the initiative with Conservation International, a global leader in environmental conservation and sustainable development. Conservation International plans to release a practical guide for GGI implementation, which will be a tool for engagement with local governments, clients, universities, and field staff to support project implementation.
Flooding resiliency is one area where green-gray infrastructure can help provide a solid solution. GGI COP estimates the number of people impacted by floods will double worldwide by 2030. While conventional engineering approaches of upsizing stormwater conveyance and storage systems may have near-future benefits, they do not incorporate future challenges such as climate change and social and economic shifts. These projects can be very costly to construct, and stop-gap solutions only kick the can down the road.
Flooding continues to be a challenge in North Texas, and tackling it head-on requires a new way of thinking. Collaboration and partnerships among many stakeholders in our North Texas community must deliver integrated infrastructure solutions that incorporate green and gray infrastructure together. These solutions should incorporate regional transportation, stormwater management, and environmental planning into regional infrastructure projects.
Now, how do we blend green and gray infrastructure solutions? We do it by adding purpose, beauty, value, equity, and resiliency through each project by transforming the way we perform integrated planning and design.
Integrated planning and design have the power to transform a community into the next level and incorporate restorative environments within urban density. A shift from reactive planning into a proactive planning approach will solve todays challenges and account for future challenges. This is the future of practice, no doubt.
Rami Issa is the DFW Water Business Line Leader at AECOM.
Here is the original post:
The New Face of Integrated Planning and Design - D Magazine
Posted: at 5:44 am
The MO of fast fashion brands is to mass-produce trendy designs at a low cost. While some brands are working on a greener selection, we know that greenwashing, waste, and human rights violations abound in the fashion industry.
Emma Mathews, founder of the sustainable British sock brand Socko and author of How to Quit Fast Fashion: 100 Expert Tips for a Sustainable Wardrobe advised us on how to take meaningful steps towards quitting fast fashion.
Clothing is more than the sum of its materials. Behind every garment are people, water, agriculture, energy, and transportation emissions, and much more.
The fashion industry produces more carbon emissions than international flights and maritime shipping combined, and is the second-largest consumer of the worlds water supply despite this, 85% of all textiles end up in the dump each year. How to Quit Fast Fashion
In Mathews view, the hazards of fast fashion are greatest for textile and garment workers and the environment. Clothes dont magically appear. Think about the number of hands that handle that garment before it gets to you, about how much you pay versus what the person is paid after retail and shipping costs for something designed to be throwaway.
Garment makers work in appalling conditions because retailers, to satisfy demand, prioritize low-cost clothing over peoples lives. One of the starkest examples is the 2013 Rana Plaza fire in Bangladesh, the fourth largest industrial disaster in history, during which 1,100 people died and another 2,500 were injured.
Reevaluating your relationship with fast fashion means reconciling with the environmental and human costs, but Mathews is adamant that preaching isnt the goal. On the contrary, its about providing tools so consumers can make the decision for themselves.
Even if we stopped production tomorrow, we have enough to clothe the next two generations, says Mathews.
So, its not that we need more clothes its that were bored with what we have.
Lessening your clothings impact on our ecosystem doesnt have to mean sacrificing style.
Its in your hands as a consumer to take care of your clothing. Instead of buying new, learn fundamental preservation principles from way back when.
Paying a fair price for clothing does mean it will be more expensive, Mathews says. Thats why consumers have to make a mindset shift between wanting a quick pick-me-up and thinking for all seasons.
What makes it onto the clothing racks represents a give and take between brands and consumers. Since our closets dont exist in a vacuum, both have a vested interest in designing for a circular economy and wearing for the long-term.
Mathews believes retailers should educate consumers about the longevity of their items, and that we need legislation to regulate the fashion industry and protect garment workers. Changing consumer preferences are already making a positive impact, but theres no quick fix.
Thats why brands, as well as consumers, must continue probing the way clothing production and consumption are interlinked. If you want to have a sustainable business and lifestyle, How can you justify against what the planet needs?
Program Expansion to Address Increase of Impaired Driving During Global COVID-19 Pandemic – UC San Diego Health
Posted: December 26, 2020 at 12:55 am
Researchers at University of California San Diego School of Medicine will expand a statewide program to prevent driving under the influence of alcohol, cannabis and prescription drugs. With funding from the California Office of Traffic Safety through the National Highway Traffic Safety Administration (NHTSA), the UC San Diego Training, Research and Education for Driving Safety Program (TREDS) provides education and resources to teach the public about the dangers of driving under the influence of alcohol and drugs in an effort to keep our roadways safe.
In addition to alcohol, driving under the influence of cannabis and certain prescription or over-the-counter medications has rapidly become a serious traffic safety issue in the United States, especially during the global COVID-19 pandemic.
Linda Hill, MD, MPH, program director of TREDS and professor of family medicine at University of California San Diego Herbert Wertheim School of Public Health and Human Longevity.Photo Credit: UC San Diego Health Sciences
An NHTSA study conducted at five hospital trauma centers between March and July of 2020 found that nearly two-thirds of seriously or fatally injured road users tested positive for at least one active drug, including alcohol, cannabis or opioids. The number of drivers that tested positive for opioids or cannabis dramatically increased after mid-March compared to the previous six months.
Stress, anxiety and depression are serious mental health concerns during the pandemic, and some are turning to alcohol, drugs and opioids to manage their emotions and then getting behind the wheel, said Linda Hill, MD, MPH, program director of TREDS and professor of family medicine at University of California San Diego Herbert Wertheim School of Public Health and Human Longevity. Collisions due to driving under the influence are 100 percent preventable. Our behavior profoundly influences our crash risk. We can reduce this risk by providing intervention strategies.
TREDS develops traffic safety education programs and conducts train-the-trainer workshops to prepare law enforcement and health professionals to teach classes to the public. The focus of this years program includes the following:Delivering virtual workshops on a monthly basis with the goal of training professionals in every county in California. This is a major expansion from previous years, said Hill. The workshops will feature curricula that address the topics of distracted driving, pedestrian safety, older road user safety and driving under the influence of alcohol, cannabis and medications.Linking organizations, groups and educational institutions with professionals in their communities who have received training to deliver these prevention programs.
Experts like Hill remind the public that the potency of todays cannabis has increased dramatically in recent years and affects each person differently. The peak effect for smoking THC is approximately 10 minutes after inhaling and can last four to eight hours. For edibles, the peak effect may occur up to two hours after ingesting and may last 10 hours or longer.
Impairing effects are based on the strength of THC, personal tolerance and mode of use, said Hill. It is critical that we continue to collaborate with those on the frontlines of road safety and the health professionals who see the tragic results of impaired driving in our emergency room settings, so we can have a unified message to our community to drive safely and sober, alcohol and drug free.
For more information, to request a training or locate a class instructor, contact TREDS at 858-534-8386 or email@example.com.
Funding for this program was provided by a grant from the California Office of Traffic Safety, through the National Highway Traffic Safety Administration.
Posted: at 12:55 am
Since 1961, more than 500 humans have flown into space. However, only 20 astronauts have stayed more than 90 days on long-duration space missions. If humans will one day travel to and from Mars, the round-trip will take 3 years. It is essential then, before those crew members ever launch, that we understand the effects long duration spaceflight has on the human body.
This unique environment consists of extreme conditions such as weightlessness, high radiation, variations in extreme temperature and pressure, among other health stressors. Long duration space flight significantly affects astronaut body mass index and what genes are expressed. Changes in metabolism, vascular health, the gastrointestinal microbiome, and cognitive performance were also observed during spaceflight. These adverse effects resolve upon return to earth as astronauts maintain vigorous exercise and nutrition programs for rehabilitation.
To study in depth the changes taking place in the human body over such a long mission in space, researchers need to look at everything from genetics to body mass. Among the Astronaut corps, NASA had a unique opportunity a set of genetically identical twin astronauts, Scott and Mark Kelly. For 340 days, Scott would be on the International Space Station (ISS), while Mark remained on Earth, both undergoing the same medical analyses, pre-flight, in-flight, and post-flight to catalog the changes between the two.
The results were obtained from samples including saliva, stool, skin, urine and blood. Different molecular level techniques, cognitive tests, and biometric tests were used to understand the genetic, physiological and psychological changes in the astronauts.
The astronauts experienced changes in the expression of over 800 genes during spaceflight. Most of the genes returned to normal after flight, but some did not leading to changes in astronauts genetics and physiology. Space radiation may have damaged their DNA.
The midflight flu vaccination administered by the astronauts worked exactly as it does on Earth. This suggests the primary immune system functions were maintained during the flight, and vaccines were still an effective tool for protection.
Genes related to inflammation were more active, which may result from the human body reacting to long duration space flight. Researchers suggest telomeres (a region of DNA at the end of a chromosome) act as an aging clock in every cell, as we grow older our telomeres grow shorter. Telomere elongation was observed in space, but we cannot conclude that space is a miraculous location that adds to human longevity. Elongation may be due to the exercise and calorie-regulation astronauts maintain inflight.
A rapid shortening of telomeres in less than 45 hours was observed upon astronaut return to Earth, likely due to the extreme stresses associated with landing. Mainly the longer telomeres are associated with healthy lifestyle factors such as good nutrition and regular physical activity. However, it is unknown if telomere lengthening and shortening relate to aging in this case, because of the lack of research conducted on telomeres in microgravity.
Spaceflight might have effects on learning and cognition. The in-space astronaut could complete learning and work tasks with greater speed and accuracy, concluding that spaceflight may affect cognition positively.
Bone density is of great concern for space biology researchers. It is well known that spaceflight causes rapid loss of bone density, decreased muscle mass, and weight loss. These are common physiological changes observed in astronauts due to changes in gene and hormone regulation in space. Furthermore, due to microgravity, blood and fluids move from lower to upper body called headward fluid shift causing an appearance of a puffy face and skinny legs. This fluid shift may lead to increased pressure in the veins and capillaries of the eyes causing vision problems in astronauts.
Research also suggests astronauts are at high risk for dehydration, evidenced by changes in the gene AQP2, which regulates water reabsorption in the body and is a useful indicator of hydration status. On the ISS, the isolated and confined environment of the astronauts puts them in a degree of psychological stress. Meanwhile, eating only freeze-dried or heat-stabilized prepackaged food in space is different from what astronauts are used to eating on Earth. These psychological and nutritional stressors in astronauts negatively affect the function of beneficial gut microbes. This change in the gut microbiome results in alterations of immunity, physiology, and even psychological well-being.
The NASA twin study generated unique biomedical data on the effect of a year-long spaceflight on the human body. Most of the biological changes returned to baseline after the 340-day space mission, suggesting that human health can be mostly sustained over this spaceflight duration. As the researchers suggest, the space environment leads to potential health risks. Exercise, a good diet, and personalized medicine will make multi-year space exploration safe for astronauts. These advancements also have the potential to improve Earth medicine as well.
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How does the human body react to being in space? - Sciworthy
Posted: at 12:55 am
As we look forward to 2021, many of us have started to think about New Year's resolutions. For those of us looking to lose weight over the next twelve months, a brand new diet can not only help us hit our weight loss goals, but also introduces us to new foods, raises our energy levels, and helps us live longer, more fulfilled lives. And yet, if you decide to embark on a brand new diet, figuring out which plan to follow can feel mind-boggling. Trying to sort between the best diets to live longer and the not-so-great fad diets only makes losing weight that much harder.
So if you feel overwhelmed by the world of dieting and have no idea of where to start, have no fear! To help streamline your weight loss process and guarantee a long and healthy life, we talked to a wide range of registered dietitians, nutritionists, and medical doctors to assemble the top six diets that help you live longer. By eating healthy and exercising regularly, you can stay one step ahead of weight gain and keep moving for decades to come.
Read on to learn which six diets can help you live longer, and for even more healthy tips, be sure to check out our list of The 7 Healthiest Foods to Eat Right Now.
"The Mediterranean diet has consistently been ranked by US News & World Report as the world's best overall diet," says Lexi Endicott, RD, LD, and culinary nutrition specialist for To Taste. "Rather than a diet in the traditional sense in which you go on it to eventually go off it, the Mediterranean Diet is a simple and sustainable eating pattern that can be followed for life. This eating pattern emphasizes consuming a variety of plant foodsa plant-forward diet, so to speak."
If you feel ready to take the plunge, the nutritional benefits of this eating plan can keep you healthy for years.
"These healthful foods [and] ingredients are rich in vitamins, minerals, and phytochemicals (i.e. antioxidants) that decrease risk of developing many chronic diseases such as heart disease, cancer, diabetes, and Alzheimer's," says Endicott. "The more disease-free years someone can add to their life, the better!"
If you want to really super boost your chances for longevity, check out our list of 20 Foods You Should Be Eating Every Day for a Longer Life.
Eating less can definitely help you lose weight, but it might also keep you around much longer.
"The diet that has the most empirical evidence in regards to increasing life expectancy is intermittent fasting or even fasting in general," says Dr. Alexander Lightstone Borsand, MD. "Animal studies have shown that the less often animals eat, the longer they live in comparison to animals fed more regularly. The most notable study in humans followed 2,000 patients after cardiac catheterization and showed an increased lifespan in patients who regularly fasted."
"Another animal study showed that mice that were fed once a day had an 11% increase in lifespan as compared to the mice fed multiple times a day," says Dr. Borsand. "This is a significant increase in lifespan and warrants further human studies."
Here are7 Science-Backed Benefits of Intermittent Fasting.
If you haven't heard of the DASH diet, get ready for an eating plan that can change your life. The Dietary Approaches to Stop Hypertension diet encourages the consumption of foods that lower blood pressure has taken off in recent years, and can do some wonders.
"The science is very clear that a plant-based or plant-forward diet is quite remarkable for its positive impact on longevity and healthspan," says Dr. Nicole Harkin, MD, FACC, founder and cardiologist of Whole Heart Cardiology. "This diet is high in vegetables, fruits, whole grains, legumes/beans, nuts, and seeds while minimizing or eliminating animal products and processed packaged foods."
"Numerous epidemiologic studieshave demonstrated that an increased intake of plant-based foods results in reduced risk of cardiovascular and other causes of death," says Dr. Harkin. "We also see a decreased risk of obesity, high blood pressure, high cholesterol, diabetes, and inflammation. While not all individuals may not be ready to go completely plant-based, working on incorporating as many plant-based foods and #meatlessmondays is a great first step!"
Here is Everything You Need to Know About the DASH Diet.
What do Greece, Japan, Italy, California, and Costa Rica have in common? These areas constitute Blue Zonesareas of the world with the highest concentration of centenarians. In order to live like someone who could reach 100, you need to eat like someone who can reach 100, and this diet helps you do just that!
"The Blue Zones have several lifestyle factors in common which appear to contribute to the longevity and increased likelihood of living to 100 years of age," says Dr. Christine Bishara, MD, founder of From Within Medical. "Their diets are composed of fresh whole foods which are primarily plant-based and also include nuts, legumes, and olive oil. They incorporate minimal red meat with the majority of the animal protein components coming from pescetarian options."
They do not eat heavy meals late in the day or close to bedtime," says Dr. Bishara. "They practice socially based eating and have strong ties to their community. This has been studied numerous times as a major factor in longevity including another study called 'The Roseto Effect'[ and] they live in areas with ease of daily walking as a form of exercise. This seems to also be another well-studied contributor to longevity."
People in the blue zone typically eat this One Food You Should Be Eating Every Day For a Longer Life.
"Though it sounds like the latest trend, the carnivore diet is a diet that was followed for ages," Dr. Rashmi Byakod said. "The human race evolved from eating raw and cooked meat. In the olden days, there was no agriculture, and plant food was the least consumed. Meat foods are highly nutritious and carry numerous health benefits."
If you ever considered yourself a "meatatarian" you might actually be onto something.
"The aging process indicates impairment of mitochondrial function, reduced antioxidant effect, and increased oxidative stress," says Dr. Byakod. "Selenium and Coenzyme Q10 (CoQ10) present in meats have antioxidant effects helping in longevity and wellbeingOther than these, meats are a good source of vitamin D, omega 3 amino acids, and various other nutrients. Adapting to a carnivore diet can help you meet all the nutritional requirements of your body."
If you love the idea of the Mediterranean diet, but don't want to cut our dairy, this diet will make you swoon.
"Dairy, especially full-fat dairy, contains healthy fats, calcium, and other nutrients that are recommended for a healthy diet," says Lisa Richards, CNC. "It is easy to integrate more servings of dairy into the traditional Mediterranean diet through cheeses, yogurt, and dairy-based sauces."
"Adding dairy to the Mediterranean Diet could make it more sustainable long-term, especially for women who need the added calcium and vitamin D," says Richards. "The fat content may deter some people as it adds additional fat to an already moderate fat diet, however, easy exchanges can be made to ensure a balance of fish and plant fat with added dairy."
"As with any diet, moderation is important," says Richards. "The foods recommended on the Mediterranean Diet are not shown to be unhealthy for your heart. However, the dieter should make sure they are still staying within their calorie limits, especially with fat content, to avoid any negative side effects."
For more on the Candida Diet: This Is Everything You Should Eat and Why, According to Experts.
Here is the original post:
The 6 Best Diets That Will Make You Live Longer, Say Dietitians - Eat This, Not That
Posted: at 12:55 am
Several microplastic particles were found in the placentas of pregnant women for the first time, according to a new study.
Researchers behind the study published in the journal Environment International analyzed six human placentas from healthy pregnant women in Italy to search for the presence of microplastics.
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To ensure the placentas researchers were analyzing were not contaminated with plastics after leaving the body, a plastic-free environment was maintained over the course of the experiment. Obstetricians and midwives used cotton gloves to assist the women while in labor and only cotton towels were used to cover patientss beds. The umbilical cord was clamped and cut with metal clippers and pathologists wore only cotton gloves.
Scientists found 12 microplastic fragments ranging from 5 to 10 micrometers in size in four of the placentas collected after the women gave birth. Researchers said all the particles that were analyzed were pigmented and may have originally come from packaging.
Three were identified as stained polypropylene a thermoplastic polymer, while for the other nine it was possible to identify only the pigments, which were all used for man-made coatings, paints, adhesives, plasters, finger paints, polymers and cosmetics and personal care products, researchers wrote in the study.
While the healtheffects of microplastics in the body is still largely unknown, the study notes the particles could carry chemicals that cause long-term effects on human health and more research on the issue is needed.
Due to the crucial role of placenta in supporting the foetus development and in acting as an interface between the latter and the external environment, the presence of exogenous and potentially harmful (plastic) particles is a matter of great concern, researchers wrote.
Microplastics are tiny plastic particles less than 5 millimeters long that originate from a variety of sources, including debris from large plastic items that have been broken down over time into smaller pieces. Other types of microplastics are manufactured for commercial use in cosmetics and other products.
Microplastic pollution has been found in the deepest parts of the ocean and are a threat to marine animals and birds that mistake microplastics for food and ingest them. Recently, microplastic fragments were found near the summit of Everest.
The study notes that over the last century, the global production of plastics has hit 320 million tons annually, with more than 40 percent used as single-use packaging.
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Medicine by Design symposium highlights importance of convergence in regenerative medicine and human health – News@UofT
Posted: at 12:55 am
Researchersarepoised to makeunprecedentedbreakthroughsinhuman health thanks toadvancesin biomedical and computational sciencesthathave drivencritical tools and technologiessuch as genetic engineering,synthetic biology, andartificial intelligence.
Thats the messageDr. VictorDzau, president oftheU.S.National Academy ofMedicine, delivered to Medicine by Designs fifthannual symposium on Dec. 7 and 8.
Thevirtual event, whichattracted more than 500 registrants from across North America, focused on the theme of better science throughconvergence theintegration of approaches from engineering, science, medicine and other fields to expand knowledge and spark innovation.
I think for younger people, there is really not a more exciting time, in my opinion, to do research than now, because we can really see that some of the initial concepts that people have about health and medicinecan be realizedand truly transform the way we do health andmedicine.
In his talk, Dzau focused on the National Academy of MedicinesHealthy Longevity Global Challenge,an international competition that aims to catalyze transformative ideas and breakthroughs that will extend human healthand lifespan.
That program is one of the inspirations for Medicine by DesignsGrand Questions Program, which seeks to fund bold research that promises dramatically better health outcomes by changing the future of regenerative medicine.
Through our Grand Questions Program, we are thinking about what comes next and how to overcome fundamental problems in regenerative medicine,saidMichael Sefton, executive director of Medicine by Design andUniversity Professorin the department of chemical engineering and applied chemistry and theInstitute of Biomedical Engineeringat the University of Toronto.
We have a broad definition of regenerativemedicine, andpreventing degeneration can be as important as the next cell therapy.
Sefton pointed out that the symposium theme of better science through convergencefocusedon a key aspect of Medicine by Design:That we combine campus and hospital investigators, transformative science and translational elements, junior and senior investigators, and local and international collaborators, to address fundamental problems in regenerative medicine.
Thesymposium also featured a talk byRobert Langer, David H. KochInstitute Professorin the department of chemical engineeringat the Massachusetts Institute of Technology. The most highly cited engineer in history, he spoke about lessons helearnedfromhisscientific and business successes and how he decidedto be his own champion after facing criticism for his novel ideas early in his career.
If you try to do things whether its convergence, or things that a lot of people disagree with you have tohang in there, Langer said.Having good intellectual property has been key toraising the funds to do these things, and medicine is an incredibly expensive thing.
And finally, you really need teams that are super driven, and I think these startup companies have been a wonderful way to do this.
The symposium was organized around four sessions: translation, inflammation, biomaterials andimmunoengineering.Invited speakers from across North AmericaincludedKim Warren(AVROBIO),Kenneth Walsh(University of Virginia),Sarah Heilshorn(Stanford University)andMegan Levings(University of British Columbia).
All speakers fromU of T and its partnerhospitals were lead investigators on Medicine by Designs multi-disciplinary, multi-institution team projects. They included:John Dick,Clinton RobbinsandShaf Keshavjee(University Health Network (UHN));Molly Shoichet(department of chemical engineering and applied chemistry and Institute of Biomedical Engineering);Juan CarlosZiga-Pflcker(Sunnybrook Health Sciences Centre);andAndras Nagy(Sinai Health System).
Ted Sargent, vice-president of research and innovation, and strategic initiatives,and a University Professor in the Edward S. Rogers Sr. department of electrical and computer engineering,opened the symposium by congratulatingMedicine by Design on its successful mid-term review, which was conducted in early 2020 by a panel of international experts and theCanada First Research Excellence Fund(CFREF), which funds Medicine by Design.
Medicine by Design has amplified existing areas ofexcellenceatU of Tandour partner hospitals (Toronto Academic Health Sciences Network),and pushed the boundaries of regenerative medicine to tackle cell-based therapies, strategies for endogenous repair and the use of a stem cell lens to target the triggers of disease,Sargent said. In fact, Medicine by Design is such a compelling collaborative, cross-disciplinary initiative that itis a template fora new class of initiatives at the University ofToronto theInstitutional Strategic Initiativesportfolio whosepurpose is to mobilize ambitious,groundbreaking, collaborative, multi-institutional research networks that tackleimportantresearch problems, buildmajorexternal partnershipsboth with industry and emerging companies as well as with global academic peers;and foster societal impact.
They support the pursuit of grand challenges and bold ideas across disciplinary boundaries,further elevate U of Ts profile in high priority research areas of strategic importance,and enable us to realize transformational impacts on issues of major societal import.
The symposium also offered an opportunity for almost 45trainees to present their research during a poster session.KerstinKaufmann, a post-doctoral fellow in the laboratory ofJohn Dick(Princess Margaret Cancer Centre,UHN), won first place.JonathanLabriola, apost-doctoral fellowinSachdev Sidhuslab(Donnelly Centre for Cellular and Biomolecular Research, U of T), placed second, whileSabihaHacibekiroglu, a post-doctoral fellow in the lab ofAndras Nagy(Lunenfeld-Tanenbaum Research Institute, UHN)placed third.The awards were sponsored by STEMCELL Technologies.
YasamanAghazadeh,a post-doctoral fellow in the labsofCristina Nostro(McEwen Stem Cell Institute, UHN)andSara Nunes Vasconcelos(Toronto General Hospital Research Institute,UHN),won theCCRMTranslation Awardfor the poster with the greatest translational potential.AndAi Tian, a post-doctoral fellow fromJulien Muffatslab (The Hospital for Sick Children), won thePeoples Choice Award, a new award this year that wasdetermined byvotingby symposium attendeesand sponsored byBlueRockTherapeutics.
Funded by a $114-million grant from CFREF, Medicine by Design brings together more than 145principal investigators at the University of Toronto and its affiliated hospitals to work at the convergence of engineering,medicineand science. It builds on decades of made-in-Canada excellence in regenerative medicine dating back to the discovery of stem cells in the early 1960s by Toronto researchers James Till andErnest McCulloch.
Regenerative medicine uses stem cells to replace diseased tissues and organs, creating therapies in which cells are the biological product. Regenerative medicine can also mean triggering stem cells that are already present in the human body to repair damaged tissues or to modulate immune responses. Increasingly, regenerative medicine researchers are using a stem cell lens to identify critical interactions or defects that prepare the ground for disease, paving the way for new approaches to preventing disease before it starts.
(Photo of Robert Langer by Jason Alden)
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Medicine by Design symposium highlights importance of convergence in regenerative medicine and human health - News@UofT
Posted: at 12:55 am
Pet adoption rates have skyrocketed during the pandemic. And the owners of an all-natural dog nutrition brand that started out with a homemade recipe for a senior dog are winning big.Brutus Broth has inked deals with major retailers like Target, Petco, Chewy.com, and thousands of boutique pet stores nationally.
Small Business Trends contacted Kim Hehir and Sue Delegan, founders of the successful small business. We wanted to find out how they turned love and grandmas bone broth, into an expanding enterprise.
The story starts in a place everyone can relate to. With the love of a dog.
It all began on Thanksgiving Day 2016 when a family member asked what we attributed Brutus longevity to, Hehir says.
As a pup the company namesake had a very active life. Then, like most older dogs, Brutus developed health issues. The partners explained how they tackled the issue.
We found that adding bone broth to his diet provided him with a tastier, more easily digestible meal, Delegan says. It also gave him added nutritional benefits.
The result was a successful startup. According to the cofounders, their product adds tasty nutrition to your pets diet in an easy convenient way. The compassionate approach the two started the business with led them to make their product different in big ways.
From a product perspective, we brought something to market that the pet industry hasnt seen before, she says. Brutus Broth is of a higher quality than most human broths on the market. And its the only one fortified with glucosamine and chondroitin.
Theres more to the lengths they went to in developing it. The result is a product thats different from the competition.
We worked with a team that develops nutrient broths for over forty hunger relief organizations feeding third world countries, Hehir says. First and foremost, we produced a high quality, human grade product that is fortified with supplements. Our entire positioning is centered around accessibility.
The Brutus Broth Company knew how to market, too.
We went after the grocery market first, Hehir says. There were no other pet food toppers of our quality offered in grocery stores.
Brutus Broth has the right recipe to make it. They enjoyed initial success selling the product on grocery store shelves until COVID-19. Then the company made a move thats getting more and more familiar in these uncertain times.
When the pandemic hit, we had to quickly pivot to add new distribution channels, Delegan says. Consumers shopping habits had changed and we wanted to stay competitive and top-of-mind. So we shifted to a more digital focus and made a greater push online.
They also had some good fortune working for them. The ingredients for Brutus Broth are American-made so they didnt get hit hard by any supply chain issues. Being classified an essential service by Amazon also helped their fortunes. But there was one more surprise Delegan didnt see coming.
What we didnt foresee was that the pandemic would cause such a rise in pet adoptions. That was a nice surprise, she says.
The company also owes their success to a socially responsible attitude. Hehir explains,We pride ourselves on giving back and have incorporated a robust philanthropic platform Weve developed the Brutus Broth Kids Committee to educate kids about entrepreneurship. And we are members of the Pet Sustainability Coalition.
The pair had some good suggestions for small businesses struggling through the pandemic.
They took the time to put together customer data and metrics. These showed retailers how Brutus Broth fit in with their product mix.
Make your business case as to why a retailer should carry your product. People arent going to buy it because YOU think you have a cool idea. You need to demonstrate how your product solves problems.even the ones they dont realize they have yet.
Hehir supplies some final advice:We stayed focused and persistent when building the relationships.
Originally posted here:
How One Pet Business Boomed During the Pandemic - Small Business Trends