Category Archives: Eczema

Will John Turturro be getting back into the eczema skin of The Night Ofs New York City criminal attorney John Stone soon?

In the series debut season, Stone was thrust into the biggest case of his career defending Pakistani-American college student Nasir (Riz Ahmed) accused of murdering his one-night stand. Now the character is poised to make a comeback.

We have a couple of ideas but we have to sit down and discuss them, so were at that stage so thats good, Turturro told Deadline about a second season of the limited series with co-creator Richard Price.

James Gandolfini originally played Stone in the pilot before Turturro took over following The Sopranos actors death. The show, based on the BBC drama Criminal Justice, was a passion project for Gandolfini, who is credited as an EP on the series set in a culturally divided New York City 15 years after 9/11.

HBO @ TCA: Deadlines Complete Coverage

The Night Ofracked up 13 Primetime Emmy nominations including Best Limited Series, with both Turturro and Ahmed nominated for Lead Actor in a Limited Series (Ahmed won).

Also upcoming for Turturro is hisBig Lewbowskispinoff movieThe Jesus Rollswhich he directed and in which he reprises his Hispanic character from the Coen Brothers movie. Jesus Rolls will be released Feb. 28 from Screen Media.

In regards to Turturros next feature directorial, I have something else said the actor to Deadline today at TCA, but opted to keep mum.

See more here:
John Turturro On The Future Of HBOs The Night Of TCA - Deadline

If youre constantly scratching at itchy skin, priority No. 1 is finding something (anything!) that will make it stop. To do that, its essential to cater your treatment to the reason why youre itching in the first place, explains Melanie Grossman, M.D., a board-certified dermatologist based in New York City.

After all, if you load up on an antihistamine like Benadryl but dont get rid of whats triggering your itch (think: dry skin or insect bites), no number of pink pills will fully relieve your need to scratch.

Sometimes, finding out whats at the bottom of an itch requires the professional insight of a dermatologist. Other times, you can figure it out on your own. Then, get sweet relief with one of these effective, proven treatments for itchy skin.

For dry, itchy skin from cold weather, hormonal fluctuations (blame pregnancy, menopause, or aging), diabetes, and other conditions, a daily moisturizing routine can help rehydrate your skin and, in turn, soothe your itchiness. Opt for a fragrance-free moisturizer, such as EltaMDs Intense Moisturizer or CeraVe Moisturizing Cream, suggests Melissa Kanchanapoomi Levin, M.D., a board-certified dermatologist and founder of Entire Dermatology in New York City.

For an added cooling effect, which helps calm itch-inducing inflammation, try keeping some moisturizer in your fridge before slathering it on, per the American Academy of Dermatology (AAD).

Heres an easy itch treatment: 10 to 15 minutes of quality time with an ice pack, suggests Dr. Kanchanapoomi Levin. Rather than scratching bug bites like theres no tomorrowand dialing up the unpleasant reaction as a resulttry pressing an ice cube to them for quick (albeit, short-lasting) relief, adds Dr. Grossman.

Got itchy skin from insect bites, sunburn, or not-so-nice plants such as poison ivy or oak? Over-the-counter lotions, creams, and gels that contain plant-based herbal remedies such as menthol, calamine, and aloe vera can help reduce inflammation and soothe the skin, says Alix J. Charles, M.D., a board-certified dermatologist and fellow of the AAD.

Ever take oatmeal baths as a kid? Research shows colloidal oatmeala finely-ground type of oatmealcan help lower the intensity of itchy skin as it tamps down inflammation, per a 2015 study in the Journal of Drugs in Dermatology. Soak it up in the tub, apply it to itchy patches in paste-form, or lather it on in a moisturizing lotion or cream.

CeraVe Moisturizing Cream

Aveeno Soothing Bath Treatment with 100% Colloidal Oatmeal

Cortizone-10 Anti-Itch Ointment

Allegra Adult 12 Hour Allergy Relief

To spot-treat itchy skin, try over-the-counter 1% hydrocortisone cream, suggests Dr. Charles, which will work to reduce redness and swelling in addition to itching. If youre dealing with an itchy area youre not so keen to touch or rub, you can also use a hydrocortisone spray, per the Mayo Clinic.

When your bodys immune system alarm bells go off, that can result in a release of itch- and rash-inducing compounds called histamines. Thats where antihistamines come in, which prevent these pesky substances from wreaking havoc on your cells. Take Allegra or Zyrtec to clear up hives and itchiness alike, suggests Dr. Kanchanapoomi Levin.

If youre facing a fast-spreading rash or antihistamines arent making a dent in your symptoms, head for the doc ASAP. It could be a sign of a serious allergic reaction.

If your itch is *really* bad (think: worst poison ivy of your life, extensive hives, or a flare-up from a skin condition like eczema), dermatologists might choose to prescribe stronger treatments, including steroid cream or pills, explains Dr. Grossman. If youve tried a handful of home remedies and theyre not doing the trick, head to your doctor who can help ID next steps.

Again, a super-relentless itch might call for an additional expert treatment, including an injectable medication, says Dr. Grossman. This in-office procedure can help dial down the itch from issues such as contact dermatitis (what happens when your skin has rubbed up against an irritating substance such as poison ivy or a chemical) or a severe case of a skin condition such as eczema or psoriasis.

Keep in mind, though, this treatment can trigger whats known as the rebound effect (meaning symptoms can worsen when treatment is discontinued), so its best to ask your dermatologist about this and any other side effects to consider, according to the National Eczema Association (NEA).

If youve been feeling overwhelmed, andeven worsenow you have a concerningly itchy skin, your mental health could be suffering. While rare, sometimes itchiness can be triggered by the chemicals serotonin and norepinephrine inside your body, as a result of a high-stress situation, anxiety, or depression. Sometimes psychiatric medications, including antidepressants can help soothe your itch, so make an appointment with your physician if you think this may be the case, suggests Dr. Charles.

If youve recently had surgery or youre recovering from an injury, pain medications such as opioids (among others) can cause *big-time* itching as a side effect, says Dr. Grossman. Sound familiar? Adjusting your dose or adding on an anti-itch medication can bring relief.

An in-office procedure called phototherapy (also known as light therapy) can help alleviate itching from inflammatory skin conditions such as eczema and psoriasis, says Dr. Kanchanapoomi Levin. The most common type, narrow band phototherapy, helps reduce itchiness and inflammation by exposing your skin to an increasing amount of a certain wavelength of UV radiation, per the NEA. An impressive 70% of people with eczema get better after receiving this treatment.

If youve tried a handful of home remedies and your persistent itch remains, an underlying condition such as diabetes, kidney or liver disease, infections including Hepatitis B or C, HIV, thyroid problems, or complications of pregnancy, among other issues could be to blame, says Dr. Kanchanapoomi Levin. Its true that day-to-day itch triggers including dry skin and bug bites are *far* more common, but youre best off visiting your doctor or dermatologist to confirm proper treatment.

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More here:
12 Itchy Skin Treatments That Work, According to Dermatologists - Prevention.com

It all started with a Google Doc, which outlined the products she uses to keep her skin clear. Rio now writes about beauty products for us full-time. Shes not a professional, shes just crazy.

Photo: Courtesy of the vendors

Its wild to think that just as recently as three years ago, COSRX the hugely popular Seoul-based brand now sold in Urban Outfitters, Ulta, and Rickys was known only by U.S.based skin-care sleuths (the folks like me who lurked around the r/Asian beauty subreddits, YouTube, and blogs like Fiddy Shades of Snail). Nowadays, it would be difficult to find an Instagram shelfie that didnt feature one of COSRXs clean, medicinal-looking bottles. Even the most entry level of skin-care lovers have at least heard of the brands game-changing cabinet staple: the Pimple Patch, which sucks up excess oil in the skin, flattening your zit significantly over night.

It doesnt surprise me in the least that COSRX has had such a quick rise to fame. Its products are cheap (most are under $20), and more importantly, their straight-to-the point formulas really, really work. I have incredibly reactive, acne- and eczema-prone skin, and not once has a COSRX product broken me out or triggered an eczema flare up. Since I am such a COSRX nut, and can confidently say Ive relentlessly tested every single one of its (ever-widening) array of products, I decided to compile a list of my favorites all of which are worth owning, if you dont already.

COSRX Hydrium Triple Hyaluronic Moisture Ampoule

A relatively new launch from COSRX is this moisturizing hyaluronic acid serum. Its basically a winter soldier in a bottle, combining skin-conditioning glycerin and three different types of hyaluronic acids to deeply hydrate. This also sinks into skin immediately, unlike similar serums like The Ordinarys, which tends to leave an unappealing sticky, wet feeling. If youre struggling with wintertime-related chapped skin, or are just in the market for an affordable and seriously effective hyaluronic acid serum, this is a great choice.

COSRX Ultimate Nourishing Rice Overnight Spa Mask

This suitable-for-just-about-every-skin-type cream is packed with niacinamide, one of my favorite ingredients for healing and brightening, as well as with rice extract, which conditions. My dry, acne-prone skin adores this moisturizer (I put it on as the last step in my routine before bed), but I have pals with much oilier complexions who also adore it and say that it doesnt make them feel greasy or clogged up. If COSRX Hyaluronic Acid Serum is too thick for you, this is a great, lighter-weight (yet still moisturizing) alternative.

COSRX Advanced Snail 92 All In One Cream

You may have heard of COSRX cult-favorite snail mucin essence (more on that later), but have you heard about the cream version?I dont use this product as a night cream personally, I find it a touch too sticky to wear all over my face, though if you dont mind the texture, it does work wonders for healing any blemishes or otherwise damaged skin (like wind-swept cheeks!). Instead, per the advice of my skin-care guru Fiddy Snails, I use this daily under my eyes as an intensely nourishing, smoothing, and replenishing eye cream. Its thick without being pore-clogging, and has helped so much with my fine lines (it has also helped me avoid any concealer creasing whatsoever this winter). Plus, you get a giant jar for a third of the price of a standard Sephora eye cream and, frankly, it works better than any fancy eye cream Ive ever used (including my old Banana Brightening Cream from Ole Henriksen).

COSRX Triple C Lightning Liquid

Popular vitamin C serums on the market, like Glossiers Superglow or Klairs Freshly Juiced vitamin C serum, contain a concentration of around 510 percent vitamin C. COSRX vitamin C serum, however, contains a whopping 20.5 percent higher than even the extremists at Drunk Elephant, whose serum contains only 15 percent vitamin C. The only thing to say about this product is that it just really, really works after a couple weeks of consistent use, you will notice fading of dark spots and an overall brightness in your complexion. If you like Drunk Elephants Vita C, you must try this for half the price.

COSRX AHA 7 Whitehead Power Liquid

COSRX BHA Blackhead Liquid

Put simply: These exfoliants will deeply scrub your skin, leaving a brighter, baby smooth complexion behind. The AHA White Head Power Liquid formula below is made up of glycolic acid and niacinamide, which means its great for tackling on-the-surface issues like dullness, uneven skin tone, or hyperpigmentation. And the BHA Blackhead Power Liquid formula is great for anyone struggling with inflammatory or acne issues (it uses Betaine Salicylate, an exfoliant that penetrates deeper into the skin to break down sebum, as well as White Willow Bark, which can help decrease redness and inflammation). Use this exfoliant right after washing your face, wait as long as you can (20 minutes is recommended), and then proceed with the next step in your skin-care routine. Lot of exfoliants on the market are a blend of AHA and BHA its pretty rare to find exfoliants stripped down this much so you can really exfoliate depending on your concerns. Lots of people like to use both products on different parts of their face: the AHA on areas where they suffer more with pigmentation problems, and BHA where they struggle with acne.

COSRX AC Collection Ultimate Spot Cream

In my opinion, this is one of the most slept-on hits of COSRX. Unlike a lot of spot treatments that are high in benzoyl peroxide and salicylic acid (which can dry out or irritate your skin when used too frequently), this treatment has primarily calming and soothing ingredients: aloe vera, centella, and calamine, all of which help knock redness and general irritation around zits. The second you notice a suspicious bump pop up, this is what you should use: Its totally non-irritating or abrasive, and you will notice the size and swelling of a zit go down straight away.

COSRX Galactomyces Essence

This is a beautiful, effective, and affordable essence to integrate into your routine if youre struggling with acne, texture, dull, or dry skin. Its jam packed with 96 percent galactomyces ferment filtrate, an ingredient that helps restore and brighten the skin. It also has niacinamide, a workhorse ingredient thats incredible for healing and brightening up any dark spots or pigmentation. This can be incorporated into your routine easily niacinamide is an amazing ingredient that can be used alongside exfoliants (AHAs and BHAs), retinol, and vitamin C. With consistent use, youll notice a big improvement on the overall state of your skin. I like to use this daily, after exfoliating.

COSRX Hyaluronic Acid Intensive Cream

One of the best affordable, ultra-rich nighttime creams for winter out there. The two main ingredients of this cream are hippophae rhamnoides water (or water derived from sea-buckthorn berry), which is deeply healing and moisturizing, as well as hyaluronic acid. This is an absolute staple of mine thats saved my skin time and time again from winter dryness and irritation. If you suffer from ultra-parched skin, or if youre looking for an affordable way to battle winter scalies, this is the cream for you.

COSRX Advanced Snail Mucin Power Essence

This blend of hyaluronic acid, snail mucin, and panthenol (an ingredient that has both hydrating and reparative properties) makes for one of the best healing, brightening, and moisturizing essences on the market. This do-it-all essence can combat practically any issues whether it be dullness, dryness, or acne. Even though this is technically an essence, the formula is so thick I like to apply it as the last step before my moisturizer.

COSRX Centella Blemish Cream

This cream is my go-to for healing any kind of scabs or old acne. When you have a scab, it canbe tempting to want to dry it out so that its easier to pick off. This is actually the complete opposite of what you should do: Its been proven that making sure the affected area is as moisturized as possible aids in speeding up the healing time of a pimple. And this cream is exactly what you need to ensure that your annoying little scab gets enough reparative and hydrating treatment to help it move out of your life faster. The formula of this product is made up primarily of ultra-healing centella asiatica leaf water, plus vitamin Erich sunflower oil (another ingredient great for healing compromised skin), as well as Glycerin, a rich skin-conditioning ingredient. I use this anytime I have a weird, picked at scab that I need to get rid of, and it works wonders.

COSRX Acne Pimple Master Patch

In addition to sucking up all that excess oil in your skin and flattening zits out in as fast as one night, as a picker, these little flexible, clear hydrocolloid circles have saved me from myself time and time again. When in doubt (or if youre about to tear into your skin), put a patch on it!

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View original post here:
The 12 COSRX Products Every Skin-Care Fiend Should Have - New York Magazine

LONDON--(BUSINESS WIRE)--Technavio has been monitoring the global eczema therapeutics market and the market is poised to grow by USD 3.60 billion during 2020-2024 at a CAGR of over 9% during the forecast period. Request Free Sample Pages

Read the 152-page research report with TOC on "Eczema Therapeutics Market Analysis Report by Geography (Asia, Europe, North America, and ROW), by Indication (Atopic dermatitis, Contact dermatitis, and Other indication), and Segment Forecasts, 2020-2024".

Factors such as high prevalence of atopic dermatitis and increasing healthcare expenditure are anticipated to boost the growth of the market.

Exposure to skin irritants including soaps or cleaners and allergens such as pet dander, pollen, or peanuts can lead to eczema. It is also caused by infections, dry skin, and stress. Atopic dermatitis is one of the most prevalent forms of eczema which requires multiple visits to dermatologists and numerous medications for treatment. China, India, and Japan are the three major revenue contributors to the market as these regions of Asia constitute a huge patient pool and consequently exhibit a high demand for eczema therapeutics. Thus, the high prevalence of atopic dermatitis is expected to drive market growth during the forecast period.

Buy 1 Technavio report and get the second for 50% off. Buy 2 Technavio reports and get the third for free.

View market snapshot before purchasing

Major Five Eczema Therapeutics Market Companies:

AbbVie Inc.

AbbVie Inc. is headquartered in the US and operates the business under the segment, Pharmaceuticals. The company offers a Janus kinase 1 selective inhibitor, Upadacitinib to various end-users including hospitals and pharmacies.

Alliance Pharma Plc

Alliance Pharma Plc is headquartered in the UK and offers products through the following business units: International Star Brands and Local Brands. The company offers a range of products for different indications such as dry skin, eczema, and ichthyosis.

Bausch Health Companies Inc.

Bausch Health Companies Inc. is headquartered in Canada and operates under various business segments, namely Bausch + Lomb/International, Salix, Diversified Products, and Ortho Dermatologics. The company offers a second-line therapy, Elidel.

Bayer AG

Bayer AG is headquartered in Germany and offers products through the following business segments: Pharmaceuticals, Crop science, Consumer health, and Animal health. The company offers a range of dermatology products for skin care, eczema treatment, and sensitive skin.

Eli Lilly and Co.

Eli Lilly and Co. is headquartered in the US and offers products through the following business segments: Human pharmaceutical products and Animal health products. The company offers a small molecule Janus kinase inhibitor, Olumiant.

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Eczema Therapeutics Indication Outlook (Revenue, USD Million, 2020-2024)

Eczema Therapeutics Regional Outlook (Revenue, USD Million, 2020-2024)

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About Technavio

Technavio is a leading global technology research and advisory company. Their research and analysis focus on emerging market trends and provides actionable insights to help businesses identify market opportunities and develop effective strategies to optimize their market positions.

With over 500 specialized analysts, Technavios report library consists of more than 17,000 reports and counting, covering 800 technologies, spanning across 50 countries. Their client base consists of enterprises of all sizes, including more than 100 Fortune 500 companies. This growing client base relies on Technavios comprehensive coverage, extensive research, and actionable market insights to identify opportunities in existing and potential markets and assess their competitive positions within changing market scenarios.

Originally posted here:
Global Eczema Therapeutics Market 2020-2024| Evolving Opportunities with AbbVie Inc. and Bayer AG | Technavio - Business Wire

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GROWING up, Tasha Harris loved making her own skincare out of tea tree oils and other things her mum had lying around the house - but never in a million years did she think she'd one day be running her own beauty business.

The 29-year-old businesswoman, from Leigh-on-Sea in Essex, first started making her own coffee scrubs out of leftover grinds, coconut oil and salt to treat her eczema in 2012.

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Having experienced first-hand how well it worked on her own dry skin, Tasha began dolling it out to all her friends and family for free - and they were also blown away by the results.

After being inundated with requests for more of the scrub, Tasha - and her partner Lloyd - decided to turn it into a business and only spent 450 to start it up.

In their first three months, Grounded made an impressive 15,000 when they were approached by Dragon's Den producers - this amazing exposure took the business to a whole new level.

Tasha spoke to Fabulous Digital for our#BOSSINGIT seriesdevoted to ordinary women who have launched incredible businesses.

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Describing her struggles with eczema growing up, Tasha said: "I used to get really bad eczema around my neck, my arms, and my mouth - but nothing would get rid of it."

As Tasha's school wouldn't let students carry lip balms or hand creams, she'd have sit and suffer with her itchy skin during lessons.

She added: "My doctors kept giving me steroid creams but it just made it more uncomfortable and horrible."

However, Tasha noticed that her skin would only ever improve when she was on holiday and had her first experience with coffee scrubs at a spa in Bali when she was 22.

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"The only time my eczema would get better is if I went on holiday somewhere really hot with the nice salty sea," she said. "But it was always really, really bad."

Noticing coffee scrubs as an emerging trend abroad (and were already wildly popular in Australia), Tasha and Lloyd tried experimenting with their own at home using his family's leftover coffee grinds - but only ever intended for it to help with her own skin problems.

She recalled: "He went online and started researching ingredients and put in stuff that I'd already used on my skin - like coconut oil.

"But he also put in things that didn't feel nice, like olive oil which made it all greasy and horrible."

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Whereas prescribed steroid creams often result in peeling, Tasha claims the scrubs nourish skin and leaves it soft and supple.

She explained: "With the coffee scrub, youve got coffee which helps blood circulation, then youve got salt which is anti-bacterial and then coconut oil which softens the skin and helps heal it.

"It also makes it really smooth so youre not itching it all the time."

After noticing a drastic difference in her own skin, Tasha - who was working at a local bank branch at the time - began giving her colleagues free samples of the scrub.

But it was only when she kept being asked for top ups that they started to take it more seriously.

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Describing how she initially saw it as a hobby, Tasha said: "I was just going with the flow really but when people keep asking you for the stuff, you realise how good it is."

After being inundated with glowing customer reviews, the couple decided to take the plunge.

"We started the company with nothing," Tasha recalled. "We paid for the logo which was 350 and then we bought a box of bags for about 100. Everything else we needed to make the scrubs we already had in our kitchen."

In order to kickstart the business, Tasha created an Etsy shop where customers could shop the 13 coffee scrubs - which were still being made from her and Lloyd's kitchen table using leftover grinds.

Now that the company have their own in-house manufacturers, it costs them 1.50 to make a 200g pouch of coffee scrub - but when they were starting still out, it was originally 2.10.

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On top of this, they also started travelling to shows across the country to promote Grounded and made themselves stand out from other brands by decorating their stalls with inflatable palm trees and vintage furniture borrowed from Lloyd's mum's store.

Ahead of each show, Tasha explained: "We'd spend 2,000 of our own savings on creating the product and then we'd put that straight back into the business.

"We made hundreds of coffee scrubs, put a bowl in the middle and got customers to test it out on their hands. We made 15,000 for three shows."

Unsurprisingly, the tropical (and wildly popular) stall caught the attention of a Dragon's Den producer who invited them in to interview for the programme - but their first reaction was to assume it was all just a big practical joke.

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"We were just getting the stand ready with palm trees and stuff and then he went over to Lloyd and gave him his email," Tasha said. "They asked if we wanted to interview for the show next week but we thought it was just a lie though."

In 2015, the couple appeared on the hit BBC show and secured 30,000 funding from Sarah Willingham in exchange for a 15 per cent stake in the company.

After filming wrapped, Tasha got in touch with major retailers to get Grounded scrubs into stores - and three months before the show aired, Boots said they wanted to fast track the scrubs to hit shelves as soon as possible.

Delighted by the news, Tasha reached out to Sarah to get the funding and start making the 100k worth of product Boots has ordered - but was merely told "she couldn't do anything at all until after the show had aired".

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In order to supply the enormous Boots order, the couple needed 20,000 and fast - luckily, they were able to borrow the money from Lloyd's mum's business.

As well securing the Boots deal, Tasha got the Grounded website up and running and the night the Dragon's Den episode aired in April 2016, they has 85,000 visitors to the site.

And it would be selling short to say the scrubs were an overnight success - in that first month, Grounded made a whopping 50,000 and Tasha and Lloyd were working all hours of the day to keep up with the orders on the website.

After being overwhelmed with orders, Tasha added: "We had to turn off our website and redirect it all to Boots because we didn't have any product left."

Over three years on, Grounded is now the UK's leading coffee-based beauty brands and they now count EastEnders' Maisie Smith among their thousands of fans.

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Naturally, the packagaing has also had an Instagram-friendly rebrand.

Tasha said: "When we started off, everything was quite dark and dingy. In Dragons Den, everything was brown for grounded coffee.

"But we wanted to make it a bit brighter and fun so we introduced some colours and developed a new logo."

The company - which employs 30 people - now have their own manufacturers to make their products on site which cost hundreds of thousands of pounds - but it's worth it for Tasha knowing that all the scrubs are up to scratch.

Trying to keep up with beauty trends has been another challenge for Tasha - and the brand has brought out CBD face oils, charcoal toothpaste and anti-ageing eye creams over the years.

Although the brand now boasts 20 products across their hair, body and skincare ranges, it's their original coconut-scented scrub that continues to be a fan favourite.

In the past seven years, the brand has sold over half a million units of their best-selling coconut scrub - and now that microbeads are firmly out of fashion, Grounded shows no signs of slowing down any time soon.

Tasha's top tips for aspiring businesswomen

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For more inspiring Bossing It stories, Fabulous Digital spoke to the founder of Holly's Lollies who set up her 300k business from her kitchen table.

And we also spoke to Florence Ledwith - who moved back into her childhood bedroom to set up her dream shoe business and now makes 350k a year.

Plus Caroline Sims was too ashamed to let her boyfriend see her problem skin without make-up - now her skincare supplements are set to make 4m.

Go here to read the rest:
I started my coffee body scrub business with 450 now its turned over 15m and Maisie Smith is a fan - The Sun

It's an uncomfortable sensationa sudden tickle or prickle that begs for you to scratch. And sometimes, itchy skin is accompanied by rashes or patches that you'd rather not show the world. We spoke to three board-certified dermatologists about possible sources of itchy skinand what exactly you can and should do about it.

Related: How to Prevent Eczema Flares During the Winter

All of the professionals we interviewed agree: Dry skin is the leading cause of itchiness. Avoid this, particularly during winter or in areas with low humidity, by keeping your skin hydrated. "Avoid long, hot baths or showers," advises Dr. Dina Strachan, MD, Director of Aglow Dermatology in New York City. "Use a moisturizing cleanser. Apply moisturizer after bathing." Another dermatologist, Margaret E. Parsons, MD, FAAD, Dermatology Consultants of Sacramento, specifically recommends Eucerin, Cetaphil, and CeraVe, and for more sensitive skin, Vanicream and non-irritating emollients such as petroleum jelly (Vaseline), Aquaphor, and even coconut oil and shea butter. "There are some over-the-counter products that can relieve itch, including products with pramoxine or menthol," adds Bruce A. Brod, MD, FAAD Clinical Professor of Dermatology at the University of Pennsylvania, Perelman School of Medicine.

There's atopic dermatitis, also known as eczema (dry, rashy skin), seborrheic dermatitis (patches mainly on the scalp and possibly ears and eyebrows), and contact dermatitis (triggered, as the name implies, when the skin comes in contact with an irritant or allergen, which can be anything from skin and haircare products to fabric to poison ivy). "I always review if there are any new clothes, soaps, hair products, foods, travel, or anything else new in someone's life when they have a skin issue," Dr. Parsons, who is also the Associate Clinical Professor at UC Davis, Department of Dermatology, tells us. "Often people say, 'It's all the same,' and we have to remember we can acquire sensitivities or allergies, or a product may have had ingredients changed."

She adds that it can take two months for some itches to calm down because of skin's "memory cells" and cautions people with sensitive skin to avoid fabric softeners and dryer sheets and reach for perfume- and dye-free laundry products. In clothing, opt for natural, non-irritating fibers: cotton, silk, linen, wool, and bamboo. To temporarily treat these issues, Dr. Parsons says you can take antihistamines, such as the more sedating diphenhydramine (Benadryl) or the prescription hydroxyzine, cetirizine (Zyrtec), loratadine (Claritin), fexofenadine (Allegra), or levocetirizine (Xyzal). "For more notable eczema, topical corticosteroid creams or ointments are often prescribed," she adds. "There are also some non-steroid prescription topicals for those with persistent skin concerns."

It's an unpleasant thought, but there's a chance your crawling skin is due to a crawling or flying creature. You're probably all too familiar with mosquito and spider bites from your youth or from time spent in the garden. Insect-related or otherwise, pay close attention to any sudden, severe itch and hives. "If someone has any trouble breathing or lip swelling, that of course would be of great concern and needs to be promptly evaluated, possibly at the emergency room if severe," Dr. Parsons advises.

Though not as likely as the aforementioned causes, itchy skin could also be a sign of an internal condition such as diabetes, thyroid disease, anemia, kidney or liver disease, or even cancer, say our pros. "With these medical conditions, there is usually other things going on with general health such as fatigue," Dr. Parsons explains. That's why anyone experiencing an itch that just won't quit should make an appointment with a board-certified dermatologist. "If the itch is due to a skin condition, then treating the underlying skin condition can help," Dr. Brod adds. "Itch is a complex issue and should be carefully evaluated by a medical professional."

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Common Itching Causes and Fixes, According to Dermatologists - Yahoo Lifestyle

WINNIPEG, Manitoba, Dec. 16, 2019 (GLOBE NEWSWIRE) -- Kane Biotech Inc. (TSX-V:KNE) (the Corporation or Kane Biotech), a biotechnology company engaged in the research, development and commercialization of technologies and products that prevent and remove microbial biofilms, today announced that it has launched a consumer product test to evaluate the efficacy of its new shampoo on dermatitis and dandruff.

Recent research has indicated that the persistence of microbial biofilm may be linked with aggravating the symptoms associated with atopic dermatitis, seborrheic dermatitis (also known as eczema) and dandruff. Kane Biotechs shampoo consists of coactiv+TM, a patented anti-biofilm formulation, and contains ingredients approved as safe for human use.

Kane Biotech will ship 300 samples to registered adult participants in Ontario and Manitoba with moderate-to-severe atopic dermatitis, seborrheic dermatitis and/or severe dandruff. Individuals interested in participating in the consumer product test may register at https://kanebiotech.com/shampoo-consumer-test/. In addition, the Corporation plans to promote the consumer test with a Facebook advertising campaign in January 2020. Shipping of test samples is expected to commence in February 2020.

In the U.S., the anti-dandruff shampoo market alone is estimated at $3 billion per year, while some 31.6 million individuals have some form of eczema, stated Marc Edwards, CEO of Kane Biotech. We have anecdotal evidence that indicates our shampoo offers individuals suffering from these conditions an effective treatment option without requiring any harsh ingredients such as coal tar, ketoconazole or selenium sulfide. We are looking forward to the feedback we receive from this expanded group of consumers.

I highly encourage those looking for a solution to dry, flaking and itching scalps to participate in Kane Biotechs consumer product test, said David Kemp, a long-time Kane Biotech investor. As sufferers of these conditions, my family and I tried this shampoo, and nothing has worked better. Im delighted Kane is moving forward with this trial both as an investor and a consumer.

I want to thank the entire Kane team for bringing this project together. We already have a number of very exciting projects in both Animal Health (Oral Care, Skin Care and Supplements) and Human Health (Chronic Wound Care) on the go that require our attention, but they have once again demonstrated their nimbleness by taking on this additional program, said Mr. Edwards. I love this type of project where we take good science and, in short order, are able to get it into the hands of consumers. The very small investment of capital associated with this consumer testing could yield substantial dividends for Kane in the future.

About Kane Biotech

Kane Biotech is a biotechnology company engaged in the research, development and commercialization of technologies and products that prevent and remove microbial biofilms. The Corporation has a portfolio of biotechnologies, intellectual property (56 patents and patents pending, trade secrets and trademarks) and products developed by the Corporations own biofilm research expertise and acquired from leading research institutions. StrixNBTM, DispersinB, Aledex, bluestemTM, AloSeraTM, coactiv+TM and Kane are trademarks of Kane Biotech Inc. The Corporation is listed on the TSX Venture Exchange under the symbol "KNE".

For more information, please visitwww.kanebiotech.com, or contact:

Neither TSX Venture Exchange nor its Regulation Services Provider (as that term is defined in policies of the TSX Venture Exchange) accepts responsibility for the adequacy or accuracy of this release.

Caution Regarding Forward-Looking Information

This press release contains certain statements regarding Kane Biotech Inc. that constitute forward-looking information under applicable securities law. These statements reflect managements current beliefs and are based on information currently available to management. Certain material factors or assumptions are applied in making forward-looking statements, and actual results may differ materially from those expressed or implied in such statements. These risks and uncertainties include, but are not limited to, risks relating to the Companys: (a) financial condition, including lack of significant revenues to date and reliance on equity and other financing; (b) business, including its early stage of development, government regulation, market acceptance for its products, rapid technological change and dependence on key personnel; (c) intellectual property including the ability of the Company to protect its intellectual property and dependence on its strategic partners; and (d) capital structure, including its lack of dividends on its common shares, volatility of the market price of its common shares and public company costs. Further information about these and other risks and uncertainties can be found in the disclosure documents filed by the Company with applicable securities regulatory authorities, available at http://www.sedar.com. The Company cautions that the foregoing list of factors that may affect future results is not exhaustive.

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Kane Biotech Launches Consumer Product Test for an Innovative Shampoo Containing its Patented Anti-Biofilm Technology - GlobeNewswire

BALLERUP, Denmark--(BUSINESS WIRE)--LEO Pharma A/S, a global leader in medical dermatology, today announced that tralokinumab an investigational, fully human monoclonal antibody that specifically neutralizes the interleukin-13 (IL-13) cytokine met all primary and secondary endpoints in its three pivotal Phase 3 studies (ECZTRA 1-3) for the treatment of moderate-to-severe atopic dermatitis (AD) in adults. During the studies, the overall adverse event rate was comparable between tralokinumab and placebo.

IL-13 is a key driver of the type 2 inflammation that plays a major role in AD,1 which is the most common inflammatory skin disease in the developed world,2 affecting up to five percent of adults across the United States, Canada, Europe and Japan.3 AD can have a significant, negative impact on patients well-being, primarily due to distressing itch, sleep deprivation and social stigmatization due to visible lesions.4

In its moderate-to-severe form, AD can cause unbearable recurring symptoms for patients, said Dr Kim Kjoeller, Executive Vice President, Global Research & Development, LEO Pharma. Despite recent treatment advances, we consistently hear from healthcare professionals around the world that additional treatment options are needed to address the different signs and symptoms for each patient. We are encouraged by these study results, which show that tralokinumab could be an efficacious and well-tolerated long-term treatment solution for patients living with this debilitating chronic skin disease.

ECZTRA 1 and ECZTRA 2 (ECZema TRAlokinumab studies no. 1 and 2), are randomized, double-blind, placebo-controlled, multinational, 52-week studies, which included 802 and 794 adult patients respectively, to evaluate the efficacy and safety of tralokinumab as monotherapy in adults with moderate-to-severe AD who are candidates for systemic therapy. ECZTRA 3 is a randomized, double-blind, placebo-controlled, multinational 32-week study, which included 380 adult patients, to evaluate the efficacy and safety of tralokinumab in combination with topical corticosteroids (TCS) in patients with moderate-to-severe AD who are candidates for systemic therapy.

The primary endpoints in the three studies were an Investigator Global Assessment (IGA) score of clear (0) or almost clear (1) skin at week 16 and at least a 75 percent or greater change from baseline in their Eczema Area and Severity Index (EASI) score at week 16. A change from baseline to week 16 in SCORing of Atopic Dermatitis (SCORAD), Pruritus Numeric Rating Scale (NRS) of at least 4, and Dermatology Life Quality Index (DLQI) were secondary endpoints.

LEO Pharma is planning to submit marketing authorization applications for tralokinumab for the treatment of adult patients with moderate-to-severe AD to regulatory agencies in 2020 and plans to submit the detailed results of these studies for presentation at scientific congresses and publication in peer-reviewed medical journals in 2020 as well. Further information about trials with tralokinumab can be accessed at https://clinicaltrials.gov.

#ENDS#

NOTES TO EDITORS

About atopic dermatitisAtopic dermatitis (AD) is a chronic, relapsing skin disease, characterized by severe itch, dry skin, persistent immune-mediated inflammation, and skin barrier defects.5 AD is a result of skin barrier dysfunction and immune dysregulation, leading to chronic inflammation.6 Type-2 cytokines, such as IL-13 and IL-4, play a central role in the key aspects of AD pathophysiology.7 Due to the immune dysregulation, IL-13 is overexpressed in lesional and non-lesional skin.8,9

About tralokinumabTralokinumab is an investigational agent under clinical development, and its safety and efficacy have not been evaluated by any regulatory authority. Tralokinumab is a fully human, immunoglobulin (Ig)G4 monoclonal antibody (mAb) that works by neutralizing the IL-13 cytokine. IL-13 plays a key role in the pathophysiology of AD.10 By specifically binding to the IL-13 cytokine, tralokinumab prevents its interaction with the receptor and the subsequent downstream IL-13 signalling.11

About LEO PharmaLEO Pharma helps people achieve healthy skin. The company is a leader in medical dermatology with a robust R&D pipeline, a wide range of therapies and a pioneering spirit. Founded in 1908 and owned by the LEO Foundation, LEO Pharma has devoted decades of research and development to advance the science of dermatology, setting new standards of care for people with skin conditions. LEO Pharma is headquartered in Denmark with a global team of 6,000 people, serving 76 million patients in 130 countries. In 2018, the company generated net sales of DKK 10,410 million. For more information about LEO Pharma, visit http://www.leo-pharma.com.

References1 Bieber T. Interleukin-13: Targeting an underestimated cytokine in atopic dermatitis. Allergy 2019; doi:10.111/all.13954.2 Weidinger S et al. Atopic Dermatitis. Nat Rev Dis Primers 2018; 4(1):1.3 Barbarot S et al. Epidemiology of atopic dermatitis in adults: Results from an international survey. Allergy 2018;73:1284-1293.4 Weidinger S, Novak N. Atopic dermatitis. The Lancet. 2016; 387:1109-22.5 Weidinger S, Novak N. Atopic dermatitis. The Lancet. 2016; 387:1109-22.6 Boguniewicz M and Leung DY. Atopic dermatitis: a disease of altered skin barrier and immune dysregulation. Immunol Rev 2011 Jul;242(1):233-46. 7 Bieber T. Interleukin-13: Targeting an underestimated cytokine in atopic dermatitis. Allergy 2019; doi:10.111/all.13954.8 Tsoi LC et al. Atopic dermatitis is an IL-13 dominant disease with greater molecular heterogeneity compared to psoriasis. J Invest Dermatol 2019 (Accepted Manuscript) https://doi.org/10.1016/j.jid.2018.12.018. 9 Tazawa T et al. Relative importance of IL-4 and IL-13 in lesional skin of atopic dermatitis. Arch Dermatol Res. 2004;295:459-464.10 Brandt, E.B., Sivaprasad, U. Th2 Cytokines and Atopic Dermatitis. J Clin Cell Immunol. 2011; 2(3): 1-25. doi:10.4172/2155-9899.1000110.11 Popovic B et al. Structural characterisation reveals mechanism of IL-13-neutralising monoclonal antibody tralokinumab as inhibition of binding to IL-13R1 and IL-13R2. J Mol Biol. 2017;429:208-219.

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LEO Pharma announces positive top-line results for tralokinumab from three Phase 3 studies in adult patients with moderate-to-severe AD - Business...

Dr. Tara Zandvliet didnt intend to be a Voice of the Year.

She had a quiet practice in South Park, where many vaccine-skeptical parents found her by word of mouth. If they could show her a family history of autoimmune disorder even psoriasis and eczema qualified she would write their child a medical exemption from vaccination.

By her estimation, Zandvliet has written roughly 1,000 exemptions. At $180 per exemption, she made nearly $200,000 in her small corner of the market. But the general public had no idea Zandvliet was Southern Californias vaccine exemption doctor of choice.

Then in March, her business attracted more attention than she ever wanted. A Voice of San Diego investigation revealed that Zandvliet had written nearly a third of all vaccine exemptions in San Diego Unified School District.

Legislators like Sen. Richard Pan and Assemblywoman Lorena Gonzalez swiftly reacted to crack down on what Pan called unscrupulous physicians looking to make a buck who were gravely endangering the community.

Pan and Gonzalez wanted public health officials to oversee vaccine exemptions, so that doctors like Zandvliet would no longer be able to write them for reasons that fall outside the generally recognized standard of care.

The anti-vaxx movement quickly rallied, staging rowdy protests in Sacramento.

Pan got shoved on the street by a man live-streaming the attack. A woman tossed a menstrual cup full of blood onto the floor of the state Senate. Gov. Newsom hesitated, suggesting he might not sign the new legislation.

After months of debate that echoed out across the entire state, Pan and Gonzalez were successful. They passed a bill that will make it easier for state officials to crack down on doctors writing bogus exemptions. Zandvliet has also been charged with gross negligence by the state Medical Board.

This is part of our Voice of the Year package, highlighting the people who played a major role in shaping civic discussion in 2019.

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Voice of the Year: Dr. Tara Zandvliet - Voice of San Diego

Dr Joel Akande

Let me clarify a common misconception immediately now. To medical doctors, eczema is a distinct skin illness. This is different from what the general public considers as eczema. In the perception of the public, eczema covers practically all common skin diseases.

This should not be so. On the other hand, eczema and dermatitis are frequently used as if they mean the same thing. First, dermatosis. Dermatosis means any skin disease. Dermatitis means inflammation of the skin as measured by swelling, heat generation, pain and change in colour.

What is Eczema? Coming from the Greek word, ekzein, eczema means to boil out as a result of the evolution of the skin changes under eczema.

Eczema, therefore, has the following characteristics: rashes (macules for example), redness, crusting of skin, oedema or swelling, thickening of the skin due to repeated and frequent rubbing of or scratching of the skin and finally changes in the skin colour.

We should not forget that the disposition of the individual to develop eczema is equally important. The changes in colour and thickening occur at a later development or weeks after the initial changes as mentioned above. The first is acute and the second is called chronic eczema.

Types of Eczema: I will only mention here that eczema can be classified as endogenous (internal) or exogenous (internal). Of the internal, atopic eczema is perhaps the commonest. I will discuss a brief of this condition later as its seen in a lot of ways in children.

Seborrhoeic dermatitis seen frequently on the scalp of children and women is also common. Other conditions are discoid eczema, pompholyx and peeling skin syndrome. For exogenous eczema, hand dermatitis, irritant dermatitis, photo dermatitis, infective eczema, allergic contact dermatitis, exfoliative and perioral dermatitis are common examples.

I will now discuss a few of the common forms of eczema amongst our population.

Atopic eczema (dermatitis): This is a common illness and is said to account for about 20 per cent of skin disorders seen at skin clinics.

Children fed on cows milk rather than on breast milk are more likely to develop atopic eczema. Children fed on mixed breast and cows milk are also at risk.

Causes of atopic eczema: The human body reacts to intolerable agent internally but later shows up in the skin. Some diseases such as deficiency in some vitamins (biotin), cystic fibrosis may lead to eczema. Atopic eczema may also develop due to infections such as staphylococcus infection.

How does atopic eczema present? Children, infants and adults are affected. And it can show up as early as 2 weeks of life.

There are patches in both sides of the body especially on the joints of elbows, behind the knees, cheeks and forehead. Widespread dry skin involvement may occur. Itching and scratching, dryness of the skin, crusting are present.

The skin become thickened and may become infected. The face may be affected too. By age of 2-3 years, the eczema may or may not disappear only to reappear later in childhood and adulthood.

Treatment: Information and knowledge is power. Its important that adult victims and parents of children should get as much knowledge and information about the eczema as much as possible.

Atopic eczema requires intervention of specialist dermatologist. The medical doctor will endeavor to contain troublesome itching as well as ensuring the dry crusted skin remain moist.

Doctors are also likely to pay attention to curtailing inflammation and preventing occurrence of underlying causes.

Other common and important eczematous forms are contact dermatitis.

This indicates that there are agents that the sufferers have been in contact with that are ultimately responsible for the eczema now being suffered. Seborrhoeic dermatitis is common and will require a physicians attention.

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Revisit on skin diseases: eczema (3) - The Nation Newspaper