Category Archives: DNA

Scientists around the world are racing to record the genetic blueprints of every known species on the planet. The effort comes as the United Nationswarns that an estimated one million plant and animal species are at risk of becoming extinct within the coming decades.

"This is absolutely urgent," researcher Joanna Harley told CBS News correspondent Roxana Saberi. "It's really important to protect species on this planet. They share with us and they keep us going and the more we erode away at the world, the less there will be."

Around 5,000 scientists across the globe are part of the Earth BioGenome Project. Over the next decade, teams will digitize DNA of the 1.8 million named plant, animal, fungi and single-celled eukaryote species on the planet. By the end of 2022, the scientists plan on sequencing 3,000 genomes.

By DNA sequencing life on Earth, the researchers have goals of benefitting human welfare, protecting biodiversity and better understanding ecosystems.

"Everything's interconnected," Mark Blaxter, who leads a group working under the Earth BioGenome Project, told Saberi. "We need the services that these plants and animals and fungi give us...so by understanding how they do it, we can help humans as well."

So far, researchers in Britain have recorded the genetic blueprints of nearly 400 of the country's 70,000 known species.

The lengthy process begins with researchers like Harley who help search for species. The collected specimens are then sent for sorting before they're shipped off to sequencing labs. The data is then shared online.

"We'll be able to look at a species and work out whether it's endangered or not, and we'll know what to do to keep it going," Blaxter said.

The scientists added that decoding DNA won't save endangered plants and animals alone, but that it can be beneficial as more species are on the track of extinction.

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Tori B. Powell is a breaking news reporter at CBS News. Reach her at tori.powell@viacomcbs.com

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Scientists race to digitize DNA of every known species on the planet - CBS News

Experiments from the UNC School of Medicine lab of Nobel Prize-winning scientist Aziz Sancar, MD, PhD, show how a common molecular tool for DNA labeling also has anticancer properties worthy of further investigation, especially for brain cancers.

CHAPEL HILL, NC Scientists at the UNC School of Medicine have made the surprising discovery that a molecule called EdU, which is commonly used in laboratory experiments to label DNA, is in fact recognized by human cells as DNA damage, triggering a runaway process of DNA repair that is eventually fatal to affected cells, including cancer cells.

The discovery, published in the Proceedings of the National Academy of Sciences, points to the possibility of using EdU as the basis for a cancer treatment, given its toxicity and its selectivity for cells that divide fast.

The unexpected properties of EdU suggest it would be worthwhile to conduct further studies of its potential, particularly against brain cancers, said study senior author Aziz Sancar, MD, PhD, the Sarah Graham Kenan Professor of Biochemistry and Biophysics at the UNC School of Medicine and member of the UNC Lineberger Comprehensive Cancer Center. We want to stress that this is a basic but important scientific discovery. The scientific community has much work ahead to figure out if EdU could actually become a weapon against cancer.

EdU (5-ethynyl-2-deoxyuridine) is essentially a popular scientific tool first synthesized in 2008 as an analog, or chemical mimic, of the DNA building block thymidine which represents the letter T in the DNA code of adenine (A), cytosine (C), guanine (G) and thymine (T). Scientists add EdU to cells in lab experiments to replace the thymidine in DNA. Unlike other thymidine analogs, it has a convenient chemical handle to which fluorescent probe molecules will bond tightly. It thus can be used relatively easily and efficiently to label and track DNA, for example in studies of the DNA replication process during cell division.

Since 2008, scientists have used EdU as a tool in this way, as published in thousands of studies. Sancar, who won the 2015 Nobel Prize for Chemistry for his seminal work on DNA repair, is one such scientist. When his lab began using EdU, his team unexpectedly observed that EdU-labeled DNA triggered a DNA repair response even when it wasnt exposed to DNA-damaging agents, such as ultraviolet light.

That was quite a shock, Sancar said. So we decided to explore it further.

Following up on the strange observation, the team discovered that EdU, for reasons that are still unclear, alters DNA in a way that provokes a repair response called nucleotide excision repair. This process involves the removal of a short stretch of damaged DNA and re-synthesis of a replacement strand. This is the mechanism that repairs most damage from ultraviolet light, cigarette smoke, and DNA-altering chemo drugs. The researchers mapped EdU-induced excision repair at high resolution and found that it occurs across the genome, and it apparently occurs again and again, since each new repair strand includes EdU and thus provokes the repair response anew.

It had been known that EdU is moderately toxic to cells, though the mechanism of its toxicity had been a mystery. The teams findings strongly suggest that EdU kills cells by inducing a runaway process of futile excision repair, which ultimately leads the cell to terminate itself through a programmed cell-death process called apoptosis.

That discovery was interesting in its own right, Sancar said, because it suggested that researchers using EdU to label DNA need to take into account its triggering of runaway excision repair.

As we speak, hundreds and maybe thousands of researchers use EdU to study DNA replication and cell proliferation in lab experiments without knowing that human cells detect it as DNA damage, Sancar said.

Sancar and colleagues also realized that EdUs properties might make it the basis for an effective brain cancer drug because EdU becomes incorporated into DNA only in cells that are actively dividing, whereas, in the brain, most healthy cells are non-dividing. Thus, in principle, EdU could kill fast-dividing cancerous brain cells while sparing non-dividing, healthy brain cells.

Sancar and his team hope to pursue follow-up collaborations with other researchers to investigate EdUs properties as an anticancer agent.

Prior studies have already found evidence that EdU kills cancer cells, including brain cancer cells, but strangely, no one has ever followed up on those results, Sancar said.

Nucleotide excision repair removes thymidine analog 5-ethynyl-2-deoxyuridine from the mammalian genome was co-authored by Li Wang, Xuemei Cao, Yanyan Yang, Cansu Kose, Hiroaki Kawara, Laura Lindsey-Boltz, Christopher Selby, and Aziz Sancar. Funding was provided by the National Institutes of Health (GM118102, ES02755).

Media contact: Mark Derewicz, UNC School of Medicine, 919-923-0959

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Scientists Discover Surprise Anticancer Properties of Common Lab Molecule | Newsroom - UNC Health and UNC School of Medicine

If you're looking for a multi-bagger, there's a few things to keep an eye out for. One common approach is to try and find a company with returns on capital employed (ROCE) that are increasing, in conjunction with a growing amount of capital employed. Ultimately, this demonstrates that it's a business that is reinvesting profits at increasing rates of return. With that in mind, the ROCE of Denbury (NYSE:DEN) looks great, so lets see what the trend can tell us.

If you haven't worked with ROCE before, it measures the 'return' (pre-tax profit) a company generates from capital employed in its business. To calculate this metric for Denbury, this is the formula:

Return on Capital Employed = Earnings Before Interest and Tax (EBIT) (Total Assets - Current Liabilities)

0.24 = US$378m (US$2.1b - US$539m) (Based on the trailing twelve months to June 2022).

So, Denbury has an ROCE of 24%. That's a fantastic return and not only that, it outpaces the average of 16% earned by companies in a similar industry.

Check out our latest analysis for Denbury

roce

In the above chart we have measured Denbury's prior ROCE against its prior performance, but the future is arguably more important. If you're interested, you can view the analysts predictions in our free report on analyst forecasts for the company.

Denbury has not disappointed in regards to ROCE growth. We found that the returns on capital employed over the last five years have risen by 450%. That's a very favorable trend because this means that the company is earning more per dollar of capital that's being employed. Interestingly, the business may be becoming more efficient because it's applying 61% less capital than it was five years ago. If this trend continues, the business might be getting more efficient but it's shrinking in terms of total assets.

On a side note, we noticed that the improvement in ROCE appears to be partly fueled by an increase in current liabilities. The current liabilities has increased to 25% of total assets, so the business is now more funded by the likes of its suppliers or short-term creditors. Keep an eye out for future increases because when the ratio of current liabilities to total assets gets particularly high, this can introduce some new risks for the business.

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In the end, Denbury has proven it's capital allocation skills are good with those higher returns from less amount of capital. And investors seem to expect more of this going forward, since the stock has rewarded shareholders with a 29% return over the last year. So given the stock has proven it has promising trends, it's worth researching the company further to see if these trends are likely to persist.

Like most companies, Denbury does come with some risks, and we've found 1 warning sign that you should be aware of.

If you'd like to see other companies earning high returns, check out our free list of companies earning high returns with solid balance sheets here.

Have feedback on this article? Concerned about the content? Get in touch with us directly. Alternatively, email editorial-team (at) simplywallst.com.

This article by Simply Wall St is general in nature. We provide commentary based on historical data and analyst forecasts only using an unbiased methodology and our articles are not intended to be financial advice. It does not constitute a recommendation to buy or sell any stock, and does not take account of your objectives, or your financial situation. We aim to bring you long-term focused analysis driven by fundamental data. Note that our analysis may not factor in the latest price-sensitive company announcements or qualitative material. Simply Wall St has no position in any stocks mentioned.

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We Think Denbury (NYSE:DEN) Might Have The DNA Of A Multi-Bagger - Yahoo Finance

STUNNED BY veteran leader Ghulam Nabi Azads resignation and his attack on Rahul Gandhi, the Congress initially questioned the timing of his decision, and then launched a scathing counter-attack, accusing him of being in cahoots with the BJP. Several Congress leaders, including its two chief ministers, Ashok Gehlot and Bhupesh Baghel, attacked Azad.

It is most unfortunate and most regrettable that this has happened when Congress president Sonia Gandhi, Rahul Gandhi and the entire Congress party organisation across the country is engaged in confronting, combating and fighting the BJP on public issues of price rise, unemployment and polarisation, Jairam Ramesh, AICC general secretary in charge of communication, said at a press conference.

The Congress had earlier scheduled a press conference to be addressed by Ajay Maken, to target the AAP government in Delhi on the liquor policy. But it cancelled this, and a short statement was read out by Maken and Ramesh on Azads resignation instead.

The entire Congress party organisation has been involved in preparing for the Mehangai Par Hallo Bol rally in New Delhi on September 4 which would be addressed by Rahul Gandhi. Twenty-two press conferences have been scheduled across the country on August 29. The launch of the Bharat Jodo Yatra will take place on September 7 in Kanyakumari; finalisation of that launch is also underway and 32 press conferences have been scheduled across the country to project the message of the Bharat Jodo Yatra, Ramesh said.

So, at a time when every Congressman and every Congresswoman is involved in ensuring that the rally is a success, and wants to be a Bharat yatri and walk along with Rahul Gandhi it is most unfortunate and most regrettable that we have had to read this letter that has been released to the press, Ramesh said.

Launching an all-out attack soon after, Ramesh tweeted: A man who has been treated with the greatest respect by the Congress leadership has betrayed it by his vicious personal attacks which reveal his true character. GNAs DNA has been modi-fied First Modis tears in Parliament, then Padma Vibhushan, then the extension for residence. Yeh sanyog nahi, sahyog hai (Its not a coincidence, its a collaboration).

Ramesh said the contents of Azads resignation letter were not factual and its timing was awful.

The partys media department head, Pawan Khera, linked Azads resignation to the end of his Rajya Sabha tenure. As soon as your Rajya Sabha term got over, you became restless, you cannot stay without a post even for a second. It is a challenging time, everyone is fighting together and the party is being strengthened under Rahul Gandhis leadership, he said, adding that the people who had contributed to weakening the party were now saying that the party has been weakened.

Claiming that every party worker was aware of this betrayal, Khera said his (Azads) remote control is in the hands of Modi. We have seen the love between Narendra Modi and Ghulam Nabi Azad, it was also seen in Parliament. That love has been manifested in this letter, he said.

It is very clear. Perhaps you have joined hands with those people who have scrapped Article 370 in Kashmir. Ho sakta hai kuch aapke unke saat madhur sambandh ho gaye honge (It is possible that you have a warm relationship with them). But I want to tell you one thing. You have written in the letter that it is time to unite the Congress. And in the same letter you are saying there is no need for Bharat jodo. Instead of uniting the Congress, I condemn the step that you have taken to divide the Congress, said senior party leader Digvijaya Singh.

And that at a time when Sonia Gandhi, whose family had given you everything, is abroad for medical treatment. I did not expect this from you. The Congress had given you everything. At such a time of crisis, you should have stood firmly with the Congress, he said.

Gehlot said Rahul would have his own ideas on taking the Congress forward. I am aghast. I am shocked. We have been together for 42 years. The party gave him every opportunity be it Indira Gandhi or Sanjay Gandhi they even went to attend Azads wedding in Srinagar. From there it all started they wanted to promote the young man for the last 42 years, he got all the posts, all the opportunities Union minister, AICC general secretary, chief minister The Congress never hesitated in giving him opportunities, Gehlot said.

Today, his identity in the country is because of the Congress, because of Indira Gandhi, Rajiv Gandhi, P V Narasimha Rao and Sonia Gandhi. I do not think the way he has expressed his sentiment can be called proper Whatever our identity is today is due to the faith the Congress high command had in us. How many people get a chance? No one in the country expected that Azad saab would now write such a letter, he said.

Questioning the timing of the decision, at a time when Sonia is abroad for a medical check-up, Gehlot said: This, I believe, is against human nature, against sensitivity.

Baghel said Azad was constantly trying to harm the party. The party had given him full respect. He was made a cabinet minister and chief minister. His exit will cause no loss to the party, he said.

Leader of the Opposition in Rajya Sabha Mallikarjun Kharge said Azads remarks against Rahul were not in good taste. He enjoyed everything, power and authority, for a long time and is now finding fault, he said.

Link:
Cong's reply: His DNA is modi-fied, remote in Modi hands - The Indian Express

Changing the number of chromosomes an animal has can take millions of generations to happen in nature through the course of evolution and now, scientists have been able to make these same changes in lab mice in a relative blink of an eye.

The new technique using stem cells and gene editing is a major accomplishment, and one that the team is hoping will reveal more about how the rearrangement of chromosomes can influence the way that animals evolve over time.

It's in chromosomes those strings of protein and DNA inside cells that we find our genes, inherited from our parents and blended together to make us who we are.

For mammals like mice and us humans, chromosomes typically come paired. There are exceptions, such as in sex cells.

Unfertilized embryonic stem cells are usually the best starting place for tinkering with DNA. Lacking that additional set of chromosomes provided by a sperm cell, though, deprives the cells of an important step in negotiating which genes in which chromosomes will be marked active to do the job of building a body.

This process called imprinting was a stumbling block for engineers keen to restructure large chunks of the genome.

"Genomic imprinting is frequently lost, meaning the information about which genes should be active disappears in haploid embryonic stem cells, limiting their pluripotency and genetic engineering," says biologist Li-Bin Wang from the Chinese Academy of Sciences.

"We recently discovered that by deleting three imprinted regions, we could establish a stable sperm-like imprinting pattern in the cells."

Without those three naturally imprinted regions, lasting chromosome fusion was possible. In their experiments, the researchers fused two medium-sized chromosomes (4 and 5) and the two largest chromosomes (1 and 2) in two different orientations, resulting in three different arrangements.

The fusion of chromosomes 4 and 5 was the most successful in terms of the genetic code being passed on to the mice offspring, although breeding was slower than normal.

One of the 1 and 2 fusions produced no mice offspring, while the other produced mice offspring that were slower, larger, and more anxious than those from the fusion of chromosomes 4 and 5.

According to the researchers, the drops in fertility are down to how the chromosomes separate after alignment, which doesn't happen in the normal way. It shows that chromosomal rearrangement is crucial to reproductive isolation a key part of species being able to evolve and stay separate.

"The laboratory house mouse has maintained a standard 40-chromosome karyotype or the full picture of an organism's chromosomes after more than 100 years of artificial breeding," says biologist Zhi-Kun Li, also from the Chinese Academy of Sciences.

"Over longer time scales, however, karyotype changes caused by chromosome rearrangements are common. Rodents have 3.2 to 3.5 rearrangements per million years, whereas primates have 1.6."

To put this into context, rare leaps in chromosomal rearrangement have helped direct the evolutionary paths of our own ancestors. Chromosomes that remain separate in gorillas, for instance, are fused into one in our human genome.

Those types of changes can occur once every few hundred millennia. While the genetic edits made here in the lab were on a relatively small scale, the signs are that they could have some dramatic effects on the animals involved.

It's still early days this is a scientific first after all but further down the line, there might be the opportunity to correct misaligned or malformed chromosomes in human bloodlines. We know that in individuals, chromosome fusions and relocations can lead to health problems including childhood leukemia.

"We experimentally demonstrated that the chromosomal rearrangement event is the driving force behind species evolution and important for reproductive isolation, providing a potential route for large-scale engineering of DNA in mammals," says Li.

The research has been published in Science.

Originally posted here:
Scientists Just Genetically Edited a Million Years of Evolution Into Mouse DNA - ScienceAlert

How much do you know about your family tree? Could you name every branch going back for generations, or do you only know the names of a few leaves hanging close to you? Thankfully, whether your ancestors kept meticulous records or you were adopted and relocated halfway across the world as an infant, DNA technology has become incredibly advanced, and we all have access to our backgrounds through simply submitting a mouthful of saliva.

Unfortunately, however, the results of a DNA test are not always what curious participants had hoped for. After optimistically submitting their samples hoping to find out precisely which Eastern European cuisine they should be preparing on holidays, some people receive their results and are left questioning everything they know about their family members. Weve gathered some of the most amusing, shocking and upsetting discoveries made from taking DNA tests, that have been shared on the 23andMe subreddit, and listed them below for you to read. I sincerely hope you dont have any devastating stories of your own from having tests like this done, but if you do, know that youre not alone.

Keep reading to also find an interview with host of the DNA Surprises Podcast, Alexis Hourselt, and then if youre interested in reading even more stories about DNA tests revealing scandalous family secrets, we recommend checking out this Bored Panda article next.

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50 Times People Took A DNA Test And Found Out More Than They Wanted To - Bored Panda

Farrah Khilji-Holmes, 52, met her new-found sibling Steve Bolton, 62, for the first time after he travelled to the UK from Canada to see her and her relatives in person. They had the same dad, Dr Mohammad Elijaz Khilji, but different mums and didn't know anything about each other until they sent their DNA tests off and they matched.

Farrah reached out to Steve when his name came back as a match and after chatting for 18 months, Steve flew to meet Farrah in her hometown of Pontefract.

Farrah said: "I only logged on as a joke to see if I was switched at birth. Its been a bit of a running joke in our family for years. So I did a DNA test and made my mum do one too. But it came back with a close match to a man that it said was a first cousin or closer, but it couldnt be sure because there was a wide range.

"I was sat in the pub when a message came through from Steve and I shouted out Ive got a brother! Its absolutely like seeing dad in the flesh. My friends who have seen him say hes the spitting image of dad.

Dr Khilji had a relationship with Steves mum Pamela in London in the 1960s before returning to Pakistan without knowing she was pregnant with his child. Sadly, Pamela died when Steve was just seven and Dr Khilji died in 1998 having never learnt that he had another son.

In the meantime, he fathered children in Pakistan and when he returned to the UK, he had two children from a relationship with Sue Burton - Farrah and her sister Zarah.

Farrah said: "Dad was a big part of all our lives, if he'd known about Steve, he would have ensured he was part of our family too. He took an active role in all his children's lives and there is no way dad would have seen any of his children taken into care."

After his mum died, Steve spent time in a orphanage before his grandparents took him to Jamaica where his mum was born. But when his grandmother got sick, he was placed back in an orphanage in Jamaica before being adopted by a Canadian family and he lived in Toronto from the age of 13.

He said that after his adopted mum died he got his birth certificate and started looking for his dad and two years ago set about researching his family history and sent off a DNA sample that returned a couple of cousins. But was about to give up when he got a message from Farrah out of the blue to ask if he was her brother.

Steve said: After youve been waiting for so long its hard to believe its happened. Its completely surreal, I didnt know how to process it. I got a couple of hits from cousins, but I was about to cancel my membership when Farrah messaged. I hope this encourages other people who have been adopted to do their research because it's really amazing."

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Yorkshire woman who took DNA test as a joke discovers she has a half-brother - The Yorkshire Post

DUBLIN, Aug. 26, 2022 /PRNewswire/ -- The "Global Viral Vectors and Plasmid DNA Manufacturing Market (2022-2027) by Product Type, Application, Geography, Competitive Analysis and the Impact of Covid-19 with Ansoff Analysis" report has been added to ResearchAndMarkets.com's offering.

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The Global Viral Vectors and Plasmid DNA Manufacturing Market is estimated to be USD 901.01 Mn in 2022 and is expected to reach USD 2752.97 Mn by 2027, growing at a CAGR of 25.03%.

Market dynamics are forces that impact the prices and behaviors of the Global Viral Vectors and Plasmid DNA Manufacturing Market stakeholders. These forces create pricing signals which result from the changes in the supply and demand curves for a given product or service. Forces of Market Dynamics may be related to macro-economic and micro-economic factors.

There are dynamic market forces other than price, demand, and supply. Human emotions can also drive decisions, influence the market, and create price signals. As the market dynamics impact the supply and demand curves, decision-makers aim to determine the best way to use various financial tools to stem various strategies for speeding the growth and reducing the risks.

Company Profiles

The report provides a detailed analysis of the competitors in the market. It covers the financial performance analysis for the publicly listed companies in the market. The report also offers detailed information on the companies' recent development and competitive scenario. Some of the companies covered in this report are Merck KGaA, Lonza, FUJIFILM Diosynth Biotechnologies, Thermo Fisher Scientific, Cobra Biologics, Catalent, etc.

Countries Studied

America (Argentina, Brazil, Canada, Chile, Colombia, Mexico, Peru, United States, Rest of Americas)

Europe (Austria, Belgium, Denmark, Finland, France, Germany, Italy, Netherlands, Norway, Poland, Russia, Spain, Sweden, Switzerland, United Kingdom, Rest of Europe)

Middle-East and Africa (Egypt, Israel, Qatar, Saudi Arabia, South Africa, United Arab Emirates, Rest of MEA)

Asia-Pacific (Australia, Bangladesh, China, India, Indonesia, Japan, Malaysia, Philippines, Singapore, South Korea, Sri Lanka, Thailand, Taiwan, Rest of Asia-Pacific)

Story continues

Competitive Quadrant

The report includes Competitive Quadrant, a proprietary tool to analyze and evaluate the position of companies based on their Industry Position score and Market Performance score. The tool uses various factors for categorizing the players into four categories. Some of these factors considered for analysis are financial performance over the last 3 years, growth strategies, innovation score, new product launches, investments, growth in market share, etc.

Ansoff Analysis

The report presents a detailed Ansoff matrix analysis for the Global Viral Vectors and Plasmid DNA Manufacturing Market. Ansoff Matrix, also known as Product/Market Expansion Grid, is a strategic tool used to design strategies for the growth of the company. The matrix can be used to evaluate approaches in four strategies viz. Market Development, Market Penetration, Product Development and Diversification.

The matrix is also used for risk analysis to understand the risk involved with each approach. The analyst analyses the using the Ansoff Matrix to provide the best approaches a company can take to improve its market position. Based on the SWOT analysis conducted on the industry and industry players, the analyst has devised suitable strategies for market growth.

Why buy this report?

The report offers a comprehensive evaluation of the Global Viral Vectors and Plasmid DNA Manufacturing Market. The report includes in-depth qualitative analysis, verifiable data from authentic sources, and projections about market size. The projections are calculated using proven research methodologies.

The report has been compiled through extensive primary and secondary research. The primary research is done through interviews, surveys, and observation of renowned personnel in the industry.

The report includes an in-depth market analysis using Porter's 5 forces model and the Ansoff Matrix. In addition, the impact of Covid-19 on the market is also featured in the report.

The report also includes the regulatory scenario in the industry, which will help you make a well-informed decision. The report discusses major regulatory bodies and major rules and regulations imposed on this sector across various geographies.

The report also contains the competitive analysis using Positioning Quadrants, the analyst's Proprietary competitive positioning tool.

Key Topics Covered:

1 Report Description

2 Research Methodology

3 Executive Summary

4 Market Dynamics4.1 Drivers4.1.1 Increasing Capacities by Manufacturers Owing to Rising Demand4.1.2 Rise in Prevalence of Cancer, Viral Infections, and Genetic Disorders4.1.3 Increase in Awareness Regarding Gene Therapies4.2 Restraints4.2.1 High Cost Associated with Gene Therapies4.2.2 Stringent Government Regulations4.3 Opportunities4.3.1 The Rise in the Development of Allogeneic and Autologous Cell Therapy4.3.2 Increase in Funding for R&D Activities Pertaining to Gene Therapy4.4 Challenges4.4.1 Involved Risks For Mutagenesis and Other Obstruction in Gene Therapy

5 Market Analysis5.1 Regulatory Scenario5.2 Porter's Five Forces Analysis5.3 Impact of COVID-195.4 Ansoff Matrix Analysis

6 Global Viral Vectors and Plasmid DNA Manufacturing Market, By Product Type6.1 Introduction6.2 Plasmid DNA6.3 Viral Vector6.4 Non-viral Vector

7 Global Viral Vectors and Plasmid DNA Manufacturing Market, By Application7.1 Introduction7.2 Cancer7.3 Genetic Disorder7.4 Infectious Disease7.5 Other Applications

8 Americas' Viral Vectors and Plasmid DNA Manufacturing Market8.1 Introduction8.2 Argentina8.3 Brazil8.4 Canada8.5 Chile8.6 Colombia8.7 Mexico8.8 Peru8.9 United States8.10 Rest of Americas

9 Europe's Viral Vectors and Plasmid DNA Manufacturing Market9.1 Introduction9.2 Austria9.3 Belgium9.4 Denmark9.5 Finland9.6 France9.7 Germany9.8 Italy9.9 Netherlands9.10 Norway9.11 Poland9.12 Russia9.13 Spain9.14 Sweden9.15 Switzerland9.16 United Kingdom9.17 Rest of Europe

10 Middle East and Africa's Viral Vectors and Plasmid DNA Manufacturing Market10.1 Introduction10.2 Egypt10.3 Israel10.4 Qatar10.5 Saudi Arabia10.6 South Africa10.7 United Arab Emirates10.8 Rest of MEA

11 APAC's Viral Vectors and Plasmid DNA Manufacturing Market11.1 Introduction11.2 Australia11.3 Bangladesh11.4 China11.5 India11.6 Indonesia11.7 Japan11.8 Malaysia11.9 Philippines11.10 Singapore11.11 South Korea11.12 Sri Lanka11.13 Thailand11.14 Taiwan11.15 Rest of Asia-Pacific

12 Competitive Landscape12.1 Competitive Quadrant12.2 Market Share Analysis12.3 Strategic Initiatives12.3.1 M&A and Investments12.3.2 Partnerships and Collaborations12.3.3 Product Developments and Improvements

13 Company Profiles 13.1 Audentes Therapeutics13.2 Batavia Biosciences13.3 BioMarin Pharmaceutical13.4 BioNTech IMFS13.5 Catalent13.6 Cobra Biologics13.7 FUJIFILM Diosynth Biotechnologies13.8 Genezen laboratories13.9 Lonza13.10 Merck KGaA13.11 Miltenyi Biotec13.12 RegenxBio13.13 SIRION Biotech 13.14 Takara Bio13.15 Thermo Fisher Scientific13.16 Virovek 13.17 Waisman Biomanufacturing13.18 Wuxi Biologics

14 Appendix

For more information about this report visit https://www.researchandmarkets.com/r/n1d1m0

Media Contact:

Research and MarketsLaura Wood, Senior Managerpress@researchandmarkets.com

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Originally posted here:
Global Viral Vectors and Plasmid DNA Manufacturing Market (2022 to 2027) - Featuring Audentes Therapeutics, Batavia Biosciences and BioMarin...

An increasing number of pregnant Norwegian women take extended foetal diagnostic tests in Denmark. One of the tests is analysed in China, and DNA from both the mother and foetus may end up with the Chinese authorities.

If the Chinese authorities really want to, they will get access to the genetic data. This is the general relationship between Chinese companies and the state. You cannot know what happens to your own and the unborn child's DNA, Mette Halskov Hansen, professor in Chinese Studies at the University of Oslo, tells the Norwegian Biotechnology Advisory Boards journal GENialt (link in Norwegian).

A noninvasive prenatal testing (NIPT) test is an analysis of a foetus' DNA to detect developmental abnormalities. It is done by taking a blood sample from the pregnant woman.

In Norway, it is only permitted to test for three different chromosomal abnormalities, but in Sweden and Denmark several broader NIPT tests are available.

One of these, Nifty, is much cheaper than the others sold in Scandinavia. It has been developed and analysed by the Chinese company BGI, and the company itself writes that Chinese authorities are given access to genetic data if national security considerations dictate this.

The Norwegian Consumer Council is now warning pregnant women.

As far as we can tell, this transfer of samples is not within European data protection legislation (GDPR). It is generally not allowed to transfer personal data to countries with far-reaching surveillance laws, where you do not have satisfactory protection in line with European legislation, Director Inger Lise Blyverket of the Norwegian Consumer Council says.

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The Norwegian Consumer Council warns that Norwegian DNA is being sent to China - Sciencenorway

YPSILANTI, Mich. (WXYZ)"We wouldn't have found out who did it without the DNA," said the mother of an 11-year-old girl who was lured off her bicycle in Ypsilanti, kidnapped, and raped.

It happened in May, but the results of DNA testing have identified 35-year-old Brandon Hutson as the assailant, according to Ypsilanti Police.

Hutson is from Detroit but he was recently arrested in Grand Rapids.

He's been arraigned on multiple charges including kidnapping and first degree criminal sexual conduct.

Hutson's bond has been set at $250,000 cash or surety.

Hutson's DNA was already in CODIS, the federal Combined DNA Index System, from a 2012 robbery case in Wayne County for which he spent time in prison.

The Ypsilanti girl, who has high functioning autism, was kidnapped and assaulted in May after her mom said she snuck out of the house to ride her bike while she was taking a nap after work.

"When I woke up, it was like 11pm, and she was gone," the girl's mother told 7 Action News. "I immediately called the police and the police found her bike around the corner but they didn't find her."

"She would have tried to take the bike with her. I think he forced her to get in the car without her bike," she added.

Shortly after police released details of the missing girl, she was released and located in another neighborhood in Ypsilanti where someone called 911.

The girl was rushed to an area hospital where she underwent rape kit testing.

"She's more scared to do certain things, like leaving my side, because she knows that something bad might happen."

In court during his arraignment, Hutson's attorney said he adamantly denies the allegations.

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Ypsilanti mom credits DNA, detective with getting daughter's alleged rapist behind bars - WXYZ 7 Action News Detroit