Category Archives: Tms

1. Breakthrough in brain stimulation offers cautious hope for depression  Harvard Health
2. D-cycloserine enhances TMS treatment for depression  Healio
3. Antibiotic May Enhance TMS, Improve Depression Outcomes  Medscape
4. Repurposed Antibiotic Increases Efficacy of Brain Stimulation for Depression, Study Shows  Technology Networks
5. Treating Major Depressive Disorder With D-Cycloserine Plus Theta-Burst Stimulation  DocWire News
6. View Full Coverage on Google News

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Breakthrough in brain stimulation offers cautious hope for depression - Harvard Health

CADIZ, Ohio (WTRF) What would you do to change your life?

For the far too many veterans and first responders caught in the struggles of PTSD, the answer is just about anything.

Last year 7News brought you to a small room inside the Harrison County Sheriffs Department where a ground-breaking treatment was pulling people away from the lingering trauma of military service and towards a new-life.And because of the life-altering success, the program is expanding across Ohio.

I just reached the point in my life, you know, I couldnt stand what I was doing. I tried to commit suicide once. My daughter just ran to the basement screaming no daddy no.

For 50-years, Marine Corps veteran Terry Wildman carried what happened in the jungles of Vietnam with him.

He sought treatment, and it helped, but it wasnt enough.Then Wildman found TMS in Harrison County.

A lot of guys are coming in here having post-traumatic stress to severe levels, I mean, to where theyre thinking about doing bad things and this gives them hope.

Dirk Harkins has faced his own struggles with PTSD.

He too had TMS treatment change his life, but had to travel to Texas for it.

To know that I had brothers and sisters back here in Ohio struggling from the same thing that didnt have the ability to get this like I did, the fight was on.

The fight continues to expand the treatment in Ohio, but its getting easier.

First, this program was made possible through a collaboration with Ohio State Universitys Wexner Medical Center. It allowed the TMS treatment to come to the Harrison County Sheriffs Department for veterans.

30 days, life-changing results: The new treatment available to veterans in the Ohio Valley

When that contract ended; Harkins, Ohio State Senator Frank Hoagland, and others got to work grying to get funding from the state. They did, and now TMS will be more widely available; not just to veterans, but first responders too.

You may be able to be better focused, better response times. We work with people all over the country and we hear my wife likes me again, my children tolerate me again, Im able to sleep better, focus better, concentrate. Then, how does that impact your work?

TMS treatments work with magnets. As Harkins describes it, it re-boots the brain.

There are two types of TMS treatment, and what a veteran or first responder needs is determined by medical experts and an initial EEG.

Currently, sTMS is whats available at the Harrison County Sheriffs Department. Its 30-minute sessions, five days a week for 30-days. With this new program, eTMS will be a possibility. Its 100-times the output and lasts about 14-16 minutes at a time, with one session a day for 30-days.

Some parts of the program may also pair counseling with TMS treatments.

The treatment is FDA approved for migraines, anxiety and OCD, but its also helping participants with a critical basic function.

They go from restless nights to a more sound sleep.

I havent slept for 50-years. Every night of my life Im back in the jungle. Somethings wrong. I couldnt do what I wanted to do.

I couldnt believe what was happening (after the treatment). I thought my God, where has this been years and years ago.

While the treatments are five-days a week for 30-days, the initial results come fairly quickly.

Even after youre done, the program has a way to make sure the benefits of TMS And eTMS dont wear off.

Charles company developed technology that works like a watch, to track data and notify doctors when a veteran may be slipping backwards.

Lets say in a couple months your sleep starts going down. We are notified by our technology and the doctors are notified. The peer support people are notified. Well give you a call and say is something going on in your life?.

Harkins calls it a quality of life machine.

He explained all it takes is commitment to the program to get life-changing results.

Were seeing that its reducing opioid cravings, alcohol, its relieving pain, mobility. Its amazing some of the things Im seeing how its working.

TMS treatments will be available in Barnesville, New Lexington, Columbus and Youngstown at the end of this month.

The initial center at the Harrison County Sheriffs Department will be there too.

Veterans or first responders who think they could benefit from this treatment can call Dirk Harkins at 740-491-7125.

There will also be a website up and running soon where veterans and first responders can sign up for the TMS program. When its active, 7News will be sure to link it here.

Read more from the original source:

Life-changing treatment program in Ohio expanding for veterans and first responders - WTRF

The feature people are most excited for, earning 61 percent of the vote, is the new open-world experience of "Pokmon Scarlet and Violet." Unlike previous iterations in the series, this new open-world has no guardrails or story order. According to the game's website, you can go where you want, when you want(for the most part) on your "Scarlet and Violet" journey. This is expected to provide much more of an open experience than "Pokmon Legends: Arceus."

Coming in a distant second place (with 13 percent of the vote) was the Auto Battle feature. While you're traversing the open world, this feature allows you to send yourPokmon in any direction you choose. It'll then pick up items in its path and automatically fight any monster it runs into.

Tied for third and fourth place in the poll were the three new starters Sprigatito, Fuecoco, and Quaxly and the ability to craft TMs. The feature players are least excited for, Tera Raid Battles, garnered only 6 percent of the vote. These battles involve four players taking on a wild TerastallizedPokmon within a certain limit of time.

All in all, while there are many exciting new features in"Pokmon Scarlet and Violet," none of them seem to compare to the open world experience. Hopefully, it lives up to the fan hype.

Go here to read the rest:

Over 60% Of Pokemon Fans Are Most Excited For This Feature In Scarlet & Violet - SVG

MISSISSAUGA, ON, Oct. 18, 2022 /PRNewswire/ - FR8Focus is a new mobile application on the market that proves to be the next step in the visual, real-time digitization of freight and asset tracking for North American carriers. In collaboration with a leading private carrier over the last three years, the application is highly refined and addresses real-world pain points of transportation.

Allowing carriers to connect, mobilize, track and manage their fleets in real-time, FR8Focus was developed to integrate seamlessly into all facets of less-than-a-truckload (LTL) and truckload operations (TL). NorthStar Digital Solutions COO, Dave Brajkovich, explains, "FR8Focus is about more than a single piece of technology. It's about flawlessly combining an assortment of technologies to solve industry-wide issues. Operations can see their entire fleet(s) on the road at a glance, communicate with drivers instantly and adjust schedules ad hoc." Mr. Brajkovich continues, "From a carrier's customer standpoint, we have eliminated a lot of frustration. When they see real-time route flows and receive instant notifications, there is no longer a need to ask where their shipment is."

The application provides agility and visibility while reducing the antiquated processes of paper-shuffling from hours to minutes, even seconds, by completely digitizing operational workflow. This significantly lessens carrier overhead, eliminating all manual labour previously required to handle documentation. PODs are scanned by the drivers and uploaded instantly to backend TMS systems to provide next-minute customer invoicing. Customs documentation is uploaded immediately to expedite shipment release and border crossing. This is backed by industry-leading document capture resolution mitigating error and ensuring no carriers are leaving money on the table.

Radaro's Joe Thull, Head of North America, comments, "Working with a large LTL provider over these past two years allowed us to co-create a solution that has solved many of the current LTL marketplace challenges while being simple to use, yet powerful to scale." Mr. Thull adds, "Our solution was developed with the carrier, the customer and the driver in mind, resulting in truly intuitive systems where workflows anticipate each step. FR8Focus complements existing tech stacks to allow for efficient integration and avoid the headache of replacing systems essential to running their business."

Mr. Brajkovich exclaims, "Customers, partners and transportation leaders are showing significant interest and excitement. Not just for the impact FR8Focus can have on their bottom line, but for how quickly we can integrate. Our ROIs are well-established and the infrastructure is in place. We can integrate into a small fleet or trial portion of a larger fleet within a couple of days." He concludes, "Waiting for information is a non-starter for this day and age. With FR8Focus, we're connecting the road to the back office!"

FR8Focus is alleviating operational pain points in the LTL and TL marketspace and delivering solutions with speed, accuracy and simplicity. Its use-case provides a detailed look into the real insights gained by one of Canada's largest privately owned LTL carriers.

Those interested in scheduling a demonstration or learning more about the application are encouraged to contact Radaro or NorthStar Digital Solutions.

About Radaro:

Radaro is an enterprise technology platform that streamlines and optimizes LTL and freight deliveries. Our leading UX/UI places the customer at the center and is simple to deploy, easy to understand andeffortlessly scalable. Radaro scheduling, routing and dispatching enables real-time visibility for service providers and brings control over your logistics and brand experience during delivery.

Our global customers benefit from our purpose-built, modern technology stack that seamlessly integrates end-to-end with your current environment i.e., TMS platform. Radaro partners with leading retail, grocery, LTL logistics, TMS providers, manufacturing, healthcare and service industries to bring innovative solutions to market. For more information, visit radaro.com.au/fr8focus

About NorthStar Digital Solutions:

A new way of connecting the supply chain to you. NorthStar infuses the digital experience into transportation and supply chain industries through powerful, efficient and seamless technology platforms. Known as systems integrators, they provide unified end-to-end solutions and offer direct connectivity streams to associated partners, carriers, shippers, brokers and consumers. For more information, visit northstardigital.solutions

SOURCE NorthStar Digital Solutions

Original post:

Radaro and NorthStar Digital Solutions partner to solve industry-wide process gaps in LTL & TL transportation - PR Newswire

FREMONT, Calif. (PRWEB) October 17, 2022

Avalanche Technology, the leader in next generation MRAM technology, today announced that it has entered into an agreement with TMS-Elektronik, to represent Avalanche in the sales and support of its STT-MRAM-based discrete Persistent SRAM (P-SRAM) non-volatile memory products in the Republic of Turkey. In support of this new relationship, Avalanche Technology will join the TMS-Elektronik team at the upcoming SAHA Expo 2022 in Istanbul, October 25th-28th.

With benchmark high reliability, high endurance and low power, combined with high access speed, Avalanches STT-MRAM products will bring significant benefits to our customers who develop boards and systems for aerospace and industrial applications, said Eren aaan, Co-founder and CEO of TMS Elektronik. Avalanches portfolio of STT-MRAM-based discrete memory devices complements and completes our portfolio of discrete solutions and embedded systems. We are excited to add Avalanche to our portfolio of partners.

TMS-Elektronik will help us reach more European customers who want to use Avalanche P-SRAM to innovate around Industrial, IoT and Aerospace products, and extend our reach into segments that require high reliability combined with non-volatility, said Danny Sabour, VP of Sales & Marketing at Avalanche Technology. TMS-Elektronik will enable us to have world-class local support for our customers in the vibrant high-tech market of Turkey.

Avalanches serial Persistent SRAM (P-SRAM) devices are based on its latest generation of Spin Transfer Torque Magnetoresistive RAM (STT-MRAM) technology, touting industry leading endurance and densities for non-volatile memory all with a high reliability backbone (no external ECC, wear leveling, battery or shielding needed) and easy to use timings of an SRAM. As true random-access memory devices, allowing reads and writes to occur randomly, they are ideal for applications that require storing and retrieving data without large latency penalties.

Industrial Grade solutions support densities up to 16Mb with a variety of interfaces (SPI, QSPI, parallel) and performance options up to 108MHz SDR/54MHz DDR for serial and 35ns for parallel. For Hi-Rel and Aerospace applications, our solutions provide densities from 16Mb to 8Gb and endurance of 10^16 for true unified memory support and optimized Size, Weight, Power and Cost (SWAP-C).

More Information

More information about Avalanche P-SRAM products is available at https://www.avalanche-technology.com/products/discrete-mram.

More information about the 2022 SAHA Expo Defence & Aerospace Exhibition is available at https://www.sahaexpo.com/defence-aerospace-exhibition.

About Avalanche Technology

Avalanche Technology Inc. is the leader in next generation Perpendicular STT-MRAM technology, accepted as the front-runner to replace traditional Flash and SRAM for unified memory architectures in future SOC systems, delivering high performance and low power at 55, 40, 28 and 22nm with scalability beyond 14nm. With a proven STT-MRAM portfolio at multiple geometry nodes combined with an intellectual property portfolio of over 300 patents and applications, Avalanche Technology is delivering on the promise of enabling the next generation of scalable unified memory architecture for industrial, IoT, aerospace and storage applications, making it the true Next Generation MRAM Company. For more information, visit us online at https://www.avalanche-technology.com.

About TMS-Elektronik

TMS-Elektronik was founded in 2004 as a representative and distribution firm for leading semiconductor, RF Microwave and interconnect solutions primarily targeting defense, aviation, space, and telecommunications industries within Turkey. TMS-Elektronik invests in innovative products and services with the help of partners to provide solutions to customers in support of demanding next generation architectures. For more information, visit us online at http://www.tms-elektronik.com/en.

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Avalanche Technology and TMS-Elektronik Announce Representation Agreement for the Republic of Turkey - PR Web

DUBLIN--(BUSINESS WIRE)--The "Talent Management Software (TMS) Market: Global Industry Trends, Share, Size, Growth, Opportunity and Forecast 2022-2027" report has been added to ResearchAndMarkets.com's offering.

The global talent management software (TMS) market reached a value of US$ 10.4 Billion in 2021. Looking forward, the publisher expects the market to reach US$ 25.8 Billion by 2027, exhibiting a CAGR of 16.35% during 2021-2027.

A talent management software (TMS) refers to a workforce management application that involves performance management, strategic hiring and employee development. It enables organizations to track and manage their employees by setting goals, identifying and closing skill gaps, providing personalized development plants and facilitating appraisals.

It provides employers with the tools to accurately manage, evaluate, and compensate based on employee performance. This enables organizations to foster a culture of career development and improve the overall performance of the employees. Owing to this, it finds extensive applications across the banking, financial services and insurance (BFSI), healthcare, information technology (IT), retail, and manufacturing industries.

Talent Management Software (TMS) Market Trends

The increasing penetration rate of cloud-based platforms, along with the adoption of mobile-based personnel management systems, is one of the key factors driving the growth of the market. Organizations and human resource professionals are increasingly adopting software-as-a-service (SaaS) platforms for automating scouting, identifying and acquiring new talents from the talent pools and retaining the existing talent.

A TMS also enables in streamlining the recruitment process, reinforce workforce culture, provide agile learning opportunities and identify the top performers. Additionally, various technological advancements, such as the utilization of machine learning (ML) and artificial intelligence (AI), are also acting as growth inducing factors.

The software uses optical trackers to monitor individuals and to identify market trends and patterns through transactional activities and analytical inputs. Other factors, including the growing need to replace traditional talent management methods to optimize the utilization of resources and improve the quality of hiring decisions, are expected to drive the market further.

Key Questions Answered in This Report:

Competitive Landscape:

The report has also analysed the competitive landscape of the market with some of the key players being

Key Market Segmentation:

Breakup by Component:

Breakup by Deployment Type:

Breakup by End User:

Breakup by Vertical:

Breakup by Region:

North America

Europe

Latin America

Middle East and Africa

For more information about this report visit https://www.researchandmarkets.com/r/hwu2wv

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Global Talent Management Software (TMS) Market Report 2022: A $25+ Billion Market by 2027 - Industry Trends, Share, Size, Growth, Opportunities and...

Martin Pnek asked me to write a foreword to a new edition of a Czech translation of Adam Smiths The Theory of Moral Sentiments. He gave me permission to post my original English-language text here. The book will be published in 2023 by the Liberln Institut, edited by Pavel Chalupnek, and translated by Hana Rogalewiczov & Vladimr Rogalewicz.

Foreword

Have you noticed? Now you hear a lot about Adam Smiths The Theory of Moral Sentiments (TMS). I think thats good. Of all the books Ive ever read, TMS is my favorite (Ive never read the Bible).

Did you know that from about 1800 to, say, 1976, TMS was consigned to oblivion? During Smiths life, TMS was quite favorably received. Then, after 1790, it was widely disparaged and fell into oblivion, as the exceptional Glenn Morrow observed in 1927. Now, its back in a big way. How many other books are there that resided in oblivion for so longabout 175 yearsand then came back in a big way? Curious, no?

TMS is a curious work, even mysterious. I think it is great that Czech readers have the present resource to get acquainted with the work. TMS abounds in illustrations, so the book does not lack concreteness. Still, it is a complex work. Multi-layered, you might say; and when there are layers beneath the surface, even between the lines, readers will puzzle over just what it is that is down there. (Or should we say up there?) Scholars continue to disagree.

Something about TMS is indisputable: the breadth of its votaries. Admirers of TMS range across academic and scholarly fields and disciplines, across countries and continents, and, most remarkably, across landscapes of political ideology. Today, Smiths ghost is surely pleased to see us meeting to converse over how his text should be interpreted.

Today, Smith scholars agree on some important things. They generally agree that The Wealth of Nations (WN) should be seen as an extension of, or annex to, TMS. They also generally agree that, although the two great works differ greatly in certain aspects, such as the language used and the distance or warmth of the authors voice, there is no underlying tension between the two works. The two works emphasize different things, and to some extent treat different things, but there is no inconsistency between them. Indeed, most of the Smithian contrarietiesthat is, seeming contradictionsthat have engaged scholars are either intra-TMS or intra-WN.

For the reader of the Czech translation, the subtlety and richness of TMS means that reading the work in translation may not work. My feeling, however, is that reading the translation can help one to get to a good understanding of TMS. But achieving a good understanding will require moving on to Smiths words, as he wrote them in English. I have spent many decades studying TMS. Spending a year with the Czech translation is a good way to get acquainted with TMS. Indeed, it might be the best way for Czechs to get acquainted.

As for Smiths words, as he wrote them: Scholars and editors properly emphasize that the work changed considerably from the first edition of 1759 and the sixth edition of 1790. The TMS of 1790 is a larger and richer work than the TMS of 1759. Smith died in 1790, a couple of months after the final edition appeared. The changes made in 1790, taken together, exceed all the changes made in all of the previous editions, in extent and significance. Did the changes ever reverse, or retract, what was said in an earlier edition? I would say, basically, no; Smith never exactly reversed or retracted what he meant in the earlier edition. (Some argue that later editions substantially retract the evident theism of the first edition, but the evidence is somewhat ambiguous.) Smiths thinking surely evolved somewhat between 1759 and 1790, but I think it plausible that if the 1790 Adam Smith and the 1759 Adam Smith were to meet privately and converse, the 36-year-old Smith would have found little in the conversation of the 67-year-old Smith with which to disagree. On the changes to TMS through the six editions, see Erik Matsons article in the Journal of Markets and Morality (2021).

I made a getting-started-on-TMS video you might find helpful (you can watch at 1.5 speed.):

One other thing to keep in mind, that commentators do not say enough: Dont take Smiths representations of what other thinkers thought too seriously. That is, where Smith says that Hume or Hutcheson or the Stoics or the books of casuistry said X, assume that he is positing a foil. He uses that foil to provide a contrast to his own thinking. In associating X with some thinker, Smith is not necessarily to be trustedthough perhaps he makes the association in a way that he supposes his reader will come to see as not entirely without irony or playfulness.

I suspect that in personal interaction, Smith carried himself with less playfulness than his best friend David Hume. But something said about Hume perhaps also had Smith in mind. Smiths younger contemporary Dugald Stewart wrote: Dr. [William] Robertson used frequently to say, that in Mr. Humes gaiety there was something which approached to infantine; and that he had found the same thing so often exemplified in the circle of his other friends, that he was almost disposed to consider it as characteristical of genius. When reading TMS, we commune with a companion who mastered an equipoise between gravity and playfulness.

Originally posted here:

A Foreword to Adam Smith's The Theory of Moral Sentiments - Independent Institute

A huge change is underway as Germanys largest telecommunications company, Deutsche Telekom, has announced to buy only electric company cars from 1 January 2023. Staff in Germany will have a choice between 33 EV models. The move is part of the Groups broader sustainability initiatives.

Deutsche Telekom announced the phase-out of the combustion engine in new company cars on Thursday at its first Sustainability Day. A spokesperson stressed that the phase-out relates to a part of the vehicle fleet, namely the company cars, and not, for example, the service vehicles. Still, the transition will be relatively rapid since the new procurement rule will apply in Germany from the turn of the year. It is intended to be a first step toward converting the entire vehicle fleet to electric motors, as Telekom states.

This could have a sizeable impact. According to Telekom Mobility Solutions (TMS), a wholly owned subsidiary responsible for the vehicle fleet, the Telekom fleet comprises 23,000 company cars and service vehicles, making it one of the largest company fleets in Germany. Olga Nevska, TMS Managing Director, describes the phasing out of internal combustion engines on her LinkedIn profile as an important milestone on the way to sustainable, connected and demand-driven employee mobility. With 33 pure EV models in the portfolio, she says there is something to suit everyone.

Of course, the current long delivery times also affect Telekom. Just over a month ago, Nevska complained to the Handelsblatt about it. In the process, the equipment is sometimes still changed by the manufacturer. That makes the person placing the order dissatisfied and makes our work more difficult, she said. Telekom waited for 550 electric cars at the time, most scheduled to arrive in spring 2023, according to the German newspaper.

Independently of this, Telekom has synched the switch to fully electric vehicles with an extension of the service life of company vehicles from three to four years. This, too, is with a view to sustainability. In principle, the CO2 emissions of Deutsche Telekoms business vehicles in Germany were around 21,400 tons at the end of 2021. Electrification is expected to reduce emissions by 76 per cent to about 5,000 tons of CO2 by the end of 2026, so Telekom.

According to its managing director, TMS is turning from a fleet into a mobility provider. In this respect, electrification is just one of several transformation processes under the slogan of operational mobility. We take our responsibility as an employer very seriously and have been working for years to offer our employees sustainable mobility that meets their needs. The switch from combustion engines to electric motors plays a central role. At the same time, we are developing attractive offers that will reduce commuting on our roads and enable a convenient switch to the public, shared forms of mobility, Nevska said.

So, in addition to procuring and operating classic company cars or service vehicles, TMS is involved in sharing concepts and on-demand solutions. The company website informs that the company operates a car-sharing fleet, 8,000 salary conversion bicycles, an on-demand shuttle service for around 120,000 people a year, and micro-mobility offerings in the form of pool bikes, scooters and more.

The companys mobility network shall tighten. For those who want to do without their company vehicle altogether, our MaaS platform will soon be launched, which bundles a wide variety of means of transport in one app and makes it easier for all commuters to switch to the public, shared forms of mobility, the TMS boss announces. According to her data, 60 per cent of all employees still come to work in their cars. A figure that is expected to fall further.

Incidentally, Deutsche Telekom offers replacement mobility for the new electric company cars. This means that employees can borrow a combustion engine if necessary. According to Nevska, car subscription models are also becoming increasingly popular within the Group. These allow customers to switch to the vehicle type that suits their current situation. As early as spring 2022, 40% of new orders would be for electric vehicles in this way, the CEO told us in an earlier interview.

At the same time, the business customer division T-Systems takes a pioneering role in the Group. It started converting its business fleet worldwide to electric drives earlier this year. Telekoms international IT subsidiary plans to complete the project for the 1,400 company cars in Germany by 2025.

As a Group, Deutsche Telekom aims to be climate-neutral along the entire value chain (Scope 3) by 2040. For business operations, this target applies as early as 2025 (Scope 1-2). To achieve this, CO2 emissions must be reduced by around 95 per cent compared to 2017.

Our customers, but also our investors, consider it important that our company grows sustainably, said Telekom CEO Tim Httge. It is not only the price of the products that interest them but also the price paid by the environment. That is why we are redoubling our efforts, for example, to achieve climate neutrality and a circular economy.

>> Reporting by Cora Werwitzke, Germany.

telekom.com

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Deutsche Telekom to buy 100% electric company cars from 2023 - http://www.electrive.com

Transcranial Magnetic Stimulation (TMS) is a non-invasive stimulation procedure that uses transient electromagnetic fields to act in a focused manner on a particular brain region. It can be used as a therapy for depression, Parkinsons disease or obsessive-compulsive disorders in patients resistant to drug treatments. Researchers from the Paris Brain Institute also showed lasting effects of TMS in rehabilitation after a stroke.

Recording of intraneuronal electrical activity before and after TMS

It is generally considered that high intensity magnetic stimulation used in humans generate an electric field sufficient to modulate the activity of neurons: triggering nerve impulses encoding cerebral information and inducing plasticity phenomena in the neuronal networks of the targeted region.

However, although its therapeutic efficiency has been recognized in a number of cases, the mechanisms that allow TMS to restore or durably modify neuronal activities in the stimulated brain regions remain poorly understood.

For the first time, Manon Boyer and Sverine Mahon, respectively doctoral student and researcher in the team DYNAMICS OF EPILEPTIC NETWORKS AND NEURONAL EXCITABILITY in collaboration with Dr Antoni Valero-cabre Team FRONTLAB: FRONTAL FUNCTIONS AND PATHOLOGY(institutducerveau-icm.org)at the Brain Institute, have directly demonstrated the effect of low-intensity TMS on the excitability and spontaneous activity of neurons in the cerebral cortex, activity that allows these cells to communicate with each other and to transmit information to peripheral organs and muscles. This work is published in The Journal of Physiology.

The researchers combined the application of repeated low-intensity magnetic stimulation to the somatosensory cortex of an experimental model with intracellular recording of the electrical activity of the underlying neurons; a technique allowing to understand the effect of TMS seen from inside the neurons.

They showed that repetitive low intensity TMS can also trigger action potentials in neurons and induce plasticity expressed by a lasting decrease in the spontaneous activity of neurons, in their excitability and in the amplitude of synaptic events (reflecting a decrease in the transmission of information between neurons). These changes are not reproduced by directly stimulating the cells with an electric current of the same intensity, directly demonstrating the specific role of the magnetic field.

In conclusion, this work shows that low-intensity TMS has lasting effects on the excitability and discharge activity of neurons in the cortex and opens up new therapeutic avenues for pathologies in which cerebral hyperexcitability is observed, such as epilepsy or Tourettes syndrome. Indeed, in epilepsy, we observe an abnormally high electrical activity of a set of neurons in the cerebral cortex which then form an epileptic focus.

This work shows that low-intensity TMS, a non-invasive therapy that can be easily deployed at the patients bedside, is a very promising approach for patients with epilepsy.

Reference:Boyer M, Baudin P, Stengel C, et al. In vivo low-intensity magnetic pulses durably alter neocortical neuron excitability and spontaneous activity. J Physiol. 2022;600(17):4019-4037. doi: 10.1113/JP283244

This article has been republished from the following materials. Note: material may have been edited for length and content. For further information, please contact the cited source.

Original post:

What Happens in the Brain During Transcranial Magnetic Stimulation? - Technology Networks

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TMS and SIS to vie for soccer championship - Saipan Tribune