Category Archives: Life Extension

Heres a bit of Angels news that surfaced today and should immediately enter the annals of team lore, but this piece of team history and trivia isnt of the oh, thats a neat bit of info variety, but the OMG, THIS TEAM IS KILLING MY WILL TO LIVE kind. Do you remember when the Angels and Mike Trout came to a deal on his six-year extension, that would have him signed through 2020? It was a great day to be an Angels fan, because they locked up the burgeoning baseball legend for $144.5 million while buying out two years of what could have been his free agency.

Its hard to not like what the Halos did there, getting that lightning that Eddie Bane caught in a bottle, and making sure it doesnt hit free agency till 2020 instead of 2017, but it was also a pretty big payday for Trout, so there was a sense that everybody walked away happy.

Notice how I said its hard not to like that extension, not impossible...because there IS one way, one circumstance, in which that 2014 negotiation could make me HATE that deal with the fire of a thousand suns, I just didnt know this particular circumstance existed until today.

If Mike Trout wanted to sign a lifetime deal with the Angels (meaning 14 or 15 years), and Arte Moreno said No, then suddenly that six-year extension becomes one of the dumbest things Ive ever seen from this team. According to a Jon Heyman piece from earlier today, thats exactly what happened, and Im now having to write this article using voice-to-text tools because Im so filled with instant rage that I can only see red right now.

Trout was the one exception, and in three years hell be a free agent barring a new try by the Angels. Trout set himself up for life with that rare, record six-year deal and will have a second bite at the apple, after he broached an extreme mega deal in talks (14 or 15 years, according to people familiar with those talks) before word came back that Angels owner Arte Moreno decided not to go for the lifetime deal for the two-year superstar, but hardly anyones repeating that strategy. Its no certainty they would have been able to work it out the super mega deal, anyway, as Trout seemed pleased at the middle ground of six. But it was quite an interesting thought put forth by Trouts side.

Man, here I was having a nice day, and all of a sudden I feel ill. The Angels had the best player in the universe asking to be with them for not only his youthful seasons, but for also his prime, late 20s/early 30s years, and they were like Nah, thats too long. We dont like having good players for that long, it makes us nervous. Im guessing that was the rationale, at least, since they had no problems signing up a declining Albert Pujols to a ten-year deal. Who am I kidding? There was NO rationale in that decision. Period.

Its not like the Angels didnt know what they had on their hands yet, either. When these talks were going on, Trout had already completed his age 20 & 21 seasons, during which he won a Rookie of the Year award, and came in 2nd in AL MVP voting not once, but twice. The writing was on the wall; he was going to change the game of baseball forever. On top of that, it was HIS idea...he was the one that floated it to the team, and they shot it down.

The Angels then tried to go for something in the 7-9 year range, but the two sides agreed on six years. I know that were still supposed to be able to look back at this whole ordeal and be happy with what we got, but imagine a world in which we knew the Angels had time to build around him. Imagine us not having to preemptively worry about where hell go once he does hit free agency after 2020. The Halos and us fans could be resting easy right now, knowing Trout wasnt going anywhere, and thered be time yet to put some great teams around him and win some real October hardware.

Nope. Arte Moreno said no. This is going to sting for awhile, folks. My only chance at being able to live with this knowledge is that, as Heyman noted in his article, we dont know for sure that they could have worked out a deal this big to begin with, so I am clinging on to that thought for dear life. Its all Ive got keeping my sanity in check right now. The only other option is facing this living nightmare, a world in which the Halos could have had Trout all to themselves, forever...and Arte Moreno said No. I shudder at the thought.

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Mike Trout wanting to be an Angel for life and Arte Moreno saying No is my worst nightmare come to life - Halo's Heaven

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APPETIZERS

WHERE MOST OF THE WORK IS DONE BEFORE YOU KNOW IT

MAGNESIUM REDUCES ALL-CAUSE MORTALITY, INCLUDING STROKE, HEART FAILURE, AND DIABETES

ARGININE FOR PAIN: SICKLE CELL DISEASE

RUTIN, A COLD MIMETIC, ACTIVATES BROWN ADIPOSE TISSUE TO INCREASE ENERGY EXPENDITURE FOR WEIGHT LOSS

PERSISTENT INFECTIONS CAN BE SILENT KILLERS: HELICOBACTER PYLORI

TIME IS ON MY SIDE YES, IT IS

WHATEVER YOU MAY THINK OF MR. TRUMP

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Life Extension News | March 2017 Issue | Life Enhancement ...

Quwa Defence News & Analysis Group

USAF seeks to expand F-16 life-extension program - Quwa Quwa Defence News & Analysis Group The U.S. Air Force is looking to expand its service-life extension program (SLEP) from 4000 additional hours to 5856 hours. and more »

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USAF seeks to expand F-16 life-extension program - Quwa - Quwa Defence News & Analysis Group

Floyd is a horticulturist with Texas AgriLife Extension Service. He can be reached at 498-4071 in Ector County or 686-4700 in Midland County or by email at Jeff.Floyd@ag.tamu.edu

Floyd is an Agri-Life Extension agent for Ector and Midland counties. To learn more, call the Ector County Extension office at 432-498-4072, or the Midland County Extension office at 432-686-4700, or email jeff.floyd@ag.tamu.edu.

Posted: Sunday, June 18, 2017 3:00 am

GARDENING: High humidity, poor airflow could rot your tomatoes By Jeff Floyd Odessa American

One problem with growing tomatoes in heat like ours is a strong desire to give the plant a drink, even though it may have plenty of water available in the soil.

When overwatering overlaps with poor airflow, tomato plants may develop a fungal disease called leaf mold.

Leaf mold fungus (Cladosporium fulvum) usually appears as blotches on the lower leaves where air movement is low and humidity is high.

At first, the upper surfaces of older leaves display a diffuse mottling followed by a fast spreading network of patches that eventually turn yellow and develop a felt-like covering of grayish spores. Warm temperatures and foliage that remains wet for a long time increase the likelihood of leaf mold. Once spores develop, the disease rapidly worsens with the fruit and stems potentially affected as well.

Although the disease favors warm weather, temperatures above ninety-five coupled with low humidity will reduce its prevalence. Increasing the airflow within the canopy will help reduce the humidity within the canopy of the tomato plant and help dry out the fungus. Airflow can be improved by avoiding planting tomatoes too close to one another.

Purchasing healthy transplants at the nursery is the first step in having a good tomato harvest. Sprayed weekly or every ten days, fungicides labeled for leaf mold may help reduce the spread but will not eliminate the disease. Crop rotation also reduces the likelihood of tomatoes getting leaf mold. Rotating crops in a way that ensures no single family of vegetables is planted in the same location more often than every third year effectively solves several garden problems.

To learn more about having a successful tomato harvest this year, contact the Texas A&M AgriLife Extension office at 498-4071 or email jeff.floyd@ag.tamu.edu.

Posted in Gardening on Sunday, June 18, 2017 3:00 am. | Tags: Texas A&m Agrilife Extension Office, Jeff Floyd, Pecans, Pruning, Prune, Soft Landscape Materials, Landscape, Gardening, Gardener, Food, Integra, Repeat Applications, West Texas

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GARDENING: High humidity, poor airflow could rot your tomatoes - Odessa American

Sailors assigned to the Oliver Hazard Perry-class frigate USS Elrod (FFG-55) pose for a photo in front of the ship before her decommissioning ceremony at Naval Station Norfolk in 2015. US Navy Photo

WASHINGTON, D.C. While all options are on the table in the Navys push to field a 355-ship fleet, when it comes toreactivating ships in the inactive fleet, the service is realistically only looking at seven decommissioned Oliver Hazard Perry-class frigates (FFG-7), Chief of Naval Operations Adm. John Richardson told USNI News on Thursday.

Since the December reveal of the Navys new fleet size goal, calls have come from some analysts to reactivate three older Ticonderoga-class cruisers (CG-47) that have been sidelined for more than a dozen years or the conventionally powered Kitty Hawk (CV-63) aircraft carrier.

In the 1980s, the service reactivated ships from the inactive fleet as part of the Reagan Administrations drive to a 600-ship Navy most notably the four Iowa-class battleships (BB-61) from World War II.

The Navy has about 50 warships in the inactive fleet, but so far only the Perrys are seriously being studied for reactivation, Richardson said following a hearing of the Senate Armed Services Committee. He first mentioned the possibility of reactivating Perrys earlier this week during a presentation at the Naval War College.

Bringing those back were examining it and we dont want to overlook any options, but really on the face of it its going to be very complicated, he said. As a ship class comes to the end of its life, its not like were pouring a lot of money into keeping that class modernized. Although the last of the frigates were decommissioned a couple of years ago, weve really stopped modernizing far before that because we just wanted to bring it to a graceful end and there were better places to spend our money at the time.

Rather, the Navy is looking at what it could do now to extend the life of the Arleigh Burke-class guided-missile destroyers (DDG-51) past an expected service life of 35 years, in a more realistic bid to keep up the fleet size.

The DDG life extension plan would prompt a reexamination of key decisions the Navy has made over the last few years on the mid-life modernization of the Burke class.

The Navy elected not to modernize the Aegis Combat Systems of some of the earlier Burkes as a cost-savings measure and instead just executed hull, mechanical and engineering upgrades.

The Baseline 9 combat system upgrade replaces the 1980s-era computer infrastructure of the combat system with faster and more easily upgraded commercial servers, an additional signal processor that allows the ship to fight both traditional air and ballistic missile threats, and a networking capability that allows data to flow from the upgraded destroyer to other ships and aircraft.

How extensively the Navy will take a second look at the DDG upgrade schedule or combat system modernization plan is also being evaluated, Richardson said.

Its the same cost-benefit tradeoff [as the frigates]. You take a look at how much more life might we get, and if its a significant period of time then it might be worth investing in the combat system to modernize and well take it from there, he said. Everything has to be on the table, and I want to understand the entire decision space and that entire landscape.

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CNO Richardson: Perry Frigates Only Inactive Hulls Navy ... - USNI News

Good performance requires good long-term planning. For federal agencies like the National Nuclear Security Administration (NNSA), one of its important functions is preparing its part of the federal governments annual budget request, which normally includes information on projected budget requirements for future years. This year, not so much.

This is important because the Congress, which has final say on what the government funds, needs to know which programs will require increased funding in the following years. Those numbers give Congress and the public a sense of priorities and long-term planning that informs the annual federal budget process.

For the NNSA, those long-term budget numbers are called the Future-Years Nuclear Security Program, or FYNSP (commonly pronounced fin-sip), and they are so important that they are, in fact, required by Congress. In a typical budget request, the budget numbers are simply listed as Outyears and they are provided both by locationeach NNSA facility, including the three nuclear weapons labsand for each program area and project.

I assume this isnt why the budget numbers are missing . . .

However, for almost the entire FY 2018 request, the NNSA budget does not provide future year numbers. In particular, for the Weapons Activities programs (as we discussed in The Bad, the FY 2018 requests were substantially more than the Obama administration projected in their FYNSP) there are no such projections at all in this budget. For example, we dont know how much the NNSA thinks the B61 life extension program will cost in FY 2019-FY2022. That is information that the Congress should have.

(To be fair to the NNSA, the Department of Defense, where the budgets are far, far larger, also did not include outyear budget projections.)

The NNSA FY2018 budget offers an explanation for why there are no outyear budget figures:

Estimates for the FY 2019 FY 2023 base budget topline for the National Nuclear Security Administration reflect FY 2018 levels inflated by 2.1 percent annually. This outyear topline does not reflect a policy judgement. Instead, the Administration will make a policy judgement on amounts for the National Nuclear Security Administrations FY 2019 FY 2023 topline in the FY 2019 Budget, in accordance with the National Security Strategy and Nuclear Posture Review that are currently under development.

So, the budget doesnt have projections because the NNSA is awaiting the results of the Pentagon-led Nuclear Posture Review and the Congressionally-mandated National Security Strategy that the Trump administration is conducting.

Frankly, that explanation is not satisfactory. There is almost no chance that the Nuclear Posture Review will decide to abandon most of the programs designed to maintain and improve the weapons in the US nuclear arsenal. And significant changes to the programs that are already underway (updates to the B61, W88, and W76) are highly unlikely because such modifications would inevitably lead to delays that the Pentagon and the NNSA would not support. For example, as mentioned in The Bad, NNSA officials have said any delays would affect certification requirements for the B61.

The only exception is the life extension program for the W80, which is intended for use on the proposed new nuclear-armed cruise missile, the Long-Range Standoff weapon, or LRSO. Secretary of Defense Mattis has testified that he is not yet convinced of the case for the LRSO, so there is a possibility that the program could be cancelled. (And it should be.) But even so, the NNSA should be planning as if it will not be, as the adverse impact of cancellation is significantly less than the consequences of undertaking required budget work on a weapon that is later cancelled.

For comparison, the Obama administration faced a similar situation when it came to office in 2009. Like the Trump administration, the first budget request, for FY2010, was delivered to Congress later than normal, in May rather than February. The Obama administration was also, like the Trump administration, doing a Nuclear Posture Review and a National Security Strategy. There was also a change in the political party of the President, so one might expect more substantive changes in nuclear weapons policy than if there was continuity in the White House.

Despite those similarities, the Obama administration delivered a FY2010 budget request that included projections for future years. To be fair, the Obama budget also stated that the projections for Weapons Activities were only a continuation of current capabilities, pending upcoming strategic nuclear policy decisions. But the budget actually included additional money for a study of the B61 life extension program, along with further increases in later years.

Moreover, the status of Weapons Activities was dramatically different in 2010 than it is now. In 2010, the W76 was the only active life extension program, and it was already in full production. The B61 was still in study phase, and there was no other active work being done on weapons in the stockpile.

Now, in 2017, the NNSA is involved in four major warhead projects simultaneously, three of which are ramping up substantially. The idea that the NNSA is putting the planning efforts for future work on these programs essentially on hold for a year is troubling.

I suspect one important factor leading to the missing future year budgets is the lack of people in place to do the planning. The man in charge of the NNSA is Lt. Gen. Frank Klotz (Air Force, retired), who by all accounts has done an able job running the agency. He is a holdover from the Obama era, and he was not asked by the Trump team to stay on until the very last day of the Obama administration (which he dutifully did). But no other officials have been nominated for any slots, leaving key positions like the deputy administrator empty while other slots have officials serving only in an acting capacity.

One small thing flagged but not described in The Good is the level of increases the Trump administration claims for its NNSA budgets compared to the Obama teams budgets. The Trump budget claims an 11% increase for the NNSA overall, and even higher increases in Weapons Activitiesaround 15%where the work on nuclear weapons is funded.

But those increases are in comparison to the final FY2016 budget, not the FY2017 budget. Notably, the FY2018 request only lists the FY2017 numbers that were in place under the Continuing Resolution (CR) that operated for a good portion of the year.

But in fact Congress did pass a final appropriations bill, albeit very far into the 2017 fiscal year, and for the NNSA those numbers were significantly higher than under the CR. If you compare the Trump budget to those figures, the NNSA budget receives an increase of 7%, not 11%, and the budget increase for Weapons Activities is 11%, not 15%.

Make no mistake, those are still substantial increases (though as mentioned in The Good they are not dramatically more than increases the Obama administration requested and got Congress to support).

But its worth noting that the Trump budget was presented in a way that makes it look like it has increased NNSA funding more than it actually has.

Posted in: Nuclear Weapons Tags: budget, nuclear posture review, nuclear weapons, nuclear weapons budget, obama administration

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The Case of the Missing Numbers - All Things Nuclear

June 14, 2017 07:00 ET | Source: Amunix Operating Inc

MOUNTAIN VIEW, Calif., June 14, 2017 (GLOBE NEWSWIRE) -- Amunix Operating Inc. is pleased to announce that the U.S. Food and Drug Administration (FDA) has accepted Bioverativs (NASDAQ:BIVV) Investigational New Drug (IND) application for BIVV001 (also known as rFVIII Fc-VWF-XTEN) a novel, investigational Factor VIII therapy designed to potentially extend protection from bleeding episodes via prophylactic once-weekly dosing or longer for patients with hemophilia A.

BIVV001 is the only investigational Factor VIII therapy in development that has been designed to overcome the von Willebrand factor ceiling, which is believed to impose a half-life limitation on current Factor VIII therapies.

We are very pleased by the announcement from Bioverativ that clinical enrollment is planned to begin in the latter half of 2017. This represents the second clinical trial involving an XTEN-based product to be initiated this year, remarked Volker Schellenberger, CEO and President of Amunix. We look forward to the evaluation of BIVV001 in the clinic and the continued progression of Bioverativs hemophilia programs that exploit the advantages offered by the XTEN technology platform.

About Amunix:

Amunix, based in Mountain View, CA, is a privately held biotechnology company focused on the discovery and development of biologics with improved in vivo half-lives. Amunix half-life extension technology is based on XTEN hydrophilic, unstructured, biodegradable proteins that impart a number of favorable properties upon the molecules to which they are attached. XTEN can be recombinantly fused or chemically conjugated to peptides, proteins, and other pharmaceuticals. In addition to the advantages of reduced dosing frequency, XTENylation also stabilizes plasma drug concentrations, which often results in increased efficacy as well as reduced side effects. Two genetically fused XTENylated products have been tested clinically. VRS-859 (exenatide-XTEN) has been tested through Phase I in the treatment of diabetes and VRS-317 (human growth hormone-XTEN) is currently in Phase III testing. Amunix is also working with additional partners, including Eli Lilly, Bioverativ, Roche, Janssen, Genentech, Naia and other undisclosed companies in a wide range of therapeutic areas.

Amunix is developing an internal pipeline of ProTIA (Protease Triggered Immune Activator) immuno-oncology therapeutics. ProTIAs are bispecific molecules that bind tumor antigens and T cells. ProTIAs are administered as long-acting prodrugs that can be activated in the tumor environment by tumor-associated proteases. Amunix is actively seeking partnerships for applications of its XTEN technology and its ProTIA platform. For additional information about the company, please visit http://www.amunix.com.

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Bioverativ announces FDA acceptance of Investigational New Drug ... - GlobeNewswire (press release)

The strawberries are ripe! If you have a home garden or community garden plot, you may already be harvesting fruits and vegetables for your table. If you dont, you can take advantage of one of the many u-pick farms in Douglas County. If you want to preserve some of your harvest to enjoy later in the year, here are a few reminders to make sure you have a safe, high quality product.

Take stock of what you have in the pantry or freezer from last year.

Before you start adding new items to your freezer, or make another batch of strawberry jam, think about what you actually use in a year. For best quality, most canned foods should be used within a year. However, they will still be safe if the seal is intact, they were canned using proper methods and they havent been exposed to extreme hot or cold temperatures.

Frozen foods kept in a freezer at 0F or below maintain quality for a few months to a year, depending on the product. Longer storage times will affect the quality but not the safety if they are handled properly.

Check your recipes.

Make sure you are using up-to-date, research-based information for all of your food preservation activities. Recommendations and recipes have changed over the years, and there is a lot of untested information available on the internet.

OSU Extension has dozens of publications available on its website, covering everything from low-sugar fruit spreads to canning smoked fish: http://extension.oregonstate.edu/fch/food-preservation.

Other reliable sources of information include So Easy to Preserve from the University of Georgia Cooperative Extension, the Ball Blue Book Guide to Preserving and the USDA Complete Guide to Home Canning. If you dont have access to the internet, stop by the Extension Office to pick up a copy of current publications.

OSU Extension also has a new app available for Android and iOS users. Intended for people with previous canning experience, the app provides simple checklists and a built-in timer to guide users in canning vegetables, fruits, meats and fish. https://catalog.extension.oregonstate.edu/pnw689

Take a food preservation class to learn a new skill or refresh your memory.

Master Food Preservers offer hands-on classes for a minimal fee throughout the summer and fall. Upcoming classes include: Jams, Jellies and Pie Filling noon to 3 p.m. on June 24 at the Sutherlin Community Center, Pressure Canning Tuna 10 a.m. to 4 p.m. on July 29 at the Umpqua Community Center and Canning Tomatoes and Salsa 9 a.m. to 12 p.m. on Aug. 26 at Pine Grove Community Church.

For more complete class information, and to register, visit http://extension.oregonstate.edu/douglas/food or contact the Douglas County OSU Extension Office at 541-672-4461.

Have the gauge tested on your pressure canner.

If you are pressure canning low-acid foods like tuna or green beans, it is essential that your gauge be accurate. All new pressure canner gauges should be tested before use, and then annually or when the lid has been dropped or bumped. OSU Extension Service Master Food Preserver volunteers are available to answer food preservation questions and test pressure canner gauges for free at the following locations.

Douglas County OSU Extension Service (office)

1134 SE Douglas Avenue, Roseburg.

1st & 3rd Thursdays of the month, July through October

10 a.m. to 2 p.m.

Douglas County Farmers Co-op, 124 SW Douglas Ave., Winston

1st and 3rd Sundays, June through August

10 a.m. to 1 p.m.

Lehne Garden & Orchard

386 Cleveland Rapids Road, Roseburg (off Garden Valley Road)

Saturdays, July 15 through Sept. 30, and alternating Fridays, July 14 through Sept. 29

10 a.m. to 2 p.m.

Umpqua Valley Farmers Market

1771 W. Harvard, Roseburg (First United Methodist Church parking lot)

Saturdays, June 3 through Sept. 30

9 a.m. to 1 p.m.

Elkton Community Education Center

15850 State Hwy 38 West, Elkton, OR

July 11, Aug. 8 and Sept. 12

9 a.m. to 11 a.m.

If you find yourself in a pickle and still have questions, call the OSU Food Safety and Preservation Hotline at 1-800-354-7319.

The hotline is available 9 a.m. to 4 p.m. Monday through Friday July 10 through Oct. 13. It is staffed by trained Master Food Preserver volunteers from Douglas and Lane Counties.

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Extension Spotlight: Are you ready to preserve the harvest? | Life ... - NRToday.com

BBC News

Charlie Gard: European Court orders life support extension BBC News The parents of a terminally-ill baby have been given more time to put forward a legal case that he should be allowed to go to the US for treatment. Life-support for Charlie Gard must continue until midnight on Monday, the European Court of Human Rights ... Charlie Gard to be kept on life support while European judges consider caseThe Guardian all 94 news articles »

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Charlie Gard: European Court orders life support extension - BBC News

June 12, 2017 09:00 ET | Source: ProLynx LLC

SAN FRANCISCO, June 12, 2017 (GLOBE NEWSWIRE) -- In a late-breaking abstract at the 77th American Diabetes Association meeting in San Diego, ProLynx LLC announced a novel drug delivery system to support once-monthly subcutaneous (SC) administration of a GLP-1 receptor agonist (GLP-1RA) called PLX039 for the treatment of Type 2 diabetes (T2D). The work will be published in ACS Chemical Biology.

GLP-1RAs have emerged as an important standard-of-care drug class for the treatment of Type 2 diabetes and are projected to command a $12 Bill market by 2024. These agonists auto-regulate blood glucose concentration, have anti-obesity effects, and may reduce risks for adverse cardiovascular events in patients with T2D. Currently, there are three once- or twice- daily and three once-weekly GLP-1RAs approved by the FDA; an additional once-weekly agonist and a long-acting osmotic pump delivery system are in late stage trials. Yet, poor medication adherence and persistence remain as major factors leading to failure of glycemic control in almost 50% of T2D patients. Now, ProLynx has used its half-life extension platform to develop a monthly-administered GLP-1RA. Compared to weekly-administered agonists, obvious benefits are believed to include greater patient convenience, compliance and persistence.

Daniel Santi, co-founder and President of ProLynx, said: This is the first GLP-1RA that does not require huge doses of a drug meant for weekly administration to maintain therapeutic levels over a monthly period. Santi added: PLX039 should find a dose-interval sweet-spot with its once-monthly administration. Some patients will find that a once-weekly dosing interval is too short, and will not want to have a long-acting osmotic pump implanted; for these patients, the once monthly GLP-1 receptor agonist PLX039 should be just right.

In the ProLynx half-life extension platform, a drug is tethered to hydrogel microspheres by a self-cleaving linker that is pre-programmed to release the drug at a pre-determined rate. After SC injection, the drug is slowly released from the microsphere depot into the systemic circulation. ProLynx attached their peptidic GLP-1RA a stabilized analog of exenatide to its hydrogel microspheres. After SC injection to rodents the GLP-1RA showed a serum half-life of one month. Monthly injections of the formulation in diabetic rats showed identical glucoregulatory effects as continuously infused exenatide, and simulation of the pharmacokinetics indicate it should serve well as a once-a-month treatment for T2D in humans.

About ProLynx. ProLynx LLC is a privately held biotechnology company developing proprietary drug delivery systems for half-life extension of proteins, peptides and small molecules. The company is seeking to apply its technology to extend half-lives of drug candidates of pharmaceutical companies, and to improve properties of off-patent therapeutics. ProLynx has a monthly GLP-1 receptor agonist and a subcutaneous long-acting octreotide in its pre-clinical portfolio, and a PEG~SN-38 in Phase 1 clinical trials. The company is located in San Francisco, CA. Further information about the company may be found at http://www.ProLynxllc.com.

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ProLynx announces PLX039, a hydrogel-microsphere drug delivery ... - GlobeNewswire (press release)