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Category Archives: Corona Virus

Older US adults should get another COVID-19 shot, advisers say – NBC Bay Area

Posted: February 29, 2024 at 11:14 pm

L.L. Bean has just added a third shift at its factory in Brunswick, Maine, in an attempt to keep up with demand for its iconic boot.

Orders have quadrupled in the past few years as the boots have become more popular among a younger, more urban crowd.

The company says it saw the trend coming and tried to prepare, but orders outpaced projections. They expect to sell 450,000 pairs of boots in 2014.

People hoping to have the boots in time for Christmas are likely going to be disappointed. The bootsare back ordered through February and even March.

"I've been told it's a good problem to have but I"m disappointed that customers not getting what they want as quickly as they want," said Senior Manufacturing Manager Royce Haines.

Customers like, Mary Clifford, tried to order boots on line, but they were back ordered until January.

"I was very surprised this is what they are known for and at Christmas time you can't get them when you need them," said Clifford.

People who do have boots are trying to capitalize on the shortage and are selling them on Ebay at a much higher cost.

L.L. Bean says it has hired dozens of new boot makers, but it takes up to six months to train someone to make a boot.

The company has also spent a million dollars on new equipment to try and keep pace with demand.

Some customers are having luck at the retail stores. They have a separate inventory, and while sizes are limited, those stores have boots on the shelves.

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Cognitive Deficits Seen in COVID-19 Patients Regardless of Symptom Duration – HealthDay

Posted: at 11:14 pm

THURSDAY, Feb. 29, 2024 (HealthDay News) -- Similar small cognitive deficits are seen for individuals who recovered from COVID-19 in whom symptoms had resolved in less than four weeks or at least 12 weeks, according to a study published in the Feb. 29 issue of the New England Journal of Medicine.

Adam Hampshire, Ph.D., from Imperial College London, and colleagues estimated a global cognitive score across eight tasks in 112,964 participants who completed an online cognitive assessment.

The researchers found that compared with individuals in the no-COVID-19 group who had not been infected with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) or had unconfirmed infection, participants who recovered from COVID-19 in whom symptoms had resolved in less than four weeks or at least 12 weeks had similar small deficits in global cognition (0.23 and 0.24 standard deviation [SD], respectively), while larger deficits were seen for those with unresolved persistent symptoms (0.42 SD). Participants who had SARS-CoV-2 infection during periods in which the original virus or the B.1.1.7 variant was predominant had larger deficits than those infected with later variants; deficits were also larger for those who had versus had not been hospitalized. These results were similar to those of propensity score-matched analyses. Memory, reasoning, and executive function tasks were associated with the largest deficit in comparison of the group with unresolved persistent symptoms versus the no-COVID-19 group.

"We found objectively measurable cognitive deficits that may persist for a year or more after COVID-19," the authors write. "The implications of longer-term persistence of cognitive deficits and their clinical relevance remain unclear and warrant ongoing surveillance."

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CDC recommends seniors get another Covid-19 shot – Baltimore Sun

Posted: at 11:14 pm

(CNN) People age 65 and older should get an additional dose of the current Covid-19 vaccine, the US Centers for Disease Control and Prevention recommends.

The agencys independent vaccine advisers voted Wednesday to recommend the additional shot, and CDC Director Dr. Mandy Cohen endorsed the recommendation.

The vote of CDCs Advisory Committee on Immunization Practices was 11 yes and one no, with one person abstaining.

Under the new recommendation, people 65 and older can receive an additional dose of any updated Covid-19 vaccine at least four months after the previous shot.

The current Covid-19 vaccine, which was updated last fall, is considered highly effective. Early estimates from CDC studies show that although there has been no substantial waning yet, protection will wane over time. However, the protection offered by any vaccine disappears even quicker in older people because their immune systems dont respond as well.

The initial proposal used the word may, but the committee changed the language to should to emphasize how important it is to get vaccinated against Covid-19.

Although 98% of the US population has some kind of immunity to Covid-19, whether from infection, vaccination or both, that gives only some protection against infection or severe disease, CDC epidemiologist Dr. Ruth Link-Gelles told the advisers during Wednesdays meeting.

It doesnt protect absolutely, she said.

What the vaccines are doing now is providing an incremental benefit or an extra benefit beyond whatever benefit someone has remaining from their past infection or past vaccination, and we know that protection from past vaccination and past infection wanes, Link-Gelles said. Thats important for all people in the United States but especially important for those that are the highest risk.

Data from the CDC shows that throughout the pandemic, older adults have been the most vulnerable to the severe effects of Covid-19.

Covid-related hospitalizations for adults 65 and older have been consistently higher than for all other age groups. About two-thirds of Covid hospitalizations are people in this age group, CDC data shows. Seniors also make up the greatest proportion of those who died in a hospital with Covid and have the highest numbers of deaths even after theyve been discharged.

Of older adults hospitalized with Covid, the highest percentage had no record of any vaccination against the coronavirus since the original shot, according to data from last fall that was presented to the committee Wednesday.

The vaccine is recommended for everyone ages 6 months and older, but data from the CDC shows that people havent been getting the shots.

Strong evidence from new research shows that the vaccine can not only prevent severe disease but may cut the chances of getting a symptomatic infection by half, including against JN.1, the most common circulating variant of the virus. Yet only about 21% of adults and about 12% of children have gotten the vaccine since its update in September, according to the CDC. By comparison, nearly half of adults and kids in the US have gotten a flu vaccine this season.

The National Immunization Survey shows that most Americans still consider Covid-19 vaccines to be safe and important, but peoples confidence in the vaccine has fallen from 83.9% in January 2022 to 69.6% last month.

Disease risk perception has also changed, according to the survey, and fewer adults say they are moderately or very concerned about getting Covid. Despite the general perception, Covid is still very much a threat, particularly to vulnerable populations like older people and those with underlying conditions.

There were about 20,000 new hospital admissions and 2,000 Covid-19 deaths a week as of the week ending February 17, CDC representatives told the advisory committee. Even when numbers were at their lowest last summer, there were still about 500 Covid-19 deaths per week.

Part of the problem may be that doctors arent always advising their patients to get a Covid shot. The National Immunization Survey shows that in January, relative to 2021, fewer people said their providers encouraged them to get the vaccine.

It is shocking to see that 30% to 40% of the higher-risk populations at least for elderly, and I think its a similar number for immunocompromised are getting the updated vaccine, said advisory committee member Dr. Camille Kotton, clinical director of transplant and immunocompromised host infectious diseases at Massachusetts General Hospital.

Kotton thinks Americans have been confused about whether they should get the vaccine and thinks health leaders need to be clearer about the recommendations.

For me, this is a life and death situation for many of the patients that I take care of, she said.

The-CNN-Wire & 2024 Cable News Network, Inc., a Warner Bros. Discovery Company. All rights reserved.

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Odds of Severe COVID-19 High for Hematologic Cancer Patients During Pandemic – HealthDay

Posted: at 11:14 pm

THURSDAY, Feb. 29, 2024 (HealthDay News) -- For patients with hematologic cancers, the odds of developing severe COVID-19 despite vaccination remained high through mid-2022, according to a study published online Feb. 23 in JAMA Network Open.

Sonia T. Anand, Ph.D., M.P.H., from the VA Boston Cooperative Studies Program, and colleagues conducted a case-control study including all patients with hematologic malignant neoplasms in the national Veterans Health Administration with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection after vaccination. Patients with severe COVID-19 (cases) versus nonsevere COVID-19 (controls) were compared; data were included for 6,122 patients, 21.3 percent of whom had severe COVID-19.

The researchers found that the odds of severe disease were higher in association with age (adjusted odds ratio [aOR] per one-year increase, 1.05), treatment with antineoplastic or immune-suppressive drugs (e.g., in combination with glucocorticoids: aOR, 2.32), and comorbidities (aOR per comorbidity, 1.35). Booster vaccination was associated with lower odds of severe disease. Overall, 3.7 percent of patients with SARS-CoV-2 infection during the period after oral antiviral drugs became widely used in March 2022 had progression to severe COVID-19.

"Although the magnitude of benefit of antiviral treatments during nonsevere disease could not be quantified, the relatively low proportion of treated patients who developed severe COVID-19 is sufficient to promote greater use," the authors write.

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COVID-19 may have small but lasting effects on cognition and memory | Imperial News – Imperial College London

Posted: at 11:14 pm

COVID-19 may have an impact on peoples cognitive and memory abilities that lasts a year or more after infection.

A new study by Imperial College London researchers reveals small deficits in the performance of cognitive and memory tasks in people who had recovered from COVID-19 compared with those who had not had COVID-19.

This includes people who had long duration symptoms (i.e., Long COVID) that had eventually resolved.

The study also shows that the cognitive deficits were larger for people who were hospitalised, who had ongoing long duration symptoms, or who were infected with earlier variants of the virus.

The study is published today in the New England Journal of Medicine.

The Imperial-led study, called REACT Long COVID, enrolled more than 140,000 participants, who undertook at least one cognitive task, with many having experienced COVID-19 at various levels of severity and persistence.

Participants in the study were asked to perform an innovative online cognitive assessment on the Cognitron platform, which comprises tasks that can detect subtle changes in different aspects of their brain function, such as memory, reasoning, executive function, attention and impulsivity.

The large scale of the study and the sensitivity of the computerised tests allowed factors that explained cognitive deficits post-COVID to be examined in very fine detail while controlling for population variables such as age, demographics and pre-existing medical conditions.

The study revealed small deficits that were still detectable a year or more after infection, even in people who had short duration illness. They were larger for people who had symptoms lasting 12 weeks or more (consistent with Long COVID), those who had been to hospital for their illness or those who were infected with one of the early variants of the SARS-CoV-2 virus.

However, people who had longer lasting symptoms that had resolved by the time they did the cognitive assessment showed small deficits that were similar in size to those of people who had a shorter duration illness.

The results showed that COVID-19 was associated with deficits in multiple areas of cognition, most notably in memory, such as the ability to remember pictures of objects that were viewed a few minutes earlier. The researchers believe this may be due to problems forming new memories rather than accelerated forgetting.

People also showed small deficits in some tasks testing executive and reasoning abilities, such as those that require spatial planning or verbal reasoning.

First author of the study Professor Adam Hampshire, from the Department of Brain Sciences at Imperial College London, said: The potential long-term effects of COVID-19 on cognitive function have been a concern for the public, healthcare professionals, and policymakers, but until now it has been difficult to objectively measure them in a large population sample.

By using our online platform to measure multiple aspects of cognition and memory at large scale, we were able to detect small but measurable deficits in cognitive task performance. We also found that people were likely affected in different ways depending on factors such as illness duration, virus variant and hospitalisation.

Professor Paul Elliott, senior author and Director of the REACT programme, from the School of Public Health at Imperial College London, said: It is reassuring that people with persistent symptoms after COVID-19, that had resolved, may expect to experience some improvement in their cognitive functions to similar levels as those who experienced short illness.

Furthermore, the cognitive impact of COVID-19 appears to have reduced since the early stages of the pandemic, with fewer people having persistent illness, and cognition being less affected amongst those that were infected during the time when Omicron was the dominant strain. However, given the large numbers of people who were infected, it will be important to continue to monitor the long-term clinical and cognitive consequences of the COVID-19 pandemic.

Cognition and memory after COVID-19 in a large community sample by Hampshire, A., et al is published in NEJM. DOI:https://doi.org/10.1056/NEJMoa2311330

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More free home COVID-19 tests available from US government – WCVB Boston

Posted: November 20, 2023 at 7:41 pm

FROM SELLING TOBACCO, RESTOCKING YOUR SUPPLY OF COVID 19 TESTS BEGINNING ON MONDAY, HOUSEHOLDS HERE CAN ORDER FOR FREE KITS THROUGH A FEDERAL WEBSITE HERE I MEAN IN THE UNITED STATES. HERE TO ANSWER QUESTIONS, DR. KRISTIN MOFFAT, AN INFECTIOUS DISEASE SPECIALIST AT BOSTON CHILDRENS HOSPITAL, GREAT TO SEE YOU, DOCTOR. GOOD TO SEE YOU, TOO. YEAH. HI, DR. MOFFAT. YOU KNOW, ITS BEEN A LONG TIME SINCE SOME OF US HAVE EVEN LOOKED AT OUR STOCKPILE OF TESTS AT HOME. RIGHT. PROBABLY IN THE CLOSET. WHAT ARE THE CHANCES THAT THEYRE ALL EXPIRED? YEAH, ITS A REALLY GOOD POINT TO BRING UP. IT IS POSSIBLE THAT THEY ARE EXPIRED, SO EVERYBODY SHOULD CHECK THE EXPIRATION DATE ON THEIR COVID TESTS. BUT DONT THROW THEM OUT IF YOU SEE THAT THE DATE SHOWS THAT ITS EXPIRED BECAUSE A LOT OF THESE DIFFERENT BRANDS WERE DOING SORT OF POST DISTRIBUTION TESTING TO SEE IF THEY WERE STILL EFFECTIVE BEYOND THE EXPIRATION DATES. AND INDEED, A LOT OF THESE EXPIRATION DATES HAVE BEEN EXTENDED BY SOMEWHERE BETWEEN 6 AND 10 MONTHS. SO THERE IS AN FDA WEBSITE THAT LISTS THESE EXPIRATION DATE EXTENSIONS BY BRAND. SO I WOULD DEFINITELY RECOMMEND CHECKING THAT OUT BEFORE YOU TOSS ANY TESTS. I ACTUALLY DID THAT AND THEYRE ALL EXPIRED. SO THATS THAT IS ITS GREAT ADVICE. SO LETS TALK ABOUT THESE NEW ROUNDS OF FREE TESTS THE WEBSITE TO ORDER THEM COVID TESTS.GOV. IT OPENS ON MONDAY. WHY WHY IS THIS BEING OFFERED NOW? YEAH, I THINK ITS GREAT THAT THIS IS BEING OFFERED. AGAIN, IF YOU MAY REMEMBER, THERE WAS A TIME WHEN INSURANCE DID COVER THIS OR THESE WERE BEING OFFERED AT NO COST AND THEYRE EXPENSIVE. WHEN WE GO AND BUY THESE OUT OF POCKET DRUGSTORE, THEYRE NOT CHEAP CASES ARE RISING RIGHT NOW. HOSPITALIZATIONS HAVE BEEN RISING. AND ITS CONCEIVABLE IN THE COMING MONTHS AS PEOPLE SPEND MORE TIME TOGETHER INDOORS WITH HOLIDAYS COMING UP TOGETHER IN THE COMING MONTHS, TRANSMISSION COULD INCREASE EVEN MORE. AND IT REMAINS TRUE THAT TESTING FOR COVID, IF YOUVE GOT SYMPTOMS OF COVID AND ISOLATING IF YOURE POSITIVE, IS A REALLY IMPORTANT PART OF KEEPING ANOTHER SURGE FROM HAPPENING. SO I THINK ITS A GREAT MOVE TO MAKE THESE AVAILABLE AGAIN, AT NO COST SO THAT EVERYBODY WHO WANTS THEM HAS ACCESS TO THEM. I THINK ITS ALSO IMPORTANT TO REMEMBER THAT WEVE GOT TREATMENTS AVAILABLE NOW LIKE PAXLOVID, THAT WE DIDNT HAVE AVAILABLE A COUPLE OF YEARS AGO AND TREATMENTS LIKE THAT ARE MOST EFFECTIVE IF THEYRE STARTED AS SOON AS SOMEBODY KNOWS THAT THEY HAVE AN INFECTION DUE TO COVID. SO BEING ABLE TO HAVE TESTS AT HOME AND CONFIRM THAT YOUR SYMPTOMS ARE DUE TO COVID, ITS REALLY HELPFUL IN A LOT OF WAYS. OKAY. AND OF COURSE, THE VIRUS, YOU KNOW, ALWAYS KEEPS CHANGING BECAUSE THATS WHAT VIRUSES DO. THIS ONE HAS CHANGED A LOT OVER THE YEARS. ANY CONCERNS ABOUT NEW VARIANTS DOWN THE ROAD OR TESTING OF ANY OF THAT? YEAH, ITS A GREAT QUESTION. IT ALWAYS WOULD BE OF CONCERN. WE WANT TO MAKE SURE THE TESTS WE HAVE, IF THEYRE NEGATIVE, CAN WE TRUST THEM? AND THIS IS SOMETHING THAT THE FDA AND OTHER AGENCIES ARE REGULARLY AND SYSTEMATICALLY DOING FOR ALL OF THE AUTHORIZED TESTS. THERE HAVE BEEN SOME INSTANCES OF TESTS THAT ARE NOT THE ONES AS BROADLY AVAILABLE WHERE THEIR PERFORMANCE HAS BEEN DECREASED WITH SOME OF THE VARIANTS. BUT ITS REALLY IMPORTANT THAT THIS CONTINUES TO BE MONITORED. FOR THE MOST PART, THE ONES THAT REMAIN BROADLY AVAILABLE HAVE NOT EXHIBITED ANY DECREASED PERFORMANCE WITH VARIANTS THAT HAVE EMERGED OVER THE LAST COUPLE OF YEARS. BUT THIS IS SOMETHING THAT NEEDS TO CONTINUE TO BE EVALUATED. ALL RIGHT, DR. MOFFITT, THANK YOU SO MUCH FOR SPENDING SOME TIME WITH US.

More free home COVID-19 tests available for order from US government

Updated: 2:15 PM EST Nov 20, 2023

U.S. households are now eligible to order an additional four at-home COVID-19 tests free of cost through the government.As of Monday, residential households in the U.S. can submit an order through Covidtests.gov for four individual rapid antigen COVID-19 tests. Orders will start to ship on Nov. 27, according to USPS. People without an internet connection can call 1-800-232-0233 (TTY 1-888-720-7489) to request tests.The U.S. government had suspended the rapid test distribution program earlier in May, then reopened it in September. Residents who havent placed an order since the program reopened can place two orders, which will provide eight tests in total, according to USPS.COVID-19 rapid tests can be taken at home and can be used regardless of whether someone has symptoms. The tests should work through the end of the year; some of the dates on the tests may show that they are expired, but the U.S. Food and Drug Administration has extended those dates.The U.S. Centers for Disease Control and Prevention recommends people test if they have any COVID-19-like symptoms including a sore throat, runny nose, loss of smell or taste, or a fever. People may also want to test before they are going to be a part of a large event, like a concert or a conference, particularly if people are not up-to-date on their vaccines. Antivirals are available to treat COVID-19 and flu, and testing can help determine which medication is needed.COVID-19 hospital admissions and emergency department visits are once again on the rise after a few weeks of downturn, according to the CDC. For the week ending Nov. 11, the percentage of COVID-related emergency department visits was 1.4%, or just over 16,200 people similar to rates seen throughout this month and last month.Overall, outpatient visits for flu-like illness are lower than they were at this time last year but higher than in the previous four seasons. CDC forecasting suggests that this respiratory virus season will result in about the same number of hospitalizations as last season.Seasonal flu activity is also increasing in most parts of the country with flu-like activity labeled as high in New Mexico, Florida, Alabama, Mississippi, Georgia and South Carolina, according to the CDC. There have been at least 780,000 illnesses, 8,000 hospitalizations, and 490 deaths from flu so far this season, the agency estimates.More than a third of adults and nearly a third of children have gotten their flu shot this year, CDC data shows. About 14% of adults and 5% of children have gotten the new COVID-19 vaccine while 14% of older adults ages 60 and up have gotten the new RSV vaccine.

U.S. households are now eligible to order an additional four at-home COVID-19 tests free of cost through the government.

As of Monday, residential households in the U.S. can submit an order through Covidtests.gov for four individual rapid antigen COVID-19 tests. Orders will start to ship on Nov. 27, according to USPS. People without an internet connection can call 1-800-232-0233 (TTY 1-888-720-7489) to request tests.

The U.S. government had suspended the rapid test distribution program earlier in May, then reopened it in September. Residents who havent placed an order since the program reopened can place two orders, which will provide eight tests in total, according to USPS.

COVID-19 rapid tests can be taken at home and can be used regardless of whether someone has symptoms. The tests should work through the end of the year; some of the dates on the tests may show that they are expired, but the U.S. Food and Drug Administration has extended those dates.

The U.S. Centers for Disease Control and Prevention recommends people test if they have any COVID-19-like symptoms including a sore throat, runny nose, loss of smell or taste, or a fever. People may also want to test before they are going to be a part of a large event, like a concert or a conference, particularly if people are not up-to-date on their vaccines. Antivirals are available to treat COVID-19 and flu, and testing can help determine which medication is needed.

COVID-19 hospital admissions and emergency department visits are once again on the rise after a few weeks of downturn, according to the CDC. For the week ending Nov. 11, the percentage of COVID-related emergency department visits was 1.4%, or just over 16,200 people similar to rates seen throughout this month and last month.

Overall, outpatient visits for flu-like illness are lower than they were at this time last year but higher than in the previous four seasons. CDC forecasting suggests that this respiratory virus season will result in about the same number of hospitalizations as last season.

Seasonal flu activity is also increasing in most parts of the country with flu-like activity labeled as high in New Mexico, Florida, Alabama, Mississippi, Georgia and South Carolina, according to the CDC. There have been at least 780,000 illnesses, 8,000 hospitalizations, and 490 deaths from flu so far this season, the agency estimates.

More than a third of adults and nearly a third of children have gotten their flu shot this year, CDC data shows. About 14% of adults and 5% of children have gotten the new COVID-19 vaccine while 14% of older adults ages 60 and up have gotten the new RSV vaccine.

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Seniors made up 63 percent of covid hospitalizations earlier this year – The Washington Post

Posted: at 7:41 pm

People 65 and older constituted nearly 63 percent of U.S. hospitalizations for covid-19, with the rate increasing with age, through the first eight months of 2023, according to a report from the Centers for Disease Control and Prevention.

The CDC found that people in that age group also represented more than half of the admissions to intensive care units in that period and nearly 90 percent of deaths among those hospitalized because of covid.

The hospitalization number reflects an increase from preceding months (March 2020 through December 2022), when about 46 percent of those hospitalized because of covid were 65 or older.

The report found that most older people hospitalized from January through August this year had at least one underlying health condition, and most had two or more. Most common were diabetes, kidney disorders, coronary artery disease, heart failure and obesity.

The report also noted that more than 75 percent of older adults who had been hospitalized with covid this year had not gotten the bivalent vaccine, which protects against the original coronavirus as well as subsequent variants and had been recommended last year for everyone 5 and older. This year, everyone 6 months and older is being urged to keep their coronavirus vaccinations up to date because the virus that causes covid-19 changes frequently.

The risk of contracting covid has been shown to increase with age, which has made older people with covid more likely to get very sick, need a ventilator to breathe and require hospitalization, often in an ICU.

Health experts stress that vaccination reduces the odds of hospitalization, long covid (symptoms or conditions that develop or linger after the initial infection) and dying. But it also protects others by limiting spread of the disease.

This article is part of The Posts Big Number series, which takes a brief look at the statistical aspect of health issues. Additional information and relevant research are available through the hyperlinks.

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Fifth Covid-19 wave sees biggest bump in virus detection since … – New Zealand Herald

Posted: at 7:40 pm

New Zealands fifth Covid-19 wave appears to be driving a larger spike in cases than our last bump in April. Photo / 123RF

New Zealands fifth Covid-19 wave appears to be driving the largest spike in infections seen all year, an epidemiologist says - and offers a glimpse of our long-term future with the coronavirus.

Health officials yesterday announced 7881 new reported Covid-19 cases over the week to Sunday, of which 1474 were probable cases that was up from 5947 and 1047 respectively on the week before.

Hospitalisation numbers, too, had ticked upward, from 284 to 349 week-on-week, as had virus detected in wastewater surveillance.

ESR data showed a national average of 5.06 million copies of the virus detected per person, per day in wastewater at November 12 double what was detected just a month before.

Of the indicators that are now the most valid wastewater and hospitalisations both have been at their highest levels since January, if you take their peak values, Otago University epidemiologist Professor Michael Baker said.

Looking at hospitalisations in particular, it seems to be a bigger peak than what we saw in the fourth wave. This may be showing us what we can expect in the long term, which is peaks and troughs.

Modellers still didnt see this wave reaching the height of the one that took off around this time in 2022 - when case numbers reached the mid-8000s and weekly hospitalisations nearly topped 600 as it was growing off a much lower base.

There was also nothing to suggest any game-changing new subvariant was helping build any wave the size of 2022s largest ones, in what was now a highly-exposed and highly-vaccinated population.

The latest ESR sampling showed a mix of Omicron subvariants albeit with the EG.5 or Eris type and its relatives now making up more than half of genomes sequenced - still driving spread.

It remained to be seen whether infection rates would keep rising as Christmas neared - with wastewater detections having taken a slight dip.

It looks like were seeing the wave perhaps peaking in some parts of New Zealand, but rising in others - so theres now a bit of regional variation, Baker said.

But the overall pattern is really clear. Were in a large wave and we need to respond to it.

Longer term, Baker said a national approach was needed to manage these peak periods.

Thats because a lot of people are getting sick, are going to hospital and putting pressure on the system and unfortunately, deaths are going up too.

The 20 further deaths reported from last week added to a total 3522 since the beginning of the pandemic.

We have already invested extensively in all these surveillance systems, so now I think we need to act on the information that theyre giving us.

He singled out several priority areas he felt required addressing, including promoting boosters; supporting to help people self-isolate, and consistent policy for ventilation standards and mask use in healthcare settings.

Last week, Baker and colleagues called on the Government to set up a dedicated centre for disease control like that in the US, and now being established in Australia - to better prepare for future pandemics.

Jamie Morton is a specialist in science and environmental reporting. He joined the Herald in 2011 and writes about everything from conservation and climate change to natural hazards and new technology.

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KFF COVID-19 Vaccine Monitor November 2023: With COVID … – KFF

Posted: at 7:40 pm

Key Takeaways

The latest KFF COVID-19 Vaccine Monitor survey suggests the lack of public concern about getting sick from COVID-19 may be why many people have not gotten the latest vaccine and why half of the public are not planning on taking precautions to limit the spread of the virus during the coming months.

The November KFF COVID-19 Vaccine Monitor investigates uptake for the new, updated COVID-19 vaccine, which has been recommended by the CDC for people ages 6 months and older. Two months after the vaccine became available, about half of adults say they have gotten or will get the shot, but another half say they wont get the latest shot and a third seem steadfast in that decision.

One in five (20%) adults now say they have received the new, updated COVID-19 vaccine that became available in September. An additional one in four adults say they will definitely get (13%) or probably get (15%) the updated shot. Consistent with demographic differences across other COVID-related behaviors, uptake is highest among those ages 65 and older (34%) and Democrats (32%). This is meaningful given that those ages 65 and older are more vulnerable to COVID-19, as theyre more likely to get seriously sick and experience complications that could result in hospitalization. This is in comparison to smaller shares of younger adults ages 18-29 (18%), Republicans (12%) and independents (16%) who report getting the latest vaccine. Similar shares across racial and ethnic groups report having gotten the updated vaccine, including 26% of Black adults, 20% of Hispanic adults, and 19% of White adults. However, when combining the shares who have gotten the shot and those who intend to get it, Black adults (59%) and Hispanic adults (59%) both outpace White adults (42%).

Uptake of the newest vaccine matches closely to uptake of the updated bivalent booster measured in December 2022, just after the updated bivalent COVID-19 booster had become available for use. About two in ten adults said they had received the booster dose (22%).

One in three (34%) adults say they will definitely not get the new COVID-19 vaccine, and another 17% say they will probably not get the vaccine. The share who say they probably or definitely wont get the new COVID-19 vaccination has remained unchanged from the September COVID-19 Vaccine Monitor, which was fielded immediately prior to when the vaccine became available.

Majorities of those who have never received any COVID-19 vaccine (94%), Republicans (77%), independents (59%), those who live in rural areas (65%), White adults (58%), and those under the age of 65 (55%) continue to say they will not get the updated COVID-19 vaccine.

The survey finds that partisanship is continuing to play an outsized role in vaccine attitudes. While nearly six in ten White adults say they do not plan to get the new vaccine, this increases to eight in ten among White adults who self-identify as Republicans. This is more than twice the share of White adults who are Democrats (29%) who say they will either definitely not or probably not get the vaccine. In fact, three in ten (31%) White adults who are Democrats have already gotten the new vaccine, compared to 11% of their Republican counterparts.

Most adults (79%) say they have heard at least a little about the updated COVID-19 vaccine, with one in five (22%) saying they have heard a lot. A small share (21%) say they have heard nothing at all about the updated vaccine.

Awareness is high across demographic groups, including the vast majority (92%) of adults ages 65 and older who have heard at least a little about the updated vaccine compared to a somewhat smaller share, but still a majority, of younger adults, including six in ten of those ages 18 to 29. Larger shares of Democrats are also more aware of the vaccine, with 86% who have heard at least a little compared to three-quarters (74%) of Republicans.

With most people aware of the latest vaccine, many, including large shares of previously vaccinated adults, have not yet received the updated shot and some dont plan to. About six in ten (58%) adults are previously vaccinated and have yet to get the updated vaccine. This group is roughly divided between people who say they will get the vaccine and those who say they are not planning to get the latest shot. The latest COVID-19 Vaccine Monitor survey explores why this group of previously vaccinated people have not gotten the latest dose.

Around half of adults (47%) have both previously received a COVID-19 vaccine and also say they will get or have already gotten the updated vaccine. On the other hand, one in five (20%) adults are previously unvaccinated and say they will not get the updated vaccine. That leaves three in ten (31%) who have previously been vaccinated but now say they will not get the updated shot.

More than four in ten Republicans (43%) and one in three independents (35%) say they are previously vaccinated but wont get the updated shot, compared to 19% of Democrats. A larger share of White adults (34%) also report being previously vaccinated but not planning on getting the latest shot compared to Black adults (20%). Around a quarter of Hispanic adults (26%) are previously vaccinated but now do not plan to get the latest vaccine.

In 2021, KFF surveys examining initial vaccine rollout found that concerns about vaccine safety were the driving reason why people didnt get vaccine. Even as those concerns dissipated among most of the public, a small share of the public remained steadfast and never received a COVID-19 vaccine. Yet, subsequent booster never reached the same uptake levels as seen in the initial vaccine rollout. And as the country enters its fourth year of COVID-19 concerns, it appears this trend continues.

When asked about a series of reasons that could explain why people are not getting the latest vaccine, not being worried about getting COVID-19 tops the list. About half (52%) of those who were previously vaccinated say lack of worry about COVID-19 is at least a minor reason why they havent gotten the vaccine, including a quarter who say it is a major reason. Getting vaccinated may also not be a priority for some with around four in ten (37%) saying being too busy is at least a minor reason why they have not gotten it yet, and another third saying they are waiting to get it a later date. Experiences from previous doses may also be keeping people from getting the new vaccine with about a quarter saying that bad side effects from a previous COVID-19 vaccine dose is a reason why they have not gotten the new vaccine.

Small shares say there are other barriers to getting the vaccine including 16% who say they cannot take the time off work and 13% who say they havent been able to get an appointment. One in ten (11%) say their doctor told them to wait or to not to get the updated vaccine.

Among Hispanic adults who were previously vaccinated but have not gotten the new shot, about half (55%) say they arent worried about getting COVID-19, they are too busy (51%), or they are waiting to get it at a later date (48%). In addition, a third (35%) of Hispanic adults as well as a quarter (22%) of Black adults cite not being able to take time off work, compared to just one in ten (9%) White adults.

Democrats top reasons for not getting the updated COVID-19 vaccine suggests there will likely still be additional uptake in this group, while Republicans top reasons may indicate more resistance to the latest vaccine. Among those who were previously vaccinated but havent gotten the new shot, half of Democrats (49%) say being too busy is a major or minor reason they havent gotten the updated vaccine yet, compared to 22% of Republicans and 35% of independents. On the other hand, two-thirds of Republicans (66%) and more than half of independents (57%) say not being worried about getting COVID is at least a minor reason why they have not gotten the updated vaccine, compared to a third of Democrats (35%).

With fall and winter holidays coming up, the possibility of a further wave of COVID-19 infections is looming with increased indoor gatherings and time with friends and family. Yet, most of the public is not worried about spreading or catching COVID-19 over the coming months. About three in ten adults are worried they will spread COVID-19 to people close to them (31%) or they will get seriously sick from COVID-19 (28%), and about a quarter (26%) are worried they will get COVID-19 over the holidays. A larger share of the public is worried about increased hospitalizations, with almost half (46%) saying they are very or somewhat worried that there will be an increase in hospitalizations in the U.S. this winter.

Older adults are not more worried than younger adults about the spread of COVID-19 this holiday season except for concerns about increases in cases and hospitalizations. Around half (53%) of adults ages 65 and older say they are worried that there will be an increase in COVID-19 cases and hospitalizations this winter, compared to smaller shares (44%) of those under the age of 65.

Around the same share say they are very or somewhat worried about an increase in COVID-19 cases and hospitalizations this winter as were in December of last year when there was a similar uptick in COVID-19 cases.

In addition to not being worried about COVID-19 during the upcoming holidays, the public is divided on precautions, with half of adults saying they arent planning to take any of the precautions asked about in the survey, while the other half report they plan to take at least one precaution this fall and winter. The most common precautions people said they planned to take were avoiding large gatherings (35%) or wearing a mask in crowded places (30%). Smaller shares say they are avoiding travel this fall and winter as a precaution against COVID-19 (25%), avoiding dining indoors at restaurants (19%), or taking a COVID-19 test before visiting with friends or family (18%).

The share who say they plan to take precautions to limit the spread of COVID is similar to the share of the public who said they were taking precautions because of the tripledemic back in January of this year. Back then, about half (46%) of adults said the news of COVID-19, RSV, and the flu spreading that winter had made them more likely to take a precaution, including three in ten (31%) who said they were more likely to wear a mask in public and a quarter (26%) who were more likely to avoid large gatherings.

While four in ten (39%) White adults say they will take at least one precaution, majorities of Black adults (72%) and Hispanic adults (68%) report they are planning to take any of the precautions mentioned.

Similarly, partisanship and previous vaccine uptake continue to be strong predictors of whether people plan to take precautions to limit the spread of the virus. Two thirds (66%) of Democrats and half (48%) of independents say they plan to take at least one precaution, compared to three in ten (29%) Republicans who say the same. Just over half (53%) of vaccinated adults say they are taking any of the precautions, compared to four in ten (39%) unvaccinated adults.

Similar shares of younger and older adults report that they will be taking at least one precaution during the fall and winter. However, four in ten (41%) adults ages 65 and older say they plan to avoid large gatherings, compared to a third (33%) of those under the age of 65. While younger adults are less likely to say they will avoid large gatherings, larger shares of younger adults say they will take a test for COVID-19 before spending time with friends of family, with 21% who say so (including 25% of those ages 18-29), compared to one in ten (10%) of those ages 65 and older.

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KFF COVID-19 Vaccine Monitor November 2023: With COVID ... - KFF

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What to Know About the New Dominant Covid Variant – The New York Times

Posted: August 12, 2023 at 7:24 am

Concern is rising about the Covid-19 variant EG.5. This week, it became the dominant variant in the United States, and the World Health Organization classified EG.5 as a variant of interest, meaning it has genetic changes that give it an advantage and its prevalence is growing. So how worried should people be about it?

While severe illness in older adults and people with underlying conditions is always a concern, as is long Covid in anyone who gets infected, experts say EG.5 does not pose a substantial threat or at least no more of one than any of the other major variants currently circulating.

Its a concern that its increasing, but it doesnt look like something thats vastly different from whats already been circulating in the U.S. for the past three to four months, said Andrew Pekosz, a professor of molecular microbiology and immunology at Johns Hopkins University Bloomberg School of Public Health. So I think thats what tempers my concern about this variant, at this point in time.

Even the W.H.O. stated in its announcement that, based on the available evidence, the public health risk posed by EG.5 is evaluated as low at the global level.

The variant was identified in China in February 2023 and was first detected in the United States in April. It is a descendant of the Omicron variant XBB.1.9.2 and has one notable mutation that helps it to evade antibodies developed by the immune system in response to earlier variants and vaccines. That advantage may be why EG.5 has become the dominant strain worldwide, and it could be one reason Covid cases have started to rise again.

That mutation may mean that more people are susceptible because the virus can escape a little bit more of that immunity, Dr. Pekosz said.

But EG.5, which has also been called Eris, does not appear to have any new capacities when it comes to its contagiousness, its symptoms or its likelihood of causing severe illness. Diagnostic tests and treatments such as Paxlovid continue to be effective against it, Dr. Pekosz said.

Dr. Eric Topol, executive vice president of Scripps Research in La Jolla, Calif., said he isnt overly worried about the variant; however, he would feel better if the new vaccine formulation, which is expected to be rolled out in the fall, was already available. The updated booster was developed based on another variant that is genetically similar to EG.5. It is expected to provide better protection against EG.5 than last years shot, which targeted the original coronavirus strain and a much earlier Omicron variant that is only distantly related.

My main concern is for the people at high risk, Dr. Topol said. The vaccines that theyve had are too far removed from where the virus is right now and where its going.

Experts are more apprehensive about other emerging variants that carry the same immune evading mutation as EG.5, plus another mutation that makes the virus more transmissible. Scientists have nicknamed the combination of these mutations FLip, because they both flip the positions of two amino acids, labeled F and L. While these FLip variants make up only a small proportion of Covid cases currently, they could trigger a greater increase in infections in the coming months.

Im generally very concerned about the overall rate of evolution for SARS-CoV-2, said Trevor Bedford, a professor in the vaccine and infectious disease division at Fred Hutchinson Cancer Center. No single variant has been that impactful, but the overall accumulation of these mutations is having significant impact.

Despite the growing number of mutations, it is highly unlikely these new variants will cause a surge akin to the one that occurred in the winter of 2022 with the first Omicron variant, Dr. Topol said. Its nothing like what weve been through with Omicron in terms of how much more transmissible these variants are, he said. But there will be more reinfections.

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What to Know About the New Dominant Covid Variant - The New York Times

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