PRINCETON, N.J.--(BUSINESS WIRE)--Bristol Myers Squibb (NYSE: BMY) today announced the presentation of scientific research across cancers and blood disorders at the 2022 American Society of Clinical Oncology (ASCO) Annual Meeting and the European Hematology Association (EHA) Congress that underscores the companys commitment to delivering transformational therapies for patients. Data from more than 140 company-sponsored studies, investigator-sponsored studies and collaborations evaluating compounds across 28 cancer types and blood disorders will be featured at the two meetings.
We have made significant progress for patients with cancer and blood disorders by delivering clinically meaningful and differentiated treatment choices across modalities such as CAR T, immunotherapy and erythroid maturation, said Samit Hirawat, M.D., executive vice president, chief medical officer, Global Drug Development, Bristol Myers Squibb. Driven by our deep understanding of human biology and leading scientific research, the results being presented at ASCO and EHA will provide greater insight into the potential for improving long-term outcomes, and rationale for moving innovative interventions into earlier lines of treatment. Beyond our data, we are focused on improving care for all patients through our Health Equity Commitments, aimed at increasing diversity in clinical trials, addressing health disparities, and investing in training for racially and ethnically diverse clinical investigators.
Key data being presented by Bristol Myers Squibb at ASCO and EHA 2022 include:
Solid Tumor
Cell Therapy
Hematology
Early Assets
Summary of Presentations
Select Bristol Myers Squibb studies at the 2022 ASCO Annual Meeting include:
Abstract Title
Author
Presentation Type/#
Session Title
Session Date/ Time
Acute Myeloid Leukemia
Health-related quality of life (HRQoL) with enasidenib versus conventional care regimens in older patients with late-stage mutant-IDH2 relapsed or refractory acute myeloid leukemia (R/R AML).
Courtney DiNardo
Poster
Abstract #7032
Hematologic MalignanciesLeukemia, Myelodysplastic Syndromes, and Allotransplant
Saturday, June 4, 2022: 9:00 AM - 12:00 PM EDT
Assessing eligibility for non-intensive chemotherapy (IC) randomized clinical trials (RCT) in patients (pts) with newly diagnosed (ND) AML from the Connect Myeloid Disease Registry.
Harry Erba
Poster
Abstract #7029
Hematologic MalignanciesLeukemia, Myelodysplastic Syndromes, and Allotransplant
Saturday, June 4, 2022: 9:00 AM - 12:00 PM EDT
Overall survival by IDH2 mutant allele (R140 or R172) in patients with late-stage mutant-IDH2 relapsed or refractory acute myeloid leukemia treated with enasidenib or conventional care regimens in the phase 3 IDHENTIFY trial.
Stephane De Botton
Oral
Abstract #7005
Hematologic MalignanciesLeukemia, Myelodysplastic Syndromes, and Allotransplant
Tuesday, June 7, 2022: 10:45 AM - 1:45 PM EDT
Gastrointestinal
Nivolumab (NIVO) plus chemotherapy (chemo) or ipilimumab (IPI) versus chemo as first-line (1L) treatment for advanced esophageal squamous cell carcinoma (ESCC): Expanded efficacy and safety analyses from CheckMate 648.
Ian Chau
Poster
Abstract
#4035
Gastrointestinal CancerGastroesophageal, Pancreatic, and Hepatobiliary
Saturday, June 4, 2022: 9:00 AM - 12:00 PM EDT
Nivolumab (NIVO) ipilimumab (IPI) in patients (pts) with microsatellite instability-high/mismatch repair-deficient (MSI-H/dMMR) metastatic colorectal cancer (mCRC): Five-year follow-up from CheckMate 142.
Michael Overman
Poster
Abstract
#3510
Gastrointestinal CancerColorectal and Anal
Saturday, June 4, 2022: 9:00 AM - 12:00 PM EDT
Genitourinary
Association between depth of response (DepOR) and clinical outcomes: Exploratory analysis in patients with previously untreated advanced renal cell carcinoma (aRCC) in CheckMate 9ER.
Cristina Suarez
Oral
Abstract
#4501
Genitourinary CancerKidney and Bladder
Friday, June 3, 2022: 3:45 PM - 6:45 PM EDT
The relationship between health-related quality of life (HRQoL) and clinical outcomes in patients with advanced renal cell carcinoma (aRCC) in CheckMate (CM) 214.
David Cella
Oral
Abstract
#4502
Genitourinary CancerKidney and Bladder
Friday, June 3, 2022: 3:45 PM - 6:45 PM EDT
Racial differences in treatment patterns and outcomes of first-line (1L) therapies for advanced renal cell carcinoma (aRCC) in the real-world (RW) setting.
Daniel Geynisman
Poster
Abstract
#4548
Genitourinary CancerKidney and Bladder
Saturday, June 4, 2022: 2:15 PM - 5:15 PM EDT
Prognostic value of the lung immune prognostic index in patients with untreated advanced renal cell carcinoma (aRCC) receiving nivolumab plus ipilimumab (N+I) or sunitinib (SUN) in the CheckMate 214 trial.
Lucia Carril-Ajuria
Poster
Abstract
#4538
Genitourinary CancerKidney and Bladder
Saturday, June 4, 2022: 2:15 PM - 5:15 PM EDT
Results for patients with muscle-invasive bladder cancer (MIBC) in the CheckMate 274 trial.
Alfred Witjes
Poster
Abstract
#4585
Genitourinary CancerKidney and Bladder
Saturday, June 4, 2022: 2:15 PM - 5:15 PM EDT
Melanoma
Nivolumab (NIVO) + relatlimab (RELA) versus NIVO in previously untreated metastatic or unresectable melanoma: OS and ORR by key subgroups from RELATIVITY-047.
Hussein A. Tawbi
Oral
Abstract
#9505
Melanoma/Skin Cancers
Sunday, June 5, 2022: 10:45 AM - 1:45 PM EDT
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