Monthly Archives: April 2022

Recognizing and treating disorders of gut-brain interaction – Harvard Health

Posted: April 25, 2022 at 5:28 pm

Dr. Freeman: "Mr. Vargas, great news on the biopsy results: all negative. It means the workup we have done, including imaging, blood work, and endoscopies, is all normal. Youre all set."

Mr. Vargas: "How can that be? I feel miserable!"

The clinical scenario above (names altered for privacy) is surprisingly common for gastroenterologists. These doctors of the esophagus, stomach, small intestines, colon, pancreas, and liver are well trained to identify and treat conditions of the gastrointestinal (GI) tract that occur from diseases caused by inflammation, infection, or cancer.

While some of these conditions can be devastating, they are usually easy to diagnose on standard testing. But there are other illnesses that can impact the GI tract that do not have a clear laboratory test or finding on endoscopy to identify them. One such class of these is called disorders of gut-brain interaction, or DGBIs. Some people (including doctors) may be familiar with the older term used to describe these conditions functional GI diseases but it is no longer used.

DGBIs can include irritable bowel syndrome, reflux hypersensitivity, or functional dyspepsia. They are called disorders of gut-brain interaction because it is believed the most critical abnormality is impaired communication between the gut and the brain via the nervous system in both directions (from gut to brain and brain to gut).

Some things are associated with the development of DGBIs, including having suffered from prior infections, particularly those that have symptoms like nausea or diarrhea. DGBIs are more prevalent in certain populations, including women. Depression and anxiety are independent illnesses that can be associated with DGBIs as well. Unfortunately, the mechanisms of why DGBIs happen are still not well defined, which can be frustrating for patients and their providers.

From the perspective of specialists like me, DGBI management is not given a lot of attention in clinical training. This can lead to unnecessary testing that has risks, including perforation from endoscopy or radiation from imaging. Even more confusing is that DGBIs can overlap with other GI diseases. As an example, functional dyspepsia (a type of chronic indigestion) can overlap with gastroparesis (slow stomach emptying). Irritable bowel syndrome can overlap with inflammatory bowel diseases (like ulcerative colitis and Crohns disease).

DGBIs can be treated with multiple primary approaches, and these can also be combined: lifestyle, including dietary approaches; medications; complementary/alternative medicine approaches; and behavioral therapy. Lifestyle and complementary and alternative medicine approaches can be attractive options for some patients.

While eliminating very fatty and processed foods may improve GI symptoms when you have a DGBI, it is hard to sustain such severe changes in diet to control symptoms, and when done too strictly can lead to other conditions, such as feeding difficulties from avoidant restrictive food intake disorder.

Some people might try a low-FODMAP diet (this should be avoided if youve had an eating disorder). You can try to avoid FODMAP (fermentable oligosaccharides, disaccharides, monosaccharides, and polyols)-containing foods for one month (ideally guided by a doctor and/or a dietitian), and completely return to a normal diet if there is no improvement. If there is improvement, then add back foods systematically to make sure your diet is varied and provides all necessary nutrients.

Sometimes people consider acupuncture, ginger, turmeric, or herbal supplements, which you should always discuss with your doctor to prevent side effects or serious health issues, including liver problems.

Medication-based approaches typically use medications that have been used to treat conditions like depression, neuropathy, and fibromyalgia. Sometimes doctors do not clearly explain the rationale for using such medications; however, they are meant to improve the gut-brain interaction by improving pain sensation pathways in the brain, and perhaps even stimulating improved nerve function.

Finally, GI-directed behavioral therapies use cognitive behavioral approaches to improve GI symptom-specific anxiety with the help of a psychologist or therapist.

If your doctor has identified that you have a DGBI, make sure to emphasize how much it is negatively impacting your quality of life. For a condition like irritable bowel syndrome, the change in bowel movements and the associated pain can really cause daily distress. Many DGBIs can affect your ability to do certain types of work that may not allow you easy access to a bathroom. DGBIs also affect sexual health.

Make sure your provider understands that managing your DGBI is important, and you want to work together to find the right treatment approaches (or a combination of approaches), as discussed above.

Beyond this, it is important to recognize that DGBIs are established diagnoses, and are just as valid as any other gastrointestinal disease. When you have symptoms of a DGBI, it is not because of an issue of willpower or weakness, or " just in your head." These are disorders for which good treatments exist, and they can improve your symptoms and quality of life.

As a service to our readers, Harvard Health Publishing provides access to our library of archived content. Please note the date of last review or update on all articles. No content on this site, regardless of date, should ever be used as a substitute for direct medical advice from your doctor or other qualified clinician.

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Recognizing and treating disorders of gut-brain interaction - Harvard Health

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Ear Seeds: What Is Ear Seeding and How Does It Work? Experts Explain – Good Housekeeping

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They look great in a pair of earrings, but chances are, you don't pay too much attention to your ears on a day-to-day basis. Yet social media influencers keeping up on the latest wellness trends have been seemingly obsessed with their ridged cartilage and lobes thanks to ear seeding, a modern take on acupressure that targets well-established acupuncture points within our ears.

In traditional Chinese medicine, the ear is considered a microsystem: A representation of the whole body. The ear looks like an upside-down baby with the lobe being the head, the interior ridge being the spine, and the internal organs along with the recessed areas, explains Tom Ingegno, a doctor of acupuncture and Chinese medicine based in Baltimore, Maryland.

Thats why, he explains, when pressure is applied to different spots of the ear in the ear seeding process, otherwise known as auriculotherapy, it can stimulate that point of the body. And when it does, it can help you in all sorts of ways by easing pain, lessening stress, easing allergies and more.

Ear seeds are, essentially, what they sound like: little seeds.

In traditional Chinese medicine, they are seeds of the Vaccaria plant, a type of seed that is roughly the size of poppy seeds. This [vaccaria plant] herb is used for its blood moving properties and also reduces swelling, relieves pain and promotes healing, says Sandra Subotich, a doctor of acupuncture and director of eastern medicine at Chicago-based Bian.

Today, ear seeds arent just seeds anymore. Some acupuncturists and stores sell some made of steel, silver, gold, crystal or magnets. Regardless of what theyre made of, the seeds are applied to different acupuncture spots of your ear using an adhesive or waterproof tape.

Once applied, you can wear the seeds all day or up to three to five days tops, if the adhesive holds.

Ear seeds are used to stimulate acupuncture points in the ear, by providing a constant stimulation, Subotich explains. Since the ear is a Microsystem of the entire body, ear seeds can be used to address a wide variety of issues.

These issues, according to Subotich, include sleep problems, stress and anxiety, depression, headaches, addiction, weight management and holistic pain management. Research on substantiated benefits associated with ear seeding is limited, but many practitioners convey these potential benefits to those interested in exploring naturopathic treatment options.

Ear seeding has enjoyed a boom in popularity during the pandemic. During these stressful times, ear seeding has included treating healthcare workers who are overworked and exhausted, explains Barbara Gosse, an acupuncturist and educator with Northwestern Health Sciences University, because they may help ease insomnia side effects, and help individuals deal with stress and anxiety.

Pressing on the seeds helps to more intensely stimulate the point and thereby stimulate the underlying nerves, Subotich says. This sends a stronger message through the neural pathways and helps to modulate the desired effect.

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In many ways, ear seeding is similar to acupuncture but it doesnt require any needles, which is an advantage to anyone thats got a bit of trypanophobia. Ear seeds are also easier to administer, which means that once you know where to put them, you can apply them yourself.

Ear seeds also only apply pressure to your ears skin, which makes it minimally invasive and now that the seeds are made of metals or even crystal, they can also be a bit of a fashion accessory because they look nice while you wear them. Ear seeds are also relatively low cost.

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According to those who practice traditional Chinese medicine, there are centuries of anecdotal evidence that it is effective for treating or at least easing the symptoms of many physical and psychological ailments. Thats why in 1957, Paul Nogier, a French physician, adopted the practice and published the ear map to help those in the west adopt the practice.

Unfortunately, though, there arent many large medical studies that have been published to back up the discussion of these benefits with direct correlation to ear seeds. Many smaller-scale studies, however, conducted independently have suggested that ear seeding may ease the pain on an individual basis.

A small 2013 study, for example, found that ear seeding could help reduce low back pain and improve mobility, while a 2015 study found the practice might increase pain tolerance. An older 2010 study shared in the Journal of Alternative Medicine also found ear seeding might relieve mild to moderate pain and a 2020 review of 14 other studies from Brazil found ear seeds could effectively reduce musco-skeletal pain. A 2021 study in the Journal of Personalized Medicine, meanwhile, found it could ease menstrual pain, causing people to need fewer pain medications.

Other studies have supported some of the other holistic health claims that ear seeding aficionados have floated in the past:

Still, says Ingegno, ear seeding works best on people who have moderate symptoms who are looking for simple relief and not expecting miracles. In addition, many people also find that it benefits them most when it is practiced alongside regular traditional acupuncture sessions.

The short answer? Yes! Ear seeds are generally considered safe to use as they are topically applied with little to no invasive materials used. There may be some application risks, however, that you should be aware of.

Some people are sensitive to the adhesive used to apply the seed (particularly if they have a latex allergy) or the metal of the seed itself, Gosse explains. This can cause some itching, discomfort or redness all signs that you should remove the ear seed right away.

Youll also want to avoid ear seeds if you have cracks, scratches or other injuries to your skin as the seeds could aggravate those injuries further.

In addition, Ingegno says, you dont want to leave them in place too long as you may develop a divot in the skin where the ear seed was placed.

Ear seeds generally stay in place pretty well but there is a small possibility they can fall off and fall into your ear canal, which could cause injury to your ear or lead to an infection. In 2015, the scientific community shared a record of what happened to a woman after the seed fell through a hole in her eardrum and had to be surgically removed.

You can buy ear seeds from an acupuncturist near you, which is recommended for ear seeding newcomers, as they often provide instruction or any of the products available online.

Consumer kits like the ones available from earseeds.com come with instructions, a chart of the relevant points and tweezers, Ingegno says.

That said, all the acupuncturists we spoke with recommended talking with a professional before trying ear seeds for the first time by yourself.

[If you] have your first treatment from a professional acupuncturist, they can help you decide which points are best for you, says Laura Erlich, acupuncturist and womens holistic health specialist with Mother Nurture Wellness in Los Angeles. They can also mark points in your ear with a skin-safe marker to make it easier for you to do at home.

Just make sure that while youre applying them, you use a mirror and tweezers to apply the seed to your ear, while consulting a diagram of the acupuncture points in your ear. Be aware that everyones ears have different shapes and that you might need to adjust placement based on the shape of your ear, Ingegno explains. Dont expect your ear to look exactly like the picture in the product's chart [and] dont stress about getting them perfect.

Given the variation in everyones ears, finding the perfect location may seem impossible so aim for close enough, he adds.

When its time to take them off, use a tweezer and tilt your head towards the ground so the seed doesnt accidentally fall into your ear canal.

You might also want to give your ears short breaks between ear therapy treatments so that the skin doesnt get aggravated over time. Some experts believe they stop being as effective when worn consistently. Ideally you want to change your seeds out every 3 days, as the body will get used to the pressure, says Subotich. I generally will leave my seeds in for no more than 5-7 days and then give my ears a break for a day or two.

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Ear Seeds: What Is Ear Seeding and How Does It Work? Experts Explain - Good Housekeeping

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Evusheld provides additional protection for immune-compromised patients against COVID-19 – University of Alabama at Birmingham

Posted: at 5:28 pm

Many people who are immunocompromised will not fully develop the appropriate antibodies after COVID-19 vaccination, but there is hope in the form of an alternative treatment.

Vineeta Kumar, M.D., Photography: Andrea MabryEven with multiple COVID-19 vaccines and boosters, there are still groups of people who do not receive the full benefit of vaccines due to immunosuppressed conditions that prevent the body from making sufficient antibodies. But one alternative treatment option is providing hope.

Known as Evusheld, the medication contains protective antibodies againstSARS-CoV-2.

The antibodies are given as two injections at the same time to a patient, and once injected they are in the system ready to work if the patient is exposed to another person with acute COVID-19 infection in the future.

Vineeta Kumar, M.D., professor of nephrology in the University of Alabama at Birminghams Marnix E. Heersink School of Medicine, says this is an effective option for immunocompromised populations, such as transplant patients.

We know that transplant recipients develop less of an antibody response to the vaccine due to their immunosuppressive medications, Kumar said.In other words, the medication or immunosuppressed condition may prevent their body from makingsufficient antibodies, and in some patientsanyantibody.This could result in a decrease in the vaccines ability to provide protection against COVID-19 infection.

Kumar adds that this treatment is meant to be given before a person has been exposed to another with COVID-19 infection.

Evusheld should notbe used as a substitute for vaccination or for primary prevention strategies, including masking, social distancing and avoidance of large indoor social gatherings, Kumar said. Vaccination of close contacts, including household members, continues to be an important measure to protect transplant recipients from COVID-19 infection.

For transplant patients, Kumar says it is crucial they receive the infusion as soon as they are cleared after the transplant.

Due to limited supply ofEvusheld nationwide, patients early after transplant or early after receiving medications that suppresses their immune system are prioritized to getEvusheldfirst, she said.

Anoma Nellore, M.D., Photography: Steve Wood She says it is possible that Evusheld may reduce the bodys immune response to a COVID-19 vaccine. If someone has received the COVID-19 vaccine, they should wait at least two weeks after vaccination to receive Evusheld; but booster doses of vaccine can be given any time after Evusheld has been administered.

We will continue to monitor response of the new virus variants to this infusion, Kumar said.

UAB and doctors across the state are still working to make sure as many people have it as possible.

And these include referrals through our state Department of Public Health and referrals from other medical centers, said Anoma Nellore, M.D., associate professor in the Division of Infectious Diseases. We want to make sure all patients are protected.

At UAB, Kumar is the Robert and Cutessa Bourge Endowed Professor in Transplant Nephrology.

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Evusheld provides additional protection for immune-compromised patients against COVID-19 - University of Alabama at Birmingham

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Covid Live Updates: Testing, Lockdowns, and More News – The New York Times

Posted: at 5:27 pm

In the middle of last year, the World Health Organization began promoting an ambitious goal, one it said was essential for ending the pandemic: fully vaccinate 70 percent of the population in every country against Covid-19 by June 2022.

Now, it is clear that the world will fall far short of that target by the deadline. And there is a growing sense of resignation among public health experts that high Covid vaccination coverage may never be achieved in most lower-income countries, as badly needed funding from the United States dries up and both governments and donors turn to other priorities.

The reality is that there is a loss of momentum, said Dr. Isaac Adewole, a former health minister of Nigeria who now serves as a consultant for the Africa Centers for Disease Control and Prevention.

Only a few of the worlds 82 poorest countries including Bangladesh, Bhutan, Cambodia and Nepal have reached the 70 percent vaccination threshold. Many are under 20 percent, according to data compiled from government sources by the Our World in Data project at the University of Oxford.

By comparison, about two-thirds of the worlds richest countries have reached 70 percent. (The United States is at 66 percent.)

The consequences of giving up on achieving high vaccination coverage worldwide could prove severe. Public health experts say that abandoning the global effort could lead to the emergence of dangerous new variants that would threaten the worlds precarious efforts to live with the virus.

This pandemic is not over yet far from it and its imperative that countries use the doses available to them to protect as much of their population as possible, said Dr. Seth Berkley, chief executive of Gavi, the nonprofit that runs the global vaccine clearinghouse Covax.

Countries in different parts of the world, including some in Eastern Europe and the Middle East, have seen their vaccination rates stagnate in recent months at a third or less of their populations. But Africas vaccination rate remain the most dismal.

Fewer than 17 percent of Africans have received a primary Covid immunization. Nearly half of the vaccine doses delivered to the continent thus far have gone unused. Last month, the number of doses injected on the continent fell by 35 percent compared to February. W.H.O. officials attributed the drop to mass vaccination pushes being replaced by smaller-scale campaigns in several countries.

Some global health experts say the world missed a prime opportunity last year to provide vaccines to lower-income countries, when the public was more fearful of Covid and motivated to get vaccinated.

There was a time people were very desperate to get vaccinated, but the vaccines were not there. And then they realized that without the vaccination, they didnt die, said Dr. Adewole, who wants to see countries continue to pursue the 70 percent target.

What momentum remains in the global vaccination campaign has been hindered by a shortfall in funding for the equipment, transportation and personnel needed to get shots into arms.

In the United States, a key funder of the vaccination effort, lawmakers stripped $5 billion meant for global pandemic aid from the coronavirus response package that is expected to come up for a vote in the next few weeks. Biden administration officials have said that without the funds, they will be unable to provide support for vaccine delivery to more than 20 under-vaccinated countries.

Some public health experts point to reasons for optimism that the global vaccination campaign still has steam. Despite the drop off from the February peak, the number of Covid vaccinations being administered each day in Africa is still near a pandemic high. And Gavi earlier this month drew a significant new round of funding pledges, securing $4.8 billion in commitments, although it fell short of its $5.2 billion goal.

There is also hope that a global Covid summit the White House plans to co-host next month could be an opportunity to generate momentum and funding.

But the drop in public demand has led some health officials and experts to quietly, and in some cases outright, question whether the 70 percent vaccination target is feasible or even sensible.

Reported fatalities from Covid-19 remain comparatively low in sub-Saharan Africa, although there is debate about how much of this reflects poor data tracking. The perception, however, in many countries in the region is that the disease does not pose a serious threat, certainly not as much as other pervasive health problems that demand attention with scarce health care resources.

Many lower-income governments are turning their focus to their economies and other health issues like H.I.V., said Fifa Rahman, a civil society representative to a W.H.O.-launched group coordinating the global Covid response. Theres a sense of a lot of competing priorities, but thats a symptom of the momentum being gone. Because when the momentum was there, everyone was like, Where are our vaccines?

In rural areas of the Democratic Republic of Congo, for example, where the reported Covid death rate is very low, there is a surge in measles cases threatening 20 million children. Yet the government says it cannot spare the resources to provide supplementary measles vaccinations this year, said Christopher Mambula, medical manager for Doctors Without Border in East Africa. In this kind of context, it makes little sense to continue to divert resources to widespread vaccination against Covid, he said.

As African governments have received more vaccines donated from wealthy countries and struggled to distribute even those supplies, their interest in ordering more doses has dropped.

The African Union still aims to vaccinate 70 percent of its population by the end of 2022. But with countries slow to use up donated vaccines, the bloc has not exercised its options to order more doses of the shots from Johnson & Johnson and Moderna.

The South African drugmaker Aspen Pharmacare earlier this year finalized a deal to bottle and market the Johnson & Johnson vaccine across Africa, a contract that was billed as an early step toward Africas development of a robust vaccine production industry. Aspen geared up for production, but no buyers, including the African Union and Covax, have placed orders yet, said Stephen Saad, Aspens chief executive.

The Serum Institute of India, the worlds largest vaccine maker, stopped its production of Covid shots in December last year, when its stockpile grew to 200 million doses; Bharat Biotech, another Indian firm that was a major producer, also stopped making vaccines in the face of low demand. The companies say they have no further orders since their contracts with the Indian government ended in March.

After the W.H.O. began promoting the 70 percent vaccination goal, many lower-income governments adopted the target for their own populations. The Biden administration also endorsed it last September, setting a deadline of September 2022.

At the time, two doses of the vaccines from Pfizer and Moderna were understood to offer very strong protection against even mild disease, and there was still hope that achieving high levels of vaccination coverage would tame the virus. But the emergence of new variants and the spread of the virus in Africa changed the calculus.

The vaccine regimens that had been planned for the developing world offered little protection against infection with the Omicron variant. And as sub-Saharan African countries were shut out of vaccine distribution for much of last year, more and more Africans gained protection against the virus from natural infection, which studies have shown works as well as two mRNA doses in preventing infection. New data from the W.H.O. shows that at least two-thirds of Africans had been infected with the virus before the Omicron wave.

Given these factors, some public health experts in Africa say the broad 70 percent goal no longer makes sense. Theres very little value to it. In fact, we will gain much more by getting to more than 90 percent of people above the age of 50, said Shabir Madhi, a professor of vaccinology and the dean of the faculty of health sciences at the University of the Witwatersrand in Johannesburg. About two-thirds of South Africans above age 50 are currently fully vaccinated.

Dr. Madhi said that South Africa could close down mass vaccination sites and instead redouble its efforts to seek out the most vulnerable at church services and at government offices that pay out monthly pension benefits.

Katherine OBrien, who directs the W.H.O.s work on vaccines and immunizations, said the agency encourages countries to focus on its most vulnerable citizens rather than vaccinating a random set of 70 percent of their populations. The aspiration she said, has always been 100 percent of health workers, 100 percent of older adults, 100 percent of pregnant women, 100 percent of the people who fall into those highest risk groups.

Countries can of course make decisions about what health goal they wish to prioritize, Dr. OBrien said, but finite resources should not be the obstacle to vaccinating against the coronavirus. The world has enough resources to do this, if countries want to do it, she said. And that should be really the North Star.

Some public health experts said that while the 70 percent vaccination threshold is clearly not achievable by its original deadline, it would be unwise and unethical to give up on that target over a longer time horizon. They expressed frustration about the growing gulf between wealthy countries vaccinating young children and offering healthy adults fourth vaccine doses, and the regions where the majority of people still do not have one dose.

Why are we making it one target for high-income countries and one target for low income? said Dr. Ayoade Alakija, a co-chair of the African Unions vaccine delivery program.

She said that even though many people in sub-Saharan Africa have been infected, there is still need for the additional protection that would come from a high level of vaccination coverage.

Modest vaccination coverage, she said, is not considered a good enough level of protection in England, its not a good enough level of protection in America. How is it OK not to be aiming for the very maximum, maximum we can? Aim for the sky and get to the top of the tree.

April 23, 2022

An earlier version of this article misspelled the surname of the chief executive of Gavi. He is Dr. Seth Berkley, not Berkeley.

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Covid Live Updates: Testing, Lockdowns, and More News - The New York Times

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NY COVID cases surge 37%. CDC urges wearing masks in these 23 counties – The Journal News

Posted: at 5:27 pm

Mask mandates returning to some college campuses

The final weeks of the college school year have been disrupted yet again by COVID-19 as universities bring back mask mandates. (April 22)

AP

New York's COVID-19 case tally surged 37% last week while hospitalizations spiked 24%, promptinghealth officials to expand recommendations to wear masks indoors in public spaces across 23 counties.

New York reported 49,500 cases in the week ending Sunday, up from36,180 new cases the prior week. COVID-19 patients admitted to hospitals statewide last week totaled 3,219, up from 2,603.

New York ranked second among the states where coronavirus was spreading the fastest on a per-person basis, a USA TODAY Network analysis of Johns Hopkins University data shows.

The uptick in COVID-19 infections and hospitalizations stemmed in part from the spread of highly contagious omicron subvariants, health officials noted, with recent holiday gatherings held indoorsoffering potentialvenues for fuelingoutbreaks.

Nationally, coronavirus casesincreased about 57% from the week before, with 351,599 cases reported.Across the country, 42 states had more cases in the latest week than they did in the week before.

Indoor mask wearingrecommendations for 23 "high-risk" countiesnow covered large sections of upstate New York, including much of the Finger Lakes and Southern Tier, according to the Centers for Disease Control guidelines based on COVID-19 infection rates and the strainon local hospitals. That's up from 10 counties on April 18.

Here are the "high-risk" NY counties:

Another 16counties across the state, including Westchester, currently fall under the "medium-risk" category, meaning recent case and hospitalization trends could soon warrant masking in public spaces.

While still well below the initial omicron strain's peak in earlyJanuary, when New York reported90,000 new cases in one day, the rise in infections and hospitalizations over the past month illustratedthe virus' ability to keep mutatingand spreading.

Some prior waves of infections during the pandemic, however, have receded as weather conditions improved and people spent more time outdoors where the virus struggles to spread.

Yet therise of the omicron subvariants has fueled the current uptick in cases, as authorities tried to balance the push to reduce pandemic-related disruptions to daily life against the need to renew calls forpeople to take steps to limit the virus' spread, such as mask wearing.

Further, New York'smask mandate for all public transit settings statewide will remain in place for the "short term" despite a Florida judge voiding a federal mask mandate for public transportation, Gov. Kathy Hochul said last week.

Meanwhile, COVID-19 deaths have begun to increase in New York after lagging behind infections and hospitalizations. A total of117 people were reported deadof COVID-19 in the week ending Sunday, up from59 deaths the prior week.

MASKS:Hochul: NY's mask mandate for public transit remains in place despite federal court ruling

Within New York, the worst weekly outbreaks on a per-person basis were in:

The Centers for Disease Control says high levels of community transmission begin at 100 cases per 100,000 per week. Weekly case counts rose in 61 of 62 counties across New York from the previous week.

>> See how your community has fared with recent coronavirus cases

New York ranked 7th among states in share of people receiving at least one shot, with 90.1% of its residents at least partially vaccinated. The national rate is 77.5%, a USA TODAY analysis of CDC data shows. The Pfizer and Moderna vaccines, which are the most used in the United States, require two doses administered a few weeks apart.

In the week ending Sunday, New York reported administering another 193,193 vaccine doses, including 25,351 first doses. In the previous week, the state administered 245,669 vaccine doses.

A total of 5,123,612 people in New York have tested positive for the coronavirus since the pandemic began, and 68,231 people have died from the disease, Johns Hopkins University data shows. In the United States 80,984,914 people have tested positive and 991,254 people have died.

>> Track coronavirus cases across the United States

USA TODAY analyzed federal hospital data as of Sunday, April 24.

Likely COVID patients admitted in the state:

Likely COVID patients admitted in the nation:

Hospitals in 37 states reported more COVID-19 patients than a week earlier, while hospitals in 25 states had more COVID-19 patients in intensive-care beds. Hospitals in 42 states admitted more COVID-19 patients in the latest week than a week prior, the USA TODAY analysis of U.S. Health and Human Services data shows.

The USA TODAY Network is publishing localized versions of this story on its news sites across the country, generated with data from Johns Hopkins University and the Centers for Disease Control. If you have questions about the data or the story, contact Mike Stucka at mstucka@gannett.com.

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NY COVID cases surge 37%. CDC urges wearing masks in these 23 counties - The Journal News

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74 new COVID-19 cases reported last week in Beaufort County, 4 in Jasper County – Bluffton Today

Posted: at 5:27 pm

Mike Stucka USA TODAY NETWORK| Bluffton Today

New coronavirus cases leaped in South Carolina in the week ending Sunday, rising 67.9% as 1,496 cases were reported. The previous week had 891 new cases of the virus that causes COVID-19.

South Carolina ranked 40th among the states where the coronavirus was spreading the fastest on a per-person basis, a USA TODAY Network analysis of Johns Hopkins University data shows. In the latest week coronavirus cases in the United States increased 57.1% from the week before, with 351,599 cases reported.

With 1.55% of the country's population, South Carolina had 0.43% of the country's cases in the last week. Across the country, 42 states had more cases in the latest week than they did in the week before.

Beaufort County reported 74 cases and zero deaths in the latest week. A week earlier, it had reported 48 cases and zero deaths. Throughout the pandemic it has reported 43,130 cases and 376 deaths.

Jasper County reported four cases and zero deaths in the latest week. A week earlier, it had reported one case and zero deaths. Throughout the pandemic it has reported 5,893 cases and 93 deaths.

Within South Carolina, the worst weekly outbreaks on a per-person basis were in McCormick County with 85 cases per 100,000 per week; Kershaw County with 69; and Allendale County with 46. The Centers for Disease Control says high levels of community transmission begin at 100 cases per 100,000 per week.

Adding the most new cases overall were Charleston County, with 180 cases; Greenville County, with 158 cases; and Richland County, with 154. Weekly case counts rose in 37 counties from the previous week. The worst increases from the prior week's pace were in Richland, Greenville and York counties.

>> See how your community has fared with recent coronavirus cases

South Carolina ranked 34th among states in share of people receiving at least one shot, with 67.3% of its residents at least partially vaccinated. The national rate is 77.5%, a USA TODAY analysis of CDC data shows. The Pfizer and Moderna vaccines, which are the most used in the United States, require two doses administered a few weeks apart.

In the week ending Sunday, South Carolina reported administering another 1,078 vaccine doses, including 1,346 first doses. In the previous week, the state administered 1,096 vaccine doses, including 1,627 first doses. In all, South Carolina reported it has administered 7,389,108 total doses.

Across South Carolina, cases fell in five counties, with the best declines in Abbeville County, with 2 cases from 5 a week earlier; in Greenwood County, with 11 cases from 13; and in Bamberg County, with 0 cases from 1.

In South Carolina, 36 people were reported dead of COVID-19 in the week ending Sunday. In the week before that, 48 people were reported dead.

A total of 1,472,093 people in South Carolina have tested positive for the coronavirus since the pandemic began, and 17,734 people have died from the disease, Johns Hopkins University data shows. In the United States 80,984,914 people have tested positive and 991,254 people have died.

>> Track coronavirus cases across the United States

USA TODAY analyzed federal hospital data as of Sunday, April 24.

Likely COVID patients admitted in the state:

Likely COVID patients admitted in the nation:

Hospitals in 37 states reported more COVID-19 patients than a week earlier, while hospitals in 25 states had more COVID-19 patients in intensive-care beds. Hospitals in 42 states admitted more COVID-19 patients in the latest week than a week prior, the USA TODAY analysis of U.S. Health and Human Services data shows.

The USA TODAY Network is publishing localized versions of this story on its news sites across the country, generated with data from Johns Hopkins University and the Centers for Disease Control. If you have questions about the data or the story, contact Mike Stucka at mstucka@gannett.com.

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74 new COVID-19 cases reported last week in Beaufort County, 4 in Jasper County - Bluffton Today

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Coronavirus News Live Updates: India reports 2,541 fresh Covid-19 cases, slightly lower than yesterday; active cases over 16,500 – The Indian Express

Posted: at 5:27 pm

As the fear of getting fined for not wearing masks set in after the DDMA order, people in the national capital have again started masking up in public places, especially at busy markets, railway stations, Metro, buses and ISBTs. The inspection by the Delhi Police and authorities at these places has also intensified again.

Delhi on Sunday reported 1,083 fresh COVID-19 infections with a positivity rate of 4.48 per cent, while one person died due to the disease, according to the health department. The infection tally in the national capital now stands at 18,74,876 and the death toll at 26,168. The capital had reported 1,094 COVID-19 infections on Saturday, highest since February 10, with a positivity rate of 4.82 percent and two deaths.

Meanwhile, Mumbai on Sunday reported 73 new coronavirus positive cases, which took its overall infection count to 10,59,286, according to PTI. The death toll in the metropolis remained unchanged at 19,562 as nobody succumbed to the infection during the day. On Saturday, the city had reported 72 cases.

A common anti-inflammatory drug has been found to be an effective antiviral agent in the treatment of mild and moderate Covid-19 patients. The drug, indomethacin, is widely used to treat various types of inflammation-related conditions. The study on Covid patients, by IIT Madras, has been published in Nature Scientific Reports.

THE DRUG: Indomethacin is a non-steroidal anti-inflammatory drug available as capsules and a liquid suspension, to be taken orally. According to the US National Library of Medicine, indomethacin works by stopping the bodys production of a substance that causes pain, fever, and inflammation. It is used to relieve moderate to severe pain, tenderness, swelling, and stiffness caused by various kinds of arthritis, and pain in the shoulder caused by inflammation.

The findings: A randomised clinical trial was conducted by IIT Madras researchers at Panimalar Medical College and Research Institute, Chennai. Out of 210 patients admitted, 107 were randomly allocated to a control group and treated with paracetamol and standard care, while 103 patients were administered indomethacin along with standard care of treatment, a media release from IIT Madras said.

Also read | New Research: Common drug found effective against mild and moderate Covid

A UK patient with a severely weakened immune system had Covid-19 for almost a year and a half, scientists reported, underscoring the importance of protecting vulnerable people from the coronavirus. Theres no way to know for sure whether it was the longest-lasting Covid-19 infection because not everyone gets tested, especially on a regular basis like this case.

But at 505 days, it certainly seems to be the longest reported infection, said Dr. Luke Blagdon Snell, an infectious disease expert at the Guys and St. Thomas NHS Foundation Trust.

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Elderly continue to be hardest hit by coronavirus – The Sun Chronicle

Posted: at 5:27 pm

According to the state Department of Public Health, the average age of those dying from coronavirus is now 79.

And the statistics DPH presents bear it out.

Currently, 91% of all deaths are among those 60 and up and 54% of all deaths are among those 80 and up.

The latest two-week period between April 3 and April 16 showed a surge of 8,697 cases to 13,113, which was an increase of 51%.

During that time there were 6,086 cases among those from the age of 0 to 19 and no deaths.

There were 16,166 cases among those from the age of 20 to 59 and just four deaths.

Those from the age of 60 to 80 and above had 4,496 cases and 57 deaths.

Those 80 and over suffered the most deaths, with 35, or 57%, of the 61 deaths during that period.

Since the beginning of the pandemic in March of 2020, those 80 and over have suffered 54% of all deaths, which is 10,943 out of 20,208 total deaths.

And during that time, that age group has had the fewest number of cases at 54,853, which is 3% of all 1,733,156 cases as of April 16.

Meanwhile, those from the age of 70 to 79 have suffered 4,678 deaths, which is 23% of the 20,208 total deaths as of April 16.

That groups percentage of deaths is less than half the 80 and over group, but their percentage of cases is slightly more at 4%.

Those from the age of 20 through the age of 59 account for 60% of all cases and 9% of all deaths.

Those numbers are 1,048,158 and 1,851, respectively.

Those 1,851 deaths is a death percentage of just 0.17%, or just under two-tenths of one percent, for the number of cases which afflicted the group.

And the youngest group of those afflicted with coronavirus, those from the age of 0 through 19, account for 24% of all cases and 0.11%, or one-tenth of 1%, of all deaths; those numbers are 416,395 and 23, respectively.

Meanwhile, as the number of cases rose, the number of those being cared for in intensive care units, or ICUs, fell.

On Friday, when the number of cases for the week ending April 22 hit 13,198, the number of those in ICUs fell from 37 to 25 since the week ending April 15.

And the number of those intubated with breathing apparatus declined from 15 to 12.

The numbers of those in ICUs and on breathing apparatus indicates this latest surge is less deadly.

On Friday, there were 389 people hospitalized statewide with 12 on breathing apparatus and 25 in an ICU.

The last time there were that many people hospitalized (391) on Feb. 28, about two months ago, there were 39 patients on breathing apparatus and 71 patients in ICUs.

George W. Rhodes can be reached at 508-236-0432.

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Elderly continue to be hardest hit by coronavirus - The Sun Chronicle

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Where Americans Stand on Coronavirus and Mask Mandates on Planes: Long Island University Hornstein Center National Poll – PR Newswire

Posted: at 5:27 pm

BROOKVILLE, N.Y., April 25, 2022 /PRNewswire/ -- Results of a newly released Long Island University Steven S. Hornstein Center for Policy, Polling and Analysis national poll revealed what Americans think about wearing masks on planes and public transportation in light of a federal court order, that stated as of April 18, 2022, the CDC's Order requiring masks on public transportation conveyances and at transportation hubs was no longer in effect.

MIXED SUPPORT (42%) ON THE REMOVAL OF MASK MANDATES ONBOARD AIRLINE FLIGHTS

Americans were asked if they supported the removal of mask mandates onboard airline flights to reduce the likelihood of contracting the coronavirus; 42% of respondents said yes. Respondents with the highest support of the mask mandate removal were Republicans (73%), followed by Independents (41%) and Democrats (21%). Support of the mask mandate removal was higher in the Midwest (48%) and South (47%) than other regions in the Northeast (33%) and Pacific (35%). Respondents age 60 and older supported the mask mandate removal at a lower rate (34%) than other age brackets. Males supported the mask mandate removal at a higher rate (46%) than females (39%).

6 OUT OF 10 AMERICANS WOULD STILL WEAR A MASK WHILE TRAVELING

National poll results found that 64% of respondents said they would still wear a mask today if traveling by plane; 63% of respondents said they would still wear a mask today if traveling on public transportation. Political beliefs played a factor in respondents' choices: 87% of Democrats said they would still wear masks on planes; 84% of Democrats said they would still wear masks on public transportation; 61% of Independents said they would still wear masks on planes; 59% of Independents said they would still wear masks on public transportation; 38% of Republicans said they would still wear masks on planes; 41% of Republicans said they would still wear masks on public transportation.

71% OF AMERICANS BELIEVE WEARING MASKS REDUCES THE LIKELIHOOD OF CONTRACTING THE CORONAVIRUS

Respondents were asked if they believe wearing face masks reduces the likelihood of contracting the coronavirus: 71% of Americans said yes; 92% of Democrats said yes; 68% of Independents/Other said yes; 46% of Republicans said yes.

HALF OF AMERICANS (53%) SAID THE WORST OF THE CORONAVIRUS PANDEMIC IS OVER

Respondents were asked if they believe the worst of the pandemic is over. Overall, 53% of respondents said yes, the highest since June 2021 through national polls conducted by the Long Island University Steven S. Hornstein Center for Policy, Polling and Analysis. Respondents with the highest confidence level that the worst of the coronavirus pandemic is over are Republicans (70%), followed by Independents (51%) and Democrats (43%).Respondents age 18-29 believe the worst is over at the highest belief rate (58%) compared to respondents age 60 and older (47%) at the lowest belief rate. Males believe the worst is over at a higher rate (57%) than females (49%).

53% OF AMERICANS SAID THEY CURRENTLY WEAR A MASK TO AVOID CONTRACTING THE CORONAVIRUS

Respondents were asked if they were currently wearing a mask in general to reduce the likelihood of contracting the coronavirus: 53% of Americans said yes; 73% of Democrats said yes; 48% of Independents/Other said yes; 34% of Republicans said yes.

62% OF AMERICANS REMAINED CONCERNED OVER RISK OF FAMILY CONTRACTING THE CORONAVIRUS (DOWN SLIGHTLY FROM 69% IN NOVEMBER 2021)

Americans were asked how concerned they are about someone in their family becoming seriously ill from the coronavirus: 62% of respondents said they are somewhat or seriously concerned as compared to 69% in an earlier November 2021 Hornstein Center national poll.78% of Democrats, 59% of Independents/Other, and 43% of Republicans said they are somewhat or seriously concerned.

75% OF AMERICANS ARE FULLY VACCINATEDAGE 12 AND OVER (UP FROM 69% IN NOVEMBER 2021)

76% OF AMERICANS ARE FULLY VACCINATEDAGE 18 AND OVER (UP FROM 71% IN NOVEMBER 2021)

90% OF AMERICANS ARE FULLY VACCINATEDAGE 65 AND OVER (UP FROM 86% IN NOVEMBER 2021)

According toCDC data, 75% of Americans age 12 and over are fully vaccinated as of April 24, 2022 (up from 69% on November 16, 2021). 76% of Americans age 18 and over are fully vaccinated (up from 71% on November 16, 2021). 90% of Americans over age 65 are fully vaccinated (up from 86% on November 16, 2021), indicating a promising way forward for the most at-risk population.

CDC AUTHORIZED COVID-19 BOOSTER VACCINES

CDC guidance on COVID-19 Booster Vaccines stated that Americans eligible for a second booster shot include adults ages 50 years and older, people ages 12 years and older who are moderately or severely immunocompromised, and people who received 2 doses (1 primary dose and 1 booster) of Johnson & Johnson's Janssen vaccine. Currently, the three vaccines that are authorized and recommended to prevent COVID-19 by the CDC arePfizer-BioNTech COVID-19 vaccine,Moderna COVID-19 vaccineandJohnson & Johnson's Janssen COVID-19 Vaccine.

METHODOLOGYThis Long Island University Steven S. Hornstein Center for Policy, Polling, and Analysis online poll was conducted through SurveyMonkey from April 21 22, 2022 among a national sample of 1,584 adults ages 18 and up. Respondents for this survey were selected from over 2.5 million people who take surveys on the SurveyMonkey platform each day. Data for this week have been weighted for age and gender using the Census Bureau's American Community Survey to reflect the demographic composition of the United States. The modeled error estimate for this survey is plus or minus 2.5 percentage points.

ABOUT THE LONG ISLAND UNIVERSITY STEVEN S. HORNSTEIN CENTER FOR POLICY, POLLING, AND ANALYSISThe Long Island University Steven S. Hornstein Center for Policy, Polling, and Analysis conducts independent polling, empirical research, and analysis on a wide range of public issues. Our studies inform the public and policy makers about critical issues, attitudes, and trends shaping the world. Visit liu.edu/Hornstein for more information and results from this national poll.

ABOUT LONG ISLAND UNIVERSITYLong Island University, founded in 1926, continues to redefine higher education, providing high quality academic instruction by world-class faculty. Recognized byForbesfor its emphasis on experiential learning and by the Brookings Institution for its "value added" to student outcomes, LIU has a network of over 285,000 alumni, including industry leaders and entrepreneurs around the globe. Visit liu.edu for more information.

SOURCE Long Island University

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Where Americans Stand on Coronavirus and Mask Mandates on Planes: Long Island University Hornstein Center National Poll - PR Newswire

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Covid News: At Least 53 People Test Positive After A-List Dinner in Washington – The New York Times

Posted: at 5:27 pm

A checkpoint in Ningbo, China. A growing number of Chinese cities are requiring truck drivers to take daily Covid P.C.R. tests.Credit...Agence France-Presse Getty Images

BEIJING Chinas mounting Covid-19 restrictions are creating further disruptions to global supply chains for consumer electronics, car parts and other goods.

A growing number of Chinese cities are requiring truck drivers to take daily Covid P.C.R. tests before allowing them to cross municipal borders or are quarantining drivers deemed to be at risk of infection. The measures have limited how quickly drivers can move components among factories and goods from plants to ports.

Shanghai and other major Chinese cities have imposed lengthy, stringent lockdowns to try to control Covid outbreaks. Previous interruptions in the supply of goods from Chinese factories to buyers around the world mainly involved the temporary closure of shipping ports, including in Shenzhen in southeastern China in May and June last year and then near Shanghai last summer.

The problem is not ships its that theres no cargo coming because there are no trucks, said Jarrod Ward, the chief East Asia business development officer in the Shanghai office of Yusen Logistics, a large Japanese supply chain management company.

The testing of truck drivers has been held up because some cities are doing mass testing of residents. Shanghai tested essentially all 25 million people within its borders in a single day on Monday and detected another 21,000 cases on Thursday.

Now, there is an acute shortage of truck drivers in Shanghai and in nearby cities like Kunshan, a center of electronics production. Many electronics components manufacturers are shutting down in Kunshan.

The key electronics suppliers to Apple, to Tesla, theyre all based there, said Julie Gerdeman, the chief executive of Everstream, a supply chain risk management affiliate of DHL that is based in San Marcos, Calif.

Apple declined to comment, and Tesla had no immediate reply to questions.

Many factories have tried to stay open by having workers stay on site instead of going home. Employees have been sleeping on mats on the floor for as long as four weeks in some cities in northeastern China. Companies have been storing goods in nearby warehouses while waiting for normal truck traffic to resume.

But as lockdowns stretch on in cities like Shanghai, Changchun and Shenyang, factories are starting to run out of materials to assemble. Some are sending their workers home until further notice.

Making car seats, for example, requires different springs, bolts and other materials. Mr. Ward said car seat producers had run out of components. Volkswagen said it had closed a factory outside Shanghai.

While Shanghais cases increase, its main rival in electronics manufacturing, Shenzhen, has emerged from lockdown. That is freeing workers and factories there to resume full-speed production.

Retailers and manufacturers in the West tried to adapt to previous supply chain difficulties in China by switching from ships to airfreight, but airfreight rates have more than doubled from last year.

The near-total suspension of passenger flights in and out of Shanghai has roughly halved the airfreight capacity there, said Zvi Schreiber, the chief executive of Freightos, a freight booking platform. The war in Ukraine has forced many airlines to schedule longer flights around Russia and Ukraine, which means each plane can make fewer trips in a week and often can carry less weight on each flight.

The war in Ukraine is also starting to hurt the availability of Soviet-era Antonov freighters, Mr. Schreiber said. These workhorses of the airfreight industry have been kept going in recent years almost entirely by Ukrainian maintenance bases that are now closed.

For companies, any additional disruptions to the global supply chain would come at a particularly fraught moment, on top of rising prices for raw materials and shipping, along with extended delivery times and worker shortages.

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Covid News: At Least 53 People Test Positive After A-List Dinner in Washington - The New York Times

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