Monthly Archives: August 2021

MGH team shows how injured muscles might be repaired with patients’ own skin cells – FierceBiotech

Posted: August 22, 2021 at 3:55 pm

Several years ago, researchers at Massachusetts General Hospital (MGH) figured out a way to convert skin cells into muscle cells that were self-renewing and seemed promising for treating injuries and degenerative diseases like muscular dystrophy. But they werent quite sure how the conversion was happening.

Now they knowand they believe their insights could yield recipes for generating patient-matched muscle cells to treat a range of disorders.

The MGH researchers call their muscle cells myogenic progenitor cells (iMPCs). In a new study, published in the journal Genes & Development, they explain how adding three chemicals to skin cells causes them to transform into iMPCs.

A gene called MyoD can convert skin cells into muscle cells, but mature muscle cells cannot divide to create new muscle. In previous experiments, the researchers hit on three chemicals that could make skin cells revert to a stem-cell-like state instead, which would allow them to transform into self-renewing muscle cells.

The key, the MGH researchers discovered in the new study, is that the chemicals remove marks called methyl groups that are added to DNA in a process known as DNA methylation.

DNA methylation typically maintains the identity of specialized cells, and we showed that its removal is key for acquiring a muscle stem cell identity, said lead author Masaki Yagi, Ph.D., a research fellow at MGH, in a statement.

RELATED: Zebrafish reveal regenerative protein that could inspire new treatments for muscle-wasting diseases and aging

Its the latest study focused on finding new ways to regenerate muscle. Earlier this year, an Australian team reported that a protein called NAMPT could regenerate muscle in zebrafish and mouse models by amplifying a natural healing process in the body that occurs when macrophages migrate to injury sites.

Other research groups have focused on the role of the MyoD protein in healing. A Sanford Burnham Prebys team, for example, discovered that in aging people, old muscle stem cells can trigger a DNA damage response that blocks MyoD and prevents muscle cells from forming.

The MGH scientists believe their findings could be useful beyond muscle regeneration. The three-chemical cocktail could be used to generate stem cells for a variety of tissue types, senior author Konrad Hochedlinger, Ph.D., a principal investigator at the Center for Regenerative Medicine at MGH and a professor of medicine at Harvard Medical School, said.

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GGRAsia Some non-gaming at Macau resorts still shut as of Thurs – GGRAsia

Posted: at 3:53 pm

Aug 19, 2021 Newsdesk Latest News, Macau, Top of the deck 

A number of non-gaming facilities, mostly involving catering, at some Macau casino resorts remained shut as of Thursday, despite the citys government lifting from Wednesday its two-week ban on operation of certain entertainment venues excluding casinos as a countermeasure against the risk of spreading the Delta variant of Covid-19.

That restriction had been brought in after four locals were found earlier this month to have been infected with that strain, leading to mass testing of those present in Macau. At that time, some of the citys casino operators had paused not only facilities that had been covered by the initial government order, but also some other non-gaming venues. The move coincided with a slump in tourism numbers during the Delta-variant alert.

A number of outlets mostly restaurants in some of these casino resort properties is still shut for the time being, according to GGRAsias review of announcements on the respective websites of the citys casino resorts. But some of these properties have flagged that their dining facilities will gradually resume operations.

Daily visitor numbers to Macau have remained low in the past fortnight, relative to the modest recovery seen in the spring and early summer.

But Macaus six casino operators have seen key non-gaming attractions reopened at their venues, including various spas, gymnasiums, beauty salons, swimming pools, and bars.

The properties with such notifications include: Grand Lisboa Palace and Grand Lisboa, promoted by SJM Holdings Ltd; MGM Macau and MGM Cotai, promoted by MGM China Holdings Ltd; Wynn Macau and Wynn Palace, promoted by Wynn Macau Ltd; Galaxy Macau, run by Galaxy Entertainment Group Ltd; the Venetian Macao and the Londoner Macao on Cotai, as well as Sands Macao on Macau peninsula, promoted by Sands China Ltd; and City of Dreams, and Studio City, promoted by Melco Resorts and Entertainment Ltd.

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19-year-old student loses RM37,000 in Macau scam – The Star Online

Posted: at 3:53 pm

IPOH: A 19-year-old student here was cheated of about RM37,000 in a purported Macau scam.

Jay Ng said he received a phone call, supposedly from Telekom Malaysia, on Friday (Aug 13) alleging that his mobile number was being used in an illegal gambling activity in Seremban.

Ng said he was told to lodge a report with the Seremban police, and was given a number of the district police station, which he later found out had been spoofed.

"I checked the number on the Internet to verify its authenticity.

"As the same number was shown, I then believed the matter to be true and started to get worried," he told a virtual press conference held by Perak MCA public service and complaints bureau chief Low Guo Nan on Tuesday (aug 17).

"A man, claiming to be one Asst Comm Datuk Hafiz, said he could help clear my name, but needed me to deposit some money first," he added.

Ng said he first transferred RM20,000 to a bank account belonging to one "Mohd Nasrullah".

"I was then told to transfer RM11,800 to a different account under 'Ramly Ab Hamid', and another RM5,000 to the same account," he said.

"Having almost cleared my bank account, I was asked for more and to borrow from friends or relatives.

"I then informed my father who told me to stop what I was doing as he believed that I had been scammed," said Ng, who added the money was inherited from his late mother for him to further his studies.

"I am aware of scam cases, but did not think that they would use a police station's number," said Low, who added people should always be vigilant.

"First, the people should never panic, and to go to the nearest police station to verify the matter.

"They should never ever reveal bank accounts and online banking details to strangers," said Low, who added that subsequent checks with the Semak MULE portal (a list maintained by the police commercial crime investigation department) found both accounts to be listed there.

"Why weren't the accounts frozen and are still actively being used by the syndicates?

"I hope the relevant authorities will work together to fight against these crimes that are getting rampant," he said.

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Crime increased 26% during the first half of 2021 – Macau Daily Times

Posted: at 3:53 pm

The number of crimes reported in Macau during the first half of this year (H1) rose by 26.1%, official statistics released yesterday by the Secretariat for Security show.Topping the list of incidents are cybercrimes, which registered a growth of 382% when compared with the same period last year.In the first half of 2021 the number of cybercrimes recorded reached 617 incidents 489 more than in 2020.Also growing significantly was criminal activity that facilitated illegal immigration, which rose 81.9% year-on-year from 182 cases in 2020 to 331 reported this year.Also on the rise were cases of sexual assault committed against underage people, which doubled from two to four this year.Scams and document forgery also contributed to the H1 spike in 2021. Both crimes grew by about 50%, while the crime of making false declarations to the authorities rose by 65%.By contrast, crimes that have traditionally been linked to casinos have reduced due to border restrictions related to the Covid-19 pandemic. The crime of kidnapping fell by 41.4%, the unlawful use of ID belonging to a third-person fell by 76.6%, and the distribution of forged currency by 19.4%.Violent crimes committed against individuals, including rape and sexual assault, were highlighted for their statistical increase in H1. The number of reported rapes increased by 23.1% to a total of 16 in the first half of 2021 three more cases than in 2020.In the report, the Secretary for Security, Wong Sio Chak, noted the increase in the number of incidents, but nonetheless expressed satisfaction with the fact that, in general, violent crimes have recorded a slight decrease of 0.8% y-o-y.Wong also noted that, since the numbers of the gaming industry remained low for the first half of this year, the Secretary has not conducted a specific analysis of criminality related to the industry, as was usual in crime reportage before the pandemic.

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Covid-19 | Footprint records on health code soon to become reality – Macau Daily Times

Posted: at 3:53 pm

LeaveHomeSafe, a digital contact tracing app launched by the Hong Kong Government

A footprint tracing function, endorsed by the Personal Data Protection Office, will likely be introduced to the Health Code system soon, Dr Leong Iek Hou, coordinator of the Center for Disease Control and Prevention, said at the regular health press conference yesterday.She added that the addition of the function to the platform is now in progress, and she anticipates its forthcoming roll-out.Regarding personal data security concerns, the public health doctor stressed that no data will be uploaded to any shared server owned or operated by the government. She said that the function will operate in such a way that data recorded will only be stored on the mobile device of the user.Similar to the footprint functions used in Hong Kong, Taiwan and Mainland China, users are required to scan a QR code posted at various if not all public venues to develop records of their movements.Leong did not explain how follow-up operations will be conducted. Given precedents set by the aforementioned territories, text messages are likely to be sent to users who have been to the same venues visited by a patient to notify them of any precautionary measures that need to be taken.The function has become increasingly anticipated by certain members of the public, as the four newest patients in the city were not able to clearly recall their movements in the days preceding their diagnosis.On another topic, Leong asked the public to update their addresses on the health code platform. She blamed users with incorrect addresses registered for putting extra workloads onto the Health Bureau during this time of intense epidemic control.Because of a non-updated address, they had their health code turned to red, and they [then] pushed to have the code corrected, which at the end of the day put a heavier burden to our team, Leong recalled.

No mass events allowedLeong referred to epidemiology to justify the current policy that no mass event can be held for the time being, as Macau is still not completely safe from new contagion or even outbreaks.She stressed that Macau can only be considered totally safe when it achieves zero new cases for 28 consecutive days.However, this does not mean that the 28-day target is an immovable threshold. The consideration should take into account the impact on economic performance, she said.A similar scenario took place last year when the government stressed that the risks of outbreaks were still high, but gave green lights to the Food Festival and the Grand Prix.

DSEDJ undecided on school year startWith most schools having set their school year start between September 1 and 6, and as mass gatherings and events are discouraged by the health authorities, there may be an as yet unannounced delay on the commencement of the new academic year.Wong Ka Ki, head of the Education and Youth Development Bureaus Non-Tertiary Education Department, said at the press conference that guidelines regarding the matter have been distributed to schools.Cross-border students will be allowed to begin their new school year several days later than normal, Wong added.

Case of Bells palsy recordedHealth authorities reported another adverse events following immunization (AEFI)yesterday as a 31-year-old man suffered from Bells palsy after being administered with the second dose of Sinopharm vaccine.The man received his second jab on August 12 and reported his case on August 18.In April, three residents also suffered from Bells palsy after being inoculated with Covid-19 jabs.

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A Sitcom Based on ESPN College Football Analyst Paul Finebaum Might Be Coming to Your TV – Sportscasting

Posted: at 3:51 pm

Sports mediapersonalityPaul Finebaumis one of the biggest and most well-known radio hosts in all of college football. In his 20 years of hosting his own show, Finebaum has been the center of the sports universe, especially in thegames epicenter of the SEC. While he just signed a new deal to continue his Charlotte-based show for ESPN, he also recently shared that there is a TV sitcom in the works about his life.

Finebaum graduated from theUniversity of Tennesseein 1978 and moved to Birmingham, Alabama, in 1980, perESPN. He became a columnist and reporter for theBirmingham Post-Heraldand theMobile Press-Register. The Memphis native also hosted thePaul Finebaum Radio Networkfrom 2001 to 2012, becoming the Voice of the SEC.

He jumped to ESPN in 2013 as the host ofThe Paul Finebaum Showand has helped anchor the networks college football coverage ever since. In July 2021, he signed a new multi-year extension withESPN.

The Mouth of the South is maybe most famous for a single call-in to his radio show in 2011. After someone poisoned Auburns famous Toomers Corner trees, an Alabama fan named Harvey Updyke using the pseudonym Al from Dadeville called into Finebaums show and admitted to the crime. He capped his admission with, Roll Damn Tide.

Finebaums radio show is also known for a host of colorful, college football-loving regular callers over the years. This includes the Alabama-loving Phyllis, Jim from Tuscaloosa, Darriel from Columbus, and the lateAuburnsuperfan Tammy.

Finebaum joinedThe Tony Kornheiser Showpodcast and shared that a sitcom is in the works based on the college football host. The opportunity arose when Finebaum taped an episode of his podcast at Kornheisers old restaurant, Chatter:

A producer in Hollywood heard the podcast. He called another guy, and two years later, this thing goes into motion, and its developed as a sitcom. It is sold to ABC. Its a takeoff of just like your show many years ago went to Hollywood, the guy who was going to play me is a younger person, Jason Biggs, the star of theAmerican Pieseries. And then COVID happened, and everythings up in the air.

They wrote it as a guy from New York who comes to the South, loosely set in Birmingham, Finebaum explained in more detail toAlabama.com. Someone with that mentality dealing with a different culture. Thats the concept. One of the ideas was to have me married to a very Southern family. And, just the conflicts of a New Yorker who was edgier than the norm.

The Kornheiser connection to Finebaums sitcom is twofold. In addition to the podcast taping that caught the ABC execs attention being at Kornheisers studio, the sitcom sounds a lot like a short-lived sitcom based on Konrheisers life that aired for one season in 2004-05.

Listen Up!was a show that aired on CBS and starred Jason Alexander fromSeinfeldas Tony Kleinman (based on Kornheiser) and focused on his family life and his job hosting a sports debate show with his partner Bernie Widmer, aMichael Wilbon-type character played by Malcolm Jamal-Warner ofThe Cosby Showfame.

Sitcoms about sports have a checkered record of success on TV. Shows about sports media have a particularly tough time succeeding. In addition toListen Up!,My Boys, about a female sportswriter looking for love in Chicago, ran for four seasons on TBS to mediocre ratings. Even Aaron Sorkins critically-acclaimedSports Night, based onSportscenters Dan Patrickand Keith Olbermann, only made it two seasons.

However, several sports-themed sitcoms have succeeded through the years. Craig T. Nelsons college football-basedCoachran for nine seasons, and Mark Currys high school basketball-centricHangin With Mr. Cooperwent five seasons, both on ABC.

GLOW, about the 80s female wrestling league, ran three seasons on Netflix before COVID-19 concerns ended the fourth and final season filming. In 2021,Ted Lasso,about an American football coach learning English footballon Apple TV+, is one of the buzzed-about sitcoms of the year. Recent years have brought edgier sports sitcoms to TV. This group includes FXsThe League, IFCsBrockmire, and HBOsEastbound and DownandBallers.

If the Finebaum sitcom ever gets off the ground, it seems like it will fall into the former category of sports media shows that dont go very far. That said, ABC has a solid history of making these types of shows work, so if Finebaum is a success, it wont be a complete surprise.

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RELATED:Stephen A. Smith Crushes Mitchell Trubisky For Throwing Shade at the Bears: There Wasnt a Single Team That Wanted You as a Starter, Bro

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Before 2001 Invasion, Bush Admin Declared Taliban an Ally in the War on Drugs – Truthout

Posted: at 3:50 pm

Just months before the Taliban became an enemy in the war on terror, President George W. Bushs administration declared the fundamentalist rulers of Afghanistan an ally in the global drug war.

In early 2001, narcotics officials in the United States praised a ban on poppy cultivation instituted by the Taliban that appeared to wipe out the worlds largest crop of opium poppies in a years time, even as aerial images raised suspicions about large stockpiles of heroin and opium on Afghanistans northern border. Secretary of State Colin Powell announced a $43 million gift to the Taliban that was broadly seen as a reward for banning opium cultivation even as farmers were hammered by a drought. Poppies, which produce a sap used to make opium, heroin, and other painkillers, are one of the only Afghan crops that grow well during drought. Observers feared famine would grip the countryside. Meanwhile, critics of the Talibans harsh laws and brutal oppression of women and girls were furious at the Bush administration for supporting the regime.

Taliban leaders declared drug production a violation of Islamic law and promised farmers international aid. Farmers complied out of faith, obedience and fear of going to prison. However, the Talibans motives appeared to be anything but religious. Afghanistan was increasingly seen as a pariah state on the international stage, and the Taliban craved the legitimacy that came with support of the U.S. The ban also drastically inflated the price of opium, allowing the Taliban and other traffickers to liquidate existing stockpiles at a premium.

The ban marked the only time in modern history that any government has stopped poppy farming in Afghanistan, the worlds top supplier of plant-based heroin and opium. U.S. taxpayers spent $8.6 billion on eradication, counter-narcotics and alternative economic development campaigns, but opium production in Afghanistan soared during most of the U.S. occupation. Opium production increased by 37 percent between 2019 and 2020 alone, and the area under cultivation was one of the largest ever recorded, according to the United Nations. Like the global drug war, experts say the drug war in Afghanistan only made heroin and opium more lucrative for warlords and traffickers including the Taliban.

The drug war in Afghanistan was enmeshed within a larger nation-building project and plagued with the same corruption and cultural incompetency that ultimately doomed the $145 billion attempt at forcing the country to become a Western-style democracy. For years, the Special Inspector General for Afghanistan Reconstruction (SIGAR) has served as the governments watchdog and meticulously documented the unraveling of the U.S. mission in regular reports to Congress. In 2018, SIGAR reported that not a single counter-drug program undertaken by the U.S., the Afghan government or coalition allies resulted in a lasting reduction in opium production.

The Afghan anti-drug campaign also mirrored drug wars waged in countries such as Colombia, where U.S.-led efforts to eradicate coca devastated poor farmers and encouraged corruption but did little to snuff out cocaine production, according to Sanho Tree, the director of drug policy at the Institute for Policy Studies.

With the drug war and the war on terror, members of Congress dont tend to be vocal critics of these things, they always vote to support the troops and law and order, Tree said in an interview.

Tree and other experts argue that supply-side military and police interventions have never prevented people from selling and using drugs such as heroin and cocaine. A growing movement of activists and reformers say policymakers should focus on making drug use safer and providing resources to users instead. Today, the vast majority of Americans agree that the drug war has failed, and two-thirds say criminal penalties should be removed for all drugs, not just marijuana.

Tree said the Talibans opium ban backfired as the U.S. invaded in late 2001. The ban devastated rural areas suffering under severe drought, leaving farmers desperate for international relief. The price of opium plummeted as traffickers rushed to empty warehouses full of drugs before U.S. airstrikes and ground troops could reach them.

After the U.S. military overran the Taliban, farmers quickly planted opium again. The British military began paying farmers to destroy their opium crop, an eradication strategy that proved ineffective. Most of Afghanistans opium is sold in Europe and Asia, not the U.S., and the U.S. military was initially wary of undertaking a large-scale opium eradication effort. But by late 2003 it became clear that the Taliban and other insurgents raised revenue from narcotics, and drug trafficking was increasingly seen as a threat to stability. The U.S. appointed a drug czar for Afghanistan and took a lead role in counter-drug efforts, effectively launching a drug war within a military occupation.

Turning farmers away from opium was seen as crucial for establishing the stable, function democracy the U.S. envisioned. However, Tree said prohibition always drives up drug prices, and the crackdown boosted the value of opium for traffickers willing to risk being targeted by the U.S.-led coalition.

When President Bush went after their opium, he made it much easier for the Taliban to fund their war effort, Tree said. They would have to tax less opium to make more money, because the price went up.

Congress soon demanded action on opium, and by 2005, the State Departments narcotics division aggressively pushed the Afghan government to accept the aerial spraying of the crop-killing herbicide glyphosate on poppy fields. The State Departments plan sparked bitter opposition in the Afghan government and at the Department of Defense, which feared the spraying would turn the countryside against the U.S. coalition.

Tree has traveled to Colombia multiple times and observed the U.S.-sponsored aerial spraying campaign targeting coca farms, which he said fueled corruption and was largely ineffective. The U.S. and Colombian governments hoped to eradicate the cocaine supply for narco-traffickers and anti-government guerillas, but rural farmers were devastated and often turned against the government. The Colombian government suspended aerial spraying in 2015 after the World Health Organization declared glyphosate a probable human carcinogen.

What I saw on the faces of these farmers, the rage and frustration and anguish in their eyes, I will never forget, Tree said. What the hell am going to do now, how do I feed my children next week or next month or next year?

Aerial spraying never occurred on a large scale in Afghanistan, but the plan created deep divisions between the coalitions various counter-drug efforts and damaged relations with the Afghan political leadership for years, according to SIGAR. For the remainder of the occupation, debates raged between competing federal agencies, with military leaders arguing that opium eradication weakened counterinsurgency efforts to win hearts and minds. At the same time, drug trafficking and taxes on farmers were fueling the Talibans insurgency, and U.S. contractors and narcotics agencies wanted in on the action.

Under President Obama, the U.S. paused mandatory opium eradication without the consent of local and regional Afghan leaders. The U.S. poured millions of dollars into failed alternative development efforts to replace opium with another crop, but SIGAR reports that the programs lacked oversight and even encouraged opium farming in some cases. Tree said much of the funding was sucked up by military contractors and non-governmental organizations (NGOs) in a country where the economic and legal systems run on grift and bribes.

The money never reaches the people its supposed to reach, it reaches a lot of contractors with deep pockets and NGOs. The drug wars in Colombia and Afghanistan turned NGOs into a four-letter word, Tree said.

Opium production reached new heights in 2017, and the Trump administration began aerial strikes on suspected drug labs. More than 200 structures were destroyed across the Afghan countryside, but the bombing campaign once again proved the futility of fighting a war on drugs. Mud huts that housed drug labs were easily recreated elsewhere, and an independent forensic analysis concluded that the campaign achieved little besides putting civilian lives at risk and further alienating villagers as the Taliban campaign to retake the country intensified.

The U.S. Drug Enforcement Agency trained two Afghan law enforcement agencies to combat drug trafficking and organized crime, but the elite outfits failed to make a meaningful dent in the drug trade. The amount of opium seized by drug agents since 2008 amounts to only 8 percent of the opium produced in Afghanistan in 2019 alone, according to SIGAR. Lawmakers have taken note; funding from Congress for Afghan drug interdiction programs dwindled in recent years until finally reaching zero in 2021.

Tree compared the drug war in Afghanistan to the Afghan security forces that were trained by the U.S. but quickly folded as the Taliban rapidly took control of the country in the past week. The U.S. military and its contractors could report back to Washington that they successfully trained and equipped a certain number of soldiers, but in reality, many chose to strike amnesty deals with the Taliban rather than stay and fight.

What struck me was the metrics they use to monitor to report success in training the Afghan military are very similar to the bullshit metrics that drug warriors use, in that they want metrics that are easy to meet, that are divorced from reality and of little consequence, Tree said.

Such zombie metrics and a revolving door of contractors and personnel help, Tree said, explain why Congress continued funding drug war operations in Afghanistan even as they failed year after year. The global war on drugs has cost the U.S. $1 trillion over the past four decades; the war on Afghan opium alone has cost billions of tax dollars and failed to reduce the supply. Instead, it made the drug trade much more lucrative, which worked out well for the Taliban.

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The War On Drugs ‘Slave Ambient’ Review: Looking Back 10 Years Later – Stereogum

Posted: at 3:50 pm

It was a dense, lush sound, one in which you could always find new details but also one where the songs crystallized enough to pull you in right away. For me, the first time I heard Slave Ambient was one of the most random places possible. I had been studying abroad in Shanghai for a few months, and my brother who had just seen the War On Drugs open for the National in New York sent me a few YouTube links to check out. Thanks to a VPN we had installed to bypass Chinese firewalls, it was damn near impossible to load YouTubes, but when I finally heard these songs, I was floored. Maybe a month later, I tracked down a CD copy of Slave Ambient in Sydney, and probably paid something like 25 American dollars for it. (I was a stubbornly late abandoner of physical media.) For almost a week, I walked every inch of Sydney listening to this album, staring at Christmas decorations in the summer and oceans that were such an alien shade of blue they almost seemed psychedelic themselves. I was immersed in this sound, somehow a perfect soundtrack for ambling around a place as foreign and far-flung to me as Australia. But all along the way, Slave Ambient was really beckoning me back home.

For a young classic rocker, the War On Drugs were already easy to love. But for me, having grown up in small-town Pennsyvlania about 90 minutes north of Granduciels home in Philly, their sound felt like mine. In their music, I heard every train graveyard, every dead shopping mall, every collapsing coal breaker, every formerly opulent stone building left to decay in towns long since left behind. Many of Granduciels lyrics on Slave Ambient are little folk echoes, almost placeholders rollin and driftin, looking out past the rubble. Hes been up in the highlands, past the farms and debris. And in all that wreckage, he found something still living, enough that he could breathe a whole different array of colors into it. Driving around Pennsylvania listening to Slave Ambient, the fact that Granduciel could move through those same surroundings and find something new to be pulled up from the ground was more than enough to make you a fan it was inspiring.

It felt like I knew the sound of Slave Ambient somewhere deep down, but at the same time Granduciel articulated it in a way I couldve never imagined myself. Each time a grainy acoustic guitar ran up against a mutating loop, or his earthen voice sang above celestial synths, you could see the past and present and whatever came next mingling freely, a vibrant dream cohering where they all met.

Of course, thats long since become the calling card for the War On Drugs. Throughout, they have been described as classicist musicians tweaking not-exactly-enamored corners of rock history. When Slave Ambients successor Lost In The Dream arrived in 2014, Granduciel built on where hed been before but also crafted a whole new sound. More washed-out and bleary, at times more organic, but still existing in a Technicolor mist only he could see. And if people had tripped over themselves catching all the Springsteen and Dylan DNA on Slave Ambient, the next iteration of the Drugs really sent them reeling. Don Henley? Dire Straits? That whole stretch of years where Boomer musicians tried to keep up with the times, writing dusty rockers dappled with synthesizers? Really?

It was one of the least excavated parts of music history even in a time addled with nostalgic cycles and recurring resurrections. That has remained the path Granduciel has walked since, but at the same time there was always an undercurrent that felt, even as the band garnered runaway acclaim, uncharitable in drawing those comparison points. Granduciel was never exhuming corpses in another revival. From Lost In The Dream onwards, he took the Drugs into a space both watercolor and chiaroscuro, manipulating history to his own liking more than ever before.

And, bizarrely, it brought him greater and greater success. From the very first time we all heard the Woo! in Red Eyes, we knew we were in for something different musically on Lost In The Dream. What was impossible to predict, even then, was the implausible skyrocketing rise of this band matter-of-fact Philly guys playing in a working-class rock tradition turned cosmic, steadily climbing up festival posters until they were Grammy winners and one of the only big new rock bands in an era when big new rock bands are not often a thing. In the wake of Lost In The Dreams true breakthrough, Granduciel signed a two-record deal with Atlantic. The second of those, I Dont Live Here Anymore, comes out in October and if the absolute bangers Granduciel previewed on Instagram last year are anything to go by, it may take the War On Drugs ever further into the stratosphere.

For years, I used to hang on Slave Ambient, this gorgeous and transfixing document of when I first found this new strange sound from this scrappy Philadelphia band. I used to hold it up alongside the much more towering records that followed. But now, revisiting it on the other side of all that, you do have to yield a bit, admit that as wholly unique as Slave Ambient was in its time, it now doesnt quite compare to the peaks Granduciel has scaled since. Its more elusive, more straight-up druggy, without the precise yet blurred balance Granduciel has struck between sharp songcraft and madman sonic wizardry on the subsequent two albums. All these years later, it almost feels more appropriate to group Slave Ambient alongside Wagonwheel Blues as the prologue, the build-up to the War On Drugs becoming what they were supposed to be. Its still a rich, entrancing prologue, but a prologue all the same. Eventually, out past the rubble and up from the waves of ambience, a Woo! would ring out, and there would be no looking back.

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How the Global Drug War’s Victims Are Fighting Back – PRESSENZA International News Agency

Posted: at 3:50 pm

Despite significant advances made by governments around the world in humanizing drug control systems since the turn of the century, human rights abuses still seem to be taking place in the course of enforcing drug prohibitions in recent years and, in some cases, have only gotten worse.

By Phillip Smith

The United States continues to imprison hundreds of thousands of people for drug offenses and imposes state surveillance (probation and parole) on millions more. The Mexican military rides roughshod over the rule of law, disappearing, torturing, and killing people with impunity as it wages war on (or sometimes works with) the infamous drug cartels. Russia and Southeast Asian countries, meanwhile, hold drug users in treatment centers that are little more than prison camps.

A July virtual event, which ran parallel to the United Nations High-Level Political Forum on Sustainable Development, shined a harsh light on brutal human rights abuses by the Philippines and Indonesia in the name of the war on drugs and also highlighted one method of combating impunity for drug war crimes: by imposing sanctions.

The event, SDG 16: The Global War on Drugs vs. Rule of Law and Human Rights, was organized by DRCNet Foundation (a sister organization of the Drug Reform Coordination Network/StoptheDrugWar.org), a U.S.-based nonprofit in consultative status with the UN Economic and Social Council. The SDG 16 refers to Sustainable Development Goal 16Peace, Justice, and Strong Institutionsof the UNs 2030 Agenda for Sustainable Development.

Event organizer and DRCNet Foundation executive director David Borden opened the meeting with a discussion about the broad drug policy issues and challenges being witnessed on the global stage.

Drug policy affects and is affected by many of these broad sustainable development goals, he said. One of the very important issues is the shortfall in global AIDS funding, especially in the area of harm reduction programs. Another goalPeace, Justice, and Strong Institutionsis implicated in the Philippines, where President [Rodrigo] Duterte was elected in 2016 and initiated a mass killing campaign admitted by himalthough sometimes denied by his defendersin which the police acknowledged killing over 6,000 people in [anti-drug] operations [since 2016], almost all of whom resisted arrests, according to police reports. NGOs put the true number [of those who were] killed at over 30,000, with many executed by shadowy vigilantes.

The International Criminal Court (ICC) has proposed a formal investigation of human rights abuses in the Philippines drug war, but the court seems hampered by a chronic shortfall in funding, Borden pointed out.

Former prosecutors have warned pointedly on multiple occasions of a mismatch between the courts mission and its budget, he said. Recent activity at the conclusion of three different preliminary investigations shows that while the prosecutor in the Philippines moved forward, in both Nigeria and Ukraine, the office concluded there should be formal investigations, but did not [submit] investigation requests, leaving it [up to the] new prosecutors [to do so]. The hope is [that the ICC] will move as expeditiously as possible on the Philippines investigation, but resources will affect that, as will the [Philippine] governments current stance.

The governments current stance is perhaps best illustrated by President Dutertes remarks at his final State of the Nation address on July 26. In his speech, Duterte dared the ICC to record his threats against those who destroy the country with illegal drugs, the Rappler reported. I never deniedand the ICC can record itthose who destroy my country, I will kill you, said Duterte. And those who destroy the young people of my country, I will kill you, because I love my country. He added that pursuing anti-drug strategies through the criminal justice system would take you months and years, and again told police to kill drug users and dealers.

At the virtual event, Philippines human rights attorney Justine Balane, secretary-general of Akbayan Youth, the youth wing of the progressive, democratic socialist Akbayan Citizens Action Party, provided a blunt and chilling update on the Duterte governments bloody five-year-long drug war.

The killings remain widespread, systematic, and ongoing, he said. Weve documented 186 deaths, equal to two a day for the first quarter of the year. Of those, 137 were connected to the Philippine National Police, the Philippine Drug Enforcement Agency, or the armed forces, and 49 were committed by unidentified assailants.

The unidentified assailantsvigilante death squads of shadowy provenanceare responsible for the majority of killings since 2016.

Of the 137 killed, 96 were small-time pushers, highlighting the fact that the drug war is also class warfare targeting small-time pushers or people just caught in the wrong place or wrong time, Balane said.

He also provided an update on the Duterte administrations response to ICC Prosecutor Fatou Bensoudas June 14 decision concluding her preliminary examination of human rights abuses in the Philippine drug war with a request to the ICC to open a formal investigation into the situation in the Philippines.

In a bid to fend off the ICC, in 2020, the Philippine Justice Department announced it had created a panel to study the killings carried out by agents of the statepolice or militarybut Balane was critical of these efforts.

[In the second half of 2020], the Justice Department said it had finished the initial investigations, but no complaints or charges were filed, he said. They said it was difficult to find witnesses [who were willing to testify about the killings], but [the victims] families said they were not approached [by the review panel].

The Justice Department is also undercutting the Philippine Commission on Human Rights, an independent constitutional office whose primary mission is to investigate human rights abuses, Balane pointed out.

The Justice Department said the commission would be involved [in the investigation process by the panel], but the commission says [that the] Justice [Department] has yet to clarify its rules and their requests have been left unanswered, Balane said. The commission is the constitutional body tasked to investigate abuses by the armed forces, and they are being excluded by the Justice Department review panel.

The Justice Department review is also barely scraping the surface of the carnage, Balane said, noting that while in May the Philippine National Police (PNP) announced they would be granting the review panel accessto 61 investigationswhich accounts for less than 1 percent of the killings that the government acknowledged were part of the official operations since 2016the PNP has now decreased that number to 53.

The domestic review by [the] Justice [Department] appears influenced by Duterte himself, said Balane. This erodes the credibility of the drug war review by the Justice Department, which is the governments defense for their calls against international human rights mechanisms.

The bottom line, according to Balane, is that the killings continue, they are still systematic, and they are still widespread.

In Indonesiawhere, like Duterte in the Philippines, President Joko Widodo (Jokowi) also declared a war on drugs in 2016it is not only extrajudicial killings that are the issue but also the increasing willingness of the government to resort to the death penalty for drug offenses.

Extrajudicial killings [as a result of] the drug war are happening in Indonesia, said Iftitah Sari, a researcher with the Indonesian Institute for Criminal Justice Reform, who cited 99 extrajudicial killings that took place in 2017 and 68 that happened in 2018, with a big jump to 287 from June 2019 through June 2020. She also mentioned another 390 violent drug law enforcement incidents that took place from July 2020 through May 2021, of which an estimated 40 percent are killings.

The problem of extrajudicial killings [in Indonesia] is broader than [just] the war on drugs; we [also] have the problem of police brutality, Sari said. Police have a very broad authority and a lack of accountability. There is no effective oversight mechanism, and there are no developments on this issue because we have no mechanisms to hold [the] police accountable.

Indonesia is also using its courts to kill people. Since 2015, Sari reported, 18 people15 of them foreignershave been executed for drug offenses.

In addition to extrajudicial killings, there is a tendency to use harsher punishment, capital punishment, with the number of death penalties rising since 2016, she said.

Statistics Sari presented bore that out. Death penalty cases jumped from 22 in 2016 to 99 in 2019 and 149 in 2020, according to the figures she provided during the virtual event.

Not only are the courts increasingly handing down death sentences for drug offenses, but defendants are also often faced with human rights abuses within the legal system, Sari said.

Violations of the right to a fair trial are very common in drug-related death penalty cases, she said. There are violations of the right to be free from torture, not [to] be arbitrarily arrested and detained, and of the right to counsel. There are also rights violations during trials, including the lack of the right to cross-examination, the right to non-self-incrimination, trial without undue delay, and denial of an interpreter.

With authoritarian governments such as those in Indonesia and the Philippines providing cover for such human rights abuses in the name of the war on drugs, impunity is a key problem. During the virtual events panel discussion, Scott Johnston, of the U.S.-based nonprofit Human Rights First, discussed one possible way of making human rights abusers pay a price: imposing sanctions, especially under the Global Magnitsky Act.

That U.S. law, originally enacted in 2012 to target Russian officials deemed responsible for the death of Sergei Magnitsky in a Russian prison, was expanded in 2016 to punish human rights violators around the globe by freezing their assets and denying them visas to enter the United States.

In an era [when] rising human rights abuses and also rising impunity for committing those abuses [are] a hallmark of whats happening around the world, we see countries adopting these types of targeted human rights mechanisms [imposing sanctions] at a rate that would have been shocking even five or six years ago, said Johnston. Targeted sanctions [like the Global Magnitsky Act] are those aimed against specific individual actors and entities, as opposed to countrywide embargos, he explained.

The Global Magnitsky program is one such mechanism specifically targeted at human rights abuses and corruption, and the United States has imposed it against some 319 perpetrators of human rights abuses or corruption, Johnston said. (The most recent sanctions imposed under the act include Cuban officials involved in repressing recent protests in Cuba, corrupt Bulgarian officials, and corrupt Guatemalan officials.)

Weve seen a continued emphasis on using these tools in the transition to the Biden administration, with 73 cases [of sanctions having been reported] since Biden took office, he noted.

And it is increasingly not just the United States.

The U.S. was the first country to use this mechanism, but it is spreading, Johnston said. Canada, Norway, the United Kingdom, [and] the European Union all have these mechanisms, and Australia, Japan, and New Zealand are all considering them. This is a significant pivot toward increasing multilateral use of these mechanisms.

While getting governments to impose targeted sanctions is not a sure thing, the voices of global civil society can make a difference, Johnston said.

These are wholly discretionary and [it] can be difficult to [ensure that they are] imposed in practice, he said. To give the U.S. government credit, we have seen them really listen to NGOs, and about 35 percent of all sanctions have a basis in complaints [nonprofits] facilitated from civil society groups around the world.

And while such sanctions can be politicized, the United States has imposed them on allied countries, such as members of the Saudi government involved in the killing of U.S.-based journalist Jamal Khashoggi and in cases of honor killings in Pakistan, Johnston noted.

But we still have never seen them used in the context of the Philippines and Indonesia.

Maybe it is time.

This article was produced by Drug Reporter, a project of the Independent Media Institute.

Phillip Smith is a writing fellow and the editor and chief correspondent of Drug Reporter, a project of the Independent Media Institute. He has been a drug policy journalist for more than two decades. He is the longtime writer and editor of the Drug War Chronicle, the online publication of the nonprofit Stop the Drug War, and was the editor of AlterNets coverage of drug policy from 2015 to 2018. He was awarded the Drug Policy Alliances Edwin M. Brecher Award for Excellence in Media in 2013.

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In Afghanistan, it was a war financed by heroin – convergenceri.com

Posted: at 3:50 pm

PART Two

PROVIDENCE It may be a bit risky to write this story; by reading it, you risk becoming complicit in understanding that there are suppressed facts about the U.S. involvement with drug trafficking in Afghanistan, specifically about the production of opium and refining it into heroin, run by the Taliban and allegedly financed by the Pakistani intelligence service, its military and its banks, that has functioned as the financial linchpin of the 20-year war in Afghanistan waged by the U.S., far different from all sorts of false policy and political goals that have been used to rationalize our military presence.

It might be wiser to follow the directive of Irish poet Seamus Heaney, who in a poem about the troubles in Northern Ireland, offered the advice: whatever you say, say nothing.

So, yes, writing this story may prove to be risky; my best protection is having you read the story and then share it.

As detailed in PART One, Connecting the Sacklers, Afghanistan and addiction, ConvergenceRI offered a history lesson for those who still pretend to know nothing, recall nothing, and deny everything.

The I do not recall approach by the Sackler family is more than just a legal strategy; it is a refusal to take responsibility for their greed in making billions of dollars in pushing and pimping OxyContin, a highly addictive prescription painkiller. Bankuptcy appears to be a deliberate corporate strategy to evade legal and financial accountability for their actions.

R.I. Attorney General Peter Neronha remains one of nine state attorneys general still seeking to hold the Sacklers accountable.

The willful blindness of the Sackler family strikes a resonant chord with the similar I see nothing strategy of the U.S. military and the State Department in ignoring the heroin trafficking business of the Taliban, a tradition of corruption that dates back hundreds of years to the British East India Company in pursuing a global monopoly in pushing opium.

In PART Two, ConvergenceRI conducted an interview with Elizabeth Gould and Paul Fitzgerald, authors of Invisible History: Afghanistans Untold Story, as a way to better understand the history of drug trafficking of heroin by the Taliban in Afghanistan. Stephen Kinzer, the author of The Brothers, about John Foster Dulles and Allen Dulles, had recommended that ConvergenceRI speak with Gould and Fitzgerald. [They are also the authors of Crossing Zero: The Af/Pak War at the Turning Point of the American Empire.]

In their recent article, President Carter, Do You Swear To Tell the Truth, the Whole Truth, and Nothing But the Truth? Gould and Fitzgerald lay out the historical framework detailing the strategy of Carters National Security Advisor, Zbigniew Brzezinski, to launch a secret program, six months before the Russians invaded Afghanistan, in order to draw the Russians into the Afghan trap. [See link to story below.]

Here is the ConvergenceRI interview with Elizabeth Gould and Paul Fitzgerald, talking about the role of heroin trafficking as a geopolitical tactic of intelligence services in what Rudyard Kipling once described as the great game of espionage.

ConvergenceRI: Do you have any questions for me, about ConvergenceRI?GOULD: What brings you to this particular type of story?

ConvergenceRI: I am the editor and publisher of ConvergenceRI, which is a digital news platform published weekly every Monday morning, launched in September of 2013, that covers the convergence of health, science, innovation, technology, research, education, and community, attempting to break down the silos and report on stories across the artificial barriers, the silos, that exist in most news coverage.

I have covered extensively the opioid epidemic, with a focus on the recovery communitys efforts to fashion a different approach around harm reduction.

I have been covering the ongoing legal bankruptcy proceedings against the Sacklers, the family that owns the privately held Purdue Pharma, and their efforts to preserve their wealth by evading future liability from civil litigation.

It struck me what was missing from the stories about what was occurring in Afghanistan, as the U.S. military prepares to leave the country after 20 years of war, was he fact that the Taliban run a huge heroin trafficking operation, which is the basis of their finances, and have done so for years. The Taliban was producing 80 percent of all the heroin supply for Europe and Asia, controlling the growing of opium and its refinement into heroin.

But nowhere has that become part of the story about what went wrong in Afghanistan. There appears to be a similar kind of blindness, if that it the right term, regarding the foreign policy and strategy, about the reasons why we got into Afghanistan, and the role that the CIA had played in the early 1980s in supporting the insurgency against the Russian invasion.

The way I initially found out about the State Department/CIAs involvement was that when I lived in Washington, D.C., I was the editor of Environmental Action Magazine, and I had housemate who worked with the State Department/CIA in Pakistan, who was responsible for funneling weapons and money and who knows what else to the insurgent forces, including Osama Bin Laden in those days.GOULD: What year would that have been?

ConvergenceRI: That would have been 1981, 1982, 1983. He was back in the states in 1984.GOULD: Those were very hot years in that arena.

ConvergenceRI: I had reached out to Stephen Kinzer, because he has written a lot about the world that the CIA and the State Department had played in pushing an agenda overthrowing of governments, both in his book, Overthrow, and again, in The Brothers, looking at the strategic policies of the Dulles brothers.

I thought he might serve as an excellent source for this story. And he, in turn, referred me to you. So, that is how I got to from here to there, and here again.GOULD: Right, right.

FITZGERALD: You know, the whole drug thing is at the core of our new book, the story about the assassination of Adolph Dubs, the American Ambassador to Afghanistan, back in 1979.

GOULD: We got the impression from your note that you were trying to get more details about what happened back in the 1980s.

ConvergenceRI: What is the title of the new book?GOULD: Valediction. It is actually a memoir. But it does lay out of the history associated the drug trades effects on Ambassador Dubs trying to move the whole issue of the Soviet Union and the outcome of trying to stabilize the area.

The drug issue was really an underlying issue all along, but it has never been talked about.

ConvergenceRI: Why has it never been talked about? Is it blindness? Is it because too many people are making too much money?GOULD: It is notorious for basically financing the black projects for the intelligence community.

That is an underlying problem of the whole nature of illegal drugs. That is the BCCI [the Bank of Credit and Commerce International, headquartered in Karachi and London], you know, the Pakistani bank, which was the bank that basically was managing all the drug money during that era. They were the money launderers.

FITZGERALD: They werent the only ones. They were the best known ones. It got to be so lucrative that so many people, at a high level, knew about it, and they just were able to quash any investigation. There were a couple of good books that were written about BCCI.

ConvergenceRI: I am somewhat familiar with those. When I go back into the history, when you look at Vietnam, and you look at the CIA and Air America and the transportation of refined heroin coming out of Laos, you have during the 1980s, in parallel, all the investments that were being made in the Contras were all funded by cocaine trafficking, apparently underwritten by the CIA and the U.S. government.FITZGERALD: There was a major shift at the end of the Vietnam War for the drug industry from Southeast Asia to Southcentral Asia.

That was a major event that occurred. I am sure you have seen the movie, American Gangster. It showed the tail end of U.S. involvement there.

There was a movie made back in the 1980s, Air America, the guy who wrote that screenplay wrote it up beautifully, and then the studio bought it, paid him a million dollars, and told him, We want you to walk away from it.

They turned into a Robert Downey [romantic] fantasy with Mel Gibson.

So, there was very high-level stuff from the very beginning that has been going on in terms of [tamping] down on the real story about what is going on.

A couple of French journalists, back in the 1970s, wrote a very detailed book about how the drug trade was moving from Southeast Asia to Southcentral Asia. I am going to get some quotes; I will be right back.

GOULD: What I think, in terms of our analysis at this point, the drugs, basically, is about finance. No matter what, that is basically the purpose. And, of course, drug addiction is kind of a downstream effect.

You have to sell the drugs to get the money. And obviously, that is what happened.

But I think it is really the U.S. military role in basically facilitating all of the [drug trafficking] activities. That has been going on now for 20 years in Afghanistan.

That is part of the problem, that the [drug trafficking of heroin] is a function of the U.S. military.

ConvergenceRI: Can you assume that the U.S. military at the highest levels knew all about this?GOULD: I cannot say for the record that yes, everyone knew. That I do not know. But the fact that Paul brought up the movie, American Gangster, that was exactly what the point of the whole film was about. You know, that [Frank Lucas, the main character] had a contact in the military, which was helping him get the drugs he needed. That was the level that we are talking about.

How high up the food chain [did it go]? [Was it] on a need-to-know basis? I imagine that there were quite a few people who didnt want to know so they cant be held accountable.

FITZGERALD: We talked to Chuck Cogan, on a couple of occasions, who ran the operations for the CIA from 1979 to 1984 [serving as chief of the Near East and South Asian Division in the CIAs Directorate of Operations], and we asked him about the drug trafficking. He said, of course, there were drugs there; everyone knew that there were drugs there.

Cogan said that that wasnt their goal, and that wasnt what they were directly involved in. The Pakistani ISI [intelligence services] were the ones that were actually running the drugs in the 1980s.

They set up a trucking company, actually. A correspondent from TIME magazine who covered these wars told us, he said, Planes were never empty, flying in and out. They would bring the guns in and they would fly out the heroin.

GOULD: That was one of the functions of the military.

FITZGERALD: There was a woman, Mary McGrory, who was a columnist for The Boston Globe.

Early on, after the Soviets invaded Afghanistan in 1979, she wrote a column for The Boston Globe, in which she said: What is the United States doing supporting all these drug dealers in Afghanistan? Because that is what these so-called freedom fighters are really all about.

And that was one of the few commentaries that was ever written about it, and they started to call her out, saying that she wasnt in possession of her senses, and all kinds of things.

When the boom came down, it came down on us, too. We did a documentary in 1981, and we showed it at the Parker House, and some of the local media and some of the international media were there, too.

And, Theodore Eliot, who was the Ambassador to Afghanistan from the United States, from 1972 until 1978, he came to the event, and he was then the dean of the Fletcher School of Diplomacy at Tufts University, and he basically said, You are not allowed; who gave you permission to say this? Who gave you permission to actually show this part of the story? You are not allowed to do that.

Right in front of everybody, he embarrassed himself.

GOULD: That was at the end of 1981.

FITZGERALD: If any journalist came out and talked about anything other than the official story about what was really going on, which was basically a fabrication. Then, you know, you were not allowed to profit from your journalism any more.

GOULD: The drugs were always viewed as secondary issues, which was very convenient for keeping a secret, or for keeping it as something not to focus on, as Chuck Cogan said. They knew all about the drugs. But they werent personally involved during the Soviet occupation.

But that, of course, wasnt the case in Vietnam, during the Vietnam War, and it certainly wasnt the case during the last 20 years in Afghanistan.

ConvergenceRI: What questions, as a journalist, need to be asked as we move forward? What investigations need to be done? What should journalists be focusing on?GOULD: You are dealing with a problem and a level of corruption that is so total, that actually, the drug issue hasnt really come up, partly because there are so many other complete misrepresentations. And that is part of what our research has been about, being able to track the reality of how the Soviets ended up in Afghanistan, and the role that the Carter administration played.

Yes, so the drug aspect was part of it, there is definitely evidence, in fact, we can send you a paper that we wrote last year, about the Carter administrations active role, in guaranteeing that the Soviets were going to end up in Afghanistan, and ultimately, in what Zbigniew Brzezinski described as their own Vietnam.

The drug aspect is in there, too. It is the story about the Carter official who was trying to control the drugs, and was basically told by the Carter administration that he was not allowed to tinker with any of the issues around drugs. And, he was shot.

So, you have that kind of evidence, where there were officials who did not realize about what some of the underlying objectives were.

Those issues never seemed like the front-end issues. Because the politics, and the military-industrial complex, sucked up all the attention.

FITZGERALD: What you have to realize is that the British East India Company had a monopoly on the opium that they were shipping to China in 1775, before the United States was even a country. The [British] built their empire, Hong Kong was basically established as a banking empire to launder the drug money.

But the fact was, it wasnt illegal at the time. And even when it became illegal, it wasnt illegal because it was immoral, that they were destroying peoples lives, it was because they couldnt tax it.

That is the way that the DEA was setting it up under President Nixon. You had this whole evolution of the anti-drug people, the war on drugs and the creation of the Drug Enforcement Agency under Nixon, you got this whole process at work, it is like the evolution of an idea, using the cover of morality and the whole chemical thing that drug addiction does to people, but it is really about business, and it is a big business. And it is been around for a long time.

GOULD: The drugs were used to finance black projects, completely with dark money.

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