Daily Archives: August 14, 2021

Detectives see new promise in long-shelved DNA. But there are pitfalls. – Las Vegas Review-Journal

Posted: August 14, 2021 at 12:54 am

Little Hector Perez was hanging out on the baseball bleachers of Maslow Park with a group of about 15 kids when the car pulled up.

It was a calm, October night in 2001. The dark-colored Dodge Neon with four people inside rolled by at around 9:15 p.m. Someone pointed a gun out of a tinted, passenger window and opened fire.

The children scattered as roughly half a dozen bullets whizzed through the evening air. When they returned after the car left, they found 9-year-old Hector slumped over with a gunshot wound to his chest, police said. The fourth grader died at University Medical Center.

Witnesses did not get a good look at the shooter. Some did not talk to police. Investigators suspected gang involvement. About a month and a half later, then-homicide detective Sheila Huggins worried that the case would never be solved.

Random acts of violence are so hard to follow up, Huggins told the Las Vegas Review-Journal in November 2001.

Nearly 20 years later, the case remains open. It haunts Huggins to this day.

The cold case unit

Metros cold case unit is made up of five retired homicide detectives who work part-time on their pension to investigate unsolved killings, including Hectors.

Related: Inside Metros record-breaking cold case

Dan Long and Ken Hefner, who have been with the unit for 2.5 and 6 years, respectively, said there are common misconceptions about what makes a case cold. It does not get that distinction until the cases lead detective retires. Even then, another detective may choose to take it on until they retire.

As former homicide detectives, we know there are times where youre more of a fireman than a detective, Hefner said, describing working on cases that cropped up earlier in his career like putting out fires left and right.

The cold case unit affords its investigators more time to dig deep, allowing seasoned detectives with the instinct and training needed to solve a killing the freedom to work without the pressure of a constantly climbing caseload.

Still, as time passes, witnesses move or die. Memories can falter.

The most likely thing thats going to solve our cases is DNA, Long said.

And advancements in technology are giving decades-old samples new promise.

The promise of DNA

Last month, Las Vegas police announced that the cold case unit had identified a suspect in the 1989 strangulation of local teen Stephanie Isaacson using a mere 15 cells of DNA evidence. It set a world record for the smallest amount of DNA ever used to help solve a crime.

The same sample had been run several times over the years through a DNA database maintained by the FBI, but never saw a match. The latest lead came from genome sequencing, a type of DNA testing that utilizes family trees and shared DNA between relatives to help identify possible suspects. The same testing identified Californias since-convicted Golden State Killer in 2018.

Now, Metro cold case detectives think another development in DNA technology called phenotyping could help solve the 2004 slaying of Theresa Insana, a 26-year-old sales executive for the Rio who was killed in her Summerlin home.

Police at the time of Insanas death said there were no signs of forced entry at her house. Her car was still there and her purse, keys, credit cards and cocker spaniel puppy were all inside. Her remains were found a few miles away, near what was then a drainage culvert at Hualapai and Peace ways.

She was in her house minding her own damn business and somehow, somebody comes in and kills her, Hefner said. She was one of those truly innocent victims.

Carol Palazzo, Insanas cousin, says the family has fought tirelessly to find Insanas killer in the nearly two decades since her death. Insanas father died in April, but her mother still calls Metro every Monday, begging them not to forget about her baby girl.

Theyve looked into all kinds of leads, and theyve run the DNA, but nothing ever panned out and its been 17 years, Palazzo said. Its left a huge void in our family.

Critics have doubts

Proponents of phenotyping say it allows analysts to reverse-engineer a persons physical profile based on a DNA sample. Using the method, Metro has a composite image of what Insanas killer may have looked like.

CeCe Moore, chief genetic genealogist at Virginia-based Parabon NanoLabs, which offers a phenotyping service to law enforcement agencies, said phenotyping isnt used to create an exact image, but rather to provide a list of physical attributes that investigators like Hefner can use to narrow down their suspect search.

Some scientists, like Kenneth Kidd, are skeptical of the services credibility. Kidd, a retired Yale University genetics professor, said one of his main concerns is that Parabon NanoLabs research has not been published in peer-reviewed journals to validate its methods.

As a rigorous scientist, I just cant accept it, Kidd said.

Moore said Parabon NanoLabs hasnt published its work in a peer-reviewed journal because the company doesnt want to give out proprietary information.

Theyve spent a lot of money developing these predictions, and if you publish it in a peer-reviewed journal, youve just given away all of your trade secrets, Moore said, adding that the companys record of success speaks for itself.

Without divulging further details, Hefner said the phenotyping result has him confident Insanas case could be solved.

Limitations

Hectors case is harder. There was no physical contact from his killer.

Police did collect DNA evidence from an unspent cartridge found at the park. But a long-awaited match could only tell investigators who loaded the weapons magazine, not who fired the gun, bringing detectives right back to the drawing board.

The promise of DNA has its pitfalls, too.

You hope that someday, somebody will have the guts to say something, Huggins, the detective who originally worked Hectors case, said this month.

Following Hectors death, the little boys family held out hope that his killer would be found. His older brother, Robert Perez, was at the park when he was shot. He told the Review-Journal in November 2001 that he had trouble sleeping at night.

Hectors older sister, Cecilia Martinez, told the Review-Journal in 2002 that she was hopeful someone would come forward.

Its still hard to believe this happened, she said at the time. Its hard not seeing him every morning.

Attempts to reach the Perez family for this story were not successful.

Crime scenes from other cold cases have been lost to development, but Maslow Park still stands. A memorial marker was dedicated to Hector there on May 31, 2002 a plaque near the ball fields where he bled out. Even that is gone now, though. Removed or stolen, but never replaced.

Contact Alexis Ford at aford@reviewjournal.com or 702-383-0335. Follow @alexisdford on Twitter.

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Detectives see new promise in long-shelved DNA. But there are pitfalls. - Las Vegas Review-Journal

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First Look: How Neill Blomkamp’s ‘Demonic’ broke new ground with its virtual horror show – SYFY WIRE

Posted: at 12:54 am

When Neill Blomkamp set out to make his first horror film, there were a few things he knew for sure. He knew he wanted to work low-budget, he knew he wanted demonic possession to be part of the story, and he knew he wanted to push the envelope of filmmaking technology through the use of "real-time computer graphics." After several years of experimental filmmaking through his company Oats Studios, it was time to move some of that experimentation into the feature-length realm.

"This idea of using volumetric capture and real-time computer graphics was one of the primary reasons I wanted to make the film," Blomkamp told SYFY WIRE. "And because I knew we were making something along the lines of these low budget horror movies, when you combine the idea of wanting to do real-time computer graphics, and then you think of all of these horror movies, when you blend them, it's like: 'Well, let's use the trope of demonic possession, and then what happens with that if we put it into a computer-generated world, what would that look like?' So that started leading to thoughts like, maybe the person who is possessed is in a coma and they're using VR as a way to stretch their legs."

That marriage of technological intrigue and horror storytelling eventually became Demonic, Blomkamp's next feature film, which tells a mother-daughter story rooted in trauma, possession, and fear, with a technological bent that pushes it into science fiction territory. To make the sci-fi element pop, Blomkamp decided to make extensive use of volumetric capture technology, using dozens of cameras all working at once to create three-dimensional renderings of his stars that could then be placed inside the film's virtual world. It's still an emerging technique in the realm of feature filmmaking, and Demonic's virtual horrors made use of it more than any other film to date.

The result is a film laced with sequences that look unlike any other horror movie you'll see this year, as Blomkamp's characters walk through a haunting virtual landscape that, in reality, was represented by a massive cage-like structure of cameras in an otherwise empty room.

"I mean, definitely the most psychologically challenging was the volcap stuff," Blomkamp explained. "The volumetric capture was by far the hardest because the actors are basically in a cage with 260 4K cameras aimed at them, and it's the most unreal, totally synthetic environment you could put an actor in. Even for me, and for the VFX supervisor, I'm trying to picture them in the location that they're going to be in, and then from a technical standpoint, we have to move them through the location."

Shot last summer with a small cast and crew in British Columbia, Demonic tells the story of Carly (Carly Pope), a woman haunted by a traumatic experience in her past linked to her estranged mother Angela (Nathalie Boltt). That past comes calling again when Carly learns that Angela is not just in a coma, but being treated by a company that's testing a new experimental therapy that taps into Angela's brain. Though she's comatose, by putting on a special headset, Carly can actually venture into her mother's mindscape, making contact with the woman locked inside her own body. Once inside, though, Carly finds more than just an awkward reunion with the mother she'd left behind.

To create a clear division between the real world and the mindscape, Blomkamp envisioned a process in which every virtual reality sequence Carly enters would be done through "volumetric capture" or "volcap," which would create real-time, three-dimensional images of the actors as they moved through space. Those images would then be placed inside 3D renderings of real locations, creating a realistic depiction of the prototype virtual reality technology in the film's story. In the gallery below, you can see the step-by-step process of how this all unfolded, from the initial volcap process to early effects work to use a "virtual camera" to frame the scene. Then, finally, there's the finished shot.

To achieve the level of volcap he was looking for, Blomkamp and his team drafted Tobias Chen's company Volumetric Camera Systems, which had already been working at that point with productions including Another Life and Altered Carbon to create volcap scans of actors, often for pre-visualization purposes. When Blomkamp came calling, though, Chen knew he and his team would have to level up.

"When you're doing this kind of volumetric capture of these holograms, what you're doing is, you're doing 30 or 60 3D scans, every single second," Chen explained. "And it's a sequence of 3D scans, not just one 3D scan. And Neill wanted to do these volcap scans of all the actors for every single shutter in the movie. So you would have 3D data of the background and you'd have 3D data of the actors."

To create the backgrounds, producer Mike Blomkamp and his team went out to real physical locations and performed three-dimensional scans of those environments for use in the final product, while Chen and his team began working on the volcap stage for the actors. That's where things got especially tricky.

When you think about actors performing on a blank stage while a crew captures their work to be composited into a film later, you probably imagine something like Avatar or Benedict Cumberbatch crawling across a soundstage to play Smaug in The Hobbit. At this point in filmmaking history, audiences are used to stories of actors performing against nothing for motion capture, so they can be transformed into characters along the way. As Chen explains it, though, volumetric capture is another matter.

"They have the actor wear these mocap suits or put these dots all over their body. And it uses cameras to track only those points. What we did in Demonic is we're not only tracking points, but we're tracking every single pixel on every single point on them. It's tracking every possible thing that the cameras captured, then computing that into a 3D model," Chen said. "So you're not only capturing the movements like you are in Avatar, but you're capturing all the textures, all the geometry, all the clothes, hair, everything all at once. So it's more like you're capturing a hologram of a person rather than just capturing their motions and then applying those motions onto a CG character."

That need to capture everything all at once means that the actor needs to be surrounded by a large framework of cameras, all working at the same time. Because camera resolution naturally works best if an actor is up-close, the further away from each camera the actor is, the trickier a high-resolution image can be, which is why volcap has, until now, typically only centered on one performer in a very small space. For Chen, a key challenge was adapting his system to Blomkamp's desire to go bigger.

"What Neill wanted to do, which was really crazy, was he wanted to scan maybe two people, three people, five people at once," Chen said. "So instead of needing this little one meter space, now we needed a five meter space, which means you need a crapload more cameras. And then all the cameras are so much further from the actor."

He continued, "There's a thing called inverse square law. It's like the further you are away from the source of information, it's not doubling the distance. It doesn't just make it twice as bad. It's actually exponential. Everything gets exponentially worse the further away you are. Because of that, we needed to use so many more cameras to capture this data that it ended up being 239 cameras, all recording 4K video at once. So I think, in the end of it, we captured 400 terabytes of data. So processing that was a challenge, to say the least."

Volumetric Camera Systems' work was eventually sent over to Universal Production Partners in the Czech Republic to create the final visual effects, tweaking the shots, playing with the lighting, and developing the eventual look of the film. When you watch Demonic, some shots might look like you're seeing a particularly gnarly video game glitch as Carly moves through the virtual space of her mother's mind, but according to Blomkamp, that's exactly the point.

"This is exactly why I wanted to use volumetric capture at some point in the movie, because the [low-budget] horror world is a place that would allow you to write the use of volcap into the script in a way where its glitches and errors would be accepted by the audience," Blomkamp said. "It's the only way that you could do it currently, because the technology isn't high resolution enough to narratively justify it within the story. So it's a prototype or it's glitchy or people don't really know what it is, and that's precisely what we did, and then once you've done that then you can kind of just let it be as sh***y as you want it to look, which is exactly my jam."

Though Demonic does spend plenty of its runtime in the real world, the final effect of the volcap process is an eerie journey into another landscape. Within the film's story, it works as an unsettling exercise in sci-fi horror. Within the larger filmmaking world outside of the story, it marks what Chen described as an unprecedented push forward in volcap creativity.

"It was intimidating because no one's ever done anything like this. And the difference between what we were doing, when we were [doing early volcap tests] with just a few dozen cameras versus going all the way to using 239 cameras... pretty much, as far as I know, this is the largest camera array that's ever been constructed in the world. There has never been anyone that's put 239 cameras, all recording into 4K together in one system."

Demonic is in theaters and on-demand on Aug. 20. Check back next week for more of our coverage of the film.

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Global DNA/RNA Extraction Kit Market 2021-2026: Extraction Kits for Cancer Patients for Diagnosis and Identification Forecast to Occupy a Significant…

Posted: at 12:54 am

DUBLIN, August 10, 2021--(BUSINESS WIRE)--The "DNA/RNA Extraction Kit Market - Growth, Trends, COVID-19 Impact, and Forecast (2021 - 2026)" report has been added to ResearchAndMarkets.com's offering.

The DNA/RNA extraction kit market is expected to register a CAGR of 7.26% during the forecast period of 2021-2026.

The COVID-19 pandemic impacted the DNA/RNA extraction kit market for the short time being due to restrictions on different business and research activities. Also, the diagnostics tests of other diseases and medical disorders in the hospitals and other clinical diagnostics establishments were affected due to a decrease in the turnout of the patients for tests because of COVID-19. But the high infection rate of COVID-19 and research activities by the key companies in the area of sequencing to expand their knowledge about the virus and its origin along with molecular diagnostics of the SARS-CoV-2 virus led to the development and launch of many DNA and RNA based COVID-19 kits, which proved to be very crucial and were in huge demand later. For instance, in April 2020, PHASE Scientific announced the commercial launch of the PHASIFY VIRAL RNA extraction kit for the detection of the COVID-19 virus, globally.

The major driving factor behind the growth of the DNA/RNA extraction kit market is the increasing investments in the research and development activities in different fields including molecular diagnostics for different chronic and infectious diseases. For example, according to the Organization for Economic Co-operation and Development, in 2018, the United States spent USD 552 billion on the research and development activities followed by China with USD 463 billion. The technological advancements, launch of new products by the key market players, and rising cases of cancer around the world will also complement the growth of the studied market. For instance, June 2020, Omega Bio-tek, Inc. announced the launch of an advanced viral RNA extraction kit for the COVID-19 testing, called Mag-Bind Viral RNA Xpress kit for the efficient extraction of the Viral RNA from nasopharyngeal (NP) swab samples.

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Other factors such as increased demand in the automation of DNA/RNA extraction technology, new user friendly and easy extraction kits, use of DNA/RNA in the profiling of new diseases causing microorganism will also boost the growth of the DNA/RNA extraction kit market during the forecast period. While the low awareness and availability of the kits and less market penetration in the underdeveloped and developing regions around the world are the major restraining factors for the growth of the DNA/RNA extraction kit market.

Extraction Kits for Cancer Patients for Diagnosis and Identification Will Occupy a Significant Share in the Market over the Forecast Period

In the body of a patient suffering from any kind of cancer, circulating cell-free DNA (ccfDNA) which originates from cancer cells are found in the bloodstream and thus are called circulating tumor DNA (ctDNA). A very sensitive RNA and DNA extraction kits are used to isolate and profile them and based on which treatment is performed on the patient. The companies are working towards it and developing and launching products related to the area. For instance, in May 2018, BioChain Institute Inc. launched a new cell-free DNA extraction kit called cfPure for the efficient isolation and detection of circulating cell-free DNA (ccfDNA).

According to the International Agency for Research on Cancer (IARC) data released in December 2020, about 1 in 5 people develops cancer in their lifetime, and 1 in 8 men and 1 in 11 women die from cancer, globally. As per its updated GLOBOCAN 2020 report, in 2020 there were about 19.3 million new cancer cases around the world and 10 million people died from it. So, the increasing prevalence of cancer will boost the growth of the DNA/RNA extraction kit market.

Key Topics Covered:

1 INTRODUCTION

1.1 Study Assumptions and Market Definition

1.2 Scope of the Study

2 RESEARCH METHODOLOGY

3 EXECUTIVE SUMMARY

4 MARKET DYNAMICS

5 MARKET SEGMENTATION

6 COMPETITIVE LANDSCAPE

Qiagen

ThermoFisher Scientific Inc.

F. Hoffmann-La Roche AG

Agilent Technologies

Bio-Rad Laboratories, Inc.

Promega Corporation

Danaher Corporation (Beckman Coulter Inc.)

Merck & Co. Inc.

PerkinElmer Inc.

bioMerieux SA

7 MARKET OPPORTUNITIES AND FUTURE TRENDS

For more information about this report visit https://www.researchandmarkets.com/r/71ytvk

About ResearchAndMarkets.com

ResearchAndMarkets.com is the world's leading source for international market research reports and market data. We provide you with the latest data on international and regional markets, key industries, the top companies, new products and the latest trends.

View source version on businesswire.com: https://www.businesswire.com/news/home/20210810005651/en/

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Global DNA/RNA Extraction Kit Market 2021-2026: Extraction Kits for Cancer Patients for Diagnosis and Identification Forecast to Occupy a Significant...

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U of T researcher uses VR to improve mental health of urban refugees, displaced youth – News@UofT

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Carmen Logieput on a virtual reality headset for the first time three years ago. Shewatched a short film about a Liberian womans experience in the Ebola epidemic.

It was a life-changing moment, says Logie, an associate professor in the University of TorontosFactor-Inwentash Faculty of Social Work. I felt like I was there with her. It was such a powerful way to develop empathy.

I immediately started thinking about how I could use this amazing technology in my work on health equity.

So, Logie began investigating VRhealth-care applications and quickly discovered a body of evidence from high-income countries demonstrating its mental health-care benefits, specifically in improving mood, reducing stress and teaching self-care.

But there was no evidence on how it could help in low-income countries or humanitarian contexts, Logie says.

Three years later, Logie is launching a study of a VR intervention focused on mental health in urban refugees and displaced youth.Working closely with youth and local community partners in Uganda, which hosts the third-largest number of refugees in the world, her team will develop a VR experience aimed at improving mental health literacy, reducing mental health stigmaand decreasing symptoms of depression.

Logies previous research found alarmingly high rates of depression among refugee and displaced young people living in five informal settlements commonly called slums in Kampala, Ugandas capital. Nearly three-quarters of young women and about half of young men aged 16 to 24 reported depression symptoms.

Now that weve measured this urgent problem, were focused on designing and measuring solutions, says Logie, who is Canada Research Chair in Global Health Equity and Social Justice with Marginalized Populations.

In addition to VR, the study will evaluate other mental health interventions delivered via text messages and web-based applications bothalone and in combination with VR. These will include psychological first aid, a World Health Organization approach that trains laypeople to provide practical support and care.

The VR content employed will be based on interviews with youth and community partners to understand the key factors that influence mental wellbeing, as well as strategies they find effective in managing stress. The plan is to co-develop a 30-minute VR session half of which will be devoted to a youth describing what its like to live with mental health challenges.

They might be walking through their community talking about their depression and how theyve felt stigmatized, says Logie. Then maybe theyll demonstrate some of the self-help approaches theyve learned and how they access formal mental health support.

Those watching the session through VR, meanwhile, will be immersed in the storytellers 3D environment.

The second half of the session will be interactive, allowing users to choose an avatar and practise coping strategies in virtual settings.Naimul Khan, director of the Ryerson University Multimedia Research Laband an expert on designing user-centred VR systems, is leading the VR design, development and implementation.

Mental health concerns disproportionately affect refugees and internally displaced individuals. And, despite the fact that 40 per cent of the more than 80 milliondisplaced people globally are under 18 years old, Logie says most studies on mental health interventions have focused on either young children or adults.

Theres a knowledge gap around what works with adolescent refugees that we want to help fill, she says. We also know very little about mental wellbeing among refugee youth living in urban areas, rather than formal refugee settlements, or camps.

Urban refugees tend to be overlooked because theyre more dispersed, adds Logie, even they confront unique pressures beyond the trauma of war and losing their homes. Unlike refugees in camps, where some food, sanitation and shelter is provided, urban refugees rarely have adequate access to the essentials.

Logie says it took some persistence to bring her VR idea to fruition. She initially acquired a headset and brought it to Uganda so her research collaborators could try it out. They had the same reaction as me: weve got to find a way to use it, she says. Butsecuring funding for a novel investigation of a relatively leading-edge technology wasnt easy. I was getting the message from grant application reviewers that VR was more suited to high-income countries, Logie says.

Logie acknowledges that its vital to adapt technology requirements to suit low-income contexts, but says the cost of VR headsets which can be sanitized and shared by community agencies continues to fall. Why shouldnt somebody in a refugee camp or slum access a digital tool that someone in Toronto is using to boost their mental health?

Grand Challenges Canada, an agency funded by the Canadian government and other partners, awarded the study $250,000 through their Global Mental Health Program the third project of Logies it has funded.

Logie says the research is ready to launch. The interview process will begin later this summer, VR development will take place through the falland the VR intervention will be implemented and evaluated in Kampala starting in the new year.

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Virtual reality game that reads body signals will ease pain for child cancer patients – MaltaToday

Posted: at 12:54 am

Researchers have developed a new game that combines artificial intelligence and virtual reality to help ease the pain for children undergoing medical treatments.

Virtual reality games could provide a new type of distraction therapy that may help young patients cope better with pain.

Developed by University of Malta researchers, the game illustrates an island populated by animals and allows players to engage and focus on the colourful and magical landscape.

Players physiological data is monitored in real time and artificial intelligence is used to detect heart rate and other body signals to infer a patients state and adjust the game accordingly. If AI notices that the player is not engaged enough, the game will introduce entertaining challenges.

The technology has been developed as part of the MORPHEUS project led by Prof. Alexiei Dingli and Luca Bondin from the Department of Artificial Intelligence at the University of Malta. The game has been developed in collaboration with Fabrizio Cali as lead designer, and supervised by Prof. Vince Briffa from the Faculty of Media and Knowledge Science.

MORPHEUS is a project of the University of Malta funded by Epic For Good Foundation.

The game will be rolled out for child cancer patients at the Sir Anthony Mamo Oncology Centre in Malta and at a later date available for the public.

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Virtual reality game that reads body signals will ease pain for child cancer patients - MaltaToday

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Jameis Winstons DNA is Etched in Stone with Unwavering Faith – Last Word on Pro Football

Posted: at 12:54 am

Just about everything is different this year for the 2021 New Orleans Saints after the prolonged era of Drew Brees. In a way, the acceptance is now on the doorstep going into training camp. Currently, the quarterback battles is ongoing, although the overwhelming favorite is no doubt Jameis Winston. Yet, nothing is certain in the NFL. One play can change the course of a career. One injury could impact the duration of playing time, versus holding a clipboard forever. But make no mistake, Winstons faith is all he needs.

The evolution of quarterback Jameis Winston is not exactly related to the football field. Oh it is important. The game of football has provided a life for him and his family beyond most players dreams.

At a recent practice, a reporter asked You sound like a pastor, is that the way youve always been? Perhaps Winston is not a bonafide pastor but his heightened insight into lifes lessons are relatable to many.

The walk of many Christians on and off the field is never a straight road. Winston has been upfront about his testimony. His unwavering dedication to God has changed over the years. Just like many of us.

However, many of us non-football players likely did not win a Heisman Trophy or a national championship. Also, being under a microscope can show the best and worse in people. And Jameis Winston is at peace with pleasing God before anyone else. The brokenness he has been through may be the one thing that works in his favor the most.

When Jameis Winston shared his testimony with Austin Carr recently, a whole new DNA was exposed the world. You have to be broken to rebound, was one of the best quotes Winston offered to Carr regarding adversity. If you look at all the figures in scripture, they had to be broken before they were blessed.

Evidently, there is a lot more to Winston than some of his successes and failures on the field. Many fans see players on the field act a certain way versus the real person off of the field. Some may not even care. Regardless, Jameis Winstons whole make up and faith is a part of his identity on and off the field present day.

In response to the question if he had always had the prose of a pastor, Winston responded, Ive always been optimistic, but sometimes I have been too optimistic, right, Winston said. I think I had to fine tune that just understanding reality. My gratitude was built from my father, from my mother. I had some humble beginnings and you talk about a pastor, like, I know my Lord and Savior got me.

Winston has matured over the years. Giving the reason for his successes come from somewhere bigger than him. In other words, Winston knows he cannot do it alone. And he laid it out profoundly to everyone to what moves him.

This makes him a better man and even a father or husband. Does this guarantee success on the field? Of course not. Even Tim Tebow could not promise divine intervention in between the hash marks. Still, doubt him and his beliefs then question Drew Brees. Brees often talked about his walk with Christ too.

There are other Christians whom too etch their game in faith: Russell Wilson, Patrick Mahomes, and former quarterback Phillip Rivers, to name a few. While this is true, a portion of those teams fans are not fanatical about players talking about their faith loudly.

Winston is his own man. He has his own walk. Whether that walk off the field will be a winner when all is said is done, only God knows.

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Seventy-four – The Express Tribune

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How does one even begin to express ones love for a homeland that is everything? Alpha and omega. Home, journey and destination. A sandbox where you make all mistakes and in a heartbeat, everything is forgiven and forgotten. Motherland and fatherland. And must one express this love? Or is it communicated and understood without saying anything like a sons is towards a parent. But then again this is the age of expression and children today remind you of their infinite love every five minutes. This is where the poverty of ones abilities holds ones tongue. I, for one, am no Tagore whose alchemy of words would create pure gold, or who had the company and help of titans like Yeats. I can only try to talk of the visceral nature of affection that powers my heart and preoccupies every waking hour of my modest existence.

Perhaps Tagores these words would come close to what I want to say: I am here to sing thee songs. In this hall of thine I have a corner seat. In thy world I have no work to do; my useless life can only break out in tunes without a purpose. When the hour strikes for thy silent worship at the dark temple of midnight, command me, my master, to stand before thee to sing. When in the morning air the golden harp is tuned, honour me, commanding my presence.

74 is an interesting number. Just one year shy of platinum jubilee. An age quite mature in human years but rather young in the comity of nations. One number further than 73, that Dr Sheldon Cooper of Big Bang Theory fame calls the best number. Why? 73 is the 21st prime number. Its mirror, 37, is the 12th and its mirror, 21, is the product of multiplying 7 and 3.... In binary 73 is a palindrome, 1001001, which backwards is 1001001. But it is neither 73, not 75. Almost there but not quite. Stuck between being and becoming. But let us not forget that it is the mirror of 47, the year of the countrys birth.

When you look at the nature of the 74 years of our collective cognitive experience, the first word that comes to mind is survivalism. Seriously. I have not seen another country that burns so much midnight oil mulling over existential threats, both real and imagined. This could be because of the spontaneous nature of Pakistans birth, the trauma left behind by the violence that accompanied freedom, Indias constant predictions about its failure, the fall of East Pakistan or a million more trials that it has gone through. While others sing of their countrys greatness, we pray for its long life. Humility is good, and prayers useful. But when you have lived long enough you do not need to revisit and re-litigate the causational factors of your countrys birth. It is there, we inherited it and it is the only place we have ever called home. Instead of justifying it every 10 minutes, we need to concern ourselves with the task of making it better. Dreams and visions matter here. Todays aspirations for tomorrow. And actions affirming those visions.

Reflecting on the independence day and journey so far proves to be a bittersweet experience for my generation. Sweet because it is the independence day. Bitter not because of the day or the country, but for who we (my generation) are. I call us the lost generation. Not the one that was led astray, but the kind that falls through the cracks when you are not looking. Heavy traffic on streets forces cars to switch to the slower lanes, where once boxed in, it may take hours to cover a journey of minutes. This is the story of my generations life. As Faiz put it, Kahaan se aaii nigaar-e-sabaa, kidhar ko gaii, abhii charaagh-e-sar-e-rah ko kuchh khabar hii nahin, (Whence came that darling of a morning breeze, whither has it gone? The lamp beside the road has still come no lessening.)

For a lifetime how many crises have we seen? The worst earthquake of the countrys history (2005), the worst floods (2010), the worst existential challenge since 1971 (the war on terror which left around eighty thousand dead including women and innocent children), perhaps the worst climate change challenge, economic hard times, belligerent neighbours and constant erosion of opportunities. The first Afghan war, refugee crisis, Afghan civil war, Taliban, the second Afghan war, now Taliban again. Modi, Doval and their defensive offence. Only God knows how many more upheavals we have to see before we meet our maker. And what leadership did we provide? All our national leaders are in their advanced sixties. My generation has never led the country. Perhaps the next generation will. We, my dear sirs, are truly a lost generation.

Then there is the matter of memory and introduction. The countrys memory is not what it once was. In the American romantic comedy 50 first dates, when Adam Sandler learns after falling for Drew Barrymore that she suffers from anterograde amnesia and he will have to re-introduce himself to her every single day, he does not baulk. But thats why stories are just stories. It is one tough job. And it must be a South Asian thing because recently an Indian poetess Rehna Sultana wrote: Ma, ami tumar kachchey aamar porisoi diti diti biakul oya dzai (Mother, Im so tired, tired of introducing myself to you.) I know it was said in a different context. But it fits this context too. Like a glove. Doesnt it?

So, you get it. Bittersweet. But here is the thing. This countrys most emancipating gift and one can die because of the intensity of love due to this, is that it is almost a blank slate. Too much can be written. And perhaps the best that has ever been written, anywhere. A paradise on earth, a city of love, a dreamers best dream come true. We owe it to our next generation to leave a better Pakistan than the one we inherited. No political pipe dreams or delusions of grandeur. Just a beautiful, peaceful, pluralistic place one feels proud to call home. From our eastern neighbour, we are getting too much hate these days. We have seen enough hate to last a lifetime. We will only deal in love and humanity now. As the prime minister so aptly put it, we will be partners in peace, not in war.

Great nations are built on the backs of many generations that die unrecognised. It seems my country needs only one. Perhaps, that is the only way for my lost generation to be found.

Happy 74th Independence Day everyone.

Published in The Express Tribune, August 14th, 2021.

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Altercation: The Ghost That Stalks the American Jewish Establishment – The American Prospect

Posted: at 12:53 am

This weeks Altercation is (mainly) authored by the extremely prolific Shaul Magid, professor of Jewish studies at Dartmouth College, Kogod senior research fellow at the Shalom Hartman Institute of North America, and rabbi of the Fire Island Synagogue in Seaview, New York. It draws on the research and arguments of his new book, Meir Kahane: The Public Life and Political Thought of an American Jewish Radical, though its contents are original to Altercation.

When people today hear the name Meir Kahane, most think about the militant and racist rabbi turned Israeli politician who founded a political party in Israel, was elected to the Knesset in 1984, and was removed in 1987 under the Racism Law legislated just for him, which made his party illegal. Many may be familiar with his policy to transfer Arabs out of Israel, his belief that Israel cant be both Jewish and democratic, and his critique of left-wing secular Israelis, calling them Hebrew speaking goyim.

Those more familiar with Israel may be aware of the ubiquitous Kahane was Right graffiti that dotted the landscape, especially after the second intifada in 2000, the emergence of a series of Israeli politicians who still view Kahane as a mentor, and the rise of small but vocal neo-Kahanist vigilante groups that terrorize Arab civilians in the name of Kahanes vision of what a Jewish state means. There are very few in Israel who are not familiar with the term Kahane or Kahanism and what that implies. His funeral in Israel in 1990 was one of the largest in the history of the country.

In contemporary America, however, things are very different. Kahane is almost a persona non grata in the American Jewish conversation, and when his name is mentioned, it is usually in regard to something in Israel. Ironically, Kahanes career began in America with the founding the Jewish Defense League in May 1968, and by early 1970 he had all but hijacked the Soviet Jewry movement through his call for civil disobedience and even violence to persuade Russia to free its Jewish dissidents. He testified before Congress about Soviet Jewry in June 1968. In March 1971, he organized a rally in D.C. for Soviet Jewry that was the largest rally ever held at the White House. He was the subject of long articles in Esquire and The New York Times Magazine, and was a feature interview in Playboy in 1972. JDL chapters sprang forth in many cities across the country, and his Soviet Jewry activism was the subject of a White House discussion between President Nixon and the Soviet ambassador. In 1971, a Look magazine poll showed that about 25 percent of American Jews had a positive view of the JDL. Kahane was not a marginal figure but a national one. It is likely that between 1968 and 1973 he was mentioned in The New York Times more often than any other rabbi in America.

So why do we know so little about Kahane in America? Jonathan Sarnas comprehensive book American Judaism does not mention him or the JDL at all. This is no oversight. There has been a marked attempt among scholars and institutional Judaism more generally to erase Kahane from American Jewish history.

Perhaps thats because Kahanes American record includes leading an organization that committed several murders. In 1985, regional offices of the American-Arab Anti-Discrimination Committee were bombed; the bombing in Santa Ana, California, killed ADC official Alex Odeh. Irv Rubin, the head of the Los Angeles branch of the JDL, publicly celebrated the killing, and eventually several JDL members were convicted of murders of other Arab Americans, while JDL members whom the FBI posted rewards for in Odehs killing remain free in Israel. Rubin died in prison awaiting trial for other violent acts. The JDL credo that set it apart from other far-right American Jewish organizations was its embrace of deadly violence.

Despite that, the ultranationalism of Kahanes worldview has seeped deep into the collective subconscious of American Jewry. We simply cannot tell the story of postwar American Jewry without Meir Kahane.

To get at what I am arguing, we must distinguish between two things: Kahanes tactics and Kahanes worldview. Kahanes tactics were very much a product of his time; the culture and race wars of the late 1960s, the radicalism of the New Left that led many young first-generation Jews to radicalize and adopt radical politics for Jewish causes after the New Left became anti-Israel after 1967. Kahanes militarism was a reflection of those years, even if his American followers proved to be a good deal more deadly than any wing of the New Left.

His worldview, however, was something different. It was an amalgam of Cold War anti-communism, an attack on American liberalism, and a systemic critique of the moderate nature of a mainstream Jewish establishment that was wary of making trouble. He challenged the regnant belief that liberalism and moderation would save the American Jewish dream. Interestingly, Kahanes early program was a diasporist one and not focused on Israel at all. An early JDL manifesto claimed the organization sought to save the American dream for Jews by instilling in its youth an assertive and activist program to fight assimilation, anti-Semitism, and intermarriage.

If we remove Kahanes militant tactics, his general worldview is alive and well.

His belief in the ubiquity of anti-Semitism in America was strongly resisted by the American Jewish establishment, and most American Jews. His belief that liberalism had no answer to intermarriage was similarly contested. He wrote a book on intermarriage in 1974, Why Be Jewish?, when few Jews were writing about intermarriage. Based on the 1972 sitcom Bridget Loves Bernie, he called American Judaism Bernism. He lamented the American bar mitzvah (all bar, no mitzvah) and offered a Judaism of the street before there was a social justice movement. When American Jews were still worried mostly about anti-Semitism on the right, he claimed anti-Semitism on the left was more threatening, and in the 1970s he argued that anti-Zionism and anti-Semitism were identical at a time when few made that connection. Kahane argued against Black nationalism the way some Jews today argue against critical race theory. In the late 1960s, he argued Jews were not responsible for whatever had happened to American Blacks, at a time when many liberal Jews favored reparations. Today, Kahanes view on reparations can be heard in many quarters of the moderate Jewish world.

On these and other issues, what Kahane was saying about American Jewry in the late 1960s and 1970s is what many mainstream Jews are saying in 2020. If we remove Kahanes militant tactics, his general worldview is alive and well. He founded Camp Jedel where Jews could learn to shoot guns as Jews. Today, some American Jews proudly send their children to the IDF military Gadna program, where American Jews learn to shoot guns as Jews. In some way, what Kahane wanted was to transfer Israeli survivalism to American shores. In the 1980s, Kahane argued that a Jewish and democratic state was schizophrenic. Today, faced with a half-century occupation, some Jews are questioning whether democracy should be sacrosanct if it challenges a Jewish state.

In short, if we separate tactics from worldview, Kahane has seeped into the collective subconscious of American Jewry more than we are willing to admit. In Israel, facing up to Kahanism is easier as it is more open and thus more a part of the conversation. The attempt to erase Kahanes legacy in America makes it much more difficult to recognize and confront. Many want to see him as a persona non grata. And therein lies the danger. The neoconservatism that emerged after Kahane was gone has been partly responsible for the rightward shift in some of American Jewry. But Kahanism lurks just beneath the surface. Someone once said that even though Kahane left America, America never left Kahane. I would add that in the collective mind of much of American Jewry, Kahane lives on in many of the moderate and genteel discussions about Jewish survival today.

I see that that Rabbi/Professor Magid is also a clawhammer banjo player and a student of Ken Perlman, one of the great living banjo virtuosos and musicologists of old-time banjo as well as the musical partner of Al Jabour who was, until his death a few years ago, the curator of American folk music at the Smithsonian in Washington D.C. There are a few people in this world who have too much talent to be accorded to a single person. Its just not fair. I had this thought twice in the past week, once when I was reading about Jhumpa Lahiri and again when I was reading about Viet Thanh Nguyen. Both are significant scholars as well as brilliant authors of fiction. (Of course, they are also terrific, albeit unnecessary, arguments for the value of an open immigration policy.) Ive not read Lahiris new novel, Whereabouts, originally written, infuriatingly to mere mortals, in Italian, a language she recently decided to learn, but I did read Nguyens magnificent two novels and can recommend them unreservedly. Start with The Sympathizer before moving on to The Committed.

We cant solve many of the worlds problems all by ourselves here at Altercation, but one I think we can dispose of is the sad fact that many people think Tom Jones is lame. Well, think again after you have watched Tom sing Long Time Gone with Crosby, Stills, Nash & Young; Raise Your Hand with Janis Joplin; Burning Down the House with the Cardigans; and, more recently, Leonard Cohens Tower of Song all by himself.

Finally, what the world needs now, no less than love sweet love, are conservatives who have a sense of honor and devote themselves to tell the truth, regardless of where it may lead. There are just a few of these left and we lost one with the passing of Yale historian (and Brooklyn College alumnus) Donald Kagan, whose four-volume history of the Peloponnesian War is one of the great scholarly achievements of the past half-century.

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After the last ‘summer of terrible drugs’ it’s time to make NZ’s temporary drug checking law permanent – The Conversation AU

Posted: at 12:53 am

With the summer music festival season approaching (COVID willing), hopes are high that the current temporary recreational drug checking law will become permanent. If and when that happens, New Zealand will take another small step down the long drug reform road from criminalisation to harm prevention.

Submissions to parliaments health select committee on the Drug and Substance Checking Bill have now closed, with a report due in October. If the stop-gap law rushed in for the 2020-21 summer is made permanent it will allow buyers of otherwise illegal drugs to have them independently checked without either the user or testing agency risking prosecution.

Its an important service, given the dangers inherent in the illicit drug market and the chances of substances being cut or compromised with other toxic stimulants, as happened with some MDMA circulating last year.

Making testing legal, even if what is being tested isnt, is a tacit acknowledgement that New Zealands war on drugs which began 122 years ago with the Opium Prohibition Act needs rethinking.

Despite generations of effort, the supply, demand and diversity of illegal drugs have grown, not diminished. Profit, pleasure and addiction have proved exceptionally powerful forces both internationally and domestically.

And while border seizures were way down due to COVID-19 restrictions, the black market in New Zealand for illegal drugs (not counting cannabis) is still worth an estimated NZ$77 million per quarter.

New Zealand first tried a different approach in 1987. The then Labour government introduced a national needle exchange program a world first that allowed intravenous drug users to receive clean needles. The program significantly reduced the risk of catching HIV or hepatitis C, saving lives and tens of millions in health spending.

The next innovation was a world-leading attempt to legalise and regulate the rapidly evolving synthetic drug market. It ultimately fell over due to practical problems implementing the Psychoactive Substances Act, public backlash and resistance to animal testing.

Read more: We can't eradicate drugs, but we can stop people dying from them

This pattern of innovation and failure has continued. While the use of medical cannabis became legal in 2019, the referendum on legalising recreational cannabis failed at last years general election.

A 2019 amendment to the Misuse of Drugs Act did pass, however, giving police clearer discretion not to prosecute for possession of small amounts of illegal drugs. Despite room for improvement, the new system has seen fewer prosecutions for personal use and has helped shift the focus towards health and away from the criminal courts.

Given Labours parliamentary majority and that the drug checking bill is a government initiative, its likely to pass. If for some reason it didnt, individuals or organisations handling drugs to check them would risk being charged with possession or supply.

Anyone allowing drug testing to operate on their premises would also be at risk because their co-operation could be seen as evidence of knowledge that illegal drugs were being consumed.

Most critically, if drug users cant get reliable information about what theyre taking, their uninformed choices carry unpredictable and potentially extreme risks. Nave customers and untrustworthy dealers can be a fatal combination.

Read more: Here's why doctors are backing pill testing at music festivals across Australia

Between 2017 and 2019, more than 70 deaths were attributed to synthetic cannabis in New Zealand.

When the volunteer drug checking and harm reduction organisation Know Your Stuff NZ checked 2,744 samples of other drugs at 27 events between April 2020 and March 2021, only 68% of all the samples checked were the substance that people expected. They called it the summer of terrible drugs.

Even cannabis sourced illegally for medicinal reasons is often not what people expect, or even effective. Not surprisingly, then, research has shown the vast majority of people would opt to have their illegal drugs tested if they could do so without risk of arrest and could trust the information.

Read more: If reducing harm to society is the goal, a cost-benefit analysis shows cannabis prohibition has failed

Its been argued that drug checking only encourages the use of illegal and harmful substances. But the evidencesuggests otherwise.

Rather, informed decisions produce changes in behaviour. When drug customers realise they have been misled or have misunderstood the nature of a given substance, they typically take less, or none.

The so-called war on drugs may be turning into a war on misinformation. If the Drug and Substance Checking Act finally comes into force by December, as has been promised, it will reflect a legislative trend toward harm reduction.

It will not stop the illegal use of drugs. But it will be one step further towards making New Zealand citizens safer from the scourge of unregulated and dangerous black markets for drugs.

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Why I Believe Celebrities Are a Key Piece in the Battle for Cannabis Legalization – Rolling Stone

Posted: at 12:53 am

Opinions expressed are solely those of the author and do not reflect the views of Rolling Stone editors or publishers.

Taxes, job creation, potential medical treatment for seizures and veterans with PTSD, ending the racist War on Drugs and mass incarceration from pot possession arrests, developing rational control over pot products these are all excellent and relevant reasons to support cannabis legalization, which more than 90% of Americans do.

The stigma is lifting. But, how? Why now?

Is it the result of the arduous and years-long work of legalization advocates and groups like NORML and the Marijuana Policy Project, along with the legal work of the ACLU?

Yes, but now theres another undercurrent of influence making itself felt: soft power.

Political scientist Joseph Nye coined the term soft power some 30 years ago. It refers to the ability to persuade others to do something without force or coercion. But where does soft power fit into cannabis policy reform?

While cheered by advocates, celebrity endorsements of cannabis legalization, in the beginning, were often undervalued or dismissed as frivolous. That is no longer the case despite the many who cares? I receive from cynical readers when I publish a celebrity interview. Many ask: Why is Martha Stewarts opinion important? What does Snoop Dogg really know? Why is DJ Khaled even talking about this? How are Elon Musk or Conan OBrien lighting up noteworthy events?

Although rhetorical, these questions deserve an answer. Celebrities who have crept out of the closet in support of cannabis legalization (and all that it implies) are no small deal. Its no secret that celebrities influence their millions of followers. A simple give CBD a try, I personally love it from the right icon could lead thousands of parents and grandparents to reevaluate their long-standing opinions.

Studies have analyzed the impact of celebrity endorsements and declarations on public opinion, foreign policy, health-related issues, and consumption habits. And one thing is clear: They matter. A recent poll showed that roughly 36 percent of Gen Zers, 32 percent of Millennials, 24 percent of Gen Xers and, 19 percent of Baby Boomers admitted that, celebrity opinions on political and social issues are effective in influencing their midterm vote.

And now, it seems, cannabis could be getting a boost for the same reason.

The Rolling Stone Culture Council is an invitation-only community for Influencers, Innovators and Creatives. Do I qualify?

Jane Fonda never failed to move the needle when she got behind a cause. Whether it was to stop a war or demand civil, Native American, LGBTQIA+, and abortion rights, or decry global warming, Jane was never irrelevant.

In a recent interview I conducted with Jane Fonda for Forbes, Fonda touched on cannabis, its role as her new sleep aid and the need for its re-legalization. As the media picked up the story and news of Fondas new sleep aid traveled far and wide, dozens of readers emailed me to share their change-of-heart stories, having been influenced by Fondas dignified honesty. Indeed, an increasing number of the countrys largest demographic, Baby Boomers, are turning to cannabis.

And this was not the first time celebrities have backed cannabis.

DJ Khaled, the well-known musician and entrepreneur, recently launched a CBD brand, citing a personal wellness journey as the inspiration. Carlos Santana launched a cannabis brandthat honors his heritage, citing his belief that there is a nuanced difference between medicine and drugs, and that cannabis falls under the former.

When Snoop Dogg connected cannabis consumption and plant-based eating, his young fans took a hard look at their nutrition habits. Martha Stewart has openly discussed her CBD use and her inspiration for launching her own cannabis brand, which incidentally was her long-time friend Snoop Dogg. When Nicole Kidman endorsed a cannabis brand, people took notice given her considerable acting career, meaning her message has reached many people across America.

When Magic Johnsonand Megan Rapinoe came out in defense of cannabis-derived products for athletic recovery, their health-conscious followers likely reacted accordingly.

And the list goes on, and on, and on.

Some sports legends have pushed for changing cannabis policy in their professional leagues too.

Super Bowl champion Marvin Washington has repeatedly argued for making NFL policy more cannabis-friendly. He is currently involved in a lawsuit challenging the federal governments stance on cannabis and its continued Schedule I status as a controlled substance.

An athletes influence over cannabis policy can also occur unintentionally. We saw this with the disqualification of record-breaking sprinter ShaCarri Richardson from the Tokyo Olympics after she was found to have cannabis in her system, albeit while in a marijuana-legal state when she was not competing. Support for the fastest woman in the world was widespread and swift. The debate gripped the country, from the White House, anti-doping agencies, Congress, and the media.

Meanwhile, amid all the noise, cannabis pushed further into the accepted column of American society. After all,one of the worlds richest menandformer host of the Tonight Show both smoked a joint on live TV.

The stigma of weed is lifting, which begs a question: Are celebrities leading the way? Perhaps. Either way, more power to them.

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