Monthly Archives: October 2019

Revive Fashion Show combats human trafficking, fast-fashion – UW Badger Herald

Posted: October 16, 2019 at 5:10 pm

The verb revive means to restore to life or consciousness or to regain life or strength. The first-ever Revive Fashion Show on Oct. 6 did exactly that.

Hosted and sponsored by Fair Indigo, an ethical and sustainable clothing company based in Madison, all of the proceeds from the show benefit the Dressember Foundation.

Dressember, a non-profit organization founded by Blythe Hill, provides education, life skills, training, medical treatment and aftercare to the survivors of human trafficking. Hill initially started to hear about human trafficking in 2005 when she learned that slavery continues to exist in every city in the world, including all fifty states.

UW professor applies research on sex, human trafficking to help local victimsThe University of Wisconsin Campus Womens Center hosted UW gender and womens studies professor Araceli Alonso Thursday to discuss her Read

According to the foundation, approximately 35 million people are currently confined to slavery, 70% of them being women. This is becoming the worlds fastest-growing criminal industry and its flourishing. Because of what we know as fast fashion in the clothing industry, society is purchasing 400% more clothing today than we did 20 years ago.

Not only this, but the workers making these clothes earn just 1-3% of the retail price of an item. Statistics such as these are what inspired the Revive fashion show to come to fruition.

We at Fair Indigo really realized how Dressember and Fair Indigo have been combating this issue separately and in different ways for years, Stacy Imhoff, a co-organizer for the Revive Fashion Show, said. We thought it was a great opportunity to get our two like-minded organizations together to bring more awareness to the issue of ethical and fair trade fashion.

As a graduate of the University of Wisconsins textile and apparel design program, Imhoff approached other women who had also graduated from the program in addition to harmonious brands and businesses within the community. The event had a mix of different brands, vendors and models participating, all of which were proponents of ethical fashion.

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At this family-friendly event, vendors were eager to educate the public about the benefits of this cause.

A pop-up market before the show featured handmade ethical goods from makers and brands around the area, where a portion of the proceeds would go towards the Dressember Foundation.

Here, guests of the event were immediately engrossed in an environment full of passion and enthusiasm to inform individuals about the cornerstone of Fair Indigo and Dressember: ethical fashion.

Ethical fashion the exact opposite of slave labor that is employed to make cheap fast-fashion clothing is what Fair Indigo is all about, Imhoff said. We pay the people who make our clothes a fair, living wage and ensure they have clean and safe working conditions and are treated with respect.

These brands intend to stray away from the expectation of inexpensive and disposable clothing, which causes a high demand for cheap labor.

[Cheaply made clothing] also results in more waste more clothes are thrown away or donated to second-hand shops that are then exported to other countries for resale or disposal. If we can find a way to reuse what we already have, there is less demand for cheap labor. Plus its just generally better for our environment too, Imhoff said.

One stand at the market was home to Lev Apparel company where founder Krystle Marks said she employs women from New Delhi, India at a fair living wage to make clothing. This pulls the women out of poverty while empowering them to contribute to a product with a purpose.

Lack of women in entrepreneurship hurts businesses, start-ups, panel of female entrepreneurs sayLocal female entrepreneurs shared their experience and expertise in a panel Thursday night. The panel, hosted by University of Wisconsin Read

Following the pop-up market, guests gathered around the runway to witness models dressed in unique, fashion-forward, recycled garments. Models wore pieces made of everything ranging from neckties to mens collared shirts to old tablecloths.

Fabric that was otherwise deemed unwearable was converted into hand-painted art. The oohs and ahs were audible as each piece was presented and smiles lit up the room.

We at Fair Indigo see this as a community-building event to bring like-minded organizations and people together around a common goal, Imhoff said in response to her hopes for the fundraiser. Its been a really fun event to organize and see how excited people are to participate.

What started as a style challenge for a college student in need of a creative outlet ultimately became a global campaign stretching across over 115,000 supporters, 45 countries and six continents and continues to grow. As the Dressember Foundation website says, Dressember is more than a dress.

Join thousands of advocates around the world by wearing a dress or tie every day this December as a symbol of liberty and empowerment to declare inherent dignity for all people, a line from one of the videos played during the fashion show.

According to a video from Dressember at the fashion show, For one month, with a dress as our flag, we will carve a path to a better future for women everywhere.

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Deliveroo riders boycott Wagamama amid pay concerns – The Tab

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Theres a very good reason you couldnt get your Katsu curry last week

Last week, around 80 Deliveroo riders refused to take orders from Wagamama on the Triangle and at Cabot, amid concerns about pay.

According to the organiser of the strike, Joseph Nunes, 43, riders can wait up to 25 minutes in a Wagamama restaurant while they prepare the food.

The wasted (and unpaid) time means that riders can do significantly fewer trips.

We all dread the waiting time at Wagamama. Its not fair on the riders. Nunes told The Bristol Post.

While the minimum wage for an over-25 is 8.21, Nunes claims to make 6 per hour when you factor in petrol costs, moped maintenance and insurance. He described his working conditions as similar to slavery.

The strike occurred on Tuesday, Wednesday and Thursday of last week, following a 100-strong strike concerning pay that occurred on 21st of September.

A spokesperson for Deliveroo said: Deliveroo works closely with our restaurant partners and the riders we work with to make sure we have an efficient and reliable service.

Deliveroo has recently made changes to rider fees so riders are paid more for longer distance deliveries and wait times at restaurants are taken into consideration when calculating how much riders are paid.

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After a year in Kennett Square, this business gets a ‘Clean Slate’ – southern chester county weeklies

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KENNETT SQUAREEvery product has a maker, and every maker has a story, says Clean Slate Goods owner Kari Matthews.

Shes passionate about carrying beautiful, handmade goods that her customers will love and that also create jobs for artisans in vulnerable circumstances. As shes learned more about communities of designers and makers around the world, shes heard many stories and been inspired by the amazing transformation that happens when people have dignified work and earn a fair, livable wage.

Clean Slate Goods opened last year, tucked into its cozy spot around the corner from State Street on North Union.

I was happy and comfortable there, Kari says, and the last thing on my mind was a move. But when the landlord mentioned that the larger, centrally located location where the landmark State and Union had been was becoming available, she said, Im not interestedtell me about the space. She smiles. But the doors continued to open, and although I couldnt quite imagine another renovation so soon after the last one, it became clear that Id regret it if I didnt take the opportunity.

After a chaotic month of renovation and a nail-biting, down-to-the-wire photo finish, she opened on August 1st. She couldnt have done it without help from her husband, staff, small group Bible study members, friends in the Kennett community, and my mom, who was here every day, she says. Now the bright, beautifully renovated shop is the newest addition to State Streets vibrant shopping scene.

Kari has refined her vision for Clean Slate Goods over the past year. Im a little more maker-focused, she says. I make sure that every brand I carry is helping artisans who lack opportunity for dignified jobs. Staying true to such a mission entails challenges.

There are so many for-good brands, she says. Personally, I want to help every good cause out therefrom planting trees and cleaning up the oceans to supporting local artisans. But she knows if she tries to save everyone she wont help anyone. Its cool how God puts different passions on different peoples hearts so we as individuals dont have to do it all, she says. Instead, we work together as a community.

Kari lives in West Chester with her husband Jason, who describes himself as a soccer dad, and their three sons. The shop, she says with a smile, gives her girl time. Shes found a caring community here in Kennett Square and the perfect home for Clean Slate Goods. Kennett Square is beyond cool, she says.

Part of what fuels Karis passion for the artisans whose work she carries is her own experience as a maker. I know what goes into creating handmade goods, she says, and I also know how difficult and important it is to find the right marketplace for them.

Clean Slate Goods began in 2014 as Clean Slate Designs, as Kari created home dcor pieces from reclaimed wood and sold her products at local vendor shows. As her knowledge of, and appreciation for, handmade goods grew, she also began to learn more about companies around the world that were training individuals in marginalized communities and providing them with sustainable employment.

She partnered with some of these companies to sell their goods alongside her own work at shows and on her website. Her growing desire to be able to do good and make a lasting difference for these artisans developed into Clean Slate Goods.

The cohesive aesthetic of the store is also critical. Pity sales only go so far, Kari says. In order for this market to be sustainable for the makers, they have to create goods that are high quality and that people want to buy. Often designers work with artisans to help them create product lines that are on trend.

These two piecescreating jobs that pay fair wages as well as a high design aesthetic and qualityare my equation for accepting a brand, Kari says. Customers often come to Clean Slate to find the perfect, one-of-kind giftsomething they know the recipient will actually love.

She carries such a great variety of unique products at affordable price points that people can find a great gift, with a story behind it, for anyone on their list. Its almost a two-for-one gift, she says, because buying a handmade product truly impacts the life of the person who made it.

Supporting these artisans is a step beyond charity. When people in vulnerable communities receive a fair wage, theyre able to bring themselves and their families out of crushing circumstances including poverty, addiction, incarceration, and prostitution. The point is not to make us feel good about ourselves because were helping the poor; the point is to be conscious of the makers behind the products we buy and give them the diginity they deserve, Kari says. Talent is evenly distributedopportunity is not.

She enjoys highlighting the makers behind the products and sharing their amazing stories. And, she says, as we buy their products we can be part of their stories too. One of the new brands shes carrying, Haiti Design Co., employs over 150 people and also helps to provide resources including healthcare and artisan entrepreneur training and mentorship so people can start their own businesses.

Their products, including leather goods and beaded earrings, marry design with purpose. We can tend to be more reactive in the aid we give to vulnerable communities, Kari says, but staying in a place and figuring out how to help create sustainability in that context is hard work. There are many different and inspiring models for creating this sustainability. Instead of operating their own factories, for example, ABLE supports people in Ethiopia who already have factories by working with them. Causegear is yet another brand for good, and purchasing one of their beautiful and fashionable bags helps support and free women in South Asia from slavery and poverty.

Bags are our bread and butter, Kari says, and currently Clean Slate carries ten different brands of one-of-a-kind bags. She also carries a wide range of jewelry as well as soap, candles, beauty products, home accessories, toys, and more. In her new, expanded space shes looking forward to adding a few key staple pieces of clothing made by artisans. A selection of fun and heartfelt handmade cards for every occasion makes Clean Slate Goods a one-stop-shop for gift giving.

Kari also wants Clean Slate Goods to be a place where people from the community can gather and be creative together, and she hopes to offer a creative workshop every month. After her Oct. 3 chocolate tasting with Estelle Tracy, plans are in the works for succulent and Christmas ornament workshops. Sign up for the Clean Slate Goods newsletter at CleanSlateGoods.com and follow her @cleanslategoods

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Keep me in your heart: Race and class politics in the Trump era – People’s World

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People in the audience hold up signs as President Donald Trump speaks at the Pennsylvania Farm Show Complex in Harrisburg, Pa., April, 29, 2017. Some academics are beginning to seriously study the fascination some white Americans have with "Trump's fascist rhetoric," and how, in the face of intensifying exploitation, they are looking to Trump "the boss" to save them. | Carolyn Kaster / AP

Idiomatic expressions by their nature are difficult to pin down. They point to intended meaning but depend mostly on the hearer or reader to construct a definition from context. But meanings arent arbitrary, and they depend on the contested and conflicted sociality of language.

This linguistic dynamic holds for the expression heart of America. That idiom is in the subtitle of a new book by sociologist Jennifer M. Silva, titled, Were Still Here: Pain and Politics in the Heart of America. The books goal is to explain the puzzle of working-class politics, or why the working-class, in part, seems to support the authoritarian philosophy of the Trump administration.

Consider: The heart of America implies something definable and knowable about the two objects presented in the phrase. America seems obvious. It refers to a place, a country, usually by the political name of the United States of America.

But, many critical voices challenge this conflation of America with the U.S., pointing instead to its contested history, replete with genocide, slavery, brutal war, class exploitation, and imperialism. What Mexican-American author Jos Ordua calls, in his book The Weight of Shadows, our foundational violence. Foundational in the sense that it is continuously the starting point, repeatedly, for constructing Americanness in a particular way.

The U.S. Constitution supposedly created a democratic, representative, and liberal set of freedoms. The framers, however, crafted many of its provisions to defend slavery and genocide, as historian Gerald Horne writes in his books The Counterrevolution of 1776 and The Apocalypse of Settler Colonialism. These atrocities had become imperatives for capitalist development and territorial expansion.

While some people usually regard the political system as a democratic one, it is also accurately characterized as corrupt and dominated by the 1%. (Although saying that can earn one the label of being unpatriotic). Americas economic system is called a free market. But it is defined by worker exploitation, oligarchy, environmental waste, racist and gendered income and wealth inequalities, and corrupt, inefficient corporations that control most political processes.

America furthermore means more than the United States. A name derived from its colonialist history, America may refer to the entire Western Hemisphere and its peoples. The narrowest usage of the term America typically betrays willful indifference to the existence, histories, and cultures of most inhabitants of the Western Hemisphere, including the descendants of the indigenous, enslaved people, and migrants. The political and economic interests of corporations whose power emanates from the U.S. and the comprador classes govern many Western Hemispheric countries.

At bottom, America is a place saturated with contradiction. A never-perfected (dis)union of geographies, cultures, peoples, and social classes; lands of white colonial settlement, white supremacy, and cultural oppression. A site, too, of anti-colonial struggle, anti-racist insurgency, and revolutionary consciousness.

So, what does it mean to be at the heart of this place?

A quick look at an online list of 70 American-English idiomatic expressions that use the word heart reveals that it tends to mean something like a site of ones authenticity, honesty, integrity, love, emotion, fervency, compassion, courage, romantic love, ones feelings. Spatially, we use it to mean a center or fountainhead of passion, meaning, values, and essential humanity.

When we get to the heart of the matter, we speak of a place of origin, authentic meaning, the truth about a situation. When something is in our heart, we mean that it has a deep, compelling value and worth in the meaning of our lives. When we talk about a heartland, we likely mean the place of the original identity, the place where you can find those who are the original people of that culture. When we heart something, we mean that we love it, identify our interests, goals, culture, and sense of worth with that thing. When something is felt deep in my heart, it means that truth beyond the surface is felt rather than rationally known. The heart is an instrument more powerful than logic in discerning truth.

Silvas phrase in the heart of America, then, locates her research findings in the space of a merged emotional center, original identity and authenticity, and fundamental truths about America. Because America is more than the geography of the U.S., I argue that meaning is implicit in her words, even if she doesnt intend it.

The full subtitle is Pain and Politics in the Heart of America. Pain in ones heart references a deep wounding, possibly life-threatening, but perhaps of such emotional effect as to render permanent the disruption of bonds of friendship, love, or even kinship. I will return to the political dimension indicated in the subtitle shortly.

The main title, Were Still Here, an utterance from a working-class person, stakes a rhetorical claim to endurance and resilience, despite the pain experienced at the heart of America.

In her opening chapter, Silva describes her methodology for this study as a fluid one. She had intended to study white working-class views of Donald Trump in the campaign season before the 2016 election. She focused her research on a community in the Southern portion of Pennsylvania, which she labels Coal Brook, to hide the identities of her interviewees. She claims, however, that she struggled finding people who felt strongly enough about politics to fully identify with a political party or advocate for specific policy platforms. So, her research agenda shifted.

Evidently, reality forced her to reconsider the media and political stereotype that equates the working class with white people or the equally distorted distinction between the working class and low-wage workers. In this vein, Carmen Rojas, the founder of The Workers Lab, has argued, The caricature is a blue-jeans wearing, Harley Davidson riding, white man who has a job his dad and granddad once had. This working man, as hes often portrayed in the media coverage he gets, feels left behind, misunderstood, and angry because he cant go anywhere without hearing a language other than English and cant turn on the TV without Black and Latinx faces overwhelming his options. The frequent association of the white working class exclusively with small towns and rural communities adds a further distortion of reality.

As it turns out, none of Silvas interviewees were coal miners. And, while the surrounding area once employed 175,000 coal miners, since the 1970s, it has become a collection of abandoned mines with only a handful of workers still associated with that industry. Further, as she notes, in the past decade, rising housing costs, poverty, and crime have pushed black and Latino people out of urban economies and into the coal region.

Instead of finding some realistic correspondence to the white male miner stereotype, Silva spoke with people who hold a variety of jobs, educational statuses, income brackets, genders, ethnic and racial identities, political beliefs, and relationships to the concept of the heart of America. Many white people, who had made this place like Alabama without the blacks, felt threatened by the demographic changes. Change threatened their claim on white racial exceptionalism and identity as the working class in the heart of America.

This threat produced an emotional response articulated as loss and being left behind. It fueled resonance with Trumps racially coded slogans and demands such as Make America Great Again, a wall on the U.S.-Mexico border, and restrictions on migration from non-white and majority Islamic countries. Trumps rhetoric seemed to align with prior equations of crime and disorder with people of color encoded in the assertion that Blue Lives Matter. This transitional period represented a new landscape in Southern Pennsylvania politics, which had just a few years back tended to support Democratic candidates actively.

Economic change does lie at the heart of these big political shifts to the authoritarianism and racism of the Trump campaign. Larger numbers of non-white, working-class people in their midst, however, served most to disrupt white self-identifications with the media stereotype. Indeed, Silvas evidence reveals that many whites had (perhaps reluctantly) accepted the exchange of economic insecurity for the psychological comfort of white racial exceptionalism. White emotional affiliations with a caricature of the hard-working white person recall W.E.B. Du Boiss concept of a psychological wage of whiteness.

Class politics in a multi-racial society, by their nature and by all rational logic, require a political and cultural identification with other people from racial and ethnic communities based on the work they do and their relation to the boss and to capital. As Silva writes, borrowing from the Marxist cultural historian E.P. Thompson, social class as a political identity, is neither automatic nor something to be assumed in advance. Rather than a response to sharing the same education level, income bracket, or job, it is a process of constructing, contesting, and remaking a collective identity through concrete social relationships that generate values, traditions, and shared interests.

In other words, organized action, community building, and struggle produce a politicized class identity.

She writes that the new political terrain represented by support for Trump indicates that class is not happening as it used to. This is an insightful remark. It links a shift in class politics to the emergence of a significant fracture in class identity and action in the region that is new, perhaps within the last decade. It suggests attempting to associate this fracture solely with structural changes, such as the decline of coal, manufacturing, unionization rates, or of the emergence of neoliberalism, would be flawed and partial.

What it indicates rather is something potentially more disturbing. If the process of class identity formation has shifted in the past decade, it suggests that class had been made and remade in ways that seemed to uphold racial/gendered pieces of the working-class caricature. Indeed, that this caricature was identified with Democratic Party politics in Southern Pennsylvania suggests a disastrous association of white males as icons of Democratic Party working-class politics up to the Trump era. Silva shows that this iconic association made voting for Hillary Clinton far too hard.

Any way you skin this cat, the evidence shows that many people, in the worst traditions of Americas foundational violence, had constructed a working-class identity that rested primarily on their whiteness. Instead of a democratic alliance of all people aiming to claim power over their lives and communities in the face of corporate dominance, environmental disaster, and rampant economic exploitation, many whites seem to want tight control over the advantages of being a white person. The seeming loss of these feels like the worst disaster, the beginning of the decline of our country.

As a result of apparent trends such as this, researchers have begun to talk about white Americans fascination with Trumps fascist rhetoric, as political scientist William E. Connolly argued in a recent study of similarities between Trumps and Hitlers leadership styles. Philosopher Samir Gandesha pointed to an increase in popular identification with the aggressor among white Americans as a component of the authoritarian personality now apparently more visible in American society. Anthropologist Gregory Duff Morton linked popular acceptance of Trump as the boss to emergent structural changes in the economy that have intensified exploitation for workers.

Since altered racial demographics have challenged the caricature of white working-class identity, a rupture in political identities occurred. This crisis shows that the decline in unionization, especially one focused on organizing a multi-racial alliance, has left the ground open for such a disastrous turn of events. It also shows that racism wont let us put into our heart of hearts the people who should mean the most to us: those who share our struggles, our workspaces, our aspirations for a fully democratic and equal society, our love for hard work as a source of meaning for our lives, our belief that we, together, all of us, make the world every day through our joint labor and deserve to control its future.

Were Still Here: Pain and Politics in the Heart of America

Jennifer M. Silva

Oxford University Press, 2019, 224pp., $24.95

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Research links UK supermarkets to abuse of farm and plantation workers – Retail Insight Network

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Some farms and plantations that supply UK supermarket giants are being linked to poor pay and harsh working conditions, according to new research by charity Oxfams global Behind the Barcodes campaign.

The research found that workers in India, Brazil and five other countries are being exploited during the production of tea or fruit for import to retailers including Lidl, Aldi, Sainsburys, Tesco and Morrisons.

Interviews with workers across 50 tea plantations in Assam found that a lack of access to toilets and safe drinking water spreads typhoid and cholera among workers. Wages are also low, with women workers being the lowest paid when doing labour-intensive jobs, causing them to be on ration cards from the government.

The supermarkets confirmed they source their own brand tea from the companies visited in Oxfams research, with Lidl confirming they source their tea from the Assam region. The supermarkets also take the largest share of the price of the tea bought by consumers, with workers collectively receiving 3p of the 79p pence paid by consumers.

Oxfam ethical trade manager Rachel Wilshaw said: Despite some pockets of good practice, supermarkets relentless pursuit of profits continues to fuel poverty and human rights abuses in their supply chains. Supermarkets must do more to end exploitation, pay all their workers a living wage, ensure women get a fair deal and be more transparent about where they source their products.

Supermarkets are snapping up the lions share of the price we pay at the till but the workers who toil for hours to harvest tea and fruit face inhumane working conditions and are paid so little they cant even feed their families.

Dun & Bradstreet head of product and strategy Chris Laws said: With more than 40 million people living in some form of modern slavery in the world today, this problem requires a global situation which has NGOs, governments and businesses working together. Oxfams research has shone a spotlight on how this problem allegedly extends to some of the biggest retailers in the UK through their supply chains and the call for more supply chain transparency to identify and address risks has never been louder.

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Applied Therapeutics to Present Data Highlighting AT-007 for the Treatment of Galactosemia at the American Society of Human Genetics (ASHG) 2019…

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NEW YORK, Oct. 16, 2019 (GLOBE NEWSWIRE) -- Applied Therapeutics Inc. (Nasdaq:APLT), a clinical-stage biopharmaceutical company developing a pipeline of novel drug candidates against validated molecular targets in indications of high unmet medical need, today announced the Company will give an oral presentation of data at the American Society of Human Genetics (ASHG) 2019 Annual Meeting in Houston (October 15-19) on AT-007, a central nervous system (CNS) penetrant Aldose Reductase inhibitor (ARI) in Phase 1/2 development for treatment of Galactosemia. In addition, the Company will host an ASHG Educational Symposium featuring a panel of Galactosemia experts.

Details on the Oral Presentation and Educational Symposium are below:

Oral Presentation

Title: AT-007, a Novel CNS Penetrant Aldose Reductase Inhibitor Prevents the Metabolic and Tissue Specific Abnormalities of Galactosemia, in a GALT Deficient Rat Model of DiseaseDate and Time: Saturday, October 19, 2019, 8:30-8:45am CTPresenter: Riccardo Perfetti, MD, PhD, Chief Medical Officer of Applied TherapeuticsSession: 99Location: Room 370A Level 3/Convention Center

The presentation will be available on the ASHG conference website as well as the Applied Therapeutics website following the session.

Galactosemia Educational Symposium

Title: Development of an Oral Treatment for GalactosemiaDate and Time: Thursday, October 17, 2019, 12:45-2:00pm CTLocation: Marriott Marquis Houston, Room Briargrove AB, Level 3Key Topics:

Additional details for the event can be found here.

About Galactosemia Galactosemia is a rare metabolic disease that affects how the body processes a simple sugar called galactose, and for which there is no known cure or approved treatment available. Galactose is found in foods, but the human body also naturally produces galactose on its own, so dietary restriction cant prevent complications of disease. It is estimated that the U.S. Galactosemia population is approximately 2,800 patients, based on newborn screening data identifying 2,500 infants through 2014, and the estimated birth rate of 80 patients per year. High levels of galactose circulating in the blood and tissues of Galactosemia patients enables Aldose Reductase to convert galactose to a toxic metabolite, called galactitol, which causes long-term complications ranging from CNS dysfunction to cataracts.

About AT-007AT-007 is a central nervous system (CNS) penetrant Aldose Reductase inhibitor (ARI) in Phase 1/2 development for treatment of Galactosemia. AT-007 has been studied in in an animal model of Galactosemia, which demonstrated that AT-007 reduces toxic galactitol levels and prevents disease complications.Applied Therapeuticsis conducting a biomarker based development program in patients with Galactosemia, based on the recently released draft industry guidance on drug development for low prevalence, slowly progressing rare metabolic diseases. The company received Orphan Designation for AT-007 for Galactosemia inMay 2019.

About Applied TherapeuticsApplied Therapeuticsis a clinical-stage biopharmaceutical company developing a pipeline of novel drug candidates against validated molecular targets in indications of high unmet medical need. The companys lead drug candidate, AT-001, is a novel aldose reductase inhibitor (ARI) that is being developed for the treatment of Diabetic Cardiomyopathy, or DbCM, a fatal fibrosis of the heart. The company initiated a Phase 3 registrational study in DbCM inSeptember 2019.Applied Therapeuticsis also developing AT-007, a central nervous system penetrant ARI, for the treatment of Galactosemia, a rare pediatric metabolic disease, and initiated a Phase 1/2 clinical trial inJune 2019. The preclinical pipeline also includes AT-003, an ARI designed to cross through the back of the eye when dosed orally, for the treatment of diabetic retinopathy, expected to advance into a Phase 1 study in 2020.

Forward-looking StatementsThis press release contains forward-looking statements that involve substantial risks and uncertainties for purposes of the safe harbor provided by the Private Securities Litigation Reform Act of 1995. Any statements, other than statements of historical fact, included in this press release regarding strategy, future operations, prospects, plans and objectives of management, including words such as "may," "will," "expect," "anticipate," "plan," "intend," and similar expressions (as well as other words or expressions referencing future events, conditions or circumstances) are forward-looking statements. These include, without limitation, statements regarding(i) the design, scope and results of our clinical trials, (ii) the timing of the initiation and completion of our clinical trials, (iii) the likelihood that data from our clinical trials will support future development of our product candidates, (iv) the likelihood of obtaining regulatory approval of our product candidates and qualifying for any special designations, such as orphan drug designation, (v) our cash runway and the timing of our clinical development plan.Forward-looking statements in this release involve substantial risks and uncertainties that could cause actual results to differ materially from those expressed or implied by the forward-looking statements, and we, therefore cannot assure you that our plans, intentions, expectations or strategies will be attained or achieved. Such risks and uncertainties include, without limitation, the uncertainties inherent in the initiation, execution and completion of clinical trials, in the timing of availability of trial data, in the results of the clinical trials, in the actions of regulatory agencies, in the commercialization and acceptance of new therapies. Factors that may cause actual results to differ from those expressed or implied in the forward-looking statements in this press release are discussed in our filings with theU.S. Securities and Exchange Commission, including the Risk Factors contained therein. Except as otherwise required by law, we disclaim any intention or obligation to update or revise any forward-looking statements, which speak only as of the date they were made, whether as a result of new information, future events or circumstances or otherwise.

Contacts

Investors:Maeve Conneighton(212) 600-1902 orappliedtherapeutics@argotpartners.com

Media:Brittany Horowitz(212) 704-4466 ormedia@appliedtherapeutics.com

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Applied Therapeutics to Present Data Highlighting AT-007 for the Treatment of Galactosemia at the American Society of Human Genetics (ASHG) 2019...

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New Data from Ambry Genetics Demonstrates Impact of First Major Advancement in Over 10 Years to Increase Diagnostic Yield in Genetic Testing for…

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ALISO VIEJO, Calif., Oct. 15, 2019 /PRNewswire/ --Ambry Genetics(Ambry), a leading clinical genetic testing lab, will present data at the American Society of Human Genetics (ASHG) annual conference this week from the first prospective study of paired RNA and DNA genetic testing for hereditary cancer risk, called +RNAinsight. The data from this study of the first 1,000 patients to receive +RNAinsight show a significant increase in diagnostic yield (identifying mutations in our DNA as disease-causing) compared to DNA testing alone. This is the first major increase in diagnostic yield for hereditary cancer risk in over 10 years. Through +RNAinsight, Ambry is the first and only lab to offer paired RNA and DNA genetic testing for hereditary cancer as a commercially available clinical test.

Standard DNA testing excludes large portions of DNA, thereby missing some mutations that cause increased risks for cancer. In addition, DNA testing for hereditary cancer risk can produce inconclusive results and fail to determine that a variant (an error in our DNA) increases cancer risk. These limitations impact patients and their families because doctors may not have the information needed to recommend appropriate preventive, early detection steps, or certain therapeutic treatments, and relatives may not be referred for genetic testing and subsequently may not be referred for necessary high-risk surveillance. Adding RNA to DNA testing overcomes these limitations for a substantial number of patients as RNA provides considerably more evidence than DNA alone about whether our DNA has variants that increase cancer risk.

At ASHG, Ambry will present data showing that +RNAinsight both (1) identified new variants that increased cancer risk and that would have been missed with DNA testing alone, and (2) determined whether certain variants actually increased cancer risk even though DNA testing alone would have been inconclusive and left doctors without this crucial information.

"Combining RNA and DNA genetic testing lets more people know they have genetic mutations that increase their risks for cancer, empowering them to take action to better manage their cancer risks," said Tyler Landrith, Ph.D., an Ambry scientist who will present the study. "+RNAinsight is the first major, genetic-testing advancement in over 10 years to increase diagnostic yield for hereditary cancer risk."

Dr. Landrith will present data from a prospective analysis of 1,000 patients who received RNA genetic testing (for up to 18 genes). The data show a relative increase in diagnostic yield of 9.1 percent more than DNA testing alone. Adding RNA genetic testing also resulted in a 5.1 percent relative decrease in the number of patients that would have received inconclusive results with DNA testing alone and would not have learned whether they had increased cancer risk.

The prospective study also validated the accuracy of +RNAinsight, establishing a large control dataset of healthy patients. This dataset allowed Ambry researchers to establish a baseline for benign and disease-causing mutations across the genes tested. Dr. Landrith will address the validation in his presentation.

In addition to the prospective study, Ambry Senior Research Associate Blair Conner, M.S., will present data at ASHG showing that RNA genetic testing provided additional evidence to clarify the interpretation of 15 complex variants in genes associated with increased risks for breast, ovarian, colorectal, uterine, and other cancers. Without RNA genetic testing, these variants would have remained inconclusive. This means that past, current, and future patients who otherwise would not have learned they have increased risks for these cancers will now have crucial information to more precisely tailor their medical management for the prevention, early detection, and treatment of cancer.

"An inconclusive result can be unsettling for patients, especially for patients with a strong family history of cancer. Both clinicians and patients may worry that current technology has missed disease-causing mutations in the genes tested," said Ms. Conner. "These data show how +RNAinsight was able to overcome the technological limitations of DNA genetic testing by turning inconclusive results into actionable information for clinicians to better guide patient care."

+RNAinsight is now available through doctors and genetic counselors around the country. For more information on RNA genetic testing, please go to http://www.ambrygen.com/RNAinsight.

For the full list of studies that will be presented at ASHG, please see below:

Oral Presentations:

Wednesday, October 16, 1:00PM - 2:00PM Session 112, Room 310A, Level 3, Convention Center Exome and RNA-based Sequencing Methods for Variant Interpretation to Improve Clinical Utility1:15PM | #197High-throughput RNA splicing profile increases detection of clinically-actionable variants while reducing inconclusive results in patients with hereditary cancer predisposition. T. Landrith, B. Li, A. Cass, B.R. Conner, S. Wu, H. Vuong, S. Charpentier, J. Burdette, H. LaDuca, T. Pesaran, J. Rae-Radecki Crandall, H. Lu, B. Tippin-Davis, A. Elliott, R. Karam. 1:45PM | #225Reclassification of splicing VUS in neurological disease genes via RNA-seq. S. Ichikawa, B.R. Conner, S. Wu, R. Karam.

Poster Presentations:

Poster# 990W: Wednesday October 16, 2:00PM - 4:00PMLeveraging tumor characteristics to predict germline variant pathogenicity in mismatch repair genes. S. Li, D. Qian, B.A., Thompson, S. Gutierrez, T. Pesaran, H. LaDuca, H. Lu, E.C. Chao, M.H. Black.

Poster# 2449T: Thursday October 17, 2:00PM - 4:00PMRNA-seq identifies structural variants in hereditary cancer genes. B. Conner, M. Richardson, F. Hernandez, T. Landrith, T., McBride, B. Tippin-Davis, R. Karam.

Poster#1454F: Friday October 18, 1:00PM - 3:00PMAccounting for splicing effects in known missense variants improves in silico prediction of deleterious effect. D. Qian, J., Clifford, A. Tchourbanov, Y. Tian, M.H. Black, H.M. Lu, Z. Zhu, S. Li.

ABOUT AMBRY GENETICsAmbry Genetics, as part of Konica Minolta Precision Medicine, excels at translating scientific research into clinically actionable test results based upon a deep understanding of the human genome and the biology behind genetic disease. Our unparalleled track record of discoveries over 20 years, and growing database that continues to expand in collaboration with academic, corporate and pharmaceutical partners, means we are first to market with innovative products and comprehensive analysis that enable clinicians to confidently inform patient health decisions. We care about what happens to real people, their families, and the people they love, and remain dedicated to providing them and their clinicians with deeper knowledge and fresh insights, so together they can make informed, potentially life-altering healthcare decisions. For more information, please visitambrygen.com.

For more information on risk factors for hereditary cancer, please visit cancer.gov's fact sheet on hereditary cancer and genetic testing.

Press Contact:Liz Squirepress@ambrygen.com (202) 617-4662

SOURCE Ambry Genetics

http://ambrygen.com

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University of Utah announces 6 new professorships in health and clinical research funded by the Huntsman family – Salt Lake Tribune

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The contribution is part of ongoing support for chairperson positions at the school that were announced in 2017 when the initial six positions were named. This latest installment comes now after the family said goodbye to Huntsman Sr. in February 2018.

Thanks to the tremendous generosity of the Huntsman family, we are thrilled to be able to honor these outstanding faculty members, said U. President Ruth Watkins in a news release.

Accordingly, the professorships at the U. focus on health and clinical research. The chairpersons will sit for a five-year term, ending in June 2024. Here are the six individuals selected:

Bass is a professor of biochemistry and human genetics. She studies cell growth, too, at the Huntsman Cancer Institute, including the pathways of RNA.

Colman is a professor of neurosurgery who has been nationally recognized for his research. He focuses on the treatment of primary and metastatic brain tumors. And he has taken a special interest in developing new therapies to treat those.

Cummins teaches in the U.'s College of Nursing. Her research interest is on improving health care for patients.

Looper is professor of both organic and bioorganic chemistry who came to the U. in 2007 after studying at Harvard. He studies molecule behavior and how that impacts diseases, such as arthritis, multiple sclerosis and cancer.

Steffen Schmitz-Valckenberg

Schmitz-Valckenberg researches in ophthalmology and visual sciences at the U. He focuses on age-related macular degeneration and performs eye surgery.

Shepherd teaches neurobiology and anatomy and researches how the brains processes malfunction with neurological disorders.

Editors note: Paul Huntsman, a son of the late Jon Huntsman Sr., is the owner and publisher of The Salt Lake Tribune.

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Software and Analytics Company to Deploy Cutting Edge Platform for Leading Fertility Organization – PRNewswire

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AUSTIN, Texas, Oct. 16, 2019 /PRNewswire/ -- L7 Informatics, Inc. ("L7"), a leading software and analytics company for healthcare and life science companies, announces the completion of the Phase 1 implementation of its Enterprise Scientific Platform (ESP) with CReATe Fertility Centre. CReATe, which stands for Canadian Reproductive Assisted Technology is headquartered in Toronto, Canada, and is internationally renowned for its specialized fertility services and ground-breaking research. The organization was seeking a scientific information management platform to streamline and optimize their genomics testing operations.

"We are very honored to be chosen to work with CReATe, they are leaders in the field of assisted reproductive technologies with state-of-the-art laboratory facilities and pioneering research scientists," said L7 CEO & President, Vasu Rangadass, Ph.D. "In connection with these high standards, we feel ESP is the ideal platform to streamline the overall Reproductive genomic lab processes by integrating with multiple laboratory instruments, managing complex sample provenance, managing sample storage, inventory, and automating a multitude of important tasks such as bar code printing and clinical report generation."

This project is being completed in four phases and focuses on configuring workflow chains and supporting models (sample types, procedures, etc.) to support four of the array of tests performed by CReATe Reproductive Genomic Lab: PGT-A, PGT-M/PGT-SR, POC testing, and Focused carrier screening. L7's ESP fosters process orchestration and expedites clinical diagnostics by building an integrated, instrument agnostic platform to manage scientific processes and data in one place and yielding better access to the data and results.

"L7's ESP has enabled us to bring patient clinical information from our EMR at the click of a button, and to track laboratory operations meeting OLA and CAP regulations, using its powerful audit trail and provenance history capabilities," mentioned Svetlana Madjunkova MD, PhD., Director of Reproductive Genetics Department at CReATe. Adding, "It's truly a game-changer and will contribute to the advancement of our IVF clinical operations and research."

L7 Informatics and CReATe are also excited to announce that they will be speaking together about their work at the upcoming 2019 American Society of Human Genetics (ASHG) Conference in Houston, Texas. They will partake in a Data CoLabs presentation titled "IVF in silico: fertilization assistance by facilitating clinical and research collaboration" on Wednesday, October 16th at 12:45 pm in CoLab Theatre 2 on the exhibit floor. Robert Zeigler, Ph.D., Director of Customer Solutions for L7 and Dr. Madjunkova will walk the audience through the project, highlighting best-in-class practices.

About L7 InformaticsOur mission is to revolutionize scientific information management to accelerate discoveries and drive higher quality of healthcare. Our end-to-end solutions and services yield efficiencies that enable researchers to make more breakthroughs and healthcare companies to provide superior care. To learn more about L7's Enterprise Science Platform, please go to https://www.l7informatics.com/esp/

About CReATe IVFCReATe Fertility Centre mission is to provide state of the art and compassionate care in a safe environment for our patients and staff; undertake innovative research and provide excellent teaching and mentorship. To learn more about CReATe Fertility Centre, please go to https://www.createivf.com/

Media Contact:Jessica TobeySpeaks Marketing Group LLCJessica@Speaksmarketing.com

SOURCE L7 Informatics, Inc.

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Top Researchers to Present Discoveries Made Possible by Bionano’s Saphyr System for Genome Imaging Technology at the ASHG 2019 Annual Meeting -…

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SAN DIEGO, Oct. 16, 2019 (GLOBE NEWSWIRE) -- Bionano Genomics, Inc. (Nasdaq: BNGO) today announced that disease researchers using Bionanos Saphyr system for whole genome imaging will present their results at the American Society of Human Genetics (ASHG) Annual Meeting, between October 15-19 in Austin, Texas.

The impact of analysis using the Saphyr system for ultra-sensitive and ultra-specific genome-wide detection of structural variation will be presented at ASHG with 22 oral and poster presentations and an Educational Event hosted by Bionano.

ASHG 2019 represents a milestone for Bionano, with a record number of presentations demonstrating novel discoveries through our genome mapping technology, said Erik Holmlin, Ph.D., CEO of Bionano. The growing use of the Saphyr system in disease research illustrates the value in identifying genomic variations for deep understanding of disease origin and diagnostic development.

Optical mapping through Saphyr enables the direct observation of large genomic variations through imaging of fluorescently labeled, megabase-size native DNA molecules. Next-generation sequencing (NGS), in contrast, relies on short-reads that piece together sequence fragments in an attempt to rebuild the actual structure of the genome. NGS often misses large DNA variations, such as deletions, insertions, duplications, and translocations and inversions. Genome mapping resolves these structural variations for more insight into the genetic variations that cause disease.

Below is a summary of key presentations to be given at ASHG 2019 featuring the use of optical genome mapping:

Genetic diagnosis of sex development disorders through optical mappingHalf of disorders of sex development (DSD) patients lack a firm diagnosis. Prof. Eric Vilain, from George Washington University and Childrens National Medical Center, will present research validating the diagnostic and gene discovery use of Bionano genome mapping to identify structural variants in patients with DSD. The talk, entitled Integration of optical genome mapping and sequencing technologies for identification of structural variants in DSD, will be presented on Wed. Oct. 16 at 5:15 - 5:30 pm in the convention center Level 3, Room 361D.

Genomic mapping has the potential to replace a combination of current cytogenetic techniquesCurrently, a comprehensive clinical analysis of genomic aberrations requires a combination of various assays such as CNV-microarrays, karyotyping and fluorescence in situ hybridization (FISH). Dr. Tuomo Mantere, from Radboud University Medical Center, will present data directly comparing traditional cytogenetic assays with Bionano mapping in leukemia patient samples to illustrate that genome mapping can identify all aberrations found by the three conventional technologies combined, and additional variants as well. The poster, entitled Next-generation cytogenetics: High-resolution optical mapping to replace FISH, karyotyping and CNV-microarrays will be presented on Thurs. Oct. 17, between 2 - 3pm, PgmNr 2533/T.

Genomic architecture reveals critical factors that may contribute to schizophrenia-associated 3q29 chromosomal deletionDeletions at the 3q29 chromosomal locus are associated with a 40-fold increase in risk for schizophrenia. Knowing the features that contribute to genomic instability is critical for identifying risk factors of chromosomal deletions. Trenel Mosley, from Emory University, will present the discovery of novel genomic structural characteristics found in 12 patients with 3q29 deletion and their parents using Saphyr. The poster entitled, Optical mapping of the schizophrenia-associated 3q29 deletion reveals new features of genomic architecture, will be presented on Wed. Oct. 16, between 2 - 3pm, PgmNr 1389/W.

Bionano and NGS resolve complex rearrangements in extrachromosomal, circular DNA in glioblastoma The rapid growth of aggressive tumors such as glioblastoma is partially caused by the rapid amplification of oncogenes in circular structures outside of native chromosomes. Because these structures do not occur in the reference genome, standard analysis methods fail to correctly assemble them. Jens Luebeck, from the University of California, San Diego, demonstrates that a combination of Bionano genome mapping and NGS resolves important breakpoints and gene amplifications in extrachromosomal DNA. The talk, entitled Integrated Analysis of NGS and Optical Mapping Resolves the Complex Structure of Highly Rearranged Focal Amplifications in Cancer, will be presented on Sat. Oct. 19, from 10:15 - 10:30am PgmNr: 323

Bionano Educational Event will feature research on muscular dystrophy, prenatal development & neurodegenerative disordersAt Bionanos educational event, Dr. Alka Chaubey from Perkin Elmer Genomics, Dr. Frances High from Mass General Hospital for Children, and Dr. Mark Ebbert from the Mayo Clinic will present findings from their work using the Saphyr system for structural genomic resolution. Analysis of chromosomal repeats, complex genomic haplotypes, and risk loci found in genetic disease will be highlighted by the speakers. Entitled Resolving Structural Variants Across the Whole Genome to Power Your Next Discovery in Human Genetics, the event will take place on Thurs. Oct 17, from 12:45 - 2:00pm at the Marriott Marquis, Houston, River Oaks, Level 3, and include a complimentary lunch.

Additional presentations featuring optical genome mapping:

High Throughput Analysis of Tandem Repeat Contraction Associated with Facioscapulohumeral Muscular Dystrophy (FSHD) by Optical MappingPresented by Jian Wang, Bionano GenomicsWed. Oct. 16, 2 - 3pm PgmNr: 2535/W

Full Genome Analysis for Identification of Single Nucleotide and Structural Variants in Genes that Cause Developmental DelayPresented by Hsiao-Jung Kao, Academia SINICAWed. Oct. 16, 2 - 3pm PgmNr: 2547/W

A Robust Benchmark for Germline Structural Variant DetectionPresented by Justin Zook, National Institute of Standards and TechnologyWed. Oct. 16, 2 - 3pm PgmNr: 1695/W

De Novo Genome Assembly and Phasing for Undiagnosed ConditionsPresented by Joseph Shieh, University of California, San FranciscoWed. Oct. 16, 2 -3 pm PgmNr: 2529/W

Bionano Prep SP Isolates High Quality Ultra-high Molecular Weight (UHMW) Genomic DNA to Improve Research of Cancer and Undiagnosed DisordersPresented by Henry Sadowski, Bionano GenomicsWed. Oct. 16, 3 - 4pm PgmNr: 2598/W

nanotatoR: An Annotation Tool for Genomic Structural VariantsPresented by Surajit Bhattacharya, Childrens National Medical CenterWed. Oct. 16, 3 - 4pm PgmNr: 1506/W

Detection, Characterization, and Breakpoint Refinement of Balanced Rearrangements by Optical Mapping in Clinical CasesPresented by Alex Hastie, Bionano Genomics + LabCorpThurs. Oct. 17, 2 - 3pm PgmNr: 2569/T

Genetic/epigenetic Diagnosis of Facioscapulohumeral Muscular Dystrophy (FSHD) via Optical MappingPresented by Yi-Wen Chen, Childrens National Medical CenterThurs. Oct. 17, 2 - 3pm PgmNr: 2533/T

Comprehensive Analysis of Structural Variants in Clinical Cancer SamplesPresented by Ernest Lam, Bionano GenomicsThurs. Oct. 17, 3 - 4pm PgmNr: 1060/T

Advanced Structural Analysis of CDH Risk Loci with Optical Genome Mapping TechnologyPresented by Mauro Longoni, Massachusetts General HospitalThurs. Oct. 17, 3 - 4pm PgmNr: 2578/T

Structural Variants Associated with GWAS SNPs Provide Mechanistic Explanation of Phenotypic AssociationsPresented by Seth Berger, Childrens National Medical CenterThurs. Oct. 17, 3 - 4pm PgmNr: 2254/T

The Complete Linear Assembly and Methylation Map of Human Chromosome 8Presented by Glennis Logsdon, University of WashingtonFri. Oct. 18, 1 - 2pm PgmNr: 1703/F

High Throughput High Molecular Weight DNA Extraction from Human Tissues for Long-read SequencingPresented by Kelvin Liu, CirculomicsFri. Oct. 18, 1 - 2pm PgmNr: 1769/F

Optical Mapping for Chromosomal Abnormalities: A Pilot Feasibility Study for Clinical UsePresented by Gokce Toruner, UT MD Anderson Cancer CenterFri. Oct. 18, 1 - 2pm PgmNr: 2447/F

Comprehensive Detection of Germline and Somatic Structural Mutation in Cancer Genomes by Bionano Genomics Optical MappingPresented by Mark Ebbert, Mayo ClinicFri. Oct. 18, 2 - 3pm PgmNr: 1760/F

Dark and Camouflaged Genes May Harbor Disease-relevant Variants that Long-read Sequencing Can ResolvePresented by Andy Pang, Bionano GenomicsFri. Oct. 18, 2 - 3pm PgmNr: 1814/F

Bionano Genomics Sample to Answer Workflow for Single Molecule Analysis of Variation in Genome StructurePresented by Sven Bocklandt, Bionano GenomicsFri. Oct. 18, 2 - 3pm PgmNr: 1838/F

Draft Assembly of an Armenian GenomePresented by Hayk Barseghyan, Childrens National Medical CenterFri. Oct. 18, 2 - 3pm PgmNr: 2342/F

About Bionano GenomicsBionano is a life sciences instrumentation company in the genome analysis space. Bionano develops and markets the Saphyr system, a platform for ultra-sensitive and ultra-specific structural variation detection that enables researchers and clinicians to accelerate the search for new diagnostics and therapeutic targets and to streamline digital cytogenetics, which is designed to be a more systematic, streamlined and industrialized form of traditional cytogenetics. The Saphyr system comprises an instrument, chip consumables, reagents and a suite of data analysis tools. For more information, visit http://www.bionanogenomics.com.

Forward-Looking StatementsThis press release contains forward-looking statements within the meaning of the Private Securities Litigation Reform Act of 1995. Words such as may, will, expect, plan, anticipate, estimate, intend and similar expressions (as well as other words or expressions referencing future events, conditions or circumstances) convey uncertainty of future events or outcomes and are intended to identify these forward-looking statements. Forward-looking statements include statements regarding our intentions, beliefs, projections, outlook, analyses or current expectations concerning, including among other things: the timing and content of the presentations identified in this press release; and the ability of genome mapping to perform comprehensive clinical analysis as well as conventional technologies. Each of these forward-looking statements involves risks and uncertainties. Actual results or developments may differ materially from those projected or implied in these forward-looking statements. Factors that may cause such a difference include the risks that our sales, revenue, expense and other financial guidance may not be as expected, as well as risks and uncertainties associated with general market conditions; changes in the competitive landscape and the introduction of competitive products; changes in our strategic and commercial plans; our ability to obtain sufficient financing to fund our strategic plans and commercialization efforts; the ability of key clinical studies to demonstrate the effectiveness of our products; the loss of key members of management and our commercial team; and the risks and uncertainties associated with our business and financial condition in general, including the risks and uncertainties described in our filings with the Securities and Exchange Commission, including, without limitation, our Annual Report on Form 10-K for the year ended December 31, 2018 and in other filings subsequently made by us with the Securities and Exchange Commission. All forward-looking statements contained in this press release speak only as of the date on which they were made and are based on management's assumptions and estimates as of such date. We do not undertake any obligation to publicly update any forward-looking statements, whether as a result of the receipt of new information, the occurrence of future events or otherwise.

ContactsCompany Contact:Mike Ward, CFOBionano Genomics, Inc.+1 (858) 888-7600mward@bionanogenomics.com

Investor Relations Contact:Ashley R. RobinsonLifeSci Advisors, LLC+1 (617) 775-5956arr@lifesciadvisors.com

Media Contact:Kirsten ThomasThe Ruth Group+1 (508) 280-6592kthomas@theruthgroup.com

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