Monthly Archives: May 2017

It was right to provide CF drug Orkambi – Irish Times

Posted: May 8, 2017 at 12:02 am

Sir, Anthony McDonnells article Providing Orkambi to CF sufferers will cost lives (Opinion & Analysis, April 24th) needs to be challenged.

The overall thrust of the article is that health resources are finite and in tackling one problem, we are in practice taking money away from somewhere else. His article concludes, At a time when our health system is struggling to stay afloat, we should focus the resources we have, where they can achieve the most good for the greatest number of people possible, rather than cherry-picking people based on how sad their story appears.

Time and time again when the issue of resources for cystic fibrosis services was raised by our association over the past 50 years, we were told such resources were not justified and the many must be prioritised over the few. If our association had accepted these arguments then people with CF would still be dying before they reached primary school in Ireland, as they did 40 years ago. Now thanks to a combination of better hospital services and access to ground-breaking new medications such as Kalydeco and Orkambi, people with CF in Ireland are now expected to live into their thirties or forties.

The Government has entered into at least two major agreements with the pharmaceutical industry in Ireland to reduce the costs of other drug therapies for which Ireland paid over the odds for many decades. The Minister for Health has stated that at least some of this these savings will be used to pay for new and innovative medications. The proposed increased use of generic drugs and bio-similars is estimated at bringing savings of 750 million to the Government. In short, the cost of Orkambi can be met by savings to the existing drugs budget in Ireland.

Orkambi is not only a high-tech drug, but is also an orphan (rare) disease drug therapy. Mr McDonnell fails to take into account the significantly higher research and developments costs and risks associated with developing drugs for rare diseases. Drugs for rare diseases are called orphan drugs because most drug companies feel it is not financially worthwhile to develop such drugs because of the perceived reluctance of government to pay the higher costs associated with such therapies. The successful funding of Orkambi will result in more research and development into rare disease drugs, not just for those with CF but for other rare diseases. In short, the funding of Orkambi will save more lives and not only within the CF community.

While Mr McDonnell acknowledges that other health savings will be made through Orkambi, he does not give these savings sufficient credit. Orkambi has shown to reduce potential hospitalisations by up to 40 per cent. The CF population in Ireland combined spent over 15,000 days in hospital in 2015. Massive savings will be made in the existing health budget.

Ireland is not acting out of kilter with other countries in approving Orkambi. Germany, Austria and the US have already approved Orkambi, with other countries such as France and Italy likely to follow very shortly. Indications are that Ireland got a very good deal that incudes discount on pipeline drugs from the same company that may be even better than Orkambi, a major innovation for which the Government should be congratulated.

We would encourage the Government and the HSE to fully implement the commitments in the National Rare Disease Plan to review the existing HTA/QALY system through which drugs are assessed in Ireland and to develop a system that is more orphan drug-friendly, not just for CF but for patients with other rare conditions such as muscular dystrophy, Alpha One, Huntingtons disease, Battens disease, cystinosis, and the skin condition EB. Yours, etc,

PHILIP WATT,

Chief Executive,

Cystic Fibrosis Ireland,

Lower Rathmines Road,

Dublin 6.

Visit link:

It was right to provide CF drug Orkambi - Irish Times

Posted in Cf | Comments Off on It was right to provide CF drug Orkambi – Irish Times

Game thread: K-Rod blows it again; Tigers lose, 8-6 – Detroit Free Press

Posted: at 12:02 am

Subscribe today for full access on your desktop, tablet, and mobile device.

17

Let friends in your social network know what you are reading about

4:05 p.m., Fox Sports Detroit, WXYT-FM (97.1): Norris takes on A's ace in rubber match out in Oakland

Try Another

Audio CAPTCHA

Image CAPTCHA

Help

CancelSend

A link has been sent to your friend's email address.

A link has been posted to your Facebook feed.

Autoplay

Show Thumbnails

Show Captions

Detroit Tigers pitcher Daniel Norris works against the Oakland Athletics in the first inning Sunday, May 7, 2017, in Oakland, Calif.(Photo: Ben Margot, AP)

When: 4:05 p.m.

Where: Oakland Coliseum, Oakland, Calif.

TV: Fox Sports Detroit.

Radio: WXYT-FM (97.1; other radio affiliates).

Weather forecast: Sunny, 70 degrees.

Probable starting pitchers: LHP Daniel Norris (2-2, 4.00 ERA) vs. RHP Sonny Gray (0-1, 6.00 ERA).

Tigers lineup:

1. Andrew Romine, CF 2. Nick Castellanos, 3B 3. Miguel Cabrera, 1B 4. Victor Martinez, DH 5. Justin Upton, LF 6. Jim Adduci, RF 7. James McCann, C 8. Jose Iglesias, SS 9. Dixon Machado, 2B

Game notes: We'll see how well the Tigers can recover from the gut-punching loss Saturday, where they were an out away from a victory but fell, 6-5, with K-Rod on the mound. The Tigers are againwithout Ian Kinsler (hamstring), but taking the mound today is Norris, who allowed just one earned run on five hits and four walks over six innings on Monday against the Indians, a 7-1 win. Gray is making just his second start of the season after coming off the disabled list with a strained lat muscle. ... Flashback: Six-year anniversary of Justin Verlander's no-hitter in Toronto.

Related:

Joe Jimenez, slowed by back injury, working to be Tigers closer

Detroit Tigers insider: J.D. Martinez could move through rehab quickly

Twitter updates

Can't see the updates?Tap here for live updates.

0:48

0:58

1:31

0:52

1:29

1:09

1:02

0:57

1:06

0:49

0) { %>

0) { %>

Read more:

Game thread: K-Rod blows it again; Tigers lose, 8-6 - Detroit Free Press

Posted in Cf | Comments Off on Game thread: K-Rod blows it again; Tigers lose, 8-6 – Detroit Free Press

Shares in Focus: CF Industries Holdings Inc (CF) – Rives Journal

Posted: at 12:02 am

Traders are taking a closer look at shares of CF Industries Holdings Inc (CF) of late. The 14-day RSI is presently at 53.58, the 7-day is at 64.35, and the 3-day is resting at 80.13. The Relative Strength Index (RSI) is one of various popular technical indicators developed by J. Welles Wilder. Wilder introduced RSI in his publication New Concepts in Technical Trading Systems which was released in 1978. RSI measures the magnitude and velocity of directional price movements. The data is represented graphically by fluctuating between a value of 0 and 100. The indicator is computed by using the average losses and gains of a stock over a certain time period. RSI can be used to help spot overbought or oversold conditions. An RSI reading over 70 would be considered overbought, and a reading under 30 would indicate oversold conditions. A level of 50 would indicate neutral market momentum.

In terms of CCI levels, CF Industries Holdings Inc (CF) currently has a 14-day Commodity Channel Index (CCI) of 193.00. Investors and traders may use this indicator to help spot price reversals, price extremes, and the strength of a trend. Many investors will use the CCI in conjunction with other indicators when evaluating a trade. The CCI may be used to spot if a stock is entering overbought (+100) and oversold (-100) territory.The 14-day ADX for CF Industries Holdings Inc (CF) is 29.02. Many technical chart analysts believe that an ADX reading over 25 would suggest a strong trend. A level under 20 would indicate no trend, and a reading from 20-25 would suggest that there is no clear trend signal. The ADX is typically plotted along with two other directional movement indicator lines, the Plus Directional Indicator (+DI) and Minus Directional Indicator (-DI). Some analysts believe that the ADX is one of the best trend strength indicators available.

Investors may be studying other technical indicators like the Williams Percent Range or Williams %R. The Williams %R is a momentum indicator that helps measure oversold and overbought levels. This indicator compares the closing price of a stock in relation to the highs and lows over a certain time period. A common look back period is 14 days. CF Industries Holdings Inc (CF)s Williams %R presently stands at -7.14. The Williams %R oscillates in a range from 0 to -100. A reading between 0 and -20 would indicate an overbought situation. A reading from -80 to -100 would indicate an oversold situation. Lookingat some moving average levels on shares of CF Industries Holdings Inc (CF), the 200-day is at 28.03, the 50-day is 28.91, and the 7-day is sitting at 26.90. Moving averages can help identify trends and price reversals. They may also be used to help spot support and resistance levels. Moving averages are considered to be lagging indicators meaning that they confirm trends. A certain stock may be considered to be on an uptrend if trading above a moving average and the average is sloping upward. On the other side, a stock may be considered to be in a downtrend if trading below the moving average and sloping downward.

See the article here:

Shares in Focus: CF Industries Holdings Inc (CF) - Rives Journal

Posted in Cf | Comments Off on Shares in Focus: CF Industries Holdings Inc (CF) – Rives Journal

Term ‘political correctness’ used in meaningless fashion – The Nation

Posted: at 12:01 am

Political correctness means different things to different people. To liberals such as myself it means we respect the fact that we live in a world of many different cultures, religions, races and nationalities. It doesn't mean we can't condemn the demented Islamic State. But it does mean we don't use the Islamic State as an excuse to insult every Muslim on this planet. There is also political correctness on the right. For example, its politically correct for conservatives to call abortion murder. Then they support Donald Trump, who cuts off funding to family planning programmes throughout the world, which means there will be millions of more abortions!

You also have politically correct Zionists who slander all critics of Israel as being anti-Semitic.

When you take the term political correctness out of context, the way Wilcox does, and use it to discredit everyone who disagrees with you, the term itself become completely meaningless.

Eric Bahrt

Read the original post:

Term 'political correctness' used in meaningless fashion - The Nation

Posted in Political Correctness | Comments Off on Term ‘political correctness’ used in meaningless fashion – The Nation

Mike Ryder: Is Trumpcare a form of ‘eugenics’? – Boulder Daily Camera

Posted: at 12:00 am

Policies that are designed to force certain "improvements" in the population are called "eugenics" and are generally considered a bad thing, especially since the extremes of Nazi Germany.

Fast forward to present-day United States, where Republicans in the House of Representatives voted for health-care reform last week that would kick an estimated 24 million Americans off their plans and let insurance companies deny coverage for such pre-existing conditions as pregnancy (sucks to be you, moms) and post-traumatic stress disorder (thank you for your service, veterans, now get lost). This gutting of Obamacare and common decency, if passed into law, will hit the poor and middle class while the rich get you guessed it another tax cut.

Who won't be affected? (Besides members of Congress, who always exempt themselves from losing their Cadillac coverage because, well, they can.) Wealthy white men won't be affected, the kind who acquire young trophy wives so they can favor future generations with their superior bloodlines.

So how is the Republican plan not eugenics?

Mike Ryder

Louisville

Read more:

Mike Ryder: Is Trumpcare a form of 'eugenics'? - Boulder Daily Camera

Posted in Eugenics | Comments Off on Mike Ryder: Is Trumpcare a form of ‘eugenics’? – Boulder Daily Camera

‘Orphan Black’ stars discuss the ethics of cloning | | iosconews.com – Iosco County News Herald

Posted: May 7, 2017 at 11:59 pm

MIZ016>036-041-042-081200-/O.CON.KAPX.FZ.W.0002.000000T0000Z-170508T1200Z/Emmet-Cheboygan-Presque Isle-Charlevoix-Leelanau-Antrim-Otsego-Montmorency-Alpena-Benzie-Grand Traverse-Kalkaska-Crawford-Oscoda-Alcona-Manistee-Wexford-Missaukee-Roscommon-Ogemaw-Iosco-Gladwin-Arenac-Including the cities of Petoskey, Cheboygan, Rogers City, Charlevoix, Northport, Mancelona, Gaylord, Atlanta, Alpena, Frankfort, Traverse City, Kalkaska, Grayling, Mio, Harrisville, Manistee, Cadillac, Lake City, Houghton Lake, West Branch, Tawas City, Gladwin, and Standish1002 PM EDT Sun May 7 2017...FREEZE WARNING REMAINS IN EFFECT UNTIL 8 AM EDT MONDAY...* TEMPERATURE...Widespread temperatures in the mid to upper 20s are expected tonight. The coldest readings will be found in low lying areas away from the immediate Great Lakes shorelines where temperatures may drop into the lower 20s.* IMPACTS...Sensitive vegetation will be damaged or killed if proper precautions are not taken. PRECAUTIONARY/PREPAREDNESS ACTIONS...A Freeze Warning means sub-freezing temperatures are highly likely. These conditions will kill crops and other sensitive vegetation.&&$$

Here is the original post:

'Orphan Black' stars discuss the ethics of cloning | | iosconews.com - Iosco County News Herald

Posted in Cloning | Comments Off on ‘Orphan Black’ stars discuss the ethics of cloning | | iosconews.com – Iosco County News Herald

The evolution of Lucy Liu – CBS News – CBS News

Posted: at 11:59 pm

As her artwork makes clear, it's hard to put a "label" on Lucy Liu. Actress, director, artist, and single mother ... not so simple, as our Mo Rocca discovered:

Actress Lucy Liu showed Rocca around the set of her series, "Elementary": "This is a precinct which is where we shoot a lot. There's a bathroom here but it actually goes out into the morgue. So if you go to the bathroom, you end up in the morgue!"

For CBS' take on Sherlock Holmes, Watson is a woman, played by Liu.

The "Elementary" actress and artist continues to grow, taking on directing and motherhood.

CBS News

But that's not the series' only distinguishing feature. While the dynamic of traditional Holmesian drama is that Sherlock is brilliant and almost infallible while Watson is worshipful and tagging along, it's different here.

"Sherlock is fallible," Liu said. "He's got an addiction problem. She started with him as a sober companion, and then it's turned into a partnership.

"I think it's fair to say it's a much quieter role. It's a role that I have learned patience with. I've had many roles that are quite fiery, and have had a lot of exclamation points after the name. So I think it's nice to change it up a little bit!"

Yes, it's definitely a change from the rock-'em-sock-'em roles she's played in movies. And it's the first that's connected with one fan in particular.

"So is this the first thing that your mother has really grooved to?" asked Rocca.

"Absolutely! Yeah. No hesitation. No hesitation," Liu replied. "This show she understands. She was a huge 'Columbo' fan. Now I've made it big time, because I'm on a detective show!"

Liu was raised in the New York City borough of Queens, speaking Chinese while growing up. "And then when my sister when to school, we started speaking a little bit of English, so it was sort of a little 'Chinglish,' a little mixed bag."

Lucy Liu outside her childhood home in Queen, New York.

CBS News

Her parents emigrated from China. She said, "They are definitely people that worked very hard, and had that whole idea of the American dream, and they pursued it."

But she kept her dream of acting a secret when she went off to the University of Michigan, where she auditioned for a production of "Alice in Wonderland" -- and was cast in the lead role.

"It was shocking,:" Liu said. "I thought there was a mistake, a big mistake. I kept following the name to the character. And I was in shock.

"Growing up as somebody from another country, really, not what you see on television, I never saw myself in the forefront, ever. We were always in the background."

Lucy Liu with Taye Diggs in "Ally McBeal."

Fox

But soon after moving to L.A., Liu would get used to being in front of the camera.

She recalled going to an audition for the series "Ally McBeal": "Everyone was basically Caucasian. And there was me, and then there was, like, one African American person. So I was like, 'Okay. So they're just doing this for the census!'"

Lucy didn't get the part she auditioned for, but series creator David E. Kelly was impressed, and wrote a role just for her, the acerbic Ling Woo. "A lot of people said that she was a bitch. But I felt that she was a very honest and very unmasked person, and was very direct."

View original post here:

The evolution of Lucy Liu - CBS News - CBS News

Posted in Evolution | Comments Off on The evolution of Lucy Liu – CBS News – CBS News

How the Good Emerges Out of Evolution (Second in the Series, A Better Human Story) – Blue Virginia (press release) (blog)

Posted: at 11:59 pm

The first installment of this series can be found here.

Secularization and Its Disconnections

I claimed, in the first entry of this series, that a meaningful story about our kind (about the human saga) is largely missing in contemporary societyat least in its secular components. That phrase about secular components was an acknowledgment that our traditional religions do continue to offer stories that, if believed, provide an account of what we are as human beings and, at least in some respects, the meaning of the human saga.

But over recent generations, in the Western world, much of the world of serious thought has split off from the world of traditional religion. For people who feel that intellectual integrity requires that conclusions be based on applying reason and logic to the totality of the evidence and for whom beliefs based on received authoritative texts fail to meet that test the stories told by the religions of our civilization no longer provide convincing answers.

This process of secularization has left some important empty spaces. An important aspect of such empty space is that, to many, the requirements of intellectual responsibility have seemed to block the way toward firm moral beliefs and spiritual conviction.

But I maintain that there is a secular and intellectually responsible way to fill those empty spaces, or at least some of those that matter most.

Most of secular thought, for example, operates from the conclusion that judgments of value are lacking in a solid basis in reality. (You cant get ought from is.) Statements about value, many have felt compelled to conclude, are just matters of opinion, and thus cannot be taken fully seriously as saying things that are true.

Additionally, according to much of the rational-secular world, there is no meaningful and valid way of speaking of the sacred.

It has seemed to many that one can EITHER be intellectually responsible (meaning believing only what evidence and reason lead one to believe) OR one can feel hold moral and spiritual truths with full conviction. But not both.

That way of thinking, I maintain, is both dangerous and invalid.

Those empty spaces left empty by the way secular thought has developed have contributed to the peril of our times by interfering with the ability of many good people to connect fully with their moral and spiritual core.

That is a significant loss, as that core is a place from which comes much of the passion required to contain the forces of destruction at work in the world.

(Heres a dangerous combination that might serve as a very approximate description of the heart of the current crisis in the American body politic: while a large component of the church-going part of America, which does believe in such things as good and evil, has been deceived and manipulated into giving support to a force of destruction; and meanwhile, a large portion of the secular-minded, liberal part of America has proved incapable due to its blindness and weakness of seeing and combating that force.)

If it is true that the disconnection, among many with a secular worldview, from a moral and spiritual core is part of the reason that destructive forces have gained so much power in our times, it would be hard to over-estimate the importance of this issue.

And if a different and valid path for secular thought were available one that demonstrates that there is no need to choose between maintaining intellectual integrity (in rational, scientific terms) and having full commitment to some fundamental moral and spiritual truths then that different way of thinking could have an important and beneficial effect on the quality of our civilization.

It is the belief in that different and valid path, and its potentially beneficial effects, that is the motivating force behind this series on A Better Human Story.

So, to return to my sales pitch for the integrative vision being offered in this series:

Would you be interested in a way of understanding our humanity that offers a well-reasoned, empirically-based, intellectually responsible way of understanding that offers a meaningful way to see the realm of value categories like good and evil, right and wrong, and even the sacred as an essential and real part of our human reality?

****************************

Evolution As a Meaningful Story

To begin to chart the way toward filling those empty spaces.

At the heart of the secular understanding of who we are, and how we got here, is the story of the evolution of life on earth. Science says clearly, this is how we came to be.

For many, this evolutionary view in which the living world is shaped by a process with an apparently wholly impersonal and opportunistic modus operandi has seemed to strip our being of some of its important meanings. Like the reality of good and evil. Like a dimension worthy of calling the sacred.

But theres another way of comprehending that evolutionary view.

The story of evolution, far from closing off our access to the important moral and spiritual spaces that religions have filled with their different stories, provides us a meaningful way to understand the reality of the good and the sacred.

It is on those positive dimensions that this installment will focus. But in a subsequent entry, I will show how that same perspective provides the necessary context for understanding how as a consequence of our species rather recent breakthrough into civilization, after four billion years of the story of life on earth humankind inadvertently unleashed a force that might reasonably be called evil into our world.

There are two reasons that it is the positive part of that pair how evolution gives rise to the good that should come first. It comes first chronologically, in terms of how value gets built into the organic structure of creatures such as ourselves. And it should come first also logically, in terms of laying the necessary foundation for seeing how the subsequent breakthrough into civilization of a culture-creating animal like homo sapiens would inevitably generate a force of brokenness.

***************************

The Good as an Emergent Reality

From the secular perspective, it appears that values like the good and the sacred are not built into the cosmos, out there. But those values are emergent realities arising out of the evolutionary process. Realities that have been instilled, by that process, into our very being.

In a nutshell, here is the argument for how one can get from the realm of objective reality, that science presents, to the realty of the good.

(Those first two points are fairly basic in the realm of evolutionary thought, though the language about choosing life over death and finding fulfillment are my own way of framing those ideas. The third idea has a degree of kinship with the philosophical idea of utilitarianism. Taken together, they form the framework for an argument well, I wouldnt know how to counter it!)

What is selected for, in biological evolution, are those creatures that do what survival requires. At a certain point in evolutionary development, that required doing starts being driven by motivation. Wanting to do whats necessary for survival helps. Wanting to avoid what threatens survival is also a plus.

Along with motivation, then, comes this wanting. Which, in turn, means emergence of an experiential dimension of things mattering. To the motivated creature, some outcomes and some experiences are preferred to others.

In this way, evolutions choosing of life over death leads directly to the next step in the emergence of value. That step brings us to that third and crucial point above the one about the connection between value and the fulfillment of sentient creatures.

The Central Reality of the In Here

It mystifies me how so many smart people have stumbled over this movement from this step from the out there domain of objectivity to the in here domain of experience. As if value could not be real unless it was out there. But it seems clear enough to me that value could only make sense in terms of the (subjective) experience of sentient beings, and that it is no less real for that.

The idea that for something to be real it must be objective, like the stars in the heavens or the rock on the road, seems to me a complete non sequitur.

Value means that some things are better than other things. In a lifeless universe, devoid of any beings to whom things matter i.e. for whom some things are experienced as better than others how could there be any kind of value? (A God could count here as one such being, if He were well pleased with one thing, and displeased with another.) But in the absence of any such creatures, and any such experiencing, how could anything be better than anything else?

There can be no value unless something matters something is better or worseto someone.

(In a universe with a God who makes pronouncements about the better and the worse, would that mean that it matters to Him? That He thinks it will be good for His creatures? And for His creatures to accept such pronouncements, would that not have to mean that they accept that Gods assessments. Unless, that is, it is just out of fear or deference to authority. Only in an authoritarian framework does the positing of God solve any problem about value not equally solved in a secular framework.)

And in a universe without a God the universe as cosmological science has been able to see it then one can say that value is an emergent reality in the universe, once creatures (like us, but not only us) emerge to which some experiences are preferable to others.

In sum: Value is inherent in the experience of creatures like us, and value must necessarily register in the domain of experience.

At this point, we might encounter the challenge according to which experience, being subjective, cannot be really real. To which my response is: To say that value is not real, because its merely based in experience, makes as much sense as to say that pain is not real.

Nor does subjective mean merely idiosyncratic. Just as it is fallacious to argue from the fact that we each have different bodies that theres no such thing as human anatomy.

Beneath our differences between individuals, between cultures there is a fundamental stratum of our experience, and of our sense of how things matter, on either the positive side or the negative, that is grounded in how evolution has shaped our human nature.

*********************

The Two-Level Game of Evolved Human Life

As it follows from evolution understood as a process that chooses life over death, that the nature of a sentient creature is molded such that its experience of well-being tends to correspond to what, in the history of the species, has been life-serving, so also does it follow that the life-serving and the fulfilling are two sides of the same evolutionary game.

The game of life operates, then, on two levels. The overall system operates mechanically as if animated by the purpose of yielding survival. The sentient creatures the system creates are built to seek fulfillment. From the point of view of the system, that fulfillment is a means to an end. But from the point of view of the sentient creatures, the fulfillment is an end in itself.

************************

Out of the impersonal processes of evolution, there emerges value, which is to say, there emerge creatures who experience things in terms of the better and the worse.

It matters to a baby whether it is lovingly cared for our callously neglected or cruelly abused. It matters to a kitten whether it is stroked or tortured. (Pleasure and pain are a gross way of expressing the inherent dichotomy. But I think the experiential good is richer than pleasure connotes. The word fulfillment captures more of that richness.) It matters to a human community whether the people flourish or are mired in misery.

The emergence of creatures who directly experience that things matter is the entirely logical one might say inevitable outcome of the process of natural selection. Once life begins to develop out of a cosmos in which, at least as far as science can tell, there was previously no meaningful way in which one thing could be better than another, the good will eventually arise as an emergent property.

Filling Those Empty Spaces in an Entirely Secular Way

Thus does a scientific, secular perspective provide a meaningful way of recognizing the reality of value. This way of establishing that reality seems by no means inferior logically to any of the religious stories that claim to illuminate the good and the evil.

As the human good consists of human flourishing, this secular way of establishing value is fully capable of establishing the validity of such principles as Love thy neighbor as thyself, said by Jesus, or Rabbi Hillels precursor to the Golden Rule, What is hateful to you, do not do to your fellow. For the practice of such precepts will maximize the fulfillment of the human beings within any community that practices them. Their rightness is affirmed by the experiential reality of sentient creatures.

As value is an emergent property in the evolving system of life, so also is the sacred.

Just as value cannot have meaning except in terms of experience, so also with the sacred. (Unless within a basically authoritarian outlook, in which anything the Supreme Being declares, His creatures must agree to.) Consider the sacred as what occasions a special form of the experience of value value to the nth degree. Value in excelsis.

Many with a secular perspective regard the concept of the sacred as meaningless, as not corresponding to anything in reality. But to deny the meaningfulness of the idea of the sacred is to deny an experiential human reality.

The reality is that it is a human universal that people have special kinds of experiencesexperiences that give rise to a sense of sacredness. We need some such concept, because it refers to an experiential reality that people talk about in such termsin terms of its breaking through into a deeper, more illuminated, bigger dimension of reality.

The sacred the capacity for this kind of experience seems to be an inherent part of our humanity. Just as music and laughter which are also found everywhere human beings are to be found are part of what we humans are by nature. Evolution, evidently, put it there.

To deny the reality of the sacred because it is grounded in experience makes as much sense as denying the reality of excruciating pain.

Not every human being, it seems, has such Wow way out there blown away deeply illuminated kinds of experience of value. But I gather its a substantial portion. (Not every human is musical, or has a sense of humor either.)

The sacred seems to be a human universal in the sense that such experiences arise in virtually every human culture. And, in virtually every human culture, people attribute profound importance to such experiences. Indeed, historically and cross-culturally, it would seem that human cultures have organized themselves around such experiences.

And perhaps in that major orienting role that these experiences play, we get a clue to how it may be that the evolutionary process which instills value in all sentient creatures has apparently instilled that experiential capacity in humankind. One might presume that it has proved life-serving for the animal that embarks on the path of culture to possess a capacity for experiences of value so profound that those experiences serve as major guideposts for the organization of cultural life.

Indeed, what peoples through history and across the world have tended to experience as sacred are things that are profoundly life-serving: the sacredness of holding ones infant in ones hands, the beauty of the natural world from which we draw our sustenance, the solidarity of the social group, the family gathered around the Thanksgiving table, ones hearth and home, a well-ordered and just social order.

The sacredness, in other words, of those things that contribute to human flourishing.

The Sacred: A Case in Point

Which will lead, in the next installment, to my talking about the latest space Ive been working on fleshing out for this ambitious integrative vision of a Better Human Story.

In contrast to that fleshed out piece mentioned in the previous piece the darkness ascendant in American in these timesthis new project is about something worth celebrating in human life.

The name of the new project is The Sacred Space of Lovers.

XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX

NOTE: Do you want to follow this series? If so, please sign up for newsletter here to be informed whenever a new entry in this series is posted.

Are there people you know who would answer yes to the question with which this piece began? If so, please send them the link to this piece.

XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX

NOTE: The comments that follow, below, are from people Ive asked to serve as my co-creators on this project, i.e. to help me make this series as good and effective as possible.

They are people who have known me and my work. And my request of them is that when the spirit moves them to contribute they add what they believe will help this series fulfill its purpose and give the readers something of value. Ive invited them to tell the readers what they think will serve the readers well, and to pose questions or challenges they believe might elicit from me what I should be saying to the readers next.

I am grateful for their attempting to help me find the right path.

Margee Fabyanske:

Im ready to accept a new way of understanding that offers a meaningful way to see the realm of value (right/wrong, good/evil, or sacred/fulfilling) as an essential and real part of our human reality. But should we group people into two vast categories of secular intellectual vs. religious fundamentalist?

If evolution has shaped our human nature should we jump to the conclusion that all humanity is looking for the sacred or fulfilling life as part of our DNA? Do we all, deep down, want to flourish?

Andy Schmookler responds:

On your first question:

Reality is of course more complicated than our categories. But our understanding does seem to require that we notice differences, and one important difference is that different people reach their beliefs by different means. In other words, they have different epistemologies.

This series is dedicated to the approach to knowledge/belief that is about evidence processed through reason. The belief in biological evolution grows out of a veritable mountain of evidence of many different kinds.

The religious approach and please note that I said nothing about fundamentalism is usually different. Certainly scientific proof of Gods existence is lacking. And the purely logical attempts to prove it as attempted by Aquinas for example fail to pass logical muster. I expect that most people who believe in God (or believe, say, that one can find salvation in Jesus Christ) have arrived at that belief by means quite other than evidence processed by reason.

It is true that a person might believe in God through that means. If, for example, one had the experience that Moses is reported to have had with a voice speaking to him out of a bush that burned but was not consumed, that experience would constitute for that person evidence (even if not of a publicly available sort), and reason might lead him/her to conclude that indeed, God does exist. (Or they might conclude that theyd been hallucinating.)

I myself would like to believe that the universe is ruled by a God who is just, merciful, good, powerful, wise, etc. as our traditional Western religions have posited. For me, however, the evidence does not seem to support that belief. On the other hand, I also have had some experiences that I have difficulty integrating into my general worldview, and leave me open to the possibility that there is more in heaven and earth than is dreamt of in my (natural) philosophy.

On your second question:

I am in general against jumping to conclusions. But if there are people who are inherently indifferent to the pursuit of happiness, I would be at a loss to explain why. And that would be for the reasons articulated in the piecei.e. how selection has crafted us to do what survival requires, and to feel rewarded (fulfilled) for doing those things.

There certainly seems a wide range of human variation. It seems to me quite plausible that seeking experience of the sacred value to the nth degree is not a human universal, just like not everyone responds deeply to music. (Also, there can be birth defects of all kinds.) And certainly people can be damaged by their experience so that they do not remain alive to the possibilities of happiness, pleasure, fulfillment.

But how would it come to pass that someone would by inborn nature not be inclined toward that which his/her ancestors were selected for being motivated and rewarded for pursuing?

************************

Fred Andrle:

Atheists and agnostics I know admittedly a small number have firm moral beliefs and a motivation toward altruistic action based in compassion for their fellows. I dont find them at all hesitant in this regard. Perhaps they base their beliefs in a kind of thought process similar to yours. I will inquire.

One atheist friend holds that we have developed our sense of altruism, our sense of compassion, even love, out of a need to function as a human society. Without that development, he says, societies would collapse in an orgy of personal greed and comprehensive exploitation of others.

So I wonder why some who dont subscribe to a religious outlook find it so difficult to leap to a firm secular code of ethics. I wonder whats missing for them.

And one atheist friend who has had an ecstatic experience of the sacred looks back on what was for him at the time a religious experience, and now calls it brain chemistry. That seems enough of a value for him. Sufficient in itself because the experience was intensely life affirming.

Excerpt from:

How the Good Emerges Out of Evolution (Second in the Series, A Better Human Story) - Blue Virginia (press release) (blog)

Posted in Evolution | Comments Off on How the Good Emerges Out of Evolution (Second in the Series, A Better Human Story) – Blue Virginia (press release) (blog)

Researchers map the evolution of dog breeds – Clinton Herald

Posted: at 11:59 pm

Finally, Fido has a proper family tree.

Genetic researchers have assembled the most definitive evolutionary tree of dogs using gene sequences from 161 modern breeds. The map of dog breeds and how they are related, the largest to date, may eventually help researchers identify disease-causing genes in dogs and humans.

The study was published April 25 in Cell Reports.

Researchers found new evidence that dogs traveled with Native American ancestors who crossed the Bering Strait. Scientists have previously reported that such a New World Dog existed, but this study marks the first time genetic evidence of this ancient canine sub-species has been identified in modern breeds.

Some dogs from Central and South America, including the Peruvian Hairless and the Xoloitzcuintle, are likely descended from the New World Dog. These breeds are genetically distinct from popular breeds in American, most of which are of European descent.

"What we noticed is that there are groups of American dogs that separated somewhat from the European breeds," said study co-author and dog geneticist Heidi Parker of the Nation Institutes of Health. Weve been looking for some kind of signature of the New World Dog, and these dogs have New World Dogs hidden in their genome.

Its unclear precisely which genes in modern hairless dogs are from Europe and which are from their New World ancestors, but the researchers hope to explore that in future studies.

The large genome dataset the geneticists assembled, including pure breeds sampled from around the globe, helped them account for mechanisms that led to the formation of modern breeds. The researchers propose that breed creation was a two-step process: dogs were bred first to fill certain functional roles, then for certain physical attributes.

First, there was selection for a type, like herders or pointers, and then there was admixture to get certain physical traits, said Parker. I think that understanding that types go back a lot longer than breeds or just physical appearances do is something to really think about.

The researchers amassed a dataset of 1,346 dogs originating from all continents except Antarctica. To collect the material for gene sequencing, they attended dog shows and recruited dog owners to participate in the study.

If we see a breed that we havent had a good sample of to sequence, we definitely make a beeline for that owner, said Elaine Ostrander, senior co-author and dog geneticist, also of the NIH. And say, Gosh, we dont have the sequence of the Otterhound yet, and your dog is a beautiful Otterhound. Wouldnt you like it to represent your breed in the dog genome sequence database? And of course, people are always very flattered to say, Yes. I want my dog to represent Otterhound-ness.

The quest continues. More than half the dog breeds in the world today still have not been sequenced and the researchers intend to keep collecting dog genomes to fill in the gaps.

Dogs and people are subject to many of the same diseases, including epilepsy, diabetes, kidney disease and cancer, so understanding dogs genetic history may have practical applications in research, said Ostrander.

Read the original post:

Researchers map the evolution of dog breeds - Clinton Herald

Posted in Evolution | Comments Off on Researchers map the evolution of dog breeds – Clinton Herald

Norfolk teen wins robotics competition award – 13newsnow.com

Posted: at 11:57 pm

Norfolk girl wins robotics competition award

Arrianee LeBeau, WVEC 3:49 PM. EDT May 07, 2017

Chai Hibbert and her robotic creation (Photo: 13News Now)

NORFOLK, Va. (WVEC) -- A junior at Norfolk Academy beat out thousands of students from nearly 30 different countries, taking home a prestigious robotics award.

Last weekend, Marissa ChaiHibbertreceived the Dean's List Award from the 'FIRST' tech challenge in Saint Louis.It stands for "For Inspiration and Recognition of Science and Technology."

In many ways, Chaiis like most teenage girls. She gets a little giddy when she's talking about things she loves... but her love is for robots.

"When I was 10, 11 years old, my dad -- he's an engineer, a captain in the Navy -- we sat down and watched a couple of videos of autonomous robots. And I was just sitting watching the TV and I was like, 'This is so cool. I wanna do this,'" she recalls.

At Norfolk Academy, Chai is part of the Bulldog Robotics Team 8095. This past year with 21 kids on the team, they built this:

(Photo: 13News Now)

"These are the aluminum grabbers that grab the Wiffle balls and have them travel up this track with 3D printed wheels," Chaisays, describing her robotic creation. "We had to have a bunch of balls be able to come up here and shoot out."

She adds, "Once we finally got it, we were so excited."

Chai's team reached the finals this past year at a state FIRST TECH CHALLENGE tournament. She was chosen as one of five students in the state to compete for an award at the international FIRST Championship for robotics in St. Louis.

Out of nearly 15,000 students from 33 countries, only 20 were chosen as winners of the FIRST Dean's List Award.

Chai was one of them.

"I think what really made her distinctive was that she didn't just focus on the robot," says her physics teacher Robert Call. "FIRST is not to be seen just as a robotics program or a robotics competition, but as a program that really teaches kids how to do program and how to run an engineering project."

And sure, being a part of the robotics team is fun for Chai. But she also knows by doing so, she's showing the importance of science, technology, engineering, and math education.

"Just the fact that I have gotten the chance to be a Dean's List winner, I want to make sure that I get this out to as many people as possible," Chai says. "Especially minorities, especially girls, because we can do this!"

No matter what you may fear,Chai says don't be afraid to face it, because you never know what reward may be on the other side.

"Just let go of that fear you have. Be completely calm about it, and enjoy the process," she says.

2017 WVEC-TV

WVEC

Girls Who Code: Local STEM program reaches out to girls

See the rest here:

Norfolk teen wins robotics competition award - 13newsnow.com

Posted in Robotics | Comments Off on Norfolk teen wins robotics competition award – 13newsnow.com