Daily Archives: April 28, 2017

00 Hustle brings cyberpunk to St. Tim’s stage – Cochrane Times

Posted: April 28, 2017 at 3:17 pm

The drama class at St. Tim's is taking a different approach with their spring performance, bringing a student led production to the stage that was worked out between them using different movies to create the cyberpunk 00 Hustle premiering Tuesday May 2.

The basic premise sets 00 Hustle in a peaceful future run by a government that has, for the most part, pacified the populace to the point that they are now called Drones.

They are told they're happy so they're happy, said Shayla Bryant, who plays Jane Bond, a former government agent who left for a less controlled existence only to be reeled back in for a mission to find Ruby Goldberg, a psychotic scientist exiled by the government and now living in the underground society of the Scraps.

From this point the students tell a story of sociological conflict that questions which side is right, or at the very least less wrong, in deciding how a society should be run.

The question is is the government really that bad since it's peaceful, said Bryant, with Ruby's actress Ashlee Rocliffe jumping in to point out the Drones exist without freedom of thought.

If people come in with a clear mind it will make it so much more interesting, added Rocliffe, adding that they all really enjoyed the process of creating a unique story with undertones from so many disparate films.

There's Demolition Man, Inside Out and Batman, said Rocliffe, as well as other films, more Shakespeare than you would expect from a student play and enough swing music and dancing to make up their fight scenes.

It was different because we didn't know where we were going to get to and kept writing, said Rocliffe as everyone wrote different scenes, back stories and characters that got shifted around constantly until their teacher, Kevin McGregor came up with a good ending and they were able to slip everything into place.

For us, it's the experimental learning we get through the program that we enjoy, said Bryant, with the students coming up with quirks for their characters, tragic origins for seemingly one dimensional characters and a couple twists they really hope will take the audience by surprise.

We wanted something new and something [audiences] haven't seen before, said Rocliffe, something they would have accomplished if they stuck with James Bond in a cryber/steampunk world but that promises to be a memorable experience by putting in the effort to make it something that will stick with people after the curtains close.

After doing a show for the kids at Holy Spirit, 00 Hustle will open at 7 p.m. Tuesday May 2 at St. Tim's school and have their final call Friday night. Tickets are available for $10 at the school for the first two shows since they will be serving tacos on Tuesday and wine and presecco on Wednesday, but they will be available at the door for the Thursday and Friday shows.

Dfeil@postmedia.com

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00 Hustle brings cyberpunk to St. Tim's stage - Cochrane Times

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Crowdfund This: Watch the Cyberpunk VR Film HARSH REALITY … – ScreenAnarchy (blog)

Posted: at 3:17 pm

Like dystopian sci-fi cyberpunk tales? Like virtual reality? Check outHarsh Reality!

This short film has already begun production, but the cyberpunk thriller needs your help for completion funds. The story is abouta professional gamer whos been kidnapped and subjected to a mind-altering VR program. It reminds me a little of a certain Black Mirror episode (and even A Clockwork Orangea touch)in both theme and content.Harsh Realityisabout how technology separates us from the consequences of our actions, and on the flip side of the coin, how that same technology connects us to others.

To prep for the film including the commercial writer/director Iain Marcks researched VR, EMDR, media theory, and the political roots of cyber culture. He also consulted Dr. Douglas Rushkoff, an early advocate of open source culture and an influential author, teacher, and documentarian who is associated with the beginnings of cyberpunk. (Dr. Rushkoff has donated some campaign perks and makes a cameo appearance in the film).

Harsh Realityasks: What happens when technology designed to help us is used against us?

Let's find out.ScreenAnarchy has the exclusive on the commercial for the the NSYS-EX, the therapeutic device which serves as the basis of the narrative for the film. (You can see it below.) In the universe ofHarsh Reality, the NSYS-EX is the latest in enhanced psychotherapeutic rehabilitation in a nutshell, its psychotherapy via virtual reality.

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Androids Get a Dose of Neon Chrome as Cyberpunk Shooter … – Develop

Posted: at 3:17 pm

Tampere, Finland, April 27th 2017 - The top-down cyberpunk shooter Neon Chrome is now available for Android devices in Google Play. The game is priced $9.99 USD.

Neon Chrome has proven to be a solidly performing flagship title for us. Im happy the game is now available for Android gamers as well. says Tero Alatalo, CEO of 10tons.

Neon Chrome is an infinite twin-stick top-down shooter with procedurally generated levels and destructible environment. Choose your character, enter the elevator and try to bring down the Overseer - again and again. Neon Chrome is an endless symphony of fight, die, improve and repeat.

Features:

Neon Chrome in Google Play: https://play.google.com/store/apps/details?id=com.the10tons.neonchrome

Neon Chrome mobile trailer: https://youtu.be/YPnDdVvliv0

For more information and assets, see http://neonchromegame.com/ and http://www.10tons.com/Game/neon_chrome.html

Neon Chrome is also available in Steam and for Playstation 4, Playstation Vita, Xbox One, and iOS.

Games Press is the leading online resource for games journalists. Used daily by magazines, newspapers, TV, radio, online media and retailers worldwide, it offers a vast, constantly updated archive of press releases and assets, and is the simplest and most cost-effective way for PR professionals to reach the widest possible audience. Registration for the site and the Games Press email digest is available, to the trade only, at http://www.gamespress.com

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JDA sees bright future in visibility for TMS – DC Velocity

Posted: at 3:16 pm

Technology April 27, 2017

Data science and Internet of Things could predict delays, suggest solutions, JDA says.

By Ben Ames

JDA Software Group Inc. has added capabilities to its Intelligent Fulfillment portfolio that could allow users to connect their supply chain planning and execution processes spanning factories, warehouses, and stores, and someday suggest solutions to freight delays before they happen, the company said.

The updates include changes to JDA's Demand, Fulfillment, Transportation Management, and Warehouse Management platforms, the Scottsdale, Ariz.-based company said during its annual user conference in Las Vegas.

Through these new abilities, JDA's software can tap into new intelligence streams that give visibility into capacity challenges, potential execution bottlenecks, and real-world disruptions that impact the bottom line, Fabrizio Brasca, JDA's vice president, solution strategy, intelligent fulfillment, said in a release. That power is crucial for companies in the digital economy that need to shift from linear, batch-oriented planning to synchronous, constraint-aware planning, Brasca said.

Among other changes, JDA announced deeper integrations between its transportation management system (TMS) and technology partners TransVoyant LLC, FourKites Inc., and Inttra Inc. The deals enable improved carrier connectivity, efficient on-boarding, real-time visibility, and predictive analytics, JDA said. The company also announced forthcoming integrations with new partners MacroPoint LLC and 10-4 Systems Inc. that could give shippers and third-party logistics companies (3PLs) real-time visibility into load status.

The strategy reflects JDA's renewed focus on expanding its software capabilities through deeper relationships with technology partners, a strategy promoted earlier at the conference by JDA CEO Girish Rishi.

For its long-term roadmap, JDA plans to add to the expanded visibility and analytics by equipping its software platforms to generate predictions about future cargo flow and then make automated decisions based on that data, Brasca said in an interview. "Visibility is great, but you need to be able to do something with it," he said. "Don't just tell me where the shipment is, tell me where it's going to be."

In JDA's vision, this approach will pay off with the greatest return when software gains the ability to predict delays or transportation challenges before the truck leaves the distribution center. Armed with that information, a useror the TMS itselfcould then reroute a truck around a planned street protest, or choose a reefer truck instead of a standard trailer if a route was scheduled to pass through a city with unseasonably hot temperatures, Brasca said.

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Edap Tms SA (EDAP) Earns News Sentiment Score of 0.31 – Sports … – Sports Perspectives

Posted: at 3:16 pm

Edap Tms SA (EDAP) Earns News Sentiment Score of 0.31 - Sports ...
Sports Perspectives
News articles about Edap Tms SA (NASDAQ:EDAP) have trended positive recently, Alpha One reports. The research firm, a subsidiary of Accern, ranks the ...
Discounted Stock Alert on EDAP TMS S.A. (NASDAQ:EDAP ...Morgan Research
Zacks Investment Research Downgrades Edap Tms SA (EDAP) to ...BBNS
Edap Tms SA (EDAP) Receives Daily News Impact Rating of 0.31 ...Community Financial News

all 4 news articles »

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Edap Tms SA (EDAP) Earns News Sentiment Score of 0.31 - Sports ... - Sports Perspectives

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Will your computer delete your thoughts? – TRUNEWS

Posted: at 3:16 pm

Thou canst not touch the freedom of my mind, wrote the playwright John Milton in 1634. But, nearly 400 years later, technological advances in machines that can read our thoughts mean the privacy of our brain is under threat. Will your computer delete your thoughts without your knowledge or permission? Experts warn the public about the possibility of this happening sooner than we think.

The Independent reports that two biomedical ethicists are calling for the creation of new human rights laws to ensure people are protected, including the right to cognitive liberty and the right to mental integrity. Pretty alarming news considering that the legal system is still trying to figure out how to protect something as basic as religious freedom. Science is expanding at a speed that surpasses understanding and scientists have already developed devices capable of telling whether people are politically right-wing or left-wing. In one experiment, researchers were able to read peoples minds to tell with 70 per cent accuracy whether they planned to add or subtract two numbers.

Facebook alsorecently revealed it had been secretly working on technology toread peoples minds so they could type by just thinking.And medical researchers have managed to connect part ofa paralyzed mans brain to a computerto allow him to stimulate muscles in his arm so he could move it and feed himself.

The ethicists, writing ina paper in the journalLife Sciences, Society and Policy, stressed the unprecedented opportunities that would result from the ubiquitous distribution of cheaper, scalable and easy-to-use neuro-applications that would make neurotechnology intricately embedded in our everyday life.

However, such devices are open to abuseon a frightening degree, as the academics made clear. They warned that malicious brain-hacking and hazardous uses of medical neurotechnology could require a redefinition of the idea of mental integrity.

We suggest that in response to emerging neurotechnology possibilities, the right to mental integrity should not exclusively guarantee protection from mental illness or traumatic injury but also from unauthorized intrusions into a persons mental wellbeing performed through the use of neurotechnology, especially if such intrusions result in physical or mental harm to the neurotechnology user, the ethicists wrote.

The right to mental privacy is a neuro-specific privacy right which protects private or sensitive information in a persons mind from unauthorized collection, storage, use, or even deletion in digital form or otherwise.

And they warned that the techniques were so sophisticated that peoples minds might be being read or interfered with without their knowledge.

Illicit intrusions into a persons mental privacy may not necessarily involve coercion, as they could be performed under the threshold of a persons conscious experience, they wrote in the paper.

The same goes for actions involving harm to a persons mental life or unauthorized modifications of a persons psychological continuity, which are also facilitated by the ability of emerging neurotechnologies to intervene into a persons neural processing in absence of the persons awareness.

They proposed four new human rights laws: the right to cognitive liberty, the right to mental privacy, the right to mental integrity and the right to psychological continuity.

Professor Roberto Andorno, an academic at Zurich Universitys law school and a co-author of the paper, put out a serious warning:

We need to be prepared to deal with the impact these technologies will have on our personal freedom.

The Independent copy / TRUNEWS summary.

Please contact TRUNEWS with any news tips related to this story. Email: Info@trunews.com

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Researchers advocate neurorights to protect brain data – The Stack

Posted: at 3:16 pm

A neuroethicist and a human rights attorney have proposed that human rights be expanded to guard the sanctity of the human mind in the face of rapid advancements in neuroscience and neurotechnology.

The four rights that are specifically addressed in their research paper, published in the Journal of Life Sciences, Society and Policy are the right to cognitive liberty, the right to mental privacy, the right to mental integrity and the right to psychological continuity.

Rapid advancement in neurosciences has created unprecedented possibilities for accessing data from the human brain. Cutting edge neurodevices include neuroimaging, neurostimulators and brain-computer interfaces that can have clinical research, marketing and even military applications.

The researchers make the case that the growing use and rapid advancements in this type of technology present a legal, ethical and social challenge that may force a reconceptualization of certain human rights or even the creation of a new standard of human rights, which they term neurorights.

The first of the neurorights proposed is the right to cognitive liberty. This refers to the rights of an individual to choose whether or not to use emerging neurotechnologies, protecting them from being forced to use neurotech under coercion or without consent.

The second is the right to mental privacy, in which the team advocates expansion of privacy and data protection regulations to cover neural activity in addition to other types of information.

The third neuroright calls for a reinterpretation of existing guarantees of the right to mental integrity to account for the complexity of issues introduced by neurotechnology. Specifically, the paper focuses on the brain-computer interface, or BCI, which just a week ago was announced as an upcoming feature of Facebook. The Facebook BCI will allow users to post directly from their minds, and may be available as soon as two years from now.

However, a BCI may be manipulated or hijacked, and could involve direct manipulation of a persons neural computation. For this reason, mental privacy and the protection of brain data are at risk, not to mention a persons physical and mental health.

Finally, the right to psychological continuity addresses the right of a person to maintain an individual identity without third-party modifications. Some therapeutic applications of transcranial direct current stimulation, transcranial magnetic stimulation, and deep brain stimulation have been found to be beneficial to patients in research and therapy. In light of this, the right to psychological continuity would protect an individual from being subjected to this type of stimulation without consent, or by protecting the underlying neural functioning, should one choose to participate in this type of neurostimulation.

Marcello Ienca, co-author of the paper and a neuroethicist at the University of Basel, told the Guardian, The question we asked was whether our current human rights framework was well equipped to face this new trend in neurotechnology. They concluded that it was not, and that a reconceptualization of human rights is required to protect the individual in the face of the potential for unanticipated consequences or the misuse of neurotechnology.

The information in our brains should be entitled to special protections in this era of ever-evolving technology, he said. When that goes, everything goes.

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neurohacking | emergent by design

Posted: at 3:15 pm

illustration by Kirsten Zirngibl

this post originally appeared on Neurohacker Collective

The term hacker has its origins in computer programming subcultures from the 60s, and was used to describe people who wanted to take on hard problems in a spirit of playful exploration and a resistance to unearned authority. Although the methods, means and intentions of hackers varied widely, all seemed to share a unique ethos that mixed a deep commitment to individual autonomy and agency with an equally deep commitment to collaboration and co-creation.

Over time, the concept of hacking has traveled far from its origins, finding its way into a number of domains like Biohacking, Consciousness Hacking, Flow Hacking and Life Hacking. Each is a kind of hacking because each shares this hackers ethos and a commitment to using it to find the most effective ways to optimize the human experience.

We call the common thread that links these hacking communities together, empowered responsibility. This notion expresses the dual recognition that we are no longer able to rely on external authorities to take care of us (in any domain) but through a combination of ubiquitous information, individual experimentation and open collaboration, we are increasingly empowered to take responsibility for ourselves.

In the Biohacking community, the spirit of empowered responsibility drives the process of optimizing ones biological health and performance. Biohackers learn from each other how they can modify their nutrition, exercise, sleep, movement, and mindset to achieve the specific kind of well-being that they individually desire.

The Consciousness Hacking community takes empowered responsibility in using technology as a catalyst for psychological, emotional and spiritual flourishing. They utilize mindfulness techniques and biofeedback tools for self-exploration, taking personal responsibility for their conscious experience in this most individual of journeys.

Emerging from within and alongside these movements, we are observing the coalescence of a new and important domain: Neurohacking.

Whereas biohacking concentrates on the body, and consciousness hacking explores the inner experience, neurohacking is somewhere in the middle, focusing on the mind-brain interface the intersection of neurology and consciousness. Specifically, neurohacking involves applying science and technology to influence the brain and body in order to optimize subjective experience.

The desired outcomes of neurohacking cover everything from focused productivity, to expanded creativity, more restful sleep, reduced anxiety, enhanced empathy, and anything else that contributes to the psychological well-being and emotional health of whole, thriving human beings.

The technologies of neurohacking run the gamut from chemical technologies like nootropics and entheogens, probiotics to support the gut-brain connection, bioelectrical technologies like neurofeedback and transcranial stimulation, photic therapies like low level laser therapy and all the way to embodied practices like somatics and meditation. So long as there is a scientifically accessible biological mechanism for effecting subjective experience, it belongs in the domain of neurohacking.

Of course, like all emergent phenomena, neurohacking didnt just come from nowhere. For years there have been many movements and communities out there, playing in and pioneering some aspect of the neurohacking space.

Some of these domains include:

We propose that it is now timely and useful to perceive the commonality among these different movements and communities as shared aspects of Neurohacking. And in an effort to make these commonalities more visible and legible to each other, in the upcoming weeks we will take a deeper dive into each, highlight some notable people and projects in each space and explore the frontiers of the community from the point of view of Neurohacking.

In our next post, we will begin this exploration with the domain of Nootropics.

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Vertex (VRTX) Q1 Earnings Top, CF Products Sales Strong – Zacks.com

Posted: at 3:15 pm

Vertex Pharmaceuticals Incorporated (VRTX - Free Report) reported first-quarter 2017 earnings per share of 13 cents (including the impact of stock-based compensation expense), which beat the Zacks Consensus Estimate of 4 cents. Notably, the company had posted a loss of 13 cents in the year-ago quarter. Strong product revenues and cost control led to higher profits in the quarter.

Excluding stock-based compensation expense, first-quarter adjusted earnings were 41 cents per share compared with the year-ago figure of 9 cents.

Including upfront revenues of $230 million received from German phama company, Merck KGaA for the out-licensing of four oncology programs; restructuring costs and other adjustments, reported earnings were 99 cents per share.

Vertex reported revenues of $714.7 million in the first quarter, up 79.5% year over year gaining from the upfront payment from Merck KGaA. Excluding the upfront revenues, adjusted total revenue was $482.3 million, which surpassed the Zacks Consensus Estimate of $459.1 million by 5.3%.

This year so far, Vertexs shares have risen 61.5%, outperforming an increase of 4.8% for the Zacks classified Large-Cap Pharma industry.

CF Franchise Sales Rise

Vertexs first-quarter revenues consisted of sales from cystic fibrosis (CF) products Kalydeco and Orkambi, collaborative ($232.6 million) and royalty revenues ($1.5 million). CF product revenues were $481 million in the first quarter, up 22% year over year.

The company reported a 9% increase in Kalydeco sales to $186 million. Kalydeco sales gained from one-time adjustments mainly related to European reimbursement agreements.

Orkambi (lumacaftor/ivacaftor) delivered sales of $295.0 million, up 32% year over year. On a sequential basis, Orkambi sales rose around 7% in the first quarter supported by rapid uptake in the pediatric indication for which approval was received in Sep 2016.

Cost Discussion

Adjusted (including stock-based compensation expenses) research and development expenses increased 5.9% to $271.4 million in the first quarter due to higher costs related to progress on the CF pipeline. Adjusted (including stock-based compensation expenses) selling, general and administrative (SG&A) expenses increased 5.5% to $110.5 million due to increased investment to support the global launch of Orkambi.

Maintains 2017 Guidance

Vertex maintained its 2017 guidance for Orkambi revenues, which was provided in early Jan 2017, while raising the same for Kalydeco. Orkambi revenues are expected in the range of $1.1$1.3 billion while Kalydeco revenues are estimated in the range of $710 to $730 million, higher than $690$710 million guided previously. Management said the uptick in guidance was the result of a one-time gain received this quarter as well as strong demand trends for the product.

Management continues to believe that Orkambi sales growth will be dependent on reimbursement discussions in Europe in 2017. Vertex has faced many challenges with respect to commercialization of Orkambi in ex-U.S. markets due to re-imbursement hurdles, discontinuations by patients who had previously initiated treatment with Orkambi and a slower-than-anticipated launch in Germany.

Combined adjusted research and development (R&D) and selling, general and administrative (SG&A) expenses in 2017 are anticipated in the range of $1.25$1.30 billion. Costs are expected to be higher than 2016 levels due to increased costs related to CF pipeline development and increased commercial investment to support Orkambi and Kalydeco.

Our Take

Vertexs first-quarter results were strong with the company beating expectations for both earnings and revenues as sales of its CF drugs rose.

Meanwhile, Vertexs CF pipeline is quite strong with a broad portfolio of next-generation CF correctors. Investor focus will now be on the triple combination CF regimens, which are crucial for long-term growth at Vertex. Data from three triple combination regimes in CF patients are expected in the second half of this year. We remind investors that last month, Vertex announced positive data from two phase III studies evaluating Kalydeco in combination with VX-661 (tezacaftor) in patients suffering from CF aged 12 years and above with two copies of the F508del mutation. Both studies EVOLVE and EXPAND met their primary endpoints and demonstrated statistically significant improvements in lung function in patients with CF.Based on positive outcome from the studies, the company is planning to submit regulatory applications in the U.S. and EU in the third quarter of 2017.

Meanwhile, the company is also looking to buy CF candidates, which can be combined with its tezacaftor (VX-661) and Kalydeco to create triple combinations.

Just last month, Vertex announced a definitive deal to buy the worldwide development and commercialization rights of Concert Pharmaceuticals (CNCE - Free Report) CF pipeline candidate, CTP-656 for an upfront payment of $160 million in cash.

Vertex plans to develop CTP-656 for potential use in future once-daily regimens in combination with its other pipeline drugs to treat the underlying cause of CF.

Undoubtedly, the CF market has been attracting the interest of several companies like AbbVie, Pfizer, Inc. (PFE - Free Report) and Sanofi (SNY - Free Report) . These companies are pursuing the development of CFTR potentiators, CFTR correctors and candidates with other mechanisms of action that can address the underlying cause of CF.

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CF Industries to Announce Its 1Q17 Earnings: What to Expect – Market Realist

Posted: at 3:15 pm

CF Industries to Announce Its 1Q17 Earnings: What to Expect PART 1 OF 8

CF Industries (CF), one of the largest producers of nitrogen fertilizers in North America, is set to report its 1Q17 earnings on May 3, 2017, after the market closes. Analysts estimate CFs earnings to come in at -$0.39 per share, which would be a steep decline from $0.40 in 1Q16.

Before we dig deeper into analysts earnings expectations for CF Industries, lets look at how the stock has performed compared to its benchmarks.

On a trailing 52-week basis, CFstock has fallen 15.2% and was trading at $27.20 on April 26, 2017. Among the benchmarks, the VanEck Vector Agribusiness ETF (MOO) has returned 16.8% and the SPDR S&P 500 ETF (SPY) has returned 15.2% over the same period.

Among CF Industries peers, PotashCorp (POT) has fallen 2.2%, while CVR Partners (UAN) has fallen 41.8% over the same period. On the other hand, Agrium (AGU) has returned 5% on a trailing 52-week basis.

In this series, well look at analysts earnings expectations for CF Industries (CF). Well also look at forecasts for some key financial metrics such as revenues, profit margins, and capital outlay over the next 12 months.

Well compare CF Industries valuation multiple with its peers. Well also look at the latest changes in analysts recommendations and price targets for the stock.

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