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Daily Archives: April 25, 2017
Alibaba founder Jack Ma: AI will cause people ‘more pain than happiness’ – The Guardian
Posted: April 25, 2017 at 5:04 am
Jack Ma issued the warning to encourage businesses to adapt or face problems in the future. Photograph: VCG via Getty Images
Artificial intelligence and other technologies will cause people more pain than happiness over the next three decades, according to Jack Ma, the billionaire chairman and founder of Alibaba.
Social conflicts in the next three decades will have an impact on all sorts of industries and walks of life, said Ma, speaking at an entrepreneurship conference in China about the job disruptions that would be created by automation and the internet. A key social conflict will be the rise of artificial intelligence and longer life expectancy, which will lead to an aging workforce fighting for fewer jobs.
Ma, who is usually more optimistic in his presentations, issued the warning to encourage businesses to adapt or face problems in the future. He said that 15 years ago he gave hundreds of speeches warning about the impact of e-commerce on traditional retailers and few people listened because he wasnt as well-known as he is now.
Machines should only do what humans cannot, he said. Only in this way can we have the opportunities to keep machines as working partners with humans, rather than as replacements.
Even so, Ma acknowledged that in the future companies will likely be run by robots.
Machines should only do what humans cannot
Thirty years later, the Time magazine cover for the best CEO of the year very likely will be a robot, he said. Robots can make calculations more quickly and rationally than humans, Ma added, and wont be swayed by emotions, for example by getting angry at competitors.
Leaders who dont understand that cloud computing and artificial intelligence are essential for business should identify young people in their companies to explain it to them, he said.
His comments echo a number of studies suggesting that automation will eliminate jobs, including a Forrester study that suggested 6% of all jobs in the US would be eliminated by 2021. The job displacement will start with customer service representatives and eventually move to truck and taxi drivers, the report read.
Current technologies in this field include virtual assistants, such as Alexa, Cortana, Siri and Google Now, as well as chatbots and automated robotic systems. For now they are quite simple, but over the next five years they will become much better at making decisions on our behalf in more complex scenarios, which will enable mass adoption of breakthroughs, such as self-driving cars.
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Alibaba founder Jack Ma: AI will cause people 'more pain than happiness' - The Guardian
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Artificial Intelligence has to deal with its transparency problems – TNW
Posted: at 5:04 am
Artificial Intelligence breakthroughs and developments entail new challenges and problems. As AI algorithms grow more advanced, it becomes more difficult to make sense of their inner workings. Part of this is because the companies that develop them do not allow the scrutiny of their proprietary algorithms. But a lot of it has to do with the mere fact that AI is becoming opaque due to its increasing complexity.
And this can turn into a problem as we move forward and Artificial Intelligence becomes more prominent in our lives.
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By a long range, AI algorithms perform much better than their human counterparts at the tasks they master. Self driving cars, for instance, which rely heavily on machine learning algorithms, will eventually reduce 90 percent of road accidents. AI diagnosis platforms spot early signs of dangerous illnesses much better than humans, and help save lives. And predictive maintenance can detect signs of wear in machinery and infrastructure in ways that are impossible for humans, preventing disasters and reducing costs.
But AI is not flawless, and does make mistakes, albeit at a lower rate than humans. Last year, the AI-powered opponent in the game Elite Dangerous went berserk and started creating super-weapons to hunt players. In another case, Microsofts AI chatbot Tay started spewing out racist comments within a day of its launch. And remember that time Google face recognition started making some offending labeling of pictures?
None of these mistakes are critical, and the damage can be shrugged off without much thought. However, neural networks, machine learning algorithms, and other subsets of AI are finding their way into more critical domains. Some of these fields include healthcare, transportation and law, where mistakes can have critical and sometimes fatal consequences.
We humans make mistakes all the time, including fatal ones. But the difference here is that we can explain the reasons behind our actions and bear the responsibility. Even the software we used before the age of AI was code and rule-based logic. Mistakes could be examined and reasoned out, and culpability could be well-defined.
The same cant be said of Artificial Intelligence. In particular, neural networks, which are the key component in many AI applications, are something of a black box. Often, not even the engineers can explain why their algorithm made a certain decision. Last year, Googles Go-playing AI stunned the world by coming up with moves that professionals couldnt think of.
As Nils Lenke, Senior Director of Corporate Research at Nuance, says about neural networks, Its not always clear what happens inside you let the network organize itself, but that really means it does organize itself: it doesnt necessarily tell you how it did it.
This can cause problems if those algorithms havefull control in making decisions. Who will be responsible if a self-driving car causes a fatal accident? You cant hold any of the passengers accountable for something they didnt control. And the manufacturers will have a hard time explainingan event that involves so many complexities and variables. And dont expect the car itself to start explaining its actions.
The same can be said of an AI application that has autonomous control over a patients treatment process. Or a risk assessment algorithm that decides whether convicts stay in prison or are free to go.
So can we trust Artificial Intelligence to make decisions on its own? For non-critical tasks, such as advertising, games and Netflix suggestions, where mistakes are tolerable, we can. But for situations where the social, legal, economic and political repercussion can be disastrous, we cant not yet. The same goes for scenarios where human lives are at stake. Were still not ready to forfeit control to the robots.
As Lenke says, [Y]ou need to look at the tasks at hand. For some, its not really critical if you dont fully understand what happens, or even if the network is wrong. A system that suggests music, for example: all that can go wrong is, you listen to boring piece of music. But with applications like enterprise customer service, where transactions are involved, or computer-assisted clinical documentation improvement, what we typically do there is, we dont put the AI in isolation, but we have it co-work with a human being.
For the moment Artificial Intelligence will show its full potential in complementing human efforts. Were already seeing inroads in fields such as medicine and cybersecurity. AI takes care of data-oriented research and analysis and presents human experts with invaluable insights and suggestions. Subsequently, the experts make the decisions and assume responsibility for the possible consequences.
In the meantime, firms and organization must do more to make Artificial Intelligence more transparent and understandable. An example is OpenAI, a nonprofit research company founded by Teslas Elon Musk and YCombinators Sam Altman. As the name suggests, OpenAIs goal is to open AI research and development to everyone, independent of financial interests.
Another organization, Partnership on AI, aims to raise awareness on and deal with AI challenges such as bias. Founded by tech giants including Microsoft, IBM and Google, the Partnership will also work on AI ethics and best practices.
Eventually, well achieve for better or worse Artificial General Intelligence, AI that is on par with the human brain. Maybe then, our cars and robot will be able to go to court and stand trial for their actions. But then, well be dealing with totally different problems.
Thats for the future. In the present, human-dominated world, to make critical decisions, you either have to be flawless or accountable. For the moment, AI falls within none of those categories.
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Artificial Intelligence has to deal with its transparency problems - TNW
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Float tanks gain popularity as alternative medicine – Eagle News
Posted: at 5:03 am
Sensory deprivation tanks, more commonly known as float tanks, offer alternative approaches to improve mental and physical health.
Float tanks are light less, soundproof tanks filled with Epsom salt water.
The water is set at skin temperature and the individual can float effortlessly.
There are two float tank therapy locations near FGCU, The Float & Flourish Center in Bonita Springs and Cloud9 Float and Spa.
The Float & Flourish Center serves as almost a modernized day spa, with services including float therapy, oxygen bar and infrared sauna therapy. Cloud9 Float and Spa is located in Naples and offers the same experience.
According to the Journal of Psychology and Health, sensory deprivation is the purposeful removal of stimuli to one or more of the human senses.
This can lead to a relaxed state, even falling into a state of meditation.
This medical technique is called Restricted Environmental Stimulation Therapy.
Developed in the 1950s by neuropsychiatrist John C. Lily, Float Tanks would see its first surge in popularity in the 1980s with the release of the film Altered States.
According to a 1981 New York Times article, about $4 million in sales were made in 1981.
However, with the fear and rise of the AIDS epidemic in the 1980s, the popularity dimmed.
A study done by the European Journal of Integrative Medicine saw patients show improvements in physiological changes, alleviation of medical conditions, relaxation, personal growth and enhancement and an altered state of consciousness.
According to the Journal of Psychology and Health, a study showed to improve cortisol levels and lowered blood pressure.
Floatation therapy soothes muscle pain, cleanses pores and detoxifies the skin, said Guillermo Fernandez, owner of the Float & Flourish Center in Bonita Springs. It helps everyone. From high level athletes, to the everyday person with no athletic experience. Float tanks are one of the most effective stress-management techniques available.
Current and former high-level athletes have been known to use float tanks to aid in athletic performance.
Carl Lewis used float tanks to help him train for his long jump in the 1988 Olympics.
Golden State Warriors basketball player, Steph Curry said in an interview with CNN that he uses float tanks every two weeks.
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Float tanks gain popularity as alternative medicine - Eagle News
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Fraser Institute News Release: Nearly eight in ten Canadians have used alternative medicines: survey – Marketwired (press release)
Posted: at 5:03 am
VANCOUVER, BC--(Marketwired - April 25, 2017) - More and more Canadians are using complementary and alternative medicines and therapies -- such as massage, yoga, acupuncture and chiropractic care -- and they're using them more frequently, finds a new survey by the Fraser Institute, an independent, non-partisan Canadian public policy think-tank.
"Alternative treatments are playing an increasingly important role in Canadians' overall health care, and understanding how all the parts of the health-care system fit together is vital if policymakers are going to find ways to improve it," said Nadeem Esmail, Fraser Institute senior fellow and co-author of Complementary and Alternative Medicine: Use and Public Attitudes, 1997, 2006 and 2016.
The updated survey of 2,000 Canadians finds more than three-quarters of Canadians -- 79 per cent -- have used at least one complementary or alternative medicine (CAM) or therapy sometime in their lives. That's an increase from 74 per cent in 2006 and 73 per cent in 1997, when two previous similar surveys were conducted.
In fact, more than one in two Canadians (56 per cent) used at least one complementary or alternative medicine or therapy in the previous 12 months, an increase from 54 per cent in 2006 and 50 per cent in 1997.
And Canadians are using those services more often, averaging 11.1 visits in 2016, compared to fewer than nine visits a year in both 2006 and 1997.
The most popular complementary and alternative treatments used by Canadians in 2016 were massage (44 per cent), followed by chiropractic care (42 per cent), yoga (27 per cent), relaxation techniques (25 per cent) and acupuncture (22 per cent.)
In total, Canadians spent $8.8 billion on complementary and alternative medicines and therapies last year, up from $8 billion (inflation adjusted) in 2006.
Interestingly, the survey finds a majority of respondents -- 58 per cent -- support paying for alternative treatments privately and don't want them included in provincial health plans. Support for private payment is highest (at 69 per cent) among 35- to 44-year-olds.
"Complementary and alternative therapies play an increasingly important role in Canadians' overall health care, but policy makers should not see this as an invitation to expand government coverage -- the majority of Canadians believe alternative therapies should be paid for privately," Esmail said.
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Fraser Institute
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The Fraser Institute is an independent Canadian public policy research and educational organization with offices in Vancouver, Calgary, Toronto, and Montreal and ties to a global network of think-tanks in 87 countries. Its mission is to improve the quality of life for Canadians, their families and future generations by studying, measuring and broadly communicating the effects of government policies, entrepreneurship and choice on their well-being. To protect the Institute's independence, it does not accept grants from governments or contracts for research. Visit http://www.fraserinstitute.org
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Bill Nye Spends Most of His New Netflix Show Yelling at the Audience – Gizmodo
Posted: at 5:03 am
If youre skeptical about human-caused climate change or the safety of vaccines, would being berated in front of a live studio audience by a bombastic old man make you change your mind? Then congratulations, Bill Nyes new Netflix show, Bill Nye Saves The World, is literally just for you!
Wait...whered you go, bud?
I was excited when I heard that a new science show for adults was hitting Netflix, especially one starring 90s-kid nerd hero Bill Nye. But either the science guys jokes havent aged well or his schticka zany dad-figure in a lab coat stirring beakers full of colored liquidsdoesnt quite work when hes bellowing, red-faced, about the dangers of climate change denial, alternative medicine, and the anti-vaxxer movement. While seemingly aimed at the average layman who holds some science-skeptical views, Nyes new show delivers delivers so little information in such a patronizing tone its hard to imagine a toddler, let alone a sentient adult, enjoying it.
The format of the showwhich blends live studio interviews, field reporting, and Nye shouting into camera on subjects ranging from artificial intelligence to GMOsdoes have potential. Many of the studio guests are interesting and engaging. For instance, the first episode, which focuses on climate change and energy, features Mark Jacobson, a Stanford engineer who recently authored a paper on how we could run the entire world on renewables by mid-century. It would have been fascinating to hear Jacobson give a detailed summary of his idea for transforming the energy gridand Im sure he would have been happy to oblige.
Instead, we watched for an excruciating five minutes as Nye pitted Jacobson against another of his round table guests, energy and environment reporterRichard Martin, to explain at a ten-year-old level why Martin is like, totally wrong and dumb for thinking nuclear power should be part of our energy future, too. The entire exchange was apparently intended to bolster the (not exactly scientific) viewpoint Nye interjected throughout the segment, that nobody wants nuclear power.
This, unfortunately, is quintessential of the showa small amount of information packaged to promote a cartoon-caricature understanding of a complex science issue, slanted to the POV of an unabashedly political science comedian.
During Episode 2, which debunks alternative medicine, Nye and science communicator Cara Santa Maria repeatedly gang up on another guest, the mild-mannered filmmaker Donald Schultz, when he suggests that some non-Western medicine practices might not be entirely bogus. In a later episode focused on GMOs, correspondent Derek Muller visits a farmers market to interview some crunchy hippie-types about whether or not they consider genetic modification safe. Mullers interviews are packaged into a sort of freak-show highlight reel, which Netflix viewers get to cringe at alongside the studio audience, the crowd roaring with laugher every time one of the hapless veggie-lovers says something silly.
Are you feeling pumped about science yet?!
To be fair, I havent watched every single episode, and most of them do seem to have one or two solid segments. Muller visiting the Jet Propulsion Laboratory to speak with astrobiologists about the search for life on Mars, or traveling to South Korea to discover how K-pop is transforming views on gender identity and sexuality, were both palatable and mildly informative. And every now and then, the show manages to be downright funny, like when wrestling champion Ryan Couture is trotted on stage dressed as an indestructible tardigrade. As Gizmodo space writer Rae Paoletta put it, that single handedly saved the [space] episode.
Most of the entertaining bits share a common theme. The angry science man is nowhere near them.
Let me be clear. I believe climate change is real and human-caused, I believe that vaccines work, and I believe that most alternative medicine is a load of malarkey. Like Nye, Im outraged to see anti-science beliefs promulgated at the highest levels of our government. Nye and I are on the same teamand yet I still felt like I was being talked down to throughout his show. How will the average viewer feel?
Perhaps, theyll feel a bit like the live studio audience, laughing nervously during Nyes tirade about how Miamis going to be underwater if we dont get our collective shit together, and wishing they could be anywhere else.
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The ethics of new age medicine – Catholic San Francisco
Posted: at 5:03 am
Patients who face serious illnesses are sometimes attracted to alternative medicines, also referred to as holistic or new age medicines. These can include treatments like homeopathy, hypnosis, energy therapies like Reiki, acupuncture, and herbal remedies, to name just a few.
These approaches raise various medical and ethical concerns. An important 1998 article in the New England Journal of Medicine sums it up this way:
What most sets alternative medicine apart, in our view, is that it has not been scientifically tested and its advocates largely deny the need for such testing. By testing, we mean the marshaling of rigorous evidence of safety and efficacy, as required by the Food and Drug Administration for the approval of drugs and by the best peer-reviewed medical journals for the publication of research reports.
Beyond the fact that their clinical efficacy has not earned a passing grade using ordinary methods of scientific investigation, the basic premise behind some alternative medicines can also be highly suspect, raising concerns about superstitious viewpoints or misguided forms of spirituality motivating certain therapies.
If we consider acupuncture, this technique does appear to provide benefit in certain cases of pain control. Yet similar results have been reported using sham needles tapping the skin in random places with a thin metal tube. Brain scans have demonstrated that treatment with genuine needles, as opposed to the sham needles, does cause detectable changes in the brain. But, when researchers ignored acupuncturists recommended meridian placement of needles, and instead did random placement in the skin, the same brain effects were observed. Hence, it is unclear whether the results seen from acupuncture arise mostly from the well-known placebo effect or not. Further research should help resolve this question.
Even if the observed effects are not placebo-related, acupunctures non-rational justification for its purported effectiveness remains a concern. It is based on energy principles that neither science nor faith affirm. Dr. Glenn Braunstein described it critically in the following way:
Chi, the invisible nutritive energy that flows from the universe into the body at any one of 500 acupuncture points, is conducted through the 12 main meridians [channels] in (ideally) an unbroken circle. Meridians conduct either yin energy (from the sun) or yang energy (from the earth). All maladies are caused by disharmony or disturbances in the flow of energy.
Clearly, then, some alternative therapies, beyond the basic issue about whether they work, raise serious spiritual concerns as well.
Another new age therapy known as reiki, developed in Japan in the late 1800s, claims that sickness can be caused by a disruption or imbalance in a patients reiki or life energy. Reiki practitioners try to heal a patient by placing their hands in certain positions on the body in order to facilitate the flow of reiki from the practitioner to the patient.
A 2009 document from the U.S. Conference of Catholic Bishops stresses, In terms of caring for ones spiritual health, there are important dangers that can arise by turning to reiki. The document notes that because reiki therapy is not compatible with either Christian teaching or scientific evidence, it would be inappropriate for Catholics to put their trust in the method, because to do so would be to operate in the realm of superstition, the no-mans-land that is neither faith nor science.
Scientific investigations of another new age therapy, the popular herbal remedy known as echinacea (taken early to ward off a cold) have revealed no difference between echinacea and a placebo in controlled studies involving several hundred subjects. While some herbal remedies may be harmless and inert placebos, others may have more serious health consequences if ingested above certain dosages due to ingredients of unknown potency derived from natural substances.
Sometimes a remedy can be borrowed from Chinese, Indian or another medical tradition, but it should be chosen for its efficacy, safety, and reasonable mode of action, and not be in conflict with principles of sound medical science or Christian teaching.
Health improvements that arise from alternative remedies may be due not only to the placebo effect, but also to the fact that patients are usually given more time, attention and focused concern by alternative practitioners than by traditional physicians. This can translate into modified habits and changed lifestyles, leading to various health benefits.
Modern medicine can be legitimately faulted for downplaying this dimension, so that, in the memorable words of pediatrician Jay Perman, Doctors tend to end up trained in silos of specialization, in which they are taught to make a diagnosis, prescribe a therapy, and were done. But were not done.
The famous Greek physician Hippocrates once noted the same point: It is more important to know what sort of person has a disease than to know what sort of disease a person has. Todays physicians-in-training, fortunately, are seeking to incorporate more and more of these patient-centric and holistic aspects into their own traditional medical practices to improve patient care and outcomes.
Father Pacholczyk is a priest of the Diocese of Fall River, Massachusetts, and director of education at The National Catholic Bioethics Center, Philadelphia.
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Common Food Nutrient Tied to Risky Blood Clotting – Bloomington Pantagraph
Posted: at 5:02 am
MONDAY, April 24, 2017 (HealthDay News) -- A nutrient in meat and eggs may conspire with gut bacteria to make the blood more prone to clotting, a small study suggests.
The nutrient is called choline. Researchers found that when they gave 18 healthy volunteers choline supplements, it boosted their production of a chemical called TMAO.
That, in turn, increased their blood cells' tendency to clot. But the researchers also found that aspirin might reduce that risk.
TMAO is short for trimethylamine N-oxide. It's produced when gut bacteria digest choline and certain other substances.
Past studies have linked higher TMAO levels in the blood to heightened risks of blood clots, heart attack and stroke, said Dr. Stanley Hazen, the senior researcher on the new study.
These findings, he said, give the first direct evidence that choline revs up TMAO production in the human gut, which then makes platelets (a type of blood cell) more prone to sticking together.
Choline is found in a range of foods, but it's most concentrated in animal products such as egg yolks, beef and chicken.
Hazen said he and his colleagues at the Cleveland Clinic wanted to isolate the effects of choline on people's levels of TMAO and their platelet function. So they studied supplements.
The researchers had 18 healthy adults --10 meat-eaters and eight vegetarians/vegans -- take choline supplements for two months.
The supplements provided around 450 milligrams of choline daily -- roughly the amount in two or three eggs, Hazen said.
One month in, the study found, the supplements had raised participants' TMAO levels 10-fold, on average. And tests of their blood samples showed that their platelets had become more prone to clotting.
"This study gives us one of the mechanisms by which TMAO may contribute to cardiovascular disease," said Dr. J. David Spence.
Spence, who was not involved in the study, directs the Stroke Prevention & Atherosclerosis Research Centre at Western University in London, Ontario, Canada.
For the healthy people in this study, Spence said, the TMAO rise from choline might not be worrisome. But, he added, it might be a concern for people at increased risk of heart disease or stroke.
Spence suggested those individuals limit egg yolks, beef and other foods high in choline.
Hazen had similar advice. "You don't have to become a vegetarian," he said. "But you could try eating more plant-based foods, and more vegetarian meals."
He also pointed to the Mediterranean diet -- rich in olive oil, vegetables and fish. In an earlier study, Hazen said, his team found that a compound in olive oil seems to inhibit TMAO formation.
The new study uncovered yet another compound that may counter TMAO: low-dose aspirin.
In a separate experiment, the researchers had some participants take 85 milligrams of aspirin (a baby aspirin) a day, in addition to choline supplements. That, it turned out, lessened the rise in TMAO and the change in platelet activity.
Doctors already prescribe low-dose aspirin to certain people at risk of heart disease and stroke.
It's possible, Hazen said, that aspirin's effects on TMAO are one reason it helps ward off cardiovascular trouble.
The current study is small and preliminary. But it's the latest to suggest that the gut "microbiome" plays a key role in cardiovascular disease, Spence said.
The "microbiome" refers to the trillions of bacteria that dwell in the gut. Spence said researchers are just beginning to understand how gut bacteria and their byproducts affect the cardiovascular system.
But one hope, he said, is to figure out what balance of gut bacteria supports cardiovascular health -- and possibly use probiotic ("good" bacteria) supplements to help treat people at high risk of heart disease or stroke.
Spence said his own lab is working on just that.
There are, of course, many factors in heart disease risk -- from age to high blood pressure to diabetes to smoking, Hazen pointed out.
"We're saying a portion of the risk is related to the gut microbiome," he said.
Hazen and a colleague report potential royalty payments from several companies related to "cardiovascular diagnostics and therapeutics." One company, Cleveland HeartLab, recently launched a test for measuring TMAO levels.
The findings appear in the April 25 online issue of Circulation.
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Common Food Nutrient Tied to Risky Blood Clotting - Bloomington Pantagraph
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Doctor’s Tip: Get vitamins from your food, not pills – Glenwood Springs Post Independent
Posted: at 5:02 am
As discussed in the last two columns, vitamins are substances necessary in trace amounts for normal metabolic functioning of cells and the human body. With two exceptions, vitamins are made by plants, although because animals eat plants, vitamins are present in some animal products. The two exceptions are vitamin B12 made by bacteria in dirt, and vitamin D produced by our bodies when exposed to sun. Last week's column was about vitamin B12 and the health tip column two weeks ago was about vitamin D.
How about minerals and other vitamins? They are clearly important for optimal health. In the distant past people suffered from diseases such as scurvy caused by lack of vitamin C, and beriberi due to deficiency of vitamin B1 (thiamine). In our part of the world, diseases due to deficiency of vitamins other than D and B12 are rare now.
In Western societies we like to practice what T. Colin Campbell, Ph.D. (featured in the documentary "Forks Over Knives," author of "The China Study") calls reductionism. Different foods have been shown to cause certain health benefits, and we like to find the "magic bullet" responsible for these benefits, put it in a pill or capsule, market it and make millions in profits.
The problem is that nutrition doesn't work that way. There are thousands of vitamins and other nutrients in various unprocessed plant foods, many of which remain unknown, and many of which work synergistically when the whole food is consumed. As Dr. Esselstyn (also featured in "Forks Over Knives," author of "Prevent and Reverse Heart Disease") puts it, if we eat a "symphony of plant-based food" our bodies have an amazing way of taking out what we need.
You cannot get the same thing in pill or capsule form. For example people who eat plants rich in vitamin E have less heart disease, but high doses of vitamin E in pill form cause heart disease. Vitamin A-containing food helps prevent cancer, but high doses in pill form increase certain cancers. Joel Fuhrman, M.D., author of several books including "Eat to Live," notes that folic acid is the synthetic form of folate added to food and used in vitamin supplements. Whole foods with natural folate prevent disease, whereas "evidence suggests that folic acid supplementation may significantly increase the risk of cancer."
Regarding minerals, In his book "Power Foods For The Brain" Neal Barnard, M.D. points out that:
The amount of copper we need is 0.9 mg, which can easily be obtained by eating greens, nuts, whole grains and mushrooms. There is evidence that larger doses from supplements or from cookware may contribute to Alzheimer's.
Daily iron requirements can be obtained by eating greens, beans, whole grains and dried fruits, but too much from supplements and cookware may contribute to Alzheimer's. (Note that women with heavy menses might need to supplement if their red blood count is low.)
We need 8-11 mg of zinc daily, with healthy sources being oatmeal, whole-grain bread, brown rice, peanuts, beans, nuts, peas and sesame seeds. Too much in pill form may contribute to Alzheimer's.
Many studies have proven that vitamin/mineral supplements are not beneficial and may even be harmful. Yet one-third of Americans take these products and spend billions of dollars doing so. Here's the bottom line:
As discussed in the previous two columns, many Americans are deficient in vitamin B12 and D and should therefore supplement (read the articles to find out the details).
We should be getting other vitamins and trace minerals the way we evolved to get them: in our food, by eating a variety of vegetables, fruit and whole grains.
If you eat animal products, eat more plant-based foods as well.
You cannot get from pills what you can get by eating a healthy diet.
A couple of caveats:
We should avoid salt because it harms the endothelial lining of blood vessels and eventually leads to high blood pressure. Years ago, in order to prevent goiters, guidelines were put in place to add iodine to commercial salt. If you don't eat salt you can get iodine by eating seaweed every day, by eating Eden brand canned beans (contain a tiny bit of kelp), or by taking a 150 microgram supplement of iodine a day (especially important in pregnant and breast-feeding women).
If you are plant-based and want more details about vitamins and minerals, Dr. Michael Greger (nutritionfacts.org, author of "How Not to Die") recommends a reference book by "the pre-eminent dietitians" Brenda Davis and Vesanto Melina called "The Complete Guide to Adopting a Plant-Based Diet."
Dr. Feinsinger, who retired from Glenwood Medical Associates after 42 years as a family physician, now has a nonprofit Center For Prevention and Treatment of Disease Through Nutrition. He is available for free consultations about heart attack prevention and any other medical concerns. Call 970-379-5718 for an appointment. For questions about his columns, email him at gfeinsinger@comcast.net.
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Doctor's Tip: Get vitamins from your food, not pills - Glenwood Springs Post Independent
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PhytoClean Solvent-Free Extraction Process Gets Top Billing in Commercial Launch from Life Extension – Nutritional Outlook
Posted: at 5:02 am
The first-ever retail product advertising the PhytoClean solvent-free extraction process is now on the market, says Mazza Innovation (Delta, BC, Canada), innovator of the PhytoClean method. The product is Life Extensions Mediterranean Whole Food Blend, an extract blend standardized to 25% polyphenols from grapes, olives, pomegranates, black walnuts, pecans, artichokes, and lentils.
PhytoClean is a unique, proprietary, environmentally friendly extraction process using water and no chemical solvents. Mazza describes the process this way: PhytoClean employs an environmentally responsible extraction method that applies heat and pressure to water to lower its polarity, causing it to behave like an organic solvent. The firm says that pressurizing water at moderate temperatures enables the water to better solubilize bioactive compoundsso much so, the company says, that it generally provides better yields and purities than industrial solvents.
Life Extensions label for Mediterranean Whole Food Blend promotes PhytoClean front and Center, advertising the product as a farm-to-capsule blend using PhytoClean technology.
This is a significant milestone for Mazza, as Life Extensions Mediterranean Whole Food Blend is the first product on the market to carry the PhytoClean seal on the label to meet its solvent-free and clean-label standard, said Benjamin Lightburn, president of Mazza Innovation, in a press release.
Mazzas PhytoClean extraction process uses only water, and this ensures that Life Extensions Mediterranean Whole Food Blend has superior ingredients, without unnecessary additives, said Andrew Swick, PhD, senior vice president, product development and scientific affairs, Life Extension, in the same press release.
Also read:
Is Mazzas Solvent-Free Extraction the New Standard?
Jennifer Grebow Editor-in-Chief Nutritional Outlook magazine jennifer.grebow@ubm.com
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Life Extension and Insilico Medicine Use AI to Develop Ageless Cell – WholeFoods Magazine
Posted: at 5:02 am
Fort Lauderdale, FL Life Extension has partnered with Insilico Medicine to introduce Ageless Cell, the first supplement in its GEROPROTECT line to promote healthy aging by inhibiting cellular senescence.
Cellular senescence is a natural part of the aging process where cells no longer function optimally, affecting organ function, cellular metabolism, and inflammatory response. The accumulation of these senescent cells contributes to the process of aging. The Ageless Cell supplements inhibit the effects of cellular senescence by acting as geroprotectors, or interventions aimed to increase longevity and impede the onset of age-related diseases by targeting and inhibiting senescence-inducing pathways and inhibiting the development of senescent cells.
The partnership with Insilico Medicine allowed researchers to use deep learning algorithms to comb through hundreds of studies and thousands of data points a process that could have taken decades to identify four key anti-aging nutrients: N-Acetyl-L-Cysteine (NAC), myricetin, gamma-tocotrienol, and EGCG. These compounds target pathways that are known to contribute to or protect against the development of senescent cells.
Specifically, NAC upregulates signaling pathways that protect cells against oxidative stress, which promotes cellular senescence. It also reduces pathways that promote inflammation. Myricetin regulates a family of stress-responsive signaling molecules known to regulate aging in many tissues. It also promotes cell differentiation and self-repair. Gamma tocotrienol modulates the mevalonate pathway that controls cholesterol production, cancer promotion, and bone formation. And EGCG regulates the Wnt pathway that determines the fate of developing cells and also prevents sugar-induced damage to tissues, helping to suppress their pro-aging effects.
Clinical aging studies are extremely difficult, if not impossible, to perform at this time. Our collaboration with Insilico Medicine has allowed us to develop geroprotective formulations by using artificial intelligence to study very large data sets, said Andrew G. Swick, Ph.D., senior vice president of product development and scientific affairs for Life Extension.
Scientists found these four nutrients have various complementary and reinforcing properties to influence key anti-aging pathways and combat aging factors by modulating specific biological pathways. By rejuvenating near-senescent cells and encouraging the bodys healthy process for dealing with senescent cells, Ageless Cell turns back the clock at the cellular level, said Michael A. Smith, M.D., senior health scientist for Life Extension. Alex Zhavoronkov, Ph.D., CEO of Insilico Medicine said, Together, these four natural compounds represent the beginning of the future anti-aging cocktails identified using artificial intelligence under expert human supervision.
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Life Extension and Insilico Medicine Use AI to Develop Ageless Cell - WholeFoods Magazine
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